#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P16664 uniprotkb:P40395 intact:EBI-15080|uniprotkb:Q03915|uniprotkb:D6VSC0|ensemblfungi:YDR137W intact:EBI-15183|uniprotkb:D6VY42|ensemblfungi:YLR039C psi-mi:rgp1_yeast(display_long)|uniprotkb:RGP1(gene name)|psi-mi:RGP1(display_short)|uniprotkb:Reduced growth phenotype protein 1(gene name synonym)|uniprotkb:YD9302.13(orf name)|uniprotkb:YDR137W(locus name) psi-mi:ric1_yeast(display_long)|uniprotkb:RIC1(gene name)|psi-mi:RIC1(display_short)|uniprotkb:Ribosome control protein 1(gene name synonym)|uniprotkb:YLR039C(locus name)|uniprotkb:Protein RIC1(gene name synonym) psi-mi:"MI:0096"(pull down) Siniossoglou et al. (2000) pubmed:10990452|imex:IM-18948 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2256636|imex:IM-18948-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010421.1|sgd:S000002544|ensemblfungi:YDR137W(gene)|ensemblfungi:YDR137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0034066"(Ric1-Rgp1 guanyl-nucleotide exchange factor complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0051301"(cell division)|interpro:IPR014848(Rgp1)|reactome:R-SCE-6811440|reactome:R-SCE-8876198|dip:DIP-6486N|mint:P16664 refseq:NP_013140.1|sgd:S000004029|ensemblfungi:YLR039C(gene)|ensemblfungi:YLR039C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0034066"(Ric1-Rgp1 guanyl-nucleotide exchange factor complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR009771(Protein of unknown function DUF1339)|interpro:IPR040096|reactome:R-SCE-6811440|reactome:R-SCE-8876198|dip:DIP-2564N|mint:P40395 - crc64:4A3B311ED90ED14A crc64:2368616B67AEAD31 figure legend:Figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/02/17 2014/10/16 rogid:dO3vxD0q0ky4m2en1jsrqIkjaUs559292 rogid:m6o0B5KQhR3rrpM28RYIrAvej1k559292 intact-crc:CBF5C17120EF8131|rigid:bhUcSeoA4jSxMczftCAIKbaB8M4 false protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P40395 uniprotkb:P16664 intact:EBI-15183|uniprotkb:D6VY42|ensemblfungi:YLR039C intact:EBI-15080|uniprotkb:Q03915|uniprotkb:D6VSC0|ensemblfungi:YDR137W psi-mi:ric1_yeast(display_long)|uniprotkb:RIC1(gene name)|psi-mi:RIC1(display_short)|uniprotkb:Ribosome control protein 1(gene name synonym)|uniprotkb:YLR039C(locus name)|uniprotkb:Protein RIC1(gene name synonym) psi-mi:rgp1_yeast(display_long)|uniprotkb:RGP1(gene name)|psi-mi:RGP1(display_short)|uniprotkb:Reduced growth phenotype protein 1(gene name synonym)|uniprotkb:YD9302.13(orf name)|uniprotkb:YDR137W(locus name) psi-mi:"MI:0096"(pull down) Siniossoglou et al. (2000) pubmed:10990452|imex:IM-18948 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2256652|imex:IM-18948-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013140.1|sgd:S000004029|ensemblfungi:YLR039C(gene)|ensemblfungi:YLR039C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0034066"(Ric1-Rgp1 guanyl-nucleotide exchange factor complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR009771(Protein of unknown function DUF1339)|interpro:IPR040096|reactome:R-SCE-6811440|reactome:R-SCE-8876198|dip:DIP-2564N|mint:P40395 refseq:NP_010421.1|sgd:S000002544|ensemblfungi:YDR137W(gene)|ensemblfungi:YDR137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0034066"(Ric1-Rgp1 guanyl-nucleotide exchange factor complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0051301"(cell division)|interpro:IPR014848(Rgp1)|reactome:R-SCE-6811440|reactome:R-SCE-8876198|dip:DIP-6486N|mint:P16664 - crc64:2368616B67AEAD31 crc64:4A3B311ED90ED14A figure legend:Figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/02/17 2014/10/16 rogid:m6o0B5KQhR3rrpM28RYIrAvej1k559292 rogid:dO3vxD0q0ky4m2en1jsrqIkjaUs559292 intact-crc:59579725BBF1EDF8|rigid:bhUcSeoA4jSxMczftCAIKbaB8M4 false protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q99260 uniprotkb:P40395 intact:EBI-29503|uniprotkb:D6VYQ8|ensemblfungi:YLR262C intact:EBI-15183|uniprotkb:D6VY42|ensemblfungi:YLR039C psi-mi:ypt6_yeast(display_long)|uniprotkb:L8479.11(orf name)|uniprotkb:YLR262C(locus name)|uniprotkb:YPT6(gene name)|psi-mi:YPT6(display_short) psi-mi:ric1_yeast(display_long)|uniprotkb:RIC1(gene name)|psi-mi:RIC1(display_short)|uniprotkb:Ribosome control protein 1(gene name synonym)|uniprotkb:YLR039C(locus name)|uniprotkb:Protein RIC1(gene name synonym) psi-mi:"MI:0096"(pull down) Siniossoglou et al. (2000) pubmed:10990452|imex:IM-18948 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2256670|imex:IM-18948-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013363.1|sgd:S000004252|dip:DIP-5577N|mint:Q99260|ensemblfungi:YLR262C(gene)|ensemblfungi:YLR262C_mRNA(transcript)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-SCE-6798695|reactome:R-SCE-6811440|reactome:R-SCE-8873719|reactome:R-SCE-8876198 refseq:NP_013140.1|sgd:S000004029|ensemblfungi:YLR039C(gene)|ensemblfungi:YLR039C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0034066"(Ric1-Rgp1 guanyl-nucleotide exchange factor complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR009771(Protein of unknown function DUF1339)|interpro:IPR040096|reactome:R-SCE-6811440|reactome:R-SCE-8876198|dip:DIP-2564N|mint:P40395 - crc64:A8E6211FF24FAE0B crc64:2368616B67AEAD31 figure legend:Figure 3|antagonist:GTP|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/02/17 2014/10/16 rogid:J/SeVhLd4mnvD5QEdkpsXWUH1rU559292 rogid:m6o0B5KQhR3rrpM28RYIrAvej1k559292 intact-crc:F1C148CC656D4A50|rigid:UucHdgn94UrlagycZGxHbGOBa7Q false protein a tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q99260 uniprotkb:P16664 intact:EBI-29503|uniprotkb:D6VYQ8|ensemblfungi:YLR262C intact:EBI-15080|uniprotkb:Q03915|uniprotkb:D6VSC0|ensemblfungi:YDR137W psi-mi:ypt6_yeast(display_long)|uniprotkb:L8479.11(orf name)|uniprotkb:YLR262C(locus name)|uniprotkb:YPT6(gene name)|psi-mi:YPT6(display_short) psi-mi:rgp1_yeast(display_long)|uniprotkb:RGP1(gene name)|psi-mi:RGP1(display_short)|uniprotkb:Reduced growth phenotype protein 1(gene name synonym)|uniprotkb:YD9302.13(orf name)|uniprotkb:YDR137W(locus name) psi-mi:"MI:0096"(pull down) Siniossoglou et al. (2000) pubmed:10990452|imex:IM-18948 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2256670|imex:IM-18948-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013363.1|sgd:S000004252|dip:DIP-5577N|mint:Q99260|ensemblfungi:YLR262C(gene)|ensemblfungi:YLR262C_mRNA(transcript)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-SCE-6798695|reactome:R-SCE-6811440|reactome:R-SCE-8873719|reactome:R-SCE-8876198 refseq:NP_010421.1|sgd:S000002544|ensemblfungi:YDR137W(gene)|ensemblfungi:YDR137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0034066"(Ric1-Rgp1 guanyl-nucleotide exchange factor complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0051301"(cell division)|interpro:IPR014848(Rgp1)|reactome:R-SCE-6811440|reactome:R-SCE-8876198|dip:DIP-6486N|mint:P16664 - crc64:A8E6211FF24FAE0B crc64:4A3B311ED90ED14A figure legend:Figure 3|antagonist:GTP|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/02/17 2014/10/16 rogid:J/SeVhLd4mnvD5QEdkpsXWUH1rU559292 rogid:dO3vxD0q0ky4m2en1jsrqIkjaUs559292 intact-crc:F1C148CC656D4A50|rigid:UucHdgn94UrlagycZGxHbGOBa7Q false protein a tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P40395 uniprotkb:Q99260 intact:EBI-15183|uniprotkb:D6VY42|ensemblfungi:YLR039C intact:EBI-29503|uniprotkb:D6VYQ8|ensemblfungi:YLR262C psi-mi:ric1_yeast(display_long)|uniprotkb:RIC1(gene name)|psi-mi:RIC1(display_short)|uniprotkb:Ribosome control protein 1(gene name synonym)|uniprotkb:YLR039C(locus name)|uniprotkb:Protein RIC1(gene name synonym) psi-mi:ypt6_yeast(display_long)|uniprotkb:L8479.11(orf name)|uniprotkb:YLR262C(locus name)|uniprotkb:YPT6(gene name)|psi-mi:YPT6(display_short) psi-mi:"MI:0096"(pull down) Siniossoglou et al. (2000) pubmed:10990452|imex:IM-18948 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2266803|imex:IM-18948-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013140.1|sgd:S000004029|ensemblfungi:YLR039C(gene)|ensemblfungi:YLR039C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0034066"(Ric1-Rgp1 guanyl-nucleotide exchange factor complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR009771(Protein of unknown function DUF1339)|interpro:IPR040096|reactome:R-SCE-6811440|reactome:R-SCE-8876198|dip:DIP-2564N|mint:P40395 refseq:NP_013363.1|sgd:S000004252|dip:DIP-5577N|mint:Q99260|ensemblfungi:YLR262C(gene)|ensemblfungi:YLR262C_mRNA(transcript)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-SCE-6798695|reactome:R-SCE-6811440|reactome:R-SCE-8873719|reactome:R-SCE-8876198 - crc64:2368616B67AEAD31 crc64:A8E6211FF24FAE0B figure legend:Figure 3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/02/17 2014/10/16 rogid:m6o0B5KQhR3rrpM28RYIrAvej1k559292 rogid:J/SeVhLd4mnvD5QEdkpsXWUH1rU559292 intact-crc:F28E25CB6AE2E1A1|rigid:9ygExylnTbAqSmQu0ipoOszN7TI false green fluorescent protein tag:?-? protein a tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)