#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P36618	uniprotkb:Q10951	intact:EBI-1997321|ensemblfungi:"SPAC6F6.08c.1:pep"	intact:EBI-1997311|ensemblfungi:"SPAC222.10c.1:pep"	psi-mi:cdc16_schpo(display_long)|uniprotkb:cdc16(gene name)|psi-mi:cdc16(display_short)|uniprotkb:bub2(gene name synonym)|uniprotkb:SPAC6F6.08c(orf name)	psi-mi:byr4_schpo(display_long)|uniprotkb:byr4(gene name)|psi-mi:byr4(display_short)|uniprotkb:SPAC222.10c(orf name)	psi-mi:"MI:0018"(two hybrid)	Furge et al. (1998)	pubmed:9742395|imex:IM-19016	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1997310|imex:IM-19016-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_593901.1|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|ensemblfungi:SPAC6F6.08c(gene)|ensemblfungi:SPAC6F6.08c.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0010974"(negative regulation of division septum assembly)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1990334"(Bfa1-Bub2 complex)	refseq:NP_593149.1|interpro:IPR034586|ensemblfungi:SPAC222.10c(gene)|ensemblfungi:SPAC222.10c.1(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)	-	-	-	figure legend:Table 1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/09/24	2014/10/16	rogid:bebxXdmF8oRHn0ufo5F/MkCqC4U284812	rogid:6MNxyOiB+GEynY83GD8PcxfYFrQ284812	intact-crc:9D8EDF332B363F43|rigid:In86MePSQTdvKqJn37uTe4lXMNA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36618	uniprotkb:Q10951	intact:EBI-1997321|ensemblfungi:"SPAC6F6.08c.1:pep"	intact:EBI-1997311|ensemblfungi:"SPAC222.10c.1:pep"	psi-mi:cdc16_schpo(display_long)|uniprotkb:cdc16(gene name)|psi-mi:cdc16(display_short)|uniprotkb:bub2(gene name synonym)|uniprotkb:SPAC6F6.08c(orf name)	psi-mi:byr4_schpo(display_long)|uniprotkb:byr4(gene name)|psi-mi:byr4(display_short)|uniprotkb:SPAC222.10c(orf name)	psi-mi:"MI:0018"(two hybrid)	Furge et al. (1998)	pubmed:9742395|imex:IM-19016	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1999681|imex:IM-19016-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_593901.1|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|ensemblfungi:SPAC6F6.08c(gene)|ensemblfungi:SPAC6F6.08c.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0010974"(negative regulation of division septum assembly)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1990334"(Bfa1-Bub2 complex)	refseq:NP_593149.1|interpro:IPR034586|ensemblfungi:SPAC222.10c(gene)|ensemblfungi:SPAC222.10c.1(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)	-	-	-	figure legend:Table 1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/09/24	2014/10/16	rogid:bebxXdmF8oRHn0ufo5F/MkCqC4U284812	rogid:6MNxyOiB+GEynY83GD8PcxfYFrQ284812	intact-crc:0E3B22ECF0CDAA5C|rigid:In86MePSQTdvKqJn37uTe4lXMNA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P87027	uniprotkb:Q10951	intact:EBI-1999803|uniprotkb:O14312|ensemblfungi:"SPAC1565.06c.1:pep"	intact:EBI-1997311|ensemblfungi:"SPAC222.10c.1:pep"	psi-mi:spg1_schpo(display_long)|uniprotkb:spg1(gene name)|psi-mi:spg1(display_short)|uniprotkb:sid3(gene name synonym)|uniprotkb:GTPase spg1(gene name synonym)|uniprotkb:Sid3 protein(gene name synonym)|uniprotkb:SPAC1565.06c(orf name)	psi-mi:byr4_schpo(display_long)|uniprotkb:byr4(gene name)|psi-mi:byr4(display_short)|uniprotkb:SPAC222.10c(orf name)	psi-mi:"MI:0018"(two hybrid)	Furge et al. (1998)	pubmed:9742395|imex:IM-19016	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1999799|imex:IM-19016-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_593285.1|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR027417|interpro:IPR017231(Small GTPase, Tem1)|ensemblfungi:SPAC1565.06c(gene)|ensemblfungi:SPAC1565.06c.1(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005816"(spindle pole body)|go:"GO:0007049"(cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0031028"(septation initiation signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0140281"(positive regulation of mitotic division septum assembly)	refseq:NP_593149.1|interpro:IPR034586|ensemblfungi:SPAC222.10c(gene)|ensemblfungi:SPAC222.10c.1(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)	-	-	-	figure legend:Table 1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/09/24	2014/10/16	rogid:R0fx/UyOYyDNdZ9pgNICxB8k7Nc284812	rogid:6MNxyOiB+GEynY83GD8PcxfYFrQ284812	intact-crc:F8878ACB1C658F09|rigid:3gU+A0Ngwl0kZXGuUGG9GYaqQ74	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36618	uniprotkb:Q10951	intact:EBI-1997321|ensemblfungi:"SPAC6F6.08c.1:pep"	intact:EBI-1997311|ensemblfungi:"SPAC222.10c.1:pep"	psi-mi:cdc16_schpo(display_long)|uniprotkb:cdc16(gene name)|psi-mi:cdc16(display_short)|uniprotkb:bub2(gene name synonym)|uniprotkb:SPAC6F6.08c(orf name)	psi-mi:byr4_schpo(display_long)|uniprotkb:byr4(gene name)|psi-mi:byr4(display_short)|uniprotkb:SPAC222.10c(orf name)	psi-mi:"MI:0096"(pull down)	Furge et al. (1998)	pubmed:9742395|imex:IM-19016	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1999881|imex:IM-19016-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_593901.1|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|ensemblfungi:SPAC6F6.08c(gene)|ensemblfungi:SPAC6F6.08c.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0010974"(negative regulation of division septum assembly)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1990334"(Bfa1-Bub2 complex)	refseq:NP_593149.1|interpro:IPR034586|ensemblfungi:SPAC222.10c(gene)|ensemblfungi:SPAC222.10c.1(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)	-	-	-	figure legend:Figure 2b.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/09/24	2014/10/16	rogid:bebxXdmF8oRHn0ufo5F/MkCqC4U284812	rogid:6MNxyOiB+GEynY83GD8PcxfYFrQ284812	intact-crc:041151810EC089ED|rigid:In86MePSQTdvKqJn37uTe4lXMNA	false	glutathione s tranferase tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P87027	uniprotkb:Q10951	intact:EBI-1999803|uniprotkb:O14312|ensemblfungi:"SPAC1565.06c.1:pep"	intact:EBI-1997311|ensemblfungi:"SPAC222.10c.1:pep"	psi-mi:spg1_schpo(display_long)|uniprotkb:spg1(gene name)|psi-mi:spg1(display_short)|uniprotkb:sid3(gene name synonym)|uniprotkb:GTPase spg1(gene name synonym)|uniprotkb:Sid3 protein(gene name synonym)|uniprotkb:SPAC1565.06c(orf name)	psi-mi:byr4_schpo(display_long)|uniprotkb:byr4(gene name)|psi-mi:byr4(display_short)|uniprotkb:SPAC222.10c(orf name)	psi-mi:"MI:0096"(pull down)	Furge et al. (1998)	pubmed:9742395|imex:IM-19016	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1999895|imex:IM-19016-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_593285.1|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR027417|interpro:IPR017231(Small GTPase, Tem1)|ensemblfungi:SPAC1565.06c(gene)|ensemblfungi:SPAC1565.06c.1(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005816"(spindle pole body)|go:"GO:0007049"(cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0031028"(septation initiation signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0140281"(positive regulation of mitotic division septum assembly)	refseq:NP_593149.1|interpro:IPR034586|ensemblfungi:SPAC222.10c(gene)|ensemblfungi:SPAC222.10c.1(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)	-	-	-	figure legend:Figure 2b, 2c.|comment:As GTPases change conformation in response to the bound nucleotide, the effect of the nucleotide on Spg1 binding to Byr4 was determined. This analysis showed that Spg1 that was bound to either GDP or the slowly hydrolyzed GTP analog GMPPNP could bind both full-length Byr4 and degradation products that were mainly larger than 60 kDa, whereas nucleotide-free Spg1 bound full-length Byr4 primarily.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/09/24	2014/10/16	rogid:R0fx/UyOYyDNdZ9pgNICxB8k7Nc284812	rogid:6MNxyOiB+GEynY83GD8PcxfYFrQ284812	intact-crc:3A747AFD4D896087|rigid:3gU+A0Ngwl0kZXGuUGG9GYaqQ74	false	glutathione s tranferase tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:15996"	uniprotkb:Q10951	intact:EBI-989053|chebi:"CHEBI:42934"|chebi:"CHEBI:5234"|chebi:"CHEBI:13342"|chebi:"CHEBI:24451"	intact:EBI-1997311|ensemblfungi:"SPAC222.10c.1:pep"	psi-mi:gtp(display_short)|psi-mi:"CHEBI:15996"(display_long)|intact:5'-GTP(synonym)|intact:GTP(synonym)|intact:Guanosine 5'-triphosphate(synonym)|intact:guanosine 5'-triphosphoric acid(synonym)|intact:guanosine triphosphate(synonym)|intact:GUANOSINE-5'-TRIPHOSPHATE(synonym)|intact:H4gtp(synonym)|intact:"guanosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:byr4_schpo(display_long)|uniprotkb:byr4(gene name)|psi-mi:byr4(display_short)|uniprotkb:SPAC222.10c(orf name)	psi-mi:"MI:0096"(pull down)	Furge et al. (1998)	pubmed:9742395|imex:IM-19016	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2009587|imex:IM-19016-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_593149.1|interpro:IPR034586|ensemblfungi:SPAC222.10c(gene)|ensemblfungi:SPAC222.10c.1(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)	-	author-identifiers:"InChI=1/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1/f/h14,19-20,22,24H,11H2"	-	figure legend:Table 2.|comment:GST�Byr4-D8 interacted with Spg1.|comment:The GTP was gamma phosphorylated.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/09/24	2016/08/15	-	rogid:6MNxyOiB+GEynY83GD8PcxfYFrQ284812	intact-crc:25B8AFF00F82961A	false	-	binding-associated region:431-665|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q10951	uniprotkb:P87027	intact:EBI-1997311|ensemblfungi:"SPAC222.10c.1:pep"	intact:EBI-1999803|uniprotkb:O14312|ensemblfungi:"SPAC1565.06c.1:pep"	psi-mi:byr4_schpo(display_long)|uniprotkb:byr4(gene name)|psi-mi:byr4(display_short)|uniprotkb:SPAC222.10c(orf name)	psi-mi:spg1_schpo(display_long)|uniprotkb:spg1(gene name)|psi-mi:spg1(display_short)|uniprotkb:sid3(gene name synonym)|uniprotkb:GTPase spg1(gene name synonym)|uniprotkb:Sid3 protein(gene name synonym)|uniprotkb:SPAC1565.06c(orf name)	psi-mi:"MI:0096"(pull down)	Furge et al. (1998)	pubmed:9742395|imex:IM-19016	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2009587|imex:IM-19016-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_593149.1|interpro:IPR034586|ensemblfungi:SPAC222.10c(gene)|ensemblfungi:SPAC222.10c.1(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)	refseq:NP_593285.1|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR027417|interpro:IPR017231(Small GTPase, Tem1)|ensemblfungi:SPAC1565.06c(gene)|ensemblfungi:SPAC1565.06c.1(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005816"(spindle pole body)|go:"GO:0007049"(cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0031028"(septation initiation signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0140281"(positive regulation of mitotic division septum assembly)	-	-	-	figure legend:Table 2.|comment:GST�Byr4-D8 interacted with Spg1.|comment:The GTP was gamma phosphorylated.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/09/24	2016/08/15	rogid:6MNxyOiB+GEynY83GD8PcxfYFrQ284812	rogid:R0fx/UyOYyDNdZ9pgNICxB8k7Nc284812	intact-crc:25B8AFF00F82961A	false	binding-associated region:431-665|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P87027	uniprotkb:Q10951	intact:EBI-1999803|uniprotkb:O14312|ensemblfungi:"SPAC1565.06c.1:pep"	intact:EBI-1997311|ensemblfungi:"SPAC222.10c.1:pep"	psi-mi:spg1_schpo(display_long)|uniprotkb:spg1(gene name)|psi-mi:spg1(display_short)|uniprotkb:sid3(gene name synonym)|uniprotkb:GTPase spg1(gene name synonym)|uniprotkb:Sid3 protein(gene name synonym)|uniprotkb:SPAC1565.06c(orf name)	psi-mi:byr4_schpo(display_long)|uniprotkb:byr4(gene name)|psi-mi:byr4(display_short)|uniprotkb:SPAC222.10c(orf name)	psi-mi:"MI:0096"(pull down)	Furge et al. (1998)	pubmed:9742395|imex:IM-19016	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1999957|imex:IM-19016-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_593285.1|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR027417|interpro:IPR017231(Small GTPase, Tem1)|ensemblfungi:SPAC1565.06c(gene)|ensemblfungi:SPAC1565.06c.1(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005816"(spindle pole body)|go:"GO:0007049"(cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0031028"(septation initiation signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0140281"(positive regulation of mitotic division septum assembly)	refseq:NP_593149.1|interpro:IPR034586|ensemblfungi:SPAC222.10c(gene)|ensemblfungi:SPAC222.10c.1(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)	-	-	-	figure legend:Figure 2d.|comment:Byr4 was able to bind Spg1 in-vivo.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2008/09/24	2014/10/16	rogid:R0fx/UyOYyDNdZ9pgNICxB8k7Nc284812	rogid:6MNxyOiB+GEynY83GD8PcxfYFrQ284812	intact-crc:78C9279FDEEAEB8E|rigid:3gU+A0Ngwl0kZXGuUGG9GYaqQ74	false	ha tag:c-c|his tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P36618	uniprotkb:Q10951	intact:EBI-1997321|ensemblfungi:"SPAC6F6.08c.1:pep"	intact:EBI-1997311|ensemblfungi:"SPAC222.10c.1:pep"	psi-mi:cdc16_schpo(display_long)|uniprotkb:cdc16(gene name)|psi-mi:cdc16(display_short)|uniprotkb:bub2(gene name synonym)|uniprotkb:SPAC6F6.08c(orf name)	psi-mi:byr4_schpo(display_long)|uniprotkb:byr4(gene name)|psi-mi:byr4(display_short)|uniprotkb:SPAC222.10c(orf name)	psi-mi:"MI:0096"(pull down)	Furge et al. (1998)	pubmed:9742395|imex:IM-19016	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1999971|imex:IM-19016-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_593901.1|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|ensemblfungi:SPAC6F6.08c(gene)|ensemblfungi:SPAC6F6.08c.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0010974"(negative regulation of division septum assembly)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1990334"(Bfa1-Bub2 complex)	refseq:NP_593149.1|interpro:IPR034586|ensemblfungi:SPAC222.10c(gene)|ensemblfungi:SPAC222.10c.1(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)	-	-	-	figure legend:Figure 2e.|comment:Byr4 was able to bind Cdc16 in-vivo.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2008/09/24	2014/10/16	rogid:bebxXdmF8oRHn0ufo5F/MkCqC4U284812	rogid:6MNxyOiB+GEynY83GD8PcxfYFrQ284812	intact-crc:652E7955C7CA1311|rigid:In86MePSQTdvKqJn37uTe4lXMNA	false	myc tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:15996"	uniprotkb:Q10951	intact:EBI-989053|chebi:"CHEBI:42934"|chebi:"CHEBI:5234"|chebi:"CHEBI:13342"|chebi:"CHEBI:24451"	intact:EBI-1997311|ensemblfungi:"SPAC222.10c.1:pep"	psi-mi:gtp(display_short)|psi-mi:"CHEBI:15996"(display_long)|intact:5'-GTP(synonym)|intact:GTP(synonym)|intact:Guanosine 5'-triphosphate(synonym)|intact:guanosine 5'-triphosphoric acid(synonym)|intact:guanosine triphosphate(synonym)|intact:GUANOSINE-5'-TRIPHOSPHATE(synonym)|intact:H4gtp(synonym)|intact:"guanosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:byr4_schpo(display_long)|uniprotkb:byr4(gene name)|psi-mi:byr4(display_short)|uniprotkb:SPAC222.10c(orf name)	psi-mi:"MI:0419"(gtpase assay)	Furge et al. (1998)	pubmed:9742395|imex:IM-19016	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0883"(gtpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2000542|imex:IM-19016-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_593149.1|interpro:IPR034586|ensemblfungi:SPAC222.10c(gene)|ensemblfungi:SPAC222.10c.1(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)	-	author-identifiers:"InChI=1/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1/f/h14,19-20,22,24H,11H2"	-	figure legend:Figure 3c.|comment:The GTP was gamma phosphorylated.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/09/24	2016/08/15	-	rogid:6MNxyOiB+GEynY83GD8PcxfYFrQ284812	intact-crc:0C4D514195426791	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q10951	uniprotkb:P87027	intact:EBI-1997311|ensemblfungi:"SPAC222.10c.1:pep"	intact:EBI-1999803|uniprotkb:O14312|ensemblfungi:"SPAC1565.06c.1:pep"	psi-mi:byr4_schpo(display_long)|uniprotkb:byr4(gene name)|psi-mi:byr4(display_short)|uniprotkb:SPAC222.10c(orf name)	psi-mi:spg1_schpo(display_long)|uniprotkb:spg1(gene name)|psi-mi:spg1(display_short)|uniprotkb:sid3(gene name synonym)|uniprotkb:GTPase spg1(gene name synonym)|uniprotkb:Sid3 protein(gene name synonym)|uniprotkb:SPAC1565.06c(orf name)	psi-mi:"MI:0419"(gtpase assay)	Furge et al. (1998)	pubmed:9742395|imex:IM-19016	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0883"(gtpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2000542|imex:IM-19016-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_593149.1|interpro:IPR034586|ensemblfungi:SPAC222.10c(gene)|ensemblfungi:SPAC222.10c.1(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)	refseq:NP_593285.1|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR027417|interpro:IPR017231(Small GTPase, Tem1)|ensemblfungi:SPAC1565.06c(gene)|ensemblfungi:SPAC1565.06c.1(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005816"(spindle pole body)|go:"GO:0007049"(cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0031028"(septation initiation signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0140281"(positive regulation of mitotic division septum assembly)	-	-	-	figure legend:Figure 3c.|comment:The GTP was gamma phosphorylated.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/09/24	2016/08/15	rogid:6MNxyOiB+GEynY83GD8PcxfYFrQ284812	rogid:R0fx/UyOYyDNdZ9pgNICxB8k7Nc284812	intact-crc:0C4D514195426791	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36618	uniprotkb:P87027	intact:EBI-1997321|ensemblfungi:"SPAC6F6.08c.1:pep"	intact:EBI-1999803|uniprotkb:O14312|ensemblfungi:"SPAC1565.06c.1:pep"	psi-mi:cdc16_schpo(display_long)|uniprotkb:cdc16(gene name)|psi-mi:cdc16(display_short)|uniprotkb:bub2(gene name synonym)|uniprotkb:SPAC6F6.08c(orf name)	psi-mi:spg1_schpo(display_long)|uniprotkb:spg1(gene name)|psi-mi:spg1(display_short)|uniprotkb:sid3(gene name synonym)|uniprotkb:GTPase spg1(gene name synonym)|uniprotkb:Sid3 protein(gene name synonym)|uniprotkb:SPAC1565.06c(orf name)	psi-mi:"MI:0419"(gtpase assay)	Furge et al. (1998)	pubmed:9742395|imex:IM-19016	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0883"(gtpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2000562|imex:IM-19016-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_593901.1|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|ensemblfungi:SPAC6F6.08c(gene)|ensemblfungi:SPAC6F6.08c.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0010974"(negative regulation of division septum assembly)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1990334"(Bfa1-Bub2 complex)	refseq:NP_593285.1|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR027417|interpro:IPR017231(Small GTPase, Tem1)|ensemblfungi:SPAC1565.06c(gene)|ensemblfungi:SPAC1565.06c.1(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005816"(spindle pole body)|go:"GO:0007049"(cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0031028"(septation initiation signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0140281"(positive regulation of mitotic division septum assembly)	-	-	-	figure legend:Figure 3d.|comment:The GTP was gamma phosphorylated.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/09/24	2016/08/15	rogid:bebxXdmF8oRHn0ufo5F/MkCqC4U284812	rogid:R0fx/UyOYyDNdZ9pgNICxB8k7Nc284812	intact-crc:64554A760AD44E9E	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36618	uniprotkb:Q10951	intact:EBI-1997321|ensemblfungi:"SPAC6F6.08c.1:pep"	intact:EBI-1997311|ensemblfungi:"SPAC222.10c.1:pep"	psi-mi:cdc16_schpo(display_long)|uniprotkb:cdc16(gene name)|psi-mi:cdc16(display_short)|uniprotkb:bub2(gene name synonym)|uniprotkb:SPAC6F6.08c(orf name)	psi-mi:byr4_schpo(display_long)|uniprotkb:byr4(gene name)|psi-mi:byr4(display_short)|uniprotkb:SPAC222.10c(orf name)	psi-mi:"MI:0419"(gtpase assay)	Furge et al. (1998)	pubmed:9742395|imex:IM-19016	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0883"(gtpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2000562|imex:IM-19016-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_593901.1|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|ensemblfungi:SPAC6F6.08c(gene)|ensemblfungi:SPAC6F6.08c.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0010974"(negative regulation of division septum assembly)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1990334"(Bfa1-Bub2 complex)	refseq:NP_593149.1|interpro:IPR034586|ensemblfungi:SPAC222.10c(gene)|ensemblfungi:SPAC222.10c.1(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)	-	-	-	figure legend:Figure 3d.|comment:The GTP was gamma phosphorylated.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/09/24	2016/08/15	rogid:bebxXdmF8oRHn0ufo5F/MkCqC4U284812	rogid:6MNxyOiB+GEynY83GD8PcxfYFrQ284812	intact-crc:64554A760AD44E9E	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15996"	uniprotkb:P36618	intact:EBI-989053|chebi:"CHEBI:42934"|chebi:"CHEBI:5234"|chebi:"CHEBI:13342"|chebi:"CHEBI:24451"	intact:EBI-1997321|ensemblfungi:"SPAC6F6.08c.1:pep"	psi-mi:gtp(display_short)|psi-mi:"CHEBI:15996"(display_long)|intact:5'-GTP(synonym)|intact:GTP(synonym)|intact:Guanosine 5'-triphosphate(synonym)|intact:guanosine 5'-triphosphoric acid(synonym)|intact:guanosine triphosphate(synonym)|intact:GUANOSINE-5'-TRIPHOSPHATE(synonym)|intact:H4gtp(synonym)|intact:"guanosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:cdc16_schpo(display_long)|uniprotkb:cdc16(gene name)|psi-mi:cdc16(display_short)|uniprotkb:bub2(gene name synonym)|uniprotkb:SPAC6F6.08c(orf name)	psi-mi:"MI:0419"(gtpase assay)	Furge et al. (1998)	pubmed:9742395|imex:IM-19016	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0883"(gtpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2000562|imex:IM-19016-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_593901.1|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|ensemblfungi:SPAC6F6.08c(gene)|ensemblfungi:SPAC6F6.08c.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0010974"(negative regulation of division septum assembly)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1990334"(Bfa1-Bub2 complex)	-	author-identifiers:"InChI=1/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1/f/h14,19-20,22,24H,11H2"	-	figure legend:Figure 3d.|comment:The GTP was gamma phosphorylated.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/09/24	2016/08/15	-	rogid:bebxXdmF8oRHn0ufo5F/MkCqC4U284812	intact-crc:64554A760AD44E9E	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15996"	uniprotkb:P87027	intact:EBI-989053|chebi:"CHEBI:42934"|chebi:"CHEBI:5234"|chebi:"CHEBI:13342"|chebi:"CHEBI:24451"	intact:EBI-1999803|uniprotkb:O14312|ensemblfungi:"SPAC1565.06c.1:pep"	psi-mi:gtp(display_short)|psi-mi:"CHEBI:15996"(display_long)|intact:5'-GTP(synonym)|intact:GTP(synonym)|intact:Guanosine 5'-triphosphate(synonym)|intact:guanosine 5'-triphosphoric acid(synonym)|intact:guanosine triphosphate(synonym)|intact:GUANOSINE-5'-TRIPHOSPHATE(synonym)|intact:H4gtp(synonym)|intact:"guanosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:spg1_schpo(display_long)|uniprotkb:spg1(gene name)|psi-mi:spg1(display_short)|uniprotkb:sid3(gene name synonym)|uniprotkb:GTPase spg1(gene name synonym)|uniprotkb:Sid3 protein(gene name synonym)|uniprotkb:SPAC1565.06c(orf name)	psi-mi:"MI:0419"(gtpase assay)	Furge et al. (1998)	pubmed:9742395|imex:IM-19016	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0883"(gtpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2000625|imex:IM-19016-13	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_593285.1|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR027417|interpro:IPR017231(Small GTPase, Tem1)|ensemblfungi:SPAC1565.06c(gene)|ensemblfungi:SPAC1565.06c.1(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005816"(spindle pole body)|go:"GO:0007049"(cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0031028"(septation initiation signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0140281"(positive regulation of mitotic division septum assembly)	go:"GO:0003924"(GTPase activity)	author-identifiers:"InChI=1/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1/f/h14,19-20,22,24H,11H2"	-	figure legend:Figure 3a.|comment:GTP is gamma phosphorylated|kinetics:GTP hydrolysis rate was calculated to be 0.2 min-1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/09/24	2016/08/15	-	rogid:R0fx/UyOYyDNdZ9pgNICxB8k7Nc284812	intact-crc:E616A51F2E97CB33	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q10951	uniprotkb:P36618	intact:EBI-1997311|ensemblfungi:"SPAC222.10c.1:pep"	intact:EBI-1997321|ensemblfungi:"SPAC6F6.08c.1:pep"	psi-mi:byr4_schpo(display_long)|uniprotkb:byr4(gene name)|psi-mi:byr4(display_short)|uniprotkb:SPAC222.10c(orf name)	psi-mi:cdc16_schpo(display_long)|uniprotkb:cdc16(gene name)|psi-mi:cdc16(display_short)|uniprotkb:bub2(gene name synonym)|uniprotkb:SPAC6F6.08c(orf name)	psi-mi:"MI:0419"(gtpase assay)	Furge et al. (1998)	pubmed:9742395|imex:IM-19016	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2000639|imex:IM-19016-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_593149.1|interpro:IPR034586|ensemblfungi:SPAC222.10c(gene)|ensemblfungi:SPAC222.10c.1(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)	refseq:NP_593901.1|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|ensemblfungi:SPAC6F6.08c(gene)|ensemblfungi:SPAC6F6.08c.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0010974"(negative regulation of division septum assembly)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1990334"(Bfa1-Bub2 complex)	-	-	-	figure legend:Table 2.|comment:The combined GTP dissociation rate and hydrolysis rate for Spg1 GTPase based on the decrease in filter-bound GTPase-[g-32P]GTP was high in the presence of 100 nM Cdc16,  but even greater in the presence of both 100 nM Cdc16 and 50 nM Byr4.|comment:The GTP was gamma phosphorylated.|kinetics:"The combined GTP dissociation rate and hydrolysis rate increased from 0.2min-1 (no added protein) to >2min-1 on addition of both 100 nM Cdc16 and 50 nM Byr4"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/09/24	2016/08/15	rogid:6MNxyOiB+GEynY83GD8PcxfYFrQ284812	rogid:bebxXdmF8oRHn0ufo5F/MkCqC4U284812	intact-crc:2555B7B6D79B1F5F	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15996"	uniprotkb:Q10951	intact:EBI-989053|chebi:"CHEBI:42934"|chebi:"CHEBI:5234"|chebi:"CHEBI:13342"|chebi:"CHEBI:24451"	intact:EBI-1997311|ensemblfungi:"SPAC222.10c.1:pep"	psi-mi:gtp(display_short)|psi-mi:"CHEBI:15996"(display_long)|intact:5'-GTP(synonym)|intact:GTP(synonym)|intact:Guanosine 5'-triphosphate(synonym)|intact:guanosine 5'-triphosphoric acid(synonym)|intact:guanosine triphosphate(synonym)|intact:GUANOSINE-5'-TRIPHOSPHATE(synonym)|intact:H4gtp(synonym)|intact:"guanosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:byr4_schpo(display_long)|uniprotkb:byr4(gene name)|psi-mi:byr4(display_short)|uniprotkb:SPAC222.10c(orf name)	psi-mi:"MI:0419"(gtpase assay)	Furge et al. (1998)	pubmed:9742395|imex:IM-19016	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2000639|imex:IM-19016-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_593149.1|interpro:IPR034586|ensemblfungi:SPAC222.10c(gene)|ensemblfungi:SPAC222.10c.1(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)	-	author-identifiers:"InChI=1/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1/f/h14,19-20,22,24H,11H2"	-	figure legend:Table 2.|comment:The combined GTP dissociation rate and hydrolysis rate for Spg1 GTPase based on the decrease in filter-bound GTPase-[g-32P]GTP was high in the presence of 100 nM Cdc16,  but even greater in the presence of both 100 nM Cdc16 and 50 nM Byr4.|comment:The GTP was gamma phosphorylated.|kinetics:"The combined GTP dissociation rate and hydrolysis rate increased from 0.2min-1 (no added protein) to >2min-1 on addition of both 100 nM Cdc16 and 50 nM Byr4"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/09/24	2016/08/15	-	rogid:6MNxyOiB+GEynY83GD8PcxfYFrQ284812	intact-crc:2555B7B6D79B1F5F	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q10951	uniprotkb:P87027	intact:EBI-1997311|ensemblfungi:"SPAC222.10c.1:pep"	intact:EBI-1999803|uniprotkb:O14312|ensemblfungi:"SPAC1565.06c.1:pep"	psi-mi:byr4_schpo(display_long)|uniprotkb:byr4(gene name)|psi-mi:byr4(display_short)|uniprotkb:SPAC222.10c(orf name)	psi-mi:spg1_schpo(display_long)|uniprotkb:spg1(gene name)|psi-mi:spg1(display_short)|uniprotkb:sid3(gene name synonym)|uniprotkb:GTPase spg1(gene name synonym)|uniprotkb:Sid3 protein(gene name synonym)|uniprotkb:SPAC1565.06c(orf name)	psi-mi:"MI:0419"(gtpase assay)	Furge et al. (1998)	pubmed:9742395|imex:IM-19016	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2000639|imex:IM-19016-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_593149.1|interpro:IPR034586|ensemblfungi:SPAC222.10c(gene)|ensemblfungi:SPAC222.10c.1(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)	refseq:NP_593285.1|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR027417|interpro:IPR017231(Small GTPase, Tem1)|ensemblfungi:SPAC1565.06c(gene)|ensemblfungi:SPAC1565.06c.1(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005816"(spindle pole body)|go:"GO:0007049"(cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0031028"(septation initiation signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0140281"(positive regulation of mitotic division septum assembly)	-	-	-	figure legend:Table 2.|comment:The combined GTP dissociation rate and hydrolysis rate for Spg1 GTPase based on the decrease in filter-bound GTPase-[g-32P]GTP was high in the presence of 100 nM Cdc16,  but even greater in the presence of both 100 nM Cdc16 and 50 nM Byr4.|comment:The GTP was gamma phosphorylated.|kinetics:"The combined GTP dissociation rate and hydrolysis rate increased from 0.2min-1 (no added protein) to >2min-1 on addition of both 100 nM Cdc16 and 50 nM Byr4"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/09/24	2016/08/15	rogid:6MNxyOiB+GEynY83GD8PcxfYFrQ284812	rogid:R0fx/UyOYyDNdZ9pgNICxB8k7Nc284812	intact-crc:2555B7B6D79B1F5F	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15996"	uniprotkb:Q10951	intact:EBI-989053|chebi:"CHEBI:42934"|chebi:"CHEBI:5234"|chebi:"CHEBI:13342"|chebi:"CHEBI:24451"	intact:EBI-1997311|ensemblfungi:"SPAC222.10c.1:pep"	psi-mi:gtp(display_short)|psi-mi:"CHEBI:15996"(display_long)|intact:5'-GTP(synonym)|intact:GTP(synonym)|intact:Guanosine 5'-triphosphate(synonym)|intact:guanosine 5'-triphosphoric acid(synonym)|intact:guanosine triphosphate(synonym)|intact:GUANOSINE-5'-TRIPHOSPHATE(synonym)|intact:H4gtp(synonym)|intact:"guanosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:byr4_schpo(display_long)|uniprotkb:byr4(gene name)|psi-mi:byr4(display_short)|uniprotkb:SPAC222.10c(orf name)	psi-mi:"MI:0419"(gtpase assay)	Furge et al. (1998)	pubmed:9742395|imex:IM-19016	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0883"(gtpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2009512|imex:IM-19016-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_593149.1|interpro:IPR034586|ensemblfungi:SPAC222.10c(gene)|ensemblfungi:SPAC222.10c.1(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)	-	author-identifiers:"InChI=1/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1/f/h14,19-20,22,24H,11H2"	-	figure legend:Table 2.|comment:50 nM Byr4 seemed to have an inhibitory effect on kinetics of hydrolysis of GTPase.|comment:The GTP was gamma phosphorylated.|kinetics:"The combined GTP dissociation and hydrolysis rate decreased from 0.2min-1 (no added protein) to 0.01min-1 on addition of 50 nM byr4."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/09/24	2016/08/15	-	rogid:6MNxyOiB+GEynY83GD8PcxfYFrQ284812	intact-crc:4CB900BA4B29AEDB	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q10951	uniprotkb:P87027	intact:EBI-1997311|ensemblfungi:"SPAC222.10c.1:pep"	intact:EBI-1999803|uniprotkb:O14312|ensemblfungi:"SPAC1565.06c.1:pep"	psi-mi:byr4_schpo(display_long)|uniprotkb:byr4(gene name)|psi-mi:byr4(display_short)|uniprotkb:SPAC222.10c(orf name)	psi-mi:spg1_schpo(display_long)|uniprotkb:spg1(gene name)|psi-mi:spg1(display_short)|uniprotkb:sid3(gene name synonym)|uniprotkb:GTPase spg1(gene name synonym)|uniprotkb:Sid3 protein(gene name synonym)|uniprotkb:SPAC1565.06c(orf name)	psi-mi:"MI:0419"(gtpase assay)	Furge et al. (1998)	pubmed:9742395|imex:IM-19016	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0883"(gtpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2009512|imex:IM-19016-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_593149.1|interpro:IPR034586|ensemblfungi:SPAC222.10c(gene)|ensemblfungi:SPAC222.10c.1(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0071957"(old mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)	refseq:NP_593285.1|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR027417|interpro:IPR017231(Small GTPase, Tem1)|ensemblfungi:SPAC1565.06c(gene)|ensemblfungi:SPAC1565.06c.1(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005816"(spindle pole body)|go:"GO:0007049"(cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0031028"(septation initiation signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0140281"(positive regulation of mitotic division septum assembly)	-	-	-	figure legend:Table 2.|comment:50 nM Byr4 seemed to have an inhibitory effect on kinetics of hydrolysis of GTPase.|comment:The GTP was gamma phosphorylated.|kinetics:"The combined GTP dissociation and hydrolysis rate decreased from 0.2min-1 (no added protein) to 0.01min-1 on addition of 50 nM byr4."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/09/24	2016/08/15	rogid:6MNxyOiB+GEynY83GD8PcxfYFrQ284812	rogid:R0fx/UyOYyDNdZ9pgNICxB8k7Nc284812	intact-crc:4CB900BA4B29AEDB	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)