#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P55861 uniprotkb:P49739 intact:EBI-876864|uniprotkb:O42588|uniprotkb:Q7ZX05 intact:EBI-491720|uniprotkb:Q2NL58|uniprotkb:Q91919 psi-mi:mcm2_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:BM28-homolog(gene name synonym)|uniprotkb:p112(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short) psi-mi:mcm3m_xenla(display_long)|uniprotkb:Maternal minichromosome maintenance protein 3(gene name synonym)|uniprotkb:P1 homolog(gene name synonym)|uniprotkb:p100(gene name synonym)|uniprotkb:XRLF subunit beta(gene name synonym)|uniprotkb:mmcm3(gene name)|psi-mi:mmcm3(display_short) psi-mi:"MI:0091"(chromatography technology) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR027925|refseq:NP_001080759.1|interpro:IPR008045(MCM protein 2)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55861|interpro:IPR041562 interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001081412.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR018525|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR031327|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|mint:P49739|interpro:IPR041562 - - - figure legend:1 and 2A, 4C, 4D|comment:Simmilar results were observed in RLF-M compelxes.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:BKavzWA0OlaUmzbdJtq74Bk9qKM8355 rogid:LBdvRzij5a5buPkt/86l4Tl4HcE8355 intact-crc:77289760267123DE|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P55861 uniprotkb:Q5XK83 intact:EBI-876864|uniprotkb:O42588|uniprotkb:Q7ZX05 intact:EBI-1789370|uniprotkb:O42589 psi-mi:mcm2_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:BM28-homolog(gene name synonym)|uniprotkb:p112(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short) psi-mi:mcm4a_xenla(display_long)|uniprotkb:mcm4-a(gene name)|psi-mi:mcm4-a(display_short)|uniprotkb:Minichromosome maintenance protein 4-A(gene name synonym)|uniprotkb:CDC21 homolog-A(gene name synonym)|uniprotkb:P1-CDC21-A(gene name synonym)|uniprotkb:p98(gene name synonym) psi-mi:"MI:0091"(chromatography technology) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR027925|refseq:NP_001080759.1|interpro:IPR008045(MCM protein 2)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55861|interpro:IPR041562 interpro:IPR033762|refseq:NP_001079069.1|interpro:IPR008047(MCM protein 4)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027925|interpro:IPR027417|mint:Q5XK83|interpro:IPR041562|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity) - - - figure legend:1 and 2A, 4C, 4D|comment:Simmilar results were observed in RLF-M compelxes.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:BKavzWA0OlaUmzbdJtq74Bk9qKM8355 rogid:VBIiuJghubSRemwMGVBc8alovhI8355 intact-crc:77289760267123DE|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P55861 uniprotkb:P55862 intact:EBI-876864|uniprotkb:O42588|uniprotkb:Q7ZX05 intact:EBI-876879|uniprotkb:Q5D0A3 psi-mi:mcm2_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:BM28-homolog(gene name synonym)|uniprotkb:p112(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short) psi-mi:mcm5a_xenla(display_long)|uniprotkb:CDC46 homolog A(gene name synonym)|uniprotkb:CDC46p(gene name synonym)|uniprotkb:p92(gene name synonym)|uniprotkb:mcm5-a(gene name)|psi-mi:mcm5-a(display_short)|uniprotkb:cdc46-a(gene name synonym) psi-mi:"MI:0091"(chromatography technology) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR027925|refseq:NP_001080759.1|interpro:IPR008045(MCM protein 2)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55861|interpro:IPR041562 go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR027925|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001080893.1|interpro:IPR008048(MCM protein 5)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55862|interpro:IPR041562 - - - figure legend:1 and 2A, 4C, 4D|comment:Simmilar results were observed in RLF-M compelxes.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:BKavzWA0OlaUmzbdJtq74Bk9qKM8355 rogid:2AhC8Mo3s9VuusyTSZ0yryyL0ok8355 intact-crc:77289760267123DE|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P55861 uniprotkb:Q5FWY4 intact:EBI-876864|uniprotkb:O42588|uniprotkb:Q7ZX05 intact:EBI-1789358|uniprotkb:O42590 psi-mi:mcm2_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:BM28-homolog(gene name synonym)|uniprotkb:p112(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short) psi-mi:mcm6m_xenla(display_long)|uniprotkb:mmcm6(gene name)|psi-mi:mmcm6(display_short)|uniprotkb:Maternal minichromosome maintenance protein 6(gene name synonym) psi-mi:"MI:0091"(chromatography technology) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR027925|refseq:NP_001080759.1|interpro:IPR008045(MCM protein 2)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55861|interpro:IPR041562 interpro:IPR033762|refseq:NP_001081822.1|interpro:IPR008049(MCM protein 6)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027925|interpro:IPR027417|interpro:IPR041024|interpro:IPR041562|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity) - - - figure legend:1 and 2A, 4C, 4D|comment:Simmilar results were observed in RLF-M compelxes.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:BKavzWA0OlaUmzbdJtq74Bk9qKM8355 rogid:jlU3T5P3p9NkbPuq7CADRoBDNTc8355 intact-crc:77289760267123DE|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P55861 uniprotkb:Q91876 intact:EBI-876864|uniprotkb:O42588|uniprotkb:Q7ZX05 intact:EBI-876852|uniprotkb:O42591|uniprotkb:Q6GQ16 psi-mi:mcm2_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:BM28-homolog(gene name synonym)|uniprotkb:p112(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short) psi-mi:mcm7a_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 7-A(gene name synonym)|uniprotkb:CDC47 homolog A(gene name synonym)|uniprotkb:CDC47p(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:mcm7-a(gene name)|psi-mi:mcm7-a(display_short)|uniprotkb:cdc47(gene name synonym) psi-mi:"MI:0091"(chromatography technology) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR027925|refseq:NP_001080759.1|interpro:IPR008045(MCM protein 2)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55861|interpro:IPR041562 go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR027925|refseq:NP_001081466.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:Q91876|interpro:IPR041562 - - - figure legend:1 and 2A, 4C, 4D|comment:Simmilar results were observed in RLF-M compelxes.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:BKavzWA0OlaUmzbdJtq74Bk9qKM8355 rogid:IPLvcG4PDdfeYmVQhOOHEVSG1+s8355 intact-crc:77289760267123DE|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49739 uniprotkb:Q91876 intact:EBI-491720|uniprotkb:Q2NL58|uniprotkb:Q91919 intact:EBI-876852|uniprotkb:O42591|uniprotkb:Q6GQ16 psi-mi:mcm3m_xenla(display_long)|uniprotkb:Maternal minichromosome maintenance protein 3(gene name synonym)|uniprotkb:P1 homolog(gene name synonym)|uniprotkb:p100(gene name synonym)|uniprotkb:XRLF subunit beta(gene name synonym)|uniprotkb:mmcm3(gene name)|psi-mi:mmcm3(display_short) psi-mi:mcm7a_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 7-A(gene name synonym)|uniprotkb:CDC47 homolog A(gene name synonym)|uniprotkb:CDC47p(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:mcm7-a(gene name)|psi-mi:mcm7-a(display_short)|uniprotkb:cdc47(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789461 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001081412.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR018525|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR031327|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|mint:P49739|interpro:IPR041562 go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR027925|refseq:NP_001081466.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:Q91876|interpro:IPR041562 - - - figure legend:2B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:LBdvRzij5a5buPkt/86l4Tl4HcE8355 rogid:IPLvcG4PDdfeYmVQhOOHEVSG1+s8355 intact-crc:F289F8269104D8DD|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49739 uniprotkb:P55862 intact:EBI-491720|uniprotkb:Q2NL58|uniprotkb:Q91919 intact:EBI-876879|uniprotkb:Q5D0A3 psi-mi:mcm3m_xenla(display_long)|uniprotkb:Maternal minichromosome maintenance protein 3(gene name synonym)|uniprotkb:P1 homolog(gene name synonym)|uniprotkb:p100(gene name synonym)|uniprotkb:XRLF subunit beta(gene name synonym)|uniprotkb:mmcm3(gene name)|psi-mi:mmcm3(display_short) psi-mi:mcm5a_xenla(display_long)|uniprotkb:CDC46 homolog A(gene name synonym)|uniprotkb:CDC46p(gene name synonym)|uniprotkb:p92(gene name synonym)|uniprotkb:mcm5-a(gene name)|psi-mi:mcm5-a(display_short)|uniprotkb:cdc46-a(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789461 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001081412.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR018525|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR031327|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|mint:P49739|interpro:IPR041562 go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR027925|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001080893.1|interpro:IPR008048(MCM protein 5)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55862|interpro:IPR041562 - - - figure legend:2B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:LBdvRzij5a5buPkt/86l4Tl4HcE8355 rogid:2AhC8Mo3s9VuusyTSZ0yryyL0ok8355 intact-crc:F289F8269104D8DD|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49739 uniprotkb:Q5XK83 intact:EBI-491720|uniprotkb:Q2NL58|uniprotkb:Q91919 intact:EBI-1789370|uniprotkb:O42589 psi-mi:mcm3m_xenla(display_long)|uniprotkb:Maternal minichromosome maintenance protein 3(gene name synonym)|uniprotkb:P1 homolog(gene name synonym)|uniprotkb:p100(gene name synonym)|uniprotkb:XRLF subunit beta(gene name synonym)|uniprotkb:mmcm3(gene name)|psi-mi:mmcm3(display_short) psi-mi:mcm4a_xenla(display_long)|uniprotkb:mcm4-a(gene name)|psi-mi:mcm4-a(display_short)|uniprotkb:Minichromosome maintenance protein 4-A(gene name synonym)|uniprotkb:CDC21 homolog-A(gene name synonym)|uniprotkb:P1-CDC21-A(gene name synonym)|uniprotkb:p98(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789461 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001081412.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR018525|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR031327|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|mint:P49739|interpro:IPR041562 interpro:IPR033762|refseq:NP_001079069.1|interpro:IPR008047(MCM protein 4)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027925|interpro:IPR027417|mint:Q5XK83|interpro:IPR041562|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity) - - - figure legend:2B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:LBdvRzij5a5buPkt/86l4Tl4HcE8355 rogid:VBIiuJghubSRemwMGVBc8alovhI8355 intact-crc:F289F8269104D8DD|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49739 uniprotkb:P55861 intact:EBI-491720|uniprotkb:Q2NL58|uniprotkb:Q91919 intact:EBI-876864|uniprotkb:O42588|uniprotkb:Q7ZX05 psi-mi:mcm3m_xenla(display_long)|uniprotkb:Maternal minichromosome maintenance protein 3(gene name synonym)|uniprotkb:P1 homolog(gene name synonym)|uniprotkb:p100(gene name synonym)|uniprotkb:XRLF subunit beta(gene name synonym)|uniprotkb:mmcm3(gene name)|psi-mi:mmcm3(display_short) psi-mi:mcm2_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:BM28-homolog(gene name synonym)|uniprotkb:p112(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789461 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001081412.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR018525|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR031327|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|mint:P49739|interpro:IPR041562 go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR027925|refseq:NP_001080759.1|interpro:IPR008045(MCM protein 2)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55861|interpro:IPR041562 - - - figure legend:2B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:LBdvRzij5a5buPkt/86l4Tl4HcE8355 rogid:BKavzWA0OlaUmzbdJtq74Bk9qKM8355 intact-crc:F289F8269104D8DD|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49739 uniprotkb:Q5FWY4 intact:EBI-491720|uniprotkb:Q2NL58|uniprotkb:Q91919 intact:EBI-1789358|uniprotkb:O42590 psi-mi:mcm3m_xenla(display_long)|uniprotkb:Maternal minichromosome maintenance protein 3(gene name synonym)|uniprotkb:P1 homolog(gene name synonym)|uniprotkb:p100(gene name synonym)|uniprotkb:XRLF subunit beta(gene name synonym)|uniprotkb:mmcm3(gene name)|psi-mi:mmcm3(display_short) psi-mi:mcm6m_xenla(display_long)|uniprotkb:mmcm6(gene name)|psi-mi:mmcm6(display_short)|uniprotkb:Maternal minichromosome maintenance protein 6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789461 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001081412.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR018525|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR031327|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|mint:P49739|interpro:IPR041562 interpro:IPR033762|refseq:NP_001081822.1|interpro:IPR008049(MCM protein 6)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027925|interpro:IPR027417|interpro:IPR041024|interpro:IPR041562|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity) - - - figure legend:2B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:LBdvRzij5a5buPkt/86l4Tl4HcE8355 rogid:jlU3T5P3p9NkbPuq7CADRoBDNTc8355 intact-crc:F289F8269104D8DD|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49739 uniprotkb:P55861 intact:EBI-491720|uniprotkb:Q2NL58|uniprotkb:Q91919 intact:EBI-876864|uniprotkb:O42588|uniprotkb:Q7ZX05 psi-mi:mcm3m_xenla(display_long)|uniprotkb:Maternal minichromosome maintenance protein 3(gene name synonym)|uniprotkb:P1 homolog(gene name synonym)|uniprotkb:p100(gene name synonym)|uniprotkb:XRLF subunit beta(gene name synonym)|uniprotkb:mmcm3(gene name)|psi-mi:mmcm3(display_short) psi-mi:mcm2_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:BM28-homolog(gene name synonym)|uniprotkb:p112(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789478 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001081412.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR018525|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR031327|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|mint:P49739|interpro:IPR041562 go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR027925|refseq:NP_001080759.1|interpro:IPR008045(MCM protein 2)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55861|interpro:IPR041562 - - - figure legend:2C|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:LBdvRzij5a5buPkt/86l4Tl4HcE8355 rogid:BKavzWA0OlaUmzbdJtq74Bk9qKM8355 intact-crc:AF08D2B07C437DEA|rigid:PNX+a1ZYfmgJAZE4pbDgrAo5oCk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49739 uniprotkb:P55862 intact:EBI-491720|uniprotkb:Q2NL58|uniprotkb:Q91919 intact:EBI-876879|uniprotkb:Q5D0A3 psi-mi:mcm3m_xenla(display_long)|uniprotkb:Maternal minichromosome maintenance protein 3(gene name synonym)|uniprotkb:P1 homolog(gene name synonym)|uniprotkb:p100(gene name synonym)|uniprotkb:XRLF subunit beta(gene name synonym)|uniprotkb:mmcm3(gene name)|psi-mi:mmcm3(display_short) psi-mi:mcm5a_xenla(display_long)|uniprotkb:CDC46 homolog A(gene name synonym)|uniprotkb:CDC46p(gene name synonym)|uniprotkb:p92(gene name synonym)|uniprotkb:mcm5-a(gene name)|psi-mi:mcm5-a(display_short)|uniprotkb:cdc46-a(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789478 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001081412.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR018525|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR031327|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|mint:P49739|interpro:IPR041562 go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR027925|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001080893.1|interpro:IPR008048(MCM protein 5)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55862|interpro:IPR041562 - - - figure legend:2C|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:LBdvRzij5a5buPkt/86l4Tl4HcE8355 rogid:2AhC8Mo3s9VuusyTSZ0yryyL0ok8355 intact-crc:AF08D2B07C437DEA|rigid:PNX+a1ZYfmgJAZE4pbDgrAo5oCk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P55861 uniprotkb:P49739 intact:EBI-876864|uniprotkb:O42588|uniprotkb:Q7ZX05 intact:EBI-491720|uniprotkb:Q2NL58|uniprotkb:Q91919 psi-mi:mcm2_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:BM28-homolog(gene name synonym)|uniprotkb:p112(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short) psi-mi:mcm3m_xenla(display_long)|uniprotkb:Maternal minichromosome maintenance protein 3(gene name synonym)|uniprotkb:P1 homolog(gene name synonym)|uniprotkb:p100(gene name synonym)|uniprotkb:XRLF subunit beta(gene name synonym)|uniprotkb:mmcm3(gene name)|psi-mi:mmcm3(display_short) psi-mi:"MI:0027"(cosedimentation) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789491 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR027925|refseq:NP_001080759.1|interpro:IPR008045(MCM protein 2)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55861|interpro:IPR041562 interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001081412.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR018525|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR031327|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|mint:P49739|interpro:IPR041562 - - - figure legend:4|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:BKavzWA0OlaUmzbdJtq74Bk9qKM8355 rogid:LBdvRzij5a5buPkt/86l4Tl4HcE8355 intact-crc:01E974B3EE66A810|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P55861 uniprotkb:Q5XK83 intact:EBI-876864|uniprotkb:O42588|uniprotkb:Q7ZX05 intact:EBI-1789370|uniprotkb:O42589 psi-mi:mcm2_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:BM28-homolog(gene name synonym)|uniprotkb:p112(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short) psi-mi:mcm4a_xenla(display_long)|uniprotkb:mcm4-a(gene name)|psi-mi:mcm4-a(display_short)|uniprotkb:Minichromosome maintenance protein 4-A(gene name synonym)|uniprotkb:CDC21 homolog-A(gene name synonym)|uniprotkb:P1-CDC21-A(gene name synonym)|uniprotkb:p98(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789491 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR027925|refseq:NP_001080759.1|interpro:IPR008045(MCM protein 2)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55861|interpro:IPR041562 interpro:IPR033762|refseq:NP_001079069.1|interpro:IPR008047(MCM protein 4)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027925|interpro:IPR027417|mint:Q5XK83|interpro:IPR041562|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity) - - - figure legend:4|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:BKavzWA0OlaUmzbdJtq74Bk9qKM8355 rogid:VBIiuJghubSRemwMGVBc8alovhI8355 intact-crc:01E974B3EE66A810|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P55861 uniprotkb:P55862 intact:EBI-876864|uniprotkb:O42588|uniprotkb:Q7ZX05 intact:EBI-876879|uniprotkb:Q5D0A3 psi-mi:mcm2_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:BM28-homolog(gene name synonym)|uniprotkb:p112(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short) psi-mi:mcm5a_xenla(display_long)|uniprotkb:CDC46 homolog A(gene name synonym)|uniprotkb:CDC46p(gene name synonym)|uniprotkb:p92(gene name synonym)|uniprotkb:mcm5-a(gene name)|psi-mi:mcm5-a(display_short)|uniprotkb:cdc46-a(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789491 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR027925|refseq:NP_001080759.1|interpro:IPR008045(MCM protein 2)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55861|interpro:IPR041562 go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR027925|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001080893.1|interpro:IPR008048(MCM protein 5)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55862|interpro:IPR041562 - - - figure legend:4|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:BKavzWA0OlaUmzbdJtq74Bk9qKM8355 rogid:2AhC8Mo3s9VuusyTSZ0yryyL0ok8355 intact-crc:01E974B3EE66A810|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P55861 uniprotkb:Q5FWY4 intact:EBI-876864|uniprotkb:O42588|uniprotkb:Q7ZX05 intact:EBI-1789358|uniprotkb:O42590 psi-mi:mcm2_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:BM28-homolog(gene name synonym)|uniprotkb:p112(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short) psi-mi:mcm6m_xenla(display_long)|uniprotkb:mmcm6(gene name)|psi-mi:mmcm6(display_short)|uniprotkb:Maternal minichromosome maintenance protein 6(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789491 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR027925|refseq:NP_001080759.1|interpro:IPR008045(MCM protein 2)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55861|interpro:IPR041562 interpro:IPR033762|refseq:NP_001081822.1|interpro:IPR008049(MCM protein 6)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027925|interpro:IPR027417|interpro:IPR041024|interpro:IPR041562|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity) - - - figure legend:4|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:BKavzWA0OlaUmzbdJtq74Bk9qKM8355 rogid:jlU3T5P3p9NkbPuq7CADRoBDNTc8355 intact-crc:01E974B3EE66A810|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P55861 uniprotkb:Q91876 intact:EBI-876864|uniprotkb:O42588|uniprotkb:Q7ZX05 intact:EBI-876852|uniprotkb:O42591|uniprotkb:Q6GQ16 psi-mi:mcm2_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:BM28-homolog(gene name synonym)|uniprotkb:p112(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short) psi-mi:mcm7a_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 7-A(gene name synonym)|uniprotkb:CDC47 homolog A(gene name synonym)|uniprotkb:CDC47p(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:mcm7-a(gene name)|psi-mi:mcm7-a(display_short)|uniprotkb:cdc47(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789491 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR027925|refseq:NP_001080759.1|interpro:IPR008045(MCM protein 2)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55861|interpro:IPR041562 go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR027925|refseq:NP_001081466.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:Q91876|interpro:IPR041562 - - - figure legend:4|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:BKavzWA0OlaUmzbdJtq74Bk9qKM8355 rogid:IPLvcG4PDdfeYmVQhOOHEVSG1+s8355 intact-crc:01E974B3EE66A810|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P55861 uniprotkb:P49739 intact:EBI-876864|uniprotkb:O42588|uniprotkb:Q7ZX05 intact:EBI-491720|uniprotkb:Q2NL58|uniprotkb:Q91919 psi-mi:mcm2_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:BM28-homolog(gene name synonym)|uniprotkb:p112(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short) psi-mi:mcm3m_xenla(display_long)|uniprotkb:Maternal minichromosome maintenance protein 3(gene name synonym)|uniprotkb:P1 homolog(gene name synonym)|uniprotkb:p100(gene name synonym)|uniprotkb:XRLF subunit beta(gene name synonym)|uniprotkb:mmcm3(gene name)|psi-mi:mmcm3(display_short) psi-mi:"MI:0027"(cosedimentation) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789507 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR027925|refseq:NP_001080759.1|interpro:IPR008045(MCM protein 2)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55861|interpro:IPR041562 interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001081412.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR018525|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR031327|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|mint:P49739|interpro:IPR041562 - - - figure legend:4A. 4B|comment:Similar results were opbserved with purified RLF-M fraction|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:BKavzWA0OlaUmzbdJtq74Bk9qKM8355 rogid:LBdvRzij5a5buPkt/86l4Tl4HcE8355 intact-crc:18067CFFF26E9120|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P55861 uniprotkb:Q5XK83 intact:EBI-876864|uniprotkb:O42588|uniprotkb:Q7ZX05 intact:EBI-1789370|uniprotkb:O42589 psi-mi:mcm2_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:BM28-homolog(gene name synonym)|uniprotkb:p112(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short) psi-mi:mcm4a_xenla(display_long)|uniprotkb:mcm4-a(gene name)|psi-mi:mcm4-a(display_short)|uniprotkb:Minichromosome maintenance protein 4-A(gene name synonym)|uniprotkb:CDC21 homolog-A(gene name synonym)|uniprotkb:P1-CDC21-A(gene name synonym)|uniprotkb:p98(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789507 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR027925|refseq:NP_001080759.1|interpro:IPR008045(MCM protein 2)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55861|interpro:IPR041562 interpro:IPR033762|refseq:NP_001079069.1|interpro:IPR008047(MCM protein 4)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027925|interpro:IPR027417|mint:Q5XK83|interpro:IPR041562|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity) - - - figure legend:4A. 4B|comment:Similar results were opbserved with purified RLF-M fraction|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:BKavzWA0OlaUmzbdJtq74Bk9qKM8355 rogid:VBIiuJghubSRemwMGVBc8alovhI8355 intact-crc:18067CFFF26E9120|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P55861 uniprotkb:P55862 intact:EBI-876864|uniprotkb:O42588|uniprotkb:Q7ZX05 intact:EBI-876879|uniprotkb:Q5D0A3 psi-mi:mcm2_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:BM28-homolog(gene name synonym)|uniprotkb:p112(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short) psi-mi:mcm5a_xenla(display_long)|uniprotkb:CDC46 homolog A(gene name synonym)|uniprotkb:CDC46p(gene name synonym)|uniprotkb:p92(gene name synonym)|uniprotkb:mcm5-a(gene name)|psi-mi:mcm5-a(display_short)|uniprotkb:cdc46-a(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789507 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR027925|refseq:NP_001080759.1|interpro:IPR008045(MCM protein 2)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55861|interpro:IPR041562 go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR027925|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001080893.1|interpro:IPR008048(MCM protein 5)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55862|interpro:IPR041562 - - - figure legend:4A. 4B|comment:Similar results were opbserved with purified RLF-M fraction|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:BKavzWA0OlaUmzbdJtq74Bk9qKM8355 rogid:2AhC8Mo3s9VuusyTSZ0yryyL0ok8355 intact-crc:18067CFFF26E9120|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P55861 uniprotkb:Q5FWY4 intact:EBI-876864|uniprotkb:O42588|uniprotkb:Q7ZX05 intact:EBI-1789358|uniprotkb:O42590 psi-mi:mcm2_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:BM28-homolog(gene name synonym)|uniprotkb:p112(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short) psi-mi:mcm6m_xenla(display_long)|uniprotkb:mmcm6(gene name)|psi-mi:mmcm6(display_short)|uniprotkb:Maternal minichromosome maintenance protein 6(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789507 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR027925|refseq:NP_001080759.1|interpro:IPR008045(MCM protein 2)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55861|interpro:IPR041562 interpro:IPR033762|refseq:NP_001081822.1|interpro:IPR008049(MCM protein 6)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027925|interpro:IPR027417|interpro:IPR041024|interpro:IPR041562|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity) - - - figure legend:4A. 4B|comment:Similar results were opbserved with purified RLF-M fraction|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:BKavzWA0OlaUmzbdJtq74Bk9qKM8355 rogid:jlU3T5P3p9NkbPuq7CADRoBDNTc8355 intact-crc:18067CFFF26E9120|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P55861 uniprotkb:Q91876 intact:EBI-876864|uniprotkb:O42588|uniprotkb:Q7ZX05 intact:EBI-876852|uniprotkb:O42591|uniprotkb:Q6GQ16 psi-mi:mcm2_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:BM28-homolog(gene name synonym)|uniprotkb:p112(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short) psi-mi:mcm7a_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 7-A(gene name synonym)|uniprotkb:CDC47 homolog A(gene name synonym)|uniprotkb:CDC47p(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:mcm7-a(gene name)|psi-mi:mcm7-a(display_short)|uniprotkb:cdc47(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789507 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR027925|refseq:NP_001080759.1|interpro:IPR008045(MCM protein 2)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55861|interpro:IPR041562 go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR027925|refseq:NP_001081466.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:Q91876|interpro:IPR041562 - - - figure legend:4A. 4B|comment:Similar results were opbserved with purified RLF-M fraction|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:BKavzWA0OlaUmzbdJtq74Bk9qKM8355 rogid:IPLvcG4PDdfeYmVQhOOHEVSG1+s8355 intact-crc:18067CFFF26E9120|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49739 uniprotkb:P55861 intact:EBI-491720|uniprotkb:Q2NL58|uniprotkb:Q91919 intact:EBI-876864|uniprotkb:O42588|uniprotkb:Q7ZX05 psi-mi:mcm3m_xenla(display_long)|uniprotkb:Maternal minichromosome maintenance protein 3(gene name synonym)|uniprotkb:P1 homolog(gene name synonym)|uniprotkb:p100(gene name synonym)|uniprotkb:XRLF subunit beta(gene name synonym)|uniprotkb:mmcm3(gene name)|psi-mi:mmcm3(display_short) psi-mi:mcm2_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:BM28-homolog(gene name synonym)|uniprotkb:p112(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short) psi-mi:"MI:0027"(cosedimentation) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789521 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001081412.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR018525|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR031327|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|mint:P49739|interpro:IPR041562 go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR027925|refseq:NP_001080759.1|interpro:IPR008045(MCM protein 2)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55861|interpro:IPR041562 - - - figure legend:4A, 4B|comment:Similar results were opbserved with purified RLF-M fraction|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:LBdvRzij5a5buPkt/86l4Tl4HcE8355 rogid:BKavzWA0OlaUmzbdJtq74Bk9qKM8355 intact-crc:10E2D470CC978B46|rigid:/iuqj8dAxAtz2hulu3/gWzNrFvg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P55861 uniprotkb:P49739 intact:EBI-876864|uniprotkb:O42588|uniprotkb:Q7ZX05 intact:EBI-491720|uniprotkb:Q2NL58|uniprotkb:Q91919 psi-mi:mcm2_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:BM28-homolog(gene name synonym)|uniprotkb:p112(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short) psi-mi:mcm3m_xenla(display_long)|uniprotkb:Maternal minichromosome maintenance protein 3(gene name synonym)|uniprotkb:P1 homolog(gene name synonym)|uniprotkb:p100(gene name synonym)|uniprotkb:XRLF subunit beta(gene name synonym)|uniprotkb:mmcm3(gene name)|psi-mi:mmcm3(display_short) psi-mi:"MI:0091"(chromatography technology) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789534 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR027925|refseq:NP_001080759.1|interpro:IPR008045(MCM protein 2)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55861|interpro:IPR041562 interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001081412.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR018525|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR031327|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|mint:P49739|interpro:IPR041562 - - - figure legend:5|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:BKavzWA0OlaUmzbdJtq74Bk9qKM8355 rogid:LBdvRzij5a5buPkt/86l4Tl4HcE8355 intact-crc:33B3D10A4B0EC382|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P55861 uniprotkb:Q5XK83 intact:EBI-876864|uniprotkb:O42588|uniprotkb:Q7ZX05 intact:EBI-1789370|uniprotkb:O42589 psi-mi:mcm2_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:BM28-homolog(gene name synonym)|uniprotkb:p112(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short) psi-mi:mcm4a_xenla(display_long)|uniprotkb:mcm4-a(gene name)|psi-mi:mcm4-a(display_short)|uniprotkb:Minichromosome maintenance protein 4-A(gene name synonym)|uniprotkb:CDC21 homolog-A(gene name synonym)|uniprotkb:P1-CDC21-A(gene name synonym)|uniprotkb:p98(gene name synonym) psi-mi:"MI:0091"(chromatography technology) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789534 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR027925|refseq:NP_001080759.1|interpro:IPR008045(MCM protein 2)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55861|interpro:IPR041562 interpro:IPR033762|refseq:NP_001079069.1|interpro:IPR008047(MCM protein 4)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027925|interpro:IPR027417|mint:Q5XK83|interpro:IPR041562|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity) - - - figure legend:5|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:BKavzWA0OlaUmzbdJtq74Bk9qKM8355 rogid:VBIiuJghubSRemwMGVBc8alovhI8355 intact-crc:33B3D10A4B0EC382|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P55861 uniprotkb:P55862 intact:EBI-876864|uniprotkb:O42588|uniprotkb:Q7ZX05 intact:EBI-876879|uniprotkb:Q5D0A3 psi-mi:mcm2_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:BM28-homolog(gene name synonym)|uniprotkb:p112(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short) psi-mi:mcm5a_xenla(display_long)|uniprotkb:CDC46 homolog A(gene name synonym)|uniprotkb:CDC46p(gene name synonym)|uniprotkb:p92(gene name synonym)|uniprotkb:mcm5-a(gene name)|psi-mi:mcm5-a(display_short)|uniprotkb:cdc46-a(gene name synonym) psi-mi:"MI:0091"(chromatography technology) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789534 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR027925|refseq:NP_001080759.1|interpro:IPR008045(MCM protein 2)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55861|interpro:IPR041562 go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR027925|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001080893.1|interpro:IPR008048(MCM protein 5)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55862|interpro:IPR041562 - - - figure legend:5|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:BKavzWA0OlaUmzbdJtq74Bk9qKM8355 rogid:2AhC8Mo3s9VuusyTSZ0yryyL0ok8355 intact-crc:33B3D10A4B0EC382|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P55861 uniprotkb:Q5FWY4 intact:EBI-876864|uniprotkb:O42588|uniprotkb:Q7ZX05 intact:EBI-1789358|uniprotkb:O42590 psi-mi:mcm2_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:BM28-homolog(gene name synonym)|uniprotkb:p112(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short) psi-mi:mcm6m_xenla(display_long)|uniprotkb:mmcm6(gene name)|psi-mi:mmcm6(display_short)|uniprotkb:Maternal minichromosome maintenance protein 6(gene name synonym) psi-mi:"MI:0091"(chromatography technology) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789534 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR027925|refseq:NP_001080759.1|interpro:IPR008045(MCM protein 2)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55861|interpro:IPR041562 interpro:IPR033762|refseq:NP_001081822.1|interpro:IPR008049(MCM protein 6)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027925|interpro:IPR027417|interpro:IPR041024|interpro:IPR041562|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity) - - - figure legend:5|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:BKavzWA0OlaUmzbdJtq74Bk9qKM8355 rogid:jlU3T5P3p9NkbPuq7CADRoBDNTc8355 intact-crc:33B3D10A4B0EC382|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P55861 uniprotkb:Q91876 intact:EBI-876864|uniprotkb:O42588|uniprotkb:Q7ZX05 intact:EBI-876852|uniprotkb:O42591|uniprotkb:Q6GQ16 psi-mi:mcm2_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:BM28-homolog(gene name synonym)|uniprotkb:p112(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short) psi-mi:mcm7a_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 7-A(gene name synonym)|uniprotkb:CDC47 homolog A(gene name synonym)|uniprotkb:CDC47p(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:mcm7-a(gene name)|psi-mi:mcm7-a(display_short)|uniprotkb:cdc47(gene name synonym) psi-mi:"MI:0091"(chromatography technology) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789534 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR027925|refseq:NP_001080759.1|interpro:IPR008045(MCM protein 2)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55861|interpro:IPR041562 go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR027925|refseq:NP_001081466.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:Q91876|interpro:IPR041562 - - - figure legend:5|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:BKavzWA0OlaUmzbdJtq74Bk9qKM8355 rogid:IPLvcG4PDdfeYmVQhOOHEVSG1+s8355 intact-crc:33B3D10A4B0EC382|rigid:v2WquJGRKy8qgPQT4XUcEXf+12A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49739 uniprotkb:P55862 intact:EBI-491720|uniprotkb:Q2NL58|uniprotkb:Q91919 intact:EBI-876879|uniprotkb:Q5D0A3 psi-mi:mcm3m_xenla(display_long)|uniprotkb:Maternal minichromosome maintenance protein 3(gene name synonym)|uniprotkb:P1 homolog(gene name synonym)|uniprotkb:p100(gene name synonym)|uniprotkb:XRLF subunit beta(gene name synonym)|uniprotkb:mmcm3(gene name)|psi-mi:mmcm3(display_short) psi-mi:mcm5a_xenla(display_long)|uniprotkb:CDC46 homolog A(gene name synonym)|uniprotkb:CDC46p(gene name synonym)|uniprotkb:p92(gene name synonym)|uniprotkb:mcm5-a(gene name)|psi-mi:mcm5-a(display_short)|uniprotkb:cdc46-a(gene name synonym) psi-mi:"MI:0091"(chromatography technology) Thommes et al. (1997) pubmed:9214646 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1789543 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001081412.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR018525|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR031327|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|mint:P49739|interpro:IPR041562 go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR027925|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001080893.1|interpro:IPR008048(MCM protein 5)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55862|interpro:IPR041562 - - - figure legend:5|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2008/07/08 2014/10/16 rogid:LBdvRzij5a5buPkt/86l4Tl4HcE8355 rogid:2AhC8Mo3s9VuusyTSZ0yryyL0ok8355 intact-crc:C6A446A4D964264D|rigid:q1wy78tmA2Ti9pgFuqXWXhH4s0Y false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)