#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q08965	uniprotkb:Q08096	intact:EBI-3683|uniprotkb:D6W3F3|ensemblfungi:YPL217C	intact:EBI-14892|uniprotkb:D6W257|ensemblfungi:YOL010W	psi-mi:bms1_yeast(display_long)|uniprotkb:YPL217C(locus name)|uniprotkb:BMS1(gene name)|psi-mi:BMS1(display_short)	psi-mi:rcl1_yeast(display_long)|uniprotkb:RCL1(gene name)|psi-mi:RCL1(display_short)|uniprotkb:RTC1(gene name synonym)|uniprotkb:YOL010W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wegierski et al. (2001)	pubmed:11565748|imex:IM-19201	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2275179|imex:IM-19201-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015107.1|sgd:S000006138|dip:DIP-6562N|mint:Q08965|ensemblfungi:YPL217C(gene)|ensemblfungi:YPL217C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000479"("endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0030686"(90S preribosome)|go:"GO:0034511"(U3 snoRNA binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR007034(Protein of unknown function DUF663)|interpro:IPR012948(AARP2CN)|interpro:IPR027417|interpro:IPR030387|interpro:IPR037875|interpro:IPR039761|rcsb pdb:4CLQ|rcsb pdb:5JPQ|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226	refseq:NP_014633.1|sgd:S000005370|go:"GO:0000479"("endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030686"(90S preribosome)|interpro:IPR000228(RNA 3'-terminal phosphate cyclase)|interpro:IPR013791(RNA 3'-terminal phosphate cyclase, subset, insert region)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR016443(RNA 3'-terminal phosphate cyclase-like, eukaryotic)|interpro:IPR020719|interpro:IPR023797|interpro:IPR036553|interpro:IPR037136|rcsb pdb:4CLQ|rcsb pdb:5JPQ|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|ensemblfungi:YOL010W(gene)|ensemblfungi:YOL010W_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|dip:DIP-4539N|mint:Q08096	-	crc64:9A337F1EE0B0F21D	crc64:C5DDA7F9B0C1E296	figure legend:Figure 1a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/03/13	2014/10/16	rogid:wG8wlE3l3G1E7VJiO/epPEDxTOE559292	rogid:wYe82ZA+YhfdftbYKX8+GBxQojo559292	intact-crc:E197B2792869C49C|rigid:ZXyAyPFAEtKNWbMhy2RIgoy7WKM	false	protein a tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q08965	uniprotkb:Q08096	intact:EBI-3683|uniprotkb:D6W3F3|ensemblfungi:YPL217C	intact:EBI-14892|uniprotkb:D6W257|ensemblfungi:YOL010W	psi-mi:bms1_yeast(display_long)|uniprotkb:YPL217C(locus name)|uniprotkb:BMS1(gene name)|psi-mi:BMS1(display_short)	psi-mi:rcl1_yeast(display_long)|uniprotkb:RCL1(gene name)|psi-mi:RCL1(display_short)|uniprotkb:RTC1(gene name synonym)|uniprotkb:YOL010W(locus name)	psi-mi:"MI:0018"(two hybrid)	Wegierski et al. (2001)	pubmed:11565748|imex:IM-19201	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2290722|imex:IM-19201-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015107.1|sgd:S000006138|dip:DIP-6562N|mint:Q08965|ensemblfungi:YPL217C(gene)|ensemblfungi:YPL217C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000479"("endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0030686"(90S preribosome)|go:"GO:0034511"(U3 snoRNA binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR007034(Protein of unknown function DUF663)|interpro:IPR012948(AARP2CN)|interpro:IPR027417|interpro:IPR030387|interpro:IPR037875|interpro:IPR039761|rcsb pdb:4CLQ|rcsb pdb:5JPQ|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226	refseq:NP_014633.1|sgd:S000005370|go:"GO:0000479"("endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030686"(90S preribosome)|interpro:IPR000228(RNA 3'-terminal phosphate cyclase)|interpro:IPR013791(RNA 3'-terminal phosphate cyclase, subset, insert region)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR016443(RNA 3'-terminal phosphate cyclase-like, eukaryotic)|interpro:IPR020719|interpro:IPR023797|interpro:IPR036553|interpro:IPR037136|rcsb pdb:4CLQ|rcsb pdb:5JPQ|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|ensemblfungi:YOL010W(gene)|ensemblfungi:YOL010W_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|dip:DIP-4539N|mint:Q08096	-	crc64:9A337F1EE0B0F21D	crc64:C5DDA7F9B0C1E296	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/03/13	2014/10/16	rogid:wG8wlE3l3G1E7VJiO/epPEDxTOE559292	rogid:wYe82ZA+YhfdftbYKX8+GBxQojo559292	intact-crc:A258A3A2C35352C5|rigid:ZXyAyPFAEtKNWbMhy2RIgoy7WKM	false	sufficient binding region:535-661	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08096	uniprotkb:Q08965	intact:EBI-14892|uniprotkb:D6W257|ensemblfungi:YOL010W	intact:EBI-3683|uniprotkb:D6W3F3|ensemblfungi:YPL217C	psi-mi:rcl1_yeast(display_long)|uniprotkb:RCL1(gene name)|psi-mi:RCL1(display_short)|uniprotkb:RTC1(gene name synonym)|uniprotkb:YOL010W(locus name)	psi-mi:bms1_yeast(display_long)|uniprotkb:YPL217C(locus name)|uniprotkb:BMS1(gene name)|psi-mi:BMS1(display_short)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Wegierski et al. (2001)	pubmed:11565748|imex:IM-19201	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2291734|imex:IM-19201-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014633.1|sgd:S000005370|go:"GO:0000479"("endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030686"(90S preribosome)|interpro:IPR000228(RNA 3'-terminal phosphate cyclase)|interpro:IPR013791(RNA 3'-terminal phosphate cyclase, subset, insert region)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR016443(RNA 3'-terminal phosphate cyclase-like, eukaryotic)|interpro:IPR020719|interpro:IPR023797|interpro:IPR036553|interpro:IPR037136|rcsb pdb:4CLQ|rcsb pdb:5JPQ|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|ensemblfungi:YOL010W(gene)|ensemblfungi:YOL010W_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|dip:DIP-4539N|mint:Q08096	refseq:NP_015107.1|sgd:S000006138|dip:DIP-6562N|mint:Q08965|ensemblfungi:YPL217C(gene)|ensemblfungi:YPL217C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000479"("endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0030686"(90S preribosome)|go:"GO:0034511"(U3 snoRNA binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR007034(Protein of unknown function DUF663)|interpro:IPR012948(AARP2CN)|interpro:IPR027417|interpro:IPR030387|interpro:IPR037875|interpro:IPR039761|rcsb pdb:4CLQ|rcsb pdb:5JPQ|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226	-	crc64:C5DDA7F9B0C1E296	crc64:9A337F1EE0B0F21D	figure legend:Figure 6a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/03/13	2014/10/16	rogid:wYe82ZA+YhfdftbYKX8+GBxQojo559292	rogid:wG8wlE3l3G1E7VJiO/epPEDxTOE559292	intact-crc:1B4FB3A2CCDDD1B4|rigid:ZXyAyPFAEtKNWbMhy2RIgoy7WKM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)