#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O46469 uniprotkb:P04695 intact:EBI-6949890|intact:UNK-6013739 intact:EBI-7052221|ensembl:ENSBTAP00000023990|intact:UNK-6021598 psi-mi:rgs9_bovin(display_long)|uniprotkb:RGS9(gene name)|psi-mi:RGS9(display_short) psi-mi:gnat1_bovin(display_long)|uniprotkb:GNAT1(gene name)|psi-mi:GNAT1(display_short)|uniprotkb:Transducin alpha-1 chain(gene name synonym) psi-mi:"MI:0096"(pull down) Skiba et al. (2000) pubmed:10973941|mint:MINT-6825840|doi:10.1074/jbc.C000413200 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7381613|mint:MINT-6825846 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0097381"(photoreceptor disc membrane)|rcsb pdb:1FQI|rcsb pdb:1FQJ|rcsb pdb:1FQK|interpro:IPR040759|interpro:IPR015898(G-protein, gamma-like subunit)|refseq:NP_776595.1|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|mint:O46469|interpro:IPR036284|interpro:IPR036305|interpro:IPR036388|interpro:IPR036390|mint:MINT-6825852(identity)|uniprotkb:O46469(O46469) ensembl:ENSBTAG00000018020(gene)|ensembl:ENSBTAT00000023990(transcript)|go:"GO:0000035"(acyl binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001973"(G protein-coupled adenosine receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007602"(phototransduction)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009416"(response to light stimulus)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0050917"(sensory perception of umami taste)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0097381"(photoreceptor disc membrane)|go:"GO:0097648"(G protein-coupled receptor complex)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:3V00|rcsb pdb:4BEY|mint:P04695|rcsb pdb:4J4Q|rcsb pdb:6OY9|rcsb pdb:1AQG|rcsb pdb:6OYA|rcsb pdb:7JSN|reactome:R-BTA-2514859|reactome:R-BTA-418594|rcsb pdb:1FQJ|rcsb pdb:1FQK|rcsb pdb:1GOT|rcsb pdb:1LVZ|rcsb pdb:1TAD|rcsb pdb:1TAG|rcsb pdb:1TND|rcsb pdb:2X72|rcsb pdb:3DQB|rcsb pdb:3PQR|refseq:XP_010815966.1|refseq:NP_851365.1|dip:DIP-29226N|mint:MINT-6825847(identity)|uniprotkb:P04695(P04695) - function:"Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(t)-alpha. Involved in phototransduction; key element in the recovery phase of visual transduction"|comment:mint function:"Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase"|comment:mint figure legend:F4|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/01/23 2014/10/16 rogid:g1l1F/XLW0//kbC4zdxvPu4C7GI9913 rogid:sQakZVwi5BGM6vu3X/xrS6R5QAk9913 intact-crc:76E8A809A78CC0F8|rigid:PXKigwo4s/EQe/Rn6uc839TlqA0 false - his tag:?-?(MINT-6825850) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant)