#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9Y295 uniprotkb:P17542 intact:EBI-719554|uniprotkb:Q6FGP8|uniprotkb:Q8WW69|uniprotkb:Q9UGF2|uniprotkb:B2RDS8|ensembl:ENSP00000329715 intact:EBI-1753878|uniprotkb:D3DQ24|ensembl:ENSP00000294339|ensembl:ENSP00000360951 psi-mi:drg1_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 3(gene name synonym)|uniprotkb:DRG1(gene name)|psi-mi:DRG1(display_short)|uniprotkb:NEDD3(gene name synonym)|uniprotkb:Translation factor GTPase DRG1(gene name synonym) psi-mi:tal1_human(display_long)|uniprotkb:TAL1(gene name)|psi-mi:TAL1(display_short)|uniprotkb:SCL(gene name synonym)|uniprotkb:TCL5(gene name synonym)|uniprotkb:Stem cell protein(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 5(gene name synonym)|uniprotkb:BHLHA17(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 17(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhao et al. (1998) pubmed:9824680 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1768195 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004138.1|go:"GO:0008017"(microtubule binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|interpro:IPR004095(TGS)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR006074(GTP1/OBG, conserved site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR027417|interpro:IPR031167|interpro:IPR031662|rcsb pdb:2EKI|go:"GO:0005844"(polysome)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0007275"(multicellular organism development)|ensembl:ENSG00000185721(gene)|ensembl:ENST00000331457(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol) refseq:NP_003180.1|refseq:NP_001277332.1|refseq:NP_001277333.1|refseq:NP_001277334.1|refseq:XP_005271217.1|refseq:NP_001277335.1|refseq:NP_001274276.1|refseq:XP_016857676.1|refseq:XP_016857677.1|refseq:XP_016857678.1|refseq:XP_016857679.1|refseq:XP_016857680.1|dip:DIP-40640N|ensembl:ENSG00000162367(gene)|ensembl:ENST00000294339(transcript)|ensembl:ENST00000371884(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007626"(locomotory behavior)|go:"GO:0019899"(enzyme binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045799"(positive regulation of chromatin assembly or disassembly)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060018"(astrocyte fate commitment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060217"(hemangioblast cell differentiation)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060375"(regulation of mast cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|rcsb pdb:2YPA|rcsb pdb:2YPB|reactome:R-HSA-8939236|reactome:R-HSA-9616222|go:"GO:0000785"(chromatin) - - - comment:The DRG clones were isolated from the human fetal liver and human thymus cDNA libraries.|author-identifiers:PREY gene AF078103|dataset:Cancer - Interactions investigated in the context of cancer taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/04/24 2014/10/16 rogid:gVbgvaeulEwp7MdnP+qRgZ/aawA9606 rogid:jLwUi22/Z+xOKRZsktn/yX6rRUo9606 intact-crc:BB78B867E9CD8638|rigid:3qsvZey/2QO6KksjQMDxPkaJgj0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P17542 uniprotkb:P15923 intact:EBI-1753878|uniprotkb:D3DQ24|ensembl:ENSP00000294339|ensembl:ENSP00000360951 intact:EBI-769630|uniprotkb:Q2TB40|uniprotkb:P15883|uniprotkb:Q14208|uniprotkb:Q14635|uniprotkb:Q14636|uniprotkb:Q9UPI9|uniprotkb:Q2TB39|intact:EBI-11119608|ensembl:ENSP00000262965 psi-mi:tal1_human(display_long)|uniprotkb:TAL1(gene name)|psi-mi:TAL1(display_short)|uniprotkb:SCL(gene name synonym)|uniprotkb:TCL5(gene name synonym)|uniprotkb:Stem cell protein(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 5(gene name synonym)|uniprotkb:BHLHA17(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 17(gene name synonym) psi-mi:tfe2_human(display_long)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Immunoglobulin transcription factor 1(gene name synonym)|uniprotkb:Transcription factor ITF-1(gene name synonym)|uniprotkb:Kappa-E2-binding factor(gene name synonym)|uniprotkb:TCF3(gene name)|psi-mi:TCF3(display_short)|uniprotkb:E2A(gene name synonym)|uniprotkb:ITF1(gene name synonym)|uniprotkb:BHLHB21(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 21(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhao et al. (1998) pubmed:9824680 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1768203 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003180.1|refseq:NP_001277332.1|refseq:NP_001277333.1|refseq:NP_001277334.1|refseq:XP_005271217.1|refseq:NP_001277335.1|refseq:NP_001274276.1|refseq:XP_016857676.1|refseq:XP_016857677.1|refseq:XP_016857678.1|refseq:XP_016857679.1|refseq:XP_016857680.1|dip:DIP-40640N|ensembl:ENSG00000162367(gene)|ensembl:ENST00000294339(transcript)|ensembl:ENST00000371884(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007626"(locomotory behavior)|go:"GO:0019899"(enzyme binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045799"(positive regulation of chromatin assembly or disassembly)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060018"(astrocyte fate commitment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060217"(hemangioblast cell differentiation)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060375"(regulation of mast cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|rcsb pdb:2YPA|rcsb pdb:2YPB|reactome:R-HSA-8939236|reactome:R-HSA-9616222|go:"GO:0000785"(chromatin) refseq:NP_001129611.1|refseq:NP_003191.1|refseq:XP_016882669.1|refseq:XP_016882670.1|refseq:XP_016882671.1|dip:DIP-74N|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|ensembl:ENSG00000071564(gene)|ensembl:ENST00000262965(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042803"(protein homodimerization activity)|rcsb pdb:2YPA|rcsb pdb:2YPB|rcsb pdb:3U5V|rcsb pdb:6MGN|reactome:R-HSA-525793|reactome:R-HSA-8939236|rcsb pdb:2MH0|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|rcsb pdb:1HLH - - - dataset:Cancer - Interactions investigated in the context of cancer taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/04/24 2014/10/16 rogid:jLwUi22/Z+xOKRZsktn/yX6rRUo9606 rogid:EybpTkEZM4cIWyf25UVHfaOaP3Y9606 intact-crc:10D4E1743772E36B|rigid:SN+35RpmpyWOvYOIDhBAYzNjwrI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P17542 uniprotkb:P15884 intact:EBI-1753878|uniprotkb:D3DQ24|ensembl:ENSP00000294339|ensembl:ENSP00000360951 intact:EBI-533224|uniprotkb:Q08AP3|uniprotkb:Q08AP2|uniprotkb:Q15440|uniprotkb:Q15441|uniprotkb:Q15439|uniprotkb:B4DT37|ensembl:ENSP00000348374|ensembl:ENSP00000457649|uniprotkb:G0LNT9|uniprotkb:G0LNU0|uniprotkb:G0LNU1|uniprotkb:G0LNU2|uniprotkb:G0LNU8|uniprotkb:G0LNU9|uniprotkb:G0LNV0|uniprotkb:G0LNV1|uniprotkb:B3KT62|uniprotkb:B3KUC0|uniprotkb:B4DUG3|uniprotkb:B7Z5M6|uniprotkb:G0LNU5|uniprotkb:H3BPQ1|uniprotkb:B7Z6Y1|uniprotkb:G0LNU4|uniprotkb:G0LNV2 psi-mi:tal1_human(display_long)|uniprotkb:TAL1(gene name)|psi-mi:TAL1(display_short)|uniprotkb:SCL(gene name synonym)|uniprotkb:TCL5(gene name synonym)|uniprotkb:Stem cell protein(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 5(gene name synonym)|uniprotkb:BHLHA17(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 17(gene name synonym) psi-mi:itf2_human(display_long)|uniprotkb:Immunoglobulin transcription factor 2(gene name synonym)|uniprotkb:SL3-3 enhancer factor 2(gene name synonym)|uniprotkb:ITF2(gene name synonym)|uniprotkb:SEF2(gene name synonym)|uniprotkb:TCF4(gene name)|psi-mi:TCF4(display_short)|uniprotkb:BHLHB19(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 19(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhao et al. (1998) pubmed:9824680 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1768210 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003180.1|refseq:NP_001277332.1|refseq:NP_001277333.1|refseq:NP_001277334.1|refseq:XP_005271217.1|refseq:NP_001277335.1|refseq:NP_001274276.1|refseq:XP_016857676.1|refseq:XP_016857677.1|refseq:XP_016857678.1|refseq:XP_016857679.1|refseq:XP_016857680.1|dip:DIP-40640N|ensembl:ENSG00000162367(gene)|ensembl:ENST00000294339(transcript)|ensembl:ENST00000371884(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007626"(locomotory behavior)|go:"GO:0019899"(enzyme binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045799"(positive regulation of chromatin assembly or disassembly)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060018"(astrocyte fate commitment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060217"(hemangioblast cell differentiation)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060375"(regulation of mast cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|rcsb pdb:2YPA|rcsb pdb:2YPB|reactome:R-HSA-8939236|reactome:R-HSA-9616222|go:"GO:0000785"(chromatin) refseq:NP_001230155.2|refseq:NP_001077431.1|refseq:NP_001230163.1|refseq:NP_003190.1|refseq:XP_005266796.2|ensembl:ENSG00000196628(gene)|ensembl:ENST00000356073(transcript)|ensembl:ENST00000564999(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070888"(E-box binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15884|rcsb pdb:2KWF|rcsb pdb:6OD3|rcsb pdb:6OD4|rcsb pdb:6OD5|reactome:R-HSA-525793|refseq:NP_001335140.1|refseq:NP_001335141.1|refseq:NP_001335142.1|refseq:NP_001335143.1|refseq:NP_001335144.1|refseq:NP_001335145.1|refseq:NP_001335146.1|refseq:NP_001335147.1|refseq:NP_001335148.1|refseq:NP_001335149.1|refseq:NP_001293136.1|refseq:NP_001293137.1|refseq:NP_001230164.1|refseq:NP_001230165.1|refseq:NP_001230160.1|refseq:NP_001230161.1|refseq:NP_001230162.1|refseq:XP_006722599.1|refseq:XP_006722600.1|refseq:NP_001230156.1|refseq:NP_001230157.1|refseq:NP_001230159.1|refseq:XP_016881425.1|refseq:XP_016881429.1|refseq:XP_016881430.1|refseq:XP_016881435.1|refseq:XP_016881445.1|dip:DIP-163N - - - dataset:Cancer - Interactions investigated in the context of cancer taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/04/24 2014/10/16 rogid:jLwUi22/Z+xOKRZsktn/yX6rRUo9606 rogid:5ofdcOZrL/NXfVfFMVO8GMyh+ZY9606 intact-crc:5F72695CCA033E81|rigid:nfHuKGX2P31Y201UigPt2MNrfpo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P17542 uniprotkb:Q99081 intact:EBI-1753878|uniprotkb:D3DQ24|ensembl:ENSP00000294339|ensembl:ENSP00000360951 intact:EBI-722877|uniprotkb:Q86VM2|ensembl:ENSP00000267811|ensembl:ENSP00000453737|uniprotkb:Q7Z3D9|uniprotkb:Q86TC1|uniprotkb:B4E1W1 psi-mi:tal1_human(display_long)|uniprotkb:TAL1(gene name)|psi-mi:TAL1(display_short)|uniprotkb:SCL(gene name synonym)|uniprotkb:TCL5(gene name synonym)|uniprotkb:Stem cell protein(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 5(gene name synonym)|uniprotkb:BHLHA17(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 17(gene name synonym) psi-mi:htf4_human(display_long)|uniprotkb:Transcription factor HTF-4(gene name synonym)|uniprotkb:E-box-binding protein(gene name synonym)|uniprotkb:DNA-binding protein HTF4(gene name synonym)|uniprotkb:TCF12(gene name)|psi-mi:TCF12(display_short)|uniprotkb:HEB(gene name synonym)|uniprotkb:HTF4(gene name synonym)|uniprotkb:BHLHB20(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 20(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhao et al. (1998) pubmed:9824680 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1768214 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003180.1|refseq:NP_001277332.1|refseq:NP_001277333.1|refseq:NP_001277334.1|refseq:XP_005271217.1|refseq:NP_001277335.1|refseq:NP_001274276.1|refseq:XP_016857676.1|refseq:XP_016857677.1|refseq:XP_016857678.1|refseq:XP_016857679.1|refseq:XP_016857680.1|dip:DIP-40640N|ensembl:ENSG00000162367(gene)|ensembl:ENST00000294339(transcript)|ensembl:ENST00000371884(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007626"(locomotory behavior)|go:"GO:0019899"(enzyme binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045799"(positive regulation of chromatin assembly or disassembly)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060018"(astrocyte fate commitment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060217"(hemangioblast cell differentiation)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060375"(regulation of mast cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|rcsb pdb:2YPA|rcsb pdb:2YPB|reactome:R-HSA-8939236|reactome:R-HSA-9616222|go:"GO:0000785"(chromatin) refseq:NP_001309086.1|refseq:NP_003196.1|refseq:NP_996919.1|refseq:NP_996920.1|refseq:NP_996921.1|refseq:NP_996923.1|ensembl:ENSG00000140262(gene)|ensembl:ENST00000267811(transcript)|ensembl:ENST00000557843(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0030154"(cell differentiation)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070888"(E-box binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:NP_001309080.1|refseq:NP_001293149.1|refseq:NP_001309088.1|refseq:NP_001309091.1|refseq:NP_001309094.1|dip:DIP-29403N|mint:Q99081|rcsb pdb:2KNH|rcsb pdb:4JOL|reactome:R-HSA-525793|reactome:R-HSA-8939236|reactome:R-HSA-9031628 - - - dataset:Cancer - Interactions investigated in the context of cancer taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/04/24 2014/10/16 rogid:jLwUi22/Z+xOKRZsktn/yX6rRUo9606 rogid:XnBrmDaoz2JZQ66PCjfJsmaQ6209606 intact-crc:02FEA5E10FF67388|rigid:dhyCYQwZ8ZOh9Eb0CN9u3K+XMDo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y295 uniprotkb:P17542 intact:EBI-719554|uniprotkb:Q6FGP8|uniprotkb:Q8WW69|uniprotkb:Q9UGF2|uniprotkb:B2RDS8|ensembl:ENSP00000329715 intact:EBI-1753878|uniprotkb:D3DQ24|ensembl:ENSP00000294339|ensembl:ENSP00000360951 psi-mi:drg1_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 3(gene name synonym)|uniprotkb:DRG1(gene name)|psi-mi:DRG1(display_short)|uniprotkb:NEDD3(gene name synonym)|uniprotkb:Translation factor GTPase DRG1(gene name synonym) psi-mi:tal1_human(display_long)|uniprotkb:TAL1(gene name)|psi-mi:TAL1(display_short)|uniprotkb:SCL(gene name synonym)|uniprotkb:TCL5(gene name synonym)|uniprotkb:Stem cell protein(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 5(gene name synonym)|uniprotkb:BHLHA17(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 17(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhao et al. (1998) pubmed:9824680 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1768226 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004138.1|go:"GO:0008017"(microtubule binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|interpro:IPR004095(TGS)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR006074(GTP1/OBG, conserved site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR027417|interpro:IPR031167|interpro:IPR031662|rcsb pdb:2EKI|go:"GO:0005844"(polysome)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0007275"(multicellular organism development)|ensembl:ENSG00000185721(gene)|ensembl:ENST00000331457(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol) refseq:NP_003180.1|refseq:NP_001277332.1|refseq:NP_001277333.1|refseq:NP_001277334.1|refseq:XP_005271217.1|refseq:NP_001277335.1|refseq:NP_001274276.1|refseq:XP_016857676.1|refseq:XP_016857677.1|refseq:XP_016857678.1|refseq:XP_016857679.1|refseq:XP_016857680.1|dip:DIP-40640N|ensembl:ENSG00000162367(gene)|ensembl:ENST00000294339(transcript)|ensembl:ENST00000371884(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007626"(locomotory behavior)|go:"GO:0019899"(enzyme binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045799"(positive regulation of chromatin assembly or disassembly)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060018"(astrocyte fate commitment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060217"(hemangioblast cell differentiation)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060375"(regulation of mast cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|rcsb pdb:2YPA|rcsb pdb:2YPB|reactome:R-HSA-8939236|reactome:R-HSA-9616222|go:"GO:0000785"(chromatin) - - - author-identifiers:PREY gene AF078103|figure legend:1|dataset:Cancer - Interactions investigated in the context of cancer taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/04/24 2014/10/16 rogid:gVbgvaeulEwp7MdnP+qRgZ/aawA9606 rogid:jLwUi22/Z+xOKRZsktn/yX6rRUo9606 intact-crc:7FAD7ED2029FB22F|rigid:3qsvZey/2QO6KksjQMDxPkaJgj0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17542 uniprotkb:P15884 intact:EBI-1753878|uniprotkb:D3DQ24|ensembl:ENSP00000294339|ensembl:ENSP00000360951 intact:EBI-533224|uniprotkb:Q08AP3|uniprotkb:Q08AP2|uniprotkb:Q15440|uniprotkb:Q15441|uniprotkb:Q15439|uniprotkb:B4DT37|ensembl:ENSP00000348374|ensembl:ENSP00000457649|uniprotkb:G0LNT9|uniprotkb:G0LNU0|uniprotkb:G0LNU1|uniprotkb:G0LNU2|uniprotkb:G0LNU8|uniprotkb:G0LNU9|uniprotkb:G0LNV0|uniprotkb:G0LNV1|uniprotkb:B3KT62|uniprotkb:B3KUC0|uniprotkb:B4DUG3|uniprotkb:B7Z5M6|uniprotkb:G0LNU5|uniprotkb:H3BPQ1|uniprotkb:B7Z6Y1|uniprotkb:G0LNU4|uniprotkb:G0LNV2 psi-mi:tal1_human(display_long)|uniprotkb:TAL1(gene name)|psi-mi:TAL1(display_short)|uniprotkb:SCL(gene name synonym)|uniprotkb:TCL5(gene name synonym)|uniprotkb:Stem cell protein(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 5(gene name synonym)|uniprotkb:BHLHA17(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 17(gene name synonym) psi-mi:itf2_human(display_long)|uniprotkb:Immunoglobulin transcription factor 2(gene name synonym)|uniprotkb:SL3-3 enhancer factor 2(gene name synonym)|uniprotkb:ITF2(gene name synonym)|uniprotkb:SEF2(gene name synonym)|uniprotkb:TCF4(gene name)|psi-mi:TCF4(display_short)|uniprotkb:BHLHB19(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 19(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhao et al. (1998) pubmed:9824680 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1768232 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003180.1|refseq:NP_001277332.1|refseq:NP_001277333.1|refseq:NP_001277334.1|refseq:XP_005271217.1|refseq:NP_001277335.1|refseq:NP_001274276.1|refseq:XP_016857676.1|refseq:XP_016857677.1|refseq:XP_016857678.1|refseq:XP_016857679.1|refseq:XP_016857680.1|dip:DIP-40640N|ensembl:ENSG00000162367(gene)|ensembl:ENST00000294339(transcript)|ensembl:ENST00000371884(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007626"(locomotory behavior)|go:"GO:0019899"(enzyme binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045799"(positive regulation of chromatin assembly or disassembly)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060018"(astrocyte fate commitment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060217"(hemangioblast cell differentiation)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060375"(regulation of mast cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|rcsb pdb:2YPA|rcsb pdb:2YPB|reactome:R-HSA-8939236|reactome:R-HSA-9616222|go:"GO:0000785"(chromatin) refseq:NP_001230155.2|refseq:NP_001077431.1|refseq:NP_001230163.1|refseq:NP_003190.1|refseq:XP_005266796.2|ensembl:ENSG00000196628(gene)|ensembl:ENST00000356073(transcript)|ensembl:ENST00000564999(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070888"(E-box binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15884|rcsb pdb:2KWF|rcsb pdb:6OD3|rcsb pdb:6OD4|rcsb pdb:6OD5|reactome:R-HSA-525793|refseq:NP_001335140.1|refseq:NP_001335141.1|refseq:NP_001335142.1|refseq:NP_001335143.1|refseq:NP_001335144.1|refseq:NP_001335145.1|refseq:NP_001335146.1|refseq:NP_001335147.1|refseq:NP_001335148.1|refseq:NP_001335149.1|refseq:NP_001293136.1|refseq:NP_001293137.1|refseq:NP_001230164.1|refseq:NP_001230165.1|refseq:NP_001230160.1|refseq:NP_001230161.1|refseq:NP_001230162.1|refseq:XP_006722599.1|refseq:XP_006722600.1|refseq:NP_001230156.1|refseq:NP_001230157.1|refseq:NP_001230159.1|refseq:XP_016881425.1|refseq:XP_016881429.1|refseq:XP_016881430.1|refseq:XP_016881435.1|refseq:XP_016881445.1|dip:DIP-163N - - - figure legend:1|dataset:Cancer - Interactions investigated in the context of cancer taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/04/24 2014/10/16 rogid:jLwUi22/Z+xOKRZsktn/yX6rRUo9606 rogid:5ofdcOZrL/NXfVfFMVO8GMyh+ZY9606 intact-crc:112068171FFDD754|rigid:nfHuKGX2P31Y201UigPt2MNrfpo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)