#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B chebi:"CHEBI:15996" uniprotkb:P32769 intact:EBI-989053|chebi:"CHEBI:42934"|chebi:"CHEBI:5234"|chebi:"CHEBI:13342"|chebi:"CHEBI:24451" intact:EBI-8194|uniprotkb:D6VXE4|ensemblfungi:YKR084C psi-mi:gtp(display_short)|psi-mi:"CHEBI:15996"(display_long)|intact:5'-GTP(synonym)|intact:GTP(synonym)|intact:Guanosine 5'-triphosphate(synonym)|intact:guanosine 5'-triphosphoric acid(synonym)|intact:guanosine triphosphate(synonym)|intact:GUANOSINE-5'-TRIPHOSPHATE(synonym)|intact:H4gtp(synonym)|intact:"guanosine 5'-(tetrahydrogen triphosphate)"(iupac name) psi-mi:hbs1_yeast(display_long)|uniprotkb:HBS1(gene name)|psi-mi:HBS1(display_short)|uniprotkb:YKR404(orf name)|uniprotkb:YKR084C(locus name) psi-mi:"MI:0030"(cross-linking study) Carr-Schmid et al. (2002) pubmed:11909951|imex:IM-20249 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2215460|imex:IM-20249-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - sgd:S000001792|refseq:NP_013010.3|dip:DIP-762N|ensemblfungi:YKR084C(gene)|ensemblfungi:YKR084C_mRNA(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0032790"(ribosome disassembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:1990533"(Dom34-Hbs1 complex)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015033(Region of unknown function DUF1916)|interpro:IPR027417|interpro:IPR031157|rcsb pdb:3IZQ|rcsb pdb:3P26|rcsb pdb:3P27|rcsb pdb:5M1J|reactome:R-SCE-429958 - author-identifiers:"InChI=1/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1/f/h14,19-20,22,24H,11H2" crc64:11EC2CB6936396EE comment:GTP was 32P-tagged|figure legend:Figure 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/02/04 2016/08/15 - rogid:8WhkbGcgKAw41+dB1sOeeew1RJY559292 intact-crc:5E1862F0728B35CF false - glutathione s tranferase tag:n-n - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P33309 uniprotkb:P32769 intact:EBI-6012|uniprotkb:D6W1H6|ensemblfungi:YNL001W intact:EBI-8194|uniprotkb:D6VXE4|ensemblfungi:YKR084C psi-mi:dom34_yeast(display_long)|uniprotkb:N2016(orf name)|uniprotkb:YNL001W(locus name)|uniprotkb:DOM34(gene name)|psi-mi:DOM34(display_short) psi-mi:hbs1_yeast(display_long)|uniprotkb:HBS1(gene name)|psi-mi:HBS1(display_short)|uniprotkb:YKR404(orf name)|uniprotkb:YKR084C(locus name) psi-mi:"MI:0018"(two hybrid) Carr-Schmid et al. (2002) pubmed:11909951|imex:IM-20249 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2215483|imex:IM-20249-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014397.1|sgd:S000004946|dip:DIP-7520N|ensemblfungi:YNL001W(gene)|ensemblfungi:YNL001W_mRNA(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0032790"(ribosome disassembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:0071025"(RNA surveillance)|go:"GO:1990533"(Dom34-Hbs1 complex)|interpro:IPR004405(Probable translation factor pelota)|interpro:IPR005140(eRF1 domain 1)|interpro:IPR005141(eRF1 domain 2)|interpro:IPR005142(eRF1 domain 3)|interpro:IPR029064|interpro:IPR038069|interpro:IPR042226|rcsb pdb:2VGM|rcsb pdb:2VGN|rcsb pdb:3IZQ|rcsb pdb:3J16|rcsb pdb:5M1J sgd:S000001792|refseq:NP_013010.3|dip:DIP-762N|ensemblfungi:YKR084C(gene)|ensemblfungi:YKR084C_mRNA(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0032790"(ribosome disassembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:1990533"(Dom34-Hbs1 complex)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015033(Region of unknown function DUF1916)|interpro:IPR027417|interpro:IPR031157|rcsb pdb:3IZQ|rcsb pdb:3P26|rcsb pdb:3P27|rcsb pdb:5M1J|reactome:R-SCE-429958 - crc64:4E8B7D9BBCD60888 crc64:11EC2CB6936396EE figure legend:Figure 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/02/04 2014/10/16 rogid:AjrNfKo6LoskZXKNyN+4qXBZEUQ559292 rogid:8WhkbGcgKAw41+dB1sOeeew1RJY559292 intact-crc:58B9EDABA945AD72|rigid:uGtcFGquKxfKlJAHkr1b05v0MeE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06782 uniprotkb:P12904 intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W intact:EBI-17537|ensemblfungi:YGL115W|uniprotkb:D6VU32 psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name) psi-mi:aakg_yeast(display_long)|uniprotkb:SNF4(gene name)|psi-mi:SNF4(display_short)|uniprotkb:CAT3(gene name synonym)|uniprotkb:Regulatory protein CAT3(gene name synonym)|uniprotkb:SCI1(gene name synonym)|uniprotkb:Sucrose non-fermenting protein 4(gene name synonym)|uniprotkb:YGL115W(locus name) psi-mi:"MI:0018"(two hybrid) Carr-Schmid et al. (2002) pubmed:11909951|imex:IM-20249 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2215512|imex:IM-20249-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782 go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|ensemblfungi:YGL115W(gene)|ensemblfungi:YGL115W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|refseq:NP_011400.1|sgd:S000003083|go:"GO:0007031"(peroxisome organization)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000644(Cystathionine beta-synthase, core)|rcsb pdb:2NYC|rcsb pdb:2NYE|rcsb pdb:2QLV|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|dip:DIP-592N|mint:P12904 - crc64:F5C63565C986C4E3 crc64:51B387E346EE9561 figure legend:Figure 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/02/04 2014/10/16 rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292 rogid:dYtx5LQZtt2QZX/VelN4akMH7KA559292 intact-crc:9ECCAA73CA269CFD|rigid:4MHnCvJEe/pauqdj+JsPSZ8Bj+o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33309 uniprotkb:P32769 intact:EBI-6012|uniprotkb:D6W1H6|ensemblfungi:YNL001W intact:EBI-8194|uniprotkb:D6VXE4|ensemblfungi:YKR084C psi-mi:dom34_yeast(display_long)|uniprotkb:N2016(orf name)|uniprotkb:YNL001W(locus name)|uniprotkb:DOM34(gene name)|psi-mi:DOM34(display_short) psi-mi:hbs1_yeast(display_long)|uniprotkb:HBS1(gene name)|psi-mi:HBS1(display_short)|uniprotkb:YKR404(orf name)|uniprotkb:YKR084C(locus name) psi-mi:"MI:0096"(pull down) Carr-Schmid et al. (2002) pubmed:11909951|imex:IM-20249 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2215556|imex:IM-20249-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014397.1|sgd:S000004946|dip:DIP-7520N|ensemblfungi:YNL001W(gene)|ensemblfungi:YNL001W_mRNA(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0032790"(ribosome disassembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:0071025"(RNA surveillance)|go:"GO:1990533"(Dom34-Hbs1 complex)|interpro:IPR004405(Probable translation factor pelota)|interpro:IPR005140(eRF1 domain 1)|interpro:IPR005141(eRF1 domain 2)|interpro:IPR005142(eRF1 domain 3)|interpro:IPR029064|interpro:IPR038069|interpro:IPR042226|rcsb pdb:2VGM|rcsb pdb:2VGN|rcsb pdb:3IZQ|rcsb pdb:3J16|rcsb pdb:5M1J sgd:S000001792|refseq:NP_013010.3|dip:DIP-762N|ensemblfungi:YKR084C(gene)|ensemblfungi:YKR084C_mRNA(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0032790"(ribosome disassembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:1990533"(Dom34-Hbs1 complex)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015033(Region of unknown function DUF1916)|interpro:IPR027417|interpro:IPR031157|rcsb pdb:3IZQ|rcsb pdb:3P26|rcsb pdb:3P27|rcsb pdb:5M1J|reactome:R-SCE-429958 - crc64:4E8B7D9BBCD60888 crc64:11EC2CB6936396EE figure legend:Figure 4b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/02/04 2014/10/16 rogid:AjrNfKo6LoskZXKNyN+4qXBZEUQ559292 rogid:8WhkbGcgKAw41+dB1sOeeew1RJY559292 intact-crc:CB839508BCAE6FAC|rigid:uGtcFGquKxfKlJAHkr1b05v0MeE false ha tag:?-? glutathione s tranferase tag:n-n|sufficient binding region:162-611 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)