#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:G5EDT1	uniprotkb:P90916	intact:EBI-321470|ensemblmetazoa:C32F10.2.1	intact:EBI-324314|uniprotkb:A2JDY3|uniprotkb:O62411|ensemblmetazoa:K07A1.12.1	psi-mi:lin35_caeel(display_long)|uniprotkb:lin-35(gene name)|psi-mi:lin-35(display_short)|uniprotkb:Abnormal cell lineage protein 35(gene name synonym)|uniprotkb:Synthetic multivulva protein lin-35(gene name synonym)|uniprotkb:C32F10.2(orf name)	psi-mi:lin53_caeel(display_long)|uniprotkb:lin-53(gene name)|psi-mi:lin-53(display_short)|uniprotkb:rba-2(gene name synonym)|uniprotkb:K07A1.12(orf name)|uniprotkb:Abnormal cell lineage protein 53(gene name synonym)|uniprotkb:Synthetic multivulva protein p48(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lu et al. (1998)	pubmed:9875852|imex:IM-19785	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1571668|imex:IM-19785-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR028309|wormbase:C32F10.2|uniprotkb:O01682(uniprot-removed-ac)|ensemblmetazoa:C32F10.2.1(transcript)|ensemblmetazoa:WBGene00003020(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030154"(cell differentiation)|go:"GO:0032876"(negative regulation of DNA endoreduplication)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090727"(positive regulation of brood size)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1902807"(negative regulation of cell cycle G1/S phase transition)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR024599|refseq:NP_491686.1|reactome:R-CEL-69231|reactome:R-CEL-1538133|interpro:IPR036915|reactome:R-CEL-2173796	refseq:NP_492552.1|wormbase:K07A1.12|reactome:R-CEL-2559580|reactome:R-CEL-3214858|ensemblmetazoa:K07A1.12.1(transcript)|ensemblmetazoa:WBGene00003036(gene)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001708"(cell fate specification)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0040035"(hermaphrodite genitalia development)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0070176"(DRM complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|reactome:R-CEL-3214847|dip:DIP-24440N|reactome:R-CEL-8951664|reactome:R-CEL-8943724|reactome:R-CEL-1538133|reactome:R-CEL-212300|reactome:R-CEL-3214815|reactome:R-CEL-8953750	-	-	-	figure legend:Fig 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/07	2014/10/16	rogid:h0w54dEF5tM3DJJWeIcGp0BoWNk6239	rogid:v5/7m30zbtMyaxt8xomuotdJqcA6239	intact-crc:F15344EE27B00099|rigid:kQR+r+BflIBpCHk9OqCGXWrFLtg	false	35s radiolabel:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O17695	uniprotkb:G5EDT1	intact:EBI-318045|ensemblmetazoa:C53A5.3.1	intact:EBI-321470|ensemblmetazoa:C32F10.2.1	psi-mi:hda1_caeel(display_long)|uniprotkb:hda-1(gene name)|psi-mi:hda-1(display_short)|uniprotkb:C53A5.3(orf name)	psi-mi:lin35_caeel(display_long)|uniprotkb:lin-35(gene name)|psi-mi:lin-35(display_short)|uniprotkb:Abnormal cell lineage protein 35(gene name synonym)|uniprotkb:Synthetic multivulva protein lin-35(gene name synonym)|uniprotkb:C32F10.2(orf name)	psi-mi:"MI:0096"(pull down)	Lu et al. (1998)	pubmed:9875852|imex:IM-19785	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1571678|imex:IM-19785-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_506599.1|wormbase:C53A5.3|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:1903854"(negative regulation of stress response to copper ion)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|ensemblmetazoa:C53A5.3.1(transcript)|ensemblmetazoa:WBGene00001834(gene)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0042001"(hermaphrodite somatic sex determination)|go:"GO:0043073"(germ cell nucleus)|dip:DIP-26427N	interpro:IPR028309|wormbase:C32F10.2|uniprotkb:O01682(uniprot-removed-ac)|ensemblmetazoa:C32F10.2.1(transcript)|ensemblmetazoa:WBGene00003020(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030154"(cell differentiation)|go:"GO:0032876"(negative regulation of DNA endoreduplication)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090727"(positive regulation of brood size)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1902807"(negative regulation of cell cycle G1/S phase transition)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR024599|refseq:NP_491686.1|reactome:R-CEL-69231|reactome:R-CEL-1538133|interpro:IPR036915|reactome:R-CEL-2173796	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/07	2014/10/16	rogid:muul0dZ9oQUpxzy9aG7qV1lNlrI6239	rogid:h0w54dEF5tM3DJJWeIcGp0BoWNk6239	intact-crc:04EC3B32E96BF5C3|rigid:sMoN1frdxEbYSXOKAMjM1erZ/s8	false	glutathione s tranferase tag:n-n	35s radiolabel:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O17695	uniprotkb:P90916	intact:EBI-318045|ensemblmetazoa:C53A5.3.1	intact:EBI-324314|uniprotkb:A2JDY3|uniprotkb:O62411|ensemblmetazoa:K07A1.12.1	psi-mi:hda1_caeel(display_long)|uniprotkb:hda-1(gene name)|psi-mi:hda-1(display_short)|uniprotkb:C53A5.3(orf name)	psi-mi:lin53_caeel(display_long)|uniprotkb:lin-53(gene name)|psi-mi:lin-53(display_short)|uniprotkb:rba-2(gene name synonym)|uniprotkb:K07A1.12(orf name)|uniprotkb:Abnormal cell lineage protein 53(gene name synonym)|uniprotkb:Synthetic multivulva protein p48(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lu et al. (1998)	pubmed:9875852|imex:IM-19785	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1571685|imex:IM-19785-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_506599.1|wormbase:C53A5.3|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:1903854"(negative regulation of stress response to copper ion)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|ensemblmetazoa:C53A5.3.1(transcript)|ensemblmetazoa:WBGene00001834(gene)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0042001"(hermaphrodite somatic sex determination)|go:"GO:0043073"(germ cell nucleus)|dip:DIP-26427N	refseq:NP_492552.1|wormbase:K07A1.12|reactome:R-CEL-2559580|reactome:R-CEL-3214858|ensemblmetazoa:K07A1.12.1(transcript)|ensemblmetazoa:WBGene00003036(gene)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001708"(cell fate specification)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0040035"(hermaphrodite genitalia development)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0070176"(DRM complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|reactome:R-CEL-3214847|dip:DIP-24440N|reactome:R-CEL-8951664|reactome:R-CEL-8943724|reactome:R-CEL-1538133|reactome:R-CEL-212300|reactome:R-CEL-3214815|reactome:R-CEL-8953750	-	-	-	figure legend:Fig 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/07	2014/10/16	rogid:muul0dZ9oQUpxzy9aG7qV1lNlrI6239	rogid:v5/7m30zbtMyaxt8xomuotdJqcA6239	intact-crc:4EFBBBC800543E01|rigid:Kndjh+1yEU6qNGJQzhIb4VO3fKI	false	35s radiolabel:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)