#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P31725	uniprotkb:P27005	intact:EBI-2105496|ensembl:ENSMUSP00000070842|ensembl:ENSMUSP00000112843	intact:EBI-2105477|uniprotkb:P31724|ensembl:ENSMUSP00000064385	psi-mi:s10a9_mouse(display_long)|uniprotkb:S100a9(gene name)|psi-mi:S100a9(display_short)|uniprotkb:Cagb(gene name synonym)|uniprotkb:Mrp14(gene name synonym)|uniprotkb:S100 calcium-binding protein A9(gene name synonym)|uniprotkb:Calgranulin-B(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 14(gene name synonym)|uniprotkb:Leukocyte L1 complex heavy chain(gene name synonym)	psi-mi:s10a8_mouse(display_long)|uniprotkb:S100a8(gene name)|psi-mi:S100a8(display_short)|uniprotkb:Caga(gene name synonym)|uniprotkb:Mrp8(gene name synonym)|uniprotkb:S100 calcium-binding protein A8(gene name synonym)|uniprotkb:Calgranulin-A(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 8(gene name synonym)|uniprotkb:Leukocyte L1 complex light chain(gene name synonym)|uniprotkb:Chemotactic cytokine CP-10(gene name synonym)|uniprotkb:Pro-inflammatory S100 cytokine(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Propper et al. (1999)	pubmed:9867828|imex:IM-20167	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2105515|imex:IM-20167-1	author score:109 units	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033140.1|refseq:NP_001268781.1|ensembl:ENSMUSG00000056071(gene)|ensembl:ENSMUST00000069960(transcript)|ensembl:ENSMUST00000117167(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002793"(positive regulation of peptide secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006417"(regulation of translation)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030054"(cell junction)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0035821"(modulation of process of another organism)|go:"GO:0045087"(innate immune response)|go:"GO:0045113"(regulation of integrin biosynthetic process)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|mint:P31725|rcsb pdb:6ZDY|rcsb pdb:6ZFE|reactome:R-MMU-5668599|reactome:R-MMU-5686938|reactome:R-MMU-6798695|reactome:R-MMU-6799990	refseq:NP_038678.1|ensembl:ENSMUSG00000056054(gene)|ensembl:ENSMUST00000069927(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002793"(positive regulation of peptide secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028474|mint:P27005|reactome:R-MMU-5668599|reactome:R-MMU-5686938|reactome:R-MMU-6798695|reactome:R-MMU-6799990	-	-	-	figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/11/10	2014/10/16	rogid:nNLtk7C4uP/vZyE4ZApBBbIaHZo10090	rogid:Kqqm/88o22Ay73zHeHv+ysdrxoI10090	intact-crc:32845E8BF76845F6|rigid:j4G66PKL/Pf2i7PFmgs+XyNFGCc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P27005	uniprotkb:P31725	intact:EBI-2105477|uniprotkb:P31724|ensembl:ENSMUSP00000064385	intact:EBI-2105496|ensembl:ENSMUSP00000070842|ensembl:ENSMUSP00000112843	psi-mi:s10a8_mouse(display_long)|uniprotkb:S100a8(gene name)|psi-mi:S100a8(display_short)|uniprotkb:Caga(gene name synonym)|uniprotkb:Mrp8(gene name synonym)|uniprotkb:S100 calcium-binding protein A8(gene name synonym)|uniprotkb:Calgranulin-A(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 8(gene name synonym)|uniprotkb:Leukocyte L1 complex light chain(gene name synonym)|uniprotkb:Chemotactic cytokine CP-10(gene name synonym)|uniprotkb:Pro-inflammatory S100 cytokine(gene name synonym)	psi-mi:s10a9_mouse(display_long)|uniprotkb:S100a9(gene name)|psi-mi:S100a9(display_short)|uniprotkb:Cagb(gene name synonym)|uniprotkb:Mrp14(gene name synonym)|uniprotkb:S100 calcium-binding protein A9(gene name synonym)|uniprotkb:Calgranulin-B(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 14(gene name synonym)|uniprotkb:Leukocyte L1 complex heavy chain(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Propper et al. (1999)	pubmed:9867828|imex:IM-20167	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2105520|imex:IM-20167-2	author score:92 units	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_038678.1|ensembl:ENSMUSG00000056054(gene)|ensembl:ENSMUST00000069927(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002793"(positive regulation of peptide secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028474|mint:P27005|reactome:R-MMU-5668599|reactome:R-MMU-5686938|reactome:R-MMU-6798695|reactome:R-MMU-6799990	refseq:NP_033140.1|refseq:NP_001268781.1|ensembl:ENSMUSG00000056071(gene)|ensembl:ENSMUST00000069960(transcript)|ensembl:ENSMUST00000117167(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002793"(positive regulation of peptide secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006417"(regulation of translation)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030054"(cell junction)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0035821"(modulation of process of another organism)|go:"GO:0045087"(innate immune response)|go:"GO:0045113"(regulation of integrin biosynthetic process)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|mint:P31725|rcsb pdb:6ZDY|rcsb pdb:6ZFE|reactome:R-MMU-5668599|reactome:R-MMU-5686938|reactome:R-MMU-6798695|reactome:R-MMU-6799990	-	-	-	figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/11/10	2014/10/16	rogid:Kqqm/88o22Ay73zHeHv+ysdrxoI10090	rogid:nNLtk7C4uP/vZyE4ZApBBbIaHZo10090	intact-crc:D4E67C0E0CB076FC|rigid:j4G66PKL/Pf2i7PFmgs+XyNFGCc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P27005	uniprotkb:P27005	intact:EBI-2105477|uniprotkb:P31724|ensembl:ENSMUSP00000064385	intact:EBI-2105477|uniprotkb:P31724|ensembl:ENSMUSP00000064385	psi-mi:s10a8_mouse(display_long)|uniprotkb:S100a8(gene name)|psi-mi:S100a8(display_short)|uniprotkb:Caga(gene name synonym)|uniprotkb:Mrp8(gene name synonym)|uniprotkb:S100 calcium-binding protein A8(gene name synonym)|uniprotkb:Calgranulin-A(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 8(gene name synonym)|uniprotkb:Leukocyte L1 complex light chain(gene name synonym)|uniprotkb:Chemotactic cytokine CP-10(gene name synonym)|uniprotkb:Pro-inflammatory S100 cytokine(gene name synonym)	psi-mi:s10a8_mouse(display_long)|uniprotkb:S100a8(gene name)|psi-mi:S100a8(display_short)|uniprotkb:Caga(gene name synonym)|uniprotkb:Mrp8(gene name synonym)|uniprotkb:S100 calcium-binding protein A8(gene name synonym)|uniprotkb:Calgranulin-A(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 8(gene name synonym)|uniprotkb:Leukocyte L1 complex light chain(gene name synonym)|uniprotkb:Chemotactic cytokine CP-10(gene name synonym)|uniprotkb:Pro-inflammatory S100 cytokine(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Propper et al. (1999)	pubmed:9867828|imex:IM-20167	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2105541|imex:IM-20167-3	author score:32 units	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_038678.1|ensembl:ENSMUSG00000056054(gene)|ensembl:ENSMUST00000069927(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002793"(positive regulation of peptide secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028474|mint:P27005|reactome:R-MMU-5668599|reactome:R-MMU-5686938|reactome:R-MMU-6798695|reactome:R-MMU-6799990	refseq:NP_038678.1|ensembl:ENSMUSG00000056054(gene)|ensembl:ENSMUST00000069927(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002793"(positive regulation of peptide secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028474|mint:P27005|reactome:R-MMU-5668599|reactome:R-MMU-5686938|reactome:R-MMU-6798695|reactome:R-MMU-6799990	-	-	-	figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/11/10	2014/10/16	rogid:Kqqm/88o22Ay73zHeHv+ysdrxoI10090	rogid:Kqqm/88o22Ay73zHeHv+ysdrxoI10090	intact-crc:C5407DA05058F068|rigid:r7RoJVijLGtiVXIN1YiWjfYMMsA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P31725	uniprotkb:P31725	intact:EBI-2105496|ensembl:ENSMUSP00000070842|ensembl:ENSMUSP00000112843	intact:EBI-2105496|ensembl:ENSMUSP00000070842|ensembl:ENSMUSP00000112843	psi-mi:s10a9_mouse(display_long)|uniprotkb:S100a9(gene name)|psi-mi:S100a9(display_short)|uniprotkb:Cagb(gene name synonym)|uniprotkb:Mrp14(gene name synonym)|uniprotkb:S100 calcium-binding protein A9(gene name synonym)|uniprotkb:Calgranulin-B(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 14(gene name synonym)|uniprotkb:Leukocyte L1 complex heavy chain(gene name synonym)	psi-mi:s10a9_mouse(display_long)|uniprotkb:S100a9(gene name)|psi-mi:S100a9(display_short)|uniprotkb:Cagb(gene name synonym)|uniprotkb:Mrp14(gene name synonym)|uniprotkb:S100 calcium-binding protein A9(gene name synonym)|uniprotkb:Calgranulin-B(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 14(gene name synonym)|uniprotkb:Leukocyte L1 complex heavy chain(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Propper et al. (1999)	pubmed:9867828|imex:IM-20167	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2105563|imex:IM-20167-4	author score:28 units	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033140.1|refseq:NP_001268781.1|ensembl:ENSMUSG00000056071(gene)|ensembl:ENSMUST00000069960(transcript)|ensembl:ENSMUST00000117167(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002793"(positive regulation of peptide secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006417"(regulation of translation)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030054"(cell junction)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0035821"(modulation of process of another organism)|go:"GO:0045087"(innate immune response)|go:"GO:0045113"(regulation of integrin biosynthetic process)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|mint:P31725|rcsb pdb:6ZDY|rcsb pdb:6ZFE|reactome:R-MMU-5668599|reactome:R-MMU-5686938|reactome:R-MMU-6798695|reactome:R-MMU-6799990	refseq:NP_033140.1|refseq:NP_001268781.1|ensembl:ENSMUSG00000056071(gene)|ensembl:ENSMUST00000069960(transcript)|ensembl:ENSMUST00000117167(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002793"(positive regulation of peptide secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006417"(regulation of translation)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030054"(cell junction)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0035821"(modulation of process of another organism)|go:"GO:0045087"(innate immune response)|go:"GO:0045113"(regulation of integrin biosynthetic process)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|mint:P31725|rcsb pdb:6ZDY|rcsb pdb:6ZFE|reactome:R-MMU-5668599|reactome:R-MMU-5686938|reactome:R-MMU-6798695|reactome:R-MMU-6799990	-	-	-	figure legend:3, 4 Table1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/11/10	2014/10/16	rogid:nNLtk7C4uP/vZyE4ZApBBbIaHZo10090	rogid:nNLtk7C4uP/vZyE4ZApBBbIaHZo10090	intact-crc:8A55039BADC11C8C|rigid:uvxCyl1ts1QDSh16beQOXkK8hmI	false	-	necessary binding region:1-8|mutation decreasing interaction:20-20|mutation decreasing interaction:89-89|mutation decreasing interaction:95-95	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P06702	uniprotkb:P05109	intact:EBI-1055001|uniprotkb:Q6FGA1|uniprotkb:Q9NYM0|uniprotkb:Q9UCJ1|uniprotkb:D3DV36|ensembl:ENSP00000357727	intact:EBI-355281|uniprotkb:Q5SY70|uniprotkb:Q9UC92|uniprotkb:Q9UCJ0|uniprotkb:A8K5L3|uniprotkb:Q9UC84|uniprotkb:Q9UCM6|uniprotkb:D3DV37|ensembl:ENSP00000357721|ensembl:ENSP00000357722	psi-mi:s10a9_human(display_long)|uniprotkb:S100 calcium-binding protein A9(gene name synonym)|uniprotkb:Calgranulin-B(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 14(gene name synonym)|uniprotkb:Leukocyte L1 complex heavy chain(gene name synonym)|uniprotkb:Calprotectin L1H subunit(gene name synonym)|uniprotkb:S100A9(gene name)|psi-mi:S100A9(display_short)|uniprotkb:CAGB(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:MRP14(gene name synonym)	psi-mi:s10a8_human(display_long)|uniprotkb:S100A8(gene name)|psi-mi:S100A8(display_short)|uniprotkb:CAGA(gene name synonym)|uniprotkb:MRP8(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:S100 calcium-binding protein A8(gene name synonym)|uniprotkb:Calgranulin-A(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 8(gene name synonym)|uniprotkb:Cystic fibrosis antigen(gene name synonym)|uniprotkb:Leukocyte L1 complex light chain(gene name synonym)|uniprotkb:Calprotectin L1L subunit(gene name synonym)|uniprotkb:Urinary stone protein band A(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Propper et al. (1999)	pubmed:9867828|imex:IM-20167	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2105568|imex:IM-20167-5	author score:89 units	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002956.1|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5I8N|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENSG00000163220(gene)|ensembl:ENST00000368738(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0035821"(modulation of process of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045113"(regulation of integrin biosynthetic process)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|mint:P06702|rcsb pdb:1IRJ|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030054"(cell junction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|dip:DIP-1166N	refseq:NP_001306126.1|refseq:NP_001306127.1|refseq:NP_001306130.1|refseq:NP_002955.2|go:"GO:0042060"(wound healing)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045471"(response to ethanol)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028474|go:"GO:0035662"(Toll-like receptor 4 binding)|mint:P05109|rcsb pdb:1MR8|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5HLO|rcsb pdb:5HLV|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENST00000368732(transcript)|ensembl:ENST00000368733(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002526"(acute inflammatory response)|ensembl:ENSG00000143546(gene)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002793"(positive regulation of peptide secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010043"(response to zinc ion)|go:"GO:0014002"(astrocyte development)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|dip:DIP-1165N	-	-	-	figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/11/10	2014/10/16	rogid:IGnX4DSnv8xMr5pY4T7X7vYos5A9606	rogid:3Okfhj8fxclZ0Uo/Fa1Z89qC8Ec9606	intact-crc:0435C1567C40AED1|rigid:H2pFZ8vu4AWy810n+pB6sDWsnO4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P05109	uniprotkb:P06702	intact:EBI-355281|uniprotkb:Q5SY70|uniprotkb:Q9UC92|uniprotkb:Q9UCJ0|uniprotkb:A8K5L3|uniprotkb:Q9UC84|uniprotkb:Q9UCM6|uniprotkb:D3DV37|ensembl:ENSP00000357721|ensembl:ENSP00000357722	intact:EBI-1055001|uniprotkb:Q6FGA1|uniprotkb:Q9NYM0|uniprotkb:Q9UCJ1|uniprotkb:D3DV36|ensembl:ENSP00000357727	psi-mi:s10a8_human(display_long)|uniprotkb:S100A8(gene name)|psi-mi:S100A8(display_short)|uniprotkb:CAGA(gene name synonym)|uniprotkb:MRP8(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:S100 calcium-binding protein A8(gene name synonym)|uniprotkb:Calgranulin-A(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 8(gene name synonym)|uniprotkb:Cystic fibrosis antigen(gene name synonym)|uniprotkb:Leukocyte L1 complex light chain(gene name synonym)|uniprotkb:Calprotectin L1L subunit(gene name synonym)|uniprotkb:Urinary stone protein band A(gene name synonym)	psi-mi:s10a9_human(display_long)|uniprotkb:S100 calcium-binding protein A9(gene name synonym)|uniprotkb:Calgranulin-B(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 14(gene name synonym)|uniprotkb:Leukocyte L1 complex heavy chain(gene name synonym)|uniprotkb:Calprotectin L1H subunit(gene name synonym)|uniprotkb:S100A9(gene name)|psi-mi:S100A9(display_short)|uniprotkb:CAGB(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:MRP14(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Propper et al. (1999)	pubmed:9867828|imex:IM-20167	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2105572|imex:IM-20167-6	author score:84 units	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306126.1|refseq:NP_001306127.1|refseq:NP_001306130.1|refseq:NP_002955.2|go:"GO:0042060"(wound healing)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045471"(response to ethanol)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028474|go:"GO:0035662"(Toll-like receptor 4 binding)|mint:P05109|rcsb pdb:1MR8|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5HLO|rcsb pdb:5HLV|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENST00000368732(transcript)|ensembl:ENST00000368733(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002526"(acute inflammatory response)|ensembl:ENSG00000143546(gene)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002793"(positive regulation of peptide secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010043"(response to zinc ion)|go:"GO:0014002"(astrocyte development)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|dip:DIP-1165N	refseq:NP_002956.1|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5I8N|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENSG00000163220(gene)|ensembl:ENST00000368738(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0035821"(modulation of process of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045113"(regulation of integrin biosynthetic process)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|mint:P06702|rcsb pdb:1IRJ|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030054"(cell junction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|dip:DIP-1166N	-	-	-	figure legend:3, table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/11/10	2014/10/16	rogid:3Okfhj8fxclZ0Uo/Fa1Z89qC8Ec9606	rogid:IGnX4DSnv8xMr5pY4T7X7vYos5A9606	intact-crc:4ED06DE2DA284D8C|rigid:H2pFZ8vu4AWy810n+pB6sDWsnO4	false	-	necessary binding region:1-4|mutation decreasing interaction:3-3	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-2105591	uniprotkb:P27005	-	intact:EBI-2105477|uniprotkb:P31724|ensembl:ENSMUSP00000064385	psi-mi:mrp14-hummus(display_short)|psi-mi:EBI-2105591(display_long)	psi-mi:s10a8_mouse(display_long)|uniprotkb:S100a8(gene name)|psi-mi:S100a8(display_short)|uniprotkb:Caga(gene name synonym)|uniprotkb:Mrp8(gene name synonym)|uniprotkb:S100 calcium-binding protein A8(gene name synonym)|uniprotkb:Calgranulin-A(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 8(gene name synonym)|uniprotkb:Leukocyte L1 complex light chain(gene name synonym)|uniprotkb:Chemotactic cytokine CP-10(gene name synonym)|uniprotkb:Pro-inflammatory S100 cytokine(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Propper et al. (1999)	pubmed:9867828|imex:IM-20167	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2105601|imex:IM-20167-7	author score:64 units	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:P31725(multiple parent)|uniprotkb:P06702(multiple parent)	refseq:NP_038678.1|ensembl:ENSMUSG00000056054(gene)|ensembl:ENSMUST00000069927(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002793"(positive regulation of peptide secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028474|mint:P27005|reactome:R-MMU-5668599|reactome:R-MMU-5686938|reactome:R-MMU-6798695|reactome:R-MMU-6799990	-	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	figure legend:Table1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/11/10	2014/10/16	rogid:uuAS1HWHojsWLv7Dllfpb1Bdc2g9606	rogid:Kqqm/88o22Ay73zHeHv+ysdrxoI10090	intact-crc:FDA988D1C5BEA420|rigid:I6y0q2u/3lkyw4aXbilKCCuqiAY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P05109	intact:EBI-2105595	intact:EBI-355281|uniprotkb:Q5SY70|uniprotkb:Q9UC92|uniprotkb:Q9UCJ0|uniprotkb:A8K5L3|uniprotkb:Q9UC84|uniprotkb:Q9UCM6|uniprotkb:D3DV37|ensembl:ENSP00000357721|ensembl:ENSP00000357722	-	psi-mi:s10a8_human(display_long)|uniprotkb:S100A8(gene name)|psi-mi:S100A8(display_short)|uniprotkb:CAGA(gene name synonym)|uniprotkb:MRP8(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:S100 calcium-binding protein A8(gene name synonym)|uniprotkb:Calgranulin-A(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 8(gene name synonym)|uniprotkb:Cystic fibrosis antigen(gene name synonym)|uniprotkb:Leukocyte L1 complex light chain(gene name synonym)|uniprotkb:Calprotectin L1L subunit(gene name synonym)|uniprotkb:Urinary stone protein band A(gene name synonym)	psi-mi:mrp14-mushum(display_short)|psi-mi:EBI-2105595(display_long)	psi-mi:"MI:0018"(two hybrid)	Propper et al. (1999)	pubmed:9867828|imex:IM-20167	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2105606|imex:IM-20167-8	author score:52 units	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306126.1|refseq:NP_001306127.1|refseq:NP_001306130.1|refseq:NP_002955.2|go:"GO:0042060"(wound healing)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045471"(response to ethanol)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028474|go:"GO:0035662"(Toll-like receptor 4 binding)|mint:P05109|rcsb pdb:1MR8|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5HLO|rcsb pdb:5HLV|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENST00000368732(transcript)|ensembl:ENST00000368733(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002526"(acute inflammatory response)|ensembl:ENSG00000143546(gene)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002793"(positive regulation of peptide secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010043"(response to zinc ion)|go:"GO:0014002"(astrocyte development)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|dip:DIP-1165N	uniprotkb:P06702(multiple parent)|uniprotkb:P31725(multiple parent)	-	-	no-uniprot-update:An amino acid sequence which is not represented in UniProt	figure legend:Table1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/11/10	2014/10/16	rogid:3Okfhj8fxclZ0Uo/Fa1Z89qC8Ec9606	rogid:D+M6hCYPt/5N7W9/k7A16oR+hRs10090	intact-crc:5A4A25B75B81F4B8|rigid:KMEg2VKRLLrONPhJidIEuFTddsk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)