#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P32479	uniprotkb:P32479	intact:EBI-8316|uniprotkb:D6VPZ2|ensemblfungi:YBL008W	intact:EBI-8316|uniprotkb:D6VPZ2|ensemblfungi:YBL008W	psi-mi:hir1_yeast(display_long)|uniprotkb:HIR1(gene name)|psi-mi:HIR1(display_short)|uniprotkb:YBL008W(locus name)|uniprotkb:YBL0318(orf name)|uniprotkb:Histone transcription regulator 1(gene name synonym)	psi-mi:hir1_yeast(display_long)|uniprotkb:HIR1(gene name)|psi-mi:HIR1(display_short)|uniprotkb:YBL008W(locus name)|uniprotkb:YBL0318(orf name)|uniprotkb:Histone transcription regulator 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	DeSilva et al. (1998)	pubmed:9504914|imex:IM-19471	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2123950|imex:IM-19471-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009545.2|sgd:S000000104|mint:P32479|dip:DIP-2365N|ensemblfungi:YBL008W(gene)|ensemblfungi:YBL008W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000417"(HIR complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0042802"(identical protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR011494(TUP1-like enhancer of split)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019015|interpro:IPR031120|interpro:IPR036322|reactome:R-SCE-2559584	refseq:NP_009545.2|sgd:S000000104|mint:P32479|dip:DIP-2365N|ensemblfungi:YBL008W(gene)|ensemblfungi:YBL008W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000417"(HIR complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0042802"(identical protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR011494(TUP1-like enhancer of split)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019015|interpro:IPR031120|interpro:IPR036322|reactome:R-SCE-2559584	-	crc64:40A2932F3306358A	crc64:40A2932F3306358A	figure legend:Fig. 2A|comment:Both C-termnus and N-terminus binding sites are sufficient for the interaction.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/12/04	2014/10/16	rogid:z8DaVpRlA0M66kI+KB4/rJekKrw559292	rogid:z8DaVpRlA0M66kI+KB4/rJekKrw559292	intact-crc:E3EEE8F94FD4B1B4|rigid:M5DIzSDIjkBDf9RLC8jZ+lYxmO4	false	ha tag:?-?	sufficient binding region:1-389(IPR001680)|fusion protein:n-n|sufficient binding region:392-840	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32480	uniprotkb:P32479	intact:EBI-8323|uniprotkb:D6W2A5|ensemblfungi:YOR038C	intact:EBI-8316|uniprotkb:D6VPZ2|ensemblfungi:YBL008W	psi-mi:hir2_yeast(display_long)|uniprotkb:HIR2(gene name)|psi-mi:HIR2(display_short)|uniprotkb:YOR038C(locus name)|uniprotkb:OR26.31(orf name)|uniprotkb:Histone transcription regulator 2(gene name synonym)	psi-mi:hir1_yeast(display_long)|uniprotkb:HIR1(gene name)|psi-mi:HIR1(display_short)|uniprotkb:YBL008W(locus name)|uniprotkb:YBL0318(orf name)|uniprotkb:Histone transcription regulator 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	DeSilva et al. (1998)	pubmed:9504914|imex:IM-19471	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2123970|imex:IM-19471-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014681.1|sgd:S000005564|mint:P32480|dip:DIP-2366N|ensemblfungi:YOR038C(gene)|ensemblfungi:YOR038C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000417"(HIR complex)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|interpro:IPR011494(TUP1-like enhancer of split)|interpro:IPR031120|interpro:IPR036322	refseq:NP_009545.2|sgd:S000000104|mint:P32479|dip:DIP-2365N|ensemblfungi:YBL008W(gene)|ensemblfungi:YBL008W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000417"(HIR complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0042802"(identical protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR011494(TUP1-like enhancer of split)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019015|interpro:IPR031120|interpro:IPR036322|reactome:R-SCE-2559584	-	crc64:C77D677BF424680D	crc64:40A2932F3306358A	figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/12/04	2014/10/16	rogid:QhQfVbm7uHiW5zk9XHvVz2mJWYw559292	rogid:z8DaVpRlA0M66kI+KB4/rJekKrw559292	intact-crc:4D01712DD2E3DC8A|rigid:TnAVVmcsg1ShQZbm3xsASccsTsM	false	ha tag:?-?	binding-associated region:392-840|fusion protein:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32479	uniprotkb:P32914	intact:EBI-8316|uniprotkb:D6VPZ2|ensemblfungi:YBL008W	intact:EBI-17928|uniprotkb:D6VUJ8|uniprotkb:Q0P6T7|uniprotkb:Q45U23|ensemblfungi:YGR063C	psi-mi:hir1_yeast(display_long)|uniprotkb:HIR1(gene name)|psi-mi:HIR1(display_short)|uniprotkb:YBL008W(locus name)|uniprotkb:YBL0318(orf name)|uniprotkb:Histone transcription regulator 1(gene name synonym)	psi-mi:spt4_yeast(display_long)|uniprotkb:YGR063C(locus name)|uniprotkb:SPT4(gene name)|psi-mi:SPT4(display_short)|uniprotkb:Chromatin elongation factor SPT4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	DeSilva et al. (1998)	pubmed:9504914|imex:IM-19471	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2123994|imex:IM-19471-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009545.2|sgd:S000000104|mint:P32479|dip:DIP-2365N|ensemblfungi:YBL008W(gene)|ensemblfungi:YBL008W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000417"(HIR complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0042802"(identical protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR011494(TUP1-like enhancer of split)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019015|interpro:IPR031120|interpro:IPR036322|reactome:R-SCE-2559584	sgd:S000003295|ensemblfungi:YGR063C(gene)|ensemblfungi:YGR063C_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006397"(mRNA processing)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR009287(Transcription initiation Spt4)|interpro:IPR022800|interpro:IPR029040|interpro:IPR038510|rcsb pdb:2EXU|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-75955|refseq:NP_011577.3|dip:DIP-2078N|mint:P32914	-	crc64:40A2932F3306358A	crc64:59C164193ABA883B	figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/12/04	2014/10/16	rogid:z8DaVpRlA0M66kI+KB4/rJekKrw559292	rogid:MC4Di+maCZ0kgCpzXXV0KP82pwU559292	intact-crc:516C374812E0E668|rigid:kzUmfyDwPvF0LqYS4VTRLSvwRz0	false	fusion protein:n-n	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32479	uniprotkb:P32914	intact:EBI-8316|uniprotkb:D6VPZ2|ensemblfungi:YBL008W	intact:EBI-17928|uniprotkb:D6VUJ8|uniprotkb:Q0P6T7|uniprotkb:Q45U23|ensemblfungi:YGR063C	psi-mi:hir1_yeast(display_long)|uniprotkb:HIR1(gene name)|psi-mi:HIR1(display_short)|uniprotkb:YBL008W(locus name)|uniprotkb:YBL0318(orf name)|uniprotkb:Histone transcription regulator 1(gene name synonym)	psi-mi:spt4_yeast(display_long)|uniprotkb:YGR063C(locus name)|uniprotkb:SPT4(gene name)|psi-mi:SPT4(display_short)|uniprotkb:Chromatin elongation factor SPT4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	DeSilva et al. (1998)	pubmed:9504914|imex:IM-19471	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2124004|imex:IM-19471-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009545.2|sgd:S000000104|mint:P32479|dip:DIP-2365N|ensemblfungi:YBL008W(gene)|ensemblfungi:YBL008W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000417"(HIR complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0042802"(identical protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR011494(TUP1-like enhancer of split)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019015|interpro:IPR031120|interpro:IPR036322|reactome:R-SCE-2559584	sgd:S000003295|ensemblfungi:YGR063C(gene)|ensemblfungi:YGR063C_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006397"(mRNA processing)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR009287(Transcription initiation Spt4)|interpro:IPR022800|interpro:IPR029040|interpro:IPR038510|rcsb pdb:2EXU|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-75955|refseq:NP_011577.3|dip:DIP-2078N|mint:P32914	-	crc64:40A2932F3306358A	crc64:59C164193ABA883B	figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/12/04	2014/10/16	rogid:z8DaVpRlA0M66kI+KB4/rJekKrw559292	rogid:MC4Di+maCZ0kgCpzXXV0KP82pwU559292	intact-crc:C9C9D48997D583DA|rigid:kzUmfyDwPvF0LqYS4VTRLSvwRz0	false	ha tag:?-?	fusion protein:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)