#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P14576 uniprotkb:P09132 intact:EBI-8428927|intact:MINT-247596|uniprotkb:Q9D008|uniprotkb:Q9CWH7|uniprotkb:Q3UWX8|ensembl:ENSMUSP00000021407|ensembl:ENSMUSP00000106336|ensembl:ENSMUSP00000152764 intact:EBI-2680090|uniprotkb:B2R4E9|uniprotkb:Q96FG6|uniprotkb:Q05D77|uniprotkb:D6RCQ5|ensembl:ENSP00000424870 psi-mi:srp54_mouse(display_long)|uniprotkb:Srp54(gene name)|psi-mi:Srp54(display_short) psi-mi:srp19_human(display_long)|uniprotkb:SRP19(gene name)|psi-mi:SRP19(display_short) psi-mi:"MI:0114"(x-ray crystallography) Kuglstatter et al. (2002) mint:MINT-6948905|pubmed:12244299|doi:10.1038/nsb843 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8533188|mint:MINT-6949182 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001093579.1|refseq:NP_036029.2|ensembl:ENSMUSG00000073079(gene)|ensembl:ENSMUSG00000112449(gene)|ensembl:ENSMUST00000021407(transcript)|ensembl:ENSMUST00000110708(transcript)|ensembl:ENSMUST00000220578(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008312"(7S RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019003"(GDP binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004125(Signal recognition particle, SRP54 subunit, M-domain)|interpro:IPR006325(Signal recognition particle, SRP54 subunit)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|interpro:IPR022941|interpro:IPR027417|interpro:IPR036891|interpro:IPR042101|mint:P14576|rcsb pdb:1RY1|rcsb pdb:1WGW|reactome:R-MMU-1799339|mint:MINT-6949184(identity) refseq:NP_001191123.1|refseq:NP_003126.1|refseq:NP_001191122.1|refseq:NP_001191125.1|ensembl:ENSG00000153037(gene)|ensembl:ENST00000505459(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006617"(SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition)|go:"GO:0008312"(7S RNA binding)|go:"GO:0048500"(signal recognition particle)|interpro:IPR002778(Signal recognition particle, SRP19 subunit)|interpro:IPR036521|mint:P09132|rcsb pdb:1JID|rcsb pdb:1MFQ|rcsb pdb:1RY1|rcsb pdb:2J37|rcsb pdb:3KTV|rcsb pdb:4P3E|rcsb pdb:5M73|rcsb pdb:7NFX|reactome:R-HSA-1799339|dip:DIP-41412N|mint:MINT-6949185(identity) - comment:mint|function:"Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein)" - figure legend:F1|comment:In the xray complex 1mfq, P09132 is chain B and P14576 is chain C Resolution 3.100|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/02/24 2014/10/16 rogid:izjPSrxa4r6+T8pmv0YJx98fdbw10090 rogid:yIFmf1q6m2wQt3eaiCc1dlIQXn89606 intact-crc:BEE738BA1C9BDFCD|rigid:RE3UDGlm9tQ6sv4SRF1UApjPS0E false tag:?-?(MINT-6949191) tag:?-?(MINT-6949188) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)