#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P09884 uniprotkb:P03070 intact:EBI-850026|uniprotkb:Q86UQ7|intact:EBI-28966824|ensembl:ENSP00000368349 intact:EBI-617698 psi-mi:dpola_human(display_long)|uniprotkb:POLA1(gene name)|psi-mi:POLA1(display_short)|uniprotkb:POLA(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym) psi-mi:lt_sv40(display_long) psi-mi:"MI:0019"(coimmunoprecipitation) Dornreiter et al. (1993) mint:MINT-6549563|pubmed:8380896 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:1891767(sv40)|taxid:1891767(sv40) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8655454|mint:MINT-6627953 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000368349|refseq:NP_058633.2|ensembl:ENSG00000101868(gene)|ensembl:ENST00000379059(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|mint:P09884|rcsb pdb:1K0P|rcsb pdb:1K18|rcsb pdb:1N5G|rcsb pdb:4Q5V|rcsb pdb:4QCL|rcsb pdb:4Y97|rcsb pdb:5EXR|rcsb pdb:5IUD|rcsb pdb:6AS7|reactome:R-HSA-113501|reactome:R-HSA-174411|reactome:R-HSA-174430|reactome:R-HSA-68952|reactome:R-HSA-68962|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-9710421|mint:MINT-6627956(identity)|uniprotkb:P09884(P09884) go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0016787"(hydrolase activity)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039576"(suppression by virus of host JAK-STAT cascade via inhibition of JAK1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039686"(bidirectional double-stranded viral DNA replication)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR003133(T antigen, Ori-binding)|interpro:IPR010932(Large T antigen, polyomavirus, C-terminus)|interpro:IPR016392(Large T antigen, polyomaviridae)|interpro:IPR017910|interpro:IPR027417|interpro:IPR036869|rcsb pdb:1EJL|rcsb pdb:1GH6|rcsb pdb:1N25|rcsb pdb:1Q1S|rcsb pdb:1Q1T|rcsb pdb:1SVL|rcsb pdb:1SVM|rcsb pdb:1SVO|rcsb pdb:1TBD|rcsb pdb:1Z1D|rcsb pdb:2FUF|rcsb pdb:2H1L|rcsb pdb:2IF9|rcsb pdb:2IPR|rcsb pdb:2ITJ|rcsb pdb:2ITL|rcsb pdb:2NL8|rcsb pdb:2NTC|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|rcsb pdb:2TBD|rcsb pdb:3QK2|rcsb pdb:3QN2|rcsb pdb:4E2I|rcsb pdb:4FGN|rcsb pdb:4GDF|rcsb pdb:4RXH|rcsb pdb:5D9I|refseq:YP_003708382.1|mint:P03070|dip:DIP-24251N|mint:MINT-6627954(identity)|uniprotkb:P03070(P03070) - - - figure legend:F1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation taxid:-3(unknown)|taxid:-3(Unknown) - 2008/06/26 2019/10/18 rogid:X/oe9TEoaNUf5UPtWEXunsFtRZg9606 rogid:IMcAp2PRxZXkbJ1eiXhJU9rD2JM1891767 intact-crc:A7AFA5113A7A56C2|rigid:8ZHdfkUJIbCNneE7GfQqws7NXQk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03070 uniprotkb:P09884 intact:EBI-617698 intact:EBI-850026|uniprotkb:Q86UQ7|intact:EBI-28966824|ensembl:ENSP00000368349 psi-mi:lt_sv40(display_long) psi-mi:dpola_human(display_long)|uniprotkb:POLA1(gene name)|psi-mi:POLA1(display_short)|uniprotkb:POLA(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Dornreiter et al. (1993) mint:MINT-6549563|pubmed:8380896 taxid:1891767(sv40)|taxid:1891767(sv40) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8655467|mint:MINT-6627958 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0016787"(hydrolase activity)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039576"(suppression by virus of host JAK-STAT cascade via inhibition of JAK1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039686"(bidirectional double-stranded viral DNA replication)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR003133(T antigen, Ori-binding)|interpro:IPR010932(Large T antigen, polyomavirus, C-terminus)|interpro:IPR016392(Large T antigen, polyomaviridae)|interpro:IPR017910|interpro:IPR027417|interpro:IPR036869|rcsb pdb:1EJL|rcsb pdb:1GH6|rcsb pdb:1N25|rcsb pdb:1Q1S|rcsb pdb:1Q1T|rcsb pdb:1SVL|rcsb pdb:1SVM|rcsb pdb:1SVO|rcsb pdb:1TBD|rcsb pdb:1Z1D|rcsb pdb:2FUF|rcsb pdb:2H1L|rcsb pdb:2IF9|rcsb pdb:2IPR|rcsb pdb:2ITJ|rcsb pdb:2ITL|rcsb pdb:2NL8|rcsb pdb:2NTC|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|rcsb pdb:2TBD|rcsb pdb:3QK2|rcsb pdb:3QN2|rcsb pdb:4E2I|rcsb pdb:4FGN|rcsb pdb:4GDF|rcsb pdb:4RXH|rcsb pdb:5D9I|refseq:YP_003708382.1|mint:P03070|dip:DIP-24251N|mint:MINT-6627959(identity)|uniprotkb:P03070(P03070) ensembl:ENSP00000368349|refseq:NP_058633.2|ensembl:ENSG00000101868(gene)|ensembl:ENST00000379059(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|mint:P09884|rcsb pdb:1K0P|rcsb pdb:1K18|rcsb pdb:1N5G|rcsb pdb:4Q5V|rcsb pdb:4QCL|rcsb pdb:4Y97|rcsb pdb:5EXR|rcsb pdb:5IUD|rcsb pdb:6AS7|reactome:R-HSA-113501|reactome:R-HSA-174411|reactome:R-HSA-174430|reactome:R-HSA-68952|reactome:R-HSA-68962|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-9710421|mint:MINT-6627961(identity)|uniprotkb:P09884(P09884) - - - figure legend:F1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation taxid:-3(unknown)|taxid:-3(Unknown) - 2008/06/26 2019/10/18 rogid:IMcAp2PRxZXkbJ1eiXhJU9rD2JM1891767 rogid:X/oe9TEoaNUf5UPtWEXunsFtRZg9606 intact-crc:00D33B835DF37B51|rigid:8ZHdfkUJIbCNneE7GfQqws7NXQk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03070 uniprotkb:P09884 intact:EBI-617698 intact:EBI-850026|uniprotkb:Q86UQ7|intact:EBI-28966824|ensembl:ENSP00000368349 psi-mi:lt_sv40(display_long) psi-mi:dpola_human(display_long)|uniprotkb:POLA1(gene name)|psi-mi:POLA1(display_short)|uniprotkb:POLA(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym) psi-mi:"MI:0096"(pull down) Dornreiter et al. (1993) mint:MINT-6549563|pubmed:8380896 taxid:1891767(sv40)|taxid:1891767(sv40) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8655490|mint:MINT-6627965 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0016787"(hydrolase activity)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039576"(suppression by virus of host JAK-STAT cascade via inhibition of JAK1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039686"(bidirectional double-stranded viral DNA replication)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR003133(T antigen, Ori-binding)|interpro:IPR010932(Large T antigen, polyomavirus, C-terminus)|interpro:IPR016392(Large T antigen, polyomaviridae)|interpro:IPR017910|interpro:IPR027417|interpro:IPR036869|rcsb pdb:1EJL|rcsb pdb:1GH6|rcsb pdb:1N25|rcsb pdb:1Q1S|rcsb pdb:1Q1T|rcsb pdb:1SVL|rcsb pdb:1SVM|rcsb pdb:1SVO|rcsb pdb:1TBD|rcsb pdb:1Z1D|rcsb pdb:2FUF|rcsb pdb:2H1L|rcsb pdb:2IF9|rcsb pdb:2IPR|rcsb pdb:2ITJ|rcsb pdb:2ITL|rcsb pdb:2NL8|rcsb pdb:2NTC|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|rcsb pdb:2TBD|rcsb pdb:3QK2|rcsb pdb:3QN2|rcsb pdb:4E2I|rcsb pdb:4FGN|rcsb pdb:4GDF|rcsb pdb:4RXH|rcsb pdb:5D9I|refseq:YP_003708382.1|mint:P03070|dip:DIP-24251N|mint:MINT-6627966(identity)|uniprotkb:P03070(P03070) ensembl:ENSP00000368349|refseq:NP_058633.2|ensembl:ENSG00000101868(gene)|ensembl:ENST00000379059(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|mint:P09884|rcsb pdb:1K0P|rcsb pdb:1K18|rcsb pdb:1N5G|rcsb pdb:4Q5V|rcsb pdb:4QCL|rcsb pdb:4Y97|rcsb pdb:5EXR|rcsb pdb:5IUD|rcsb pdb:6AS7|reactome:R-HSA-113501|reactome:R-HSA-174411|reactome:R-HSA-174430|reactome:R-HSA-68952|reactome:R-HSA-68962|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-9710421|mint:MINT-6627968(identity)|uniprotkb:P09884(P09884) - - - figure legend:F2|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation taxid:-3(unknown)|taxid:-3(Unknown) - 2008/06/26 2019/10/18 rogid:IMcAp2PRxZXkbJ1eiXhJU9rD2JM1891767 rogid:X/oe9TEoaNUf5UPtWEXunsFtRZg9606 intact-crc:160319FE94F80F92|rigid:8ZHdfkUJIbCNneE7GfQqws7NXQk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09884 uniprotkb:P03070 intact:EBI-850026|uniprotkb:Q86UQ7|intact:EBI-28966824|ensembl:ENSP00000368349 intact:EBI-617698 psi-mi:dpola_human(display_long)|uniprotkb:POLA1(gene name)|psi-mi:POLA1(display_short)|uniprotkb:POLA(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym) psi-mi:lt_sv40(display_long) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Dornreiter et al. (1993) mint:MINT-6549563|pubmed:8380896 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:1891767(sv40)|taxid:1891767(sv40) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-8655513|mint:MINT-6627972 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000368349|refseq:NP_058633.2|ensembl:ENSG00000101868(gene)|ensembl:ENST00000379059(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|mint:P09884|rcsb pdb:1K0P|rcsb pdb:1K18|rcsb pdb:1N5G|rcsb pdb:4Q5V|rcsb pdb:4QCL|rcsb pdb:4Y97|rcsb pdb:5EXR|rcsb pdb:5IUD|rcsb pdb:6AS7|reactome:R-HSA-113501|reactome:R-HSA-174411|reactome:R-HSA-174430|reactome:R-HSA-68952|reactome:R-HSA-68962|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-9710421|mint:MINT-6627975(identity)|uniprotkb:P09884(P09884) go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0016787"(hydrolase activity)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039576"(suppression by virus of host JAK-STAT cascade via inhibition of JAK1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039686"(bidirectional double-stranded viral DNA replication)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR003133(T antigen, Ori-binding)|interpro:IPR010932(Large T antigen, polyomavirus, C-terminus)|interpro:IPR016392(Large T antigen, polyomaviridae)|interpro:IPR017910|interpro:IPR027417|interpro:IPR036869|rcsb pdb:1EJL|rcsb pdb:1GH6|rcsb pdb:1N25|rcsb pdb:1Q1S|rcsb pdb:1Q1T|rcsb pdb:1SVL|rcsb pdb:1SVM|rcsb pdb:1SVO|rcsb pdb:1TBD|rcsb pdb:1Z1D|rcsb pdb:2FUF|rcsb pdb:2H1L|rcsb pdb:2IF9|rcsb pdb:2IPR|rcsb pdb:2ITJ|rcsb pdb:2ITL|rcsb pdb:2NL8|rcsb pdb:2NTC|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|rcsb pdb:2TBD|rcsb pdb:3QK2|rcsb pdb:3QN2|rcsb pdb:4E2I|rcsb pdb:4FGN|rcsb pdb:4GDF|rcsb pdb:4RXH|rcsb pdb:5D9I|refseq:YP_003708382.1|mint:P03070|dip:DIP-24251N|mint:MINT-6627973(identity)|uniprotkb:P03070(P03070) - - - figure legend:F3 F5|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation taxid:-3(unknown)|taxid:-3(Unknown) - 2008/06/26 2019/10/18 rogid:X/oe9TEoaNUf5UPtWEXunsFtRZg9606 rogid:IMcAp2PRxZXkbJ1eiXhJU9rD2JM1891767 intact-crc:8659B0BFFDD03828|rigid:8ZHdfkUJIbCNneE7GfQqws7NXQk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)