#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P10193	uniprotkb:P09884	intact:EBI-8596799|uniprotkb:B9VQD6|intact:MINT-191327|uniprotkb:Q09IC4	intact:EBI-850026|uniprotkb:Q86UQ7|intact:EBI-28966824|ensembl:ENSP00000368349	psi-mi:obp_hhv11(display_long)|uniprotkb:UL9(orf name)|uniprotkb:OriBP(gene name synonym)	psi-mi:dpola_human(display_long)|uniprotkb:POLA1(gene name)|psi-mi:POLA1(display_short)|uniprotkb:POLA(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Lee et al. (1995)	mint:MINT-6666760|pubmed:7644508|doi:10.1073/pnas.92.17.7882	taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8596818|mint:MINT-6733051	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0039686"(bidirectional double-stranded viral DNA replication)|go:"GO:0042025"(host cell nucleus)|interpro:IPR003450(Origin of replication binding protein)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|mint:P10193|dip:DIP-1095N|mint:MINT-6733055(identity)|uniprotkb:P10193(P10193)	ensembl:ENSP00000368349|refseq:NP_058633.2|ensembl:ENSG00000101868(gene)|ensembl:ENST00000379059(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|mint:P09884|rcsb pdb:1K0P|rcsb pdb:1K18|rcsb pdb:1N5G|rcsb pdb:4Q5V|rcsb pdb:4QCL|rcsb pdb:4Y97|rcsb pdb:5EXR|rcsb pdb:5IUD|rcsb pdb:6AS7|reactome:R-HSA-113501|reactome:R-HSA-174411|reactome:R-HSA-174430|reactome:R-HSA-68952|reactome:R-HSA-68962|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-9710421|mint:MINT-6733052(identity)|uniprotkb:P09884(P09884)	-	comment:mint|function:"Probably involved in DNA replication. Binds the origin of replication (ori)"	-	figure legend:F1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation	taxid:-3(unknown)|taxid:-3(Unknown)	-	2008/07/25	2014/10/16	rogid:ckRglhldL8cAdJt0odhXbHI+KK010299	rogid:X/oe9TEoaNUf5UPtWEXunsFtRZg9606	intact-crc:D19D61F8B082ACB4|rigid:6xsjSIPlGOvDCKLsjATqNer1/tU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10193	uniprotkb:P09884	intact:EBI-8596799|uniprotkb:B9VQD6|intact:MINT-191327|uniprotkb:Q09IC4	intact:EBI-850026|uniprotkb:Q86UQ7|intact:EBI-28966824|ensembl:ENSP00000368349	psi-mi:obp_hhv11(display_long)|uniprotkb:UL9(orf name)|uniprotkb:OriBP(gene name synonym)	psi-mi:dpola_human(display_long)|uniprotkb:POLA1(gene name)|psi-mi:POLA1(display_short)|uniprotkb:POLA(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Lee et al. (1995)	mint:MINT-6666760|pubmed:7644508|doi:10.1073/pnas.92.17.7882	taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8596850|mint:MINT-6733058	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0039686"(bidirectional double-stranded viral DNA replication)|go:"GO:0042025"(host cell nucleus)|interpro:IPR003450(Origin of replication binding protein)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|mint:P10193|dip:DIP-1095N|mint:MINT-6733062(identity)|uniprotkb:P10193(P10193)	ensembl:ENSP00000368349|refseq:NP_058633.2|ensembl:ENSG00000101868(gene)|ensembl:ENST00000379059(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|mint:P09884|rcsb pdb:1K0P|rcsb pdb:1K18|rcsb pdb:1N5G|rcsb pdb:4Q5V|rcsb pdb:4QCL|rcsb pdb:4Y97|rcsb pdb:5EXR|rcsb pdb:5IUD|rcsb pdb:6AS7|reactome:R-HSA-113501|reactome:R-HSA-174411|reactome:R-HSA-174430|reactome:R-HSA-68952|reactome:R-HSA-68962|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-9710421|mint:MINT-6733059(identity)|uniprotkb:P09884(P09884)	-	comment:mint|function:"Probably involved in DNA replication. Binds the origin of replication (ori)"	-	figure legend:F2|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation	taxid:-3(unknown)|taxid:-3(Unknown)	-	2008/07/25	2014/10/16	rogid:ckRglhldL8cAdJt0odhXbHI+KK010299	rogid:X/oe9TEoaNUf5UPtWEXunsFtRZg9606	intact-crc:BC1D8B91F6B782ED|rigid:6xsjSIPlGOvDCKLsjATqNer1/tU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10193	uniprotkb:P09884	intact:EBI-8596799|uniprotkb:B9VQD6|intact:MINT-191327|uniprotkb:Q09IC4	intact:EBI-850026|uniprotkb:Q86UQ7|intact:EBI-28966824|ensembl:ENSP00000368349	psi-mi:obp_hhv11(display_long)|uniprotkb:UL9(orf name)|uniprotkb:OriBP(gene name synonym)	psi-mi:dpola_human(display_long)|uniprotkb:POLA1(gene name)|psi-mi:POLA1(display_short)|uniprotkb:POLA(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Lee et al. (1995)	mint:MINT-6666760|pubmed:7644508|doi:10.1073/pnas.92.17.7882	taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0471"(MINT)	intact:EBI-8596907|mint:MINT-6733067	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0039686"(bidirectional double-stranded viral DNA replication)|go:"GO:0042025"(host cell nucleus)|interpro:IPR003450(Origin of replication binding protein)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|mint:P10193|dip:DIP-1095N|mint:MINT-6733071(identity)|uniprotkb:P10193(P10193)	ensembl:ENSP00000368349|refseq:NP_058633.2|ensembl:ENSG00000101868(gene)|ensembl:ENST00000379059(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|mint:P09884|rcsb pdb:1K0P|rcsb pdb:1K18|rcsb pdb:1N5G|rcsb pdb:4Q5V|rcsb pdb:4QCL|rcsb pdb:4Y97|rcsb pdb:5EXR|rcsb pdb:5IUD|rcsb pdb:6AS7|reactome:R-HSA-113501|reactome:R-HSA-174411|reactome:R-HSA-174430|reactome:R-HSA-68952|reactome:R-HSA-68962|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-9710421|mint:MINT-6733068(identity)|uniprotkb:P09884(P09884)	-	comment:mint|function:"Probably involved in DNA replication. Binds the origin of replication (ori)"	-	figure legend:F3|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation	taxid:-3(unknown)|taxid:-3(Unknown)	-	2008/07/25	2014/10/16	rogid:ckRglhldL8cAdJt0odhXbHI+KK010299	rogid:X/oe9TEoaNUf5UPtWEXunsFtRZg9606	intact-crc:1B202F330EC40F5E|rigid:6xsjSIPlGOvDCKLsjATqNer1/tU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10193	uniprotkb:P09884	intact:EBI-8596799|uniprotkb:B9VQD6|intact:MINT-191327|uniprotkb:Q09IC4	intact:EBI-850026|uniprotkb:Q86UQ7|intact:EBI-28966824|ensembl:ENSP00000368349	psi-mi:obp_hhv11(display_long)|uniprotkb:UL9(orf name)|uniprotkb:OriBP(gene name synonym)	psi-mi:dpola_human(display_long)|uniprotkb:POLA1(gene name)|psi-mi:POLA1(display_short)|uniprotkb:POLA(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Lee et al. (1995)	mint:MINT-6666760|pubmed:7644508|doi:10.1073/pnas.92.17.7882	taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8596930|mint:MINT-6733076	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0039686"(bidirectional double-stranded viral DNA replication)|go:"GO:0042025"(host cell nucleus)|interpro:IPR003450(Origin of replication binding protein)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|mint:P10193|dip:DIP-1095N|mint:MINT-6733077(identity)|uniprotkb:P10193(P10193)	ensembl:ENSP00000368349|refseq:NP_058633.2|ensembl:ENSG00000101868(gene)|ensembl:ENST00000379059(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|mint:P09884|rcsb pdb:1K0P|rcsb pdb:1K18|rcsb pdb:1N5G|rcsb pdb:4Q5V|rcsb pdb:4QCL|rcsb pdb:4Y97|rcsb pdb:5EXR|rcsb pdb:5IUD|rcsb pdb:6AS7|reactome:R-HSA-113501|reactome:R-HSA-174411|reactome:R-HSA-174430|reactome:R-HSA-68952|reactome:R-HSA-68962|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-9710421|mint:MINT-6733080(identity)|uniprotkb:P09884(P09884)	-	comment:mint|function:"Probably involved in DNA replication. Binds the origin of replication (ori)"	-	figure legend:F4|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation	taxid:-3(unknown)|taxid:-3(Unknown)	-	2008/07/25	2014/10/16	rogid:ckRglhldL8cAdJt0odhXbHI+KK010299	rogid:X/oe9TEoaNUf5UPtWEXunsFtRZg9606	intact-crc:8303C62922897845|rigid:6xsjSIPlGOvDCKLsjATqNer1/tU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)