#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O46469 uniprotkb:A5PJS1 intact:EBI-6949890|intact:UNK-6013739 intact:EBI-6949917|uniprotkb:F1MUX3|intact:MINT-6824860 psi-mi:rgs9_bovin(display_long)|uniprotkb:RGS9(gene name)|psi-mi:RGS9(display_short) psi-mi:a5pjs1_bovin(display_long)|uniprotkb:GNB5(gene name)|psi-mi:GNB5(display_short) psi-mi:"MI:0019"(coimmunoprecipitation) Makino et al. (1999) pubmed:10051575|mint:MINT-6825398|doi:10.1073/pnas.96.5.1947 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6949937|mint:MINT-6825407 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0097381"(photoreceptor disc membrane)|rcsb pdb:1FQI|rcsb pdb:1FQJ|rcsb pdb:1FQK|interpro:IPR040759|interpro:IPR015898(G-protein, gamma-like subunit)|refseq:NP_776595.1|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|mint:O46469|interpro:IPR036284|interpro:IPR036305|interpro:IPR036388|interpro:IPR036390|mint:MINT-6825408(identity)|uniprotkb:O46469(O46469) go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|interpro:IPR001632(G-protein, beta subunit)|refseq:NP_001092540.1|interpro:IPR020472|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR015943(WD40/YVTN repeat-like)|mint:A5PJS1|interpro:IPR036322|mint:MINT-6825411(identity)|uniprotkb:A5PJS1(A5PJS1) - function:"Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(t)-alpha. Involved in phototransduction; key element in the recovery phase of visual transduction"|comment:mint comment:mint figure legend:F3A|comment:mint taxid:9913(bovine-rod outer seg)|taxid:9913(Bos taurus) - 2009/01/23 2014/10/16 rogid:g1l1F/XLW0//kbC4zdxvPu4C7GI9913 rogid:lbu9z//TG8HupDFF30yHyH1kIKA9913 intact-crc:3F4145D4C1163087|rigid:KRxkvVz0g41Aq8tFyw61qw0OH6g false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A5PJS1 uniprotkb:O46469 intact:EBI-6949917|uniprotkb:F1MUX3|intact:MINT-6824860 intact:EBI-6949890|intact:UNK-6013739 psi-mi:a5pjs1_bovin(display_long)|uniprotkb:GNB5(gene name)|psi-mi:GNB5(display_short) psi-mi:rgs9_bovin(display_long)|uniprotkb:RGS9(gene name)|psi-mi:RGS9(display_short) psi-mi:"MI:0019"(coimmunoprecipitation) Makino et al. (1999) pubmed:10051575|mint:MINT-6825398|doi:10.1073/pnas.96.5.1947 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6949965|mint:MINT-6825414 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|interpro:IPR001632(G-protein, beta subunit)|refseq:NP_001092540.1|interpro:IPR020472|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR015943(WD40/YVTN repeat-like)|mint:A5PJS1|interpro:IPR036322|mint:MINT-6825415(identity)|uniprotkb:A5PJS1(A5PJS1) go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0097381"(photoreceptor disc membrane)|rcsb pdb:1FQI|rcsb pdb:1FQJ|rcsb pdb:1FQK|interpro:IPR040759|interpro:IPR015898(G-protein, gamma-like subunit)|refseq:NP_776595.1|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|mint:O46469|interpro:IPR036284|interpro:IPR036305|interpro:IPR036388|interpro:IPR036390|mint:MINT-6825418(identity)|uniprotkb:O46469(O46469) - comment:mint function:"Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(t)-alpha. Involved in phototransduction; key element in the recovery phase of visual transduction"|comment:mint figure legend:F3B|comment:mint taxid:9913(bovine-rod outer seg)|taxid:9913(Bos taurus) - 2009/01/23 2014/10/16 rogid:lbu9z//TG8HupDFF30yHyH1kIKA9913 rogid:g1l1F/XLW0//kbC4zdxvPu4C7GI9913 intact-crc:035E02F5F4B651D5|rigid:KRxkvVz0g41Aq8tFyw61qw0OH6g false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O46469 uniprotkb:A5PJS1 intact:EBI-6949890|intact:UNK-6013739 intact:EBI-6949917|uniprotkb:F1MUX3|intact:MINT-6824860 psi-mi:rgs9_bovin(display_long)|uniprotkb:RGS9(gene name)|psi-mi:RGS9(display_short) psi-mi:a5pjs1_bovin(display_long)|uniprotkb:GNB5(gene name)|psi-mi:GNB5(display_short) psi-mi:"MI:0019"(coimmunoprecipitation) Makino et al. (1999) pubmed:10051575|mint:MINT-6825398|doi:10.1073/pnas.96.5.1947 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6950049|mint:MINT-6825423 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0097381"(photoreceptor disc membrane)|rcsb pdb:1FQI|rcsb pdb:1FQJ|rcsb pdb:1FQK|interpro:IPR040759|interpro:IPR015898(G-protein, gamma-like subunit)|refseq:NP_776595.1|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|mint:O46469|interpro:IPR036284|interpro:IPR036305|interpro:IPR036388|interpro:IPR036390|mint:MINT-6825427(identity)|uniprotkb:O46469(O46469) go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|interpro:IPR001632(G-protein, beta subunit)|refseq:NP_001092540.1|interpro:IPR020472|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR015943(WD40/YVTN repeat-like)|mint:A5PJS1|interpro:IPR036322|mint:MINT-6825424(identity)|uniprotkb:A5PJS1(A5PJS1) - function:"Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(t)-alpha. Involved in phototransduction; key element in the recovery phase of visual transduction"|comment:mint comment:mint figure legend:F4|comment:mint taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/01/23 2014/10/16 rogid:g1l1F/XLW0//kbC4zdxvPu4C7GI9913 rogid:lbu9z//TG8HupDFF30yHyH1kIKA9913 intact-crc:F20651FD317BA933|rigid:KRxkvVz0g41Aq8tFyw61qw0OH6g false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A5PJS1 uniprotkb:O46469 intact:EBI-6949917|uniprotkb:F1MUX3|intact:MINT-6824860 intact:EBI-6949890|intact:UNK-6013739 psi-mi:a5pjs1_bovin(display_long)|uniprotkb:GNB5(gene name)|psi-mi:GNB5(display_short) psi-mi:rgs9_bovin(display_long)|uniprotkb:RGS9(gene name)|psi-mi:RGS9(display_short) psi-mi:"MI:0226"(ion exchange chromatography) Makino et al. (1999) pubmed:10051575|mint:MINT-6825398|doi:10.1073/pnas.96.5.1947 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-6950069|mint:MINT-6825432 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|interpro:IPR001632(G-protein, beta subunit)|refseq:NP_001092540.1|interpro:IPR020472|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR015943(WD40/YVTN repeat-like)|mint:A5PJS1|interpro:IPR036322|mint:MINT-6825436(identity)|uniprotkb:A5PJS1(A5PJS1) go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0097381"(photoreceptor disc membrane)|rcsb pdb:1FQI|rcsb pdb:1FQJ|rcsb pdb:1FQK|interpro:IPR040759|interpro:IPR015898(G-protein, gamma-like subunit)|refseq:NP_776595.1|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|mint:O46469|interpro:IPR036284|interpro:IPR036305|interpro:IPR036388|interpro:IPR036390|mint:MINT-6825433(identity)|uniprotkb:O46469(O46469) - comment:mint function:"Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(t)-alpha. Involved in phototransduction; key element in the recovery phase of visual transduction"|comment:mint figure legend:F2|comment:mint taxid:9913(bovine-rod outer seg)|taxid:9913(Bos taurus) - 2009/01/23 2014/10/16 rogid:lbu9z//TG8HupDFF30yHyH1kIKA9913 rogid:g1l1F/XLW0//kbC4zdxvPu4C7GI9913 intact-crc:A80CF4C9FF51BC05|rigid:KRxkvVz0g41Aq8tFyw61qw0OH6g false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A5PJS1 uniprotkb:O46469 intact:EBI-6949917|uniprotkb:F1MUX3|intact:MINT-6824860 intact:EBI-6949890|intact:UNK-6013739 psi-mi:a5pjs1_bovin(display_long)|uniprotkb:GNB5(gene name)|psi-mi:GNB5(display_short) psi-mi:rgs9_bovin(display_long)|uniprotkb:RGS9(gene name)|psi-mi:RGS9(display_short) psi-mi:"MI:0071"(molecular sieving) Makino et al. (1999) pubmed:10051575|mint:MINT-6825398|doi:10.1073/pnas.96.5.1947 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-6950105|mint:MINT-6825441 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|interpro:IPR001632(G-protein, beta subunit)|refseq:NP_001092540.1|interpro:IPR020472|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR015943(WD40/YVTN repeat-like)|mint:A5PJS1|interpro:IPR036322|mint:MINT-6825445(identity)|uniprotkb:A5PJS1(A5PJS1) go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0097381"(photoreceptor disc membrane)|rcsb pdb:1FQI|rcsb pdb:1FQJ|rcsb pdb:1FQK|interpro:IPR040759|interpro:IPR015898(G-protein, gamma-like subunit)|refseq:NP_776595.1|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|mint:O46469|interpro:IPR036284|interpro:IPR036305|interpro:IPR036388|interpro:IPR036390|mint:MINT-6825442(identity)|uniprotkb:O46469(O46469) - comment:mint function:"Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(t)-alpha. Involved in phototransduction; key element in the recovery phase of visual transduction"|comment:mint figure legend:F1E|comment:mint taxid:9913(bovine-rod outer seg)|taxid:9913(Bos taurus) - 2009/01/23 2014/10/16 rogid:lbu9z//TG8HupDFF30yHyH1kIKA9913 rogid:g1l1F/XLW0//kbC4zdxvPu4C7GI9913 intact-crc:A0CE10BD86F10423|rigid:KRxkvVz0g41Aq8tFyw61qw0OH6g false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)