#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P53064 uniprotkb:P38439 intact:EBI-16303|uniprotkb:P89115|ensemblfungi:YGL244W|uniprotkb:D6VV91 intact:EBI-10108|uniprotkb:D6W2I1|ensemblfungi:YOR123C psi-mi:rtf1_yeast(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:YGL244W(locus name)|uniprotkb:HRA458(orf name)|uniprotkb:CSL3(gene name synonym) psi-mi:leo1_yeast(display_long)|uniprotkb:O3278(orf name)|uniprotkb:YOR3278C(orf name)|uniprotkb:YOR123C(locus name)|uniprotkb:LEO1(gene name)|psi-mi:LEO1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Squazzo et al. (2002) pubmed:11927560|imex:IM-19478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2436762|imex:IM-19478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001160"(regulation of histone H3-K79 methylation)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR004343(Plus-3)|interpro:IPR036128|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|rcsb pdb:5E8B|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0042138"(meiotic DNA double-strand break formation)|rcsb pdb:5EMX|ensemblfungi:YGL244W(gene)|ensemblfungi:YGL244W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_011270.1|sgd:S000003213|dip:DIP-4065N|mint:P53064 refseq:NP_014766.1|sgd:S000005649|ensemblfungi:YOR123C(gene)|ensemblfungi:YOR123C_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0006325"(chromatin organization)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR007149(Leo1-like protein)|go:"GO:0005634"(nucleus)|reactome:R-SCE-674695|reactome:R-SCE-75955|dip:DIP-4143N|mint:P38439 - crc64:13AECCEC6D63CED4 crc64:ABDE3D7D5A2C78A5 figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/18 2014/10/16 rogid:jPawNxTgh9wPA5Uxbn5QCUeDw9Q559292 rogid:qhB5pVP3l4WqXtp3JhmPsxEVHE0559292 intact-crc:0FDBB233D6DC10EC|rigid:1SWXvR6pKCqs7TIno0BCMpmXBTI false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P53064 uniprotkb:P38351 intact:EBI-16303|uniprotkb:P89115|ensemblfungi:YGL244W|uniprotkb:D6VV91 intact:EBI-12855|uniprotkb:Q9URC9|uniprotkb:D6VQS4|ensemblfungi:YBR279W psi-mi:rtf1_yeast(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:YGL244W(locus name)|uniprotkb:HRA458(orf name)|uniprotkb:CSL3(gene name synonym) psi-mi:paf1_yeast(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:YBR279W(locus name)|uniprotkb:YBR2016(orf name)|uniprotkb:Protein PAF1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Squazzo et al. (2002) pubmed:11927560|imex:IM-19478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2436762|imex:IM-19478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001160"(regulation of histone H3-K79 methylation)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR004343(Plus-3)|interpro:IPR036128|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|rcsb pdb:5E8B|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0042138"(meiotic DNA double-strand break formation)|rcsb pdb:5EMX|ensemblfungi:YGL244W(gene)|ensemblfungi:YGL244W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_011270.1|sgd:S000003213|dip:DIP-4065N|mint:P53064 ensemblfungi:YBR279W(gene)|ensemblfungi:YBR279W_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006364"(rRNA processing)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_009838.1|sgd:S000000483|mint:P38351|dip:DIP-1149N - crc64:13AECCEC6D63CED4 - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/18 2014/10/16 rogid:jPawNxTgh9wPA5Uxbn5QCUeDw9Q559292 rogid:k4kVCyYuA4w4+4OEroTkwhbxs6Q559292 intact-crc:0FDBB233D6DC10EC|rigid:1SWXvR6pKCqs7TIno0BCMpmXBTI false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P53064 uniprotkb:P89105 intact:EBI-16303|uniprotkb:P89115|ensemblfungi:YGL244W|uniprotkb:D6VV91 intact:EBI-5283|uniprotkb:O14409|uniprotkb:Q07332|uniprotkb:Q08292|uniprotkb:D6W1S4|ensemblfungi:YOL145C psi-mi:rtf1_yeast(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:YGL244W(locus name)|uniprotkb:HRA458(orf name)|uniprotkb:CSL3(gene name synonym) psi-mi:ctr9_yeast(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:CDP1(gene name synonym)|uniprotkb:Cln three-requiring protein 9(gene name synonym)|uniprotkb:Centromere-binding factor 1-dependent protein 1(gene name synonym)|uniprotkb:YOL145C(locus name) psi-mi:"MI:0676"(tandem affinity purification) Squazzo et al. (2002) pubmed:11927560|imex:IM-19478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2436762|imex:IM-19478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001160"(regulation of histone H3-K79 methylation)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR004343(Plus-3)|interpro:IPR036128|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|rcsb pdb:5E8B|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0042138"(meiotic DNA double-strand break formation)|rcsb pdb:5EMX|ensemblfungi:YGL244W(gene)|ensemblfungi:YGL244W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_011270.1|sgd:S000003213|dip:DIP-4065N|mint:P53064 refseq:NP_014496.2|sgd:S000005505|dip:DIP-2814N|mint:P89105|ensemblfungi:YOL145C(gene)|ensemblfungi:YOL145C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0035327"|go:"GO:0045142"(triplex DNA binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955 - crc64:13AECCEC6D63CED4 crc64:F794ECBAD26D4820 figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/18 2014/10/16 rogid:jPawNxTgh9wPA5Uxbn5QCUeDw9Q559292 rogid:85qAqldtQL8T7JBgNxrvAYtHhd0559292 intact-crc:0FDBB233D6DC10EC|rigid:1SWXvR6pKCqs7TIno0BCMpmXBTI false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P53064 uniprotkb:Q06697 intact:EBI-16303|uniprotkb:P89115|ensemblfungi:YGL244W|uniprotkb:D6VV91 intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C psi-mi:rtf1_yeast(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:YGL244W(locus name)|uniprotkb:HRA458(orf name)|uniprotkb:CSL3(gene name synonym) psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:"MI:0676"(tandem affinity purification) Squazzo et al. (2002) pubmed:11927560|imex:IM-19478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2436762|imex:IM-19478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001160"(regulation of histone H3-K79 methylation)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR004343(Plus-3)|interpro:IPR036128|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|rcsb pdb:5E8B|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0042138"(meiotic DNA double-strand break formation)|rcsb pdb:5EMX|ensemblfungi:YGL244W(gene)|ensemblfungi:YGL244W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_011270.1|sgd:S000003213|dip:DIP-4065N|mint:P53064 refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955 - crc64:13AECCEC6D63CED4 crc64:9580B53EEFB75345 figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/18 2014/10/16 rogid:jPawNxTgh9wPA5Uxbn5QCUeDw9Q559292 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 intact-crc:0FDBB233D6DC10EC|rigid:1SWXvR6pKCqs7TIno0BCMpmXBTI false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P53064 uniprotkb:P27692 intact:EBI-16303|uniprotkb:P89115|ensemblfungi:YGL244W|uniprotkb:D6VV91 intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W psi-mi:rtf1_yeast(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:YGL244W(locus name)|uniprotkb:HRA458(orf name)|uniprotkb:CSL3(gene name synonym) psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Squazzo et al. (2002) pubmed:11927560|imex:IM-19478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2436778|imex:IM-19478-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001160"(regulation of histone H3-K79 methylation)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR004343(Plus-3)|interpro:IPR036128|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|rcsb pdb:5E8B|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0042138"(meiotic DNA double-strand break formation)|rcsb pdb:5EMX|ensemblfungi:YGL244W(gene)|ensemblfungi:YGL244W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_011270.1|sgd:S000003213|dip:DIP-4065N|mint:P53064 refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692 - crc64:13AECCEC6D63CED4 crc64:E4324DB6B1E4721A figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/18 2014/10/16 rogid:jPawNxTgh9wPA5Uxbn5QCUeDw9Q559292 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 intact-crc:66C78094EB1E2895|rigid:iyQChulXg9mWQohRg0OJlckkIVE false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53064 uniprotkb:P04050 intact:EBI-16303|uniprotkb:P89115|ensemblfungi:YGL244W|uniprotkb:D6VV91 intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C psi-mi:rtf1_yeast(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:YGL244W(locus name)|uniprotkb:HRA458(orf name)|uniprotkb:CSL3(gene name synonym) psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Squazzo et al. (2002) pubmed:11927560|imex:IM-19478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2436778|imex:IM-19478-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001160"(regulation of histone H3-K79 methylation)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR004343(Plus-3)|interpro:IPR036128|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|rcsb pdb:5E8B|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0042138"(meiotic DNA double-strand break formation)|rcsb pdb:5EMX|ensemblfungi:YGL244W(gene)|ensemblfungi:YGL244W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_011270.1|sgd:S000003213|dip:DIP-4065N|mint:P53064 refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519 - crc64:13AECCEC6D63CED4 crc64:A45C1360FF99F968 figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/18 2014/10/16 rogid:jPawNxTgh9wPA5Uxbn5QCUeDw9Q559292 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 intact-crc:66C78094EB1E2895|rigid:iyQChulXg9mWQohRg0OJlckkIVE false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53064 uniprotkb:P38351 intact:EBI-16303|uniprotkb:P89115|ensemblfungi:YGL244W|uniprotkb:D6VV91 intact:EBI-12855|uniprotkb:Q9URC9|uniprotkb:D6VQS4|ensemblfungi:YBR279W psi-mi:rtf1_yeast(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:YGL244W(locus name)|uniprotkb:HRA458(orf name)|uniprotkb:CSL3(gene name synonym) psi-mi:paf1_yeast(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:YBR279W(locus name)|uniprotkb:YBR2016(orf name)|uniprotkb:Protein PAF1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Squazzo et al. (2002) pubmed:11927560|imex:IM-19478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2436778|imex:IM-19478-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001160"(regulation of histone H3-K79 methylation)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR004343(Plus-3)|interpro:IPR036128|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|rcsb pdb:5E8B|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0042138"(meiotic DNA double-strand break formation)|rcsb pdb:5EMX|ensemblfungi:YGL244W(gene)|ensemblfungi:YGL244W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_011270.1|sgd:S000003213|dip:DIP-4065N|mint:P53064 ensemblfungi:YBR279W(gene)|ensemblfungi:YBR279W_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006364"(rRNA processing)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_009838.1|sgd:S000000483|mint:P38351|dip:DIP-1149N - crc64:13AECCEC6D63CED4 - figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/18 2014/10/16 rogid:jPawNxTgh9wPA5Uxbn5QCUeDw9Q559292 rogid:k4kVCyYuA4w4+4OEroTkwhbxs6Q559292 intact-crc:66C78094EB1E2895|rigid:iyQChulXg9mWQohRg0OJlckkIVE false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53064 uniprotkb:Q06697 intact:EBI-16303|uniprotkb:P89115|ensemblfungi:YGL244W|uniprotkb:D6VV91 intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C psi-mi:rtf1_yeast(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:YGL244W(locus name)|uniprotkb:HRA458(orf name)|uniprotkb:CSL3(gene name synonym) psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:"MI:0676"(tandem affinity purification) Squazzo et al. (2002) pubmed:11927560|imex:IM-19478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2436778|imex:IM-19478-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001160"(regulation of histone H3-K79 methylation)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR004343(Plus-3)|interpro:IPR036128|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|rcsb pdb:5E8B|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0042138"(meiotic DNA double-strand break formation)|rcsb pdb:5EMX|ensemblfungi:YGL244W(gene)|ensemblfungi:YGL244W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_011270.1|sgd:S000003213|dip:DIP-4065N|mint:P53064 refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955 - crc64:13AECCEC6D63CED4 crc64:9580B53EEFB75345 figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/18 2014/10/16 rogid:jPawNxTgh9wPA5Uxbn5QCUeDw9Q559292 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 intact-crc:66C78094EB1E2895|rigid:iyQChulXg9mWQohRg0OJlckkIVE false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53064 uniprotkb:P38439 intact:EBI-16303|uniprotkb:P89115|ensemblfungi:YGL244W|uniprotkb:D6VV91 intact:EBI-10108|uniprotkb:D6W2I1|ensemblfungi:YOR123C psi-mi:rtf1_yeast(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:YGL244W(locus name)|uniprotkb:HRA458(orf name)|uniprotkb:CSL3(gene name synonym) psi-mi:leo1_yeast(display_long)|uniprotkb:O3278(orf name)|uniprotkb:YOR3278C(orf name)|uniprotkb:YOR123C(locus name)|uniprotkb:LEO1(gene name)|psi-mi:LEO1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Squazzo et al. (2002) pubmed:11927560|imex:IM-19478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2436794|imex:IM-19478-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001160"(regulation of histone H3-K79 methylation)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR004343(Plus-3)|interpro:IPR036128|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|rcsb pdb:5E8B|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0042138"(meiotic DNA double-strand break formation)|rcsb pdb:5EMX|ensemblfungi:YGL244W(gene)|ensemblfungi:YGL244W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_011270.1|sgd:S000003213|dip:DIP-4065N|mint:P53064 refseq:NP_014766.1|sgd:S000005649|ensemblfungi:YOR123C(gene)|ensemblfungi:YOR123C_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0006325"(chromatin organization)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR007149(Leo1-like protein)|go:"GO:0005634"(nucleus)|reactome:R-SCE-674695|reactome:R-SCE-75955|dip:DIP-4143N|mint:P38439 - crc64:13AECCEC6D63CED4 crc64:ABDE3D7D5A2C78A5 figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/18 2014/10/16 rogid:jPawNxTgh9wPA5Uxbn5QCUeDw9Q559292 rogid:qhB5pVP3l4WqXtp3JhmPsxEVHE0559292 intact-crc:26444901BCD1C147|rigid:8SYy8rcEwud0mPk5r8wV2J98gEw false - ha tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53064 uniprotkb:P38351 intact:EBI-16303|uniprotkb:P89115|ensemblfungi:YGL244W|uniprotkb:D6VV91 intact:EBI-12855|uniprotkb:Q9URC9|uniprotkb:D6VQS4|ensemblfungi:YBR279W psi-mi:rtf1_yeast(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:YGL244W(locus name)|uniprotkb:HRA458(orf name)|uniprotkb:CSL3(gene name synonym) psi-mi:paf1_yeast(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:YBR279W(locus name)|uniprotkb:YBR2016(orf name)|uniprotkb:Protein PAF1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Squazzo et al. (2002) pubmed:11927560|imex:IM-19478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2436801|imex:IM-19478-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001160"(regulation of histone H3-K79 methylation)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR004343(Plus-3)|interpro:IPR036128|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|rcsb pdb:5E8B|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0042138"(meiotic DNA double-strand break formation)|rcsb pdb:5EMX|ensemblfungi:YGL244W(gene)|ensemblfungi:YGL244W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_011270.1|sgd:S000003213|dip:DIP-4065N|mint:P53064 ensemblfungi:YBR279W(gene)|ensemblfungi:YBR279W_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006364"(rRNA processing)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_009838.1|sgd:S000000483|mint:P38351|dip:DIP-1149N - crc64:13AECCEC6D63CED4 - figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/18 2014/10/16 rogid:jPawNxTgh9wPA5Uxbn5QCUeDw9Q559292 rogid:k4kVCyYuA4w4+4OEroTkwhbxs6Q559292 intact-crc:2CF09EC0910C37C7|rigid:dKavp1gKbYJRsRvSTuHxtnLPVlA false - ha tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53064 uniprotkb:P89105 intact:EBI-16303|uniprotkb:P89115|ensemblfungi:YGL244W|uniprotkb:D6VV91 intact:EBI-5283|uniprotkb:O14409|uniprotkb:Q07332|uniprotkb:Q08292|uniprotkb:D6W1S4|ensemblfungi:YOL145C psi-mi:rtf1_yeast(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:YGL244W(locus name)|uniprotkb:HRA458(orf name)|uniprotkb:CSL3(gene name synonym) psi-mi:ctr9_yeast(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:CDP1(gene name synonym)|uniprotkb:Cln three-requiring protein 9(gene name synonym)|uniprotkb:Centromere-binding factor 1-dependent protein 1(gene name synonym)|uniprotkb:YOL145C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Squazzo et al. (2002) pubmed:11927560|imex:IM-19478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2461288|imex:IM-19478-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001160"(regulation of histone H3-K79 methylation)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR004343(Plus-3)|interpro:IPR036128|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|rcsb pdb:5E8B|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0042138"(meiotic DNA double-strand break formation)|rcsb pdb:5EMX|ensemblfungi:YGL244W(gene)|ensemblfungi:YGL244W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_011270.1|sgd:S000003213|dip:DIP-4065N|mint:P53064 refseq:NP_014496.2|sgd:S000005505|dip:DIP-2814N|mint:P89105|ensemblfungi:YOL145C(gene)|ensemblfungi:YOL145C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0035327"|go:"GO:0045142"(triplex DNA binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955 - crc64:13AECCEC6D63CED4 crc64:F794ECBAD26D4820 figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/18 2014/10/16 rogid:jPawNxTgh9wPA5Uxbn5QCUeDw9Q559292 rogid:85qAqldtQL8T7JBgNxrvAYtHhd0559292 intact-crc:CEE4F5F96E7CEA3C|rigid:4EUyULCPTZdH7UTTjLienlNjn2M false - myc tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P38439 uniprotkb:Q04636 intact:EBI-10108|uniprotkb:D6W2I1|ensemblfungi:YOR123C intact:EBI-27863|uniprotkb:D6VZA4|ensemblfungi:YML069W psi-mi:leo1_yeast(display_long)|uniprotkb:O3278(orf name)|uniprotkb:YOR3278C(orf name)|uniprotkb:YOR123C(locus name)|uniprotkb:LEO1(gene name)|psi-mi:LEO1(display_short) psi-mi:pob3_yeast(display_long)|uniprotkb:YML069W(locus name)|uniprotkb:Facilitates chromatin transcription complex subunit POB3(gene name synonym)|uniprotkb:POB3(gene name)|psi-mi:POB3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Squazzo et al. (2002) pubmed:11927560|imex:IM-19478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2461316|imex:IM-19478-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014766.1|sgd:S000005649|ensemblfungi:YOR123C(gene)|ensemblfungi:YOR123C_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0006325"(chromatin organization)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR007149(Leo1-like protein)|go:"GO:0005634"(nucleus)|reactome:R-SCE-674695|reactome:R-SCE-75955|dip:DIP-4143N|mint:P38439 refseq:NP_013642.1|sgd:S000004534|dip:DIP-4083N|mint:Q04636|ensemblfungi:YML069W(gene)|ensemblfungi:YML069W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR000969(Structure-specific recognition protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR024954|interpro:IPR035417|interpro:IPR038167|rcsb pdb:2GCJ|rcsb pdb:2GCL|rcsb pdb:3F5R|rcsb pdb:4PQ0|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6804756|reactome:R-SCE-75955|go:"GO:0031298"(replication fork protection complex) - crc64:ABDE3D7D5A2C78A5 crc64:02C04F620C7B1450 figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/18 2014/10/16 rogid:qhB5pVP3l4WqXtp3JhmPsxEVHE0559292 rogid:P1VkOQ4LPSsxfSZaDykpvS9FRPU559292 intact-crc:C3216982ABE9E8C7|rigid:/AIu61tLhp8DAhs5vFv9riTtipw false ha tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P38439 uniprotkb:P27692 intact:EBI-10108|uniprotkb:D6W2I1|ensemblfungi:YOR123C intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W psi-mi:leo1_yeast(display_long)|uniprotkb:O3278(orf name)|uniprotkb:YOR3278C(orf name)|uniprotkb:YOR123C(locus name)|uniprotkb:LEO1(gene name)|psi-mi:LEO1(display_short) psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Squazzo et al. (2002) pubmed:11927560|imex:IM-19478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2461316|imex:IM-19478-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014766.1|sgd:S000005649|ensemblfungi:YOR123C(gene)|ensemblfungi:YOR123C_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0006325"(chromatin organization)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR007149(Leo1-like protein)|go:"GO:0005634"(nucleus)|reactome:R-SCE-674695|reactome:R-SCE-75955|dip:DIP-4143N|mint:P38439 refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692 - crc64:ABDE3D7D5A2C78A5 crc64:E4324DB6B1E4721A figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/18 2014/10/16 rogid:qhB5pVP3l4WqXtp3JhmPsxEVHE0559292 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 intact-crc:C3216982ABE9E8C7|rigid:/AIu61tLhp8DAhs5vFv9riTtipw false ha tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P38439 uniprotkb:P32558 intact:EBI-10108|uniprotkb:D6W2I1|ensemblfungi:YOR123C intact:EBI-4334|ensemblfungi:YGL207W|uniprotkb:D6VTU8 psi-mi:leo1_yeast(display_long)|uniprotkb:O3278(orf name)|uniprotkb:YOR3278C(orf name)|uniprotkb:YOR123C(locus name)|uniprotkb:LEO1(gene name)|psi-mi:LEO1(display_short) psi-mi:spt16_yeast(display_long)|uniprotkb:SPT16(gene name)|psi-mi:SPT16(display_short)|uniprotkb:CDC68(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:YGL207W(locus name)|uniprotkb:Facilitates chromatin transcription complex subunit SPT16(gene name synonym)|uniprotkb:Suppressor of Ty protein 16(gene name synonym)|uniprotkb:Cell division control protein 68(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Squazzo et al. (2002) pubmed:11927560|imex:IM-19478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2461316|imex:IM-19478-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014766.1|sgd:S000005649|ensemblfungi:YOR123C(gene)|ensemblfungi:YOR123C_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0006325"(chromatin organization)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR007149(Leo1-like protein)|go:"GO:0005634"(nucleus)|reactome:R-SCE-674695|reactome:R-SCE-75955|dip:DIP-4143N|mint:P38439 dip:DIP-2546N|ensemblfungi:YGL207W(gene)|ensemblfungi:YGL207W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007063"(regulation of sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011308.1|sgd:S000003175|mint:P32558|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR013953(FACT complex subunit Spt16p/Cdc68p)|interpro:IPR029148|interpro:IPR029149|interpro:IPR033825|interpro:IPR036005|interpro:IPR040258|rcsb pdb:3BIP|rcsb pdb:3BIQ|rcsb pdb:3BIT|rcsb pdb:4IOY|rcsb pdb:4WNN|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6804756|reactome:R-SCE-75955 - crc64:ABDE3D7D5A2C78A5 crc64:4F01C772E299E2E6 figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/18 2014/10/16 rogid:qhB5pVP3l4WqXtp3JhmPsxEVHE0559292 rogid:BjmFZfhrj4mp5mz0vNNG1JS4Hrk559292 intact-crc:C3216982ABE9E8C7|rigid:/AIu61tLhp8DAhs5vFv9riTtipw false ha tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P89105 uniprotkb:P27692 intact:EBI-5283|uniprotkb:O14409|uniprotkb:Q07332|uniprotkb:Q08292|uniprotkb:D6W1S4|ensemblfungi:YOL145C intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W psi-mi:ctr9_yeast(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:CDP1(gene name synonym)|uniprotkb:Cln three-requiring protein 9(gene name synonym)|uniprotkb:Centromere-binding factor 1-dependent protein 1(gene name synonym)|uniprotkb:YOL145C(locus name) psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Squazzo et al. (2002) pubmed:11927560|imex:IM-19478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2461324|imex:IM-19478-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014496.2|sgd:S000005505|dip:DIP-2814N|mint:P89105|ensemblfungi:YOL145C(gene)|ensemblfungi:YOL145C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0035327"|go:"GO:0045142"(triplex DNA binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955 refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692 - crc64:F794ECBAD26D4820 crc64:E4324DB6B1E4721A figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/18 2014/10/16 rogid:85qAqldtQL8T7JBgNxrvAYtHhd0559292 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 intact-crc:5DB98F68504FE234|rigid:wmSssMpbt8HJTPvUtTD70lJGsUs false myc tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P89105 uniprotkb:P53064 intact:EBI-5283|uniprotkb:O14409|uniprotkb:Q07332|uniprotkb:Q08292|uniprotkb:D6W1S4|ensemblfungi:YOL145C intact:EBI-16303|uniprotkb:P89115|ensemblfungi:YGL244W|uniprotkb:D6VV91 psi-mi:ctr9_yeast(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:CDP1(gene name synonym)|uniprotkb:Cln three-requiring protein 9(gene name synonym)|uniprotkb:Centromere-binding factor 1-dependent protein 1(gene name synonym)|uniprotkb:YOL145C(locus name) psi-mi:rtf1_yeast(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:YGL244W(locus name)|uniprotkb:HRA458(orf name)|uniprotkb:CSL3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Squazzo et al. (2002) pubmed:11927560|imex:IM-19478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2461324|imex:IM-19478-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014496.2|sgd:S000005505|dip:DIP-2814N|mint:P89105|ensemblfungi:YOL145C(gene)|ensemblfungi:YOL145C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0035327"|go:"GO:0045142"(triplex DNA binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955 go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001160"(regulation of histone H3-K79 methylation)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR004343(Plus-3)|interpro:IPR036128|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|rcsb pdb:5E8B|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0042138"(meiotic DNA double-strand break formation)|rcsb pdb:5EMX|ensemblfungi:YGL244W(gene)|ensemblfungi:YGL244W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_011270.1|sgd:S000003213|dip:DIP-4065N|mint:P53064 - crc64:F794ECBAD26D4820 crc64:13AECCEC6D63CED4 figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/18 2014/10/16 rogid:85qAqldtQL8T7JBgNxrvAYtHhd0559292 rogid:jPawNxTgh9wPA5Uxbn5QCUeDw9Q559292 intact-crc:5DB98F68504FE234|rigid:wmSssMpbt8HJTPvUtTD70lJGsUs false myc tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P38351 uniprotkb:P27692 intact:EBI-12855|uniprotkb:Q9URC9|uniprotkb:D6VQS4|ensemblfungi:YBR279W intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W psi-mi:paf1_yeast(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:YBR279W(locus name)|uniprotkb:YBR2016(orf name)|uniprotkb:Protein PAF1(gene name synonym) psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Squazzo et al. (2002) pubmed:11927560|imex:IM-19478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2461333|imex:IM-19478-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBR279W(gene)|ensemblfungi:YBR279W_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006364"(rRNA processing)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_009838.1|sgd:S000000483|mint:P38351|dip:DIP-1149N refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692 - - crc64:E4324DB6B1E4721A figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/18 2014/10/16 rogid:k4kVCyYuA4w4+4OEroTkwhbxs6Q559292 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 intact-crc:C3228E0FD49CDC90|rigid:dVNpMk4hEUo/bN8jIx+GpYnVK7A false ha tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P38351 uniprotkb:P32558 intact:EBI-12855|uniprotkb:Q9URC9|uniprotkb:D6VQS4|ensemblfungi:YBR279W intact:EBI-4334|ensemblfungi:YGL207W|uniprotkb:D6VTU8 psi-mi:paf1_yeast(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:YBR279W(locus name)|uniprotkb:YBR2016(orf name)|uniprotkb:Protein PAF1(gene name synonym) psi-mi:spt16_yeast(display_long)|uniprotkb:SPT16(gene name)|psi-mi:SPT16(display_short)|uniprotkb:CDC68(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:YGL207W(locus name)|uniprotkb:Facilitates chromatin transcription complex subunit SPT16(gene name synonym)|uniprotkb:Suppressor of Ty protein 16(gene name synonym)|uniprotkb:Cell division control protein 68(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Squazzo et al. (2002) pubmed:11927560|imex:IM-19478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2461333|imex:IM-19478-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBR279W(gene)|ensemblfungi:YBR279W_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006364"(rRNA processing)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_009838.1|sgd:S000000483|mint:P38351|dip:DIP-1149N dip:DIP-2546N|ensemblfungi:YGL207W(gene)|ensemblfungi:YGL207W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007063"(regulation of sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011308.1|sgd:S000003175|mint:P32558|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR013953(FACT complex subunit Spt16p/Cdc68p)|interpro:IPR029148|interpro:IPR029149|interpro:IPR033825|interpro:IPR036005|interpro:IPR040258|rcsb pdb:3BIP|rcsb pdb:3BIQ|rcsb pdb:3BIT|rcsb pdb:4IOY|rcsb pdb:4WNN|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6804756|reactome:R-SCE-75955 - - crc64:4F01C772E299E2E6 figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/18 2014/10/16 rogid:k4kVCyYuA4w4+4OEroTkwhbxs6Q559292 rogid:BjmFZfhrj4mp5mz0vNNG1JS4Hrk559292 intact-crc:C3228E0FD49CDC90|rigid:dVNpMk4hEUo/bN8jIx+GpYnVK7A false ha tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P38351 uniprotkb:Q04636 intact:EBI-12855|uniprotkb:Q9URC9|uniprotkb:D6VQS4|ensemblfungi:YBR279W intact:EBI-27863|uniprotkb:D6VZA4|ensemblfungi:YML069W psi-mi:paf1_yeast(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:YBR279W(locus name)|uniprotkb:YBR2016(orf name)|uniprotkb:Protein PAF1(gene name synonym) psi-mi:pob3_yeast(display_long)|uniprotkb:YML069W(locus name)|uniprotkb:Facilitates chromatin transcription complex subunit POB3(gene name synonym)|uniprotkb:POB3(gene name)|psi-mi:POB3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Squazzo et al. (2002) pubmed:11927560|imex:IM-19478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2461333|imex:IM-19478-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBR279W(gene)|ensemblfungi:YBR279W_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006364"(rRNA processing)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_009838.1|sgd:S000000483|mint:P38351|dip:DIP-1149N refseq:NP_013642.1|sgd:S000004534|dip:DIP-4083N|mint:Q04636|ensemblfungi:YML069W(gene)|ensemblfungi:YML069W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR000969(Structure-specific recognition protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR024954|interpro:IPR035417|interpro:IPR038167|rcsb pdb:2GCJ|rcsb pdb:2GCL|rcsb pdb:3F5R|rcsb pdb:4PQ0|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6804756|reactome:R-SCE-75955|go:"GO:0031298"(replication fork protection complex) - - crc64:02C04F620C7B1450 figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/18 2014/10/16 rogid:k4kVCyYuA4w4+4OEroTkwhbxs6Q559292 rogid:P1VkOQ4LPSsxfSZaDykpvS9FRPU559292 intact-crc:C3228E0FD49CDC90|rigid:dVNpMk4hEUo/bN8jIx+GpYnVK7A false ha tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P89105 uniprotkb:P38439 intact:EBI-5283|uniprotkb:O14409|uniprotkb:Q07332|uniprotkb:Q08292|uniprotkb:D6W1S4|ensemblfungi:YOL145C intact:EBI-10108|uniprotkb:D6W2I1|ensemblfungi:YOR123C psi-mi:ctr9_yeast(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:CDP1(gene name synonym)|uniprotkb:Cln three-requiring protein 9(gene name synonym)|uniprotkb:Centromere-binding factor 1-dependent protein 1(gene name synonym)|uniprotkb:YOL145C(locus name) psi-mi:leo1_yeast(display_long)|uniprotkb:O3278(orf name)|uniprotkb:YOR3278C(orf name)|uniprotkb:YOR123C(locus name)|uniprotkb:LEO1(gene name)|psi-mi:LEO1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Squazzo et al. (2002) pubmed:11927560|imex:IM-19478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2461277|imex:IM-19478-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014496.2|sgd:S000005505|dip:DIP-2814N|mint:P89105|ensemblfungi:YOL145C(gene)|ensemblfungi:YOL145C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0035327"|go:"GO:0045142"(triplex DNA binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955 refseq:NP_014766.1|sgd:S000005649|ensemblfungi:YOR123C(gene)|ensemblfungi:YOR123C_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0006325"(chromatin organization)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR007149(Leo1-like protein)|go:"GO:0005634"(nucleus)|reactome:R-SCE-674695|reactome:R-SCE-75955|dip:DIP-4143N|mint:P38439 - crc64:F794ECBAD26D4820 crc64:ABDE3D7D5A2C78A5 figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/18 2014/10/16 rogid:85qAqldtQL8T7JBgNxrvAYtHhd0559292 rogid:qhB5pVP3l4WqXtp3JhmPsxEVHE0559292 intact-crc:216999609E1D8FD2|rigid:pU68zunNOnYTI6d2hWoIoxqEJhk false myc tag:c-c ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P89105 uniprotkb:P38439 intact:EBI-5283|uniprotkb:O14409|uniprotkb:Q07332|uniprotkb:Q08292|uniprotkb:D6W1S4|ensemblfungi:YOL145C intact:EBI-10108|uniprotkb:D6W2I1|ensemblfungi:YOR123C psi-mi:ctr9_yeast(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:CDP1(gene name synonym)|uniprotkb:Cln three-requiring protein 9(gene name synonym)|uniprotkb:Centromere-binding factor 1-dependent protein 1(gene name synonym)|uniprotkb:YOL145C(locus name) psi-mi:leo1_yeast(display_long)|uniprotkb:O3278(orf name)|uniprotkb:YOR3278C(orf name)|uniprotkb:YOR123C(locus name)|uniprotkb:LEO1(gene name)|psi-mi:LEO1(display_short) psi-mi:"MI:0071"(molecular sieving) Squazzo et al. (2002) pubmed:11927560|imex:IM-19478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2461305|imex:IM-19478-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014496.2|sgd:S000005505|dip:DIP-2814N|mint:P89105|ensemblfungi:YOL145C(gene)|ensemblfungi:YOL145C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0035327"|go:"GO:0045142"(triplex DNA binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955 refseq:NP_014766.1|sgd:S000005649|ensemblfungi:YOR123C(gene)|ensemblfungi:YOR123C_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0006325"(chromatin organization)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR007149(Leo1-like protein)|go:"GO:0005634"(nucleus)|reactome:R-SCE-674695|reactome:R-SCE-75955|dip:DIP-4143N|mint:P38439 - crc64:F794ECBAD26D4820 crc64:ABDE3D7D5A2C78A5 figure legend:Fig. 2D|complex-properties:Complex weight approximately 670kDa|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/18 2014/10/16 rogid:85qAqldtQL8T7JBgNxrvAYtHhd0559292 rogid:qhB5pVP3l4WqXtp3JhmPsxEVHE0559292 intact-crc:F19E55CCBB93895F|rigid:teaMSsKBACxaARM8JCLzfB4NRHo false myc tag:c-c ha tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P89105 uniprotkb:P53064 intact:EBI-5283|uniprotkb:O14409|uniprotkb:Q07332|uniprotkb:Q08292|uniprotkb:D6W1S4|ensemblfungi:YOL145C intact:EBI-16303|uniprotkb:P89115|ensemblfungi:YGL244W|uniprotkb:D6VV91 psi-mi:ctr9_yeast(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:CDP1(gene name synonym)|uniprotkb:Cln three-requiring protein 9(gene name synonym)|uniprotkb:Centromere-binding factor 1-dependent protein 1(gene name synonym)|uniprotkb:YOL145C(locus name) psi-mi:rtf1_yeast(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:YGL244W(locus name)|uniprotkb:HRA458(orf name)|uniprotkb:CSL3(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Squazzo et al. (2002) pubmed:11927560|imex:IM-19478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2461305|imex:IM-19478-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014496.2|sgd:S000005505|dip:DIP-2814N|mint:P89105|ensemblfungi:YOL145C(gene)|ensemblfungi:YOL145C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0035327"|go:"GO:0045142"(triplex DNA binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955 go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001160"(regulation of histone H3-K79 methylation)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR004343(Plus-3)|interpro:IPR036128|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|rcsb pdb:5E8B|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0042138"(meiotic DNA double-strand break formation)|rcsb pdb:5EMX|ensemblfungi:YGL244W(gene)|ensemblfungi:YGL244W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_011270.1|sgd:S000003213|dip:DIP-4065N|mint:P53064 - crc64:F794ECBAD26D4820 crc64:13AECCEC6D63CED4 figure legend:Fig. 2D|complex-properties:Complex weight approximately 670kDa|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/18 2014/10/16 rogid:85qAqldtQL8T7JBgNxrvAYtHhd0559292 rogid:jPawNxTgh9wPA5Uxbn5QCUeDw9Q559292 intact-crc:F19E55CCBB93895F|rigid:teaMSsKBACxaARM8JCLzfB4NRHo false myc tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53064 uniprotkb:P04050 intact:EBI-16303|uniprotkb:P89115|ensemblfungi:YGL244W|uniprotkb:D6VV91 intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C psi-mi:rtf1_yeast(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:YGL244W(locus name)|uniprotkb:HRA458(orf name)|uniprotkb:CSL3(gene name synonym) psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Squazzo et al. (2002) pubmed:11927560|imex:IM-19478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2461349|imex:IM-19478-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001160"(regulation of histone H3-K79 methylation)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR004343(Plus-3)|interpro:IPR036128|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|rcsb pdb:5E8B|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0042138"(meiotic DNA double-strand break formation)|rcsb pdb:5EMX|ensemblfungi:YGL244W(gene)|ensemblfungi:YGL244W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_011270.1|sgd:S000003213|dip:DIP-4065N|mint:P53064 refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519 - crc64:13AECCEC6D63CED4 crc64:A45C1360FF99F968 figure legend:Fig. 6C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/18 2014/10/16 rogid:jPawNxTgh9wPA5Uxbn5QCUeDw9Q559292 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 intact-crc:78A6D1E7DD4A9A5D|rigid:2WpwK9vbEL+BJJUKC6XC8Qi7FKk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53064 uniprotkb:P27692 intact:EBI-16303|uniprotkb:P89115|ensemblfungi:YGL244W|uniprotkb:D6VV91 intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W psi-mi:rtf1_yeast(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:YGL244W(locus name)|uniprotkb:HRA458(orf name)|uniprotkb:CSL3(gene name synonym) psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Squazzo et al. (2002) pubmed:11927560|imex:IM-19478 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2461349|imex:IM-19478-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001160"(regulation of histone H3-K79 methylation)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR004343(Plus-3)|interpro:IPR036128|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|rcsb pdb:5E8B|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0042138"(meiotic DNA double-strand break formation)|rcsb pdb:5EMX|ensemblfungi:YGL244W(gene)|ensemblfungi:YGL244W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_011270.1|sgd:S000003213|dip:DIP-4065N|mint:P53064 refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692 - crc64:13AECCEC6D63CED4 crc64:E4324DB6B1E4721A figure legend:Fig. 6C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/18 2014/10/16 rogid:jPawNxTgh9wPA5Uxbn5QCUeDw9Q559292 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 intact-crc:78A6D1E7DD4A9A5D|rigid:2WpwK9vbEL+BJJUKC6XC8Qi7FKk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)