#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P46963 uniprotkb:P46962 intact:EBI-5241|uniprotkb:Q6LBS6|uniprotkb:D6W0H2|ensemblfungi:YML112W intact:EBI-5236|uniprotkb:D6VWG9|ensemblfungi:YJL006C psi-mi:ctk3_yeast(display_long)|uniprotkb:CTK3(gene name)|psi-mi:CTK3(display_short)|uniprotkb:YML112W(locus name)|uniprotkb:YM8339.07(orf name)|uniprotkb:CTD kinase subunit 3(gene name synonym)|uniprotkb:CTD kinase 32 kDa subunit(gene name synonym) psi-mi:ctk2_yeast(display_long)|uniprotkb:CTK2(gene name)|psi-mi:CTK2(display_short)|uniprotkb:YJL006C(locus name)|uniprotkb:J1390(orf name)|uniprotkb:CTD kinase subunit 2(gene name synonym)|uniprotkb:CTD kinase 38 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hautbergue et al. (2001) pubmed:11118453|imex:IM-20343 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2429513|imex:IM-20343-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013595.1|sgd:S000004580|dip:DIP-2106N|mint:P46963|ensemblfungi:YML112W(gene)|ensemblfungi:YML112W_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0071619"(phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|interpro:IPR024637|interpro:IPR042326|rcsb pdb:7JV7 refseq:NP_012528.1|sgd:S000003543|dip:DIP-2105N|mint:P46962|ensemblfungi:YJL006C(gene)|ensemblfungi:YJL006C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070692"(CTDK-1 complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR043198|rcsb pdb:7JV7|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-75955|reactome:R-SCE-9018519 - crc64:12F6D3F7181547ED - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/19 2014/10/16 rogid:4/8OqeRrS+55eRrdLGZ6z8M0EOA559292 rogid:NXQinB6zZUQR/mKhTNMq+5j6dP0559292 intact-crc:C6EF4CBA128F9E79|rigid:kpWRAklKZOfENzSIwRgyBMsxbuU false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P46963 uniprotkb:P46962 intact:EBI-5241|uniprotkb:Q6LBS6|uniprotkb:D6W0H2|ensemblfungi:YML112W intact:EBI-5236|uniprotkb:D6VWG9|ensemblfungi:YJL006C psi-mi:ctk3_yeast(display_long)|uniprotkb:CTK3(gene name)|psi-mi:CTK3(display_short)|uniprotkb:YML112W(locus name)|uniprotkb:YM8339.07(orf name)|uniprotkb:CTD kinase subunit 3(gene name synonym)|uniprotkb:CTD kinase 32 kDa subunit(gene name synonym) psi-mi:ctk2_yeast(display_long)|uniprotkb:CTK2(gene name)|psi-mi:CTK2(display_short)|uniprotkb:YJL006C(locus name)|uniprotkb:J1390(orf name)|uniprotkb:CTD kinase subunit 2(gene name synonym)|uniprotkb:CTD kinase 38 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hautbergue et al. (2001) pubmed:11118453|imex:IM-20343 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2429526|imex:IM-20343-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013595.1|sgd:S000004580|dip:DIP-2106N|mint:P46963|ensemblfungi:YML112W(gene)|ensemblfungi:YML112W_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0071619"(phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|interpro:IPR024637|interpro:IPR042326|rcsb pdb:7JV7 refseq:NP_012528.1|sgd:S000003543|dip:DIP-2105N|mint:P46962|ensemblfungi:YJL006C(gene)|ensemblfungi:YJL006C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070692"(CTDK-1 complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR043198|rcsb pdb:7JV7|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-75955|reactome:R-SCE-9018519 - crc64:12F6D3F7181547ED - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/08/19 2014/10/16 rogid:4/8OqeRrS+55eRrdLGZ6z8M0EOA559292 rogid:NXQinB6zZUQR/mKhTNMq+5j6dP0559292 intact-crc:693CF415C002BE76|rigid:kpWRAklKZOfENzSIwRgyBMsxbuU false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P46962 uniprotkb:P46963 intact:EBI-5236|uniprotkb:D6VWG9|ensemblfungi:YJL006C intact:EBI-5241|uniprotkb:Q6LBS6|uniprotkb:D6W0H2|ensemblfungi:YML112W psi-mi:ctk2_yeast(display_long)|uniprotkb:CTK2(gene name)|psi-mi:CTK2(display_short)|uniprotkb:YJL006C(locus name)|uniprotkb:J1390(orf name)|uniprotkb:CTD kinase subunit 2(gene name synonym)|uniprotkb:CTD kinase 38 kDa subunit(gene name synonym) psi-mi:ctk3_yeast(display_long)|uniprotkb:CTK3(gene name)|psi-mi:CTK3(display_short)|uniprotkb:YML112W(locus name)|uniprotkb:YM8339.07(orf name)|uniprotkb:CTD kinase subunit 3(gene name synonym)|uniprotkb:CTD kinase 32 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hautbergue et al. (2001) pubmed:11118453|imex:IM-20343 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2429551|imex:IM-20343-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012528.1|sgd:S000003543|dip:DIP-2105N|mint:P46962|ensemblfungi:YJL006C(gene)|ensemblfungi:YJL006C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070692"(CTDK-1 complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR043198|rcsb pdb:7JV7|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-75955|reactome:R-SCE-9018519 refseq:NP_013595.1|sgd:S000004580|dip:DIP-2106N|mint:P46963|ensemblfungi:YML112W(gene)|ensemblfungi:YML112W_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0071619"(phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|interpro:IPR024637|interpro:IPR042326|rcsb pdb:7JV7 - - crc64:12F6D3F7181547ED figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/08/19 2014/10/16 rogid:NXQinB6zZUQR/mKhTNMq+5j6dP0559292 rogid:4/8OqeRrS+55eRrdLGZ6z8M0EOA559292 intact-crc:C78CD428B96D7CE0|rigid:kpWRAklKZOfENzSIwRgyBMsxbuU false 35s radiolabel:?-?|ha tag:?-? myc tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P46963 uniprotkb:P46962 intact:EBI-5241|uniprotkb:Q6LBS6|uniprotkb:D6W0H2|ensemblfungi:YML112W intact:EBI-5236|uniprotkb:D6VWG9|ensemblfungi:YJL006C psi-mi:ctk3_yeast(display_long)|uniprotkb:CTK3(gene name)|psi-mi:CTK3(display_short)|uniprotkb:YML112W(locus name)|uniprotkb:YM8339.07(orf name)|uniprotkb:CTD kinase subunit 3(gene name synonym)|uniprotkb:CTD kinase 32 kDa subunit(gene name synonym) psi-mi:ctk2_yeast(display_long)|uniprotkb:CTK2(gene name)|psi-mi:CTK2(display_short)|uniprotkb:YJL006C(locus name)|uniprotkb:J1390(orf name)|uniprotkb:CTD kinase subunit 2(gene name synonym)|uniprotkb:CTD kinase 38 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hautbergue et al. (2001) pubmed:11118453|imex:IM-20343 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2429576|imex:IM-20343-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013595.1|sgd:S000004580|dip:DIP-2106N|mint:P46963|ensemblfungi:YML112W(gene)|ensemblfungi:YML112W_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0071619"(phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|interpro:IPR024637|interpro:IPR042326|rcsb pdb:7JV7 refseq:NP_012528.1|sgd:S000003543|dip:DIP-2105N|mint:P46962|ensemblfungi:YJL006C(gene)|ensemblfungi:YJL006C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070692"(CTDK-1 complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR043198|rcsb pdb:7JV7|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-75955|reactome:R-SCE-9018519 - crc64:12F6D3F7181547ED - figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/08/19 2014/10/16 rogid:4/8OqeRrS+55eRrdLGZ6z8M0EOA559292 rogid:NXQinB6zZUQR/mKhTNMq+5j6dP0559292 intact-crc:9F53C42542D8C6B6|rigid:kpWRAklKZOfENzSIwRgyBMsxbuU false myc tag:?-? 35s radiolabel:?-?|ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P46962 uniprotkb:P46963 intact:EBI-5236|uniprotkb:D6VWG9|ensemblfungi:YJL006C intact:EBI-5241|uniprotkb:Q6LBS6|uniprotkb:D6W0H2|ensemblfungi:YML112W psi-mi:ctk2_yeast(display_long)|uniprotkb:CTK2(gene name)|psi-mi:CTK2(display_short)|uniprotkb:YJL006C(locus name)|uniprotkb:J1390(orf name)|uniprotkb:CTD kinase subunit 2(gene name synonym)|uniprotkb:CTD kinase 38 kDa subunit(gene name synonym) psi-mi:ctk3_yeast(display_long)|uniprotkb:CTK3(gene name)|psi-mi:CTK3(display_short)|uniprotkb:YML112W(locus name)|uniprotkb:YM8339.07(orf name)|uniprotkb:CTD kinase subunit 3(gene name synonym)|uniprotkb:CTD kinase 32 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hautbergue et al. (2001) pubmed:11118453|imex:IM-20343 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2429629|imex:IM-20343-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012528.1|sgd:S000003543|dip:DIP-2105N|mint:P46962|ensemblfungi:YJL006C(gene)|ensemblfungi:YJL006C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070692"(CTDK-1 complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR043198|rcsb pdb:7JV7|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-75955|reactome:R-SCE-9018519 refseq:NP_013595.1|sgd:S000004580|dip:DIP-2106N|mint:P46963|ensemblfungi:YML112W(gene)|ensemblfungi:YML112W_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0071619"(phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|interpro:IPR024637|interpro:IPR042326|rcsb pdb:7JV7 - - crc64:12F6D3F7181547ED figure legend:Fig. 6C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/08/19 2014/10/16 rogid:NXQinB6zZUQR/mKhTNMq+5j6dP0559292 rogid:4/8OqeRrS+55eRrdLGZ6z8M0EOA559292 intact-crc:212B44009EE830C2|rigid:kpWRAklKZOfENzSIwRgyBMsxbuU false myc tag:?-? ha tag:?-?|necessary binding region:246-296 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P46963 uniprotkb:Q03957 intact:EBI-5241|uniprotkb:Q6LBS6|uniprotkb:D6W0H2|ensemblfungi:YML112W intact:EBI-5230|uniprotkb:D6VX57|ensemblfungi:YKL139W psi-mi:ctk3_yeast(display_long)|uniprotkb:CTK3(gene name)|psi-mi:CTK3(display_short)|uniprotkb:YML112W(locus name)|uniprotkb:YM8339.07(orf name)|uniprotkb:CTD kinase subunit 3(gene name synonym)|uniprotkb:CTD kinase 32 kDa subunit(gene name synonym) psi-mi:ctk1_yeast(display_long)|uniprotkb:CTK1(gene name)|psi-mi:CTK1(display_short)|uniprotkb:CTD kinase subunit 1(gene name synonym)|uniprotkb:CTD kinase 58 kDa subunit(gene name synonym)|uniprotkb:YKL139W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hautbergue et al. (2001) pubmed:11118453|imex:IM-20343 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2429654|imex:IM-20343-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013595.1|sgd:S000004580|dip:DIP-2106N|mint:P46963|ensemblfungi:YML112W(gene)|ensemblfungi:YML112W_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0071619"(phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|interpro:IPR024637|interpro:IPR042326|rcsb pdb:7JV7 refseq:NP_012783.1|sgd:S000001622|dip:DIP-6631N|mint:Q03957|ensemblfungi:YKL139W(gene)|ensemblfungi:YKL139W_mRNA(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006413"(translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030332"(cyclin binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:7JV7 - crc64:12F6D3F7181547ED crc64:9862EB10FD476F6B figure legend:Figs. 6D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/08/19 2014/10/16 rogid:4/8OqeRrS+55eRrdLGZ6z8M0EOA559292 rogid:UAGFPi65iZmt4poaGbS4AKLhtkI559292 intact-crc:BAD9BCE62F8C4D63|rigid:Xq+4sFtmXQydW2RESgpWLazN898 false necessary binding region:247-296|ha tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P46962 uniprotkb:Q03957 intact:EBI-5236|uniprotkb:D6VWG9|ensemblfungi:YJL006C intact:EBI-5230|uniprotkb:D6VX57|ensemblfungi:YKL139W psi-mi:ctk2_yeast(display_long)|uniprotkb:CTK2(gene name)|psi-mi:CTK2(display_short)|uniprotkb:YJL006C(locus name)|uniprotkb:J1390(orf name)|uniprotkb:CTD kinase subunit 2(gene name synonym)|uniprotkb:CTD kinase 38 kDa subunit(gene name synonym) psi-mi:ctk1_yeast(display_long)|uniprotkb:CTK1(gene name)|psi-mi:CTK1(display_short)|uniprotkb:CTD kinase subunit 1(gene name synonym)|uniprotkb:CTD kinase 58 kDa subunit(gene name synonym)|uniprotkb:YKL139W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hautbergue et al. (2001) pubmed:11118453|imex:IM-20343 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2429681|imex:IM-20343-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012528.1|sgd:S000003543|dip:DIP-2105N|mint:P46962|ensemblfungi:YJL006C(gene)|ensemblfungi:YJL006C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070692"(CTDK-1 complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR043198|rcsb pdb:7JV7|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-75955|reactome:R-SCE-9018519 refseq:NP_012783.1|sgd:S000001622|dip:DIP-6631N|mint:Q03957|ensemblfungi:YKL139W(gene)|ensemblfungi:YKL139W_mRNA(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006413"(translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030332"(cyclin binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:7JV7 - - crc64:9862EB10FD476F6B figure legend:Fig. 7A|comment:Myc-tagged proteins were differentiated by molecular weight.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/08/19 2014/10/16 rogid:NXQinB6zZUQR/mKhTNMq+5j6dP0559292 rogid:UAGFPi65iZmt4poaGbS4AKLhtkI559292 intact-crc:26876A344B61B105|rigid:UiGkxt/7OrIYEyRW6Tv8ipELC8Y false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P46962 uniprotkb:P46963 intact:EBI-5236|uniprotkb:D6VWG9|ensemblfungi:YJL006C intact:EBI-5241|uniprotkb:Q6LBS6|uniprotkb:D6W0H2|ensemblfungi:YML112W psi-mi:ctk2_yeast(display_long)|uniprotkb:CTK2(gene name)|psi-mi:CTK2(display_short)|uniprotkb:YJL006C(locus name)|uniprotkb:J1390(orf name)|uniprotkb:CTD kinase subunit 2(gene name synonym)|uniprotkb:CTD kinase 38 kDa subunit(gene name synonym) psi-mi:ctk3_yeast(display_long)|uniprotkb:CTK3(gene name)|psi-mi:CTK3(display_short)|uniprotkb:YML112W(locus name)|uniprotkb:YM8339.07(orf name)|uniprotkb:CTD kinase subunit 3(gene name synonym)|uniprotkb:CTD kinase 32 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hautbergue et al. (2001) pubmed:11118453|imex:IM-20343 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2429681|imex:IM-20343-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012528.1|sgd:S000003543|dip:DIP-2105N|mint:P46962|ensemblfungi:YJL006C(gene)|ensemblfungi:YJL006C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070692"(CTDK-1 complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR043198|rcsb pdb:7JV7|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-75955|reactome:R-SCE-9018519 refseq:NP_013595.1|sgd:S000004580|dip:DIP-2106N|mint:P46963|ensemblfungi:YML112W(gene)|ensemblfungi:YML112W_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0071619"(phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|interpro:IPR024637|interpro:IPR042326|rcsb pdb:7JV7 - - crc64:12F6D3F7181547ED figure legend:Fig. 7A|comment:Myc-tagged proteins were differentiated by molecular weight.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/08/19 2014/10/16 rogid:NXQinB6zZUQR/mKhTNMq+5j6dP0559292 rogid:4/8OqeRrS+55eRrdLGZ6z8M0EOA559292 intact-crc:26876A344B61B105|rigid:UiGkxt/7OrIYEyRW6Tv8ipELC8Y false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P46962 uniprotkb:Q03957 intact:EBI-5236|uniprotkb:D6VWG9|ensemblfungi:YJL006C intact:EBI-5230|uniprotkb:D6VX57|ensemblfungi:YKL139W psi-mi:ctk2_yeast(display_long)|uniprotkb:CTK2(gene name)|psi-mi:CTK2(display_short)|uniprotkb:YJL006C(locus name)|uniprotkb:J1390(orf name)|uniprotkb:CTD kinase subunit 2(gene name synonym)|uniprotkb:CTD kinase 38 kDa subunit(gene name synonym) psi-mi:ctk1_yeast(display_long)|uniprotkb:CTK1(gene name)|psi-mi:CTK1(display_short)|uniprotkb:CTD kinase subunit 1(gene name synonym)|uniprotkb:CTD kinase 58 kDa subunit(gene name synonym)|uniprotkb:YKL139W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hautbergue et al. (2001) pubmed:11118453|imex:IM-20343 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2429704|imex:IM-20343-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012528.1|sgd:S000003543|dip:DIP-2105N|mint:P46962|ensemblfungi:YJL006C(gene)|ensemblfungi:YJL006C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070692"(CTDK-1 complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR043198|rcsb pdb:7JV7|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-75955|reactome:R-SCE-9018519 refseq:NP_012783.1|sgd:S000001622|dip:DIP-6631N|mint:Q03957|ensemblfungi:YKL139W(gene)|ensemblfungi:YKL139W_mRNA(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006413"(translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030332"(cyclin binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:7JV7 - - crc64:9862EB10FD476F6B figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/08/19 2014/10/16 rogid:NXQinB6zZUQR/mKhTNMq+5j6dP0559292 rogid:UAGFPi65iZmt4poaGbS4AKLhtkI559292 intact-crc:BF096D6C347CD50D|rigid:jAkYRM5yqp5R3yUbqQBLUkEw7Bc false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P46963 uniprotkb:P46962 intact:EBI-5241|uniprotkb:Q6LBS6|uniprotkb:D6W0H2|ensemblfungi:YML112W intact:EBI-5236|uniprotkb:D6VWG9|ensemblfungi:YJL006C psi-mi:ctk3_yeast(display_long)|uniprotkb:CTK3(gene name)|psi-mi:CTK3(display_short)|uniprotkb:YML112W(locus name)|uniprotkb:YM8339.07(orf name)|uniprotkb:CTD kinase subunit 3(gene name synonym)|uniprotkb:CTD kinase 32 kDa subunit(gene name synonym) psi-mi:ctk2_yeast(display_long)|uniprotkb:CTK2(gene name)|psi-mi:CTK2(display_short)|uniprotkb:YJL006C(locus name)|uniprotkb:J1390(orf name)|uniprotkb:CTD kinase subunit 2(gene name synonym)|uniprotkb:CTD kinase 38 kDa subunit(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Hautbergue et al. (2001) pubmed:11118453|imex:IM-20343 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2429607|imex:IM-20343-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013595.1|sgd:S000004580|dip:DIP-2106N|mint:P46963|ensemblfungi:YML112W(gene)|ensemblfungi:YML112W_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0071619"(phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|interpro:IPR024637|interpro:IPR042326|rcsb pdb:7JV7 refseq:NP_012528.1|sgd:S000003543|dip:DIP-2105N|mint:P46962|ensemblfungi:YJL006C(gene)|ensemblfungi:YJL006C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070692"(CTDK-1 complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR043198|rcsb pdb:7JV7|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-75955|reactome:R-SCE-9018519 - crc64:12F6D3F7181547ED - figure legend:Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/08/19 2014/10/16 rogid:4/8OqeRrS+55eRrdLGZ6z8M0EOA559292 rogid:NXQinB6zZUQR/mKhTNMq+5j6dP0559292 intact-crc:39D0B6AA24A08E32|rigid:kpWRAklKZOfENzSIwRgyBMsxbuU false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q03957 uniprotkb:P46962 intact:EBI-5230|uniprotkb:D6VX57|ensemblfungi:YKL139W intact:EBI-5236|uniprotkb:D6VWG9|ensemblfungi:YJL006C psi-mi:ctk1_yeast(display_long)|uniprotkb:CTK1(gene name)|psi-mi:CTK1(display_short)|uniprotkb:CTD kinase subunit 1(gene name synonym)|uniprotkb:CTD kinase 58 kDa subunit(gene name synonym)|uniprotkb:YKL139W(locus name) psi-mi:ctk2_yeast(display_long)|uniprotkb:CTK2(gene name)|psi-mi:CTK2(display_short)|uniprotkb:YJL006C(locus name)|uniprotkb:J1390(orf name)|uniprotkb:CTD kinase subunit 2(gene name synonym)|uniprotkb:CTD kinase 38 kDa subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Hautbergue et al. (2001) pubmed:11118453|imex:IM-20343 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2429742|imex:IM-20343-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012783.1|sgd:S000001622|dip:DIP-6631N|mint:Q03957|ensemblfungi:YKL139W(gene)|ensemblfungi:YKL139W_mRNA(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006413"(translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030332"(cyclin binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:7JV7 refseq:NP_012528.1|sgd:S000003543|dip:DIP-2105N|mint:P46962|ensemblfungi:YJL006C(gene)|ensemblfungi:YJL006C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070692"(CTDK-1 complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR043198|rcsb pdb:7JV7|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-75955|reactome:R-SCE-9018519 - crc64:9862EB10FD476F6B - figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2009/08/19 2014/10/16 rogid:UAGFPi65iZmt4poaGbS4AKLhtkI559292 rogid:NXQinB6zZUQR/mKhTNMq+5j6dP0559292 intact-crc:E4F0B6B9EAD12A57|rigid:UiGkxt/7OrIYEyRW6Tv8ipELC8Y false ha tag:?-?|his tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q03957 uniprotkb:P46963 intact:EBI-5230|uniprotkb:D6VX57|ensemblfungi:YKL139W intact:EBI-5241|uniprotkb:Q6LBS6|uniprotkb:D6W0H2|ensemblfungi:YML112W psi-mi:ctk1_yeast(display_long)|uniprotkb:CTK1(gene name)|psi-mi:CTK1(display_short)|uniprotkb:CTD kinase subunit 1(gene name synonym)|uniprotkb:CTD kinase 58 kDa subunit(gene name synonym)|uniprotkb:YKL139W(locus name) psi-mi:ctk3_yeast(display_long)|uniprotkb:CTK3(gene name)|psi-mi:CTK3(display_short)|uniprotkb:YML112W(locus name)|uniprotkb:YM8339.07(orf name)|uniprotkb:CTD kinase subunit 3(gene name synonym)|uniprotkb:CTD kinase 32 kDa subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Hautbergue et al. (2001) pubmed:11118453|imex:IM-20343 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2429742|imex:IM-20343-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012783.1|sgd:S000001622|dip:DIP-6631N|mint:Q03957|ensemblfungi:YKL139W(gene)|ensemblfungi:YKL139W_mRNA(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006413"(translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030332"(cyclin binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:7JV7 refseq:NP_013595.1|sgd:S000004580|dip:DIP-2106N|mint:P46963|ensemblfungi:YML112W(gene)|ensemblfungi:YML112W_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0071619"(phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|interpro:IPR024637|interpro:IPR042326|rcsb pdb:7JV7 - crc64:9862EB10FD476F6B crc64:12F6D3F7181547ED figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2009/08/19 2014/10/16 rogid:UAGFPi65iZmt4poaGbS4AKLhtkI559292 rogid:4/8OqeRrS+55eRrdLGZ6z8M0EOA559292 intact-crc:E4F0B6B9EAD12A57|rigid:UiGkxt/7OrIYEyRW6Tv8ipELC8Y false ha tag:?-?|his tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P46962 uniprotkb:Q03957 intact:EBI-5236|uniprotkb:D6VWG9|ensemblfungi:YJL006C intact:EBI-5230|uniprotkb:D6VX57|ensemblfungi:YKL139W psi-mi:ctk2_yeast(display_long)|uniprotkb:CTK2(gene name)|psi-mi:CTK2(display_short)|uniprotkb:YJL006C(locus name)|uniprotkb:J1390(orf name)|uniprotkb:CTD kinase subunit 2(gene name synonym)|uniprotkb:CTD kinase 38 kDa subunit(gene name synonym) psi-mi:ctk1_yeast(display_long)|uniprotkb:CTK1(gene name)|psi-mi:CTK1(display_short)|uniprotkb:CTD kinase subunit 1(gene name synonym)|uniprotkb:CTD kinase 58 kDa subunit(gene name synonym)|uniprotkb:YKL139W(locus name) psi-mi:"MI:0096"(pull down) Hautbergue et al. (2001) pubmed:11118453|imex:IM-20343 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2429758|imex:IM-20343-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012528.1|sgd:S000003543|dip:DIP-2105N|mint:P46962|ensemblfungi:YJL006C(gene)|ensemblfungi:YJL006C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070692"(CTDK-1 complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR043198|rcsb pdb:7JV7|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-75955|reactome:R-SCE-9018519 refseq:NP_012783.1|sgd:S000001622|dip:DIP-6631N|mint:Q03957|ensemblfungi:YKL139W(gene)|ensemblfungi:YKL139W_mRNA(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006413"(translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030332"(cyclin binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:7JV7 - - crc64:9862EB10FD476F6B figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2009/08/19 2014/10/16 rogid:NXQinB6zZUQR/mKhTNMq+5j6dP0559292 rogid:UAGFPi65iZmt4poaGbS4AKLhtkI559292 intact-crc:4F687C27BFD5880C|rigid:jAkYRM5yqp5R3yUbqQBLUkEw7Bc false ha tag:?-? ha tag:?-?|his tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P46963 uniprotkb:Q03957 intact:EBI-5241|uniprotkb:Q6LBS6|uniprotkb:D6W0H2|ensemblfungi:YML112W intact:EBI-5230|uniprotkb:D6VX57|ensemblfungi:YKL139W psi-mi:ctk3_yeast(display_long)|uniprotkb:CTK3(gene name)|psi-mi:CTK3(display_short)|uniprotkb:YML112W(locus name)|uniprotkb:YM8339.07(orf name)|uniprotkb:CTD kinase subunit 3(gene name synonym)|uniprotkb:CTD kinase 32 kDa subunit(gene name synonym) psi-mi:ctk1_yeast(display_long)|uniprotkb:CTK1(gene name)|psi-mi:CTK1(display_short)|uniprotkb:CTD kinase subunit 1(gene name synonym)|uniprotkb:CTD kinase 58 kDa subunit(gene name synonym)|uniprotkb:YKL139W(locus name) psi-mi:"MI:0096"(pull down) Hautbergue et al. (2001) pubmed:11118453|imex:IM-20343 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2429769|imex:IM-20343-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013595.1|sgd:S000004580|dip:DIP-2106N|mint:P46963|ensemblfungi:YML112W(gene)|ensemblfungi:YML112W_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0071619"(phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|interpro:IPR024637|interpro:IPR042326|rcsb pdb:7JV7 refseq:NP_012783.1|sgd:S000001622|dip:DIP-6631N|mint:Q03957|ensemblfungi:YKL139W(gene)|ensemblfungi:YKL139W_mRNA(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006413"(translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030332"(cyclin binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:7JV7 - crc64:12F6D3F7181547ED crc64:9862EB10FD476F6B figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2009/08/19 2014/10/16 rogid:4/8OqeRrS+55eRrdLGZ6z8M0EOA559292 rogid:UAGFPi65iZmt4poaGbS4AKLhtkI559292 intact-crc:C7C5FFFF90E7B0DC|rigid:Xq+4sFtmXQydW2RESgpWLazN898 false ha tag:?-? ha tag:?-?|his tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q03957 uniprotkb:P46962 intact:EBI-5230|uniprotkb:D6VX57|ensemblfungi:YKL139W intact:EBI-5236|uniprotkb:D6VWG9|ensemblfungi:YJL006C psi-mi:ctk1_yeast(display_long)|uniprotkb:CTK1(gene name)|psi-mi:CTK1(display_short)|uniprotkb:CTD kinase subunit 1(gene name synonym)|uniprotkb:CTD kinase 58 kDa subunit(gene name synonym)|uniprotkb:YKL139W(locus name) psi-mi:ctk2_yeast(display_long)|uniprotkb:CTK2(gene name)|psi-mi:CTK2(display_short)|uniprotkb:YJL006C(locus name)|uniprotkb:J1390(orf name)|uniprotkb:CTD kinase subunit 2(gene name synonym)|uniprotkb:CTD kinase 38 kDa subunit(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Hautbergue et al. (2001) pubmed:11118453|imex:IM-20343 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2429788|imex:IM-20343-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012783.1|sgd:S000001622|dip:DIP-6631N|mint:Q03957|ensemblfungi:YKL139W(gene)|ensemblfungi:YKL139W_mRNA(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006413"(translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030332"(cyclin binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:7JV7 refseq:NP_012528.1|sgd:S000003543|dip:DIP-2105N|mint:P46962|ensemblfungi:YJL006C(gene)|ensemblfungi:YJL006C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070692"(CTDK-1 complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR043198|rcsb pdb:7JV7|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-75955|reactome:R-SCE-9018519 go:"GO:0006468"(protein phosphorylation) crc64:9862EB10FD476F6B - figure legend:Fig. 7D|caution:Exact coordinates of the c-terminal domain of RPB1 not given in the text.|resulting-ptm:"Phosphorylation of RPB1 (P04050)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/08/19 2014/10/16 rogid:UAGFPi65iZmt4poaGbS4AKLhtkI559292 rogid:NXQinB6zZUQR/mKhTNMq+5j6dP0559292 intact-crc:8B66717C7DEDFC39|rigid:iBS9+a9oJTxi0uqzB9Dg8XlPd5g false ha tag:?-?|his tag:?-? ha tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q03957 uniprotkb:P46963 intact:EBI-5230|uniprotkb:D6VX57|ensemblfungi:YKL139W intact:EBI-5241|uniprotkb:Q6LBS6|uniprotkb:D6W0H2|ensemblfungi:YML112W psi-mi:ctk1_yeast(display_long)|uniprotkb:CTK1(gene name)|psi-mi:CTK1(display_short)|uniprotkb:CTD kinase subunit 1(gene name synonym)|uniprotkb:CTD kinase 58 kDa subunit(gene name synonym)|uniprotkb:YKL139W(locus name) psi-mi:ctk3_yeast(display_long)|uniprotkb:CTK3(gene name)|psi-mi:CTK3(display_short)|uniprotkb:YML112W(locus name)|uniprotkb:YM8339.07(orf name)|uniprotkb:CTD kinase subunit 3(gene name synonym)|uniprotkb:CTD kinase 32 kDa subunit(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Hautbergue et al. (2001) pubmed:11118453|imex:IM-20343 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2429788|imex:IM-20343-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012783.1|sgd:S000001622|dip:DIP-6631N|mint:Q03957|ensemblfungi:YKL139W(gene)|ensemblfungi:YKL139W_mRNA(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006413"(translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030332"(cyclin binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:7JV7 refseq:NP_013595.1|sgd:S000004580|dip:DIP-2106N|mint:P46963|ensemblfungi:YML112W(gene)|ensemblfungi:YML112W_mRNA(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0071619"(phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|interpro:IPR024637|interpro:IPR042326|rcsb pdb:7JV7 go:"GO:0006468"(protein phosphorylation) crc64:9862EB10FD476F6B crc64:12F6D3F7181547ED figure legend:Fig. 7D|caution:Exact coordinates of the c-terminal domain of RPB1 not given in the text.|resulting-ptm:"Phosphorylation of RPB1 (P04050)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/08/19 2014/10/16 rogid:UAGFPi65iZmt4poaGbS4AKLhtkI559292 rogid:4/8OqeRrS+55eRrdLGZ6z8M0EOA559292 intact-crc:8B66717C7DEDFC39|rigid:iBS9+a9oJTxi0uqzB9Dg8XlPd5g false ha tag:?-?|his tag:?-? ha tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q03957 uniprotkb:P04050 intact:EBI-5230|uniprotkb:D6VX57|ensemblfungi:YKL139W intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C psi-mi:ctk1_yeast(display_long)|uniprotkb:CTK1(gene name)|psi-mi:CTK1(display_short)|uniprotkb:CTD kinase subunit 1(gene name synonym)|uniprotkb:CTD kinase 58 kDa subunit(gene name synonym)|uniprotkb:YKL139W(locus name) psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Hautbergue et al. (2001) pubmed:11118453|imex:IM-20343 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2429788|imex:IM-20343-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012783.1|sgd:S000001622|dip:DIP-6631N|mint:Q03957|ensemblfungi:YKL139W(gene)|ensemblfungi:YKL139W_mRNA(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006413"(translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030332"(cyclin binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0070692"(CTDK-1 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:7JV7 refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519 go:"GO:0006468"(protein phosphorylation) crc64:9862EB10FD476F6B crc64:A45C1360FF99F968 figure legend:Fig. 7D|caution:Exact coordinates of the c-terminal domain of RPB1 not given in the text.|resulting-ptm:"Phosphorylation of RPB1 (P04050)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/08/19 2014/10/16 rogid:UAGFPi65iZmt4poaGbS4AKLhtkI559292 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 intact-crc:8B66717C7DEDFC39|rigid:iBS9+a9oJTxi0uqzB9Dg8XlPd5g false ha tag:?-?|his tag:?-? glutathione s tranferase tag:?-?|sufficient binding region:?-1733 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)