#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q38846	uniprotkb:Q05609	intact:EBI-1606754|ensemblplants:AT2G40940.1	intact:EBI-1606697|ensemblplants:AT5G03730.1|ensemblplants:AT5G03730.2	psi-mi:ers1_arath(display_long)|uniprotkb:ERS1(gene name)|psi-mi:ERS1(display_short)|uniprotkb:ERS(gene name synonym)|uniprotkb:At2g40940(locus name)|uniprotkb:Protein ERS1(gene name synonym)|uniprotkb:T20B5.14(orf name)	psi-mi:ctr1_arath(display_long)|uniprotkb:Protein CONSTITUTIVE TRIPLE RESPONSE1(gene name synonym)|uniprotkb:F17C15_150(orf name)|uniprotkb:CTR1(gene name)|psi-mi:CTR1(display_short)|uniprotkb:At5g03730(locus name)	psi-mi:"MI:0018"(two hybrid)	Clark et al. (1998)	pubmed:9560288|imex:IM-18877	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1606768|imex:IM-18877-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_181626.1|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003018(GAF)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|rcsb pdb:4MT8|rcsb pdb:4MTX|ensemblplants:AT2G40940(gene)|interpro:IPR029016|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051740"(ethylene binding)|ensemblplants:AT2G40940.1(transcript)|interpro:IPR036097|interpro:IPR036890	refseq:NP_195993.1|refseq:NP_850760.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|rcsb pdb:3P86|rcsb pdb:3PPZ|ensemblplants:AT5G03730(gene)|ensemblplants:AT5G03730.1(transcript)|ensemblplants:AT5G03730.2(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0009686"(gibberellin biosynthetic process)|go:"GO:0009723"(response to ethylene)|go:"GO:0009744"(response to sucrose)|go:"GO:0009750"(response to fructose)|go:"GO:0009873"(ethylene-activated signaling pathway)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048510"(regulation of timing of transition from vegetative to reproductive phase)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000069"(regulation of post-embryonic root development)|interpro:IPR028324	-	-	-	figure legend:Figure 1B and 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/22	2014/10/16	rogid:YWQgcm36eoN4fz7TlLzn4LP7Uts3702	rogid:alzKx+H+r2/qYHnthzzURxvJlic3702	intact-crc:C0001FC299639D41|rigid:wIZH05hlcBgYCi8Ow32ExK+I/qk	false	sufficient binding region:261-613	sufficient binding region:171-521	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P49333	uniprotkb:Q05609	intact:EBI-1606682|ensemblplants:AT1G66340.1	intact:EBI-1606697|ensemblplants:AT5G03730.1|ensemblplants:AT5G03730.2	psi-mi:etr1_arath(display_long)|uniprotkb:ETR1(gene name)|psi-mi:ETR1(display_short)|uniprotkb:T27F4.9(orf name)|uniprotkb:At1g66340(locus name)|uniprotkb:Protein ETHYLENE RESPONSE 1(gene name synonym)|uniprotkb:Protein ETR1(gene name synonym)	psi-mi:ctr1_arath(display_long)|uniprotkb:Protein CONSTITUTIVE TRIPLE RESPONSE1(gene name synonym)|uniprotkb:F17C15_150(orf name)|uniprotkb:CTR1(gene name)|psi-mi:CTR1(display_short)|uniprotkb:At5g03730(locus name)	psi-mi:"MI:0018"(two hybrid)	Clark et al. (1998)	pubmed:9560288|imex:IM-18877	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1606791|imex:IM-18877-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4PL9|refseq:NP_176808.3|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011006(CheY-like)|interpro:IPR003018(GAF)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR014525(Signal transduction histidine kinase, hybrid-type, ethylene sensor)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR001789(Signal transduction response regulator, receiver region)|rcsb pdb:1DCF|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009739"(response to gibberellin)|go:"GO:0010087"(phloem or xylem histogenesis)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0010119"(regulation of stomatal movement)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0051740"(ethylene binding)|go:"GO:0052544"(defense response by callose deposition in cell wall)|go:"GO:1900140"(regulation of seedling development)|interpro:IPR029016|ensemblplants:AT1G66340(gene)|ensemblplants:AT1G66340.1(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0009408"(response to heat)|go:"GO:0009625"(response to insect)|go:"GO:0009651"(response to salt stress)|go:"GO:0009690"(cytokinin metabolic process)|go:"GO:0009723"(response to ethylene)|go:"GO:0009727"(detection of ethylene stimulus)|go:"GO:0009733"(response to auxin)|interpro:IPR036097|interpro:IPR036890	refseq:NP_195993.1|refseq:NP_850760.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|rcsb pdb:3P86|rcsb pdb:3PPZ|ensemblplants:AT5G03730(gene)|ensemblplants:AT5G03730.1(transcript)|ensemblplants:AT5G03730.2(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0009686"(gibberellin biosynthetic process)|go:"GO:0009723"(response to ethylene)|go:"GO:0009744"(response to sucrose)|go:"GO:0009750"(response to fructose)|go:"GO:0009873"(ethylene-activated signaling pathway)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048510"(regulation of timing of transition from vegetative to reproductive phase)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000069"(regulation of post-embryonic root development)|interpro:IPR028324	-	-	-	figure legend:Figure 1A, Figure 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/22	2014/10/16	rogid:HU7HG7EHvZR/6trEt2M2wmFdHRY3702	rogid:alzKx+H+r2/qYHnthzzURxvJlic3702	intact-crc:ED79E90D22A83508|rigid:X89ylCUBHbsvXePqH1hwyXlmcvY	false	sufficient binding region:293-729	sufficient binding region:171-521	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P49333	uniprotkb:Q05609	intact:EBI-1606682|ensemblplants:AT1G66340.1	intact:EBI-1606697|ensemblplants:AT5G03730.1|ensemblplants:AT5G03730.2	psi-mi:etr1_arath(display_long)|uniprotkb:ETR1(gene name)|psi-mi:ETR1(display_short)|uniprotkb:T27F4.9(orf name)|uniprotkb:At1g66340(locus name)|uniprotkb:Protein ETHYLENE RESPONSE 1(gene name synonym)|uniprotkb:Protein ETR1(gene name synonym)	psi-mi:ctr1_arath(display_long)|uniprotkb:Protein CONSTITUTIVE TRIPLE RESPONSE1(gene name synonym)|uniprotkb:F17C15_150(orf name)|uniprotkb:CTR1(gene name)|psi-mi:CTR1(display_short)|uniprotkb:At5g03730(locus name)	psi-mi:"MI:0096"(pull down)	Clark et al. (1998)	pubmed:9560288|imex:IM-18877	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1606850|imex:IM-18877-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4PL9|refseq:NP_176808.3|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011006(CheY-like)|interpro:IPR003018(GAF)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR014525(Signal transduction histidine kinase, hybrid-type, ethylene sensor)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR001789(Signal transduction response regulator, receiver region)|rcsb pdb:1DCF|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009739"(response to gibberellin)|go:"GO:0010087"(phloem or xylem histogenesis)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0010119"(regulation of stomatal movement)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0051740"(ethylene binding)|go:"GO:0052544"(defense response by callose deposition in cell wall)|go:"GO:1900140"(regulation of seedling development)|interpro:IPR029016|ensemblplants:AT1G66340(gene)|ensemblplants:AT1G66340.1(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0009408"(response to heat)|go:"GO:0009625"(response to insect)|go:"GO:0009651"(response to salt stress)|go:"GO:0009690"(cytokinin metabolic process)|go:"GO:0009723"(response to ethylene)|go:"GO:0009727"(detection of ethylene stimulus)|go:"GO:0009733"(response to auxin)|interpro:IPR036097|interpro:IPR036890	refseq:NP_195993.1|refseq:NP_850760.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|rcsb pdb:3P86|rcsb pdb:3PPZ|ensemblplants:AT5G03730(gene)|ensemblplants:AT5G03730.1(transcript)|ensemblplants:AT5G03730.2(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0009686"(gibberellin biosynthetic process)|go:"GO:0009723"(response to ethylene)|go:"GO:0009744"(response to sucrose)|go:"GO:0009750"(response to fructose)|go:"GO:0009873"(ethylene-activated signaling pathway)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048510"(regulation of timing of transition from vegetative to reproductive phase)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000069"(regulation of post-embryonic root development)|interpro:IPR028324	-	-	-	figure legend:Figure 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/22	2014/10/16	rogid:HU7HG7EHvZR/6trEt2M2wmFdHRY3702	rogid:alzKx+H+r2/qYHnthzzURxvJlic3702	intact-crc:298C0A58F62EE986|rigid:X89ylCUBHbsvXePqH1hwyXlmcvY	false	maltose binding protein tag:?-?|binding-associated region:293-610	sufficient binding region:171-521	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49333	uniprotkb:Q05609	intact:EBI-1606682|ensemblplants:AT1G66340.1	intact:EBI-1606697|ensemblplants:AT5G03730.1|ensemblplants:AT5G03730.2	psi-mi:etr1_arath(display_long)|uniprotkb:ETR1(gene name)|psi-mi:ETR1(display_short)|uniprotkb:T27F4.9(orf name)|uniprotkb:At1g66340(locus name)|uniprotkb:Protein ETHYLENE RESPONSE 1(gene name synonym)|uniprotkb:Protein ETR1(gene name synonym)	psi-mi:ctr1_arath(display_long)|uniprotkb:Protein CONSTITUTIVE TRIPLE RESPONSE1(gene name synonym)|uniprotkb:F17C15_150(orf name)|uniprotkb:CTR1(gene name)|psi-mi:CTR1(display_short)|uniprotkb:At5g03730(locus name)	psi-mi:"MI:0096"(pull down)	Clark et al. (1998)	pubmed:9560288|imex:IM-18877	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1606861|imex:IM-18877-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4PL9|refseq:NP_176808.3|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011006(CheY-like)|interpro:IPR003018(GAF)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR014525(Signal transduction histidine kinase, hybrid-type, ethylene sensor)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR001789(Signal transduction response regulator, receiver region)|rcsb pdb:1DCF|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009739"(response to gibberellin)|go:"GO:0010087"(phloem or xylem histogenesis)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0010119"(regulation of stomatal movement)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0051740"(ethylene binding)|go:"GO:0052544"(defense response by callose deposition in cell wall)|go:"GO:1900140"(regulation of seedling development)|interpro:IPR029016|ensemblplants:AT1G66340(gene)|ensemblplants:AT1G66340.1(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0009408"(response to heat)|go:"GO:0009625"(response to insect)|go:"GO:0009651"(response to salt stress)|go:"GO:0009690"(cytokinin metabolic process)|go:"GO:0009723"(response to ethylene)|go:"GO:0009727"(detection of ethylene stimulus)|go:"GO:0009733"(response to auxin)|interpro:IPR036097|interpro:IPR036890	refseq:NP_195993.1|refseq:NP_850760.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|rcsb pdb:3P86|rcsb pdb:3PPZ|ensemblplants:AT5G03730(gene)|ensemblplants:AT5G03730.1(transcript)|ensemblplants:AT5G03730.2(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0009686"(gibberellin biosynthetic process)|go:"GO:0009723"(response to ethylene)|go:"GO:0009744"(response to sucrose)|go:"GO:0009750"(response to fructose)|go:"GO:0009873"(ethylene-activated signaling pathway)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048510"(regulation of timing of transition from vegetative to reproductive phase)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000069"(regulation of post-embryonic root development)|interpro:IPR028324	-	-	-	figure legend:Figure 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/22	2014/10/16	rogid:HU7HG7EHvZR/6trEt2M2wmFdHRY3702	rogid:alzKx+H+r2/qYHnthzzURxvJlic3702	intact-crc:D96EA098FB537311|rigid:X89ylCUBHbsvXePqH1hwyXlmcvY	false	sufficient binding region:293-610	sufficient binding region:53-568|maltose binding protein tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q05609	uniprotkb:Q38846	intact:EBI-1606697|ensemblplants:AT5G03730.1|ensemblplants:AT5G03730.2	intact:EBI-1606754|ensemblplants:AT2G40940.1	psi-mi:ctr1_arath(display_long)|uniprotkb:Protein CONSTITUTIVE TRIPLE RESPONSE1(gene name synonym)|uniprotkb:F17C15_150(orf name)|uniprotkb:CTR1(gene name)|psi-mi:CTR1(display_short)|uniprotkb:At5g03730(locus name)	psi-mi:ers1_arath(display_long)|uniprotkb:ERS1(gene name)|psi-mi:ERS1(display_short)|uniprotkb:ERS(gene name synonym)|uniprotkb:At2g40940(locus name)|uniprotkb:Protein ERS1(gene name synonym)|uniprotkb:T20B5.14(orf name)	psi-mi:"MI:0096"(pull down)	Clark et al. (1998)	pubmed:9560288|imex:IM-18877	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1606874|imex:IM-18877-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_195993.1|refseq:NP_850760.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|rcsb pdb:3P86|rcsb pdb:3PPZ|ensemblplants:AT5G03730(gene)|ensemblplants:AT5G03730.1(transcript)|ensemblplants:AT5G03730.2(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0009686"(gibberellin biosynthetic process)|go:"GO:0009723"(response to ethylene)|go:"GO:0009744"(response to sucrose)|go:"GO:0009750"(response to fructose)|go:"GO:0009873"(ethylene-activated signaling pathway)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048510"(regulation of timing of transition from vegetative to reproductive phase)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000069"(regulation of post-embryonic root development)|interpro:IPR028324	refseq:NP_181626.1|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003018(GAF)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|rcsb pdb:4MT8|rcsb pdb:4MTX|ensemblplants:AT2G40940(gene)|interpro:IPR029016|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051740"(ethylene binding)|ensemblplants:AT2G40940.1(transcript)|interpro:IPR036097|interpro:IPR036890	-	-	-	figure legend:Figure 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/22	2014/10/16	rogid:alzKx+H+r2/qYHnthzzURxvJlic3702	rogid:YWQgcm36eoN4fz7TlLzn4LP7Uts3702	intact-crc:05414F8925082404|rigid:wIZH05hlcBgYCi8Ow32ExK+I/qk	false	maltose binding protein tag:?-?|sufficient binding region:53-568	sufficient binding region:261-613	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q05609	uniprotkb:P49333	intact:EBI-1606697|ensemblplants:AT5G03730.1|ensemblplants:AT5G03730.2	intact:EBI-1606682|ensemblplants:AT1G66340.1	psi-mi:ctr1_arath(display_long)|uniprotkb:Protein CONSTITUTIVE TRIPLE RESPONSE1(gene name synonym)|uniprotkb:F17C15_150(orf name)|uniprotkb:CTR1(gene name)|psi-mi:CTR1(display_short)|uniprotkb:At5g03730(locus name)	psi-mi:etr1_arath(display_long)|uniprotkb:ETR1(gene name)|psi-mi:ETR1(display_short)|uniprotkb:T27F4.9(orf name)|uniprotkb:At1g66340(locus name)|uniprotkb:Protein ETHYLENE RESPONSE 1(gene name synonym)|uniprotkb:Protein ETR1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Clark et al. (1998)	pubmed:9560288|imex:IM-18877	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1606891|imex:IM-18877-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_195993.1|refseq:NP_850760.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|rcsb pdb:3P86|rcsb pdb:3PPZ|ensemblplants:AT5G03730(gene)|ensemblplants:AT5G03730.1(transcript)|ensemblplants:AT5G03730.2(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0009686"(gibberellin biosynthetic process)|go:"GO:0009723"(response to ethylene)|go:"GO:0009744"(response to sucrose)|go:"GO:0009750"(response to fructose)|go:"GO:0009873"(ethylene-activated signaling pathway)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048510"(regulation of timing of transition from vegetative to reproductive phase)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000069"(regulation of post-embryonic root development)|interpro:IPR028324	rcsb pdb:4PL9|refseq:NP_176808.3|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011006(CheY-like)|interpro:IPR003018(GAF)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR014525(Signal transduction histidine kinase, hybrid-type, ethylene sensor)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR001789(Signal transduction response regulator, receiver region)|rcsb pdb:1DCF|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009739"(response to gibberellin)|go:"GO:0010087"(phloem or xylem histogenesis)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0010119"(regulation of stomatal movement)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0051740"(ethylene binding)|go:"GO:0052544"(defense response by callose deposition in cell wall)|go:"GO:1900140"(regulation of seedling development)|interpro:IPR029016|ensemblplants:AT1G66340(gene)|ensemblplants:AT1G66340.1(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0009408"(response to heat)|go:"GO:0009625"(response to insect)|go:"GO:0009651"(response to salt stress)|go:"GO:0009690"(cytokinin metabolic process)|go:"GO:0009723"(response to ethylene)|go:"GO:0009727"(detection of ethylene stimulus)|go:"GO:0009733"(response to auxin)|interpro:IPR036097|interpro:IPR036890	-	-	-	figure legend:Figure 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/22	2014/10/16	rogid:alzKx+H+r2/qYHnthzzURxvJlic3702	rogid:HU7HG7EHvZR/6trEt2M2wmFdHRY3702	intact-crc:22FA933A564C7013|rigid:X89ylCUBHbsvXePqH1hwyXlmcvY	false	sufficient binding region:53-568|35s radiolabel:?-?	maltose binding protein tag:?-?|sufficient binding region:293-610	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q05609	uniprotkb:O22267	intact:EBI-1606697|ensemblplants:AT5G03730.1|ensemblplants:AT5G03730.2	intact:EBI-1606904|uniprotkb:A5YY37|ensemblplants:AT2G47430.1	psi-mi:ctr1_arath(display_long)|uniprotkb:Protein CONSTITUTIVE TRIPLE RESPONSE1(gene name synonym)|uniprotkb:F17C15_150(orf name)|uniprotkb:CTR1(gene name)|psi-mi:CTR1(display_short)|uniprotkb:At5g03730(locus name)	psi-mi:cki1_arath(display_long)|uniprotkb:CKI1(gene name)|psi-mi:CKI1(display_short)|uniprotkb:At2g47430(locus name)|uniprotkb:Protein CYTOKININ-INDEPENDENT 1(gene name synonym)|uniprotkb:T30B22.27(orf name)	psi-mi:"MI:0096"(pull down)	Clark et al. (1998)	pubmed:9560288|imex:IM-18877	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1606916|imex:IM-18877-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_195993.1|refseq:NP_850760.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|rcsb pdb:3P86|rcsb pdb:3PPZ|ensemblplants:AT5G03730(gene)|ensemblplants:AT5G03730.1(transcript)|ensemblplants:AT5G03730.2(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0009686"(gibberellin biosynthetic process)|go:"GO:0009723"(response to ethylene)|go:"GO:0009744"(response to sucrose)|go:"GO:0009750"(response to fructose)|go:"GO:0009873"(ethylene-activated signaling pathway)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048510"(regulation of timing of transition from vegetative to reproductive phase)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000069"(regulation of post-embryonic root development)|interpro:IPR028324	refseq:NP_182265.1|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011006(CheY-like)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR001789(Signal transduction response regulator, receiver region)|rcsb pdb:3MM4|rcsb pdb:3MMN|ensemblplants:AT2G47430(gene)|ensemblplants:AT2G47430.1(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0009506"(plasmodesma)|go:"GO:0009553"(embryo sac development)|go:"GO:0009736"(cytokinin-activated signaling pathway)|go:"GO:0010087"(phloem or xylem histogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0080117"(secondary growth)|interpro:IPR036097|interpro:IPR036890|rcsb pdb:5LNM|rcsb pdb:5LNN|rcsb pdb:5N2N	-	-	-	figure legend:Figure 5A|caution:"The authors state \"Of note, when the amount of added radiolabeled CTR1 protein was increased 5-fold, the interaction with MBP-ETR increased whereas the apparent weak association with MBP alone was not enhanced significantly. The absence of association with the CKI1 receiver is indicative of the specificity of the CTR1 association with the ETR1 receiver\"."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/22	2014/10/16	rogid:alzKx+H+r2/qYHnthzzURxvJlic3702	rogid:dZw6s6E6xaKOuDEbL6177MYrhKg3702	intact-crc:80CD5A15CC394A63|rigid:BPG+IWUdM7Tnto+1QtQmvRiNzj4	false	sufficient binding region:53-568|35s radiolabel:?-?	maltose binding protein tag:?-?|sufficient binding region:981-1122	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)