#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9Y570	uniprotkb:P30153	intact:EBI-1772895|uniprotkb:Q8WYG8|uniprotkb:Q9NVT5|uniprotkb:Q9UI18|uniprotkb:B3KMU6|uniprotkb:B5MEE7|uniprotkb:J3QT22|ensembl:ENSP00000329867	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	psi-mi:ppme1_human(display_long)|uniprotkb:PPME1(gene name)|psi-mi:PPME1(display_short)|uniprotkb:PME1(gene name synonym)|uniprotkb:PP2593(orf name)|uniprotkb:PRO0750(orf name)	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1772928|imex:IM-9155-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057231.1|refseq:NP_001258522.1|ensembl:ENSG00000214517(gene)|ensembl:ENST00000328257(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006482"(protein demethylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051722"(protein C-terminal methylesterase activity)|go:"GO:0051723"(protein methylesterase activity)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR016812(Protein phosphatase methylesterase, eukaryotic)|interpro:IPR029058|rcsb pdb:3C5V|rcsb pdb:3C5W|reactome:R-HSA-69273	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:ZOIwpvvy8nrnGzuNkEu7AZn0JuA9606	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	intact-crc:ABB07665EFBD1014|rigid:V+XfhG2FTk+NPTBu7Gg1SiHNwFE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y570	uniprotkb:P67775	intact:EBI-1772895|uniprotkb:Q8WYG8|uniprotkb:Q9NVT5|uniprotkb:Q9UI18|uniprotkb:B3KMU6|uniprotkb:B5MEE7|uniprotkb:J3QT22|ensembl:ENSP00000329867	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	psi-mi:ppme1_human(display_long)|uniprotkb:PPME1(gene name)|psi-mi:PPME1(display_short)|uniprotkb:PME1(gene name synonym)|uniprotkb:PP2593(orf name)|uniprotkb:PRO0750(orf name)	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1772928|imex:IM-9155-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057231.1|refseq:NP_001258522.1|ensembl:ENSG00000214517(gene)|ensembl:ENST00000328257(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006482"(protein demethylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051722"(protein C-terminal methylesterase activity)|go:"GO:0051723"(protein methylesterase activity)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR016812(Protein phosphatase methylesterase, eukaryotic)|interpro:IPR029058|rcsb pdb:3C5V|rcsb pdb:3C5W|reactome:R-HSA-69273	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:ZOIwpvvy8nrnGzuNkEu7AZn0JuA9606	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	intact-crc:ABB07665EFBD1014|rigid:V+XfhG2FTk+NPTBu7Gg1SiHNwFE	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:Q5FBB7-6	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-989114|ensembl:ENSP00000410458	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:q5fbb7-6(display_long)|uniprotkb:SGO1(gene name)|psi-mi:SGO1(display_short)|uniprotkb:SGOL1(gene name synonym)|uniprotkb:Serologically defined breast cancer antigen NY-BR-85(gene name synonym)|uniprotkb:Shugoshin-like 1(gene name synonym)|uniprotkb:1AB(isoform synonym)|uniprotkb:SgoL1-A1(isoform synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	intact:EBI-989069(sgol1_human)|ensembl:ENSG00000129810(gene)|ensembl:ENST00000412997(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:eGoNXNboUZb0xzdLaTgPrujYwkU9606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:P49368	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:P48643	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:Q99832	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:P78371	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:Q9Y3A3	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:Q9Y570	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-1772895|uniprotkb:Q8WYG8|uniprotkb:Q9NVT5|uniprotkb:Q9UI18|uniprotkb:B3KMU6|uniprotkb:B5MEE7|uniprotkb:J3QT22|ensembl:ENSP00000329867	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:ppme1_human(display_long)|uniprotkb:PPME1(gene name)|psi-mi:PPME1(display_short)|uniprotkb:PME1(gene name synonym)|uniprotkb:PP2593(orf name)|uniprotkb:PRO0750(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	refseq:NP_057231.1|refseq:NP_001258522.1|ensembl:ENSG00000214517(gene)|ensembl:ENST00000328257(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006482"(protein demethylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051722"(protein C-terminal methylesterase activity)|go:"GO:0051723"(protein methylesterase activity)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR016812(Protein phosphatase methylesterase, eukaryotic)|interpro:IPR029058|rcsb pdb:3C5V|rcsb pdb:3C5W|reactome:R-HSA-69273	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:ZOIwpvvy8nrnGzuNkEu7AZn0JuA9606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:P40227	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:P50991	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:Q14BN4-4	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-1517338	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:q14bn4-4(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	intact:EBI-1043216(isoform-parent)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:Pqv5PmRvR/qi8XfY4gDy5MVtGJI9606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:Q86XL3-2	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-1773634	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:q86xl3-2(display_long)|uniprotkb:ANKLE2(gene name)|psi-mi:ANKLE2(display_short)|uniprotkb:KIAA0692(gene name synonym)|uniprotkb:LEM domain-containing protein 4(gene name synonym)|uniprotkb:LEM4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	intact:EBI-1773621(isoform-parent)	psi-mi:"MI:0469"(intact)	-	isoform-comment:No experimental confirmation available.	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:eRtFUd6vfg1I3BLaP6ExtSScac09606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:P30154	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:Q5THK1	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-1773550|uniprotkb:Q5THK4|uniprotkb:Q6ZNN1|uniprotkb:Q6ZWH0|uniprotkb:Q8IW74|uniprotkb:Q9H5T4|ensembl:ENSP00000331845	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:pr14l_human(display_long)|uniprotkb:PRR14L(gene name)|psi-mi:PRR14L(display_short)|uniprotkb:C22orf30(gene name synonym)|uniprotkb:Proline rich 14-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	refseq:XP_011528382.1|refseq:XP_011528383.1|refseq:NP_775837.2|refseq:XP_006724282.1|refseq:XP_006724283.1|ensembl:ENSP00000331845|refseq:XP_016884225.1|refseq:XP_016884226.1|ensembl:ENSG00000183530(gene)|ensembl:ENST00000327423(transcript)|interpro:IPR026320|interpro:IPR028149	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:JPwD2Kz4L2brrLfT41iriYT2Pos9606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:Q5VSL9	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:P78318	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-1055954|uniprotkb:Q8TAB2|ensembl:ENSP00000348784|ensembl:ENSP00000363661	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:igbp1_human(display_long)|uniprotkb:IGBP1(gene name)|psi-mi:IGBP1(display_short)|uniprotkb:IBP1(gene name synonym)|uniprotkb:CD79a-binding protein 1(gene name synonym)|uniprotkb:B-cell signal transduction molecule alpha 4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-16(gene name synonym)|uniprotkb:Protein phosphatase 2/4/6 regulatory subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	refseq:NP_001542.1|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511|mint:P78318|rcsb pdb:4IYP|ensembl:ENSG00000089289(gene)|ensembl:ENST00000342206(transcript)|ensembl:ENST00000356413(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042113"(B cell activation)|refseq:XP_016884978.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:N8w92upYivqH3rjdqNbAcIjDu7I9606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:P17987	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:Q14738	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-396563|uniprotkb:O00494|uniprotkb:O00696|uniprotkb:Q15171|uniprotkb:Q5TC39|uniprotkb:B5BUA6|uniprotkb:A8K3I9|ensembl:ENSP00000417963	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:2a5d_human(display_long)|uniprotkb:PPP2R5D(gene name)|psi-mi:PPP2R5D(display_short)|uniprotkb:PP2A B subunit isoform B'-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-delta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	refseq:NP_006236.1|refseq:NP_851307.1|refseq:NP_851308.1|ensembl:ENSG00000112640(gene)|ensembl:ENST00000485511(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q14738|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9634600|reactome:R-HSA-9648025|refseq:NP_001257405.1|dip:DIP-29961N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:tQnhuUL/6Iuhcyu/B41Me1LWpr89606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:O43815-2	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-1266294|ensembl:ENSP00000368513	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:o43815-2(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	intact:EBI-1046642(strn_human)|ensembl:ENSG00000115808(gene)|ensembl:ENST00000379213(transcript)|uniprotkb:O43815-2(isoform-parent)	psi-mi:"MI:0469"(intact)	-	isoform-comment:No experimental confirmation available.	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:6MwK0aY1uqeiOfAmKgQF/j3oNJw9606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:Q59GV6	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-1773535	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:q59gv6_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	refseq:NP_001034966.1|interpro:IPR020472|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|go:"GO:0005516"(calmodulin binding)|go:"GO:0016020"(membrane)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:WDFWyHzzBAV9/p99Alv7pgpO4es9606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:Q13136	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-745426|uniprotkb:Q8N4I2|uniprotkb:Q14567|uniprotkb:A6NLE3|uniprotkb:Q13135|intact:EBI-28983934|ensembl:ENSP00000253925	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:lipa1_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1(gene name synonym)|uniprotkb:LAR-interacting protein 1(gene name synonym)|uniprotkb:PPFIA1(gene name)|psi-mi:PPFIA1(display_short)|uniprotkb:LIP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	refseq:NP_003617.1|refseq:NP_803172.1|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-388844|ensembl:ENSP00000253925|ensembl:ENST00000389547|ensembl:ENSP00000374198|ensembl:ENSG00000131626(gene)|ensembl:ENST00000253925(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030438|interpro:IPR037620|interpro:IPR037621|interpro:IPR037622|mint:Q13136|rcsb pdb:1N7F|reactome:R-HSA-181429|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|reactome:R-HSA-181430|reactome:R-HSA-210500	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:uLKfBaRJRh4tvNCQ8WP7rnfrmrU9606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:Q96D88	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-1773641	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:q96d88_human(display_long)|uniprotkb:PRR14(gene name)|psi-mi:PRR14(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	interpro:IPR026320|interpro:IPR028149	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:CRfilJwrpiV1TDz10FL5BYpGDEA9606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:Q13362	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-1266156|uniprotkb:B4DYJ8|uniprotkb:F5GWP3|uniprotkb:Q14391|uniprotkb:Q15060|uniprotkb:Q15174|uniprotkb:B5BUA5|intact:EBI-2556020|uniprotkb:Q6ZN33|ensembl:ENSP00000333905	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:2a5g_human(display_long)|uniprotkb:PPP2R5C(gene name)|psi-mi:PPP2R5C(display_short)|uniprotkb:KIAA0044(gene name synonym)|uniprotkb:PP2A B subunit isoform B'-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-gamma(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-29(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	refseq:NP_002710.2|refseq:NP_848701.1|refseq:NP_848702.1|refseq:NP_001155197.1|refseq:NP_001155198.1|refseq:XP_011535222.1|refseq:XP_005267884.1|dip:DIP-39401N|ensembl:ENSG00000078304(gene)|ensembl:ENST00000334743(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q13362|rcsb pdb:2IAE|rcsb pdb:2JAK|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3FGA|rcsb pdb:5JJA|rcsb pdb:5K6S|rcsb pdb:5SW9|rcsb pdb:5SWF|rcsb pdb:6OYL|rcsb pdb:6TOQ|rcsb pdb:6VOY|rcsb pdb:6VRO|rcsb pdb:6Z2Y|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-141444|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:vKPPLnEfyCzEZ2O5lrQDCRghiV09606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:P63151	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-1048931|uniprotkb:P50409|uniprotkb:Q00007|uniprotkb:B2RBU8|intact:EBI-2556013|uniprotkb:B4E1T7|ensembl:ENSP00000370113	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:2aba_human(display_long)|uniprotkb:PPP2R2A(gene name)|psi-mi:PPP2R2A(display_short)|uniprotkb:PP2A subunit B isoform alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	refseq:NP_001171062.1|refseq:NP_002708.1|ensembl:ENSG00000221914(gene)|ensembl:ENST00000380737(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043278"(response to morphine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:P63151|rcsb pdb:3DW8|reactome:R-HSA-2995383|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-975957|dip:DIP-29398N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:evS6klM2alZXtMthVsshKkrNgiA9606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:Q13033-2	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-1053876|intact:EBI-27830295|ensembl:ENSP00000347909	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:q13033-2(display_long)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	intact:EBI-1053857(strn3_human)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000355683(transcript)|uniprotkb:Q13033-2(isoform-parent)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:iNOxFiYQux+p8PBw6q2rZ6W1YRM9606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:Q9BRV8	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:P50990	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:Q16537	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-968374|uniprotkb:B7ZAW5|uniprotkb:J3KQN6|ensembl:ENSP00000337641|uniprotkb:Q52LW4|uniprotkb:A4FU37|uniprotkb:B7ZKK8|intact:EBI-10962508|uniprotkb:B7ZKK9	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:2a5e_human(display_long)|uniprotkb:PPP2R5E(gene name)|psi-mi:PPP2R5E(display_short)|uniprotkb:PP2A B subunit isoform B'-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-epsilon(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	ensembl:ENSG00000154001(gene)|ensembl:ENST00000337537(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR016024(Armadillo-type fold)|mint:Q16537|reactome:R-HSA-141444|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025|interpro:IPR011989(Armadillo-like helical)|refseq:NP_006237.1|refseq:NP_001269108.1|refseq:NP_001269109.1|refseq:NP_001269110.1|refseq:NP_001269111.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:m6vjnzx9eg+HpXrI2KKBLPbObzA9606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P67775	uniprotkb:P30153	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773521|imex:IM-9155-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	intact-crc:EDE9C1514CAF29D8|rigid:BeXP/QOgx1zPw7hWPZ/mVzbAd5g	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:Q5FBB7-6	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-989114|ensembl:ENSP00000410458	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:q5fbb7-6(display_long)|uniprotkb:SGO1(gene name)|psi-mi:SGO1(display_short)|uniprotkb:SGOL1(gene name synonym)|uniprotkb:Serologically defined breast cancer antigen NY-BR-85(gene name synonym)|uniprotkb:Shugoshin-like 1(gene name synonym)|uniprotkb:1AB(isoform synonym)|uniprotkb:SgoL1-A1(isoform synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	intact:EBI-989069(sgol1_human)|ensembl:ENSG00000129810(gene)|ensembl:ENST00000412997(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:eGoNXNboUZb0xzdLaTgPrujYwkU9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:Q9UHV9	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-359873|uniprotkb:Q9P0P7|uniprotkb:Q9UN05|ensembl:ENSP00000356989	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:pfd2_human(display_long)|uniprotkb:HSPC231(orf name)|uniprotkb:PFDN2(gene name)|psi-mi:PFDN2(display_short)|uniprotkb:PFD2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	refseq:NP_036526.2|refseq:XP_011507926.1|ensembl:ENSG00000143256(gene)|ensembl:ENST00000368010(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR027235|mint:Q9UHV9|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|dip:DIP-27557N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:rgr14h3vGyzHxHoNJtlHBQkvhUE9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:Q14BN4-1	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-1517328|ensembl:ENSP00000499241	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:q14bn4-1(display_long)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|intact:EBI-1043216(isoform-parent)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:Q59GV6	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-1773535	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:q59gv6_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	refseq:NP_001034966.1|interpro:IPR020472|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|go:"GO:0005516"(calmodulin binding)|go:"GO:0016020"(membrane)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:WDFWyHzzBAV9/p99Alv7pgpO4es9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:Q14738-1	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-396575|ensembl:ENSP00000417963	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:q14738-1(display_long)|uniprotkb:PPP2R5D(gene name)|psi-mi:PPP2R5D(display_short)|uniprotkb:PP2A B subunit isoform B'-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-delta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	intact:EBI-396563(2a5d_human)|ensembl:ENSG00000112640(gene)|ensembl:ENST00000485511(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:tQnhuUL/6Iuhcyu/B41Me1LWpr89606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:Q5VSL9-1	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-1773601|ensembl:ENSP00000358810	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:q5vsl9-1(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	intact:EBI-1773588(isoform-parent)|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:Q16537	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-968374|uniprotkb:B7ZAW5|uniprotkb:J3KQN6|ensembl:ENSP00000337641|uniprotkb:Q52LW4|uniprotkb:A4FU37|uniprotkb:B7ZKK8|intact:EBI-10962508|uniprotkb:B7ZKK9	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:2a5e_human(display_long)|uniprotkb:PPP2R5E(gene name)|psi-mi:PPP2R5E(display_short)|uniprotkb:PP2A B subunit isoform B'-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-epsilon(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	ensembl:ENSG00000154001(gene)|ensembl:ENST00000337537(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR016024(Armadillo-type fold)|mint:Q16537|reactome:R-HSA-141444|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025|interpro:IPR011989(Armadillo-like helical)|refseq:NP_006237.1|refseq:NP_001269108.1|refseq:NP_001269109.1|refseq:NP_001269110.1|refseq:NP_001269111.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:m6vjnzx9eg+HpXrI2KKBLPbObzA9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:Q96D88	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-1773641	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:q96d88_human(display_long)|uniprotkb:PRR14(gene name)|psi-mi:PRR14(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	interpro:IPR026320|interpro:IPR028149	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:CRfilJwrpiV1TDz10FL5BYpGDEA9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:P63151	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-1048931|uniprotkb:P50409|uniprotkb:Q00007|uniprotkb:B2RBU8|intact:EBI-2556013|uniprotkb:B4E1T7|ensembl:ENSP00000370113	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:2aba_human(display_long)|uniprotkb:PPP2R2A(gene name)|psi-mi:PPP2R2A(display_short)|uniprotkb:PP2A subunit B isoform alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	refseq:NP_001171062.1|refseq:NP_002708.1|ensembl:ENSG00000221914(gene)|ensembl:ENST00000380737(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043278"(response to morphine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:P63151|rcsb pdb:3DW8|reactome:R-HSA-2995383|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-975957|dip:DIP-29398N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:evS6klM2alZXtMthVsshKkrNgiA9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:Q86XL3-2	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-1773634	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:q86xl3-2(display_long)|uniprotkb:ANKLE2(gene name)|psi-mi:ANKLE2(display_short)|uniprotkb:KIAA0692(gene name synonym)|uniprotkb:LEM domain-containing protein 4(gene name synonym)|uniprotkb:LEM4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	intact:EBI-1773621(isoform-parent)	psi-mi:"MI:0469"(intact)	-	isoform-comment:No experimental confirmation available.	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:eRtFUd6vfg1I3BLaP6ExtSScac09606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:P61758	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-357430|ensembl:ENSP00000286428|uniprotkb:Q15765|uniprotkb:O55228|uniprotkb:Q5JT81|uniprotkb:Q86X96|uniprotkb:B2R8L5|uniprotkb:B4DWR3|uniprotkb:F5H2A7	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:pfd3_human(display_long)|uniprotkb:VBP1(gene name)|psi-mi:VBP1(display_short)|uniprotkb:PFDN3(gene name synonym)|uniprotkb:von Hippel-Lindau-binding protein 1(gene name synonym)|uniprotkb:HIBBJ46(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	ensembl:ENSG00000155959(gene)|ensembl:ENST00000286428(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006457"(protein folding)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016655(Prefoldin, subunit 3)|mint:P61758|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|refseq:NP_003363.1|refseq:NP_001290472.1|refseq:NP_001290474.1|dip:DIP-46479N|refseq:NP_001290473.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:wHq+HRvhqfKwOaKtONGJdfETQxo9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:O15212	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-356973|ensembl:ENSP00000363734|ensembl:ENSP00000363735|ensembl:ENSP00000363738|ensembl:ENSP00000372694|ensembl:ENSP00000378563|ensembl:ENSP00000382314|ensembl:ENSP00000382316|ensembl:ENSP00000395462|ensembl:ENSP00000398171|ensembl:ENSP00000400152|ensembl:ENSP00000402212|ensembl:ENSP00000402553|ensembl:ENSP00000403771|ensembl:ENSP00000404773|ensembl:ENSP00000412319|ensembl:ENSP00000415678|ensembl:ENSP00000447540|ensembl:ENSP00000448607|ensembl:ENSP00000448784|ensembl:ENSP00000449925	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:pfd6_human(display_long)|uniprotkb:PFDN6(gene name)|psi-mi:PFDN6(display_short)|uniprotkb:HKE2(gene name synonym)|uniprotkb:PFD6(gene name synonym)|uniprotkb:Protein Ke2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	refseq:NP_001172110.1|refseq:NP_055075.1|refseq:NP_001252524.1|refseq:NP_001252525.1|dip:DIP-50304N|ensembl:ENSG00000204220(gene)|ensembl:ENSG00000206283(gene)|ensembl:ENSG00000224782(gene)|ensembl:ENSG00000235692(gene)|ensembl:ENSG00000237335(gene)|ensembl:ENST00000374606(transcript)|ensembl:ENST00000374607(transcript)|ensembl:ENST00000374610(transcript)|ensembl:ENST00000383207(transcript)|ensembl:ENST00000395131(transcript)|ensembl:ENST00000399383(transcript)|ensembl:ENST00000399385(transcript)|ensembl:ENST00000412289(transcript)|ensembl:ENST00000425878(transcript)|ensembl:ENST00000431830(transcript)|ensembl:ENST00000432391(transcript)|ensembl:ENST00000442285(transcript)|ensembl:ENST00000445559(transcript)|ensembl:ENST00000448594(transcript)|ensembl:ENST00000451970(transcript)|ensembl:ENST00000452658(transcript)|ensembl:ENST00000547641(transcript)|ensembl:ENST00000547952(transcript)|ensembl:ENST00000548040(transcript)|ensembl:ENST00000552711(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|mint:O15212|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957	psi-mi:"MI:0469"(intact)	-	crc64:8F138EAAE512A312	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:t7Z68vuvmprxLIGDh4JhqCGvX+A9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:Q5THK1-1	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-1773559|ensembl:ENSP00000331845	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:q5thk1-1(display_long)|uniprotkb:PRR14L(gene name)|psi-mi:PRR14L(display_short)|uniprotkb:C22orf30(gene name synonym)|uniprotkb:Proline rich 14-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	intact:EBI-1773550(isoform-parent)|ensembl:ENSG00000183530(gene)|ensembl:ENST00000327423(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:JPwD2Kz4L2brrLfT41iriYT2Pos9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:Q99471	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-357275|ensembl:ENSP00000334188|ensembl:ENSP00000447942|intact:EBI-1047551|uniprotkb:A8K9A8|uniprotkb:Q54AA8|uniprotkb:Q9C083|uniprotkb:Q9C084	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:pfd5_human(display_long)|uniprotkb:c-Myc-binding protein Mm-1(gene name synonym)|uniprotkb:PFDN5(gene name)|psi-mi:PFDN5(display_short)|uniprotkb:MM1(gene name synonym)|uniprotkb:Myc modulator 1(gene name synonym)|uniprotkb:PFD5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	ensembl:ENSG00000123349(gene)|ensembl:ENST00000334478(transcript)|ensembl:ENST00000551018(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR011599(Prefoldin alpha subunit)|mint:Q99471|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|refseq:NP_002615.2|refseq:NP_665904.1|dip:DIP-28155N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:Cm4km207qcfDJYRUCIwUxMBT4tE9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:Q13362-1	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-1266170|ensembl:ENSP00000333905	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:q13362-1(display_long)|uniprotkb:PPP2R5C(gene name)|psi-mi:PPP2R5C(display_short)|uniprotkb:KIAA0044(gene name synonym)|uniprotkb:PP2A B subunit isoform B'-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-gamma(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-29(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	intact:EBI-1266156(2a5g_human)|ensembl:ENST00000334743(transcript)|ensembl:ENSG00000078304(gene)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:vKPPLnEfyCzEZ2O5lrQDCRghiV09606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:Q9BRV8-1	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-1773655|ensembl:ENSP00000060969	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:q9brv8-1(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	intact:EBI-1773646(isoform-parent)|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:P30154	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:P48643	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:Q9Y570	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-1772895|uniprotkb:Q8WYG8|uniprotkb:Q9NVT5|uniprotkb:Q9UI18|uniprotkb:B3KMU6|uniprotkb:B5MEE7|uniprotkb:J3QT22|ensembl:ENSP00000329867	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:ppme1_human(display_long)|uniprotkb:PPME1(gene name)|psi-mi:PPME1(display_short)|uniprotkb:PME1(gene name synonym)|uniprotkb:PP2593(orf name)|uniprotkb:PRO0750(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	refseq:NP_057231.1|refseq:NP_001258522.1|ensembl:ENSG00000214517(gene)|ensembl:ENST00000328257(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006482"(protein demethylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051722"(protein C-terminal methylesterase activity)|go:"GO:0051723"(protein methylesterase activity)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR016812(Protein phosphatase methylesterase, eukaryotic)|interpro:IPR029058|rcsb pdb:3C5V|rcsb pdb:3C5W|reactome:R-HSA-69273	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:ZOIwpvvy8nrnGzuNkEu7AZn0JuA9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:P17987	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:P78371	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:Q9Y3A3	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:P78318	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-1055954|uniprotkb:Q8TAB2|ensembl:ENSP00000348784|ensembl:ENSP00000363661	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:igbp1_human(display_long)|uniprotkb:IGBP1(gene name)|psi-mi:IGBP1(display_short)|uniprotkb:IBP1(gene name synonym)|uniprotkb:CD79a-binding protein 1(gene name synonym)|uniprotkb:B-cell signal transduction molecule alpha 4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-16(gene name synonym)|uniprotkb:Protein phosphatase 2/4/6 regulatory subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	refseq:NP_001542.1|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511|mint:P78318|rcsb pdb:4IYP|ensembl:ENSG00000089289(gene)|ensembl:ENST00000342206(transcript)|ensembl:ENST00000356413(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042113"(B cell activation)|refseq:XP_016884978.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:N8w92upYivqH3rjdqNbAcIjDu7I9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:P49368	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:P50990	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:O43815-2	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-1266294|ensembl:ENSP00000368513	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:o43815-2(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	intact:EBI-1046642(strn_human)|ensembl:ENSG00000115808(gene)|ensembl:ENST00000379213(transcript)|uniprotkb:O43815-2(isoform-parent)	psi-mi:"MI:0469"(intact)	-	isoform-comment:No experimental confirmation available.	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:6MwK0aY1uqeiOfAmKgQF/j3oNJw9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:P50991	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:Q99832	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:Q13136	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-745426|uniprotkb:Q8N4I2|uniprotkb:Q14567|uniprotkb:A6NLE3|uniprotkb:Q13135|intact:EBI-28983934|ensembl:ENSP00000253925	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:lipa1_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1(gene name synonym)|uniprotkb:LAR-interacting protein 1(gene name synonym)|uniprotkb:PPFIA1(gene name)|psi-mi:PPFIA1(display_short)|uniprotkb:LIP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	refseq:NP_003617.1|refseq:NP_803172.1|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-388844|ensembl:ENSP00000253925|ensembl:ENST00000389547|ensembl:ENSP00000374198|ensembl:ENSG00000131626(gene)|ensembl:ENST00000253925(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030438|interpro:IPR037620|interpro:IPR037621|interpro:IPR037622|mint:Q13136|rcsb pdb:1N7F|reactome:R-HSA-181429|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|reactome:R-HSA-181430|reactome:R-HSA-210500	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:uLKfBaRJRh4tvNCQ8WP7rnfrmrU9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:P30153	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:Q13033-2	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-1053876|intact:EBI-27830295|ensembl:ENSP00000347909	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:q13033-2(display_long)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	intact:EBI-1053857(strn3_human)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000355683(transcript)|uniprotkb:Q13033-2(isoform-parent)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:iNOxFiYQux+p8PBw6q2rZ6W1YRM9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P62714	uniprotkb:P40227	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773687|imex:IM-9155-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2019/04/15	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	intact-crc:5F004B6BF9D955BE|rigid:WyBKBLUiphfw5DZuF9jw4kbCFLQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P30153	uniprotkb:Q5FBB7-6	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-989114|ensembl:ENSP00000410458	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:q5fbb7-6(display_long)|uniprotkb:SGO1(gene name)|psi-mi:SGO1(display_short)|uniprotkb:SGOL1(gene name synonym)|uniprotkb:Serologically defined breast cancer antigen NY-BR-85(gene name synonym)|uniprotkb:Shugoshin-like 1(gene name synonym)|uniprotkb:1AB(isoform synonym)|uniprotkb:SgoL1-A1(isoform synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773734|imex:IM-9155-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	intact:EBI-989069(sgol1_human)|ensembl:ENSG00000129810(gene)|ensembl:ENST00000412997(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:eGoNXNboUZb0xzdLaTgPrujYwkU9606	intact-crc:E9A45B502107F600|rigid:aS1Y5QQzB+YTnRMRd4kJFSZ18S0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P30153	uniprotkb:P67775	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773734|imex:IM-9155-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	intact-crc:E9A45B502107F600|rigid:aS1Y5QQzB+YTnRMRd4kJFSZ18S0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P30153	uniprotkb:Q13136-1	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-745441|ensembl:ENSP00000253925	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:q13136-1(display_long)|uniprotkb:LAR-interacting protein 1b(isoform synonym)|uniprotkb:LIP.1b(isoform synonym)|uniprotkb:b(isoform synonym)|uniprotkb:PPFIA1(gene name)|psi-mi:PPFIA1(display_short)|uniprotkb:LIP1(gene name synonym)|uniprotkb:LAR-interacting protein 1(gene name synonym)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773734|imex:IM-9155-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	intact:EBI-745426(lipa1_human)|ensembl:ENSG00000131626(gene)|ensembl:ENST00000253925(transcript)	psi-mi:"MI:0469"(intact)	-	isoform-comment:No experimental confirmation available	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:uLKfBaRJRh4tvNCQ8WP7rnfrmrU9606	intact-crc:E9A45B502107F600|rigid:aS1Y5QQzB+YTnRMRd4kJFSZ18S0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P30153	uniprotkb:Q9Y570-1	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-1772913|ensembl:ENSP00000329867	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:q9y570-1(display_long)|uniprotkb:PPME1(gene name)|psi-mi:PPME1(display_short)|uniprotkb:PME1(gene name synonym)|uniprotkb:PP2593(orf name)|uniprotkb:PRO0750(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773734|imex:IM-9155-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	intact:EBI-1772895(isoform-parent)|ensembl:ENSG00000214517(gene)|ensembl:ENST00000328257(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:ZOIwpvvy8nrnGzuNkEu7AZn0JuA9606	intact-crc:E9A45B502107F600|rigid:aS1Y5QQzB+YTnRMRd4kJFSZ18S0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P30153	uniprotkb:Q66LE6	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773734|imex:IM-9155-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606	intact-crc:E9A45B502107F600|rigid:aS1Y5QQzB+YTnRMRd4kJFSZ18S0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P30153	uniprotkb:Q9Y3A3-1	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-713946|ensembl:ENSP00000315702	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:q9y3a3-1(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773734|imex:IM-9155-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	intact:EBI-713935(mob3_human)|ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606	intact-crc:E9A45B502107F600|rigid:aS1Y5QQzB+YTnRMRd4kJFSZ18S0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P30153	uniprotkb:Q59GV6	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-1773535	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:q59gv6_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773734|imex:IM-9155-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	refseq:NP_001034966.1|interpro:IPR020472|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|go:"GO:0005516"(calmodulin binding)|go:"GO:0016020"(membrane)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:WDFWyHzzBAV9/p99Alv7pgpO4es9606	intact-crc:E9A45B502107F600|rigid:aS1Y5QQzB+YTnRMRd4kJFSZ18S0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P30153	uniprotkb:P63151	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-1048931|uniprotkb:P50409|uniprotkb:Q00007|uniprotkb:B2RBU8|intact:EBI-2556013|uniprotkb:B4E1T7|ensembl:ENSP00000370113	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:2aba_human(display_long)|uniprotkb:PPP2R2A(gene name)|psi-mi:PPP2R2A(display_short)|uniprotkb:PP2A subunit B isoform alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773734|imex:IM-9155-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	refseq:NP_001171062.1|refseq:NP_002708.1|ensembl:ENSG00000221914(gene)|ensembl:ENST00000380737(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043278"(response to morphine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:P63151|rcsb pdb:3DW8|reactome:R-HSA-2995383|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-975957|dip:DIP-29398N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:evS6klM2alZXtMthVsshKkrNgiA9606	intact-crc:E9A45B502107F600|rigid:aS1Y5QQzB+YTnRMRd4kJFSZ18S0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P30153	uniprotkb:Q13033-2	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-1053876|intact:EBI-27830295|ensembl:ENSP00000347909	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:q13033-2(display_long)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773734|imex:IM-9155-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	intact:EBI-1053857(strn3_human)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000355683(transcript)|uniprotkb:Q13033-2(isoform-parent)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:iNOxFiYQux+p8PBw6q2rZ6W1YRM9606	intact-crc:E9A45B502107F600|rigid:aS1Y5QQzB+YTnRMRd4kJFSZ18S0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P30153	uniprotkb:O43815-1	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-1266291|ensembl:ENSP00000263918	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:o43815-1(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773734|imex:IM-9155-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	intact:EBI-1046642(strn_human)|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606	intact-crc:E9A45B502107F600|rigid:aS1Y5QQzB+YTnRMRd4kJFSZ18S0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P30153	uniprotkb:Q9Y580	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-746903|uniprotkb:Q9NUT4|uniprotkb:B2R6K8|ensembl:ENSP00000439918	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:rbm7_human(display_long)|uniprotkb:RNA-binding motif protein 7(gene name synonym)|uniprotkb:RBM7(gene name)|psi-mi:RBM7(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773734|imex:IM-9155-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	refseq:NP_001272974.1|refseq:NP_001272975.1|refseq:NP_001272976.1|refseq:NP_001272977.1|refseq:NP_057174.1|ensembl:ENSG00000076053(gene)|ensembl:ENST00000540163(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0017069"(snRNA binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034500|interpro:IPR035979|mint:Q9Y580|rcsb pdb:2M8H|rcsb pdb:5IQQ|rcsb pdb:5LXR|rcsb pdb:5LXY|dip:DIP-48833N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:d39RjBQTHAVQlOsmrxMX0NCR8CU9606	intact-crc:E9A45B502107F600|rigid:aS1Y5QQzB+YTnRMRd4kJFSZ18S0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P30153	uniprotkb:Q86XL3-2	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-1773634	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:q86xl3-2(display_long)|uniprotkb:ANKLE2(gene name)|psi-mi:ANKLE2(display_short)|uniprotkb:KIAA0692(gene name synonym)|uniprotkb:LEM domain-containing protein 4(gene name synonym)|uniprotkb:LEM4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773734|imex:IM-9155-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	intact:EBI-1773621(isoform-parent)	psi-mi:"MI:0469"(intact)	-	isoform-comment:No experimental confirmation available.	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:eRtFUd6vfg1I3BLaP6ExtSScac09606	intact-crc:E9A45B502107F600|rigid:aS1Y5QQzB+YTnRMRd4kJFSZ18S0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P30153	uniprotkb:Q9NUC0	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-1773811|uniprotkb:B2RD32|ensembl:ENSP00000355979|ensembl:ENSP00000486369	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:srtd4_human(display_long)|uniprotkb:SERTAD4(gene name)|psi-mi:SERTAD4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773734|imex:IM-9155-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	refseq:NP_062551.1|ensembl:ENSG00000082497(gene)|ensembl:ENSG00000281230(gene)|ensembl:ENST00000367012(transcript)|ensembl:ENST00000630425(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR009263(SERTA)|interpro:IPR029708	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:us8AIu8sIAtj+ZOqwAH2vzWE0ik9606	intact-crc:E9A45B502107F600|rigid:aS1Y5QQzB+YTnRMRd4kJFSZ18S0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P30153	uniprotkb:Q14BN4-1	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-1517328|ensembl:ENSP00000499241	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:q14bn4-1(display_long)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773734|imex:IM-9155-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|intact:EBI-1043216(isoform-parent)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606	intact-crc:E9A45B502107F600|rigid:aS1Y5QQzB+YTnRMRd4kJFSZ18S0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P30153	uniprotkb:Q6NZY4-1	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-1263069|ensembl:ENSP00000488055|ensembl:ENSP00000500728	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:q6nzy4-1(display_long)|uniprotkb:ZCCHC8(gene name)|psi-mi:ZCCHC8(display_short)|uniprotkb:TRAMP-like complex RNA-binding factor ZCCHC8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773734|imex:IM-9155-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	intact:EBI-1263058(zchc8_human)|ensembl:ENSG00000033030(gene)|ensembl:ENST00000633063(transcript)|ensembl:ENST00000672018(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:dtjoaLAUgEGavPmqaJLPnLPHLP49606	intact-crc:E9A45B502107F600|rigid:aS1Y5QQzB+YTnRMRd4kJFSZ18S0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P30153	uniprotkb:Q5VSL9-1	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-1773601|ensembl:ENSP00000358810	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:q5vsl9-1(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773734|imex:IM-9155-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	intact:EBI-1773588(isoform-parent)|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606	intact-crc:E9A45B502107F600|rigid:aS1Y5QQzB+YTnRMRd4kJFSZ18S0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P30153	uniprotkb:Q13362-1	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-1266170|ensembl:ENSP00000333905	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:q13362-1(display_long)|uniprotkb:PPP2R5C(gene name)|psi-mi:PPP2R5C(display_short)|uniprotkb:KIAA0044(gene name synonym)|uniprotkb:PP2A B subunit isoform B'-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-gamma(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-29(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773734|imex:IM-9155-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	intact:EBI-1266156(2a5g_human)|ensembl:ENST00000334743(transcript)|ensembl:ENSG00000078304(gene)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:vKPPLnEfyCzEZ2O5lrQDCRghiV09606	intact-crc:E9A45B502107F600|rigid:aS1Y5QQzB+YTnRMRd4kJFSZ18S0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P30153	uniprotkb:Q5THK1-1	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-1773559|ensembl:ENSP00000331845	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:q5thk1-1(display_long)|uniprotkb:PRR14L(gene name)|psi-mi:PRR14L(display_short)|uniprotkb:C22orf30(gene name synonym)|uniprotkb:Proline rich 14-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773734|imex:IM-9155-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	intact:EBI-1773550(isoform-parent)|ensembl:ENSG00000183530(gene)|ensembl:ENST00000327423(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:JPwD2Kz4L2brrLfT41iriYT2Pos9606	intact-crc:E9A45B502107F600|rigid:aS1Y5QQzB+YTnRMRd4kJFSZ18S0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P30153	uniprotkb:P06702	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-1055001|uniprotkb:Q6FGA1|uniprotkb:Q9NYM0|uniprotkb:Q9UCJ1|uniprotkb:D3DV36|ensembl:ENSP00000357727	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:s10a9_human(display_long)|uniprotkb:S100 calcium-binding protein A9(gene name synonym)|uniprotkb:Calgranulin-B(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 14(gene name synonym)|uniprotkb:Leukocyte L1 complex heavy chain(gene name synonym)|uniprotkb:Calprotectin L1H subunit(gene name synonym)|uniprotkb:S100A9(gene name)|psi-mi:S100A9(display_short)|uniprotkb:CAGB(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:MRP14(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773734|imex:IM-9155-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	refseq:NP_002956.1|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5I8N|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENSG00000163220(gene)|ensembl:ENST00000368738(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0035821"(modulation of process of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045113"(regulation of integrin biosynthetic process)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|mint:P06702|rcsb pdb:1IRJ|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030054"(cell junction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|dip:DIP-1166N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:IGnX4DSnv8xMr5pY4T7X7vYos5A9606	intact-crc:E9A45B502107F600|rigid:aS1Y5QQzB+YTnRMRd4kJFSZ18S0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P30153	uniprotkb:P42285	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-347612|uniprotkb:Q2M386|uniprotkb:Q6MZZ8|uniprotkb:Q6P170|uniprotkb:Q8N5R0|uniprotkb:Q8TAG2|ensembl:ENSP00000230640	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:mtrex_human(display_long)|uniprotkb:MTREX(gene name)|psi-mi:MTREX(display_short)|uniprotkb:DOB1(gene name synonym)|uniprotkb:KIAA0052(gene name synonym)|uniprotkb:MTR4(gene name synonym)|uniprotkb:SKIV2L2(gene name synonym)|uniprotkb:Superkiller viralicidic activity 2-like 2(gene name synonym)|uniprotkb:TRAMP-like complex helicase(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DOB1(gene name synonym)|uniprotkb:ATP-dependent RNA helicase SKIV2L2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773734|imex:IM-9155-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	refseq:NP_056175.3|ensembl:ENSG00000039123(gene)|ensembl:ENST00000230640(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0031499"(TRAMP complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|mint:P42285|rcsb pdb:6C90|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6IEG|rcsb pdb:6IEH|rcsb pdb:6RO1|reactome:R-HSA-6791226|reactome:R-HSA-72163	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:bQdFDddFhetSp+CJ1S7Q5cm+g0k9606	intact-crc:E9A45B502107F600|rigid:aS1Y5QQzB+YTnRMRd4kJFSZ18S0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P30153	uniprotkb:Q14738-1	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-396575|ensembl:ENSP00000417963	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:q14738-1(display_long)|uniprotkb:PPP2R5D(gene name)|psi-mi:PPP2R5D(display_short)|uniprotkb:PP2A B subunit isoform B'-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-delta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773734|imex:IM-9155-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	intact:EBI-396563(2a5d_human)|ensembl:ENSG00000112640(gene)|ensembl:ENST00000485511(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:tQnhuUL/6Iuhcyu/B41Me1LWpr89606	intact-crc:E9A45B502107F600|rigid:aS1Y5QQzB+YTnRMRd4kJFSZ18S0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P30153	uniprotkb:Q16537	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-968374|uniprotkb:B7ZAW5|uniprotkb:J3KQN6|ensembl:ENSP00000337641|uniprotkb:Q52LW4|uniprotkb:A4FU37|uniprotkb:B7ZKK8|intact:EBI-10962508|uniprotkb:B7ZKK9	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:2a5e_human(display_long)|uniprotkb:PPP2R5E(gene name)|psi-mi:PPP2R5E(display_short)|uniprotkb:PP2A B subunit isoform B'-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-epsilon(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773734|imex:IM-9155-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	ensembl:ENSG00000154001(gene)|ensembl:ENST00000337537(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR016024(Armadillo-type fold)|mint:Q16537|reactome:R-HSA-141444|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025|interpro:IPR011989(Armadillo-like helical)|refseq:NP_006237.1|refseq:NP_001269108.1|refseq:NP_001269109.1|refseq:NP_001269110.1|refseq:NP_001269111.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:m6vjnzx9eg+HpXrI2KKBLPbObzA9606	intact-crc:E9A45B502107F600|rigid:aS1Y5QQzB+YTnRMRd4kJFSZ18S0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P30153	uniprotkb:Q96D88	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-1773641	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:q96d88_human(display_long)|uniprotkb:PRR14(gene name)|psi-mi:PRR14(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773734|imex:IM-9155-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	interpro:IPR026320|interpro:IPR028149	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:CRfilJwrpiV1TDz10FL5BYpGDEA9606	intact-crc:E9A45B502107F600|rigid:aS1Y5QQzB+YTnRMRd4kJFSZ18S0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9H7D0	uniprotkb:P30154	intact:EBI-1773858|uniprotkb:Q5XKD5|uniprotkb:Q6AI11|uniprotkb:Q6PJS6|uniprotkb:Q6ZTS6|uniprotkb:B2RNY0|ensembl:ENSP00000276440|intact:EBI-28975706	intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193	psi-mi:dock5_human(display_long)|uniprotkb:DOCK5(gene name)|psi-mi:DOCK5(display_short)	psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773888|imex:IM-9155-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000276440|ensembl:ENST00000481100|ensembl:ENSP00000429737|refseq:NP_079216.4|ensembl:ENSG00000147459(gene)|ensembl:ENST00000276440(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016477"(cell migration)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904694"(negative regulation of vascular associated smooth muscle contraction)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR030717|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|mint:Q9H7D0|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-983231|go:"GO:0007264"(small GTPase mediated signal transduction)	dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:/+sUfMB7hLZjdyhsMQ8WKJoXXLU9606	rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606	intact-crc:AFB394321E25D6EA|rigid:2HW/hw0gVSpviR9MdXduCDCdk5I	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9H7D0	uniprotkb:P17987	intact:EBI-1773858|uniprotkb:Q5XKD5|uniprotkb:Q6AI11|uniprotkb:Q6PJS6|uniprotkb:Q6ZTS6|uniprotkb:B2RNY0|ensembl:ENSP00000276440|intact:EBI-28975706	intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334	psi-mi:dock5_human(display_long)|uniprotkb:DOCK5(gene name)|psi-mi:DOCK5(display_short)	psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773888|imex:IM-9155-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000276440|ensembl:ENST00000481100|ensembl:ENSP00000429737|refseq:NP_079216.4|ensembl:ENSG00000147459(gene)|ensembl:ENST00000276440(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016477"(cell migration)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904694"(negative regulation of vascular associated smooth muscle contraction)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR030717|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|mint:Q9H7D0|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-983231|go:"GO:0007264"(small GTPase mediated signal transduction)	refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:/+sUfMB7hLZjdyhsMQ8WKJoXXLU9606	rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606	intact-crc:AFB394321E25D6EA|rigid:2HW/hw0gVSpviR9MdXduCDCdk5I	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9H7D0	uniprotkb:P15924-1	intact:EBI-1773858|uniprotkb:Q5XKD5|uniprotkb:Q6AI11|uniprotkb:Q6PJS6|uniprotkb:Q6ZTS6|uniprotkb:B2RNY0|ensembl:ENSP00000276440|intact:EBI-28975706	intact:EBI-355054|ensembl:ENSP00000369129	psi-mi:dock5_human(display_long)|uniprotkb:DOCK5(gene name)|psi-mi:DOCK5(display_short)	psi-mi:p15924-1(display_long)|uniprotkb:DP1(isoform synonym)|uniprotkb:DSP(gene name)|psi-mi:DSP(display_short)|uniprotkb:250/210 kDa paraneoplastic pemphigus antigen(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773888|imex:IM-9155-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000276440|ensembl:ENST00000481100|ensembl:ENSP00000429737|refseq:NP_079216.4|ensembl:ENSG00000147459(gene)|ensembl:ENST00000276440(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016477"(cell migration)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904694"(negative regulation of vascular associated smooth muscle contraction)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR030717|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|mint:Q9H7D0|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-983231|go:"GO:0007264"(small GTPase mediated signal transduction)	intact:EBI-355041(desp_human)|ensembl:ENSG00000096696(gene)|ensembl:ENST00000379802(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:/+sUfMB7hLZjdyhsMQ8WKJoXXLU9606	rogid:enapEqSoyTSLfPEQUAopkGpdxbo9606	intact-crc:AFB394321E25D6EA|rigid:2HW/hw0gVSpviR9MdXduCDCdk5I	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9H7D0	uniprotkb:Q99832	intact:EBI-1773858|uniprotkb:Q5XKD5|uniprotkb:Q6AI11|uniprotkb:Q6PJS6|uniprotkb:Q6ZTS6|uniprotkb:B2RNY0|ensembl:ENSP00000276440|intact:EBI-28975706	intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091	psi-mi:dock5_human(display_long)|uniprotkb:DOCK5(gene name)|psi-mi:DOCK5(display_short)	psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773888|imex:IM-9155-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000276440|ensembl:ENST00000481100|ensembl:ENSP00000429737|refseq:NP_079216.4|ensembl:ENSG00000147459(gene)|ensembl:ENST00000276440(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016477"(cell migration)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904694"(negative regulation of vascular associated smooth muscle contraction)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR030717|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|mint:Q9H7D0|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-983231|go:"GO:0007264"(small GTPase mediated signal transduction)	dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:/+sUfMB7hLZjdyhsMQ8WKJoXXLU9606	rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606	intact-crc:AFB394321E25D6EA|rigid:2HW/hw0gVSpviR9MdXduCDCdk5I	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9H7D0	uniprotkb:P40227	intact:EBI-1773858|uniprotkb:Q5XKD5|uniprotkb:Q6AI11|uniprotkb:Q6PJS6|uniprotkb:Q6ZTS6|uniprotkb:B2RNY0|ensembl:ENSP00000276440|intact:EBI-28975706	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2	psi-mi:dock5_human(display_long)|uniprotkb:DOCK5(gene name)|psi-mi:DOCK5(display_short)	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773888|imex:IM-9155-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000276440|ensembl:ENST00000481100|ensembl:ENSP00000429737|refseq:NP_079216.4|ensembl:ENSG00000147459(gene)|ensembl:ENST00000276440(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016477"(cell migration)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904694"(negative regulation of vascular associated smooth muscle contraction)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR030717|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|mint:Q9H7D0|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-983231|go:"GO:0007264"(small GTPase mediated signal transduction)	refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:/+sUfMB7hLZjdyhsMQ8WKJoXXLU9606	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	intact-crc:AFB394321E25D6EA|rigid:2HW/hw0gVSpviR9MdXduCDCdk5I	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9H7D0	uniprotkb:Q9BXL8	intact:EBI-1773858|uniprotkb:Q5XKD5|uniprotkb:Q6AI11|uniprotkb:Q6PJS6|uniprotkb:Q6ZTS6|uniprotkb:B2RNY0|ensembl:ENSP00000276440|intact:EBI-28975706	intact:EBI-1773949|uniprotkb:Q8TB18|uniprotkb:Q9NWK7|ensembl:ENSP00000337226|ensembl:ENSP00000376369	psi-mi:dock5_human(display_long)|uniprotkb:DOCK5(gene name)|psi-mi:DOCK5(display_short)	psi-mi:cdca4_human(display_long)|uniprotkb:CDCA4(gene name)|psi-mi:CDCA4(display_short)|uniprotkb:HEPP(gene name synonym)|uniprotkb:Hematopoietic progenitor protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773888|imex:IM-9155-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000276440|ensembl:ENST00000481100|ensembl:ENSP00000429737|refseq:NP_079216.4|ensembl:ENSG00000147459(gene)|ensembl:ENST00000276440(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016477"(cell migration)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904694"(negative regulation of vascular associated smooth muscle contraction)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR030717|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|mint:Q9H7D0|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-983231|go:"GO:0007264"(small GTPase mediated signal transduction)	refseq:NP_060425.2|refseq:NP_663747.1|ensembl:ENSG00000170779(gene)|ensembl:ENST00000336219(transcript)|ensembl:ENST00000392590(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0048096"|interpro:IPR009263(SERTA)|mint:Q9BXL8	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:/+sUfMB7hLZjdyhsMQ8WKJoXXLU9606	rogid:sxwZ0Yw0uG+MjnhKtVv+8PHvPCo9606	intact-crc:AFB394321E25D6EA|rigid:2HW/hw0gVSpviR9MdXduCDCdk5I	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9H7D0	uniprotkb:P50990	intact:EBI-1773858|uniprotkb:Q5XKD5|uniprotkb:Q6AI11|uniprotkb:Q6PJS6|uniprotkb:Q6ZTS6|uniprotkb:B2RNY0|ensembl:ENSP00000276440|intact:EBI-28975706	intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788	psi-mi:dock5_human(display_long)|uniprotkb:DOCK5(gene name)|psi-mi:DOCK5(display_short)	psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773888|imex:IM-9155-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000276440|ensembl:ENST00000481100|ensembl:ENSP00000429737|refseq:NP_079216.4|ensembl:ENSG00000147459(gene)|ensembl:ENST00000276440(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016477"(cell migration)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904694"(negative regulation of vascular associated smooth muscle contraction)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR030717|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|mint:Q9H7D0|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-983231|go:"GO:0007264"(small GTPase mediated signal transduction)	refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:/+sUfMB7hLZjdyhsMQ8WKJoXXLU9606	rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606	intact-crc:AFB394321E25D6EA|rigid:2HW/hw0gVSpviR9MdXduCDCdk5I	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9H7D0	uniprotkb:P48643	intact:EBI-1773858|uniprotkb:Q5XKD5|uniprotkb:Q6AI11|uniprotkb:Q6PJS6|uniprotkb:Q6ZTS6|uniprotkb:B2RNY0|ensembl:ENSP00000276440|intact:EBI-28975706	intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8	psi-mi:dock5_human(display_long)|uniprotkb:DOCK5(gene name)|psi-mi:DOCK5(display_short)	psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773888|imex:IM-9155-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000276440|ensembl:ENST00000481100|ensembl:ENSP00000429737|refseq:NP_079216.4|ensembl:ENSG00000147459(gene)|ensembl:ENST00000276440(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016477"(cell migration)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904694"(negative regulation of vascular associated smooth muscle contraction)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR030717|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|mint:Q9H7D0|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-983231|go:"GO:0007264"(small GTPase mediated signal transduction)	refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:/+sUfMB7hLZjdyhsMQ8WKJoXXLU9606	rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606	intact-crc:AFB394321E25D6EA|rigid:2HW/hw0gVSpviR9MdXduCDCdk5I	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9H7D0	uniprotkb:P50991	intact:EBI-1773858|uniprotkb:Q5XKD5|uniprotkb:Q6AI11|uniprotkb:Q6PJS6|uniprotkb:Q6ZTS6|uniprotkb:B2RNY0|ensembl:ENSP00000276440|intact:EBI-28975706	intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958	psi-mi:dock5_human(display_long)|uniprotkb:DOCK5(gene name)|psi-mi:DOCK5(display_short)	psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773888|imex:IM-9155-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000276440|ensembl:ENST00000481100|ensembl:ENSP00000429737|refseq:NP_079216.4|ensembl:ENSG00000147459(gene)|ensembl:ENST00000276440(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016477"(cell migration)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904694"(negative regulation of vascular associated smooth muscle contraction)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR030717|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|mint:Q9H7D0|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-983231|go:"GO:0007264"(small GTPase mediated signal transduction)	refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:/+sUfMB7hLZjdyhsMQ8WKJoXXLU9606	rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606	intact-crc:AFB394321E25D6EA|rigid:2HW/hw0gVSpviR9MdXduCDCdk5I	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9H7D0	uniprotkb:P49368	intact:EBI-1773858|uniprotkb:Q5XKD5|uniprotkb:Q6AI11|uniprotkb:Q6PJS6|uniprotkb:Q6ZTS6|uniprotkb:B2RNY0|ensembl:ENSP00000276440|intact:EBI-28975706	intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688	psi-mi:dock5_human(display_long)|uniprotkb:DOCK5(gene name)|psi-mi:DOCK5(display_short)	psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773888|imex:IM-9155-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000276440|ensembl:ENST00000481100|ensembl:ENSP00000429737|refseq:NP_079216.4|ensembl:ENSG00000147459(gene)|ensembl:ENST00000276440(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016477"(cell migration)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904694"(negative regulation of vascular associated smooth muscle contraction)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR030717|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|mint:Q9H7D0|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-983231|go:"GO:0007264"(small GTPase mediated signal transduction)	refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:/+sUfMB7hLZjdyhsMQ8WKJoXXLU9606	rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606	intact-crc:AFB394321E25D6EA|rigid:2HW/hw0gVSpviR9MdXduCDCdk5I	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9H7D0	uniprotkb:P78371	intact:EBI-1773858|uniprotkb:Q5XKD5|uniprotkb:Q6AI11|uniprotkb:Q6PJS6|uniprotkb:Q6ZTS6|uniprotkb:B2RNY0|ensembl:ENSP00000276440|intact:EBI-28975706	intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300	psi-mi:dock5_human(display_long)|uniprotkb:DOCK5(gene name)|psi-mi:DOCK5(display_short)	psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773888|imex:IM-9155-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000276440|ensembl:ENST00000481100|ensembl:ENSP00000429737|refseq:NP_079216.4|ensembl:ENSG00000147459(gene)|ensembl:ENST00000276440(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016477"(cell migration)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904694"(negative regulation of vascular associated smooth muscle contraction)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR030717|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|mint:Q9H7D0|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-983231|go:"GO:0007264"(small GTPase mediated signal transduction)	refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:/+sUfMB7hLZjdyhsMQ8WKJoXXLU9606	rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606	intact-crc:AFB394321E25D6EA|rigid:2HW/hw0gVSpviR9MdXduCDCdk5I	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9H7D0	uniprotkb:P30153	intact:EBI-1773858|uniprotkb:Q5XKD5|uniprotkb:Q6AI11|uniprotkb:Q6PJS6|uniprotkb:Q6ZTS6|uniprotkb:B2RNY0|ensembl:ENSP00000276440|intact:EBI-28975706	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	psi-mi:dock5_human(display_long)|uniprotkb:DOCK5(gene name)|psi-mi:DOCK5(display_short)	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773888|imex:IM-9155-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000276440|ensembl:ENST00000481100|ensembl:ENSP00000429737|refseq:NP_079216.4|ensembl:ENSG00000147459(gene)|ensembl:ENST00000276440(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016477"(cell migration)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904694"(negative regulation of vascular associated smooth muscle contraction)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR030717|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|mint:Q9H7D0|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-983231|go:"GO:0007264"(small GTPase mediated signal transduction)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:/+sUfMB7hLZjdyhsMQ8WKJoXXLU9606	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	intact-crc:AFB394321E25D6EA|rigid:2HW/hw0gVSpviR9MdXduCDCdk5I	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9H7D0	uniprotkb:P67775	intact:EBI-1773858|uniprotkb:Q5XKD5|uniprotkb:Q6AI11|uniprotkb:Q6PJS6|uniprotkb:Q6ZTS6|uniprotkb:B2RNY0|ensembl:ENSP00000276440|intact:EBI-28975706	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	psi-mi:dock5_human(display_long)|uniprotkb:DOCK5(gene name)|psi-mi:DOCK5(display_short)	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773888|imex:IM-9155-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000276440|ensembl:ENST00000481100|ensembl:ENSP00000429737|refseq:NP_079216.4|ensembl:ENSG00000147459(gene)|ensembl:ENST00000276440(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016477"(cell migration)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904694"(negative regulation of vascular associated smooth muscle contraction)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR030717|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|mint:Q9H7D0|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-983231|go:"GO:0007264"(small GTPase mediated signal transduction)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:/+sUfMB7hLZjdyhsMQ8WKJoXXLU9606	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	intact-crc:AFB394321E25D6EA|rigid:2HW/hw0gVSpviR9MdXduCDCdk5I	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q96BD8	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-741854|uniprotkb:B2R9Y6|uniprotkb:B4E0P4|ensembl:ENSP00000285116|ensembl:ENSP00000381470|ensembl:ENSP00000458992|ensembl:ENSP00000478259	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:ska1_human(display_long)|uniprotkb:SKA1(gene name)|psi-mi:SKA1(display_short)|uniprotkb:C18orf24(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773971|imex:IM-9155-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001034624.1|refseq:NP_659497.1|ensembl:ENSG00000154839(gene)|ensembl:ENSG00000262634(gene)|ensembl:ENST00000285116(transcript)|ensembl:ENST00000398452(transcript)|ensembl:ENST00000571751(transcript)|ensembl:ENST00000616604(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|interpro:IPR009829(Protein of unknown function DUF1395)|interpro:IPR042031|mint:Q96BD8|rcsb pdb:4AJ5|rcsb pdb:4C9Y|rcsb pdb:4CA0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:Z7y57MeLsUJK0R9JNqHJNBbKr/89606	intact-crc:92C54D736E1C75F4|rigid:CB3K+4RlVPg11CGbDG3EcKyv6yQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q9BXL8	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1773949|uniprotkb:Q8TB18|uniprotkb:Q9NWK7|ensembl:ENSP00000337226|ensembl:ENSP00000376369	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:cdca4_human(display_long)|uniprotkb:CDCA4(gene name)|psi-mi:CDCA4(display_short)|uniprotkb:HEPP(gene name synonym)|uniprotkb:Hematopoietic progenitor protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773971|imex:IM-9155-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_060425.2|refseq:NP_663747.1|ensembl:ENSG00000170779(gene)|ensembl:ENST00000336219(transcript)|ensembl:ENST00000392590(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0048096"|interpro:IPR009263(SERTA)|mint:Q9BXL8	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:sxwZ0Yw0uG+MjnhKtVv+8PHvPCo9606	intact-crc:92C54D736E1C75F4|rigid:CB3K+4RlVPg11CGbDG3EcKyv6yQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:O95816	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773971|imex:IM-9155-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606	intact-crc:92C54D736E1C75F4|rigid:CB3K+4RlVPg11CGbDG3EcKyv6yQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P50990	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773971|imex:IM-9155-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606	intact-crc:92C54D736E1C75F4|rigid:CB3K+4RlVPg11CGbDG3EcKyv6yQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P49368	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773971|imex:IM-9155-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606	intact-crc:92C54D736E1C75F4|rigid:CB3K+4RlVPg11CGbDG3EcKyv6yQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P48643	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773971|imex:IM-9155-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606	intact-crc:92C54D736E1C75F4|rigid:CB3K+4RlVPg11CGbDG3EcKyv6yQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q9Y4B5	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-302423|uniprotkb:Q6ZMQ9|uniprotkb:Q8IWA9|intact:EBI-28975975|ensembl:ENSP00000305027|intact:EBI-2554582|uniprotkb:E9PAY7	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:mtcl1_human(display_long)|uniprotkb:MTCL1(gene name)|psi-mi:MTCL1(display_short)|uniprotkb:CCDC165(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 165(gene name synonym)|uniprotkb:KIAA0802(gene name synonym)|uniprotkb:PAR-1-interacting protein(gene name synonym)|uniprotkb:SOGA family member 2(gene name synonym)|uniprotkb:SOGA2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773971|imex:IM-9155-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_056025.2|ensembl:ENSG00000168502(gene)|ensembl:ENST00000306329(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008017"(microtubule binding)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030496"(midbody)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097427"(microtubule bundle)|go:"GO:2000576"(obsolete positive regulation of microtubule motor activity)|interpro:IPR027881|interpro:IPR027882|ensembl:ENSP00000305027|ensembl:ENST00000359865|ensembl:ENSP00000352927|ensembl:ENST00000400050|ensembl:ENSP00000382924|ensembl:ENSP00000429556|ensembl:ENST00000518815|ensembl:ENSP00000463465|ensembl:ENST00000517570|refseq:XP_005258156.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:RxNB5mpEiLNQpsyKLfaw0LyqsVU9606	intact-crc:92C54D736E1C75F4|rigid:CB3K+4RlVPg11CGbDG3EcKyv6yQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P17987	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773971|imex:IM-9155-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606	intact-crc:92C54D736E1C75F4|rigid:CB3K+4RlVPg11CGbDG3EcKyv6yQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P63167	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773971|imex:IM-9155-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606	intact-crc:92C54D736E1C75F4|rigid:CB3K+4RlVPg11CGbDG3EcKyv6yQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q9ULJ3	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1051048|intact:EBI-1774011|uniprotkb:Q5R2W1|uniprotkb:Q5R2W2|uniprotkb:Q6P4R0|ensembl:ENSP00000308759|ensembl:ENSP00000381512|ensembl:ENSP00000381523	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:zbt21_human(display_long)|uniprotkb:ZBTB21(gene name)|psi-mi:ZBTB21(display_short)|uniprotkb:KIAA1227(gene name synonym)|uniprotkb:ZNF295(gene name synonym)|uniprotkb:Zinc finger protein 295(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773971|imex:IM-9155-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001091872.1|refseq:NP_065778.3|refseq:XP_011527890.1|refseq:XP_011527892.1|refseq:NP_001307658.1|refseq:NP_001307660.1|refseq:XP_016883849.1|refseq:XP_016883850.1|refseq:NP_001091873.1|refseq:XP_005261178.1|ensembl:ENST00000310826(transcript)|ensembl:ENST00000398499(transcript)|ensembl:ENST00000398511(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0031208"(POZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041011|rcsb pdb:1WJP|ensembl:ENSG00000173276(gene)|ensembl:ENSP00000308759|ensembl:ENSP00000381512|ensembl:ENST00000398505|ensembl:ENSP00000381517|ensembl:ENSP00000381523	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:0yEEz3zJHqnDrVQdftkyVhL6PKU9606	intact-crc:92C54D736E1C75F4|rigid:CB3K+4RlVPg11CGbDG3EcKyv6yQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P40227	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773971|imex:IM-9155-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	intact-crc:92C54D736E1C75F4|rigid:CB3K+4RlVPg11CGbDG3EcKyv6yQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P50991	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773971|imex:IM-9155-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606	intact-crc:92C54D736E1C75F4|rigid:CB3K+4RlVPg11CGbDG3EcKyv6yQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P47756-2	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-353608|ensembl:ENSP00000264202	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:p47756-2(display_long)|uniprotkb:CAPZB(gene name)|psi-mi:CAPZB(display_short)|uniprotkb:CapZ beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773971|imex:IM-9155-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-353595(capzb_human)|ensembl:ENSG00000077549(gene)|ensembl:ENST00000264202(transcript)|uniprotkb:P47756-2(isoform-parent)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:48IQ1CJkjL9DdUW66uFlFKhRWxo9606	intact-crc:92C54D736E1C75F4|rigid:CB3K+4RlVPg11CGbDG3EcKyv6yQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P78371	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773971|imex:IM-9155-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606	intact-crc:92C54D736E1C75F4|rigid:CB3K+4RlVPg11CGbDG3EcKyv6yQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P67775	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773971|imex:IM-9155-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	intact-crc:92C54D736E1C75F4|rigid:CB3K+4RlVPg11CGbDG3EcKyv6yQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q8WVK7	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1773994|uniprotkb:A6NIL3|uniprotkb:B3KPL3|uniprotkb:E9PCB8|ensembl:ENSP00000333433	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:ska2_human(display_long)|uniprotkb:SKA2(gene name)|psi-mi:SKA2(display_short)|uniprotkb:FAM33A(gene name synonym)|uniprotkb:Protein FAM33A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773971|imex:IM-9155-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001094065.1|refseq:NP_872426.1|ensembl:ENSG00000182628(gene)|ensembl:ENST00000330137(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0051301"(cell division)|interpro:IPR026762|interpro:IPR042091|mint:Q8WVK7|rcsb pdb:4AJ5|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:OxuqjB9I67fkmxHRa5g1u6KMvAg9606	intact-crc:92C54D736E1C75F4|rigid:CB3K+4RlVPg11CGbDG3EcKyv6yQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P30154	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773971|imex:IM-9155-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606	intact-crc:92C54D736E1C75F4|rigid:CB3K+4RlVPg11CGbDG3EcKyv6yQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q8IX90-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1773985|ensembl:ENSP00000319417	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q8ix90-1(display_long)|uniprotkb:SKA3(gene name)|psi-mi:SKA3(display_short)|uniprotkb:C13orf3(gene name synonym)|uniprotkb:RAMA1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773971|imex:IM-9155-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-1773976(isoform-parent)|ensembl:ENSG00000165480(gene)|ensembl:ENST00000314759(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:F3lm7ntNHVutZ+X66pTMEfyyJ+E9606	intact-crc:92C54D736E1C75F4|rigid:CB3K+4RlVPg11CGbDG3EcKyv6yQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q9NUC0	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1773811|uniprotkb:B2RD32|ensembl:ENSP00000355979|ensembl:ENSP00000486369	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:srtd4_human(display_long)|uniprotkb:SERTAD4(gene name)|psi-mi:SERTAD4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773971|imex:IM-9155-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_062551.1|ensembl:ENSG00000082497(gene)|ensembl:ENSG00000281230(gene)|ensembl:ENST00000367012(transcript)|ensembl:ENST00000630425(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR009263(SERTA)|interpro:IPR029708	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:us8AIu8sIAtj+ZOqwAH2vzWE0ik9606	intact-crc:92C54D736E1C75F4|rigid:CB3K+4RlVPg11CGbDG3EcKyv6yQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P62714	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773971|imex:IM-9155-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	intact-crc:92C54D736E1C75F4|rigid:CB3K+4RlVPg11CGbDG3EcKyv6yQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P30153	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773971|imex:IM-9155-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	intact-crc:92C54D736E1C75F4|rigid:CB3K+4RlVPg11CGbDG3EcKyv6yQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q99832	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773971|imex:IM-9155-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606	intact-crc:92C54D736E1C75F4|rigid:CB3K+4RlVPg11CGbDG3EcKyv6yQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:B2RTY4	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-355398|uniprotkb:B0I1T5|uniprotkb:Q14787|uniprotkb:Q3YLD7|uniprotkb:Q3YLD8|uniprotkb:Q6P986|uniprotkb:Q9H8T5|uniprotkb:Q9NTG2|uniprotkb:Q9NUY2|uniprotkb:Q9UEP3|intact:EBI-720284|uniprotkb:Q9UNJ2|uniprotkb:C9IYB3|uniprotkb:C9JA86|intact:EBI-28974247|ensembl:ENSP00000348349|ensembl:ENSP00000398250	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:myo9a_human(display_long)|uniprotkb:MYO9A(gene name)|psi-mi:MYO9A(display_short)|uniprotkb:MYR7(gene name synonym)|uniprotkb:Unconventional myosin-9a(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773971|imex:IM-9155-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_008832.2|ensembl:ENSP00000348349|ensembl:ENST00000424560|ensembl:ENSP00000399162|ensembl:ENSP00000398250|refseq:XP_006720602.1|ensembl:ENSG00000066933(gene)|ensembl:ENST00000356056(transcript)|ensembl:ENST00000444904(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0034329"(cell junction assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028558|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013424	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:xiEo+vK0qu9k1RrBjoOrgp7Wm+g9606	intact-crc:92C54D736E1C75F4|rigid:CB3K+4RlVPg11CGbDG3EcKyv6yQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q5VY09	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1774000|uniprotkb:Q8WY68|uniprotkb:Q9NY49|uniprotkb:Q9NZP9|uniprotkb:B2RBV3|ensembl:ENSP00000356549	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:ier5_human(display_long)|uniprotkb:IER5(gene name)|psi-mi:IER5(display_short)|uniprotkb:PP4583(orf name)|uniprotkb:SBBI48(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1773971|imex:IM-9155-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_057629.2|ensembl:ENSG00000162783(gene)|ensembl:ENST00000367577(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1900036"(positive regulation of cellular response to heat)|interpro:IPR008653(Immediate early response)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:D297tz5ThLd1cqyA1Fo/g5/nuN89606	intact-crc:92C54D736E1C75F4|rigid:CB3K+4RlVPg11CGbDG3EcKyv6yQ	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y2T4	uniprotkb:P50991	intact:EBI-1774058|uniprotkb:Q9H3G7|uniprotkb:A8MSY7|uniprotkb:Q7Z4V7|uniprotkb:Q8NEC4|uniprotkb:B7Z3Y1|ensembl:ENSP00000372042	intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958	psi-mi:2abg_human(display_long)|uniprotkb:PPP2R2C(gene name)|psi-mi:PPP2R2C(display_short)|uniprotkb:PP2A subunit B isoform gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-gamma(gene name synonym)|uniprotkb:IMYPNO1(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-gamma(gene name synonym)	psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774070|imex:IM-9155-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193925.1|refseq:NP_870991.1|refseq:NP_001193923.1|refseq:NP_001193924.1|refseq:NP_065149.2|ensembl:ENSG00000074211(gene)|ensembl:ENST00000382599(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:cJj+2y6EJdczJD6SnOBRa2hl3ys9606	rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606	intact-crc:B889A2EB44498BDA|rigid:mIi+tbM0S0CsekQ1oKcz8pfK6GI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y2T4	uniprotkb:P67775	intact:EBI-1774058|uniprotkb:Q9H3G7|uniprotkb:A8MSY7|uniprotkb:Q7Z4V7|uniprotkb:Q8NEC4|uniprotkb:B7Z3Y1|ensembl:ENSP00000372042	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	psi-mi:2abg_human(display_long)|uniprotkb:PPP2R2C(gene name)|psi-mi:PPP2R2C(display_short)|uniprotkb:PP2A subunit B isoform gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-gamma(gene name synonym)|uniprotkb:IMYPNO1(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-gamma(gene name synonym)	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774070|imex:IM-9155-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193925.1|refseq:NP_870991.1|refseq:NP_001193923.1|refseq:NP_001193924.1|refseq:NP_065149.2|ensembl:ENSG00000074211(gene)|ensembl:ENST00000382599(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:cJj+2y6EJdczJD6SnOBRa2hl3ys9606	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	intact-crc:B889A2EB44498BDA|rigid:mIi+tbM0S0CsekQ1oKcz8pfK6GI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y2T4	uniprotkb:P50990	intact:EBI-1774058|uniprotkb:Q9H3G7|uniprotkb:A8MSY7|uniprotkb:Q7Z4V7|uniprotkb:Q8NEC4|uniprotkb:B7Z3Y1|ensembl:ENSP00000372042	intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788	psi-mi:2abg_human(display_long)|uniprotkb:PPP2R2C(gene name)|psi-mi:PPP2R2C(display_short)|uniprotkb:PP2A subunit B isoform gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-gamma(gene name synonym)|uniprotkb:IMYPNO1(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-gamma(gene name synonym)	psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774070|imex:IM-9155-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193925.1|refseq:NP_870991.1|refseq:NP_001193923.1|refseq:NP_001193924.1|refseq:NP_065149.2|ensembl:ENSG00000074211(gene)|ensembl:ENST00000382599(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:cJj+2y6EJdczJD6SnOBRa2hl3ys9606	rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606	intact-crc:B889A2EB44498BDA|rigid:mIi+tbM0S0CsekQ1oKcz8pfK6GI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y2T4	uniprotkb:P49368	intact:EBI-1774058|uniprotkb:Q9H3G7|uniprotkb:A8MSY7|uniprotkb:Q7Z4V7|uniprotkb:Q8NEC4|uniprotkb:B7Z3Y1|ensembl:ENSP00000372042	intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688	psi-mi:2abg_human(display_long)|uniprotkb:PPP2R2C(gene name)|psi-mi:PPP2R2C(display_short)|uniprotkb:PP2A subunit B isoform gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-gamma(gene name synonym)|uniprotkb:IMYPNO1(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-gamma(gene name synonym)	psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774070|imex:IM-9155-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193925.1|refseq:NP_870991.1|refseq:NP_001193923.1|refseq:NP_001193924.1|refseq:NP_065149.2|ensembl:ENSG00000074211(gene)|ensembl:ENST00000382599(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:cJj+2y6EJdczJD6SnOBRa2hl3ys9606	rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606	intact-crc:B889A2EB44498BDA|rigid:mIi+tbM0S0CsekQ1oKcz8pfK6GI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y2T4	uniprotkb:Q99832	intact:EBI-1774058|uniprotkb:Q9H3G7|uniprotkb:A8MSY7|uniprotkb:Q7Z4V7|uniprotkb:Q8NEC4|uniprotkb:B7Z3Y1|ensembl:ENSP00000372042	intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091	psi-mi:2abg_human(display_long)|uniprotkb:PPP2R2C(gene name)|psi-mi:PPP2R2C(display_short)|uniprotkb:PP2A subunit B isoform gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-gamma(gene name synonym)|uniprotkb:IMYPNO1(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-gamma(gene name synonym)	psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774070|imex:IM-9155-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193925.1|refseq:NP_870991.1|refseq:NP_001193923.1|refseq:NP_001193924.1|refseq:NP_065149.2|ensembl:ENSG00000074211(gene)|ensembl:ENST00000382599(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:cJj+2y6EJdczJD6SnOBRa2hl3ys9606	rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606	intact-crc:B889A2EB44498BDA|rigid:mIi+tbM0S0CsekQ1oKcz8pfK6GI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y2T4	uniprotkb:O95816	intact:EBI-1774058|uniprotkb:Q9H3G7|uniprotkb:A8MSY7|uniprotkb:Q7Z4V7|uniprotkb:Q8NEC4|uniprotkb:B7Z3Y1|ensembl:ENSP00000372042	intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407	psi-mi:2abg_human(display_long)|uniprotkb:PPP2R2C(gene name)|psi-mi:PPP2R2C(display_short)|uniprotkb:PP2A subunit B isoform gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-gamma(gene name synonym)|uniprotkb:IMYPNO1(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-gamma(gene name synonym)	psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774070|imex:IM-9155-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193925.1|refseq:NP_870991.1|refseq:NP_001193923.1|refseq:NP_001193924.1|refseq:NP_065149.2|ensembl:ENSG00000074211(gene)|ensembl:ENST00000382599(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:cJj+2y6EJdczJD6SnOBRa2hl3ys9606	rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606	intact-crc:B889A2EB44498BDA|rigid:mIi+tbM0S0CsekQ1oKcz8pfK6GI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y2T4	uniprotkb:P40227	intact:EBI-1774058|uniprotkb:Q9H3G7|uniprotkb:A8MSY7|uniprotkb:Q7Z4V7|uniprotkb:Q8NEC4|uniprotkb:B7Z3Y1|ensembl:ENSP00000372042	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2	psi-mi:2abg_human(display_long)|uniprotkb:PPP2R2C(gene name)|psi-mi:PPP2R2C(display_short)|uniprotkb:PP2A subunit B isoform gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-gamma(gene name synonym)|uniprotkb:IMYPNO1(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-gamma(gene name synonym)	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774070|imex:IM-9155-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193925.1|refseq:NP_870991.1|refseq:NP_001193923.1|refseq:NP_001193924.1|refseq:NP_065149.2|ensembl:ENSG00000074211(gene)|ensembl:ENST00000382599(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:cJj+2y6EJdczJD6SnOBRa2hl3ys9606	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	intact-crc:B889A2EB44498BDA|rigid:mIi+tbM0S0CsekQ1oKcz8pfK6GI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y2T4	uniprotkb:Q9BXL8	intact:EBI-1774058|uniprotkb:Q9H3G7|uniprotkb:A8MSY7|uniprotkb:Q7Z4V7|uniprotkb:Q8NEC4|uniprotkb:B7Z3Y1|ensembl:ENSP00000372042	intact:EBI-1773949|uniprotkb:Q8TB18|uniprotkb:Q9NWK7|ensembl:ENSP00000337226|ensembl:ENSP00000376369	psi-mi:2abg_human(display_long)|uniprotkb:PPP2R2C(gene name)|psi-mi:PPP2R2C(display_short)|uniprotkb:PP2A subunit B isoform gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-gamma(gene name synonym)|uniprotkb:IMYPNO1(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-gamma(gene name synonym)	psi-mi:cdca4_human(display_long)|uniprotkb:CDCA4(gene name)|psi-mi:CDCA4(display_short)|uniprotkb:HEPP(gene name synonym)|uniprotkb:Hematopoietic progenitor protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774070|imex:IM-9155-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193925.1|refseq:NP_870991.1|refseq:NP_001193923.1|refseq:NP_001193924.1|refseq:NP_065149.2|ensembl:ENSG00000074211(gene)|ensembl:ENST00000382599(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_060425.2|refseq:NP_663747.1|ensembl:ENSG00000170779(gene)|ensembl:ENST00000336219(transcript)|ensembl:ENST00000392590(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0048096"|interpro:IPR009263(SERTA)|mint:Q9BXL8	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:cJj+2y6EJdczJD6SnOBRa2hl3ys9606	rogid:sxwZ0Yw0uG+MjnhKtVv+8PHvPCo9606	intact-crc:B889A2EB44498BDA|rigid:mIi+tbM0S0CsekQ1oKcz8pfK6GI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y2T4	uniprotkb:P30153	intact:EBI-1774058|uniprotkb:Q9H3G7|uniprotkb:A8MSY7|uniprotkb:Q7Z4V7|uniprotkb:Q8NEC4|uniprotkb:B7Z3Y1|ensembl:ENSP00000372042	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	psi-mi:2abg_human(display_long)|uniprotkb:PPP2R2C(gene name)|psi-mi:PPP2R2C(display_short)|uniprotkb:PP2A subunit B isoform gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-gamma(gene name synonym)|uniprotkb:IMYPNO1(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-gamma(gene name synonym)	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774070|imex:IM-9155-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193925.1|refseq:NP_870991.1|refseq:NP_001193923.1|refseq:NP_001193924.1|refseq:NP_065149.2|ensembl:ENSG00000074211(gene)|ensembl:ENST00000382599(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:cJj+2y6EJdczJD6SnOBRa2hl3ys9606	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	intact-crc:B889A2EB44498BDA|rigid:mIi+tbM0S0CsekQ1oKcz8pfK6GI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y2T4	uniprotkb:P17987	intact:EBI-1774058|uniprotkb:Q9H3G7|uniprotkb:A8MSY7|uniprotkb:Q7Z4V7|uniprotkb:Q8NEC4|uniprotkb:B7Z3Y1|ensembl:ENSP00000372042	intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334	psi-mi:2abg_human(display_long)|uniprotkb:PPP2R2C(gene name)|psi-mi:PPP2R2C(display_short)|uniprotkb:PP2A subunit B isoform gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-gamma(gene name synonym)|uniprotkb:IMYPNO1(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-gamma(gene name synonym)	psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774070|imex:IM-9155-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193925.1|refseq:NP_870991.1|refseq:NP_001193923.1|refseq:NP_001193924.1|refseq:NP_065149.2|ensembl:ENSG00000074211(gene)|ensembl:ENST00000382599(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:cJj+2y6EJdczJD6SnOBRa2hl3ys9606	rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606	intact-crc:B889A2EB44498BDA|rigid:mIi+tbM0S0CsekQ1oKcz8pfK6GI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y2T4	uniprotkb:P48643	intact:EBI-1774058|uniprotkb:Q9H3G7|uniprotkb:A8MSY7|uniprotkb:Q7Z4V7|uniprotkb:Q8NEC4|uniprotkb:B7Z3Y1|ensembl:ENSP00000372042	intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8	psi-mi:2abg_human(display_long)|uniprotkb:PPP2R2C(gene name)|psi-mi:PPP2R2C(display_short)|uniprotkb:PP2A subunit B isoform gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-gamma(gene name synonym)|uniprotkb:IMYPNO1(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-gamma(gene name synonym)	psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774070|imex:IM-9155-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193925.1|refseq:NP_870991.1|refseq:NP_001193923.1|refseq:NP_001193924.1|refseq:NP_065149.2|ensembl:ENSG00000074211(gene)|ensembl:ENST00000382599(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:cJj+2y6EJdczJD6SnOBRa2hl3ys9606	rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606	intact-crc:B889A2EB44498BDA|rigid:mIi+tbM0S0CsekQ1oKcz8pfK6GI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y2T4	uniprotkb:P78371	intact:EBI-1774058|uniprotkb:Q9H3G7|uniprotkb:A8MSY7|uniprotkb:Q7Z4V7|uniprotkb:Q8NEC4|uniprotkb:B7Z3Y1|ensembl:ENSP00000372042	intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300	psi-mi:2abg_human(display_long)|uniprotkb:PPP2R2C(gene name)|psi-mi:PPP2R2C(display_short)|uniprotkb:PP2A subunit B isoform gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-gamma(gene name synonym)|uniprotkb:IMYPNO1(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-gamma(gene name synonym)	psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774070|imex:IM-9155-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193925.1|refseq:NP_870991.1|refseq:NP_001193923.1|refseq:NP_001193924.1|refseq:NP_065149.2|ensembl:ENSG00000074211(gene)|ensembl:ENST00000382599(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2015/09/23	rogid:cJj+2y6EJdczJD6SnOBRa2hl3ys9606	rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606	intact-crc:B889A2EB44498BDA|rigid:mIi+tbM0S0CsekQ1oKcz8pfK6GI	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q66LE6	uniprotkb:P42285	intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970	intact:EBI-347612|uniprotkb:Q2M386|uniprotkb:Q6MZZ8|uniprotkb:Q6P170|uniprotkb:Q8N5R0|uniprotkb:Q8TAG2|ensembl:ENSP00000230640	psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym)	psi-mi:mtrex_human(display_long)|uniprotkb:MTREX(gene name)|psi-mi:MTREX(display_short)|uniprotkb:DOB1(gene name synonym)|uniprotkb:KIAA0052(gene name synonym)|uniprotkb:MTR4(gene name synonym)|uniprotkb:SKIV2L2(gene name synonym)|uniprotkb:Superkiller viralicidic activity 2-like 2(gene name synonym)|uniprotkb:TRAMP-like complex helicase(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DOB1(gene name synonym)|uniprotkb:ATP-dependent RNA helicase SKIV2L2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774087|imex:IM-9155-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1	refseq:NP_056175.3|ensembl:ENSG00000039123(gene)|ensembl:ENST00000230640(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0031499"(TRAMP complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|mint:P42285|rcsb pdb:6C90|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6IEG|rcsb pdb:6IEH|rcsb pdb:6RO1|reactome:R-HSA-6791226|reactome:R-HSA-72163	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606	rogid:bQdFDddFhetSp+CJ1S7Q5cm+g0k9606	intact-crc:D351E0D95259FA4E|rigid:RX86xGDc21Tl0pcuxszUUVZwdLM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q66LE6	uniprotkb:P48643	intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970	intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8	psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym)	psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774087|imex:IM-9155-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1	refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606	rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606	intact-crc:D351E0D95259FA4E|rigid:RX86xGDc21Tl0pcuxszUUVZwdLM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q66LE6	uniprotkb:P17987	intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970	intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334	psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym)	psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774087|imex:IM-9155-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1	refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606	rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606	intact-crc:D351E0D95259FA4E|rigid:RX86xGDc21Tl0pcuxszUUVZwdLM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q66LE6	uniprotkb:P60510	intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym)	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774087|imex:IM-9155-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	intact-crc:D351E0D95259FA4E|rigid:RX86xGDc21Tl0pcuxszUUVZwdLM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q66LE6	uniprotkb:Q9Y580	intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970	intact:EBI-746903|uniprotkb:Q9NUT4|uniprotkb:B2R6K8|ensembl:ENSP00000439918	psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym)	psi-mi:rbm7_human(display_long)|uniprotkb:RNA-binding motif protein 7(gene name synonym)|uniprotkb:RBM7(gene name)|psi-mi:RBM7(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774087|imex:IM-9155-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1	refseq:NP_001272974.1|refseq:NP_001272975.1|refseq:NP_001272976.1|refseq:NP_001272977.1|refseq:NP_057174.1|ensembl:ENSG00000076053(gene)|ensembl:ENST00000540163(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0017069"(snRNA binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034500|interpro:IPR035979|mint:Q9Y580|rcsb pdb:2M8H|rcsb pdb:5IQQ|rcsb pdb:5LXR|rcsb pdb:5LXY|dip:DIP-48833N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606	rogid:d39RjBQTHAVQlOsmrxMX0NCR8CU9606	intact-crc:D351E0D95259FA4E|rigid:RX86xGDc21Tl0pcuxszUUVZwdLM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q66LE6	uniprotkb:P40227	intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2	psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym)	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774087|imex:IM-9155-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1	refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	intact-crc:D351E0D95259FA4E|rigid:RX86xGDc21Tl0pcuxszUUVZwdLM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q66LE6	uniprotkb:P67775	intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym)	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774087|imex:IM-9155-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	intact-crc:D351E0D95259FA4E|rigid:RX86xGDc21Tl0pcuxszUUVZwdLM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q66LE6	uniprotkb:P49368	intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970	intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688	psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym)	psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774087|imex:IM-9155-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1	refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606	rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606	intact-crc:D351E0D95259FA4E|rigid:RX86xGDc21Tl0pcuxszUUVZwdLM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q66LE6	uniprotkb:Q9Y570-1	intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970	intact:EBI-1772913|ensembl:ENSP00000329867	psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym)	psi-mi:q9y570-1(display_long)|uniprotkb:PPME1(gene name)|psi-mi:PPME1(display_short)|uniprotkb:PME1(gene name synonym)|uniprotkb:PP2593(orf name)|uniprotkb:PRO0750(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774087|imex:IM-9155-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1	intact:EBI-1772895(isoform-parent)|ensembl:ENSG00000214517(gene)|ensembl:ENST00000328257(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606	rogid:ZOIwpvvy8nrnGzuNkEu7AZn0JuA9606	intact-crc:D351E0D95259FA4E|rigid:RX86xGDc21Tl0pcuxszUUVZwdLM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q66LE6	uniprotkb:P30154	intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970	intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193	psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym)	psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774087|imex:IM-9155-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1	dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606	rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606	intact-crc:D351E0D95259FA4E|rigid:RX86xGDc21Tl0pcuxszUUVZwdLM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q66LE6	uniprotkb:Q6NZY4-1	intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970	intact:EBI-1263069|ensembl:ENSP00000488055|ensembl:ENSP00000500728	psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym)	psi-mi:q6nzy4-1(display_long)|uniprotkb:ZCCHC8(gene name)|psi-mi:ZCCHC8(display_short)|uniprotkb:TRAMP-like complex RNA-binding factor ZCCHC8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774087|imex:IM-9155-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1	intact:EBI-1263058(zchc8_human)|ensembl:ENSG00000033030(gene)|ensembl:ENST00000633063(transcript)|ensembl:ENST00000672018(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606	rogid:dtjoaLAUgEGavPmqaJLPnLPHLP49606	intact-crc:D351E0D95259FA4E|rigid:RX86xGDc21Tl0pcuxszUUVZwdLM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q66LE6	uniprotkb:Q9NPF5	intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970	intact:EBI-399105|uniprotkb:Q0JSM4|uniprotkb:Q5TG41|uniprotkb:Q7Z3H7|uniprotkb:Q9H0S8|uniprotkb:Q9P2C2|uniprotkb:A8K001|uniprotkb:D3DPY8|ensembl:ENSP00000312697|ensembl:ENSP00000354697|ensembl:ENSP00000361363	psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym)	psi-mi:dmap1_human(display_long)|uniprotkb:DMAP1(gene name)|psi-mi:DMAP1(display_short)|uniprotkb:KIAA1425(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774087|imex:IM-9155-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1	refseq:NP_001029195.1|refseq:NP_001029196.1|refseq:NP_061973.1|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR008468(DNA methyltransferase 1-associated 1)|interpro:IPR027109|interpro:IPR032563|mint:Q9NPF5|rcsb pdb:3HM5|rcsb pdb:4IEJ|reactome:R-HSA-3214847|ensembl:ENSG00000178028(gene)|ensembl:ENST00000315913(transcript)|ensembl:ENST00000361745(transcript)|ensembl:ENST00000372289(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006306"(DNA methylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043486"(histone exchange)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:XP_016857297.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606	rogid:ujgZ1NbKKo/pw//CZvIGWfY2ob49606	intact-crc:D351E0D95259FA4E|rigid:RX86xGDc21Tl0pcuxszUUVZwdLM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q66LE6	uniprotkb:P30153	intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym)	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774087|imex:IM-9155-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	intact-crc:D351E0D95259FA4E|rigid:RX86xGDc21Tl0pcuxszUUVZwdLM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q66LE6	uniprotkb:Q99832	intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970	intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091	psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym)	psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774087|imex:IM-9155-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1	dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606	rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606	intact-crc:D351E0D95259FA4E|rigid:RX86xGDc21Tl0pcuxszUUVZwdLM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q66LE6	uniprotkb:Q8WWM7-1	intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970	intact:EBI-948384|ensembl:ENSP00000338718	psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym)	psi-mi:q8wwm7-1(display_long)|uniprotkb:A2D-A(isoform synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774087|imex:IM-9155-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1	ensembl:ENSG00000168488(gene)|ensembl:ENST00000336783(transcript)|intact:EBI-948363(atx2l_human)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606	rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606	intact-crc:D351E0D95259FA4E|rigid:RX86xGDc21Tl0pcuxszUUVZwdLM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q66LE6	uniprotkb:P50991	intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970	intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958	psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym)	psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774087|imex:IM-9155-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1	refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606	rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606	intact-crc:D351E0D95259FA4E|rigid:RX86xGDc21Tl0pcuxszUUVZwdLM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q66LE6	uniprotkb:Q96T67	intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970	intact:EBI-1774091	psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym)	psi-mi:q96t67_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774087|imex:IM-9155-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1	interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606	rogid:D3KPDIKMNVOnbs83TijFmbPtu/89606	intact-crc:D351E0D95259FA4E|rigid:RX86xGDc21Tl0pcuxszUUVZwdLM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q66LE6	uniprotkb:Q8IX90-1	intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970	intact:EBI-1773985|ensembl:ENSP00000319417	psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym)	psi-mi:q8ix90-1(display_long)|uniprotkb:SKA3(gene name)|psi-mi:SKA3(display_short)|uniprotkb:C13orf3(gene name synonym)|uniprotkb:RAMA1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774087|imex:IM-9155-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1	intact:EBI-1773976(isoform-parent)|ensembl:ENSG00000165480(gene)|ensembl:ENST00000314759(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606	rogid:F3lm7ntNHVutZ+X66pTMEfyyJ+E9606	intact-crc:D351E0D95259FA4E|rigid:RX86xGDc21Tl0pcuxszUUVZwdLM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q66LE6	uniprotkb:P78371	intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970	intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300	psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym)	psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774087|imex:IM-9155-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1	refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606	rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606	intact-crc:D351E0D95259FA4E|rigid:RX86xGDc21Tl0pcuxszUUVZwdLM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q66LE6	uniprotkb:P62714	intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym)	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774087|imex:IM-9155-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	intact-crc:D351E0D95259FA4E|rigid:RX86xGDc21Tl0pcuxszUUVZwdLM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q66LE6	uniprotkb:P50990	intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970	intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788	psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym)	psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774087|imex:IM-9155-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1	refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606	rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606	intact-crc:D351E0D95259FA4E|rigid:RX86xGDc21Tl0pcuxszUUVZwdLM	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q15257	uniprotkb:P67775	intact:EBI-1774121|uniprotkb:Q9NNZ7|uniprotkb:Q9NNZ8|uniprotkb:Q9NNZ9|uniprotkb:Q15258|uniprotkb:Q53GZ3|uniprotkb:Q5TZQ2|uniprotkb:Q9BUK1|uniprotkb:B4DXM4|uniprotkb:A2A347|uniprotkb:A9IZU4|ensembl:ENSP00000337448	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	psi-mi:ptpa_human(display_long)|uniprotkb:PTPA(gene name)|psi-mi:PTPA(display_short)|uniprotkb:PP2A, subunit B', PR53 isoform(gene name synonym)|uniprotkb:PPP2R4(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A regulatory subunit 4(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A regulatory subunit B'(gene name synonym)	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774171|imex:IM-9155-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180326.1|refseq:NP_066954.2|refseq:NP_821067.1|refseq:NP_821068.1|refseq:NP_821070.1|refseq:NP_001258761.1|ensembl:ENSG00000119383(gene)|ensembl:ENST00000337738(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2G62|rcsb pdb:2HV6|rcsb pdb:2HV7|rcsb pdb:2IXM|rcsb pdb:4LAC|rcsb pdb:4NY3	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:j4TfEgx2pQ4OgNRd/b77YIiuKVU9606	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	intact-crc:979CC4EDD3E5B458|rigid:C17To84G4sOcNqmzGvALR76T5s4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q15257	uniprotkb:P49368	intact:EBI-1774121|uniprotkb:Q9NNZ7|uniprotkb:Q9NNZ8|uniprotkb:Q9NNZ9|uniprotkb:Q15258|uniprotkb:Q53GZ3|uniprotkb:Q5TZQ2|uniprotkb:Q9BUK1|uniprotkb:B4DXM4|uniprotkb:A2A347|uniprotkb:A9IZU4|ensembl:ENSP00000337448	intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688	psi-mi:ptpa_human(display_long)|uniprotkb:PTPA(gene name)|psi-mi:PTPA(display_short)|uniprotkb:PP2A, subunit B', PR53 isoform(gene name synonym)|uniprotkb:PPP2R4(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A regulatory subunit 4(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A regulatory subunit B'(gene name synonym)	psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774171|imex:IM-9155-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180326.1|refseq:NP_066954.2|refseq:NP_821067.1|refseq:NP_821068.1|refseq:NP_821070.1|refseq:NP_001258761.1|ensembl:ENSG00000119383(gene)|ensembl:ENST00000337738(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2G62|rcsb pdb:2HV6|rcsb pdb:2HV7|rcsb pdb:2IXM|rcsb pdb:4LAC|rcsb pdb:4NY3	refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:j4TfEgx2pQ4OgNRd/b77YIiuKVU9606	rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606	intact-crc:979CC4EDD3E5B458|rigid:C17To84G4sOcNqmzGvALR76T5s4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q15257	uniprotkb:P48643	intact:EBI-1774121|uniprotkb:Q9NNZ7|uniprotkb:Q9NNZ8|uniprotkb:Q9NNZ9|uniprotkb:Q15258|uniprotkb:Q53GZ3|uniprotkb:Q5TZQ2|uniprotkb:Q9BUK1|uniprotkb:B4DXM4|uniprotkb:A2A347|uniprotkb:A9IZU4|ensembl:ENSP00000337448	intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8	psi-mi:ptpa_human(display_long)|uniprotkb:PTPA(gene name)|psi-mi:PTPA(display_short)|uniprotkb:PP2A, subunit B', PR53 isoform(gene name synonym)|uniprotkb:PPP2R4(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A regulatory subunit 4(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A regulatory subunit B'(gene name synonym)	psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774171|imex:IM-9155-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180326.1|refseq:NP_066954.2|refseq:NP_821067.1|refseq:NP_821068.1|refseq:NP_821070.1|refseq:NP_001258761.1|ensembl:ENSG00000119383(gene)|ensembl:ENST00000337738(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2G62|rcsb pdb:2HV6|rcsb pdb:2HV7|rcsb pdb:2IXM|rcsb pdb:4LAC|rcsb pdb:4NY3	refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:j4TfEgx2pQ4OgNRd/b77YIiuKVU9606	rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606	intact-crc:979CC4EDD3E5B458|rigid:C17To84G4sOcNqmzGvALR76T5s4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q15257	uniprotkb:P50990	intact:EBI-1774121|uniprotkb:Q9NNZ7|uniprotkb:Q9NNZ8|uniprotkb:Q9NNZ9|uniprotkb:Q15258|uniprotkb:Q53GZ3|uniprotkb:Q5TZQ2|uniprotkb:Q9BUK1|uniprotkb:B4DXM4|uniprotkb:A2A347|uniprotkb:A9IZU4|ensembl:ENSP00000337448	intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788	psi-mi:ptpa_human(display_long)|uniprotkb:PTPA(gene name)|psi-mi:PTPA(display_short)|uniprotkb:PP2A, subunit B', PR53 isoform(gene name synonym)|uniprotkb:PPP2R4(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A regulatory subunit 4(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A regulatory subunit B'(gene name synonym)	psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774171|imex:IM-9155-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180326.1|refseq:NP_066954.2|refseq:NP_821067.1|refseq:NP_821068.1|refseq:NP_821070.1|refseq:NP_001258761.1|ensembl:ENSG00000119383(gene)|ensembl:ENST00000337738(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2G62|rcsb pdb:2HV6|rcsb pdb:2HV7|rcsb pdb:2IXM|rcsb pdb:4LAC|rcsb pdb:4NY3	refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:j4TfEgx2pQ4OgNRd/b77YIiuKVU9606	rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606	intact-crc:979CC4EDD3E5B458|rigid:C17To84G4sOcNqmzGvALR76T5s4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q15257	uniprotkb:P50991	intact:EBI-1774121|uniprotkb:Q9NNZ7|uniprotkb:Q9NNZ8|uniprotkb:Q9NNZ9|uniprotkb:Q15258|uniprotkb:Q53GZ3|uniprotkb:Q5TZQ2|uniprotkb:Q9BUK1|uniprotkb:B4DXM4|uniprotkb:A2A347|uniprotkb:A9IZU4|ensembl:ENSP00000337448	intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958	psi-mi:ptpa_human(display_long)|uniprotkb:PTPA(gene name)|psi-mi:PTPA(display_short)|uniprotkb:PP2A, subunit B', PR53 isoform(gene name synonym)|uniprotkb:PPP2R4(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A regulatory subunit 4(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A regulatory subunit B'(gene name synonym)	psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774171|imex:IM-9155-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180326.1|refseq:NP_066954.2|refseq:NP_821067.1|refseq:NP_821068.1|refseq:NP_821070.1|refseq:NP_001258761.1|ensembl:ENSG00000119383(gene)|ensembl:ENST00000337738(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2G62|rcsb pdb:2HV6|rcsb pdb:2HV7|rcsb pdb:2IXM|rcsb pdb:4LAC|rcsb pdb:4NY3	refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:j4TfEgx2pQ4OgNRd/b77YIiuKVU9606	rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606	intact-crc:979CC4EDD3E5B458|rigid:C17To84G4sOcNqmzGvALR76T5s4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q15257	uniprotkb:Q99832	intact:EBI-1774121|uniprotkb:Q9NNZ7|uniprotkb:Q9NNZ8|uniprotkb:Q9NNZ9|uniprotkb:Q15258|uniprotkb:Q53GZ3|uniprotkb:Q5TZQ2|uniprotkb:Q9BUK1|uniprotkb:B4DXM4|uniprotkb:A2A347|uniprotkb:A9IZU4|ensembl:ENSP00000337448	intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091	psi-mi:ptpa_human(display_long)|uniprotkb:PTPA(gene name)|psi-mi:PTPA(display_short)|uniprotkb:PP2A, subunit B', PR53 isoform(gene name synonym)|uniprotkb:PPP2R4(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A regulatory subunit 4(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A regulatory subunit B'(gene name synonym)	psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774171|imex:IM-9155-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180326.1|refseq:NP_066954.2|refseq:NP_821067.1|refseq:NP_821068.1|refseq:NP_821070.1|refseq:NP_001258761.1|ensembl:ENSG00000119383(gene)|ensembl:ENST00000337738(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2G62|rcsb pdb:2HV6|rcsb pdb:2HV7|rcsb pdb:2IXM|rcsb pdb:4LAC|rcsb pdb:4NY3	dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:j4TfEgx2pQ4OgNRd/b77YIiuKVU9606	rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606	intact-crc:979CC4EDD3E5B458|rigid:C17To84G4sOcNqmzGvALR76T5s4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q15257	uniprotkb:P17987	intact:EBI-1774121|uniprotkb:Q9NNZ7|uniprotkb:Q9NNZ8|uniprotkb:Q9NNZ9|uniprotkb:Q15258|uniprotkb:Q53GZ3|uniprotkb:Q5TZQ2|uniprotkb:Q9BUK1|uniprotkb:B4DXM4|uniprotkb:A2A347|uniprotkb:A9IZU4|ensembl:ENSP00000337448	intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334	psi-mi:ptpa_human(display_long)|uniprotkb:PTPA(gene name)|psi-mi:PTPA(display_short)|uniprotkb:PP2A, subunit B', PR53 isoform(gene name synonym)|uniprotkb:PPP2R4(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A regulatory subunit 4(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A regulatory subunit B'(gene name synonym)	psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774171|imex:IM-9155-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180326.1|refseq:NP_066954.2|refseq:NP_821067.1|refseq:NP_821068.1|refseq:NP_821070.1|refseq:NP_001258761.1|ensembl:ENSG00000119383(gene)|ensembl:ENST00000337738(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2G62|rcsb pdb:2HV6|rcsb pdb:2HV7|rcsb pdb:2IXM|rcsb pdb:4LAC|rcsb pdb:4NY3	refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:j4TfEgx2pQ4OgNRd/b77YIiuKVU9606	rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606	intact-crc:979CC4EDD3E5B458|rigid:C17To84G4sOcNqmzGvALR76T5s4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q15257	uniprotkb:P40227	intact:EBI-1774121|uniprotkb:Q9NNZ7|uniprotkb:Q9NNZ8|uniprotkb:Q9NNZ9|uniprotkb:Q15258|uniprotkb:Q53GZ3|uniprotkb:Q5TZQ2|uniprotkb:Q9BUK1|uniprotkb:B4DXM4|uniprotkb:A2A347|uniprotkb:A9IZU4|ensembl:ENSP00000337448	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2	psi-mi:ptpa_human(display_long)|uniprotkb:PTPA(gene name)|psi-mi:PTPA(display_short)|uniprotkb:PP2A, subunit B', PR53 isoform(gene name synonym)|uniprotkb:PPP2R4(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A regulatory subunit 4(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A regulatory subunit B'(gene name synonym)	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774171|imex:IM-9155-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180326.1|refseq:NP_066954.2|refseq:NP_821067.1|refseq:NP_821068.1|refseq:NP_821070.1|refseq:NP_001258761.1|ensembl:ENSG00000119383(gene)|ensembl:ENST00000337738(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2G62|rcsb pdb:2HV6|rcsb pdb:2HV7|rcsb pdb:2IXM|rcsb pdb:4LAC|rcsb pdb:4NY3	refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:j4TfEgx2pQ4OgNRd/b77YIiuKVU9606	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	intact-crc:979CC4EDD3E5B458|rigid:C17To84G4sOcNqmzGvALR76T5s4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q15257	uniprotkb:P78371	intact:EBI-1774121|uniprotkb:Q9NNZ7|uniprotkb:Q9NNZ8|uniprotkb:Q9NNZ9|uniprotkb:Q15258|uniprotkb:Q53GZ3|uniprotkb:Q5TZQ2|uniprotkb:Q9BUK1|uniprotkb:B4DXM4|uniprotkb:A2A347|uniprotkb:A9IZU4|ensembl:ENSP00000337448	intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300	psi-mi:ptpa_human(display_long)|uniprotkb:PTPA(gene name)|psi-mi:PTPA(display_short)|uniprotkb:PP2A, subunit B', PR53 isoform(gene name synonym)|uniprotkb:PPP2R4(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A regulatory subunit 4(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A regulatory subunit B'(gene name synonym)	psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774171|imex:IM-9155-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180326.1|refseq:NP_066954.2|refseq:NP_821067.1|refseq:NP_821068.1|refseq:NP_821070.1|refseq:NP_001258761.1|ensembl:ENSG00000119383(gene)|ensembl:ENST00000337738(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2G62|rcsb pdb:2HV6|rcsb pdb:2HV7|rcsb pdb:2IXM|rcsb pdb:4LAC|rcsb pdb:4NY3	refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:j4TfEgx2pQ4OgNRd/b77YIiuKVU9606	rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606	intact-crc:979CC4EDD3E5B458|rigid:C17To84G4sOcNqmzGvALR76T5s4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P60510	uniprotkb:P30153	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774185|imex:IM-9155-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	intact-crc:D3CC1EA20946230A|rigid:HueTCVxmr3zSUkcN0TtLSJRmqa0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P60510	uniprotkb:Q14738-1	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	intact:EBI-396575|ensembl:ENSP00000417963	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:q14738-1(display_long)|uniprotkb:PPP2R5D(gene name)|psi-mi:PPP2R5D(display_short)|uniprotkb:PP2A B subunit isoform B'-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-delta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774185|imex:IM-9155-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	intact:EBI-396563(2a5d_human)|ensembl:ENSG00000112640(gene)|ensembl:ENST00000485511(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rogid:tQnhuUL/6Iuhcyu/B41Me1LWpr89606	intact-crc:D3CC1EA20946230A|rigid:HueTCVxmr3zSUkcN0TtLSJRmqa0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P60510	uniprotkb:Q5SZD4	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	intact:EBI-1774224|ensembl:ENSP00000360240	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:glyl3_human(display_long)|uniprotkb:GLYATL3(gene name)|psi-mi:GLYATL3(display_short)|uniprotkb:C6orf140(gene name synonym)|uniprotkb:"Acyl-CoA:glycine-N-acyltransferase-like protein 3"(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774185|imex:IM-9155-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	refseq:NP_001010904.1|ensembl:ENSG00000203972(gene)|ensembl:ENST00000371197(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0047961"(glycine N-acyltransferase activity)|interpro:IPR010313(Glycine N-acyltransferase)|interpro:IPR013652(Glycine N-acyltransferase, C-terminal)|interpro:IPR015938(Glycine N-acyltransferase, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|reactome:R-HSA-177128|reactome:R-HSA-177135	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rogid:unJ/8vf9MvrsTZo5yvxM4Mvl9aQ9606	intact-crc:D3CC1EA20946230A|rigid:HueTCVxmr3zSUkcN0TtLSJRmqa0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P60510	uniprotkb:Q16204	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	intact:EBI-1045350|uniprotkb:Q15250|uniprotkb:Q6GSG7|ensembl:ENSP00000263102	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:ccdc6_human(display_long)|uniprotkb:Protein H4(gene name synonym)|uniprotkb:Papillary thyroid carcinoma-encoded protein(gene name synonym)|uniprotkb:CCDC6(gene name)|psi-mi:CCDC6(display_short)|uniprotkb:D10S170(gene name synonym)|uniprotkb:TST1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774185|imex:IM-9155-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	refseq:NP_005427.2|ensembl:ENSG00000108091(gene)|ensembl:ENST00000263102(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR019152	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rogid:nPX3jyRnTSavY0tKyxDiVo35n8E9606	intact-crc:D3CC1EA20946230A|rigid:HueTCVxmr3zSUkcN0TtLSJRmqa0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P60510	uniprotkb:P78318	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	intact:EBI-1055954|uniprotkb:Q8TAB2|ensembl:ENSP00000348784|ensembl:ENSP00000363661	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:igbp1_human(display_long)|uniprotkb:IGBP1(gene name)|psi-mi:IGBP1(display_short)|uniprotkb:IBP1(gene name synonym)|uniprotkb:CD79a-binding protein 1(gene name synonym)|uniprotkb:B-cell signal transduction molecule alpha 4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-16(gene name synonym)|uniprotkb:Protein phosphatase 2/4/6 regulatory subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774185|imex:IM-9155-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	refseq:NP_001542.1|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511|mint:P78318|rcsb pdb:4IYP|ensembl:ENSG00000089289(gene)|ensembl:ENST00000342206(transcript)|ensembl:ENST00000356413(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042113"(B cell activation)|refseq:XP_016884978.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rogid:N8w92upYivqH3rjdqNbAcIjDu7I9606	intact-crc:D3CC1EA20946230A|rigid:HueTCVxmr3zSUkcN0TtLSJRmqa0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P60510	uniprotkb:Q9NY27	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	intact:EBI-1048740|uniprotkb:Q2TAJ9|uniprotkb:Q498B8|uniprotkb:Q8WXX6|uniprotkb:A8K1I6|ensembl:ENSP00000349124	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:pp4r2_human(display_long)|uniprotkb:PPP4R2(gene name)|psi-mi:PPP4R2(display_short)|uniprotkb:SBBI57(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774185|imex:IM-9155-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	refseq:NP_777567.1|refseq:NP_001304954.1|refseq:NP_001304955.1|refseq:NP_001304956.1|ensembl:ENSG00000163605(gene)|ensembl:ENST00000356692(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|interpro:IPR015267(Protein phosphatase 4 core regulatory subunit R2)|reactome:R-HSA-5693607	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rogid:oGg4ivn7jMb0bcFGgSdKkqAPhi89606	intact-crc:D3CC1EA20946230A|rigid:HueTCVxmr3zSUkcN0TtLSJRmqa0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P60510	uniprotkb:Q5MIZ7-1	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	intact:EBI-1503007|ensembl:ENSP00000483228	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:q5miz7-1(display_long)|uniprotkb:PPP4R3B(gene name)|psi-mi:PPP4R3B(display_short)|uniprotkb:KIAA1387(gene name synonym)|uniprotkb:PP4R3B(gene name synonym)|uniprotkb:SMEK homolog 2(gene name synonym)|uniprotkb:SMEK2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774185|imex:IM-9155-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	ensembl:ENSG00000275052(gene)|ensembl:ENST00000616407(transcript)|intact:EBI-720732(isoform-parent)	psi-mi:"MI:0469"(intact)	-	isoform-comment:No experimental confirmation available	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rogid:6vE7I6SP48sz9vvWezMslRsltgo9606	intact-crc:D3CC1EA20946230A|rigid:HueTCVxmr3zSUkcN0TtLSJRmqa0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P60510	uniprotkb:P17987	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774185|imex:IM-9155-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606	intact-crc:D3CC1EA20946230A|rigid:HueTCVxmr3zSUkcN0TtLSJRmqa0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P60510	uniprotkb:P50990	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774185|imex:IM-9155-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606	intact-crc:D3CC1EA20946230A|rigid:HueTCVxmr3zSUkcN0TtLSJRmqa0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P60510	uniprotkb:Q6IN85-1	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	intact:EBI-1522297|ensembl:ENSP00000450883	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:q6in85-1(display_long)|uniprotkb:PPP4R3A(gene name)|psi-mi:PPP4R3A(display_short)|uniprotkb:KIAA2010(gene name synonym)|uniprotkb:PP4R3A(gene name synonym)|uniprotkb:SMEK homolog 1(gene name synonym)|uniprotkb:SMEK1(gene name synonym)|uniprotkb:MSTP033(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774185|imex:IM-9155-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	intact:EBI-1055598(isoform-parent)|ensembl:ENSG00000100796(gene)|ensembl:ENST00000554943(transcript)	psi-mi:"MI:0469"(intact)	-	isoform-comment:No experimental confirmation available.	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rogid:/Tc381stK9K9hy3AKtl1yNv9ajA9606	intact-crc:D3CC1EA20946230A|rigid:HueTCVxmr3zSUkcN0TtLSJRmqa0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P60510	uniprotkb:Q8TF05-2	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	intact:EBI-1056280|ensembl:ENSP00000383401	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:q8tf05-2(display_long)|uniprotkb:PPP4R1(gene name)|psi-mi:PPP4R1(display_short)|uniprotkb:MEG1(gene name synonym)|uniprotkb:PP4R1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774185|imex:IM-9155-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	intact:EBI-1056262(pp4r1_human)|ensembl:ENSG00000154845(gene)|ensembl:ENST00000400555(transcript)|uniprotkb:Q8TF05-2(isoform-parent)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rogid:lUULRVjZ3yGQwZTDHbVnuLOO+TM9606	intact-crc:D3CC1EA20946230A|rigid:HueTCVxmr3zSUkcN0TtLSJRmqa0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P60510	uniprotkb:P78371	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774185|imex:IM-9155-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606	intact-crc:D3CC1EA20946230A|rigid:HueTCVxmr3zSUkcN0TtLSJRmqa0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P60510	uniprotkb:P40227	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774185|imex:IM-9155-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	intact-crc:D3CC1EA20946230A|rigid:HueTCVxmr3zSUkcN0TtLSJRmqa0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P60510	uniprotkb:P49368	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774185|imex:IM-9155-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606	intact-crc:D3CC1EA20946230A|rigid:HueTCVxmr3zSUkcN0TtLSJRmqa0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P60510	uniprotkb:Q99832	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774185|imex:IM-9155-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606	intact-crc:D3CC1EA20946230A|rigid:HueTCVxmr3zSUkcN0TtLSJRmqa0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P60510	uniprotkb:P50991	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774185|imex:IM-9155-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606	intact-crc:D3CC1EA20946230A|rigid:HueTCVxmr3zSUkcN0TtLSJRmqa0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P60510	uniprotkb:P48643	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774185|imex:IM-9155-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606	intact-crc:D3CC1EA20946230A|rigid:HueTCVxmr3zSUkcN0TtLSJRmqa0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P60510	uniprotkb:Q6NUP7-1	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	intact:EBI-1774197|ensembl:ENSP00000305924|ensembl:ENSP00000480902	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:q6nup7-1(display_long)|uniprotkb:PPP4R4(gene name)|psi-mi:PPP4R4(display_short)|uniprotkb:KIAA1622(gene name synonym)|uniprotkb:PP4R4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774185|imex:IM-9155-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	intact:EBI-1774189(isoform-parent)|ensembl:ENSG00000119698(gene)|ensembl:ENSG00000278326(gene)|ensembl:ENST00000304338(transcript)|ensembl:ENST00000619905(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Table S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	rogid:xB0nF7qEVTtWnkFQK+JIy15IDQI9606	intact-crc:D3CC1EA20946230A|rigid:HueTCVxmr3zSUkcN0TtLSJRmqa0	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y3A3	uniprotkb:Q59GV6	intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0	intact:EBI-1773535	psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name)	psi-mi:q59gv6_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774238|imex:IM-9155-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1	refseq:NP_001034966.1|interpro:IPR020472|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|go:"GO:0005516"(calmodulin binding)|go:"GO:0016020"(membrane)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary Table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606	rogid:WDFWyHzzBAV9/p99Alv7pgpO4es9606	intact-crc:8EB98FAD4E50DDC4|rigid:8iPHsnqLceow5EwMxGqj3NpA3p4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y3A3	uniprotkb:Q9P289	intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0	intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2	psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name)	psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774238|imex:IM-9155-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1	ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary Table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606	rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606	intact-crc:8EB98FAD4E50DDC4|rigid:8iPHsnqLceow5EwMxGqj3NpA3p4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y3A3	uniprotkb:O43815-2	intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0	intact:EBI-1266294|ensembl:ENSP00000368513	psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name)	psi-mi:o43815-2(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774238|imex:IM-9155-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1	intact:EBI-1046642(strn_human)|ensembl:ENSG00000115808(gene)|ensembl:ENST00000379213(transcript)|uniprotkb:O43815-2(isoform-parent)	psi-mi:"MI:0469"(intact)	-	isoform-comment:No experimental confirmation available.	figure legend:4A and Supplementary Table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606	rogid:6MwK0aY1uqeiOfAmKgQF/j3oNJw9606	intact-crc:8EB98FAD4E50DDC4|rigid:8iPHsnqLceow5EwMxGqj3NpA3p4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y3A3	uniprotkb:P63167	intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0	intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907	psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name)	psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774238|imex:IM-9155-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1	refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary Table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606	rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606	intact-crc:8EB98FAD4E50DDC4|rigid:8iPHsnqLceow5EwMxGqj3NpA3p4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y3A3	uniprotkb:Q9ULQ0-2	intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0	intact:EBI-1774291|ensembl:ENSP00000392393	psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name)	psi-mi:q9ulq0-2(display_long)|uniprotkb:STRIP2(gene name)|psi-mi:STRIP2(display_short)|uniprotkb:FAM40B(gene name synonym)|uniprotkb:KIAA1170(gene name synonym)|uniprotkb:Protein FAM40B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774238|imex:IM-9155-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1	intact:EBI-1774281(isoform-parent)|ensembl:ENSG00000128578(gene)|ensembl:ENST00000435494(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary Table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606	rogid:NQnjWsPWDXjmUifi7F8wgaU7QM89606	intact-crc:8EB98FAD4E50DDC4|rigid:8iPHsnqLceow5EwMxGqj3NpA3p4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y3A3	uniprotkb:Q13033-2	intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0	intact:EBI-1053876|intact:EBI-27830295|ensembl:ENSP00000347909	psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name)	psi-mi:q13033-2(display_long)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774238|imex:IM-9155-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1	intact:EBI-1053857(strn3_human)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000355683(transcript)|uniprotkb:Q13033-2(isoform-parent)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary Table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606	rogid:iNOxFiYQux+p8PBw6q2rZ6W1YRM9606	intact-crc:8EB98FAD4E50DDC4|rigid:8iPHsnqLceow5EwMxGqj3NpA3p4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y3A3	uniprotkb:Q9NVK5-1	intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0	intact:EBI-1524461|ensembl:ENSP00000229395	psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name)	psi-mi:q9nvk5-1(display_long)|uniprotkb:FGFR1OP2(gene name)|psi-mi:FGFR1OP2(display_short)|uniprotkb:HSPC123(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774238|imex:IM-9155-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1	intact:EBI-1104764(isoform-parent)|ensembl:ENSG00000111790(gene)|ensembl:ENST00000229395(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary Table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606	rogid:jXd4sql3WIYvX9V2SbahQYPNMOY9606	intact-crc:8EB98FAD4E50DDC4|rigid:8iPHsnqLceow5EwMxGqj3NpA3p4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y3A3	uniprotkb:Q5VSL9-1	intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0	intact:EBI-1773601|ensembl:ENSP00000358810	psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name)	psi-mi:q5vsl9-1(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774238|imex:IM-9155-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1	intact:EBI-1773588(isoform-parent)|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary Table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606	rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606	intact-crc:8EB98FAD4E50DDC4|rigid:8iPHsnqLceow5EwMxGqj3NpA3p4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y3A3	uniprotkb:A8K3H8	intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0	intact:EBI-1774242	psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name)	psi-mi:a8k3h8_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774238|imex:IM-9155-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1	interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000357(HEAT)|interpro:IPR021133|interpro:IPR031090|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0065003"(protein-containing complex assembly)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary Table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606	rogid:NiSNvoYwrUBCqVJ/u3UM3yU7SAs9606	intact-crc:8EB98FAD4E50DDC4|rigid:8iPHsnqLceow5EwMxGqj3NpA3p4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y3A3	uniprotkb:Q14BN4-1	intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0	intact:EBI-1517328|ensembl:ENSP00000499241	psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name)	psi-mi:q14bn4-1(display_long)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774238|imex:IM-9155-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1	ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|intact:EBI-1043216(isoform-parent)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary Table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606	rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606	intact-crc:8EB98FAD4E50DDC4|rigid:8iPHsnqLceow5EwMxGqj3NpA3p4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y3A3	uniprotkb:Q8WZ74	intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0	intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373	psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name)	psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774238|imex:IM-9155-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1	ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary Table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606	rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606	intact-crc:8EB98FAD4E50DDC4|rigid:8iPHsnqLceow5EwMxGqj3NpA3p4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y3A3	uniprotkb:P62714	intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name)	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774238|imex:IM-9155-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary Table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	intact-crc:8EB98FAD4E50DDC4|rigid:8iPHsnqLceow5EwMxGqj3NpA3p4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y3A3	uniprotkb:P67775	intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name)	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774238|imex:IM-9155-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary Table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	intact-crc:8EB98FAD4E50DDC4|rigid:8iPHsnqLceow5EwMxGqj3NpA3p4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y3A3	uniprotkb:Q9P2B4	intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0	intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277	psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name)	psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774238|imex:IM-9155-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1	refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary Table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606	rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606	intact-crc:8EB98FAD4E50DDC4|rigid:8iPHsnqLceow5EwMxGqj3NpA3p4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9Y3A3	uniprotkb:Q9BRV8-1	intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0	intact:EBI-1773655|ensembl:ENSP00000060969	psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name)	psi-mi:q9brv8-1(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1774238|imex:IM-9155-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1	intact:EBI-1773646(isoform-parent)|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4A and Supplementary Table 6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2014/10/16	rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606	rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606	intact-crc:8EB98FAD4E50DDC4|rigid:8iPHsnqLceow5EwMxGqj3NpA3p4	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q13085-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1497329|ensembl:ENSP00000478547|ensembl:ENSP00000483674	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q13085-1(display_long)|uniprotkb:ACACA(gene name)|psi-mi:ACACA(display_short)|uniprotkb:ACAC(gene name synonym)|uniprotkb:ACC1(gene name synonym)|uniprotkb:ACCA(gene name synonym)|uniprotkb:Acetyl-Coenzyme A carboxylase alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-717681(isoform-parent)|ensembl:ENSG00000275176(gene)|ensembl:ENSG00000278540(gene)|ensembl:ENST00000613687(transcript)|ensembl:ENST00000614428(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:P9d0QlkoP1zrBdF1WOrK68ueGng9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P60510	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P62979	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-357375|ensembl:ENSP00000272317|ensembl:ENSP00000383981|ensembl:ENSP00000385659|uniprotkb:P14798|uniprotkb:Q6LBL4|uniprotkb:Q9BQ77|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62988|uniprotkb:Q29120|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rs27a_human(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:Ubiquitin carboxyl extension protein 80(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8854050|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9633012|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975163|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-977225|reactome:R-HSA-983168|reactome:R-HSA-975144|ensembl:ENSG00000143947(gene)|ensembl:ENST00000272317(transcript)|ensembl:ENST00000402285(transcript)|ensembl:ENST00000404735(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0010008"(endosome membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038582|mint:P62979|rcsb pdb:2KHW|rcsb pdb:2KOX|rcsb pdb:2KTF|rcsb pdb:2KWU|rcsb pdb:2KWV|rcsb pdb:2L0F|rcsb pdb:2L0T|rcsb pdb:2XK5|rcsb pdb:3AXC|rcsb pdb:3I3T|rcsb pdb:3K9P|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3NHE|rcsb pdb:3NOB|rcsb pdb:3NS8|rcsb pdb:3PHD|rcsb pdb:3PHW|rcsb pdb:3TBL|rcsb pdb:3VDZ|rcsb pdb:4R62|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:5A2Q|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:5AJ0|rcsb pdb:6IP8|rcsb pdb:6J99|rcsb pdb:5FLX|rcsb pdb:6KFP|rcsb pdb:5LKS|rcsb pdb:6KG6|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SQO|rcsb pdb:5T2C|rcsb pdb:5WVO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:5YDK|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6DC6|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:7K5I|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZXF|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|rcsb pdb:6ZXG|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|rcsb pdb:6ZXH|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-1799339|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|rcsb pdb:7A09|rcsb pdb:7BWD|reactome:R-HSA-192823|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-2565942|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-211733|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-2122947|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-2122948|reactome:R-HSA-4641258|reactome:R-HSA-2173788|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-2173791|reactome:R-HSA-5357905|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-2559585|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656169|reactome:R-HSA-5656121|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6791226|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|refseq:NP_001129064.1|refseq:NP_001170884.1|refseq:NP_002945.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:2LSJafy6vjKHYZcZVx8zZaOXRis9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P04264	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-298429|uniprotkb:Q14720|uniprotkb:Q6GSJ0|uniprotkb:B2RA01|uniprotkb:Q9H298|ensembl:ENSP00000252244|uniprotkb:P85925|uniprotkb:P86104	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:k2c1_human(display_long)|uniprotkb:KRT1(gene name)|psi-mi:KRT1(display_short)|uniprotkb:KRTA(gene name synonym)|uniprotkb:Keratin-1(gene name synonym)|uniprotkb:Cytokeratin-1(gene name synonym)|uniprotkb:67 kDa cytokeratin(gene name synonym)|uniprotkb:Hair alpha protein(gene name synonym)|uniprotkb:Type-II keratin Kb1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_006112.3|ensembl:ENSG00000167768(gene)|ensembl:ENST00000252244(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042730"(fibrinolysis)|go:"GO:0045095"(keratin filament)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR032449|interpro:IPR039008|mint:P04264|rcsb pdb:4ZRY|rcsb pdb:6E2J|rcsb pdb:6UUI|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:TeAC3i2hWTS2lgXT0i4agp9nv349606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P51610-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-396188|ensembl:ENSP00000309555	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:p51610-1(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:HFC1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-396176(hcfc1_human)|ensembl:ENSG00000172534(gene)|ensembl:ENST00000310441(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P31151	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-357520|uniprotkb:Q6FGE3|uniprotkb:Q5SY67|uniprotkb:Q9H1E2|ensembl:ENSP00000357711|ensembl:ENSP00000357712	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:s10a7_human(display_long)|uniprotkb:S100A7(gene name)|psi-mi:S100A7(display_short)|uniprotkb:PSOR1(gene name synonym)|uniprotkb:S100A7C(gene name synonym)|uniprotkb:S100 calcium-binding protein A7(gene name synonym)|uniprotkb:Psoriasin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000143556(gene)|ensembl:ENST00000368722(transcript)|ensembl:ENST00000368723(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045087"(innate immune response)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051238"(sequestering of metal ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071624"(positive regulation of granulocyte chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028477|interpro:IPR034325|mint:P31151|rcsb pdb:1PSR|rcsb pdb:2PSR|rcsb pdb:2WND|rcsb pdb:2WOR|rcsb pdb:2WOS|rcsb pdb:3PSR|rcsb pdb:4AQJ|reactome:R-HSA-6798695|reactome:R-HSA-6799990|refseq:NP_002954.2	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:/v8+XQ7rCMTYzq9k/KqjcSm/G0A9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q96E39	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-2211204|ensembl:ENSP00000318415|ensembl:ENSP00000446099|ensembl:ENSP00000498248	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rmxl1_human(display_long)|uniprotkb:RBMXL1(gene name)|psi-mi:RBMXL1(display_short)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G-like 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001156008.1|refseq:NP_062556.2|ensembl:ENSG00000213516(gene)|ensembl:ENST00000321792(transcript)|ensembl:ENST00000399794(transcript)|ensembl:ENST00000652648(transcript)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:J2BrUHGcladV+yTecfJVfljlFz89606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P49411	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P62263	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-352783|ensembl:ENSP00000311028|ensembl:ENSP00000385425|uniprotkb:P06366|uniprotkb:Q5BJI0|uniprotkb:B2R5G5|uniprotkb:D3DQG5|ensembl:ENSP00000385958|ensembl:ENSP00000428509	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rs14_human(display_long)|uniprotkb:RPS14(gene name)|psi-mi:RPS14(display_short)|uniprotkb:Small ribosomal subunit protein uS11(gene name synonym)|uniprotkb:PRO2640(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000164587(gene)|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001020242.1|refseq:NP_005608.1|refseq:NP_001020241.1|ensembl:ENST00000312037(transcript)|ensembl:ENST00000401695(transcript)|ensembl:ENST00000407193(transcript)|ensembl:ENST00000521466(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR001971(Ribosomal protein S11)|interpro:IPR018102|interpro:IPR036967|mint:P62263|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZXD	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:ee3bJ5JYFaZXyCCRG9Wooopyz2o9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P05412	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-852823|uniprotkb:Q96G93|uniprotkb:Q6FHM7|ensembl:ENSP00000360266|ensembl:ENSP00000503132	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:jun_human(display_long)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short)|uniprotkb:Activator protein 1(gene name synonym)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)|uniprotkb:p39(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_002219.1|ensembl:ENSP00000360266|ensembl:ENSP00000503132|dip:DIP-5961N|ensembl:ENSG00000177606(gene)|ensembl:ENST00000371222(transcript)|ensembl:ENST00000678696(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009314"(response to radiation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051365"(cellular response to potassium ion starvation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR015558(c-Jun Transcription Factor)|mint:P05412|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1JNM|rcsb pdb:1JUN|rcsb pdb:1S9K|rcsb pdb:1T2K|rcsb pdb:5FV8|rcsb pdb:5T01|rcsb pdb:6Y3V|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-6796648|reactome:R-HSA-8862803|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9673324	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:zAVYwedHKKdvPPGttBP4XZkbCXA9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P04259	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-740907|ensembl:ENSP00000252252|uniprotkb:P48669	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:k2c6b_human(display_long)|uniprotkb:Cytokeratin-6B(gene name synonym)|uniprotkb:Keratin-6B(gene name synonym)|uniprotkb:KRT6B(gene name)|psi-mi:KRT6B(display_short)|uniprotkb:K6B(gene name synonym)|uniprotkb:KRTL1(gene name synonym)|uniprotkb:Type-II keratin Kb10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_005546.2|ensembl:ENSG00000185479(gene)|ensembl:ENST00000252252(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0007398"(ectoderm development)|go:"GO:0045095"(keratin filament)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P04259|reactome:R-HSA-6805567|reactome:R-HSA-6809371	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:lFuNGZdQm4pftz53qbflLTyyAaQ9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q8N163-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1021318|ensembl:ENSP00000310670|ensembl:ENSP00000373930	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q8n163-1(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-355410(q8n163_human)|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P11021	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q7Z2W4-2	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-922559|ensembl:ENSP00000419855	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q7z2w4-2(display_long)|uniprotkb:ZC3HAV1(gene name)|psi-mi:ZC3HAV1(display_short)|uniprotkb:ZC3HDC2(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger antiviral protein(gene name synonym)|uniprotkb:PRO1677(orf name)|uniprotkb:ZAPS(isoform synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 13(gene name synonym)|uniprotkb:Inactive Poly [ADP-ribose] polymerase 13(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-922540(zcc2_human)|ensembl:ENSG00000105939(gene)|ensembl:ENST00000471652(transcript)|uniprotkb:Q7Z2W4-2(isoform-parent)	psi-mi:"MI:0469"(intact)	-	isoform-comment:No experimental confirmation available.	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:iYC6SVjVUbaBJ7RnzFluOsH9UAQ9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q00839-2	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-351143|ensembl:ENSP00000393151	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q00839-2(display_long)|uniprotkb:HNRNPU(gene name)|psi-mi:HNRNPU(display_short)|uniprotkb:HNRPU(gene name synonym)|uniprotkb:SAFA(gene name synonym)|uniprotkb:U21.1(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:pp120(gene name synonym)|uniprotkb:C1orf199(gene name synonym)|uniprotkb:GRIP120(gene name synonym)|uniprotkb:Nuclear p120 ribonucleoprotein(gene name synonym)|uniprotkb:Scaffold-attachment factor A(gene name synonym)|uniprotkb:Short(isoform synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-351126(hnrpu_human)|ensembl:ENSG00000153187(gene)|ensembl:ENST00000444376(transcript)|uniprotkb:Q00839-2(isoform-parent)	psi-mi:"MI:0469"(intact)	-	isoform-comment:Contains a N6-acetyllysine at position 215.	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:ZldKJyn+DVBGTl23VqnG4lcmk7c9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P62753	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356625|uniprotkb:P08227|uniprotkb:P10660|uniprotkb:Q4VBY7|uniprotkb:Q8N6Z7|ensembl:ENSP00000369757	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rs6_human(display_long)|uniprotkb:RPS6(gene name)|psi-mi:RPS6(display_short)|uniprotkb:Phosphoprotein NP33(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS6(gene name synonym)|uniprotkb:OK/SW-cl.2(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001001.2|reactome:R-HSA-166208|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR014401(Ribosomal protein S6, eukaryotic)|interpro:IPR018282|mint:P62753|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6F4P|rcsb pdb:6F4Q|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|ensembl:ENSG00000137154(gene)|ensembl:ENST00000380394(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001890"(placenta development)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022605"(mammalian oogenesis stage)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030425"(dendrite)|go:"GO:0031929"(TOR signaling)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048821"(erythrocyte development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001377(Ribosomal protein S6e)|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|dip:DIP-31507N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:beDuXCIqL99V9JlVfpzx7MdpH689606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q13263-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-413356|ensembl:ENSP00000253024	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q13263-1(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-78139(tif1b_human)|ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:O00571	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q14244-3	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-2211285|ensembl:ENSP00000483511	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q14244-3(display_long)|uniprotkb:MAP7(gene name)|psi-mi:MAP7(display_short)|uniprotkb:Epithelial microtubule-associated protein of 115 kDa(gene name synonym)|uniprotkb:Microtubule-associated protein 7(gene name synonym)|uniprotkb:E-MAP-115-95(isoform synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-2211064(isoform-parent)|ensembl:ENSG00000135525(gene)|ensembl:ENST00000616617(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:miqR4QlTDQOluJNI+Wc7A2QFhSE9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P68371	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q14289	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-298640|uniprotkb:Q13475|uniprotkb:Q14290|uniprotkb:Q16709|intact:EBI-2211226|uniprotkb:Q6PID4|ensembl:ENSP00000332816|ensembl:ENSP00000380638|uniprotkb:D3DST0	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:fak2_human(display_long)|uniprotkb:PTK2B(gene name)|psi-mi:PTK2B(display_short)|uniprotkb:FAK2(gene name synonym)|uniprotkb:PYK2(gene name synonym)|uniprotkb:RAFTK(gene name synonym)|uniprotkb:Focal adhesion kinase 2(gene name synonym)|uniprotkb:Proline-rich tyrosine kinase 2(gene name synonym)|uniprotkb:Cell adhesion kinase beta(gene name synonym)|uniprotkb:Calcium-dependent tyrosine kinase(gene name synonym)|uniprotkb:Related adhesion focal tyrosine kinase(gene name synonym)|uniprotkb:Calcium-regulated non-receptor proline-rich tyrosine kinase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_004094.3|refseq:NP_775266.1|refseq:NP_775267.1|refseq:NP_775268.1|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032960"(regulation of inositol trisphosphate biosynthetic process)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051591"(response to cAMP)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097440"(apical dendrite)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000058"(regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR020635|interpro:IPR029071|interpro:IPR030610|interpro:IPR035963|interpro:IPR036137|interpro:IPR041390|interpro:IPR041784|rcsb pdb:2FO6|rcsb pdb:2LK4|rcsb pdb:3CC6|rcsb pdb:3ET7|rcsb pdb:3FZO|rcsb pdb:3FZP|rcsb pdb:3FZR|rcsb pdb:3FZS|rcsb pdb:3FZT|rcsb pdb:3GM1|rcsb pdb:3GM2|rcsb pdb:3GM3|rcsb pdb:3H3C|rcsb pdb:3U3F|rcsb pdb:4EKU|rcsb pdb:4H1J|rcsb pdb:4H1M|rcsb pdb:4R32|rcsb pdb:4XEF|rcsb pdb:4XEK|rcsb pdb:4XEV|rcsb pdb:5TO8|rcsb pdb:5TOB|rcsb pdb:6LF3|reactome:R-HSA-391160|reactome:R-HSA-4420097|reactome:R-HSA-9020558|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043423"(3-phosphoinositide-dependent protein kinase binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044297"(cell body)|go:"GO:0045453"(bone resorption)|go:"GO:0045471"(response to ethanol)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000538"(positive regulation of B cell chemotaxis)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR005189(Focal adhesion targeting region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009725"(response to hormone)|go:"GO:0009749"(response to glucose)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010656"(negative regulation of muscle cell apoptotic process)|go:"GO:0010752"(regulation of cGMP-mediated signaling)|go:"GO:0010758"(regulation of macrophage chemotaxis)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|ensembl:ENSG00000120899(gene)|ensembl:ENST00000346049(transcript)|ensembl:ENST00000397501(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001525"(angiogenesis)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0002250"(adaptive immune response)|refseq:XP_011542743.1|refseq:XP_005273504.1|refseq:XP_016868703.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:rpqjaDBbtx7BK+JiIR/sBlyPLvY9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P42677	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356336|ensembl:ENSP00000499044|uniprotkb:Q5T4L6	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rs27_human(display_long)|uniprotkb:RPS27(gene name)|psi-mi:RPS27(display_short)|uniprotkb:MPS1(gene name synonym)|uniprotkb:Metallopan-stimulin 1(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS27(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001021.1|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|ensembl:ENSG00000177954(gene)|ensembl:ENST00000651669(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:P42677|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-141444|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-2500257|rcsb pdb:6OM7|reactome:R-HSA-5663220|reactome:R-HSA-6791226|reactome:R-HSA-68877|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-9648025|reactome:R-HSA-975956|reactome:R-HSA-975957|dip:DIP-44182N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:OA5IWAJDBpY5FFdVnun7Sq/jI7g9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P62913-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-354391|uniprotkb:P39026-1|ensembl:ENSP00000496250	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:p62913-1(display_long)|uniprotkb:RPL11(gene name)|psi-mi:RPL11(display_short)|uniprotkb:CLL-associated antigen KW-12(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-354380(rpl11_human)|ensembl:ENSG00000142676(gene)|ensembl:ENST00000643754(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:xt8XhDkfQPoH4DIPr0gC+ll766Q9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q15717	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-374260|uniprotkb:Q9BTT1|ensembl:ENSP00000385269|ensembl:ENSP00000472197|intact:EBI-6190219|uniprotkb:B4DVB8|uniprotkb:Q53XN6	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:elav1_human(display_long)|uniprotkb:ELAVL1(gene name)|psi-mi:ELAVL1(display_short)|uniprotkb:HUR(gene name synonym)|uniprotkb:Hu-antigen R(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	go:"GO:0006606"(protein import into nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035198"(miRNA binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|ensembl:ENSG00000066044(gene)|ensembl:ENST00000407627(transcript)|ensembl:ENST00000596459(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|refseq:NP_001410.2|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR034996|interpro:IPR035979|mint:Q15717|rcsb pdb:3HI9|rcsb pdb:4ED5|rcsb pdb:4EGL|rcsb pdb:4FXV|rcsb pdb:5SZW|rcsb pdb:6G2K|rcsb pdb:6GC5|rcsb pdb:6GD1|rcsb pdb:6GD2|rcsb pdb:6GD3|reactome:R-HSA-450520|reactome:R-HSA-72163|dip:DIP-31291N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:PciL5KuvP+2aUUv9cv7gWScgbw89606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P02538	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-702198|uniprotkb:P48667|uniprotkb:Q08AR4|uniprotkb:Q6NT67|uniprotkb:Q96CL4|uniprotkb:A4QPC1|ensembl:ENSP00000369317	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:k2c6a_human(display_long)|uniprotkb:Cytokeratin-6A(gene name synonym)|uniprotkb:Keratin-6A(gene name synonym)|uniprotkb:Cytokeratin-6D(gene name synonym)|uniprotkb:KRT6A(gene name)|psi-mi:KRT6A(display_short)|uniprotkb:K6A(gene name synonym)|uniprotkb:KRT6D(gene name synonym)|uniprotkb:Type-II keratin Kb6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_005545.1|dip:DIP-533N|ensembl:ENSG00000205420(gene)|ensembl:ENST00000330722(transcript)|go:"GO:0001899"(negative regulation of cytolysis by symbiont of host cells)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0042060"(wound healing)|go:"GO:0045095"(keratin filament)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051838"(cytolysis by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000536"(negative regulation of entry of bacterium into host cell)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P02538|rcsb pdb:5KI0|reactome:R-HSA-6805567|reactome:R-HSA-6809371	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:feIxUFTSMnjattUda5vdGhiL9H89606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q02413	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1045757|intact:EBI-28968615|ensembl:ENSP00000257192|uniprotkb:B7Z845	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:dsg1_human(display_long)|uniprotkb:CDHF4(gene name synonym)|uniprotkb:Desmosomal glycoprotein 1(gene name synonym)|uniprotkb:Pemphigus foliaceus antigen(gene name synonym)|uniprotkb:DSG1(gene name)|psi-mi:DSG1(display_short)|uniprotkb:Cadherin family member 4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSP00000257192|refseq:NP_001933.2|ensembl:ENSG00000134760(gene)|ensembl:ENST00000257192(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0030057"(desmosome)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR009123(Desmoglein)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|mint:Q02413|reactome:R-HSA-351906|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9696264|reactome:R-HSA-9696270	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:CiRFIJ9IWOol9bQpLJPxH8JArtE9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q96RF1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-2211196	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q96rf1_human(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	interpro:IPR044713|go:"GO:0006457"(protein folding)|go:"GO:0030544"(Hsp70 protein binding)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:m3wiJamjfqpEe3yxy+j/8W5znFs9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P15924-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-355054|ensembl:ENSP00000369129	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:p15924-1(display_long)|uniprotkb:DP1(isoform synonym)|uniprotkb:DSP(gene name)|psi-mi:DSP(display_short)|uniprotkb:250/210 kDa paraneoplastic pemphigus antigen(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-355041(desp_human)|ensembl:ENSG00000096696(gene)|ensembl:ENST00000379802(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:enapEqSoyTSLfPEQUAopkGpdxbo9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P05109	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-355281|uniprotkb:Q5SY70|uniprotkb:Q9UC92|uniprotkb:Q9UCJ0|uniprotkb:A8K5L3|uniprotkb:Q9UC84|uniprotkb:Q9UCM6|uniprotkb:D3DV37|ensembl:ENSP00000357721|ensembl:ENSP00000357722	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:s10a8_human(display_long)|uniprotkb:S100A8(gene name)|psi-mi:S100A8(display_short)|uniprotkb:CAGA(gene name synonym)|uniprotkb:MRP8(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:S100 calcium-binding protein A8(gene name synonym)|uniprotkb:Calgranulin-A(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 8(gene name synonym)|uniprotkb:Cystic fibrosis antigen(gene name synonym)|uniprotkb:Leukocyte L1 complex light chain(gene name synonym)|uniprotkb:Calprotectin L1L subunit(gene name synonym)|uniprotkb:Urinary stone protein band A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001306126.1|refseq:NP_001306127.1|refseq:NP_001306130.1|refseq:NP_002955.2|go:"GO:0042060"(wound healing)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045471"(response to ethanol)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028474|go:"GO:0035662"(Toll-like receptor 4 binding)|mint:P05109|rcsb pdb:1MR8|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5HLO|rcsb pdb:5HLV|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENST00000368732(transcript)|ensembl:ENST00000368733(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002526"(acute inflammatory response)|ensembl:ENSG00000143546(gene)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002793"(positive regulation of peptide secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010043"(response to zinc ion)|go:"GO:0014002"(astrocyte development)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|dip:DIP-1165N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:3Okfhj8fxclZ0Uo/Fa1Z89qC8Ec9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P14923	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-702484|uniprotkb:Q15093|intact:EBI-988999|intact:EBI-744449|uniprotkb:Q9HCX9|uniprotkb:Q15151|uniprotkb:Q7L3S5|uniprotkb:Q86W21|uniprotkb:Q9BWC4|ensembl:ENSP00000311113|ensembl:ENSP00000377507|ensembl:ENSP00000377508	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:plak_human(display_long)|uniprotkb:JUP(gene name)|psi-mi:JUP(display_short)|uniprotkb:DP3(gene name synonym)|uniprotkb:CTNNG(gene name synonym)|uniprotkb:Desmoplakin-3(gene name synonym)|uniprotkb:Desmoplakin III(gene name synonym)|uniprotkb:Catenin gamma(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_002221.1|refseq:NP_068831.1|refseq:XP_011523055.1|refseq:XP_011523057.1|refseq:XP_011523058.1|refseq:XP_011523059.1|refseq:XP_011523060.1|refseq:XP_006721936.1|refseq:XP_006721937.1|refseq:XP_006721938.1|refseq:XP_006721941.1|refseq:XP_016880079.1|dip:DIP-36235N|ensembl:ENSG00000173801(gene)|ensembl:ENST00000310706(transcript)|ensembl:ENST00000393930(transcript)|ensembl:ENST00000393931(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002159"(desmosome assembly)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030057"(desmosome)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043588"(skin development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071603"(endothelial cell-cell adhesion)|go:"GO:0071665"(gamma-catenin-TCF7L2 complex)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR030461|mint:P14923|rcsb pdb:3IFQ|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:qOBUlbifyKUk1xF0Zr9jZPkZozc9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:O14654	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356594|ensembl:ENSP00000505547	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P61978-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-431928|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244-1	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:p61978-1(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000165119(gene)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|intact:EBI-304185(hnrpk_human)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P62701	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-354303|uniprotkb:P12631|uniprotkb:P12750|uniprotkb:P27576|uniprotkb:Q14727|uniprotkb:P55831|uniprotkb:Q6IPY4|ensembl:ENSP00000362744	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rs4x_human(display_long)|uniprotkb:RPS4X(gene name)|psi-mi:RPS4X(display_short)|uniprotkb:CCG2(gene name synonym)|uniprotkb:RPS4(gene name synonym)|uniprotkb:SCAR(gene name synonym)|uniprotkb:Single copy abundant mRNA protein(gene name synonym)|uniprotkb:SCR10(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_000998.1|rcsb pdb:6OLI|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000198034(gene)|ensembl:ENST00000316084(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000876(Ribosomal protein S4e)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005824(KOW)|interpro:IPR013843(Ribosomal protein S4e, N-terminal)|interpro:IPR013845(Ribosomal protein S4e, central)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR018199|interpro:IPR032277|interpro:IPR036986|interpro:IPR038237|interpro:IPR041982|mint:P62701|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|go:"GO:0045727"(positive regulation of translation)|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:2ZuLXqBSDkK0CtN3mnIDoFAR8yI9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q8N532	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-357335	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q8n532_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|interpro:IPR002452(Alpha tubulin)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR000217(Tubulin)|interpro:IPR018316|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR036525|interpro:IPR037103	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:bAUct6Os2AwoMFNTPDsCtJomBno9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P60660	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-300817|uniprotkb:P16475|uniprotkb:P24572|uniprotkb:P24573|uniprotkb:Q12790|ensembl:ENSP00000446955|ensembl:ENSP00000448101|uniprotkb:Q6IAZ0|uniprotkb:Q6IPY5|uniprotkb:Q561V9	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:myl6_human(display_long)|uniprotkb:MYL6(gene name)|psi-mi:MYL6(display_short)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6(gene name synonym)|uniprotkb:Myosin light chain alkali 3(gene name synonym)|uniprotkb:Myosin light chain 3(gene name synonym)|uniprotkb:17 kDa myosin light chain(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000092841(gene)|ensembl:ENST00000548293(transcript)|ensembl:ENST00000550697(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P60660|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:NP_066299.2|refseq:NP_524147.2	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:LhE3NUqcuHlOla13C0vjnFZfzy89606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P62829	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-353303|uniprotkb:P23131|uniprotkb:Q3SWV7|uniprotkb:P24048|uniprotkb:Q29246|uniprotkb:Q6P5S1|ensembl:ENSP00000377865|ensembl:ENSP00000420311	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rl23_human(display_long)|uniprotkb:RPL23(gene name)|psi-mi:RPL23(display_short)|uniprotkb:60S ribosomal protein L17(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL14(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|reactome:R-HSA-9010553|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|refseq:NP_000969.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000218(Ribosomal protein L14b/L23e)|interpro:IPR019972|interpro:IPR036853|mint:P62829|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|ensembl:ENSG00000125691(gene)|ensembl:ENST00000394332(transcript)|ensembl:ENST00000479035(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005730"(nucleolus)|dip:DIP-33156N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:TiSVU2W4+lkwf12eb4+vG6IFlZA9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P81605	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P02533	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-702178|uniprotkb:Q14715|uniprotkb:Q53XY3|uniprotkb:Q9BUE3|uniprotkb:Q9UBN2|uniprotkb:Q9UBN3|uniprotkb:Q9UCY4|ensembl:ENSP00000167586	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:k1c14_human(display_long)|uniprotkb:Cytokeratin-14(gene name synonym)|uniprotkb:KRT14(gene name)|psi-mi:KRT14(display_short)|uniprotkb:Keratin-14(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_000517.2|dip:DIP-33874N|ensembl:ENSG00000186847(gene)|ensembl:ENST00000167586(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0007568"(aging)|go:"GO:0008544"(epidermis development)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042633"(hair cycle)|go:"GO:0045095"(keratin filament)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0045178"(basal part of cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990254"(keratin filament binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P02533|rcsb pdb:3TNU|rcsb pdb:6JFV|reactome:R-HSA-446107|reactome:R-HSA-6805567|reactome:R-HSA-6809371	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:IO1k6S8FB65jQr4GNwhKuxZ1ohg9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P10412	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-358163|uniprotkb:Q4VB25|ensembl:ENSP00000307705	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:h14_human(display_long)|uniprotkb:H1-4(gene name)|psi-mi:H1-4(display_short)|uniprotkb:H1F4(gene name synonym)|uniprotkb:HIST1H1E(gene name synonym)|uniprotkb:Histone H1b(gene name synonym)|uniprotkb:Histone H1s-4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_005312.1|rcsb pdb:6H8P|rcsb pdb:7K5Y|rcsb pdb:7K63|go:"GO:0032564"(dATP binding)|go:"GO:0043531"(ADP binding)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P10412|rcsb pdb:3TZD|rcsb pdb:5JJZ|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000168298(gene)|ensembl:ENST00000304218(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0000792"(heterochromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016208"(AMP binding)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:yT8wBbspLLR8G3DrgpFeWEOPgac9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P07437	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q6NZY4-2	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1263072|ensembl:ENSP00000438993|ensembl:ENSP00000441423	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q6nzy4-2(display_long)|uniprotkb:ZCCHC8(gene name)|psi-mi:ZCCHC8(display_short)|uniprotkb:TRAMP-like complex RNA-binding factor ZCCHC8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-1263058(zchc8_human)|ensembl:ENSG00000033030(gene)|ensembl:ENST00000536306(transcript)|ensembl:ENST00000543897(transcript)	psi-mi:"MI:0469"(intact)	-	isoform-comment:No experimental confirmation available.	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:jvdaPe814cLpLyL7r8CAd4Q0Jgg9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P42285	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-347612|uniprotkb:Q2M386|uniprotkb:Q6MZZ8|uniprotkb:Q6P170|uniprotkb:Q8N5R0|uniprotkb:Q8TAG2|ensembl:ENSP00000230640	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:mtrex_human(display_long)|uniprotkb:MTREX(gene name)|psi-mi:MTREX(display_short)|uniprotkb:DOB1(gene name synonym)|uniprotkb:KIAA0052(gene name synonym)|uniprotkb:MTR4(gene name synonym)|uniprotkb:SKIV2L2(gene name synonym)|uniprotkb:Superkiller viralicidic activity 2-like 2(gene name synonym)|uniprotkb:TRAMP-like complex helicase(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DOB1(gene name synonym)|uniprotkb:ATP-dependent RNA helicase SKIV2L2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_056175.3|ensembl:ENSG00000039123(gene)|ensembl:ENST00000230640(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0031499"(TRAMP complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|mint:P42285|rcsb pdb:6C90|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6IEG|rcsb pdb:6IEH|rcsb pdb:6RO1|reactome:R-HSA-6791226|reactome:R-HSA-72163	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:bQdFDddFhetSp+CJ1S7Q5cm+g0k9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P35527	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356382|uniprotkb:O00109|uniprotkb:Q0IJ47|uniprotkb:Q14665|ensembl:ENSP00000246662	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:k1c9_human(display_long)|uniprotkb:KRT9(gene name)|psi-mi:KRT9(display_short)|uniprotkb:Keratin-9(gene name synonym)|uniprotkb:Cytokeratin-9(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_000217.2|ensembl:ENSG00000171403(gene)|ensembl:ENST00000246662(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0043588"(skin development)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P35527|reactome:R-HSA-6805567|reactome:R-HSA-6809371	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:m4EXfxbK2t1/EmI04YODKTJ02Zw9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P46940	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-297509|ensembl:ENSP00000268182|uniprotkb:A7MBM3	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:iqga1_human(display_long)|uniprotkb:IQGAP1(gene name)|psi-mi:IQGAP1(display_short)|uniprotkb:KIAA0051(gene name synonym)|uniprotkb:p195(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000140575(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|ensembl:ENST00000268182(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036057"(slit diaphragm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000048(IQ calmodulin-binding region)|go:"GO:0030667"(secretory granule membrane)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR027417|interpro:IPR036872|mint:P46940|rcsb pdb:1X0H|rcsb pdb:2RR8|rcsb pdb:3FAY|rcsb pdb:3I6X|rcsb pdb:5L0O|reactome:R-HSA-373753|reactome:R-HSA-381676|reactome:R-HSA-5626467|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:NP_003861.1|dip:DIP-32597N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:nXO2Z6Qn8EQGfziT8dnWz1pbK/w9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P11142-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-351908|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:p11142-1(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-351896(hsp7c_human)|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P22392	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-713693|ensembl:ENSP00000376886|ensembl:ENSP00000421064|ensembl:ENSP00000425581|ensembl:ENSP00000426901|ensembl:ENSP00000426976|uniprotkb:A8MWA3|uniprotkb:Q1WM23|uniprotkb:Q6LCT6	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:ndkb_human(display_long)|uniprotkb:nm23-H2(gene name synonym)|uniprotkb:C-myc purine-binding transcription factor PUF(gene name synonym)|uniprotkb:NME2(gene name)|psi-mi:NME2(display_short)|uniprotkb:NM23B(gene name synonym)|uniprotkb:Histidine protein kinase NDKB(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000243678(gene)|ensembl:ENST00000393190(transcript)|ensembl:ENST00000503064(transcript)|ensembl:ENST00000512737(transcript)|ensembl:ENST00000513177(transcript)|ensembl:ENST00000514264(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_001018146.1|refseq:NP_001018147.1|refseq:NP_001018148.1|refseq:NP_001018149.1|refseq:NP_002503.1|dip:DIP-50179N|go:"GO:0005882"(intermediate filament)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0060416"(response to growth hormone)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071944"(cell periphery)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850|mint:P22392|rcsb pdb:1NSK|rcsb pdb:1NUE|rcsb pdb:3BBB|rcsb pdb:3BBC|rcsb pdb:3BBF|reactome:R-HSA-499943|reactome:R-HSA-6798695|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019003"(GDP binding)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045682"(regulation of epidermis development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:GHHfoXOuc25KIJJqiW9r+OWm5Kk9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q06830	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-353193|ensembl:ENSP00000262746|ensembl:ENSP00000361152|ensembl:ENSP00000389047|ensembl:ENSP00000407034|ensembl:ENSP00000503140|uniprotkb:P35703|uniprotkb:Q2V576|uniprotkb:Q5T154|uniprotkb:Q5T155|uniprotkb:B5BU26|uniprotkb:D3DPZ8	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:prdx1_human(display_long)|uniprotkb:PRDX1(gene name)|psi-mi:PRDX1(display_short)|uniprotkb:PAGA(gene name synonym)|uniprotkb:PAGB(gene name synonym)|uniprotkb:TDPX2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Proliferation-associated gene protein(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor A(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000117450(gene)|ensembl:ENST00000262746(transcript)|ensembl:ENST00000319248(transcript)|ensembl:ENST00000424390(transcript)|ensembl:ENST00000447184(transcript)|ensembl:ENST00000676549(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003723"(RNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042470"(melanosome)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q06830|rcsb pdb:2RII|rcsb pdb:3HY2|rcsb pdb:4XCS|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803|refseq:NP_001189360.1|refseq:NP_002565.1|refseq:NP_859047.1|refseq:NP_859048.1|dip:DIP-33152N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:ZM5ZXF900izH81QVqgd2+opwMrs9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P38646	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P11498	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-2211322|uniprotkb:Q16705|uniprotkb:B4DN00|ensembl:ENSP00000377527|ensembl:ENSP00000377530|ensembl:ENSP00000377532|ensembl:ENSP00000435905|ensembl:ENSP00000498302|ensembl:ENSP00000498406|ensembl:ENSP00000498994	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:pyc_human(display_long)|uniprotkb:PC(gene name)|psi-mi:PC(display_short)|uniprotkb:Pyruvic carboxylase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:XP_011543388.1|refseq:XP_016873357.1|refseq:XP_016873358.1|refseq:XP_016873359.1|refseq:XP_016873360.1|refseq:XP_016873361.1|refseq:NP_000911.2|refseq:NP_001035806.1|refseq:NP_071504.2|refseq:XP_005274088.1|refseq:XP_005274089.1|refseq:XP_006718641.1|dip:DIP-46372N|ensembl:ENSG00000173599(gene)|ensembl:ENST00000393955(transcript)|ensembl:ENST00000393958(transcript)|ensembl:ENST00000393960(transcript)|ensembl:ENST00000529047(transcript)|ensembl:ENST00000651036(transcript)|ensembl:ENST00000651854(transcript)|ensembl:ENST00000652125(transcript)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0009374"(biotin binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0042802"(identical protein binding)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR001882(Biotin-binding site)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|mint:P11498|rcsb pdb:3BG3|rcsb pdb:3BG9|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70263	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:0xXv1wxe0AC1EO7wxSDVhBpHCUU9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q9HCC0-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-2211442|ensembl:ENSP00000343657	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q9hcc0-1(display_long)|uniprotkb:MCCC2(gene name)|psi-mi:MCCC2(display_short)|uniprotkb:MCCB(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase 2(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta"(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-2211296(isoform-parent)|ensembl:ENSG00000131844(gene)|ensembl:ENST00000340941(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:5NkqDKqdX1wHsbqXW7v5+/Gld109606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q9H0K1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1181664|uniprotkb:A8K5B8|uniprotkb:O94878|uniprotkb:Q17RV0|uniprotkb:Q6AZE2|uniprotkb:Q76N03|uniprotkb:Q8NCV7|uniprotkb:Q96CZ8|uniprotkb:B0YJ94|ensembl:ENSP00000305976	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:sik2_human(display_long)|uniprotkb:SIK2(gene name)|psi-mi:SIK2(display_short)|uniprotkb:Qin-induced kinase(gene name synonym)|uniprotkb:SNF1LK2(gene name synonym)|uniprotkb:KIAA0781(gene name synonym)|uniprotkb:QIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SNF1-like kinase 2(gene name synonym)|uniprotkb:Salt-inducible kinase 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_056006.1|ensembl:ENSG00000170145(gene)|ensembl:ENST00000304987(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017090(Serine/threonine-protein kinase, SNF1-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR034672	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:h9FQ/a2qA7FtWC0yWI1pK4LTZtA9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P27708	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-355504|uniprotkb:Q6P0Q0|uniprotkb:D6W552|ensembl:ENSP00000264705|uniprotkb:Q96CK3	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:pyr1_human(display_long)|uniprotkb:CAD(gene name)|psi-mi:CAD(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_004332.2|ensembl:ENSG00000084774(gene)|ensembl:ENST00000264705(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014075"(response to amine)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017144"|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051414"(response to cortisol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070335"(aspartate binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR032466|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036901|interpro:IPR036914|mint:P27708|go:"GO:0016020"(membrane)|rcsb pdb:4BY3|rcsb pdb:4C6B|rcsb pdb:4C6C|rcsb pdb:4C6D|rcsb pdb:4C6E|rcsb pdb:4C6F|rcsb pdb:4C6I|rcsb pdb:4C6J|rcsb pdb:4C6K|rcsb pdb:4C6L|rcsb pdb:4C6M|rcsb pdb:4C6N|rcsb pdb:4C6O|rcsb pdb:4C6P|rcsb pdb:4C6Q|rcsb pdb:5G1N|rcsb pdb:5G1O|rcsb pdb:5G1P|rcsb pdb:5YNZ|rcsb pdb:6HFD|rcsb pdb:6HFE|rcsb pdb:6HFF|rcsb pdb:6HFH|rcsb pdb:6HFI|rcsb pdb:6HFJ|rcsb pdb:6HFK|rcsb pdb:6HFL|rcsb pdb:6HFP|rcsb pdb:6HFQ|rcsb pdb:6HFR|rcsb pdb:6HFS|rcsb pdb:6HFU|rcsb pdb:6HG1|reactome:R-HSA-500753|rcsb pdb:6HFN|refseq:NP_001293008.1|dip:DIP-39484N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:m5iR4BQz6t2dbQxtP1MARVW0LAw9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P62266	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-353072|ensembl:ENSP00000296674|ensembl:ENSP00000498621|uniprotkb:P39028|uniprotkb:Q6IB08	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rs23_human(display_long)|uniprotkb:RPS23(gene name)|psi-mi:RPS23(display_short)|uniprotkb:Small ribosomal subunit protein uS12(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000186468(gene)|ensembl:ENST00000296674(transcript)|ensembl:ENST00000651545(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0034063"(stress granule assembly)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:1990145"(maintenance of translational fidelity)|interpro:IPR005680(Ribosomal protein S23, eukaryotic/archaeal)|interpro:IPR006032(Ribosomal protein S12/S23)|rcsb pdb:5T2C|rcsb pdb:5VYC|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|mint:P62266|rcsb pdb:6G4W|rcsb pdb:4CXG|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:4CXH|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:4UG0|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|refseq:NP_001016.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:MWZPvSL/G45ocaxA5AXKCkDQxNU9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q05639	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-354943|ensembl:ENSP00000217182|uniprotkb:P54266|uniprotkb:Q0VGC7|uniprotkb:B5BUF3|uniprotkb:E1P5J1	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:ef1a2_human(display_long)|uniprotkb:EEF1A2(gene name)|psi-mi:EEF1A2(display_short)|uniprotkb:EEF1AL(gene name synonym)|uniprotkb:STN(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-2(gene name synonym)|uniprotkb:Statin-S1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000101210(gene)|ensembl:ENST00000217182(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0090218"(positive regulation of lipid kinase activity)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:Q05639|rcsb pdb:3C5J|reactome:R-HSA-156842|refseq:NP_001949.1|dip:DIP-40060N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:vFXfcSRokxKo5RW0tRE1qEK0NKw9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P83731	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-353146|ensembl:ENSP00000377640|uniprotkb:P38663|uniprotkb:Q6IBS3|uniprotkb:B2R4Y3	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rl24_human(display_long)|uniprotkb:RPL24(gene name)|psi-mi:RPL24(display_short)|uniprotkb:60S ribosomal protein L30(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL24(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	go:"GO:0016020"(membrane)|go:"GO:0021554"(optic nerve development)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR000988(Ribosomal protein L24e)|interpro:IPR011017(TRASH)|interpro:IPR023442|interpro:IPR038630|mint:P83731|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZMI|rcsb pdb:6ZME|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000114391(gene)|ensembl:ENST00000394077(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0010458"(exit from mitosis)|refseq:NP_000977.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:+Ah+YGgcjqOsk5ZS1HZUMQA/Of89606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P18621	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-726937|uniprotkb:Q6NZ54|uniprotkb:Q7M4M5|uniprotkb:Q3KQW2|uniprotkb:B2R4H3|uniprotkb:B4E3C2|uniprotkb:B5ME31|uniprotkb:J3QL51|ensembl:ENSP00000462023|ensembl:ENSP00000462385|ensembl:ENSP00000463842|ensembl:ENSP00000480555|ensembl:ENSP00000482577	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rl17_human(display_long)|uniprotkb:60S ribosomal protein L23(gene name synonym)|uniprotkb:PD-1(gene name synonym)|uniprotkb:RPL17(gene name)|psi-mi:RPL17(display_short)|uniprotkb:Large ribosomal subunit protein uL22(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_000976.1|refseq:NP_001030178.1|refseq:NP_001186269.1|refseq:NP_001186270.1|refseq:NP_001186271.1|refseq:NP_001186272.1|refseq:NP_001186273.1|refseq:NP_001186274.1|ensembl:ENSG00000265681(gene)|ensembl:ENST00000579248(transcript)|ensembl:ENST00000579408(transcript)|ensembl:ENST00000580261(transcript)|ensembl:ENST00000618613(transcript)|ensembl:ENST00000618619(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001063(Ribosomal protein L22/L17)|interpro:IPR005721(Ribosomal protein L22/L17, eukaryotic/archaeal)|interpro:IPR018260|interpro:IPR036394|mint:P18621|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:/i0W3WoeFakz+8R/YMYf2JQZytI9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q92841-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-746027	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q92841-1(display_long)|uniprotkb:DEAD box protein p82(gene name synonym)|uniprotkb:DDX17(gene name)|psi-mi:DDX17(display_short)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:DEAD box protein p72(gene name synonym)|uniprotkb:RNA-dependent helicase p72(gene name synonym)|uniprotkb:p72(isoform synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-746012(ddx17_human)	psi-mi:"MI:0469"(intact)	-	isoform-comment:Produced by alternative initiation at Met-80 of isoform 1.	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:gbbMmoghsssWsMXlfgiV8Pg2Bf49606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:O94761	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-722861|uniprotkb:Q3Y424|uniprotkb:Q96DW2|uniprotkb:A0A087WZ30|uniprotkb:Q96F55|ensembl:ENSP00000482313	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:recq4_human(display_long)|uniprotkb:RecQ protein-like 4(gene name synonym)|uniprotkb:RTS(gene name synonym)|uniprotkb:RECQL4(gene name)|psi-mi:RECQL4(display_short)|uniprotkb:RECQ4(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_004251.3|ensembl:ENSG00000160957(gene)|ensembl:ENST00000617875(transcript)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0016020"(membrane)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021110|interpro:IPR027417|rcsb pdb:2KMU|rcsb pdb:5LST|dip:DIP-48475N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:FMX8OqwUNPdPfNL6EsLucTQCNfQ9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q8IX01-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-949129|ensembl:ENSP00000337926|ensembl:ENSP00000389380|ensembl:ENSP00000472286	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q8ix01-1(display_long)|uniprotkb:SUGP2(gene name)|psi-mi:SUGP2(display_short)|uniprotkb:KIAA0365(gene name synonym)|uniprotkb:Arginine/serine-rich-splicing factor 14(gene name synonym)|uniprotkb:SFRS14(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 14(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000064607(gene)|ensembl:ENST00000337018(transcript)|ensembl:ENST00000452918(transcript)|ensembl:ENST00000601879(transcript)|intact:EBI-949116(sfr14_human)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:hN1zWaoMMufKCQNO9VQ8NPiN0hI9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P08779	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356410|uniprotkb:P30654|uniprotkb:Q16402|uniprotkb:Q9UBG8|uniprotkb:A8K488|ensembl:ENSP00000301653	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:k1c16_human(display_long)|uniprotkb:KRT16(gene name)|psi-mi:KRT16(display_short)|uniprotkb:KRT16A(gene name synonym)|uniprotkb:Keratin-16(gene name synonym)|uniprotkb:Cytokeratin-16(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_005548.2|ensembl:ENSG00000186832(gene)|ensembl:ENST00000301653(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0006954"(inflammatory response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007568"(aging)|go:"GO:0030216"(keratinocyte differentiation)|reactome:R-HSA-6805567|reactome:R-HSA-6809371|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031424"(keratinization)|go:"GO:0042633"(hair cycle)|go:"GO:0045087"(innate immune response)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0051546"(keratinocyte migration)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P08779	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:NkPTLkWquNNlGYbrXaRkyRmKvmM9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P62280	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1047710|uniprotkb:B2R4F5|uniprotkb:P04643|uniprotkb:Q498Y6|uniprotkb:Q6IRY0|ensembl:ENSP00000270625	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rs11_human(display_long)|uniprotkb:RPS11(gene name)|psi-mi:RPS11(display_short)|uniprotkb:Small ribosomal subunit protein uS17(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001006.1|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000266(Ribosomal protein S17)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019979|interpro:IPR028333|interpro:IPR032440|mint:P62280|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|go:"GO:0005840"(ribosome)|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|ensembl:ENSG00000142534(gene)|ensembl:ENST00000270625(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6OM0|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:0fqJjtWAuz31VTKt2mbteRoi8vA9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q9Y580	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-746903|uniprotkb:Q9NUT4|uniprotkb:B2R6K8|ensembl:ENSP00000439918	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rbm7_human(display_long)|uniprotkb:RNA-binding motif protein 7(gene name synonym)|uniprotkb:RBM7(gene name)|psi-mi:RBM7(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001272974.1|refseq:NP_001272975.1|refseq:NP_001272976.1|refseq:NP_001272977.1|refseq:NP_057174.1|ensembl:ENSG00000076053(gene)|ensembl:ENST00000540163(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0017069"(snRNA binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034500|interpro:IPR035979|mint:Q9Y580|rcsb pdb:2M8H|rcsb pdb:5IQQ|rcsb pdb:5LXR|rcsb pdb:5LXY|dip:DIP-48833N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:d39RjBQTHAVQlOsmrxMX0NCR8CU9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P13647	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-702187|uniprotkb:Q6PI71|uniprotkb:Q6UBJ0|uniprotkb:Q8TA91|ensembl:ENSP00000252242	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:k2c5_human(display_long)|uniprotkb:Cytokeratin-5(gene name synonym)|uniprotkb:58 kDa cytokeratin(gene name synonym)|uniprotkb:KRT5(gene name)|psi-mi:KRT5(display_short)|uniprotkb:Keratin-5(gene name synonym)|uniprotkb:Type-II keratin Kb5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_000415.2|dip:DIP-39N|ensembl:ENSG00000186081(gene)|ensembl:ENST00000252242(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0045095"(keratin filament)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P13647|rcsb pdb:3TNU|rcsb pdb:6JFV|reactome:R-HSA-446107|reactome:R-HSA-6805567|reactome:R-HSA-6809371	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:BdtVgSlWFYS/+zyXLNxvrcSWc4I9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P08107	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:"GO:0005829"(cytosol)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0030529"|go:"GO:0005524"(ATP binding)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0042026"(protein refolding)|go:"GO:0006986"(response to unfolded protein)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0031982"(vesicle)|go:"GO:0010467"(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0050821"(protein stabilization)|go:"GO:0005654"(nucleoplasm)|go:"GO:1900034"(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:"GO:0016235"(aggresome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0001618"(virus receptor activity)|rcsb pdb:4J8F|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016234"(inclusion body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044822"|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0005814"(centriole)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042623"|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR029047|interpro:IPR029048|ensembl:ENST00000375650|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0031397"(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:NFv4uj12xAWIr+OltarRlLDPr949606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P35908	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1247312|uniprotkb:Q4VAQ2|ensembl:ENSP00000310861	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:k22e_human(display_long)|uniprotkb:KRT2(gene name)|psi-mi:KRT2(display_short)|uniprotkb:KRT2A(gene name synonym)|uniprotkb:KRT2E(gene name synonym)|uniprotkb:Cytokeratin-2e(gene name synonym)|uniprotkb:Keratin-2e(gene name synonym)|uniprotkb:Type-II keratin Kb2(gene name synonym)|uniprotkb:Keratin-2 epidermis(gene name synonym)|uniprotkb:Epithelial keratin-2e(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_000414.2|ensembl:ENSG00000172867(gene)|ensembl:ENST00000309680(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0003334"(keratinocyte development)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0031424"(keratinization)|go:"GO:0032980"(keratinocyte activation)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0045095"(keratin filament)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045684"(positive regulation of epidermis development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P35908|reactome:R-HSA-6805567|reactome:R-HSA-6809371|go:"GO:0051546"(keratinocyte migration)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:T7LeB8nkZzNjUb8DWdkxbrl5f789606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	intact:EBI-2211147	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	-	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:a8mq54_human(display_short)|psi-mi:EBI-2211147(display_long)|uniprotkb:SOGA2(gene name)|psi-mi:SOGA2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	uniprotkb:A8MQ54(uniprot-removed-ac)	psi-mi:"MI:0469"(intact)	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:JYVXj18UYIwgtlgld5mt2gWkMYE9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P13645	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-465144|ensembl:ENSP00000269576|uniprotkb:Q14664|uniprotkb:Q8N175	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:k1c10_human(display_long)|uniprotkb:KRT10(gene name)|psi-mi:KRT10(display_short)|uniprotkb:Cytokeratin-10(gene name synonym)|uniprotkb:KPP(gene name synonym)|uniprotkb:Keratin-10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000186395(gene)|ensembl:ENST00000269576(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0045684"(positive regulation of epidermis development)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P13645|rcsb pdb:3ASW|rcsb pdb:4F1Z|rcsb pdb:4ZRY|rcsb pdb:6E2J|rcsb pdb:6EC0|rcsb pdb:6UUI|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_000412.3	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:z100yyq3b63P0ARy2lE2ELyJeik9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q9NUC0	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1773811|uniprotkb:B2RD32|ensembl:ENSP00000355979|ensembl:ENSP00000486369	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:srtd4_human(display_long)|uniprotkb:SERTAD4(gene name)|psi-mi:SERTAD4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_062551.1|ensembl:ENSG00000082497(gene)|ensembl:ENSG00000281230(gene)|ensembl:ENST00000367012(transcript)|ensembl:ENST00000630425(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR009263(SERTA)|interpro:IPR029708	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:us8AIu8sIAtj+ZOqwAH2vzWE0ik9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q9BXL8	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1773949|uniprotkb:Q8TB18|uniprotkb:Q9NWK7|ensembl:ENSP00000337226|ensembl:ENSP00000376369	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:cdca4_human(display_long)|uniprotkb:CDCA4(gene name)|psi-mi:CDCA4(display_short)|uniprotkb:HEPP(gene name synonym)|uniprotkb:Hematopoietic progenitor protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_060425.2|refseq:NP_663747.1|ensembl:ENSG00000170779(gene)|ensembl:ENST00000336219(transcript)|ensembl:ENST00000392590(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0048096"|interpro:IPR009263(SERTA)|mint:Q9BXL8	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:sxwZ0Yw0uG+MjnhKtVv+8PHvPCo9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P47756-2	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-353608|ensembl:ENSP00000264202	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:p47756-2(display_long)|uniprotkb:CAPZB(gene name)|psi-mi:CAPZB(display_short)|uniprotkb:CapZ beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-353595(capzb_human)|ensembl:ENSG00000077549(gene)|ensembl:ENST00000264202(transcript)|uniprotkb:P47756-2(isoform-parent)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:48IQ1CJkjL9DdUW66uFlFKhRWxo9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P48643	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P17987	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P62714	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P40227	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P50991	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q99832	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q9Y4B5	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-302423|uniprotkb:Q6ZMQ9|uniprotkb:Q8IWA9|intact:EBI-28975975|ensembl:ENSP00000305027|intact:EBI-2554582|uniprotkb:E9PAY7	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:mtcl1_human(display_long)|uniprotkb:MTCL1(gene name)|psi-mi:MTCL1(display_short)|uniprotkb:CCDC165(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 165(gene name synonym)|uniprotkb:KIAA0802(gene name synonym)|uniprotkb:PAR-1-interacting protein(gene name synonym)|uniprotkb:SOGA family member 2(gene name synonym)|uniprotkb:SOGA2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_056025.2|ensembl:ENSG00000168502(gene)|ensembl:ENST00000306329(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008017"(microtubule binding)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030496"(midbody)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097427"(microtubule bundle)|go:"GO:2000576"(obsolete positive regulation of microtubule motor activity)|interpro:IPR027881|interpro:IPR027882|ensembl:ENSP00000305027|ensembl:ENST00000359865|ensembl:ENSP00000352927|ensembl:ENST00000400050|ensembl:ENSP00000382924|ensembl:ENSP00000429556|ensembl:ENST00000518815|ensembl:ENSP00000463465|ensembl:ENST00000517570|refseq:XP_005258156.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:RxNB5mpEiLNQpsyKLfaw0LyqsVU9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:O95816	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q96BD8	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-741854|uniprotkb:B2R9Y6|uniprotkb:B4E0P4|ensembl:ENSP00000285116|ensembl:ENSP00000381470|ensembl:ENSP00000458992|ensembl:ENSP00000478259	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:ska1_human(display_long)|uniprotkb:SKA1(gene name)|psi-mi:SKA1(display_short)|uniprotkb:C18orf24(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001034624.1|refseq:NP_659497.1|ensembl:ENSG00000154839(gene)|ensembl:ENSG00000262634(gene)|ensembl:ENST00000285116(transcript)|ensembl:ENST00000398452(transcript)|ensembl:ENST00000571751(transcript)|ensembl:ENST00000616604(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|interpro:IPR009829(Protein of unknown function DUF1395)|interpro:IPR042031|mint:Q96BD8|rcsb pdb:4AJ5|rcsb pdb:4C9Y|rcsb pdb:4CA0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:Z7y57MeLsUJK0R9JNqHJNBbKr/89606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q8IX90-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1773985|ensembl:ENSP00000319417	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q8ix90-1(display_long)|uniprotkb:SKA3(gene name)|psi-mi:SKA3(display_short)|uniprotkb:C13orf3(gene name synonym)|uniprotkb:RAMA1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-1773976(isoform-parent)|ensembl:ENSG00000165480(gene)|ensembl:ENST00000314759(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:F3lm7ntNHVutZ+X66pTMEfyyJ+E9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P78371	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P30153	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P49368	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P30154	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P67775	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q8WVK7	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1773994|uniprotkb:A6NIL3|uniprotkb:B3KPL3|uniprotkb:E9PCB8|ensembl:ENSP00000333433	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:ska2_human(display_long)|uniprotkb:SKA2(gene name)|psi-mi:SKA2(display_short)|uniprotkb:FAM33A(gene name synonym)|uniprotkb:Protein FAM33A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001094065.1|refseq:NP_872426.1|ensembl:ENSG00000182628(gene)|ensembl:ENST00000330137(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0051301"(cell division)|interpro:IPR026762|interpro:IPR042091|mint:Q8WVK7|rcsb pdb:4AJ5|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:OxuqjB9I67fkmxHRa5g1u6KMvAg9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P50990	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2210942|imex:IM-9155-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606	intact-crc:EE62B86EB8374E87|rigid:JsQ3DiUzQT3WVEgmbOPyn5CjmD8	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q562F6-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-989225|ensembl:ENSP00000350447	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q562f6-1(display_long)|uniprotkb:SGO2(gene name)|psi-mi:SGO2(display_short)|uniprotkb:SGOL2(gene name synonym)|uniprotkb:Shugoshin-2(gene name synonym)|uniprotkb:Shugoshin-like 2(gene name synonym)|uniprotkb:Tripin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000163535(gene)|ensembl:ENST00000357799(transcript)|intact:EBI-989213(sgol2_human)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:lj8jTnNLhIEEqgqjvOrIJIS57yc9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q8NC51-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-523570|ensembl:ENSP00000360034	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q8nc51-1(display_long)|uniprotkb:SERBP1(gene name)|psi-mi:SERBP1(display_short)|uniprotkb:PAIRBP1(gene name synonym)|uniprotkb:PAI1 RNA-binding protein 1(gene name synonym)|uniprotkb:SERPINE1 mRNA-binding protein 1(gene name synonym)|uniprotkb:CGI-55(orf name)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-523558(pairb_human)|ensembl:ENSG00000142864(gene)|ensembl:ENST00000370995(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:lVkIPRkoXs3B4Qop1pA2zG/RKlo9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P62888	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-353116|uniprotkb:P04645|uniprotkb:Q502Z6|ensembl:ENSP00000287038|ensembl:ENSP00000428085|uniprotkb:B2R591	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rl30_human(display_long)|uniprotkb:RPL30(gene name)|psi-mi:RPL30(display_short)|uniprotkb:Large ribosomal subunit protein eL30(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000156482(gene)|ensembl:ENST00000287038(transcript)|ensembl:ENST00000521291(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000231(Ribosomal protein L30e)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR022991|interpro:IPR029064|interpro:IPR039109|mint:P62888|rcsb pdb:3VI6|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000980.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:xR9LwYg6N7m9njT1pYumOPKZVu49606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P24534	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-354334|uniprotkb:Q6IBH9|uniprotkb:A8K795|ensembl:ENSP00000236957|ensembl:ENSP00000376055|ensembl:ENSP00000376056|ensembl:ENSP00000489993|ensembl:ENSP00000490214|ensembl:ENSP00000490326	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:ef1b_human(display_long)|uniprotkb:EEF1B(gene name synonym)|uniprotkb:EF1B(gene name synonym)|uniprotkb:EEF1B2(gene name)|psi-mi:EEF1B2(display_short)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001032752.1|refseq:NP_001950.1|refseq:NP_066944.1|ensembl:ENSG00000114942(gene)|ensembl:ENSG00000283391(gene)|ensembl:ENST00000236957(transcript)|ensembl:ENST00000392221(transcript)|ensembl:ENST00000392222(transcript)|ensembl:ENST00000635728(transcript)|ensembl:ENST00000636275(transcript)|ensembl:ENST00000637253(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006414"(translational elongation)|go:"GO:0045471"(response to ethanol)|interpro:IPR001326(Translation elongation factor EF1B, beta/delta chains, conserved site)|interpro:IPR014038(Translation elongation factor EF1B, beta and delta chains, guanine nucleotide exchange)|interpro:IPR014717(Translation elongation  factor EF1B/ribosomal protein S6)|interpro:IPR018940|interpro:IPR036219|interpro:IPR036282|mint:P24534|rcsb pdb:1B64|rcsb pdb:5DQS|reactome:R-HSA-156842	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:d4zkwQOMlpr6XBapMfT1sxy2ZPs9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q8N1N4	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1056564|uniprotkb:Q7RTT2|uniprotkb:Q5HYM7|uniprotkb:A8K4D6|ensembl:ENSP00000306261	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:k2c78_human(display_long)|uniprotkb:KRT78(gene name)|psi-mi:KRT78(display_short)|uniprotkb:K5B(gene name synonym)|uniprotkb:KB40(gene name synonym)|uniprotkb:Cytokeratin-78(gene name synonym)|uniprotkb:Type-II keratin Kb40(gene name synonym)|uniprotkb:Keratin-5b(gene name synonym)|uniprotkb:Keratin-78(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001287743.1|refseq:NP_775487.2|ensembl:ENSG00000170423(gene)|ensembl:ENST00000304620(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:7DFQlPKPQ4Bu1Q5+nxLQufA7ghU9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q96EP5-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-2133395|ensembl:ENSP00000233078	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q96ep5-1(display_long)|uniprotkb:DAZAP1(gene name)|psi-mi:DAZAP1(display_short)|uniprotkb:Deleted in azoospermia-associated protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-2133162(isoform-parent)|ensembl:ENSG00000071626(gene)|ensembl:ENST00000233078(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:4uZCZTXZGnZAD9tBcurmc8RhGwY9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P67809	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P14866	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-719024|uniprotkb:Q9H3P3|uniprotkb:A6ND69|uniprotkb:A6NIT8|ensembl:ENSP00000221419|ensembl:ENSP00000489021	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:hnrpl_human(display_long)|uniprotkb:HNRPL(gene name synonym)|uniprotkb:HNRNPL(gene name)|psi-mi:HNRNPL(display_short)|uniprotkb:P/OKcl.14(orf name)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001005335.1|refseq:NP_001524.2|refseq:XP_011525191.1|ensembl:ENSG00000282947(gene)|ensembl:ENST00000221419(transcript)|ensembl:ENST00000634753(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097157"(pre-mRNA intronic binding)|ensembl:ENSG00000104824(gene)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034816|interpro:IPR034817|interpro:IPR035005|interpro:IPR035008|interpro:IPR035979|mint:P14866|rcsb pdb:3R27|rcsb pdb:3TO8|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:1990904"(ribonucleoprotein complex)|dip:DIP-36355N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:vOfznm03e6Ottg6BptYHmR9qJEc9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P84098	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-916524|uniprotkb:P14118|uniprotkb:P22908|uniprotkb:Q502Y6|uniprotkb:Q7Z6E4|uniprotkb:B2R4K2|ensembl:ENSP00000225430	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rl19_human(display_long)|uniprotkb:RPL19(gene name)|psi-mi:RPL19(display_short)|uniprotkb:Large ribosomal subunit protein eL19(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_000972.1|ensembl:ENSG00000108298(gene)|ensembl:ENST00000225430(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0097421"(liver regeneration)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR000196(Ribosomal protein L19/L19e)|interpro:IPR015972(Ribosomal protein L19/L19e, domain 1)|interpro:IPR023638|interpro:IPR033935|interpro:IPR035970|interpro:IPR039547|mint:P84098|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:sYEwdB8ySbxh3iL0uqlfRRVFiWw9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P30050-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1856516|ensembl:ENSP00000354739	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:p30050-1(display_long)|uniprotkb:RPL12(gene name)|psi-mi:RPL12(display_short)|uniprotkb:Large ribosomal subunit protein uL11(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-352743(isoform-parent)|ensembl:ENSG00000197958(gene)|ensembl:ENST00000361436(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:TNPEtl60cILofaPzUznvZiw6D7E9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P07477	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1222902|uniprotkb:A6NJ71|uniprotkb:Q92955|uniprotkb:Q9HAN4|uniprotkb:Q9HAN5|uniprotkb:Q9HAN6|uniprotkb:Q9HAN7|intact:EBI-1760472|intact:EBI-1965533|uniprotkb:A1A509|uniprotkb:Q5NV57|uniprotkb:Q7M4N3|uniprotkb:Q7M4N4|uniprotkb:B2R5I5|ensembl:ENSP00000308720|ensembl:ENSP00000479217	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:try1_human(display_long)|uniprotkb:PRSS1(gene name)|psi-mi:PRSS1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:TRY1(gene name synonym)|uniprotkb:TRYP1(gene name synonym)|uniprotkb:Trypsin I(gene name synonym)|uniprotkb:Cationic trypsinogen(gene name synonym)|uniprotkb:Serine protease 1(gene name synonym)|uniprotkb:Beta-trypsin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_002760.1|ensembl:ENSG00000204983(gene)|ensembl:ENSG00000274247(gene)|ensembl:ENST00000311737(transcript)|ensembl:ENST00000616256(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072562"(blood microparticle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P07477|rcsb pdb:1FXY|rcsb pdb:1TRN|rcsb pdb:2RA3|rcsb pdb:4WWY|rcsb pdb:4WXV|reactome:R-HSA-1592389|reactome:R-HSA-196741	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:2elS/qMYj0sflxilyWfk3KPtGmo9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q13011	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-711968|ensembl:ENSP00000221418|ensembl:ENSP00000489530|uniprotkb:Q8WVX0|uniprotkb:Q96EZ9|uniprotkb:A8K745	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:ech1_human(display_long)|uniprotkb:ECH1(gene name)|psi-mi:ECH1(display_short)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000104823(gene)|ensembl:ENSG00000282853(gene)|ensembl:ENST00000221418(transcript)|ensembl:ENST00000634245(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016020"(membrane)|go:"GO:0051750"("delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity")|go:"GO:0070062"(extracellular exosome)|interpro:IPR001753(Crotonase, core)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR018376|interpro:IPR029045|mint:Q13011|rcsb pdb:2VRE|reactome:R-HSA-9033241|refseq:NP_001389.2	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:gh0bwdUu9tkSTHWuySCaTXIQGzI9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P05386	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-354582|uniprotkb:A6NIB2|ensembl:ENSP00000346037	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rla1_human(display_long)|uniprotkb:RPLP1(gene name)|psi-mi:RPLP1(display_short)|uniprotkb:RRP1(gene name synonym)|uniprotkb:Large ribosomal subunit protein P1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_000994.1|refseq:NP_998890.1|ensembl:ENSG00000137818(gene)|ensembl:ENST00000260379(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR027534|interpro:IPR038716|mint:P05386|rcsb pdb:2LBF|rcsb pdb:4BEH|rcsb pdb:4V6X|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:rHSXz4ZCJy+JH6OrjUgHiTK85mo9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P11940-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-352013|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:p11940-1(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-81531(pabp1_human)|ensembl:ENSG00000070756(gene)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:XudTSPq2h9ckKAc48X88RVafPRU9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:O15294-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-539844|ensembl:ENSP00000362824	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:o15294-1(display_long)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:Nucleocytoplasmic isoform(isoform synonym)|uniprotkb:ncOGT(isoform synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-539828(ogt1_human)|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q14974	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P62258	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P62826	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P50914	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356746|uniprotkb:Q45RF0|uniprotkb:Q53G20|uniprotkb:Q8TBD5|uniprotkb:Q8WUT0|uniprotkb:Q92579|uniprotkb:Q96GR0|uniprotkb:Q9BSB8|uniprotkb:Q9BW65|uniprotkb:Q9BYF6|ensembl:ENSP00000345156|ensembl:ENSP00000379506	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rl14_human(display_long)|uniprotkb:RPL14(gene name)|psi-mi:RPL14(display_short)|uniprotkb:CAG-ISL 7(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL14(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001030168.1|refseq:NP_003964.3|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002784(Ribosomal protein L14)|interpro:IPR008991(Translation protein SH3-like)|ensembl:ENSG00000188846(gene)|ensembl:ENST00000338970(transcript)|ensembl:ENST00000396203(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041985|mint:P50914|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|interpro:IPR039660|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y2L	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:AjaguD5hgHtcBbJq5QfuG6XdTcE9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q71UM5	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-355126|uniprotkb:Q9BTJ1|ensembl:ENSP00000331019	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rs27l_human(display_long)|uniprotkb:RPS27L(gene name)|psi-mi:RPS27L(display_short)|uniprotkb:Small ribosomal subunit protein eS27-like(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_057004.1|ensembl:ENSG00000185088(gene)|ensembl:ENST00000330964(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0006412"(translation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008494"(translation activator activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:Q71UM5|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:OVIAlDF6dN3DxLZgQFrFl8r0Z0I9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P22626-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-432518|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:p22626-1(display_long)|uniprotkb:hnRNP B1(isoform synonym)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|ensembl:ENST00000679001(transcript)|ensembl:ENST00000679021(transcript)|ensembl:ENST00000679123(transcript)|intact:EBI-299649(roa2_human)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q02878	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-359655|uniprotkb:Q2M3Q3|uniprotkb:Q8WW97|ensembl:ENSP00000202773|ensembl:ENSP00000403172	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rl6_human(display_long)|uniprotkb:RPL6(gene name)|psi-mi:RPL6(display_short)|uniprotkb:TXREB1(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Neoplasm-related protein C140(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_000961.2|refseq:NP_001019833.1|ensembl:ENSG00000089009(gene)|ensembl:ENST00000202773(transcript)|ensembl:ENST00000424576(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:Q02878|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001307066.1|refseq:NP_001307067.1|refseq:NP_001307068.1|refseq:NP_001307069.1|refseq:NP_001307070.1|refseq:XP_016875270.1|refseq:XP_016875271.1|dip:DIP-27547N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:Y7fx3ToInzucV2QmI8KLSdHxai09606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q13162	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-2211957|uniprotkb:Q6FHT3|ensembl:ENSP00000368646	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:prdx4_human(display_long)|uniprotkb:PRDX4(gene name)|psi-mi:PRDX4(display_short)|uniprotkb:Peroxiredoxin IV(gene name synonym)|uniprotkb:Thioredoxin peroxidase AO372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase A0372(gene name synonym)|uniprotkb:Antioxidant enzyme AOE372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_006397.1|ensembl:ENSG00000123131(gene)|ensembl:ENST00000379341(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000255"(negative regulation of male germ cell proliferation)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:Q13162|rcsb pdb:2PN8|rcsb pdb:3TJB|rcsb pdb:3TJF|rcsb pdb:3TJG|rcsb pdb:3TJJ|rcsb pdb:3TJK|rcsb pdb:3TKP|rcsb pdb:3TKQ|rcsb pdb:3TKR|rcsb pdb:3TKS|rcsb pdb:4RQX|rcsb pdb:5HQP|reactome:R-HSA-6798695	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:5KWl3YuUpRDrSUxWlJS6sP7CLAs9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q9NTJ3-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356195|ensembl:ENSP00000341382|ensembl:ENSP00000349961	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q9ntj3-1(display_long)|uniprotkb:SMC4(gene name)|psi-mi:SMC4(display_short)|uniprotkb:CAPC(gene name synonym)|uniprotkb:SMC4L1(gene name synonym)|uniprotkb:Chromosome-associated polypeptide C(gene name synonym)|uniprotkb:XCAP-C homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-356173(smc4_human)|ensembl:ENSG00000113810(gene)|ensembl:ENST00000344722(transcript)|ensembl:ENST00000357388(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:+2lnTSgTXZwRawJ/ASBRa6EDgv09606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q8NDX1-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-2211922|ensembl:ENSP00000245796	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q8ndx1-1(display_long)|uniprotkb:TIC(gene name synonym)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 4(gene name synonym)|uniprotkb:Telomeric of interleukin-1 cluster protein(gene name synonym)|uniprotkb:PSD4(gene name)|psi-mi:PSD4(display_short)|uniprotkb:EFA6B(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-2211897(isoform-parent)|ensembl:ENSG00000125637(gene)|ensembl:ENST00000245796(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:hplz7/MuMAkCWkpHwXKuiHO9U/k9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P62424	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-354172|uniprotkb:P11518|uniprotkb:Q5T8U4|ensembl:ENSP00000361076|ensembl:ENSP00000487443	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rl7a_human(display_long)|uniprotkb:RPL7A(gene name)|psi-mi:RPL7A(display_short)|uniprotkb:SURF-3(gene name synonym)|uniprotkb:SURF3(gene name synonym)|uniprotkb:Surfeit locus protein 3(gene name synonym)|uniprotkb:PLA-X polypeptide(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_000963.1|dip:DIP-31502N|ensembl:ENSG00000148303(gene)|ensembl:ENSG00000280858(gene)|ensembl:ENST00000323345(transcript)|ensembl:ENST00000630979(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR001921(Ribosomal protein L7A)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:P62424|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|go:"GO:0005634"(nucleus)|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:shPtLmc+oabT/rSwho+tP1iJy4k9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q14532	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1044146|ensembl:ENSP00000225899	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:k1h2_human(display_long)|uniprotkb:KRT32(gene name)|psi-mi:KRT32(display_short)|uniprotkb:HHA2(gene name synonym)|uniprotkb:HKA2(gene name synonym)|uniprotkb:Hair keratin, type I Ha2(gene name synonym)|uniprotkb:Keratin-32(gene name synonym)|uniprotkb:KRTHA2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000108759(gene)|ensembl:ENST00000225899(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018039|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_002269.3	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:fbPhQU7W0HKcorCfIL28y6rckrc9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P46778	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-350634|uniprotkb:Q16699|ensembl:ENSP00000346027|ensembl:ENSP00000351021|ensembl:ENSP00000370569|ensembl:ENSP00000370574	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rl21_human(display_long)|uniprotkb:RPL21(gene name)|psi-mi:RPL21(display_short)|uniprotkb:Large ribosomal subunit protein eL21(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	rcsb pdb:6LU8|refseq:NP_000973.2|ensembl:ENSG00000122026(gene)|ensembl:ENST00000272274(transcript)|ensembl:ENST00000311549(transcript)|ensembl:ENST00000319826(transcript)|ensembl:ENST00000326092(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001147(Ribosomal protein L21e)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018259|interpro:IPR036948|mint:P46778|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6OLE|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:UCth+WL9Oj1Y9I5m4i/9X0a5WHk9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P62241	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-351811|uniprotkb:Q6IRL7|uniprotkb:P09058|ensembl:ENSP00000379888	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rs8_human(display_long)|uniprotkb:RPS8(gene name)|psi-mi:RPS8(display_short)|uniprotkb:Small ribosomal subunit protein eS8(gene name synonym)|uniprotkb:OK/SW-cl.83(orf name)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001003.1|ensembl:ENSG00000142937(gene)|ensembl:ENST00000396651(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001047(Ribosomal protein S8e)|interpro:IPR018283|interpro:IPR022309|interpro:IPR042563|mint:P62241|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:6G5H|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975957|reactome:R-HSA-975956	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:3rpCBdQyRWR+TCKnupbnCp30jKE9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P30048	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-748336|intact:EBI-10975142|uniprotkb:P35690|uniprotkb:Q0D2H1|uniprotkb:Q13776|uniprotkb:Q5T5V2|uniprotkb:Q96HK4|uniprotkb:B2R7Z0|uniprotkb:D3DRC9|uniprotkb:E9PH29|ensembl:ENSP00000298510	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:prdx3_human(display_long)|uniprotkb:Peroxiredoxin-3(gene name synonym)|uniprotkb:Peroxiredoxin III(gene name synonym)|uniprotkb:Antioxidant protein 1(gene name synonym)|uniprotkb:Protein MER5 homolog(gene name synonym)|uniprotkb:HBC189(gene name synonym)|uniprotkb:PRDX3(gene name)|psi-mi:PRDX3(display_short)|uniprotkb:AOP1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001289201.1|refseq:NP_006784.1|ensembl:ENSG00000165672(gene)|ensembl:ENST00000298510(transcript)|go:"GO:0001893"(maternal placenta development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008785"(alkyl hydroperoxide reductase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:P30048|rcsb pdb:5JCG|rcsb pdb:5UCX|reactome:R-HSA-3299685|go:"GO:0005769"(early endosome)|dip:DIP-33600N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:+J/zV8u0jGCSzTGXafxgecTv/149606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q92552	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-2211879|uniprotkb:Q6P1S1|uniprotkb:B4DRT2|ensembl:ENSP00000261413	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rt27_human(display_long)|uniprotkb:MRPS27(gene name)|psi-mi:MRPS27(display_short)|uniprotkb:KIAA0264(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS27(gene name synonym)|uniprotkb:Mitochondrial ribosomal protein S27(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001273677.1|refseq:NP_055899.2|dip:DIP-44136N|ensembl:ENSG00000113048(gene)|ensembl:ENST00000261413(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0008283"(cell population proliferation)|go:"GO:0019843"(rRNA binding)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0097177"(mitochondrial ribosome binding)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019266|interpro:IPR034913|mint:Q92552|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:reHIDm6Of3ERJMBRxVlVntHyRlY9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P43243	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-352602|ensembl:ENSP00000378284|ensembl:ENSP00000482895|uniprotkb:Q9UHW0|uniprotkb:Q9UQ27|uniprotkb:D3DQC3|uniprotkb:B7ZAV5	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:matr3_human(display_long)|uniprotkb:KIAA0723(gene name synonym)|uniprotkb:MATR3(gene name)|psi-mi:MATR3(display_short)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000015479(gene)|ensembl:ENST00000394805(transcript)|ensembl:ENST00000618441(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:P43243|refseq:NP_001181883.1|refseq:NP_001181884.1|refseq:NP_061322.2|refseq:NP_954659.1|refseq:NP_001181885.1|refseq:NP_001269207.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:3UZlyCZHgdr1SBgUctv9Ev7XBSQ9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q9NR30-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-876418|ensembl:ENSP00000346120	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q9nr30-1(display_long)|uniprotkb:DDX21(gene name)|psi-mi:DDX21(display_short)|uniprotkb:DEAD box protein 21(gene name synonym)|uniprotkb:Gu-alpha(gene name synonym)|uniprotkb:Nucleolar RNA helicase Gu(gene name synonym)|uniprotkb:Nucleolar RNA helicase II(gene name synonym)|uniprotkb:RH II/Gu(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-357942(ddx21_human)|ensembl:ENSG00000165732(gene)|ensembl:ENST00000354185(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:NSmxvs3DBWvKpVDEAHIpqy7/b6w9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q07021	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-347528|uniprotkb:Q2HXR8|uniprotkb:Q9NNY8|intact:EBI-15990352|ensembl:ENSP00000225698	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:c1qbp_human(display_long)|uniprotkb:C1QBP(gene name)|psi-mi:C1QBP(display_short)|uniprotkb:GC1QBP(gene name synonym)|uniprotkb:HABP1(gene name synonym)|uniprotkb:SF2P32(gene name synonym)|uniprotkb:Glycoprotein gC1qBP(gene name synonym)|uniprotkb:Hyaluronan-binding protein 1(gene name synonym)|uniprotkb:Mitochondrial matrix protein p32(gene name synonym)|uniprotkb:p33(gene name synonym)|uniprotkb:ASF/SF2-associated protein p32(gene name synonym)|uniprotkb:gC1q-R protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001203.1|dip:DIP-31164N|ensembl:ENSG00000108561(gene)|ensembl:ENST00000225698(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0008494"(translation activator activity)|go:"GO:0009986"(cell surface)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0030984"(kininogen binding)|go:"GO:0031690"(adrenergic receptor binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0039534"(negative regulation of MDA-5 signaling pathway)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097177"(mitochondrial ribosome binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|mint:Q07021|rcsb pdb:1P32|rcsb pdb:3RPX|rcsb pdb:6SZW|reactome:R-HSA-111471|go:"GO:0005886"(plasma membrane)|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9645722|reactome:R-HSA-140837	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:NfZ31HjbYZxd8UQKRXczhpc306E9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P05388	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-354101|uniprotkb:Q9BVK4|intact:EBI-8012155|intact:MINT-8395053|uniprotkb:Q3B7A4|ensembl:ENSP00000339027|ensembl:ENSP00000376299|ensembl:ENSP00000449328	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rla0_human(display_long)|uniprotkb:RPLP0(gene name)|psi-mi:RPLP0(display_short)|uniprotkb:60S ribosomal protein L10E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_000993.1|refseq:NP_444505.1|ensembl:ENSG00000089157(gene)|ensembl:ENST00000228306(transcript)|ensembl:ENST00000392514(transcript)|ensembl:ENST00000551150(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0098794"(postsynapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR030670|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:P05388|rcsb pdb:4V6W|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8950505|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:xv3QHqnXxvCd3BOIeHVkqEnSNNk9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P52815	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-358272|uniprotkb:Q969U0|uniprotkb:Q9HCA2|uniprotkb:Q9UQJ3|ensembl:ENSP00000333837	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rm12_human(display_long)|uniprotkb:MRPL12(gene name)|psi-mi:MRPL12(display_short)|uniprotkb:RPML12(gene name synonym)|uniprotkb:5c5-2(gene name synonym)|uniprotkb:MRPL7(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein bL12m(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_002940.2|ensembl:ENSG00000262814(gene)|ensembl:ENST00000333676(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006412"(translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR000206(Ribosomal protein L7/L12)|interpro:IPR008932(Ribosomal protein L7/L12, oligomerisation)|interpro:IPR013823(Ribosomal protein L7/L12, C-terminal)|interpro:IPR014719(Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like)|interpro:IPR036235|mint:P52815|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|dip:DIP-50865N|rcsb pdb:6ZSG|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:rs6bdQ5j/8fLRbXZqqS6GgR7AzI9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P49756	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-2211856|uniprotkb:Q9UEQ5|uniprotkb:Q9UIE9|uniprotkb:A0PJL9|uniprotkb:B2RNA8|uniprotkb:B3KT03|uniprotkb:Q2TA72|uniprotkb:Q5XJ17|uniprotkb:Q6P665|uniprotkb:Q9H6A1|intact:EBI-2839256|intact:EBI-2859423|ensembl:ENSP00000261973|ensembl:ENSP00000431150	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rbm25_human(display_long)|uniprotkb:RBM25(gene name)|psi-mi:RBM25(display_short)|uniprotkb:RNPC7(gene name synonym)|uniprotkb:RNA-binding motif protein 25(gene name synonym)|uniprotkb:RNA-binding region-containing protein 7(gene name synonym)|uniprotkb:Protein S164(gene name synonym)|uniprotkb:Arg/Glu/Asp-rich protein of 120 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:XP_011535346.1|refseq:NP_067062.1|refseq:XP_011535347.1|ensembl:ENSG00000119707(gene)|ensembl:ENST00000261973(transcript)|ensembl:ENST00000527432(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR034268|interpro:IPR035979|interpro:IPR036483|mint:P49756|rcsb pdb:3V53|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:VRZ6bJro7qw+BXS0rpYZoiD8iAM9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P36578	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-348313|ensembl:ENSP00000311430|uniprotkb:P39029|uniprotkb:Q4VBR0|uniprotkb:Q969Z9|uniprotkb:A8K502	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rl4_human(display_long)|uniprotkb:RPL4(gene name)|psi-mi:RPL4(display_short)|uniprotkb:RPL1(gene name synonym)|uniprotkb:60S ribosomal protein L1(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000174444(gene)|ensembl:ENST00000307961(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002136(Ribosomal protein L4/L1e)|interpro:IPR013000(Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site)|interpro:IPR025755|mint:P36578|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|interpro:IPR023574|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6OM0|refseq:NP_000959.2|dip:DIP-27559N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:34il/jyrW0Dqj0eA8GBFgUk05XU9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P52597	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-352986|ensembl:ENSP00000338477|ensembl:ENSP00000349573|ensembl:ENSP00000400433|ensembl:ENSP00000438061|ensembl:ENSP00000507787|ensembl:ENSP00000348345|uniprotkb:Q5T0N2|uniprotkb:Q96AU2|uniprotkb:B3KM84	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:hnrpf_human(display_long)|uniprotkb:HNRNPF(gene name)|psi-mi:HNRNPF(display_short)|uniprotkb:HNRPF(gene name synonym)|uniprotkb:Nucleolin-like protein mcs94-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P52597|rcsb pdb:2HGL|rcsb pdb:2HGM|rcsb pdb:2HGN|rcsb pdb:2KFY|rcsb pdb:2KG0|rcsb pdb:2KG1|rcsb pdb:3TFY|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000169813(gene)|ensembl:ENST00000337970(transcript)|ensembl:ENST00000356053(transcript)|ensembl:ENST00000357065(transcript)|ensembl:ENST00000443950(transcript)|ensembl:ENST00000544000(transcript)|ensembl:ENST00000682386(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001091674.1|refseq:NP_001091675.1|refseq:NP_001091676.1|refseq:NP_001091677.1|refseq:NP_001091678.1|refseq:NP_004957.1|dip:DIP-33145N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:pblzpldZOa5vlZ+zGQY9qyWCxaw9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q9Y3T6	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-2211845|uniprotkb:B7ZLI1|ensembl:ENSP00000265806	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:r3hc1_human(display_long)|uniprotkb:R3HCC1(gene name)|psi-mi:R3HCC1(display_short)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001288579.1|refseq:NP_001129580.2|ensembl:ENSG00000104679(gene)|ensembl:ENST00000265806(transcript)|go:"GO:0003676"(nucleic acid binding)|interpro:IPR001374(Single-stranded nucleic acid binding R3H)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR036867|interpro:IPR039884	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:XxszFTjCHqPsgUb37Zx+OOFAVrw9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P22061-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-353355|ensembl:ENSP00000356348|ensembl:ENSP00000420813	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:p22061-1(display_long)|uniprotkb:PCMT1(gene name)|psi-mi:PCMT1(display_short)|uniprotkb:L-isoaspartyl protein carboxyl methyltransferase(gene name synonym)|uniprotkb:Protein L-isoaspartyl/D-aspartyl methyltransferase(gene name synonym)|uniprotkb:Protein-beta-aspartate methyltransferase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-353343(pimt_human)|ensembl:ENSG00000120265(gene)|ensembl:ENST00000367378(transcript)|ensembl:ENST00000464889(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:wfsjVloc3sqDMXlvFAXQI6Fjilw9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q7Z417	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1210753|intact:EBI-10172018|uniprotkb:A1L3A7|uniprotkb:Q9P2M5|uniprotkb:A1L3A6|ensembl:ENSP00000225388	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:nufp2_human(display_long)|uniprotkb:NUFIP2(gene name)|psi-mi:NUFIP2(display_short)|uniprotkb:KIAA1321(gene name synonym)|uniprotkb:PIG1(orf name)|uniprotkb:FMRP-interacting protein 2(gene name synonym)|uniprotkb:82 kDa FMRP-interacting protein(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 1 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_065823.1|dip:DIP-29023N|ensembl:ENSG00000108256(gene)|ensembl:ENST00000225388(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR032747|mint:Q7Z417	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:zdbkRisveP+8g70umfbEPHTnAgk9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q6NZY4-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1263069|ensembl:ENSP00000488055|ensembl:ENSP00000500728	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q6nzy4-1(display_long)|uniprotkb:ZCCHC8(gene name)|psi-mi:ZCCHC8(display_short)|uniprotkb:TRAMP-like complex RNA-binding factor ZCCHC8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-1263058(zchc8_human)|ensembl:ENSG00000033030(gene)|ensembl:ENST00000633063(transcript)|ensembl:ENST00000672018(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:dtjoaLAUgEGavPmqaJLPnLPHLP49606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q8WWM7-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-948384|ensembl:ENSP00000338718	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q8wwm7-1(display_long)|uniprotkb:A2D-A(isoform synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000168488(gene)|ensembl:ENST00000336783(transcript)|intact:EBI-948363(atx2l_human)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q96RQ3	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-2211703|uniprotkb:Q59ES4|uniprotkb:Q9H959|uniprotkb:Q9NS97|ensembl:ENSP00000265594	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:mcca_human(display_long)|uniprotkb:MCCC1(gene name)|psi-mi:MCCC1(display_short)|uniprotkb:MCCA(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase 1(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha"(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase biotin-containing subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_064551.3|refseq:NP_001280202.1|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR016185(PreATP-grasp-like fold)|mint:Q96RQ3|rcsb pdb:2EJM|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70895|ensembl:ENSG00000078070(gene)|ensembl:ENST00000265594(transcript)|go:"GO:0002169"(3-methylcrotonyl-CoA carboxylase complex, mitochondrial)|go:"GO:0004075"(biotin carboxylase activity)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0006768"(biotin metabolic process)|go:"GO:0009374"(biotin binding)|go:"GO:0016421"(CoA carboxylase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:obze7v7i2yTIIcJjd7laIriNFg89606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P05166	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1371908|uniprotkb:Q16813|uniprotkb:Q96CX0|uniprotkb:B7Z2Z4|ensembl:ENSP00000251654	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:pccb_human(display_long)|uniprotkb:PCCB(gene name)|psi-mi:PCCB(display_short)|uniprotkb:"Propanoyl-CoA:carbon dioxide ligase subunit beta"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_000523.2|refseq:NP_001171485.1|dip:DIP-38244N|mint:P05166|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-71032|interpro:IPR034733|ensembl:ENSG00000114054(gene)|ensembl:ENST00000251654(transcript)|go:"GO:0004658"(propionyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0019626"(short-chain fatty acid catabolic process)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR029045	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:QyhO7MHvNRxNMg7ohwi1xS+VxQE9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P05165	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-2211679|uniprotkb:B4DPF9|uniprotkb:C9JPQ8|uniprotkb:B4DKY8|uniprotkb:Q15979|intact:EBI-2803938|uniprotkb:Q8WXQ7|ensembl:ENSP00000365462	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:pcca_human(display_long)|uniprotkb:PCCA(gene name)|psi-mi:PCCA(display_short)|uniprotkb:"Propanoyl-CoA:carbon dioxide ligase subunit alpha"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_000273.2|refseq:NP_001121164.1|refseq:NP_001171475.1|dip:DIP-57493N|ensembl:ENSG00000175198(gene)|ensembl:ENST00000376285(transcript)|go:"GO:0004658"(propionyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0009374"(biotin binding)|go:"GO:0016421"(CoA carboxylase activity)|go:"GO:0019626"(short-chain fatty acid catabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR041265|mint:P05165|rcsb pdb:2CQY|rcsb pdb:2JKU|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-71032	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:IR3jXR6XjVwD8WRNlN4N5+AOk049606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P62280	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1047710|uniprotkb:B2R4F5|uniprotkb:P04643|uniprotkb:Q498Y6|uniprotkb:Q6IRY0|ensembl:ENSP00000270625	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rs11_human(display_long)|uniprotkb:RPS11(gene name)|psi-mi:RPS11(display_short)|uniprotkb:Small ribosomal subunit protein uS17(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001006.1|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000266(Ribosomal protein S17)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019979|interpro:IPR028333|interpro:IPR032440|mint:P62280|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|go:"GO:0005840"(ribosome)|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|ensembl:ENSG00000142534(gene)|ensembl:ENST00000270625(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6OM0|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:0fqJjtWAuz31VTKt2mbteRoi8vA9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P04259	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-740907|ensembl:ENSP00000252252|uniprotkb:P48669	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:k2c6b_human(display_long)|uniprotkb:Cytokeratin-6B(gene name synonym)|uniprotkb:Keratin-6B(gene name synonym)|uniprotkb:KRT6B(gene name)|psi-mi:KRT6B(display_short)|uniprotkb:K6B(gene name synonym)|uniprotkb:KRTL1(gene name synonym)|uniprotkb:Type-II keratin Kb10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_005546.2|ensembl:ENSG00000185479(gene)|ensembl:ENST00000252252(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0007398"(ectoderm development)|go:"GO:0045095"(keratin filament)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P04259|reactome:R-HSA-6805567|reactome:R-HSA-6809371	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:lFuNGZdQm4pftz53qbflLTyyAaQ9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	intact:EBI-2211147	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	-	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:a8mq54_human(display_short)|psi-mi:EBI-2211147(display_long)|uniprotkb:SOGA2(gene name)|psi-mi:SOGA2(display_short)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	uniprotkb:A8MQ54(uniprot-removed-ac)	psi-mi:"MI:0469"(intact)	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:JYVXj18UYIwgtlgld5mt2gWkMYE9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P60510	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q8IX01-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-949129|ensembl:ENSP00000337926|ensembl:ENSP00000389380|ensembl:ENSP00000472286	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q8ix01-1(display_long)|uniprotkb:SUGP2(gene name)|psi-mi:SUGP2(display_short)|uniprotkb:KIAA0365(gene name synonym)|uniprotkb:Arginine/serine-rich-splicing factor 14(gene name synonym)|uniprotkb:SFRS14(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 14(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000064607(gene)|ensembl:ENST00000337018(transcript)|ensembl:ENST00000452918(transcript)|ensembl:ENST00000601879(transcript)|intact:EBI-949116(sfr14_human)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:hN1zWaoMMufKCQNO9VQ8NPiN0hI9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q9Y580	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-746903|uniprotkb:Q9NUT4|uniprotkb:B2R6K8|ensembl:ENSP00000439918	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rbm7_human(display_long)|uniprotkb:RNA-binding motif protein 7(gene name synonym)|uniprotkb:RBM7(gene name)|psi-mi:RBM7(display_short)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001272974.1|refseq:NP_001272975.1|refseq:NP_001272976.1|refseq:NP_001272977.1|refseq:NP_057174.1|ensembl:ENSG00000076053(gene)|ensembl:ENST00000540163(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0017069"(snRNA binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034500|interpro:IPR035979|mint:Q9Y580|rcsb pdb:2M8H|rcsb pdb:5IQQ|rcsb pdb:5LXR|rcsb pdb:5LXY|dip:DIP-48833N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:d39RjBQTHAVQlOsmrxMX0NCR8CU9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P67775	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P83731	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-353146|ensembl:ENSP00000377640|uniprotkb:P38663|uniprotkb:Q6IBS3|uniprotkb:B2R4Y3	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rl24_human(display_long)|uniprotkb:RPL24(gene name)|psi-mi:RPL24(display_short)|uniprotkb:60S ribosomal protein L30(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL24(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	go:"GO:0016020"(membrane)|go:"GO:0021554"(optic nerve development)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR000988(Ribosomal protein L24e)|interpro:IPR011017(TRASH)|interpro:IPR023442|interpro:IPR038630|mint:P83731|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZMI|rcsb pdb:6ZME|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000114391(gene)|ensembl:ENST00000394077(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0010458"(exit from mitosis)|refseq:NP_000977.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:+Ah+YGgcjqOsk5ZS1HZUMQA/Of89606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P04264	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-298429|uniprotkb:Q14720|uniprotkb:Q6GSJ0|uniprotkb:B2RA01|uniprotkb:Q9H298|ensembl:ENSP00000252244|uniprotkb:P85925|uniprotkb:P86104	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:k2c1_human(display_long)|uniprotkb:KRT1(gene name)|psi-mi:KRT1(display_short)|uniprotkb:KRTA(gene name synonym)|uniprotkb:Keratin-1(gene name synonym)|uniprotkb:Cytokeratin-1(gene name synonym)|uniprotkb:67 kDa cytokeratin(gene name synonym)|uniprotkb:Hair alpha protein(gene name synonym)|uniprotkb:Type-II keratin Kb1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_006112.3|ensembl:ENSG00000167768(gene)|ensembl:ENST00000252244(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042730"(fibrinolysis)|go:"GO:0045095"(keratin filament)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR032449|interpro:IPR039008|mint:P04264|rcsb pdb:4ZRY|rcsb pdb:6E2J|rcsb pdb:6UUI|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:TeAC3i2hWTS2lgXT0i4agp9nv349606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P17987	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P14923	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-702484|uniprotkb:Q15093|intact:EBI-988999|intact:EBI-744449|uniprotkb:Q9HCX9|uniprotkb:Q15151|uniprotkb:Q7L3S5|uniprotkb:Q86W21|uniprotkb:Q9BWC4|ensembl:ENSP00000311113|ensembl:ENSP00000377507|ensembl:ENSP00000377508	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:plak_human(display_long)|uniprotkb:JUP(gene name)|psi-mi:JUP(display_short)|uniprotkb:DP3(gene name synonym)|uniprotkb:CTNNG(gene name synonym)|uniprotkb:Desmoplakin-3(gene name synonym)|uniprotkb:Desmoplakin III(gene name synonym)|uniprotkb:Catenin gamma(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_002221.1|refseq:NP_068831.1|refseq:XP_011523055.1|refseq:XP_011523057.1|refseq:XP_011523058.1|refseq:XP_011523059.1|refseq:XP_011523060.1|refseq:XP_006721936.1|refseq:XP_006721937.1|refseq:XP_006721938.1|refseq:XP_006721941.1|refseq:XP_016880079.1|dip:DIP-36235N|ensembl:ENSG00000173801(gene)|ensembl:ENST00000310706(transcript)|ensembl:ENST00000393930(transcript)|ensembl:ENST00000393931(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002159"(desmosome assembly)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030057"(desmosome)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043588"(skin development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071603"(endothelial cell-cell adhesion)|go:"GO:0071665"(gamma-catenin-TCF7L2 complex)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR030461|mint:P14923|rcsb pdb:3IFQ|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:qOBUlbifyKUk1xF0Zr9jZPkZozc9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:O94761	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-722861|uniprotkb:Q3Y424|uniprotkb:Q96DW2|uniprotkb:A0A087WZ30|uniprotkb:Q96F55|ensembl:ENSP00000482313	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:recq4_human(display_long)|uniprotkb:RecQ protein-like 4(gene name synonym)|uniprotkb:RTS(gene name synonym)|uniprotkb:RECQL4(gene name)|psi-mi:RECQL4(display_short)|uniprotkb:RECQ4(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_004251.3|ensembl:ENSG00000160957(gene)|ensembl:ENST00000617875(transcript)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0016020"(membrane)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021110|interpro:IPR027417|rcsb pdb:2KMU|rcsb pdb:5LST|dip:DIP-48475N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:FMX8OqwUNPdPfNL6EsLucTQCNfQ9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P35908	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1247312|uniprotkb:Q4VAQ2|ensembl:ENSP00000310861	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:k22e_human(display_long)|uniprotkb:KRT2(gene name)|psi-mi:KRT2(display_short)|uniprotkb:KRT2A(gene name synonym)|uniprotkb:KRT2E(gene name synonym)|uniprotkb:Cytokeratin-2e(gene name synonym)|uniprotkb:Keratin-2e(gene name synonym)|uniprotkb:Type-II keratin Kb2(gene name synonym)|uniprotkb:Keratin-2 epidermis(gene name synonym)|uniprotkb:Epithelial keratin-2e(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_000414.2|ensembl:ENSG00000172867(gene)|ensembl:ENST00000309680(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0003334"(keratinocyte development)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0031424"(keratinization)|go:"GO:0032980"(keratinocyte activation)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0045095"(keratin filament)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045684"(positive regulation of epidermis development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P35908|reactome:R-HSA-6805567|reactome:R-HSA-6809371|go:"GO:0051546"(keratinocyte migration)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:T7LeB8nkZzNjUb8DWdkxbrl5f789606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P05412	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-852823|uniprotkb:Q96G93|uniprotkb:Q6FHM7|ensembl:ENSP00000360266|ensembl:ENSP00000503132	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:jun_human(display_long)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short)|uniprotkb:Activator protein 1(gene name synonym)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)|uniprotkb:p39(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_002219.1|ensembl:ENSP00000360266|ensembl:ENSP00000503132|dip:DIP-5961N|ensembl:ENSG00000177606(gene)|ensembl:ENST00000371222(transcript)|ensembl:ENST00000678696(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009314"(response to radiation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051365"(cellular response to potassium ion starvation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR015558(c-Jun Transcription Factor)|mint:P05412|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1JNM|rcsb pdb:1JUN|rcsb pdb:1S9K|rcsb pdb:1T2K|rcsb pdb:5FV8|rcsb pdb:5T01|rcsb pdb:6Y3V|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-6796648|reactome:R-HSA-8862803|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9673324	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:zAVYwedHKKdvPPGttBP4XZkbCXA9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P50991	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P62829	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-353303|uniprotkb:P23131|uniprotkb:Q3SWV7|uniprotkb:P24048|uniprotkb:Q29246|uniprotkb:Q6P5S1|ensembl:ENSP00000377865|ensembl:ENSP00000420311	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rl23_human(display_long)|uniprotkb:RPL23(gene name)|psi-mi:RPL23(display_short)|uniprotkb:60S ribosomal protein L17(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL14(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|reactome:R-HSA-9010553|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|refseq:NP_000969.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000218(Ribosomal protein L14b/L23e)|interpro:IPR019972|interpro:IPR036853|mint:P62829|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|ensembl:ENSG00000125691(gene)|ensembl:ENST00000394332(transcript)|ensembl:ENST00000479035(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005730"(nucleolus)|dip:DIP-33156N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:TiSVU2W4+lkwf12eb4+vG6IFlZA9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P47756-2	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-353608|ensembl:ENSP00000264202	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:p47756-2(display_long)|uniprotkb:CAPZB(gene name)|psi-mi:CAPZB(display_short)|uniprotkb:CapZ beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-353595(capzb_human)|ensembl:ENSG00000077549(gene)|ensembl:ENST00000264202(transcript)|uniprotkb:P47756-2(isoform-parent)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:48IQ1CJkjL9DdUW66uFlFKhRWxo9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P61978-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-431928|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244-1	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:p61978-1(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000165119(gene)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|intact:EBI-304185(hnrpk_human)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P48643	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q8N163-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1021318|ensembl:ENSP00000310670|ensembl:ENSP00000373930	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q8n163-1(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-355410(q8n163_human)|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:O14654	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356594|ensembl:ENSP00000505547	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P49411	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P38646	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P31151	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-357520|uniprotkb:Q6FGE3|uniprotkb:Q5SY67|uniprotkb:Q9H1E2|ensembl:ENSP00000357711|ensembl:ENSP00000357712	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:s10a7_human(display_long)|uniprotkb:S100A7(gene name)|psi-mi:S100A7(display_short)|uniprotkb:PSOR1(gene name synonym)|uniprotkb:S100A7C(gene name synonym)|uniprotkb:S100 calcium-binding protein A7(gene name synonym)|uniprotkb:Psoriasin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000143556(gene)|ensembl:ENST00000368722(transcript)|ensembl:ENST00000368723(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045087"(innate immune response)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051238"(sequestering of metal ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071624"(positive regulation of granulocyte chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028477|interpro:IPR034325|mint:P31151|rcsb pdb:1PSR|rcsb pdb:2PSR|rcsb pdb:2WND|rcsb pdb:2WOR|rcsb pdb:2WOS|rcsb pdb:3PSR|rcsb pdb:4AQJ|reactome:R-HSA-6798695|reactome:R-HSA-6799990|refseq:NP_002954.2	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:/v8+XQ7rCMTYzq9k/KqjcSm/G0A9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P11498	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-2211322|uniprotkb:Q16705|uniprotkb:B4DN00|ensembl:ENSP00000377527|ensembl:ENSP00000377530|ensembl:ENSP00000377532|ensembl:ENSP00000435905|ensembl:ENSP00000498302|ensembl:ENSP00000498406|ensembl:ENSP00000498994	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:pyc_human(display_long)|uniprotkb:PC(gene name)|psi-mi:PC(display_short)|uniprotkb:Pyruvic carboxylase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:XP_011543388.1|refseq:XP_016873357.1|refseq:XP_016873358.1|refseq:XP_016873359.1|refseq:XP_016873360.1|refseq:XP_016873361.1|refseq:NP_000911.2|refseq:NP_001035806.1|refseq:NP_071504.2|refseq:XP_005274088.1|refseq:XP_005274089.1|refseq:XP_006718641.1|dip:DIP-46372N|ensembl:ENSG00000173599(gene)|ensembl:ENST00000393955(transcript)|ensembl:ENST00000393958(transcript)|ensembl:ENST00000393960(transcript)|ensembl:ENST00000529047(transcript)|ensembl:ENST00000651036(transcript)|ensembl:ENST00000651854(transcript)|ensembl:ENST00000652125(transcript)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0009374"(biotin binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0042802"(identical protein binding)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR001882(Biotin-binding site)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|mint:P11498|rcsb pdb:3BG3|rcsb pdb:3BG9|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70263	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:0xXv1wxe0AC1EO7wxSDVhBpHCUU9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q9HCC0-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-2211442|ensembl:ENSP00000343657	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q9hcc0-1(display_long)|uniprotkb:MCCC2(gene name)|psi-mi:MCCC2(display_short)|uniprotkb:MCCB(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase 2(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-2211296(isoform-parent)|ensembl:ENSG00000131844(gene)|ensembl:ENST00000340941(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:5NkqDKqdX1wHsbqXW7v5+/Gld109606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P78371	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q99832	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P15924-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-355054|ensembl:ENSP00000369129	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:p15924-1(display_long)|uniprotkb:DP1(isoform synonym)|uniprotkb:DSP(gene name)|psi-mi:DSP(display_short)|uniprotkb:250/210 kDa paraneoplastic pemphigus antigen(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-355041(desp_human)|ensembl:ENSG00000096696(gene)|ensembl:ENST00000379802(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:enapEqSoyTSLfPEQUAopkGpdxbo9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q8IX90-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1773985|ensembl:ENSP00000319417	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q8ix90-1(display_long)|uniprotkb:SKA3(gene name)|psi-mi:SKA3(display_short)|uniprotkb:C13orf3(gene name synonym)|uniprotkb:RAMA1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-1773976(isoform-parent)|ensembl:ENSG00000165480(gene)|ensembl:ENST00000314759(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:F3lm7ntNHVutZ+X66pTMEfyyJ+E9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P51610-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-396188|ensembl:ENSP00000309555	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:p51610-1(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:HFC1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-396176(hcfc1_human)|ensembl:ENSG00000172534(gene)|ensembl:ENST00000310441(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P42285	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-347612|uniprotkb:Q2M386|uniprotkb:Q6MZZ8|uniprotkb:Q6P170|uniprotkb:Q8N5R0|uniprotkb:Q8TAG2|ensembl:ENSP00000230640	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:mtrex_human(display_long)|uniprotkb:MTREX(gene name)|psi-mi:MTREX(display_short)|uniprotkb:DOB1(gene name synonym)|uniprotkb:KIAA0052(gene name synonym)|uniprotkb:MTR4(gene name synonym)|uniprotkb:SKIV2L2(gene name synonym)|uniprotkb:Superkiller viralicidic activity 2-like 2(gene name synonym)|uniprotkb:TRAMP-like complex helicase(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DOB1(gene name synonym)|uniprotkb:ATP-dependent RNA helicase SKIV2L2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_056175.3|ensembl:ENSG00000039123(gene)|ensembl:ENST00000230640(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0031499"(TRAMP complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|mint:P42285|rcsb pdb:6C90|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6IEG|rcsb pdb:6IEH|rcsb pdb:6RO1|reactome:R-HSA-6791226|reactome:R-HSA-72163	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:bQdFDddFhetSp+CJ1S7Q5cm+g0k9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q9H0K1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1181664|uniprotkb:A8K5B8|uniprotkb:O94878|uniprotkb:Q17RV0|uniprotkb:Q6AZE2|uniprotkb:Q76N03|uniprotkb:Q8NCV7|uniprotkb:Q96CZ8|uniprotkb:B0YJ94|ensembl:ENSP00000305976	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:sik2_human(display_long)|uniprotkb:SIK2(gene name)|psi-mi:SIK2(display_short)|uniprotkb:Qin-induced kinase(gene name synonym)|uniprotkb:SNF1LK2(gene name synonym)|uniprotkb:KIAA0781(gene name synonym)|uniprotkb:QIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SNF1-like kinase 2(gene name synonym)|uniprotkb:Salt-inducible kinase 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_056006.1|ensembl:ENSG00000170145(gene)|ensembl:ENST00000304987(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017090(Serine/threonine-protein kinase, SNF1-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR034672	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:h9FQ/a2qA7FtWC0yWI1pK4LTZtA9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P18621	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-726937|uniprotkb:Q6NZ54|uniprotkb:Q7M4M5|uniprotkb:Q3KQW2|uniprotkb:B2R4H3|uniprotkb:B4E3C2|uniprotkb:B5ME31|uniprotkb:J3QL51|ensembl:ENSP00000462023|ensembl:ENSP00000462385|ensembl:ENSP00000463842|ensembl:ENSP00000480555|ensembl:ENSP00000482577	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rl17_human(display_long)|uniprotkb:60S ribosomal protein L23(gene name synonym)|uniprotkb:PD-1(gene name synonym)|uniprotkb:RPL17(gene name)|psi-mi:RPL17(display_short)|uniprotkb:Large ribosomal subunit protein uL22(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_000976.1|refseq:NP_001030178.1|refseq:NP_001186269.1|refseq:NP_001186270.1|refseq:NP_001186271.1|refseq:NP_001186272.1|refseq:NP_001186273.1|refseq:NP_001186274.1|ensembl:ENSG00000265681(gene)|ensembl:ENST00000579248(transcript)|ensembl:ENST00000579408(transcript)|ensembl:ENST00000580261(transcript)|ensembl:ENST00000618613(transcript)|ensembl:ENST00000618619(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001063(Ribosomal protein L22/L17)|interpro:IPR005721(Ribosomal protein L22/L17, eukaryotic/archaeal)|interpro:IPR018260|interpro:IPR036394|mint:P18621|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:/i0W3WoeFakz+8R/YMYf2JQZytI9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P62263	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-352783|ensembl:ENSP00000311028|ensembl:ENSP00000385425|uniprotkb:P06366|uniprotkb:Q5BJI0|uniprotkb:B2R5G5|uniprotkb:D3DQG5|ensembl:ENSP00000385958|ensembl:ENSP00000428509	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rs14_human(display_long)|uniprotkb:RPS14(gene name)|psi-mi:RPS14(display_short)|uniprotkb:Small ribosomal subunit protein uS11(gene name synonym)|uniprotkb:PRO2640(orf name)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000164587(gene)|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001020242.1|refseq:NP_005608.1|refseq:NP_001020241.1|ensembl:ENST00000312037(transcript)|ensembl:ENST00000401695(transcript)|ensembl:ENST00000407193(transcript)|ensembl:ENST00000521466(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR001971(Ribosomal protein S11)|interpro:IPR018102|interpro:IPR036967|mint:P62263|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZXD	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:ee3bJ5JYFaZXyCCRG9Wooopyz2o9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P02533	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-702178|uniprotkb:Q14715|uniprotkb:Q53XY3|uniprotkb:Q9BUE3|uniprotkb:Q9UBN2|uniprotkb:Q9UBN3|uniprotkb:Q9UCY4|ensembl:ENSP00000167586	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:k1c14_human(display_long)|uniprotkb:Cytokeratin-14(gene name synonym)|uniprotkb:KRT14(gene name)|psi-mi:KRT14(display_short)|uniprotkb:Keratin-14(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_000517.2|dip:DIP-33874N|ensembl:ENSG00000186847(gene)|ensembl:ENST00000167586(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0007568"(aging)|go:"GO:0008544"(epidermis development)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042633"(hair cycle)|go:"GO:0045095"(keratin filament)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0045178"(basal part of cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990254"(keratin filament binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P02533|rcsb pdb:3TNU|rcsb pdb:6JFV|reactome:R-HSA-446107|reactome:R-HSA-6805567|reactome:R-HSA-6809371	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:IO1k6S8FB65jQr4GNwhKuxZ1ohg9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P13645	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-465144|ensembl:ENSP00000269576|uniprotkb:Q14664|uniprotkb:Q8N175	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:k1c10_human(display_long)|uniprotkb:KRT10(gene name)|psi-mi:KRT10(display_short)|uniprotkb:Cytokeratin-10(gene name synonym)|uniprotkb:KPP(gene name synonym)|uniprotkb:Keratin-10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000186395(gene)|ensembl:ENST00000269576(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0045684"(positive regulation of epidermis development)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P13645|rcsb pdb:3ASW|rcsb pdb:4F1Z|rcsb pdb:4ZRY|rcsb pdb:6E2J|rcsb pdb:6EC0|rcsb pdb:6UUI|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_000412.3	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:z100yyq3b63P0ARy2lE2ELyJeik9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P11021	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P40227	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:O00571	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q9NUC0	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1773811|uniprotkb:B2RD32|ensembl:ENSP00000355979|ensembl:ENSP00000486369	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:srtd4_human(display_long)|uniprotkb:SERTAD4(gene name)|psi-mi:SERTAD4(display_short)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_062551.1|ensembl:ENSG00000082497(gene)|ensembl:ENSG00000281230(gene)|ensembl:ENST00000367012(transcript)|ensembl:ENST00000630425(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR009263(SERTA)|interpro:IPR029708	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:us8AIu8sIAtj+ZOqwAH2vzWE0ik9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P35527	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356382|uniprotkb:O00109|uniprotkb:Q0IJ47|uniprotkb:Q14665|ensembl:ENSP00000246662	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:k1c9_human(display_long)|uniprotkb:KRT9(gene name)|psi-mi:KRT9(display_short)|uniprotkb:Keratin-9(gene name synonym)|uniprotkb:Cytokeratin-9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_000217.2|ensembl:ENSG00000171403(gene)|ensembl:ENST00000246662(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0043588"(skin development)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P35527|reactome:R-HSA-6805567|reactome:R-HSA-6809371	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:m4EXfxbK2t1/EmI04YODKTJ02Zw9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P30153	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P42167	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-455283|uniprotkb:Q14861|ensembl:ENSP00000450627|uniprotkb:A2T926	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:lap2b_human(display_long)|uniprotkb:Thymopoietin-related peptide isoforms beta/gamma(gene name synonym)|uniprotkb:Thymopoietin, isoforms beta/gamma(gene name synonym)|uniprotkb:TMPO(gene name)|psi-mi:TMPO(display_short)|uniprotkb:LAP2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001294904.1|refseq:NP_001027454.1|refseq:NP_001027455.1|ensembl:ENSG00000120802(gene)|ensembl:ENST00000556029(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|mint:P42167|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|dip:DIP-43686N|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:S2mYrSugx0Ms4vhw/vYYH/SthOw9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P60953	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|uniprotkb:Q9UDI2|ensembl:ENSP00000341072|ensembl:ENSP00000383118|ensembl:ENSP00000497733|ensembl:ENSP00000499457|ensembl:ENSP00000499612	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007097"(nuclear migration)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016020"(membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030141"(secretory granule)|go:"GO:0030175"(filopodium)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030496"(midbody)|go:"GO:0005886"(plasma membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0005911"(cell-cell junction)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007015"(actin filament organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0038189"(neuropilin signaling pathway)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0031996"(thioesterase binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0032427"(GBD domain binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|ensembl:ENSG00000070831(gene)|ensembl:ENST00000344548(transcript)|ensembl:ENST00000400259(transcript)|ensembl:ENST00000648594(transcript)|ensembl:ENST00000656825(transcript)|ensembl:ENST00000662562(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000322"(storage vacuole)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0060661"(submandibular salivary gland formation)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072384"(organelle transport along microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090135"(actin filament branching)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|go:"GO:0046847"(filopodium assembly)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0048664"(neuron fate determination)|go:"GO:0051233"(spindle midzone)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0060047"(heart contraction)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|dip:DIP-31097N|reactome:R-HSA-983231|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1AN0|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|rcsb pdb:1A4R|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q15323	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-948001|uniprotkb:Q9UE12|ensembl:ENSP00000251645|ensembl:ENSP00000460739	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:k1h1_human(display_long)|uniprotkb:Hair keratin, type I Ha1(gene name synonym)|uniprotkb:Keratin-31(gene name synonym)|uniprotkb:KRT31(gene name)|psi-mi:KRT31(display_short)|uniprotkb:HHA1(gene name synonym)|uniprotkb:HKA1(gene name synonym)|uniprotkb:KRTHA1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_002268.2|ensembl:ENSG00000094796(gene)|ensembl:ENSG00000262993(gene)|ensembl:ENST00000251645(transcript)|ensembl:ENST00000573281(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:ur97LEvtqaqu3wh7iaX4HhN163k9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q3MHD2-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1883882|ensembl:ENSP00000293406|ensembl:ENSP00000466718	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q3mhd2-1(display_long)|uniprotkb:LSM12(gene name)|psi-mi:LSM12(display_short)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-725133(isoform-parent)|ensembl:ENST00000293406(transcript)|ensembl:ENST00000591247(transcript)|ensembl:ENSG00000161654(gene)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:SY9HUXXLZyXhttFb+AXkMh0QOek9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:O75400-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-473306	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:o75400-1(display_long)|uniprotkb:PRPF40A(gene name)|psi-mi:PRPF40A(display_short)|uniprotkb:FBP11(gene name synonym)|uniprotkb:FLAF1(gene name synonym)|uniprotkb:FNBP3(gene name synonym)|uniprotkb:HIP10(gene name synonym)|uniprotkb:HYPA(gene name synonym)|uniprotkb:Fas ligand-associated factor 1(gene name synonym)|uniprotkb:Formin-binding protein 11(gene name synonym)|uniprotkb:Formin-binding protein 3(gene name synonym)|uniprotkb:Huntingtin yeast partner A(gene name synonym)|uniprotkb:Huntingtin-interacting protein 10(gene name synonym)|uniprotkb:Huntingtin-interacting protein A(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-6(gene name synonym)|uniprotkb:HSPC225(orf name)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-473291(fnbp3_human)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:XgnBshjHK5u08HROtUS9Zr2Ot809606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q14525	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1049638|uniprotkb:O76010|ensembl:ENSP00000251646|ensembl:ENSP00000459509	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:kt33b_human(display_long)|uniprotkb:KRTHA3B(gene name synonym)|uniprotkb:Hair keratin, type I Ha3-II(gene name synonym)|uniprotkb:Keratin-33B(gene name synonym)|uniprotkb:KRT33B(gene name)|psi-mi:KRT33B(display_short)|uniprotkb:HHA3-II(gene name synonym)|uniprotkb:HKA3B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_002270.1|ensembl:ENSG00000131738(gene)|ensembl:ENSG00000263012(gene)|ensembl:ENST00000251646(transcript)|ensembl:ENST00000570596(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0007568"(aging)|go:"GO:0042633"(hair cycle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:Q14525|reactome:R-HSA-6805567|reactome:R-HSA-6809371	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:TDqltAJBdpwMGaQsl0Lznc8Y7Ns9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P47756-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-353604|ensembl:ENSP00000364284|ensembl:ENSP00000501528	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:p47756-1(display_long)|uniprotkb:CAPZB(gene name)|psi-mi:CAPZB(display_short)|uniprotkb:CapZ beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-353595(capzb_human)|ensembl:ENST00000375142(transcript)|ensembl:ENST00000674432(transcript)|ensembl:ENSG00000077549(gene)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:qRXsrB2fLT1DMVIVRWKFYe4Aln49606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P02768-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1220667|ensembl:ENSP00000295897	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:p02768-1(display_long)|uniprotkb:ALB(gene name)|psi-mi:ALB(display_short)|uniprotkb:GIG20(orf name)|uniprotkb:GIG42(orf name)|uniprotkb:PRO0903(orf name)|uniprotkb:PRO1708(orf name)|uniprotkb:PRO2044(orf name)|uniprotkb:PRO2619(orf name)|uniprotkb:PRO2675(orf name)|uniprotkb:UNQ696/PRO1341(orf name)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-714423(albu_human)|ensembl:ENSG00000163631(gene)|ensembl:ENST00000295897(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:kjtn5mBsCZz/NRkcyW5k3ZWeJBU9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P33992	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-359410|ensembl:ENSP00000216122|uniprotkb:O60785|uniprotkb:Q14578|uniprotkb:Q9BTJ4|uniprotkb:Q9BWL8	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:mcm5_human(display_long)|uniprotkb:MCM5(gene name)|psi-mi:MCM5(display_short)|uniprotkb:CDC46(gene name synonym)|uniprotkb:CDC46 homolog(gene name synonym)|uniprotkb:P1-CDC46(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000100297(gene)|ensembl:ENST00000216122(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33992|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|refseq:NP_006730.2|reactome:R-HSA-69052|reactome:R-HSA-68962|dip:DIP-27578N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:WjJ4lSpADQFtwT0WnumbRHl/lPw9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P05387	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-352813|ensembl:ENSP00000322419|ensembl:ENSP00000431240|uniprotkb:Q6FG96	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rla2_human(display_long)|uniprotkb:RPLP2(gene name)|psi-mi:RPLP2(display_short)|uniprotkb:RPP2(gene name synonym)|uniprotkb:D11S2243E(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-44(gene name synonym)|uniprotkb:Large ribosomal subunit protein P2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000177600(gene)|ensembl:ENST00000321153(transcript)|ensembl:ENST00000530797(transcript)|go:"GO:0002182"(cytoplasmic translational elongation)|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72689|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|mint:P05387|rcsb pdb:1S4J|rcsb pdb:2JDL|rcsb pdb:2LBF|rcsb pdb:2W1O|rcsb pdb:4BEH|rcsb pdb:4V6X|rcsb pdb:5DDZ|rcsb pdb:5GU4|go:"GO:0003735"(structural constituent of ribosome)|reactome:R-HSA-156827|reactome:R-HSA-156902|refseq:NP_000995.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:IBI+x82JJYg66MPhGKw1/pI/bQA9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q9Y5Z7	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-592728|uniprotkb:B2R8Q5|uniprotkb:C0H5X3|ensembl:ENSP00000229330	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:hcfc2_human(display_long)|uniprotkb:C2 factor(gene name synonym)|uniprotkb:HCFC2(gene name)|psi-mi:HCFC2(display_short)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_037452.1|ensembl:ENSG00000111727(gene)|ensembl:ENST00000229330(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016032"(viral process)|go:"GO:0016604"(nuclear body)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037932|interpro:IPR043536|mint:Q9Y5Z7	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:ytE7Aid9JO9RWsRpJPpBbylLRXo9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P07355	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P68363	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P07900	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|ensembl:ENSP00000216281|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	go:"GO:0009409"(response to cold)|go:"GO:0016020"(membrane)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|ensembl:ENST00000216281(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000080824(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043335"(protein unfolding)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1UY8|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2BYH|rcsb pdb:2VCJ|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3B24|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5LO1|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6CYH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7LSZ|rcsb pdb:7LT0|reactome:R-HSA-1227986|reactome:R-HSA-1236382|rcsb pdb:6TN4|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9665233|reactome:R-HSA-9664565|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3K99|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:3T0H|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:4YKZ|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|refseq:NP_001017963.2|refseq:NP_005339.3|dip:DIP-27595N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q9BXL8	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1773949|uniprotkb:Q8TB18|uniprotkb:Q9NWK7|ensembl:ENSP00000337226|ensembl:ENSP00000376369	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:cdca4_human(display_long)|uniprotkb:CDCA4(gene name)|psi-mi:CDCA4(display_short)|uniprotkb:HEPP(gene name synonym)|uniprotkb:Hematopoietic progenitor protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_060425.2|refseq:NP_663747.1|ensembl:ENSG00000170779(gene)|ensembl:ENST00000336219(transcript)|ensembl:ENST00000392590(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0048096"|interpro:IPR009263(SERTA)|mint:Q9BXL8	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:sxwZ0Yw0uG+MjnhKtVv+8PHvPCo9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P62158	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P52907	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-355586|uniprotkb:Q53FQ6|uniprotkb:Q6FHD5|ensembl:ENSP00000263168	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:caza1_human(display_long)|uniprotkb:CAPZA1(gene name)|psi-mi:CAPZA1(display_short)|uniprotkb:CapZ alpha-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_006126.1|ensembl:ENSG00000116489(gene)|ensembl:ENST00000263168(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071203"(WASH complex)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P52907|rcsb pdb:1MQ1|rcsb pdb:1MWN|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-8950505|reactome:R-HSA-9662360|reactome:R-HSA-983231	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:97S4WPtjgt4MDLoptRhQ2yH8UNE9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P46013-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-876379|ensembl:ENSP00000357643	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:p46013-1(display_long)|uniprotkb:MKI67(gene name)|psi-mi:MKI67(display_short)|uniprotkb:Antigen identified by monoclonal antibody Ki-67(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-876367(ki67_human)|ensembl:ENSG00000148773(gene)|ensembl:ENST00000368654(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:kyrLLOv4HSqah1Y6HtzebG978Kw9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P60709	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P31943	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P10809	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-352528|ensembl:ENSP00000340019|ensembl:ENSP00000373620|ensembl:ENSP00000396460|ensembl:ENSP00000402478|ensembl:ENSP00000412227|ensembl:ENSP00000412717|ensembl:ENSP00000414446|ensembl:ENSP00000503139|ensembl:ENSP00000503894|uniprotkb:Q38L19|uniprotkb:B2R5M6|uniprotkb:Q9UCR6|uniprotkb:B7Z712	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:ch60_human(display_long)|uniprotkb:HSPD1(gene name)|psi-mi:HSPD1(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:P60 lymphocyte protein(gene name synonym)|uniprotkb:HuCHA60(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_002147.2|refseq:NP_955472.1|ensembl:ENSG00000144381(gene)|ensembl:ENST00000345042(transcript)|ensembl:ENST00000388968(transcript)|ensembl:ENST00000418022(transcript)|ensembl:ENST00000426480(transcript)|ensembl:ENST00000428204(transcript)|ensembl:ENST00000439605(transcript)|ensembl:ENST00000452200(transcript)|ensembl:ENST00000677913(transcript)|ensembl:ENST00000678761(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051604"(protein maturation)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P10809|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|rcsb pdb:7AZP|reactome:R-HSA-1268020|reactome:R-HSA-8869496|dip:DIP-58N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:syB2vt66Cpr2mJROfbxoPevoiRE9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P08670	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-353844|uniprotkb:Q15867|uniprotkb:Q15868|uniprotkb:Q15869|uniprotkb:Q548L2|uniprotkb:Q6LER9|uniprotkb:Q8N850|uniprotkb:Q96ML2|uniprotkb:Q9NTM3|uniprotkb:B0YJC2|intact:EBI-3442369|uniprotkb:D3DRU4|ensembl:ENSP00000224237|ensembl:ENSP00000446007	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:vime_human(display_long)|uniprotkb:VIM(gene name)|psi-mi:VIM(display_short)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_003371.2|ensembl:ENSG00000026025(gene)|ensembl:ENST00000224237(transcript)|ensembl:ENST00000544301(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027699|interpro:IPR039008|mint:P08670|rcsb pdb:1GK4|rcsb pdb:1GK6|rcsb pdb:1GK7|rcsb pdb:3G1E|rcsb pdb:3KLT|rcsb pdb:3S4R|rcsb pdb:3SSU|rcsb pdb:3SWK|rcsb pdb:3TRT|rcsb pdb:3UF1|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4YPC|rcsb pdb:4YV3|rcsb pdb:5WHF|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6BIR|rcsb pdb:6YXK|reactome:R-HSA-264870|reactome:R-HSA-390522|reactome:R-HSA-6785807|reactome:R-HSA-9013422|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|refseq:XP_006717563.1|dip:DIP-32507N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:GhAhVuXMNxi6P5J0CfNi5l9bjRk9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q7Z2W4-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-922555|ensembl:ENSP00000242351	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q7z2w4-1(display_long)|uniprotkb:ZC3HAV1(gene name)|psi-mi:ZC3HAV1(display_short)|uniprotkb:ZC3HDC2(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger antiviral protein(gene name synonym)|uniprotkb:PRO1677(orf name)|uniprotkb:ZAPL(isoform synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 13(gene name synonym)|uniprotkb:Inactive Poly [ADP-ribose] polymerase 13(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-922540(zcc2_human)|ensembl:ENSG00000105939(gene)|ensembl:ENST00000242351(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:iJy4W/YX/vVXGbFd+GnfoKlo8aA9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P68104	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q14533	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-739648|uniprotkb:Q14846|uniprotkb:Q16274|uniprotkb:Q8WU52|uniprotkb:Q9BR74|uniprotkb:Q17R48|ensembl:ENSP00000369349	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:krt81_human(display_long)|uniprotkb:Type II hair keratin Hb1(gene name synonym)|uniprotkb:ghHKb1(gene name synonym)|uniprotkb:Keratin-81(gene name synonym)|uniprotkb:Type-II keratin Kb21(gene name synonym)|uniprotkb:Hair keratin K2.9(gene name synonym)|uniprotkb:KRT81(gene name)|psi-mi:KRT81(display_short)|uniprotkb:KRTHB1(gene name synonym)|uniprotkb:MLN137(gene name synonym)|uniprotkb:Keratin, hair, basic, 1(gene name synonym)|uniprotkb:Metastatic lymph node 137 gene protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_002272.2|ensembl:ENST00000327741(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR003054(Type II keratin)|ensembl:ENSG00000205426(gene)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:Y/1YhLCN54gK8DZQyc4OqfNDwAs9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P78386	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1049371|uniprotkb:Q9NSB1|ensembl:ENSP00000257901	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:krt85_human(display_long)|uniprotkb:Type II hair keratin Hb5(gene name synonym)|uniprotkb:Keratin-85(gene name synonym)|uniprotkb:Hair keratin K2.12(gene name synonym)|uniprotkb:KRT85(gene name)|psi-mi:KRT85(display_short)|uniprotkb:KRTHB5(gene name synonym)|uniprotkb:Type-II keratin Kb25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001287739.1|refseq:NP_002274.1|ensembl:ENSG00000135443(gene)|ensembl:ENST00000257901(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0045095"(keratin filament)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:O+5NoIWK84IGOos3h32HHMjZE889606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q9HAV7	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1043499|uniprotkb:Q549M6|uniprotkb:B2R783|ensembl:ENSP00000264954	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:grpe1_human(display_long)|uniprotkb:Mt-GrpE#1(gene name synonym)|uniprotkb:HMGE(gene name synonym)|uniprotkb:GRPEL1(gene name)|psi-mi:GRPEL1(display_short)|uniprotkb:GREPEL1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000109519(gene)|ensembl:ENST00000264954(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR000740(GrpE nucleotide exchange factor)|interpro:IPR009012(GrpE nucleotide exchange factor, head)|interpro:IPR013805(GrpE nucleotide exchange factor, coiled-coil)|mint:Q9HAV7|reactome:R-HSA-1268020|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_079472.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:OWuX4gnZBzxgv0arSEKY9KyZZ+o9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P06702	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1055001|uniprotkb:Q6FGA1|uniprotkb:Q9NYM0|uniprotkb:Q9UCJ1|uniprotkb:D3DV36|ensembl:ENSP00000357727	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:s10a9_human(display_long)|uniprotkb:S100 calcium-binding protein A9(gene name synonym)|uniprotkb:Calgranulin-B(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 14(gene name synonym)|uniprotkb:Leukocyte L1 complex heavy chain(gene name synonym)|uniprotkb:Calprotectin L1H subunit(gene name synonym)|uniprotkb:S100A9(gene name)|psi-mi:S100A9(display_short)|uniprotkb:CAGB(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:MRP14(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_002956.1|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5I8N|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENSG00000163220(gene)|ensembl:ENST00000368738(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0035821"(modulation of process of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045113"(regulation of integrin biosynthetic process)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|mint:P06702|rcsb pdb:1IRJ|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030054"(cell junction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|dip:DIP-1166N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:IGnX4DSnv8xMr5pY4T7X7vYos5A9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P26196	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:O00763-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-2211783|ensembl:ENSP00000341044|ensembl:ENSP00000367079	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:o00763-1(display_long)|uniprotkb:ACACB(gene name)|psi-mi:ACACB(display_short)|uniprotkb:ACC2(gene name synonym)|uniprotkb:ACCB(gene name synonym)|uniprotkb:ACC-beta(gene name synonym)|uniprotkb:Long(isoform synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-2211739(isoform-parent)|ensembl:ENSG00000076555(gene)|ensembl:ENST00000338432(transcript)|ensembl:ENST00000377848(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:P4hgekQx/AZz4InTWHW6u6jpDRA9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q6NZY4-2	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1263072|ensembl:ENSP00000438993|ensembl:ENSP00000441423	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q6nzy4-2(display_long)|uniprotkb:ZCCHC8(gene name)|psi-mi:ZCCHC8(display_short)|uniprotkb:TRAMP-like complex RNA-binding factor ZCCHC8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-1263058(zchc8_human)|ensembl:ENSG00000033030(gene)|ensembl:ENST00000536306(transcript)|ensembl:ENST00000543897(transcript)	psi-mi:"MI:0469"(intact)	-	isoform-comment:No experimental confirmation available.	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:jvdaPe814cLpLyL7r8CAd4Q0Jgg9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P62714	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q13085-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1497329|ensembl:ENSP00000478547|ensembl:ENSP00000483674	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q13085-1(display_long)|uniprotkb:ACACA(gene name)|psi-mi:ACACA(display_short)|uniprotkb:ACAC(gene name synonym)|uniprotkb:ACC1(gene name synonym)|uniprotkb:ACCA(gene name synonym)|uniprotkb:Acetyl-Coenzyme A carboxylase alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-717681(isoform-parent)|ensembl:ENSG00000275176(gene)|ensembl:ENSG00000278540(gene)|ensembl:ENST00000613687(transcript)|ensembl:ENST00000614428(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:P9d0QlkoP1zrBdF1WOrK68ueGng9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q92841-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-746027	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q92841-1(display_long)|uniprotkb:DEAD box protein p82(gene name synonym)|uniprotkb:DDX17(gene name)|psi-mi:DDX17(display_short)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:DEAD box protein p72(gene name synonym)|uniprotkb:RNA-dependent helicase p72(gene name synonym)|uniprotkb:p72(isoform synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-746012(ddx17_human)	psi-mi:"MI:0469"(intact)	-	isoform-comment:Produced by alternative initiation at Met-80 of isoform 1.	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:gbbMmoghsssWsMXlfgiV8Pg2Bf49606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P05109	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-355281|uniprotkb:Q5SY70|uniprotkb:Q9UC92|uniprotkb:Q9UCJ0|uniprotkb:A8K5L3|uniprotkb:Q9UC84|uniprotkb:Q9UCM6|uniprotkb:D3DV37|ensembl:ENSP00000357721|ensembl:ENSP00000357722	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:s10a8_human(display_long)|uniprotkb:S100A8(gene name)|psi-mi:S100A8(display_short)|uniprotkb:CAGA(gene name synonym)|uniprotkb:MRP8(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:S100 calcium-binding protein A8(gene name synonym)|uniprotkb:Calgranulin-A(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 8(gene name synonym)|uniprotkb:Cystic fibrosis antigen(gene name synonym)|uniprotkb:Leukocyte L1 complex light chain(gene name synonym)|uniprotkb:Calprotectin L1L subunit(gene name synonym)|uniprotkb:Urinary stone protein band A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001306126.1|refseq:NP_001306127.1|refseq:NP_001306130.1|refseq:NP_002955.2|go:"GO:0042060"(wound healing)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045471"(response to ethanol)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028474|go:"GO:0035662"(Toll-like receptor 4 binding)|mint:P05109|rcsb pdb:1MR8|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5HLO|rcsb pdb:5HLV|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENST00000368732(transcript)|ensembl:ENST00000368733(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002526"(acute inflammatory response)|ensembl:ENSG00000143546(gene)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002793"(positive regulation of peptide secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010043"(response to zinc ion)|go:"GO:0014002"(astrocyte development)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|dip:DIP-1165N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:3Okfhj8fxclZ0Uo/Fa1Z89qC8Ec9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q00839-2	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-351143|ensembl:ENSP00000393151	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q00839-2(display_long)|uniprotkb:HNRNPU(gene name)|psi-mi:HNRNPU(display_short)|uniprotkb:HNRPU(gene name synonym)|uniprotkb:SAFA(gene name synonym)|uniprotkb:U21.1(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:pp120(gene name synonym)|uniprotkb:C1orf199(gene name synonym)|uniprotkb:GRIP120(gene name synonym)|uniprotkb:Nuclear p120 ribonucleoprotein(gene name synonym)|uniprotkb:Scaffold-attachment factor A(gene name synonym)|uniprotkb:Short(isoform synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-351126(hnrpu_human)|ensembl:ENSG00000153187(gene)|ensembl:ENST00000444376(transcript)|uniprotkb:Q00839-2(isoform-parent)	psi-mi:"MI:0469"(intact)	-	isoform-comment:Contains a N6-acetyllysine at position 215.	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:ZldKJyn+DVBGTl23VqnG4lcmk7c9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P81605	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q14244-3	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-2211285|ensembl:ENSP00000483511	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q14244-3(display_long)|uniprotkb:MAP7(gene name)|psi-mi:MAP7(display_short)|uniprotkb:Epithelial microtubule-associated protein of 115 kDa(gene name synonym)|uniprotkb:Microtubule-associated protein 7(gene name synonym)|uniprotkb:E-MAP-115-95(isoform synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-2211064(isoform-parent)|ensembl:ENSG00000135525(gene)|ensembl:ENST00000616617(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:miqR4QlTDQOluJNI+Wc7A2QFhSE9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P08779	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356410|uniprotkb:P30654|uniprotkb:Q16402|uniprotkb:Q9UBG8|uniprotkb:A8K488|ensembl:ENSP00000301653	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:k1c16_human(display_long)|uniprotkb:KRT16(gene name)|psi-mi:KRT16(display_short)|uniprotkb:KRT16A(gene name synonym)|uniprotkb:Keratin-16(gene name synonym)|uniprotkb:Cytokeratin-16(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_005548.2|ensembl:ENSG00000186832(gene)|ensembl:ENST00000301653(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0006954"(inflammatory response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007568"(aging)|go:"GO:0030216"(keratinocyte differentiation)|reactome:R-HSA-6805567|reactome:R-HSA-6809371|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031424"(keratinization)|go:"GO:0042633"(hair cycle)|go:"GO:0045087"(innate immune response)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0051546"(keratinocyte migration)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P08779	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:NkPTLkWquNNlGYbrXaRkyRmKvmM9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P07437	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P49368	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q96BD8	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-741854|uniprotkb:B2R9Y6|uniprotkb:B4E0P4|ensembl:ENSP00000285116|ensembl:ENSP00000381470|ensembl:ENSP00000458992|ensembl:ENSP00000478259	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:ska1_human(display_long)|uniprotkb:SKA1(gene name)|psi-mi:SKA1(display_short)|uniprotkb:C18orf24(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001034624.1|refseq:NP_659497.1|ensembl:ENSG00000154839(gene)|ensembl:ENSG00000262634(gene)|ensembl:ENST00000285116(transcript)|ensembl:ENST00000398452(transcript)|ensembl:ENST00000571751(transcript)|ensembl:ENST00000616604(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|interpro:IPR009829(Protein of unknown function DUF1395)|interpro:IPR042031|mint:Q96BD8|rcsb pdb:4AJ5|rcsb pdb:4C9Y|rcsb pdb:4CA0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:Z7y57MeLsUJK0R9JNqHJNBbKr/89606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P62701	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-354303|uniprotkb:P12631|uniprotkb:P12750|uniprotkb:P27576|uniprotkb:Q14727|uniprotkb:P55831|uniprotkb:Q6IPY4|ensembl:ENSP00000362744	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rs4x_human(display_long)|uniprotkb:RPS4X(gene name)|psi-mi:RPS4X(display_short)|uniprotkb:CCG2(gene name synonym)|uniprotkb:RPS4(gene name synonym)|uniprotkb:SCAR(gene name synonym)|uniprotkb:Single copy abundant mRNA protein(gene name synonym)|uniprotkb:SCR10(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_000998.1|rcsb pdb:6OLI|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000198034(gene)|ensembl:ENST00000316084(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000876(Ribosomal protein S4e)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005824(KOW)|interpro:IPR013843(Ribosomal protein S4e, N-terminal)|interpro:IPR013845(Ribosomal protein S4e, central)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR018199|interpro:IPR032277|interpro:IPR036986|interpro:IPR038237|interpro:IPR041982|mint:P62701|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|go:"GO:0045727"(positive regulation of translation)|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:2ZuLXqBSDkK0CtN3mnIDoFAR8yI9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P30154	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P13647	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-702187|uniprotkb:Q6PI71|uniprotkb:Q6UBJ0|uniprotkb:Q8TA91|ensembl:ENSP00000252242	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:k2c5_human(display_long)|uniprotkb:Cytokeratin-5(gene name synonym)|uniprotkb:58 kDa cytokeratin(gene name synonym)|uniprotkb:KRT5(gene name)|psi-mi:KRT5(display_short)|uniprotkb:Keratin-5(gene name synonym)|uniprotkb:Type-II keratin Kb5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_000415.2|dip:DIP-39N|ensembl:ENSG00000186081(gene)|ensembl:ENST00000252242(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0045095"(keratin filament)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P13647|rcsb pdb:3TNU|rcsb pdb:6JFV|reactome:R-HSA-446107|reactome:R-HSA-6805567|reactome:R-HSA-6809371	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:BdtVgSlWFYS/+zyXLNxvrcSWc4I9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P08107	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:"GO:0005829"(cytosol)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0030529"|go:"GO:0005524"(ATP binding)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0042026"(protein refolding)|go:"GO:0006986"(response to unfolded protein)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0031982"(vesicle)|go:"GO:0010467"(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0050821"(protein stabilization)|go:"GO:0005654"(nucleoplasm)|go:"GO:1900034"(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:"GO:0016235"(aggresome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0001618"(virus receptor activity)|rcsb pdb:4J8F|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016234"(inclusion body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044822"|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0005814"(centriole)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042623"|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR029047|interpro:IPR029048|ensembl:ENST00000375650|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0031397"(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:NFv4uj12xAWIr+OltarRlLDPr949606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q96RF1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-2211196	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q96rf1_human(display_long)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	interpro:IPR044713|go:"GO:0006457"(protein folding)|go:"GO:0030544"(Hsp70 protein binding)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:m3wiJamjfqpEe3yxy+j/8W5znFs9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P68371	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P46940	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-297509|ensembl:ENSP00000268182|uniprotkb:A7MBM3	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:iqga1_human(display_long)|uniprotkb:IQGAP1(gene name)|psi-mi:IQGAP1(display_short)|uniprotkb:KIAA0051(gene name synonym)|uniprotkb:p195(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000140575(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|ensembl:ENST00000268182(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036057"(slit diaphragm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000048(IQ calmodulin-binding region)|go:"GO:0030667"(secretory granule membrane)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR027417|interpro:IPR036872|mint:P46940|rcsb pdb:1X0H|rcsb pdb:2RR8|rcsb pdb:3FAY|rcsb pdb:3I6X|rcsb pdb:5L0O|reactome:R-HSA-373753|reactome:R-HSA-381676|reactome:R-HSA-5626467|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:NP_003861.1|dip:DIP-32597N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:nXO2Z6Qn8EQGfziT8dnWz1pbK/w9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q8WVK7	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-1773994|uniprotkb:A6NIL3|uniprotkb:B3KPL3|uniprotkb:E9PCB8|ensembl:ENSP00000333433	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:ska2_human(display_long)|uniprotkb:SKA2(gene name)|psi-mi:SKA2(display_short)|uniprotkb:FAM33A(gene name synonym)|uniprotkb:Protein FAM33A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001094065.1|refseq:NP_872426.1|ensembl:ENSG00000182628(gene)|ensembl:ENST00000330137(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0051301"(cell division)|interpro:IPR026762|interpro:IPR042091|mint:Q8WVK7|rcsb pdb:4AJ5|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:OxuqjB9I67fkmxHRa5g1u6KMvAg9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q13263-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-413356|ensembl:ENSP00000253024	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:q13263-1(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-78139(tif1b_human)|ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P60660	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-300817|uniprotkb:P16475|uniprotkb:P24572|uniprotkb:P24573|uniprotkb:Q12790|ensembl:ENSP00000446955|ensembl:ENSP00000448101|uniprotkb:Q6IAZ0|uniprotkb:Q6IPY5|uniprotkb:Q561V9	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:myl6_human(display_long)|uniprotkb:MYL6(gene name)|psi-mi:MYL6(display_short)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6(gene name synonym)|uniprotkb:Myosin light chain alkali 3(gene name synonym)|uniprotkb:Myosin light chain 3(gene name synonym)|uniprotkb:17 kDa myosin light chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000092841(gene)|ensembl:ENST00000548293(transcript)|ensembl:ENST00000550697(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P60660|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:NP_066299.2|refseq:NP_524147.2	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:LhE3NUqcuHlOla13C0vjnFZfzy89606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P50990	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:Q06830	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-353193|ensembl:ENSP00000262746|ensembl:ENSP00000361152|ensembl:ENSP00000389047|ensembl:ENSP00000407034|ensembl:ENSP00000503140|uniprotkb:P35703|uniprotkb:Q2V576|uniprotkb:Q5T154|uniprotkb:Q5T155|uniprotkb:B5BU26|uniprotkb:D3DPZ8	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:prdx1_human(display_long)|uniprotkb:PRDX1(gene name)|psi-mi:PRDX1(display_short)|uniprotkb:PAGA(gene name synonym)|uniprotkb:PAGB(gene name synonym)|uniprotkb:TDPX2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Proliferation-associated gene protein(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor A(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	ensembl:ENSG00000117450(gene)|ensembl:ENST00000262746(transcript)|ensembl:ENST00000319248(transcript)|ensembl:ENST00000424390(transcript)|ensembl:ENST00000447184(transcript)|ensembl:ENST00000676549(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003723"(RNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042470"(melanosome)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q06830|rcsb pdb:2RII|rcsb pdb:3HY2|rcsb pdb:4XCS|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803|refseq:NP_001189360.1|refseq:NP_002565.1|refseq:NP_859047.1|refseq:NP_859048.1|dip:DIP-33152N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:ZM5ZXF900izH81QVqgd2+opwMrs9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P10412	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-358163|uniprotkb:Q4VB25|ensembl:ENSP00000307705	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:h14_human(display_long)|uniprotkb:H1-4(gene name)|psi-mi:H1-4(display_short)|uniprotkb:H1F4(gene name synonym)|uniprotkb:HIST1H1E(gene name synonym)|uniprotkb:Histone H1b(gene name synonym)|uniprotkb:Histone H1s-4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_005312.1|rcsb pdb:6H8P|rcsb pdb:7K5Y|rcsb pdb:7K63|go:"GO:0032564"(dATP binding)|go:"GO:0043531"(ADP binding)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P10412|rcsb pdb:3TZD|rcsb pdb:5JJZ|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000168298(gene)|ensembl:ENST00000304218(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0000792"(heterochromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016208"(AMP binding)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:yT8wBbspLLR8G3DrgpFeWEOPgac9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:O95816	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P62753	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-356625|uniprotkb:P08227|uniprotkb:P10660|uniprotkb:Q4VBY7|uniprotkb:Q8N6Z7|ensembl:ENSP00000369757	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:rs6_human(display_long)|uniprotkb:RPS6(gene name)|psi-mi:RPS6(display_short)|uniprotkb:Phosphoprotein NP33(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS6(gene name synonym)|uniprotkb:OK/SW-cl.2(orf name)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	refseq:NP_001001.2|reactome:R-HSA-166208|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR014401(Ribosomal protein S6, eukaryotic)|interpro:IPR018282|mint:P62753|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6F4P|rcsb pdb:6F4Q|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|ensembl:ENSG00000137154(gene)|ensembl:ENST00000380394(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001890"(placenta development)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022605"(mammalian oogenesis stage)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030425"(dendrite)|go:"GO:0031929"(TOR signaling)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048821"(erythrocyte development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001377(Ribosomal protein S6e)|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|dip:DIP-31507N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:beDuXCIqL99V9JlVfpzx7MdpH689606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q00005	uniprotkb:P11142-1	intact:EBI-1052159|uniprotkb:D3DQF7|uniprotkb:D3DQF8|uniprotkb:A6NEJ2|uniprotkb:A8K102|uniprotkb:B3KPD0|uniprotkb:B7Z2F2|uniprotkb:B7Z304|uniprotkb:G3V149|ensembl:ENSP00000377931|ensembl:ENSP00000377933	intact:EBI-351908|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125	psi-mi:2abb_human(display_long)|uniprotkb:PP2A subunit B isoform beta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-beta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-beta(gene name synonym)|uniprotkb:PPP2R2B(gene name)|psi-mi:PPP2R2B(display_short)|uniprotkb:PP2A subunit B isoform R2-beta(gene name synonym)	psi-mi:p11142-1(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Glatter et al.	imex:IM-9155|pubmed:19156129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2211497|imex:IM-9155-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858062.1|refseq:NP_858063.1|refseq:NP_858064.1|refseq:NP_001258828.1|refseq:NP_001258829.1|refseq:NP_001258877.1|refseq:NP_858060.2|refseq:NP_858061.2|ensembl:ENSG00000156475(gene)|ensembl:ENST00000394409(transcript)|ensembl:ENST00000394411(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322	intact:EBI-351896(hsp7c_human)|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)	psi-mi:"MI:0469"(intact)	-	-	figure legend:3B and table S2|caution:"The participant EBI-465144(P13645) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-1773949(Q9BXL8) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:NDPK - Interactions involving proteins containing InterPro domain IPR001564, Nucleoside diphosphate kinase, core.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/09	2018/04/06	rogid:qUT1TZFac7lU3GrqFO2xgN///T49606	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	intact-crc:BEB78C2B44B27839|rigid:KEWvvwwnimuWYnNg5PQkHnT4MLw	false	tandem tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)