#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P32527 uniprotkb:P38788 intact:EBI-29684|uniprotkb:D6VV62|ensemblfungi:YGR285C intact:EBI-24570|uniprotkb:D3DL13|uniprotkb:Q6B1F3|uniprotkb:Q6TQT7|uniprotkb:Q6TQT8|ensemblfungi:YHR064C psi-mi:zuo1_yeast(display_long)|uniprotkb:Ribosome-associated complex subunit ZUO1(gene name synonym)|uniprotkb:DnaJ-related protein ZUO1(gene name synonym)|uniprotkb:Heat shock protein 40 homolog ZUO1(gene name synonym)|uniprotkb:ZUO1(gene name)|psi-mi:ZUO1(display_short)|uniprotkb:YGR285C(locus name) psi-mi:ssz1_yeast(display_long)|uniprotkb:YHR064C(locus name)|uniprotkb:SSZ1(gene name)|psi-mi:SSZ1(display_short)|uniprotkb:PDR13(gene name synonym)|uniprotkb:Heat shock protein 70 homolog SSZ1(gene name synonym)|uniprotkb:DnaK-related protein SSZ1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 13(gene name synonym) psi-mi:"MI:0091"(chromatography technology) Gautschi et al. (2001) pubmed:11274393|imex:IM-20394 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2478970|imex:IM-20394-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011801.1|sgd:S000003517|dip:DIP-4720N|mint:P32527|ensemblfungi:YGR285C(gene)|ensemblfungi:YGR285C_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0006452"(translational frameshifting)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0043022"(ribosome binding)|go:"GO:0051083"('de novo' cotranslational protein folding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071409"(cellular response to cycloheximide)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR032003|interpro:IPR036869|interpro:IPR042569|interpro:IPR044634|rcsb pdb:2LWX|rcsb pdb:5DJE refseq:NP_011931.2|sgd:S000001106|dip:DIP-6305N|mint:P38788|ensemblfungi:YHR064C(gene)|ensemblfungi:YHR064C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0006452"(translational frameshifting)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051083"('de novo' cotranslational protein folding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR029047|interpro:IPR043129 - crc64:0AA76BC11D3C7DAB crc64:07B1A409B213E0B4 figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/11/13 2014/10/16 rogid:o6WW+l9KMfneIM40Is/6zvBXxXo559292 rogid:cRp0pVkPyPmBw5LR59+WVZlFFV4559292 intact-crc:89173094758F0332|rigid:LZMg/JYWKddCVrY40PDgJ1SR/s8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32527 uniprotkb:P38788 intact:EBI-29684|uniprotkb:D6VV62|ensemblfungi:YGR285C intact:EBI-24570|uniprotkb:D3DL13|uniprotkb:Q6B1F3|uniprotkb:Q6TQT7|uniprotkb:Q6TQT8|ensemblfungi:YHR064C psi-mi:zuo1_yeast(display_long)|uniprotkb:Ribosome-associated complex subunit ZUO1(gene name synonym)|uniprotkb:DnaJ-related protein ZUO1(gene name synonym)|uniprotkb:Heat shock protein 40 homolog ZUO1(gene name synonym)|uniprotkb:ZUO1(gene name)|psi-mi:ZUO1(display_short)|uniprotkb:YGR285C(locus name) psi-mi:ssz1_yeast(display_long)|uniprotkb:YHR064C(locus name)|uniprotkb:SSZ1(gene name)|psi-mi:SSZ1(display_short)|uniprotkb:PDR13(gene name synonym)|uniprotkb:Heat shock protein 70 homolog SSZ1(gene name synonym)|uniprotkb:DnaK-related protein SSZ1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 13(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gautschi et al. (2001) pubmed:11274393|imex:IM-20394 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2478983|imex:IM-20394-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011801.1|sgd:S000003517|dip:DIP-4720N|mint:P32527|ensemblfungi:YGR285C(gene)|ensemblfungi:YGR285C_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0006452"(translational frameshifting)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0043022"(ribosome binding)|go:"GO:0051083"('de novo' cotranslational protein folding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071409"(cellular response to cycloheximide)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR032003|interpro:IPR036869|interpro:IPR042569|interpro:IPR044634|rcsb pdb:2LWX|rcsb pdb:5DJE refseq:NP_011931.2|sgd:S000001106|dip:DIP-6305N|mint:P38788|ensemblfungi:YHR064C(gene)|ensemblfungi:YHR064C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0006452"(translational frameshifting)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051083"('de novo' cotranslational protein folding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR029047|interpro:IPR043129 - crc64:0AA76BC11D3C7DAB crc64:07B1A409B213E0B4 figure legend:Fig. 3A|comment:Coimmunoprecipitation of the two subunits was unaffected by the addition of 2 mM ATP or ADP.|caution:A small amount of Ssa1/2p but was discounted by the author as non-specific binding.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/11/13 2014/10/16 rogid:o6WW+l9KMfneIM40Is/6zvBXxXo559292 rogid:cRp0pVkPyPmBw5LR59+WVZlFFV4559292 intact-crc:881B6DCEF7A71C1F|rigid:LZMg/JYWKddCVrY40PDgJ1SR/s8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P38788 uniprotkb:P32527 intact:EBI-24570|uniprotkb:D3DL13|uniprotkb:Q6B1F3|uniprotkb:Q6TQT7|uniprotkb:Q6TQT8|ensemblfungi:YHR064C intact:EBI-29684|uniprotkb:D6VV62|ensemblfungi:YGR285C psi-mi:ssz1_yeast(display_long)|uniprotkb:YHR064C(locus name)|uniprotkb:SSZ1(gene name)|psi-mi:SSZ1(display_short)|uniprotkb:PDR13(gene name synonym)|uniprotkb:Heat shock protein 70 homolog SSZ1(gene name synonym)|uniprotkb:DnaK-related protein SSZ1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 13(gene name synonym) psi-mi:zuo1_yeast(display_long)|uniprotkb:Ribosome-associated complex subunit ZUO1(gene name synonym)|uniprotkb:DnaJ-related protein ZUO1(gene name synonym)|uniprotkb:Heat shock protein 40 homolog ZUO1(gene name synonym)|uniprotkb:ZUO1(gene name)|psi-mi:ZUO1(display_short)|uniprotkb:YGR285C(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gautschi et al. (2001) pubmed:11274393|imex:IM-20394 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2478990|imex:IM-20394-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011931.2|sgd:S000001106|dip:DIP-6305N|mint:P38788|ensemblfungi:YHR064C(gene)|ensemblfungi:YHR064C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0006452"(translational frameshifting)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051083"('de novo' cotranslational protein folding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR029047|interpro:IPR043129 refseq:NP_011801.1|sgd:S000003517|dip:DIP-4720N|mint:P32527|ensemblfungi:YGR285C(gene)|ensemblfungi:YGR285C_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0006452"(translational frameshifting)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0043022"(ribosome binding)|go:"GO:0051083"('de novo' cotranslational protein folding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071409"(cellular response to cycloheximide)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR032003|interpro:IPR036869|interpro:IPR042569|interpro:IPR044634|rcsb pdb:2LWX|rcsb pdb:5DJE - crc64:07B1A409B213E0B4 crc64:0AA76BC11D3C7DAB figure legend:Fig. 3A|comment:Coimmunoprecipitation of the two subunits was unaffected by the addition of 2 mM ATP or ADP.|caution:A small amount of Ssa1/2p but was discounted by the author as non-specific binding.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/11/13 2014/10/16 rogid:cRp0pVkPyPmBw5LR59+WVZlFFV4559292 rogid:o6WW+l9KMfneIM40Is/6zvBXxXo559292 intact-crc:9B5586AE893ED08E|rigid:LZMg/JYWKddCVrY40PDgJ1SR/s8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32527 uniprotkb:P38788 intact:EBI-29684|uniprotkb:D6VV62|ensemblfungi:YGR285C intact:EBI-24570|uniprotkb:D3DL13|uniprotkb:Q6B1F3|uniprotkb:Q6TQT7|uniprotkb:Q6TQT8|ensemblfungi:YHR064C psi-mi:zuo1_yeast(display_long)|uniprotkb:Ribosome-associated complex subunit ZUO1(gene name synonym)|uniprotkb:DnaJ-related protein ZUO1(gene name synonym)|uniprotkb:Heat shock protein 40 homolog ZUO1(gene name synonym)|uniprotkb:ZUO1(gene name)|psi-mi:ZUO1(display_short)|uniprotkb:YGR285C(locus name) psi-mi:ssz1_yeast(display_long)|uniprotkb:YHR064C(locus name)|uniprotkb:SSZ1(gene name)|psi-mi:SSZ1(display_short)|uniprotkb:PDR13(gene name synonym)|uniprotkb:Heat shock protein 70 homolog SSZ1(gene name synonym)|uniprotkb:DnaK-related protein SSZ1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 13(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Gautschi et al. (2001) pubmed:11274393|imex:IM-20394 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479003|imex:IM-20394-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011801.1|sgd:S000003517|dip:DIP-4720N|mint:P32527|ensemblfungi:YGR285C(gene)|ensemblfungi:YGR285C_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0006452"(translational frameshifting)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0043022"(ribosome binding)|go:"GO:0051083"('de novo' cotranslational protein folding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071409"(cellular response to cycloheximide)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR032003|interpro:IPR036869|interpro:IPR042569|interpro:IPR044634|rcsb pdb:2LWX|rcsb pdb:5DJE refseq:NP_011931.2|sgd:S000001106|dip:DIP-6305N|mint:P38788|ensemblfungi:YHR064C(gene)|ensemblfungi:YHR064C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0006452"(translational frameshifting)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051083"('de novo' cotranslational protein folding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR029047|interpro:IPR043129 - crc64:0AA76BC11D3C7DAB crc64:07B1A409B213E0B4 figure legend:Fig. 3B|complex-properties:Complex m.w.=126,000 Da|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/11/13 2014/10/16 rogid:o6WW+l9KMfneIM40Is/6zvBXxXo559292 rogid:cRp0pVkPyPmBw5LR59+WVZlFFV4559292 intact-crc:1DB9637ABA158A1A|rigid:LZMg/JYWKddCVrY40PDgJ1SR/s8 false - - 1 1 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)