#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O35685 uniprotkb:P43034 intact:EBI-911192|ensembl:ENSMUSP00000030665|uniprotkb:Q3UJS7 intact:EBI-720620|uniprotkb:Q8WZ88|uniprotkb:Q8WZ89|uniprotkb:B2R7Q7|ensembl:ENSP00000380378|ensembl:ENSP00000501969|ensembl:ENSP00000502031|ensembl:ENSP00000502577|ensembl:ENSP00000502735|ensembl:ENSP00000502843 psi-mi:nudc_mouse(display_long)|uniprotkb:Nuclear distribution protein C homolog(gene name synonym)|uniprotkb:Silica-induced gene 92 protein(gene name synonym)|uniprotkb:Nudc(gene name)|psi-mi:Nudc(display_short) psi-mi:lis1_human(display_long)|uniprotkb:PAF acetylhydrolase 45 kDa subunit(gene name synonym)|uniprotkb:PAF-AH alpha(gene name synonym)|uniprotkb:Lissencephaly-1 protein(gene name synonym)|uniprotkb:PAFAH1B1(gene name)|psi-mi:PAFAH1B1(display_short)|uniprotkb:LIS1(gene name synonym)|uniprotkb:MDCR(gene name synonym)|uniprotkb:PAFAHA(gene name synonym)|uniprotkb:MDS(gene name synonym) psi-mi:"MI:0018"(two hybrid) Feng et al. (2000) pubmed:11163258|imex:IM-19200 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2272786|imex:IM-19200-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028851(gene)|ensembl:ENSMUST00000030665(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007097"(nuclear migration)|go:"GO:0030496"(midbody)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR025934|interpro:IPR032572|interpro:IPR037898|mint:O35685|rcsb pdb:1WFI|rcsb pdb:2CR0|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-9648025|reactome:R-MMU-9696270|refseq:NP_035078.1 refseq:NP_000421.1|ensembl:ENSG00000007168(gene)|ensembl:ENST00000397195(transcript)|ensembl:ENST00000675202(transcript)|ensembl:ENST00000675331(transcript)|ensembl:ENST00000675390(transcript)|ensembl:ENST00000676098(transcript)|ensembl:ENST00000676188(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000235"(astral microtubule)|go:"GO:0000776"(kinetochore)|refseq:XP_016880188.1|refseq:XP_016880189.1|refseq:XP_016880190.1|dip:DIP-35691N|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001675"(acrosome assembly)|go:"GO:0001764"(neuron migration)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007097"(nuclear migration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007281"(germ cell development)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007611"(learning or memory)|go:"GO:0008017"(microtubule binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008201"(heparin binding)|go:"GO:0008247"(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:"GO:0009306"(protein secretion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0017145"(stem cell division)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0021540"(corpus callosum morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031514"(motile cilium)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0036035"(osteoclast development)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042249"(establishment of planar polarity of embryonic epithelium)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0045202"(synapse)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046469"(platelet activating factor metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0034452"(dynactin binding)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|mint:P43034|rcsb pdb:7MT1|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090102"(cochlea development)|go:"GO:0090176"(microtubule cytoskeleton organization involved in establishment of planar polarity)|go:"GO:0090724"(central region of growth cone)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR015943(WD40/YVTN repeat-like) - - - figure legend:Fig 1.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/03/13 2014/10/16 rogid:eTyJnGWQOOMlsBv/LGFjOPsg1Ro10090 rogid:CgijDhrO703mGYXvJ44BgQJfVgM9606 intact-crc:37684B9C9D6F5188|rigid:ZSE4CdReGGMUyJA6OMSRNPXE1Zs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9CZA6 uniprotkb:P43034 intact:EBI-309934|uniprotkb:Q3UBS6|uniprotkb:Q3UIC1|uniprotkb:Q9ERR0|ensembl:ENSMUSP00000023359 intact:EBI-720620|uniprotkb:Q8WZ88|uniprotkb:Q8WZ89|uniprotkb:B2R7Q7|ensembl:ENSP00000380378|ensembl:ENSP00000501969|ensembl:ENSP00000502031|ensembl:ENSP00000502577|ensembl:ENSP00000502735|ensembl:ENSP00000502843 psi-mi:nde1_mouse(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym) psi-mi:lis1_human(display_long)|uniprotkb:PAF acetylhydrolase 45 kDa subunit(gene name synonym)|uniprotkb:PAF-AH alpha(gene name synonym)|uniprotkb:Lissencephaly-1 protein(gene name synonym)|uniprotkb:PAFAH1B1(gene name)|psi-mi:PAFAH1B1(display_short)|uniprotkb:LIS1(gene name synonym)|uniprotkb:MDCR(gene name synonym)|uniprotkb:PAFAHA(gene name synonym)|uniprotkb:MDS(gene name synonym) psi-mi:"MI:0018"(two hybrid) Feng et al. (2000) pubmed:11163258|imex:IM-19200 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2272814|imex:IM-19200-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001107557.1|refseq:NP_075806.2|refseq:NP_001272432.1|refseq:NP_001272433.1|refseq:XP_011244302.1|ensembl:ENSMUSG00000022678(gene)|ensembl:ENSMUST00000023359(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9CZA6|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025|dip:DIP-54638N refseq:NP_000421.1|ensembl:ENSG00000007168(gene)|ensembl:ENST00000397195(transcript)|ensembl:ENST00000675202(transcript)|ensembl:ENST00000675331(transcript)|ensembl:ENST00000675390(transcript)|ensembl:ENST00000676098(transcript)|ensembl:ENST00000676188(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000235"(astral microtubule)|go:"GO:0000776"(kinetochore)|refseq:XP_016880188.1|refseq:XP_016880189.1|refseq:XP_016880190.1|dip:DIP-35691N|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001675"(acrosome assembly)|go:"GO:0001764"(neuron migration)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007097"(nuclear migration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007281"(germ cell development)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007611"(learning or memory)|go:"GO:0008017"(microtubule binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008201"(heparin binding)|go:"GO:0008247"(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:"GO:0009306"(protein secretion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0017145"(stem cell division)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0021540"(corpus callosum morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031514"(motile cilium)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0036035"(osteoclast development)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042249"(establishment of planar polarity of embryonic epithelium)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0045202"(synapse)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046469"(platelet activating factor metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0034452"(dynactin binding)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|mint:P43034|rcsb pdb:7MT1|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090102"(cochlea development)|go:"GO:0090176"(microtubule cytoskeleton organization involved in establishment of planar polarity)|go:"GO:0090724"(central region of growth cone)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR015943(WD40/YVTN repeat-like) - - - figure legend:Fig 1.|comment:"Lis1 interacts with NudE (nde1)."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/03/13 2014/10/16 rogid:711HNgfdXkDQEAEhRwa4DjKah5s10090 rogid:CgijDhrO703mGYXvJ44BgQJfVgM9606 intact-crc:E75FD25A2E4F7697|rigid:7b/s4gBnXTadoRnK4MD4SEw42yA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P48725 uniprotkb:Q9CZA6 intact:EBI-2290976|uniprotkb:A0JBT0|uniprotkb:A0JBT1 intact:EBI-309934|uniprotkb:Q3UBS6|uniprotkb:Q3UIC1|uniprotkb:Q9ERR0|ensembl:ENSMUSP00000023359 psi-mi:pcnt_mouse(display_long)|uniprotkb:Pcnt(gene name)|psi-mi:Pcnt(display_short)|uniprotkb:Pcnt2(gene name synonym) psi-mi:nde1_mouse(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym) psi-mi:"MI:0018"(two hybrid) Feng et al. (2000) pubmed:11163258|imex:IM-19200 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2290971|imex:IM-19200-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269921.1|refseq:NP_032813.3|interpro:IPR019528|interpro:IPR028745|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-8854518|reactome:R-MMU-9646399|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0001822"(kidney development)|go:"GO:0001944"(vasculature development)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007165"(signal transduction)|go:"GO:0021696"(cerebellar cortex morphogenesis)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0031514"(motile cilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:1990403"(embryonic brain development) refseq:NP_001107557.1|refseq:NP_075806.2|refseq:NP_001272432.1|refseq:NP_001272433.1|refseq:XP_011244302.1|ensembl:ENSMUSG00000022678(gene)|ensembl:ENSMUST00000023359(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9CZA6|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025|dip:DIP-54638N - - - figure legend:Fig. 5A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/03/13 2014/10/16 rogid:1uo9aCCB8laEBPn83Udu0EY2wco10090 rogid:711HNgfdXkDQEAEhRwa4DjKah5s10090 intact-crc:1E081752E34B71FD|rigid:qZ+IO6lRL1NO1o0nWzNs6idc2Fs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q155P7 uniprotkb:Q9CZA6 intact:EBI-2211248 intact:EBI-309934|uniprotkb:Q3UBS6|uniprotkb:Q3UIC1|uniprotkb:Q9ERR0|ensembl:ENSMUSP00000023359 psi-mi:q155p7_mouse(display_long)|uniprotkb:Cenpf(gene name)|psi-mi:Cenpf(display_short)|uniprotkb:Lek1(gene name synonym) psi-mi:nde1_mouse(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym) psi-mi:"MI:0018"(two hybrid) Feng et al. (2000) pubmed:11163258|imex:IM-19200 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2290988|imex:IM-19200-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019513|interpro:IPR018463|interpro:IPR018302|interpro:IPR043513|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001822"(kidney development)|go:"GO:0002724"(regulation of T cell cytokine production)|go:"GO:0002730"(regulation of dendritic cell cytokine production)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030496"(midbody)|go:"GO:0030885"(regulation of myeloid dendritic cell activation)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045120"(pronucleus)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048866"(stem cell fate specification)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0055037"(recycling endosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097539"(ciliary transition fiber) refseq:NP_001107557.1|refseq:NP_075806.2|refseq:NP_001272432.1|refseq:NP_001272433.1|refseq:XP_011244302.1|ensembl:ENSMUSG00000022678(gene)|ensembl:ENSMUST00000023359(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9CZA6|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025|dip:DIP-54638N - - - figure legend:Fig. 6A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/03/13 2014/10/16 rogid:b3rPf5eE6WotbUeJcEwHdYF9Gwg10090 rogid:711HNgfdXkDQEAEhRwa4DjKah5s10090 intact-crc:60C06E8EB4005A5A|rigid:TdOH42/RJVjdyXvrtRz2IoWUuQg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7TSH4 uniprotkb:Q9CZA6 intact:EBI-646843|uniprotkb:Q6A072|ensembl:ENSMUSP00000038881|ensembl:ENSMUSP00000102167 intact:EBI-309934|uniprotkb:Q3UBS6|uniprotkb:Q3UIC1|uniprotkb:Q9ERR0|ensembl:ENSMUSP00000023359 psi-mi:cp110_mouse(display_long)|uniprotkb:Cep110(gene name synonym)|uniprotkb:Ccp110(gene name)|psi-mi:Ccp110(display_short)|uniprotkb:Kiaa0419(gene name synonym)|uniprotkb:Cp110(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:nde1_mouse(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym) psi-mi:"MI:0018"(two hybrid) Feng et al. (2000) pubmed:11163258|imex:IM-19200 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2290993|imex:IM-19200-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_892040.1|ensembl:ENSMUSG00000033904(gene)|ensembl:ENSMUST00000038650(transcript)|ensembl:ENSMUST00000106557(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5689880|reactome:R-MMU-8854518|reactome:R-MMU-9013424 refseq:NP_001107557.1|refseq:NP_075806.2|refseq:NP_001272432.1|refseq:NP_001272433.1|refseq:XP_011244302.1|ensembl:ENSMUSG00000022678(gene)|ensembl:ENSMUST00000023359(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9CZA6|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025|dip:DIP-54638N - - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/03/13 2014/10/16 rogid:Ma+OC215nDGgK9D4XMR9h7X4EV410090 rogid:711HNgfdXkDQEAEhRwa4DjKah5s10090 intact-crc:07444F0B00C0AD09|rigid:crjjR9grgLcO3IwX4k16kjbdbuk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P11983 uniprotkb:Q9CZA6 intact:EBI-772338|uniprotkb:Q3TJ96|uniprotkb:Q3TKU1|uniprotkb:Q3U5T8|uniprotkb:Q3U7I8|uniprotkb:Q3UAA8|uniprotkb:Q3UB80|uniprotkb:Q3UE48|intact:EBI-2291308|uniprotkb:P11984|ensembl:ENSMUSP00000116108 intact:EBI-309934|uniprotkb:Q3UBS6|uniprotkb:Q3UIC1|uniprotkb:Q9ERR0|ensembl:ENSMUSP00000023359 psi-mi:tcpa_mouse(display_long)|uniprotkb:CCT-alpha(gene name synonym)|uniprotkb:Tailless complex polypeptide 1B(gene name synonym)|uniprotkb:Tcp1(gene name)|psi-mi:Tcp1(display_short)|uniprotkb:Ccta(gene name synonym)|uniprotkb:Cct1(gene name synonym)|uniprotkb:Tailless complex polypeptide 1A(gene name synonym) psi-mi:nde1_mouse(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym) psi-mi:"MI:0018"(two hybrid) Feng et al. (2000) pubmed:11163258|imex:IM-19200 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2291301|imex:IM-19200-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001277641.1|refseq:NP_038714.2|dip:DIP-32342N|ensembl:ENSMUSG00000068039(gene)|ensembl:ENSMUST00000151287(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P11983|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6814122 refseq:NP_001107557.1|refseq:NP_075806.2|refseq:NP_001272432.1|refseq:NP_001272433.1|refseq:XP_011244302.1|ensembl:ENSMUSG00000022678(gene)|ensembl:ENSMUST00000023359(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9CZA6|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025|dip:DIP-54638N - - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/03/13 2014/10/16 rogid:mSINCow3H5FzUCTXpqwkI18OI9o10090 rogid:711HNgfdXkDQEAEhRwa4DjKah5s10090 intact-crc:1648CB2A733C236D|rigid:vcWhoN2F1hILe7DlLbwLrH+FJhk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q60898 uniprotkb:Q9CZA6 intact:EBI-2291369|uniprotkb:Q8C9Q8|uniprotkb:Q8CAT0|uniprotkb:Q8CBE9|uniprotkb:Q8QZX8|ensembl:ENSMUSP00000098138|ensembl:ENSMUSP00000127901|ensembl:ENSMUSP00000130222 intact:EBI-309934|uniprotkb:Q3UBS6|uniprotkb:Q3UIC1|uniprotkb:Q9ERR0|ensembl:ENSMUSP00000023359 psi-mi:slap1_mouse(display_long)|uniprotkb:Sla(gene name)|psi-mi:Sla(display_short)|uniprotkb:Slap(gene name synonym)|uniprotkb:Slap1(gene name synonym)|uniprotkb:Src-like-adapter protein 1(gene name synonym) psi-mi:nde1_mouse(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym) psi-mi:"MI:0018"(two hybrid) Feng et al. (2000) pubmed:11163258|imex:IM-19200 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2291365|imex:IM-19200-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011243832.1|refseq:NP_001025012.1|refseq:NP_033218.1|ensembl:ENSMUSG00000022372(gene)|ensembl:ENSMUST00000100572(transcript)|ensembl:ENSMUST00000164163(transcript)|ensembl:ENSMUST00000168589(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005768"(endosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0045087"(innate immune response)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035052|interpro:IPR035055|interpro:IPR035596|interpro:IPR036028|interpro:IPR036860|reactome:R-MMU-9706369|dip:DIP-292N refseq:NP_001107557.1|refseq:NP_075806.2|refseq:NP_001272432.1|refseq:NP_001272433.1|refseq:XP_011244302.1|ensembl:ENSMUSG00000022678(gene)|ensembl:ENSMUST00000023359(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9CZA6|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025|dip:DIP-54638N - - - figure legend:Fig 6A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/03/13 2014/10/16 rogid:0GqIVcXi/xaWKRHb75FFkBIpnxQ10090 rogid:711HNgfdXkDQEAEhRwa4DjKah5s10090 intact-crc:801912DAE3335204|rigid:VT5FS3/M17yvtvfntSxxocjLaHo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9CZA6 uniprotkb:P63168 intact:EBI-309934|uniprotkb:Q3UBS6|uniprotkb:Q3UIC1|uniprotkb:Q9ERR0|ensembl:ENSMUSP00000023359 intact:EBI-349121|uniprotkb:Q15701|ensembl:ENSMUSP00000107720|ensembl:ENSMUSP00000009157|uniprotkb:Q3UGE7 psi-mi:nde1_mouse(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym) psi-mi:dyl1_mouse(display_long)|uniprotkb:Dynll1(gene name)|psi-mi:Dynll1(display_short)|uniprotkb:Dlc1(gene name synonym)|uniprotkb:Dnclc1(gene name synonym)|uniprotkb:Dncl1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym) psi-mi:"MI:0018"(two hybrid) Feng et al. (2000) pubmed:11163258|imex:IM-19200 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2291393|imex:IM-19200-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001107557.1|refseq:NP_075806.2|refseq:NP_001272432.1|refseq:NP_001272433.1|refseq:XP_011244302.1|ensembl:ENSMUSG00000022678(gene)|ensembl:ENSMUST00000023359(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9CZA6|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025|dip:DIP-54638N refseq:NP_062656.3|ensembl:ENSMUST00000009157(transcript)|ensembl:ENSMUST00000112090(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|ensembl:ENSMUSG00000009013(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0030141"(secretory granule)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035721"(intraciliary retrograde transport)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63168|reactome:R-MMU-111446|reactome:R-MMU-141444|reactome:R-MMU-1632852|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5663220|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9646399|reactome:R-MMU-9648025 - - - figure legend:Fig. 6A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/03/13 2014/10/16 rogid:711HNgfdXkDQEAEhRwa4DjKah5s10090 rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv8010090 intact-crc:FC4D043AD385ABCB|rigid:asmdvLCFSUDg8v3rO9oxpkyS31E false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9CZA6 uniprotkb:P43034 intact:EBI-309934|uniprotkb:Q3UBS6|uniprotkb:Q3UIC1|uniprotkb:Q9ERR0|ensembl:ENSMUSP00000023359 intact:EBI-720620|uniprotkb:Q8WZ88|uniprotkb:Q8WZ89|uniprotkb:B2R7Q7|ensembl:ENSP00000380378|ensembl:ENSP00000501969|ensembl:ENSP00000502031|ensembl:ENSP00000502577|ensembl:ENSP00000502735|ensembl:ENSP00000502843 psi-mi:nde1_mouse(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym) psi-mi:lis1_human(display_long)|uniprotkb:PAF acetylhydrolase 45 kDa subunit(gene name synonym)|uniprotkb:PAF-AH alpha(gene name synonym)|uniprotkb:Lissencephaly-1 protein(gene name synonym)|uniprotkb:PAFAH1B1(gene name)|psi-mi:PAFAH1B1(display_short)|uniprotkb:LIS1(gene name synonym)|uniprotkb:MDCR(gene name synonym)|uniprotkb:PAFAHA(gene name synonym)|uniprotkb:MDS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Feng et al. (2000) pubmed:11163258|imex:IM-19200 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2272826|imex:IM-19200-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001107557.1|refseq:NP_075806.2|refseq:NP_001272432.1|refseq:NP_001272433.1|refseq:XP_011244302.1|ensembl:ENSMUSG00000022678(gene)|ensembl:ENSMUST00000023359(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9CZA6|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025|dip:DIP-54638N refseq:NP_000421.1|ensembl:ENSG00000007168(gene)|ensembl:ENST00000397195(transcript)|ensembl:ENST00000675202(transcript)|ensembl:ENST00000675331(transcript)|ensembl:ENST00000675390(transcript)|ensembl:ENST00000676098(transcript)|ensembl:ENST00000676188(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000235"(astral microtubule)|go:"GO:0000776"(kinetochore)|refseq:XP_016880188.1|refseq:XP_016880189.1|refseq:XP_016880190.1|dip:DIP-35691N|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001675"(acrosome assembly)|go:"GO:0001764"(neuron migration)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007097"(nuclear migration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007281"(germ cell development)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007611"(learning or memory)|go:"GO:0008017"(microtubule binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008201"(heparin binding)|go:"GO:0008247"(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:"GO:0009306"(protein secretion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0017145"(stem cell division)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0021540"(corpus callosum morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031514"(motile cilium)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0036035"(osteoclast development)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042249"(establishment of planar polarity of embryonic epithelium)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0045202"(synapse)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046469"(platelet activating factor metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0034452"(dynactin binding)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|mint:P43034|rcsb pdb:7MT1|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090102"(cochlea development)|go:"GO:0090176"(microtubule cytoskeleton organization involved in establishment of planar polarity)|go:"GO:0090724"(central region of growth cone)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR015943(WD40/YVTN repeat-like) - - - figure legend:Fig 2A.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2009/03/13 2014/10/16 rogid:711HNgfdXkDQEAEhRwa4DjKah5s10090 rogid:CgijDhrO703mGYXvJ44BgQJfVgM9606 intact-crc:EB0D0735550881A5|rigid:7b/s4gBnXTadoRnK4MD4SEw42yA false myc tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P43034 uniprotkb:Q9CZA6 intact:EBI-720620|uniprotkb:Q8WZ88|uniprotkb:Q8WZ89|uniprotkb:B2R7Q7|ensembl:ENSP00000380378|ensembl:ENSP00000501969|ensembl:ENSP00000502031|ensembl:ENSP00000502577|ensembl:ENSP00000502735|ensembl:ENSP00000502843 intact:EBI-309934|uniprotkb:Q3UBS6|uniprotkb:Q3UIC1|uniprotkb:Q9ERR0|ensembl:ENSMUSP00000023359 psi-mi:lis1_human(display_long)|uniprotkb:PAF acetylhydrolase 45 kDa subunit(gene name synonym)|uniprotkb:PAF-AH alpha(gene name synonym)|uniprotkb:Lissencephaly-1 protein(gene name synonym)|uniprotkb:PAFAH1B1(gene name)|psi-mi:PAFAH1B1(display_short)|uniprotkb:LIS1(gene name synonym)|uniprotkb:MDCR(gene name synonym)|uniprotkb:PAFAHA(gene name synonym)|uniprotkb:MDS(gene name synonym) psi-mi:nde1_mouse(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym) psi-mi:"MI:0018"(two hybrid) Feng et al. (2000) pubmed:11163258|imex:IM-19200 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2275892|imex:IM-19200-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000421.1|ensembl:ENSG00000007168(gene)|ensembl:ENST00000397195(transcript)|ensembl:ENST00000675202(transcript)|ensembl:ENST00000675331(transcript)|ensembl:ENST00000675390(transcript)|ensembl:ENST00000676098(transcript)|ensembl:ENST00000676188(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000235"(astral microtubule)|go:"GO:0000776"(kinetochore)|refseq:XP_016880188.1|refseq:XP_016880189.1|refseq:XP_016880190.1|dip:DIP-35691N|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001675"(acrosome assembly)|go:"GO:0001764"(neuron migration)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007097"(nuclear migration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007281"(germ cell development)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007611"(learning or memory)|go:"GO:0008017"(microtubule binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008201"(heparin binding)|go:"GO:0008247"(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:"GO:0009306"(protein secretion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0017145"(stem cell division)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0021540"(corpus callosum morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031514"(motile cilium)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0036035"(osteoclast development)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042249"(establishment of planar polarity of embryonic epithelium)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0045202"(synapse)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046469"(platelet activating factor metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0034452"(dynactin binding)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|mint:P43034|rcsb pdb:7MT1|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090102"(cochlea development)|go:"GO:0090176"(microtubule cytoskeleton organization involved in establishment of planar polarity)|go:"GO:0090724"(central region of growth cone)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR015943(WD40/YVTN repeat-like) refseq:NP_001107557.1|refseq:NP_075806.2|refseq:NP_001272432.1|refseq:NP_001272433.1|refseq:XP_011244302.1|ensembl:ENSMUSG00000022678(gene)|ensembl:ENSMUST00000023359(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9CZA6|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025|dip:DIP-54638N - - - figure legend:Fig 2C.|comment:"The sites at amino acid positions 149 and 169 in the lis1 protein play an important role in binding to nude (nde1)."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/03/13 2014/10/16 rogid:CgijDhrO703mGYXvJ44BgQJfVgM9606 rogid:711HNgfdXkDQEAEhRwa4DjKah5s10090 intact-crc:16DEEB5224CA33E9|rigid:7b/s4gBnXTadoRnK4MD4SEw42yA false mutation decreasing interaction:149-149|mutation decreasing interaction:169-169 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P63168 uniprotkb:Q9CZA6 intact:EBI-349121|uniprotkb:Q15701|ensembl:ENSMUSP00000107720|ensembl:ENSMUSP00000009157|uniprotkb:Q3UGE7 intact:EBI-309934|uniprotkb:Q3UBS6|uniprotkb:Q3UIC1|uniprotkb:Q9ERR0|ensembl:ENSMUSP00000023359 psi-mi:dyl1_mouse(display_long)|uniprotkb:Dynll1(gene name)|psi-mi:Dynll1(display_short)|uniprotkb:Dlc1(gene name synonym)|uniprotkb:Dnclc1(gene name synonym)|uniprotkb:Dncl1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym) psi-mi:nde1_mouse(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym) psi-mi:"MI:0018"(two hybrid) Feng et al. (2000) pubmed:11163258|imex:IM-19200 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2320586|imex:IM-19200-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062656.3|ensembl:ENSMUST00000009157(transcript)|ensembl:ENSMUST00000112090(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|ensembl:ENSMUSG00000009013(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0030141"(secretory granule)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035721"(intraciliary retrograde transport)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63168|reactome:R-MMU-111446|reactome:R-MMU-141444|reactome:R-MMU-1632852|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5663220|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9646399|reactome:R-MMU-9648025 refseq:NP_001107557.1|refseq:NP_075806.2|refseq:NP_001272432.1|refseq:NP_001272433.1|refseq:XP_011244302.1|ensembl:ENSMUSG00000022678(gene)|ensembl:ENSMUST00000023359(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9CZA6|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025|dip:DIP-54638N - - - figure legend:Fig 6B.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/03/13 2014/10/16 rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv8010090 rogid:711HNgfdXkDQEAEhRwa4DjKah5s10090 intact-crc:0C84E1211BDF0FB0|rigid:asmdvLCFSUDg8v3rO9oxpkyS31E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CZA6 uniprotkb:P11983 intact:EBI-309934|uniprotkb:Q3UBS6|uniprotkb:Q3UIC1|uniprotkb:Q9ERR0|ensembl:ENSMUSP00000023359 intact:EBI-772338|uniprotkb:Q3TJ96|uniprotkb:Q3TKU1|uniprotkb:Q3U5T8|uniprotkb:Q3U7I8|uniprotkb:Q3UAA8|uniprotkb:Q3UB80|uniprotkb:Q3UE48|intact:EBI-2291308|uniprotkb:P11984|ensembl:ENSMUSP00000116108 psi-mi:nde1_mouse(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym) psi-mi:tcpa_mouse(display_long)|uniprotkb:CCT-alpha(gene name synonym)|uniprotkb:Tailless complex polypeptide 1B(gene name synonym)|uniprotkb:Tcp1(gene name)|psi-mi:Tcp1(display_short)|uniprotkb:Ccta(gene name synonym)|uniprotkb:Cct1(gene name synonym)|uniprotkb:Tailless complex polypeptide 1A(gene name synonym) psi-mi:"MI:0018"(two hybrid) Feng et al. (2000) pubmed:11163258|imex:IM-19200 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2320591|imex:IM-19200-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001107557.1|refseq:NP_075806.2|refseq:NP_001272432.1|refseq:NP_001272433.1|refseq:XP_011244302.1|ensembl:ENSMUSG00000022678(gene)|ensembl:ENSMUST00000023359(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9CZA6|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025|dip:DIP-54638N refseq:NP_001277641.1|refseq:NP_038714.2|dip:DIP-32342N|ensembl:ENSMUSG00000068039(gene)|ensembl:ENSMUST00000151287(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P11983|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6814122 - - - figure legend:Fig 6B.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/03/13 2014/10/16 rogid:711HNgfdXkDQEAEhRwa4DjKah5s10090 rogid:mSINCow3H5FzUCTXpqwkI18OI9o10090 intact-crc:758D3C0EE8A2BE58|rigid:vcWhoN2F1hILe7DlLbwLrH+FJhk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48725 uniprotkb:Q9CZA6 intact:EBI-2290976|uniprotkb:A0JBT0|uniprotkb:A0JBT1 intact:EBI-309934|uniprotkb:Q3UBS6|uniprotkb:Q3UIC1|uniprotkb:Q9ERR0|ensembl:ENSMUSP00000023359 psi-mi:pcnt_mouse(display_long)|uniprotkb:Pcnt(gene name)|psi-mi:Pcnt(display_short)|uniprotkb:Pcnt2(gene name synonym) psi-mi:nde1_mouse(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym) psi-mi:"MI:0018"(two hybrid) Feng et al. (2000) pubmed:11163258|imex:IM-19200 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2320597|imex:IM-19200-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269921.1|refseq:NP_032813.3|interpro:IPR019528|interpro:IPR028745|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-8854518|reactome:R-MMU-9646399|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0001822"(kidney development)|go:"GO:0001944"(vasculature development)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007165"(signal transduction)|go:"GO:0021696"(cerebellar cortex morphogenesis)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0031514"(motile cilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:1990403"(embryonic brain development) refseq:NP_001107557.1|refseq:NP_075806.2|refseq:NP_001272432.1|refseq:NP_001272433.1|refseq:XP_011244302.1|ensembl:ENSMUSG00000022678(gene)|ensembl:ENSMUST00000023359(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9CZA6|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025|dip:DIP-54638N - - - figure legend:Fig 6B.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/03/13 2014/10/16 rogid:1uo9aCCB8laEBPn83Udu0EY2wco10090 rogid:711HNgfdXkDQEAEhRwa4DjKah5s10090 intact-crc:7CA705BA3BB648C4|rigid:qZ+IO6lRL1NO1o0nWzNs6idc2Fs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CZA6 uniprotkb:Q60898 intact:EBI-309934|uniprotkb:Q3UBS6|uniprotkb:Q3UIC1|uniprotkb:Q9ERR0|ensembl:ENSMUSP00000023359 intact:EBI-2291369|uniprotkb:Q8C9Q8|uniprotkb:Q8CAT0|uniprotkb:Q8CBE9|uniprotkb:Q8QZX8|ensembl:ENSMUSP00000098138|ensembl:ENSMUSP00000127901|ensembl:ENSMUSP00000130222 psi-mi:nde1_mouse(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym) psi-mi:slap1_mouse(display_long)|uniprotkb:Sla(gene name)|psi-mi:Sla(display_short)|uniprotkb:Slap(gene name synonym)|uniprotkb:Slap1(gene name synonym)|uniprotkb:Src-like-adapter protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Feng et al. (2000) pubmed:11163258|imex:IM-19200 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2320602|imex:IM-19200-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001107557.1|refseq:NP_075806.2|refseq:NP_001272432.1|refseq:NP_001272433.1|refseq:XP_011244302.1|ensembl:ENSMUSG00000022678(gene)|ensembl:ENSMUST00000023359(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9CZA6|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025|dip:DIP-54638N refseq:XP_011243832.1|refseq:NP_001025012.1|refseq:NP_033218.1|ensembl:ENSMUSG00000022372(gene)|ensembl:ENSMUST00000100572(transcript)|ensembl:ENSMUST00000164163(transcript)|ensembl:ENSMUST00000168589(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005768"(endosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0045087"(innate immune response)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035052|interpro:IPR035055|interpro:IPR035596|interpro:IPR036028|interpro:IPR036860|reactome:R-MMU-9706369|dip:DIP-292N - - - figure legend:Fig 6B.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/03/13 2014/10/16 rogid:711HNgfdXkDQEAEhRwa4DjKah5s10090 rogid:0GqIVcXi/xaWKRHb75FFkBIpnxQ10090 intact-crc:817DFD8589C0AAD3|rigid:VT5FS3/M17yvtvfntSxxocjLaHo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7TSH4 uniprotkb:Q9CZA6 intact:EBI-646843|uniprotkb:Q6A072|ensembl:ENSMUSP00000038881|ensembl:ENSMUSP00000102167 intact:EBI-309934|uniprotkb:Q3UBS6|uniprotkb:Q3UIC1|uniprotkb:Q9ERR0|ensembl:ENSMUSP00000023359 psi-mi:cp110_mouse(display_long)|uniprotkb:Cep110(gene name synonym)|uniprotkb:Ccp110(gene name)|psi-mi:Ccp110(display_short)|uniprotkb:Kiaa0419(gene name synonym)|uniprotkb:Cp110(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:nde1_mouse(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym) psi-mi:"MI:0018"(two hybrid) Feng et al. (2000) pubmed:11163258|imex:IM-19200 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2320607|imex:IM-19200-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_892040.1|ensembl:ENSMUSG00000033904(gene)|ensembl:ENSMUST00000038650(transcript)|ensembl:ENSMUST00000106557(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5689880|reactome:R-MMU-8854518|reactome:R-MMU-9013424 refseq:NP_001107557.1|refseq:NP_075806.2|refseq:NP_001272432.1|refseq:NP_001272433.1|refseq:XP_011244302.1|ensembl:ENSMUSG00000022678(gene)|ensembl:ENSMUST00000023359(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9CZA6|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025|dip:DIP-54638N - - - figure legend:Fig 6B.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/03/13 2014/10/16 rogid:Ma+OC215nDGgK9D4XMR9h7X4EV410090 rogid:711HNgfdXkDQEAEhRwa4DjKah5s10090 intact-crc:CCA04EC288DF9CD4|rigid:crjjR9grgLcO3IwX4k16kjbdbuk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q155P7 uniprotkb:Q9CZA6 intact:EBI-2211248 intact:EBI-309934|uniprotkb:Q3UBS6|uniprotkb:Q3UIC1|uniprotkb:Q9ERR0|ensembl:ENSMUSP00000023359 psi-mi:q155p7_mouse(display_long)|uniprotkb:Cenpf(gene name)|psi-mi:Cenpf(display_short)|uniprotkb:Lek1(gene name synonym) psi-mi:nde1_mouse(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym) psi-mi:"MI:0018"(two hybrid) Feng et al. (2000) pubmed:11163258|imex:IM-19200 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2320612|imex:IM-19200-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019513|interpro:IPR018463|interpro:IPR018302|interpro:IPR043513|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001822"(kidney development)|go:"GO:0002724"(regulation of T cell cytokine production)|go:"GO:0002730"(regulation of dendritic cell cytokine production)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030496"(midbody)|go:"GO:0030885"(regulation of myeloid dendritic cell activation)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045120"(pronucleus)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048866"(stem cell fate specification)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0055037"(recycling endosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097539"(ciliary transition fiber) refseq:NP_001107557.1|refseq:NP_075806.2|refseq:NP_001272432.1|refseq:NP_001272433.1|refseq:XP_011244302.1|ensembl:ENSMUSG00000022678(gene)|ensembl:ENSMUST00000023359(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9CZA6|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025|dip:DIP-54638N - - - figure legend:Fig 6B.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/03/13 2014/10/16 rogid:b3rPf5eE6WotbUeJcEwHdYF9Gwg10090 rogid:711HNgfdXkDQEAEhRwa4DjKah5s10090 intact-crc:CC419C5E376143DC|rigid:TdOH42/RJVjdyXvrtRz2IoWUuQg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23258 uniprotkb:Q9CZA6 intact:EBI-302589|ensembl:ENSP00000251413|uniprotkb:Q9BW59|uniprotkb:Q53X79 intact:EBI-309934|uniprotkb:Q3UBS6|uniprotkb:Q3UIC1|uniprotkb:Q9ERR0|ensembl:ENSMUSP00000023359 psi-mi:tbg1_human(display_long)|uniprotkb:TUBG1(gene name)|psi-mi:TUBG1(display_short)|uniprotkb:TUBG(gene name synonym)|uniprotkb:Gamma-1-tubulin(gene name synonym)|uniprotkb:Gamma-tubulin complex component 1(gene name synonym) psi-mi:nde1_mouse(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Feng et al. (2000) pubmed:11163258|imex:IM-19200 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2291030|imex:IM-19200-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P23258|rcsb pdb:1Z5V|rcsb pdb:1Z5W|rcsb pdb:3CB2|rcsb pdb:6V5V|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|interpro:IPR017975|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000131462(gene)|ensembl:ENST00000251413(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005827"(polar microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0055037"(recycling endosome)|go:"GO:0097730"(non-motile cilium)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002454(Gamma tubulin)|go:"GO:0005814"(centriole)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|refseq:NP_001061.2|dip:DIP-29890N refseq:NP_001107557.1|refseq:NP_075806.2|refseq:NP_001272432.1|refseq:NP_001272433.1|refseq:XP_011244302.1|ensembl:ENSMUSG00000022678(gene)|ensembl:ENSMUST00000023359(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9CZA6|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025|dip:DIP-54638N - - - figure legend:Fig 6A.|comment:"NudE (nde1) interacts with gamma-tubulin but not with Lis1."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2009/03/13 2014/10/16 rogid:Y5WLH1ZKlS7FOa9ePmH3dpdE8Xk9606 rogid:711HNgfdXkDQEAEhRwa4DjKah5s10090 intact-crc:9012B30F29151E88|rigid:feoDkgYmVoiZRDvA6Cxp9Gpbmbo false - green fluorescent protein tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9CZA6 uniprotkb:P43034 intact:EBI-309934|uniprotkb:Q3UBS6|uniprotkb:Q3UIC1|uniprotkb:Q9ERR0|ensembl:ENSMUSP00000023359 intact:EBI-720620|uniprotkb:Q8WZ88|uniprotkb:Q8WZ89|uniprotkb:B2R7Q7|ensembl:ENSP00000380378|ensembl:ENSP00000501969|ensembl:ENSP00000502031|ensembl:ENSP00000502577|ensembl:ENSP00000502735|ensembl:ENSP00000502843 psi-mi:nde1_mouse(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym) psi-mi:lis1_human(display_long)|uniprotkb:PAF acetylhydrolase 45 kDa subunit(gene name synonym)|uniprotkb:PAF-AH alpha(gene name synonym)|uniprotkb:Lissencephaly-1 protein(gene name synonym)|uniprotkb:PAFAH1B1(gene name)|psi-mi:PAFAH1B1(display_short)|uniprotkb:LIS1(gene name synonym)|uniprotkb:MDCR(gene name synonym)|uniprotkb:PAFAHA(gene name synonym)|uniprotkb:MDS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Feng et al. (2000) pubmed:11163258|imex:IM-19200 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2290688|imex:IM-19200-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001107557.1|refseq:NP_075806.2|refseq:NP_001272432.1|refseq:NP_001272433.1|refseq:XP_011244302.1|ensembl:ENSMUSG00000022678(gene)|ensembl:ENSMUST00000023359(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9CZA6|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025|dip:DIP-54638N refseq:NP_000421.1|ensembl:ENSG00000007168(gene)|ensembl:ENST00000397195(transcript)|ensembl:ENST00000675202(transcript)|ensembl:ENST00000675331(transcript)|ensembl:ENST00000675390(transcript)|ensembl:ENST00000676098(transcript)|ensembl:ENST00000676188(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000235"(astral microtubule)|go:"GO:0000776"(kinetochore)|refseq:XP_016880188.1|refseq:XP_016880189.1|refseq:XP_016880190.1|dip:DIP-35691N|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001675"(acrosome assembly)|go:"GO:0001764"(neuron migration)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007097"(nuclear migration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007281"(germ cell development)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007611"(learning or memory)|go:"GO:0008017"(microtubule binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008201"(heparin binding)|go:"GO:0008247"(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:"GO:0009306"(protein secretion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0017145"(stem cell division)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0021540"(corpus callosum morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031514"(motile cilium)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0036035"(osteoclast development)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042249"(establishment of planar polarity of embryonic epithelium)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0045202"(synapse)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046469"(platelet activating factor metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0034452"(dynactin binding)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|mint:P43034|rcsb pdb:7MT1|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090102"(cochlea development)|go:"GO:0090176"(microtubule cytoskeleton organization involved in establishment of planar polarity)|go:"GO:0090724"(central region of growth cone)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR015943(WD40/YVTN repeat-like) - - - figure legend:Fig 2D.|comment:"Lis1 interacts with NudE (nde1) and the two important amino acid sites at positions 149 and 169 are required for this interaction."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2009/03/13 2014/10/16 rogid:711HNgfdXkDQEAEhRwa4DjKah5s10090 rogid:CgijDhrO703mGYXvJ44BgQJfVgM9606 intact-crc:C63951594C13E128|rigid:7b/s4gBnXTadoRnK4MD4SEw42yA false green fluorescent protein tag:n-n myc tag:n-n|mutation decreasing interaction:149-149|mutation decreasing interaction:169-169 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P43034 uniprotkb:Q9CZA6 intact:EBI-720620|uniprotkb:Q8WZ88|uniprotkb:Q8WZ89|uniprotkb:B2R7Q7|ensembl:ENSP00000380378|ensembl:ENSP00000501969|ensembl:ENSP00000502031|ensembl:ENSP00000502577|ensembl:ENSP00000502735|ensembl:ENSP00000502843 intact:EBI-309934|uniprotkb:Q3UBS6|uniprotkb:Q3UIC1|uniprotkb:Q9ERR0|ensembl:ENSMUSP00000023359 psi-mi:lis1_human(display_long)|uniprotkb:PAF acetylhydrolase 45 kDa subunit(gene name synonym)|uniprotkb:PAF-AH alpha(gene name synonym)|uniprotkb:Lissencephaly-1 protein(gene name synonym)|uniprotkb:PAFAH1B1(gene name)|psi-mi:PAFAH1B1(display_short)|uniprotkb:LIS1(gene name synonym)|uniprotkb:MDCR(gene name synonym)|uniprotkb:PAFAHA(gene name synonym)|uniprotkb:MDS(gene name synonym) psi-mi:nde1_mouse(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Feng et al. (2000) pubmed:11163258|imex:IM-19200 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2431137|imex:IM-19200-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000421.1|ensembl:ENSG00000007168(gene)|ensembl:ENST00000397195(transcript)|ensembl:ENST00000675202(transcript)|ensembl:ENST00000675331(transcript)|ensembl:ENST00000675390(transcript)|ensembl:ENST00000676098(transcript)|ensembl:ENST00000676188(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000235"(astral microtubule)|go:"GO:0000776"(kinetochore)|refseq:XP_016880188.1|refseq:XP_016880189.1|refseq:XP_016880190.1|dip:DIP-35691N|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001675"(acrosome assembly)|go:"GO:0001764"(neuron migration)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007097"(nuclear migration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007281"(germ cell development)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007611"(learning or memory)|go:"GO:0008017"(microtubule binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008201"(heparin binding)|go:"GO:0008247"(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:"GO:0009306"(protein secretion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0017145"(stem cell division)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0021540"(corpus callosum morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031514"(motile cilium)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0036035"(osteoclast development)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042249"(establishment of planar polarity of embryonic epithelium)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0045202"(synapse)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046469"(platelet activating factor metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0034452"(dynactin binding)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|mint:P43034|rcsb pdb:7MT1|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090102"(cochlea development)|go:"GO:0090176"(microtubule cytoskeleton organization involved in establishment of planar polarity)|go:"GO:0090724"(central region of growth cone)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR015943(WD40/YVTN repeat-like) refseq:NP_001107557.1|refseq:NP_075806.2|refseq:NP_001272432.1|refseq:NP_001272433.1|refseq:XP_011244302.1|ensembl:ENSMUSG00000022678(gene)|ensembl:ENSMUST00000023359(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9CZA6|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025|dip:DIP-54638N - - - figure legend:Fig 2D.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2009/03/13 2014/10/16 rogid:CgijDhrO703mGYXvJ44BgQJfVgM9606 rogid:711HNgfdXkDQEAEhRwa4DjKah5s10090 intact-crc:998FC679FADE6F39|rigid:7b/s4gBnXTadoRnK4MD4SEw42yA false green fluorescent protein tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9CZA6 uniprotkb:P63005 intact:EBI-309934|uniprotkb:Q3UBS6|uniprotkb:Q3UIC1|uniprotkb:Q9ERR0|ensembl:ENSMUSP00000023359 intact:EBI-917499|uniprotkb:O35592|uniprotkb:P43035|uniprotkb:P81692|uniprotkb:Q9R2A6|ensembl:ENSMUSP00000021091|ensembl:ENSMUSP00000099578 psi-mi:nde1_mouse(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym) psi-mi:lis1_mouse(display_long)|uniprotkb:PAF acetylhydrolase 45 kDa subunit(gene name synonym)|uniprotkb:PAF-AH alpha(gene name synonym)|uniprotkb:Lissencephaly-1 protein(gene name synonym)|uniprotkb:Pafah1b1(gene name)|psi-mi:Pafah1b1(display_short)|uniprotkb:Lis1(gene name synonym)|uniprotkb:Lis-1(gene name synonym)|uniprotkb:Pafaha(gene name synonym) psi-mi:"MI:0096"(pull down) Feng et al. (2000) pubmed:11163258|imex:IM-19200 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2431156|imex:IM-19200-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001107557.1|refseq:NP_075806.2|refseq:NP_001272432.1|refseq:NP_001272433.1|refseq:XP_011244302.1|ensembl:ENSMUSG00000022678(gene)|ensembl:ENSMUST00000023359(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9CZA6|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025|dip:DIP-54638N refseq:NP_038653.1|dip:DIP-29555N|ensembl:ENSMUSG00000020745(gene)|ensembl:ENSMUST00000021091(transcript)|ensembl:ENSMUST00000102520(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000235"(astral microtubule)|go:"GO:0000776"(kinetochore)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001675"(acrosome assembly)|go:"GO:0001764"(neuron migration)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007097"(nuclear migration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007281"(germ cell development)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007611"(learning or memory)|go:"GO:0008017"(microtubule binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008247"(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009306"(protein secretion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016477"(cell migration)|go:"GO:0017145"(stem cell division)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0021540"(corpus callosum morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031514"(motile cilium)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032420"(stereocilium)|go:"GO:0036035"(osteoclast development)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042249"(establishment of planar polarity of embryonic epithelium)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051130"(positive regulation of cellular component organization)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090102"(cochlea development)|go:"GO:0090176"(microtubule cytoskeleton organization involved in establishment of planar polarity)|go:"GO:0090724"(central region of growth cone)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|mint:P63005|rcsb pdb:1UUJ|rcsb pdb:1VYH|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025 - - - figure legend:Fig 2B.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/03/13 2014/10/16 rogid:711HNgfdXkDQEAEhRwa4DjKah5s10090 rogid:worzim1DpTldfv3SQdodqPmMozk10090 intact-crc:9A4BE5BF442BEC60|rigid:2TbAs7uBjKWQl0OQukSXiN03tfI false sufficient binding region:88-156|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-2431181 uniprotkb:Q9CZA6 - intact:EBI-309934|uniprotkb:Q3UBS6|uniprotkb:Q3UIC1|uniprotkb:Q9ERR0|ensembl:ENSMUSP00000023359 psi-mi:lis1_cerae_protein(display_short)|psi-mi:EBI-2431181(display_long) psi-mi:nde1_mouse(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Feng et al. (2000) pubmed:11163258|imex:IM-19200 taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2431184|imex:IM-19200-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001107557.1|refseq:NP_075806.2|refseq:NP_001272432.1|refseq:NP_001272433.1|refseq:XP_011244302.1|ensembl:ENSMUSG00000022678(gene)|ensembl:ENSMUST00000023359(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9CZA6|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025|dip:DIP-54638N - no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Similar to P63005 - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2009/03/13 2014/10/16 - rogid:711HNgfdXkDQEAEhRwa4DjKah5s10090 intact-crc:7570CC10735856F8 false - green fluorescent protein tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)