#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P43254 uniprotkb:O24646 intact:EBI-301649|uniprotkb:O23974|uniprotkb:O23975|uniprotkb:O48770|ensemblplants:AT2G32950.1|uniprotkb:Q1JPL6 intact:EBI-301660|ensemblplants:AT5G11260.1 psi-mi:cop1_arath(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:Constitutive photomorphogenesis protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase COP1(gene name synonym)|uniprotkb:T21L14.11(orf name)|uniprotkb:At2g32950(locus name) psi-mi:hy5_arath(display_long)|uniprotkb:HY5(gene name)|psi-mi:HY5(display_short)|uniprotkb:BZIP56(gene name synonym)|uniprotkb:At5g11260(locus name)|uniprotkb:F2I11_150(orf name)|uniprotkb:Protein LONG HYPOCOTYL 5(gene name synonym)|uniprotkb:bZIP transcription factor 56(gene name synonym) psi-mi:"MI:0018"(two hybrid) Ang et al. (1998) pubmed:9659918|imex:IM-20012|mint:MINT-6547981 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1646215|imex:IM-20012-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P43254|ensemblplants:AT2G32950(gene)|ensemblplants:AT2G32950.1(transcript)|go:"GO:0000152"(nuclear ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0009585"(red, far-red light phototransduction)|go:"GO:0009640"(photomorphogenesis)|go:"GO:0009641"(shade avoidance)|go:"GO:0009647"(skotomorphogenesis)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0010119"(regulation of stomatal movement)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0046283"(anthocyanin-containing compound metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048573"(photoperiodism, flowering)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017907|interpro:IPR019775|interpro:IPR036322|interpro:IPR042755|rcsb pdb:5IGO|rcsb pdb:5KWN|rcsb pdb:6QTO|rcsb pdb:6QTQ|rcsb pdb:6QTR|rcsb pdb:6QTS|rcsb pdb:6QTT|rcsb pdb:6QTU|rcsb pdb:6QTV|rcsb pdb:6QTW|rcsb pdb:6QTX|refseq:NP_180854.1|dip:DIP-32850N ensemblplants:AT5G11260(gene)|ensemblplants:AT5G11260.1(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0009585"(red, far-red light phototransduction)|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009738"(abscisic acid-activated signaling pathway)|go:"GO:0009740"(gibberellic acid mediated signaling pathway)|go:"GO:0009787"(regulation of abscisic acid-activated signaling pathway)|go:"GO:0009958"(positive gravitropism)|go:"GO:0010017"(red or far-red light signaling pathway)|go:"GO:0010099"(regulation of photomorphogenesis)|go:"GO:0010114"(response to red light)|go:"GO:0010218"(response to far red light)|go:"GO:0010224"(response to UV-B)|go:"GO:0031539"(positive regulation of anthocyanin metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0080167"(response to karrikin)|refseq:NP_568246.1|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:2OQQ|interpro:IPR044280|rcsb pdb:5KWN|rcsb pdb:6QTO|rcsb pdb:6QTR - - - figure legend:Figure 1B and Figure 1C|comment:"the authors conclude \"The N-terminal 77 amino acids of HY5 are essential and sufficient for COP1 interaction in yeast\" and the \"overall structure of COP1 is necessary for interaction with HY5\"."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/03/06 2014/10/16 rogid:73stYlIzphnYjTII2gab3+DD60E3702 rogid:mtSJUqb35GWoprnSuB3E/5FHC0k3702 intact-crc:2948E6FD0964843B|rigid:Sw4+3oTnfbmp0xJPbjtyMdvAX/8 false - necessary binding region:1-77 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43254 uniprotkb:O24646 intact:EBI-301649|uniprotkb:O23974|uniprotkb:O23975|uniprotkb:O48770|ensemblplants:AT2G32950.1|uniprotkb:Q1JPL6 intact:EBI-301660|ensemblplants:AT5G11260.1 psi-mi:cop1_arath(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:Constitutive photomorphogenesis protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase COP1(gene name synonym)|uniprotkb:T21L14.11(orf name)|uniprotkb:At2g32950(locus name) psi-mi:hy5_arath(display_long)|uniprotkb:HY5(gene name)|psi-mi:HY5(display_short)|uniprotkb:BZIP56(gene name synonym)|uniprotkb:At5g11260(locus name)|uniprotkb:F2I11_150(orf name)|uniprotkb:Protein LONG HYPOCOTYL 5(gene name synonym)|uniprotkb:bZIP transcription factor 56(gene name synonym) psi-mi:"MI:0096"(pull down) Ang et al. (1998) pubmed:9659918|imex:IM-20012|mint:MINT-6547981 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1646230|imex:IM-20012-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P43254|ensemblplants:AT2G32950(gene)|ensemblplants:AT2G32950.1(transcript)|go:"GO:0000152"(nuclear ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0009585"(red, far-red light phototransduction)|go:"GO:0009640"(photomorphogenesis)|go:"GO:0009641"(shade avoidance)|go:"GO:0009647"(skotomorphogenesis)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0010119"(regulation of stomatal movement)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0046283"(anthocyanin-containing compound metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048573"(photoperiodism, flowering)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017907|interpro:IPR019775|interpro:IPR036322|interpro:IPR042755|rcsb pdb:5IGO|rcsb pdb:5KWN|rcsb pdb:6QTO|rcsb pdb:6QTQ|rcsb pdb:6QTR|rcsb pdb:6QTS|rcsb pdb:6QTT|rcsb pdb:6QTU|rcsb pdb:6QTV|rcsb pdb:6QTW|rcsb pdb:6QTX|refseq:NP_180854.1|dip:DIP-32850N ensemblplants:AT5G11260(gene)|ensemblplants:AT5G11260.1(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0009585"(red, far-red light phototransduction)|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009738"(abscisic acid-activated signaling pathway)|go:"GO:0009740"(gibberellic acid mediated signaling pathway)|go:"GO:0009787"(regulation of abscisic acid-activated signaling pathway)|go:"GO:0009958"(positive gravitropism)|go:"GO:0010017"(red or far-red light signaling pathway)|go:"GO:0010099"(regulation of photomorphogenesis)|go:"GO:0010114"(response to red light)|go:"GO:0010218"(response to far red light)|go:"GO:0010224"(response to UV-B)|go:"GO:0031539"(positive regulation of anthocyanin metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0080167"(response to karrikin)|refseq:NP_568246.1|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:2OQQ|interpro:IPR044280|rcsb pdb:5KWN|rcsb pdb:6QTO|rcsb pdb:6QTR - - - figure legend:Figure 1A|caution:"The authors state that \"The purification and labeling of the flag-tagged COP1 protein containing a HMK kinase domain with 32P-ATP, as well as the binding assay were performed as previously described (Matsui et al., 1995) with minor modifications\". However there appears to be no reference to flag-tagged COP1 in that report."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/03/06 2014/10/16 rogid:73stYlIzphnYjTII2gab3+DD60E3702 rogid:mtSJUqb35GWoprnSuB3E/5FHC0k3702 intact-crc:AE097248FE97E18F|rigid:Sw4+3oTnfbmp0xJPbjtyMdvAX/8 false 32p radiolabel:?-?|flag tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:O24646 intact:EBI-1646366 intact:EBI-301660|ensemblplants:AT5G11260.1 - psi-mi:hy5_arath(display_long)|uniprotkb:HY5(gene name)|psi-mi:HY5(display_short)|uniprotkb:BZIP56(gene name synonym)|uniprotkb:At5g11260(locus name)|uniprotkb:F2I11_150(orf name)|uniprotkb:Protein LONG HYPOCOTYL 5(gene name synonym)|uniprotkb:bZIP transcription factor 56(gene name synonym) psi-mi:chs-sinal-dna(display_short)|psi-mi:EBI-1646366(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Ang et al. (1998) pubmed:9659918|imex:IM-20012|mint:MINT-6547981 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3728(sinal)|taxid:3728("Sinapis alba (White mustard)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1646377|imex:IM-20012-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0681"(double stranded deoxyribonucleic acid) ensemblplants:AT5G11260(gene)|ensemblplants:AT5G11260.1(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0009585"(red, far-red light phototransduction)|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009738"(abscisic acid-activated signaling pathway)|go:"GO:0009740"(gibberellic acid mediated signaling pathway)|go:"GO:0009787"(regulation of abscisic acid-activated signaling pathway)|go:"GO:0009958"(positive gravitropism)|go:"GO:0010017"(red or far-red light signaling pathway)|go:"GO:0010099"(regulation of photomorphogenesis)|go:"GO:0010114"(response to red light)|go:"GO:0010218"(response to far red light)|go:"GO:0010224"(response to UV-B)|go:"GO:0031539"(positive regulation of anthocyanin metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0080167"(response to karrikin)|refseq:NP_568246.1|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:2OQQ|interpro:IPR044280|rcsb pdb:5KWN|rcsb pdb:6QTO|rcsb pdb:6QTR pubmed:9659918(see-also) - - comment:"The authors in the relevant paper (see PMID:9659918) describe this as \"180 bp fragment of the CHS promoter that includes the Unit 1 region: 2247 to 268\". They reference the promoter as the CHS promoter region from white mustard (Sinapis alba) and reference this with PMID 7599309." figure legend:Figure 6|comment:Binding of HY5 to the DNA probe was abolished by the presence of unlabelled synthetic consensus G-box tetramer and the DNA region described by the authors as Unit1 which contains the G box like motif.|comment:The DNA probe was 32P labelled.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/03/06 2014/10/16 rogid:mtSJUqb35GWoprnSuB3E/5FHC0k3702 - intact-crc:12671172BC9B0110 false glutathione s tranferase tag:?-? - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)