#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9JI18 uniprotkb:Q9WVI9-1 intact:EBI-8294317|intact:MINT-1951413|uniprotkb:Q8BZM7|uniprotkb:Q8BZD3 intact:EBI-288461|ensembl:ENSMUSP00000050773|intact:EBI-8521693|intact:EBI-8521398|intact:EBI-8521723|intact:EBI-8521758|intact:MINT-126900 psi-mi:lrp1b_mouse(display_long)|uniprotkb:Lrp1b(gene name)|psi-mi:Lrp1b(display_short)|uniprotkb:Lrpdit(gene name synonym)|uniprotkb:Low-density lipoprotein receptor-related protein-deleted in tumor(gene name synonym) psi-mi:q9wvi9-1(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Prkm8ip(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shiroshima et al. (2009) mint:MINT-6801000|pubmed:19071120|imex:IM-11666|mint:d-08-02060|doi:10.1016/j.febslet.2008.11.045 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8521435|mint:MINT-6801008|imex:IM-11666-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032485|interpro:IPR018097|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR026823|interpro:IPR036055|mint:Q9JI18|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043235"(receptor complex)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|mint:MINT-6801010(identity) intact:EBI-74515(jip1_mouse)|ensembl:ENSMUSG00000027223(gene)|ensembl:ENSMUST00000050312(transcript)|mint:MINT-6801011(identity) - comment:mint|function:Potential cell surface proteins that bind and internalize ligands in the process of receptor-mediated endocytosis - figure legend:F1B F2A F2B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2008/11/26 2014/10/16 rogid:nsQ23JZaoGnGFCJ7ConZRTVHMSM10090 rogid:r8Xy/vpp0kYLCZ7vw1sE666dk/g10090 intact-crc:75B34BE02EDE4215|rigid:+n0EXkp3p6YTVJ+/fKSddibGXj8 false binding-associated region:4467-4599(MINT-6801020)|tag:?-?(MINT-6801017) binding-associated region:558-707(MINT-6801026)|tag:?-?(MINT-6801023) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q80VC8 uniprotkb:Q9JI18 intact:EBI-8521477|intact:UNK-5499853 intact:EBI-8294317|intact:MINT-1951413|uniprotkb:Q8BZM7|uniprotkb:Q8BZD3 psi-mi:q80vc8_mouse(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym) psi-mi:lrp1b_mouse(display_long)|uniprotkb:Lrp1b(gene name)|psi-mi:Lrp1b(display_short)|uniprotkb:Lrpdit(gene name synonym)|uniprotkb:Low-density lipoprotein receptor-related protein-deleted in tumor(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shiroshima et al. (2009) mint:MINT-6801000|pubmed:19071120|imex:IM-11666|mint:d-08-02060|doi:10.1016/j.febslet.2008.11.045 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8521500|mint:MINT-6801030|imex:IM-11666-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR030798|interpro:IPR010504(Arfaptin-like)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR027267|interpro:IPR037959|interpro:IPR036034|mint:Q80VC8|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015844"(monoamine transport)|go:"GO:0016301"(kinase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|mint:MINT-6801038(identity) interpro:IPR032485|interpro:IPR018097|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR026823|interpro:IPR036055|mint:Q9JI18|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043235"(receptor complex)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|mint:MINT-6801032(identity) - comment:mint comment:mint|function:Potential cell surface proteins that bind and internalize ligands in the process of receptor-mediated endocytosis figure legend:F1B F2C F2D|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2008/11/26 2014/10/16 rogid:W3AuyEc7Fk9YxNSKDAT5gYixYDc10090 rogid:nsQ23JZaoGnGFCJ7ConZRTVHMSM10090 intact-crc:15ECA743C1534B8D|rigid:yXSTQOKmpaTPWeh7AZrF+hSgBwk false mutation disrupting interaction:27-27(MINT-6801464)|tag:?-?(MINT-6801042) binding-associated region:4597-4599(MINT-6801033)|tag:?-?(MINT-6801035) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JI18 uniprotkb:Q9ERE9 intact:EBI-8294317|intact:MINT-1951413|uniprotkb:Q8BZM7|uniprotkb:Q8BZD3 intact:EBI-74576|ensembl:ENSMUSP00000023291|uniprotkb:Q9CXI4 psi-mi:lrp1b_mouse(display_long)|uniprotkb:Lrp1b(gene name)|psi-mi:Lrp1b(display_short)|uniprotkb:Lrpdit(gene name synonym)|uniprotkb:Low-density lipoprotein receptor-related protein-deleted in tumor(gene name synonym) psi-mi:jip2_mouse(display_long)|uniprotkb:Mapk8ip2(gene name)|psi-mi:Mapk8ip2(display_short)|uniprotkb:Ib2(gene name synonym)|uniprotkb:Jip2(gene name synonym)|uniprotkb:Islet-brain-2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 2(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shiroshima et al. (2009) mint:MINT-6801000|pubmed:19071120|imex:IM-11666|mint:d-08-02060|doi:10.1016/j.febslet.2008.11.045 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8521526|mint:MINT-6801052|imex:IM-11666-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032485|interpro:IPR018097|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR026823|interpro:IPR036055|mint:Q9JI18|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043235"(receptor complex)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|mint:MINT-6801062(identity) ensembl:ENSMUSG00000022619(gene)|ensembl:ENSMUST00000023291(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007254"(JNK cascade)|go:"GO:0035176"(social behavior)|go:"GO:0007617"(mating behavior)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046958"(nonassociative learning)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0014069"(postsynaptic density)|interpro:IPR001452(Src homology-3)|go:"GO:0019894"(kinesin binding)|interpro:IPR006020(Phosphotyrosine interaction region)|go:"GO:0019901"(protein kinase binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035637|mint:Q9ERE9|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|refseq:NP_068740.3|mint:MINT-6801054(identity) - comment:mint|function:Potential cell surface proteins that bind and internalize ligands in the process of receptor-mediated endocytosis - figure legend:F1B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2008/11/26 2014/10/16 rogid:nsQ23JZaoGnGFCJ7ConZRTVHMSM10090 rogid:NUVswDC52pSAuf8BL8b9wqVc8ng10090 intact-crc:DBD119439D29AA12|rigid:K1UHFWvv0QD2mrJLI68vF5A2g1o false binding-associated region:4467-4599(MINT-6801450)|tag:?-?(MINT-6801063) binding-associated region:615-830(MINT-6801453)|tag:?-?(MINT-6801055) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9JI18 uniprotkb:P69566 intact:EBI-8294317|intact:MINT-1951413|uniprotkb:Q8BZM7|uniprotkb:Q8BZD3 intact:EBI-772305|uniprotkb:P84500|uniprotkb:Q3V136 psi-mi:lrp1b_mouse(display_long)|uniprotkb:Lrp1b(gene name)|psi-mi:Lrp1b(display_short)|uniprotkb:Lrpdit(gene name synonym)|uniprotkb:Low-density lipoprotein receptor-related protein-deleted in tumor(gene name synonym) psi-mi:ranb9_mouse(display_long)|uniprotkb:Ran-binding protein M(gene name synonym)|uniprotkb:B-cell antigen receptor Ig beta-associated protein 1(gene name synonym)|uniprotkb:Ranbp9(gene name)|psi-mi:Ranbp9(display_short)|uniprotkb:Ranbpm(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shiroshima et al. (2009) mint:MINT-6801000|pubmed:19071120|imex:IM-11666|mint:d-08-02060|doi:10.1016/j.febslet.2008.11.045 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8521595|mint:MINT-6801090|imex:IM-11666-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032485|interpro:IPR018097|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR026823|interpro:IPR036055|mint:Q9JI18|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043235"(receptor complex)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|mint:MINT-6801098(identity) refseq:NP_064314.2|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR024964|mint:P69566|interpro:IPR035782|interpro:IPR043136|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1902993"(positive regulation of amyloid precursor protein catabolic process)|reactome:R-MMU-373760|reactome:R-MMU-5673001|reactome:R-MMU-8851805|mint:MINT-6801092(identity) - comment:mint|function:Potential cell surface proteins that bind and internalize ligands in the process of receptor-mediated endocytosis - figure legend:F1B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2008/11/26 2014/10/16 rogid:nsQ23JZaoGnGFCJ7ConZRTVHMSM10090 rogid:nKjsQ+KN8Z4mWEyQcRejUCLSDJY10090 intact-crc:3D2FBDFC2595283C|rigid:+8GixoOzJaQ1t+9rEzP0LB8xvEY false binding-associated region:4467-4599(MINT-6801447)|tag:?-?(MINT-6801099) tag:?-?(MINT-6801095)|binding-associated region:47-652(MINT-6801093) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q925E0 uniprotkb:Q9JI18 intact:EBI-8521556|uniprotkb:B2RSQ0|intact:UNK-5532739|ensembl:ENSMUSP00000021004 intact:EBI-8294317|intact:MINT-1951413|uniprotkb:Q8BZM7|uniprotkb:Q8BZD3 psi-mi:sntg2_mouse(display_long)|uniprotkb:Sntg2(gene name)|psi-mi:Sntg2(display_short)|uniprotkb:Syntrophin-5(gene name synonym) psi-mi:lrp1b_mouse(display_long)|uniprotkb:Lrp1b(gene name)|psi-mi:Lrp1b(display_short)|uniprotkb:Lrpdit(gene name synonym)|uniprotkb:Low-density lipoprotein receptor-related protein-deleted in tumor(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shiroshima et al. (2009) mint:MINT-6801000|pubmed:19071120|imex:IM-11666|mint:d-08-02060|doi:10.1016/j.febslet.2008.11.045 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8521551|mint:MINT-6801075|imex:IM-11666-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766539.2|ensembl:ENSMUSG00000020672(gene)|ensembl:ENSMUST00000021004(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0097109"(neuroligin family protein binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR036034|mint:Q925E0|mint:MINT-6801077(identity) interpro:IPR032485|interpro:IPR018097|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR026823|interpro:IPR036055|mint:Q9JI18|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043235"(receptor complex)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|mint:MINT-6801081(identity) - comment:mint|function:Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex comment:mint|function:Potential cell surface proteins that bind and internalize ligands in the process of receptor-mediated endocytosis figure legend:F1B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2008/11/26 2014/10/16 rogid:8A7Dm4xWGrV9Zeb8BTMq2gTwvcg10090 rogid:nsQ23JZaoGnGFCJ7ConZRTVHMSM10090 intact-crc:2360F4E5F8C08017|rigid:a/GCIkZX/WtJgSmeHLVZF3PtGX0 false tag:?-?(MINT-6801078)|binding-associated region:9-539(MINT-6801086) tag:?-?(MINT-6801082)|binding-associated region:4467-4599(MINT-6801444) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03160 uniprotkb:Q9JI18 intact:EBI-7100053|ensembl:ENSMUSP00000019456|uniprotkb:Q3TH55|intact:MINT-4544456 intact:EBI-8294317|intact:MINT-1951413|uniprotkb:Q8BZM7|uniprotkb:Q8BZD3 psi-mi:grb7_mouse(display_long)|uniprotkb:Grb7(gene name)|psi-mi:Grb7(display_short)|uniprotkb:GRB7 adapter protein(gene name synonym)|uniprotkb:Epidermal growth factor receptor GRB-7(gene name synonym) psi-mi:lrp1b_mouse(display_long)|uniprotkb:Lrp1b(gene name)|psi-mi:Lrp1b(display_short)|uniprotkb:Lrpdit(gene name synonym)|uniprotkb:Low-density lipoprotein receptor-related protein-deleted in tumor(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shiroshima et al. (2009) mint:MINT-6801000|pubmed:19071120|imex:IM-11666|mint:d-08-02060|doi:10.1016/j.febslet.2008.11.045 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8521620|mint:MINT-6801108|imex:IM-11666-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006532296.1|ensembl:ENSMUSG00000019312(gene)|ensembl:ENSMUST00000019456(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015042("BPS (Between PH and SH2)")|interpro:IPR029071|interpro:IPR035032|interpro:IPR036860|interpro:IPR039664|interpro:IPR039665|mint:Q03160|reactome:R-MMU-1433557|reactome:R-MMU-186763|reactome:R-MMU-210993|reactome:R-MMU-8853659|reactome:R-MMU-9696273|refseq:NP_034476.1|dip:DIP-43965N|mint:MINT-6801110(identity) interpro:IPR032485|interpro:IPR018097|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR026823|interpro:IPR036055|mint:Q9JI18|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043235"(receptor complex)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|mint:MINT-6801116(identity) - function:Interacts with the cytoplasmic domain of the epidermal growth factor receptor which is then inhibited. The interaction is mediated by the SH2 domain. Also binds to ERBB2|comment:mint comment:mint|function:Potential cell surface proteins that bind and internalize ligands in the process of receptor-mediated endocytosis figure legend:F1B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2008/11/26 2014/10/16 rogid:ysRuIDlVygsL9Hy9QANXt3OENSc10090 rogid:nsQ23JZaoGnGFCJ7ConZRTVHMSM10090 intact-crc:EAA232B27C19F592|rigid:Gg8eJSSY8vBQ3dJKZsdF8siwuvQ false tag:?-?(MINT-6801111)|binding-associated region:191-535(MINT-6801113) tag:?-?(MINT-6801117)|binding-associated region:4467-4599(MINT-6801441) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q80VC8 uniprotkb:Q9JI18 intact:EBI-8521477|intact:UNK-5499853 intact:EBI-8294317|intact:MINT-1951413|uniprotkb:Q8BZM7|uniprotkb:Q8BZD3 psi-mi:q80vc8_mouse(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym) psi-mi:lrp1b_mouse(display_long)|uniprotkb:Lrp1b(gene name)|psi-mi:Lrp1b(display_short)|uniprotkb:Lrpdit(gene name synonym)|uniprotkb:Low-density lipoprotein receptor-related protein-deleted in tumor(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shiroshima et al. (2009) mint:MINT-6801000|pubmed:19071120|imex:IM-11666|mint:d-08-02060|doi:10.1016/j.febslet.2008.11.045 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8521645|mint:MINT-6801468|imex:IM-11666-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR030798|interpro:IPR010504(Arfaptin-like)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR027267|interpro:IPR037959|interpro:IPR036034|mint:Q80VC8|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015844"(monoamine transport)|go:"GO:0016301"(kinase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|mint:MINT-6801470(identity) interpro:IPR032485|interpro:IPR018097|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR026823|interpro:IPR036055|mint:Q9JI18|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043235"(receptor complex)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|mint:MINT-6801476(identity) - comment:mint comment:mint|function:Potential cell surface proteins that bind and internalize ligands in the process of receptor-mediated endocytosis figure legend:F1B F2C F2D|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2008/11/26 2014/10/16 rogid:W3AuyEc7Fk9YxNSKDAT5gYixYDc10090 rogid:nsQ23JZaoGnGFCJ7ConZRTVHMSM10090 intact-crc:6DB9935F152238B3|rigid:yXSTQOKmpaTPWeh7AZrF+hSgBwk false mutation disrupting interaction:27-27(MINT-6801471)|mutation disrupting interaction:28-28(MINT-6801484)|tag:?-?(MINT-6801473) tag:?-?(MINT-6801477)|binding-associated region:4597-4599(MINT-6801479) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JI18 uniprotkb:Q9WVI9-1 intact:EBI-8294317|intact:MINT-1951413|uniprotkb:Q8BZM7|uniprotkb:Q8BZD3 intact:EBI-288461|ensembl:ENSMUSP00000050773|intact:EBI-8521693|intact:EBI-8521398|intact:EBI-8521723|intact:EBI-8521758|intact:MINT-126900 psi-mi:lrp1b_mouse(display_long)|uniprotkb:Lrp1b(gene name)|psi-mi:Lrp1b(display_short)|uniprotkb:Lrpdit(gene name synonym)|uniprotkb:Low-density lipoprotein receptor-related protein-deleted in tumor(gene name synonym) psi-mi:q9wvi9-1(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Prkm8ip(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shiroshima et al. (2009) mint:MINT-6801000|pubmed:19071120|imex:IM-11666|mint:d-08-02060|doi:10.1016/j.febslet.2008.11.045 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8521688|mint:MINT-6801131|imex:IM-11666-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032485|interpro:IPR018097|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR026823|interpro:IPR036055|mint:Q9JI18|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043235"(receptor complex)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|mint:MINT-6801141(identity) intact:EBI-74515(jip1_mouse)|ensembl:ENSMUSG00000027223(gene)|ensembl:ENSMUST00000050312(transcript)|mint:MINT-6801133(identity) - comment:mint|function:Potential cell surface proteins that bind and internalize ligands in the process of receptor-mediated endocytosis - figure legend:F3A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2008/11/26 2014/10/16 rogid:nsQ23JZaoGnGFCJ7ConZRTVHMSM10090 rogid:r8Xy/vpp0kYLCZ7vw1sE666dk/g10090 intact-crc:B2FFC0E9AB08E7E3|rigid:+n0EXkp3p6YTVJ+/fKSddibGXj8 false flag tag:?-?(MINT-6801142)|binding-associated region:3276-4599(MINT-6801493) t7 tag:?-?(MINT-6801134) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9JI18 uniprotkb:Q9WVI9-1 intact:EBI-8294317|intact:MINT-1951413|uniprotkb:Q8BZM7|uniprotkb:Q8BZD3 intact:EBI-288461|ensembl:ENSMUSP00000050773|intact:EBI-8521693|intact:EBI-8521398|intact:EBI-8521723|intact:EBI-8521758|intact:MINT-126900 psi-mi:lrp1b_mouse(display_long)|uniprotkb:Lrp1b(gene name)|psi-mi:Lrp1b(display_short)|uniprotkb:Lrpdit(gene name synonym)|uniprotkb:Low-density lipoprotein receptor-related protein-deleted in tumor(gene name synonym) psi-mi:q9wvi9-1(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Prkm8ip(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shiroshima et al. (2009) mint:MINT-6801000|pubmed:19071120|imex:IM-11666|mint:d-08-02060|doi:10.1016/j.febslet.2008.11.045 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8521737|mint:MINT-6801158|imex:IM-11666-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032485|interpro:IPR018097|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR026823|interpro:IPR036055|mint:Q9JI18|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043235"(receptor complex)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|mint:MINT-6801160(identity) intact:EBI-74515(jip1_mouse)|ensembl:ENSMUSG00000027223(gene)|ensembl:ENSMUST00000050312(transcript)|mint:MINT-6801164(identity) - comment:mint|function:Potential cell surface proteins that bind and internalize ligands in the process of receptor-mediated endocytosis - figure legend:F3A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2008/11/26 2014/10/16 rogid:nsQ23JZaoGnGFCJ7ConZRTVHMSM10090 rogid:r8Xy/vpp0kYLCZ7vw1sE666dk/g10090 intact-crc:A55BFB60C5BD721B|rigid:+n0EXkp3p6YTVJ+/fKSddibGXj8 false flag tag:?-?(MINT-6801161)|binding-associated region:3276-4599(MINT-6801496) t7 tag:?-?(MINT-6801165) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9WVI9-1 uniprotkb:Q8VI56 intact:EBI-288461|ensembl:ENSMUSP00000050773|intact:EBI-8521693|intact:EBI-8521398|intact:EBI-8521723|intact:EBI-8521758|intact:MINT-126900 intact:EBI-2106160|uniprotkb:Q8BPX5|uniprotkb:Q8CBB3|uniprotkb:Q8CCP5|uniprotkb:A2AGT4|ensembl:ENSMUSP00000028689 psi-mi:q9wvi9-1(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Prkm8ip(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym) psi-mi:lrp4_mouse(display_long)|uniprotkb:Lrp4(gene name)|psi-mi:Lrp4(display_short)|uniprotkb:Kiaa0816(gene name synonym)|uniprotkb:LDLR dan(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shiroshima et al. (2009) mint:MINT-6801000|pubmed:19071120|imex:IM-11666|mint:d-08-02060|doi:10.1016/j.febslet.2008.11.045 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8521772|mint:MINT-6801173|imex:IM-11666-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-74515(jip1_mouse)|ensembl:ENSMUSG00000027223(gene)|ensembl:ENSMUST00000050312(transcript)|mint:MINT-6801175(identity) refseq:NP_001139329.1|refseq:NP_766256.3|ensembl:ENSMUSG00000027253(gene)|ensembl:ENSMUST00000028689(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001942"(hair follicle development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030425"(dendrite)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0060173"(limb development)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0150094"(amyloid-beta clearance by cellular catabolic process)|go:"GO:1901631"(positive regulation of presynaptic membrane organization)|go:"GO:1904395"(positive regulation of skeletal muscle acetylcholine-gated channel clustering)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR023415|interpro:IPR026823|interpro:IPR036055|mint:Q8VI56|mint:MINT-6801179(identity) - - - figure legend:F3B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2008/11/26 2014/10/16 rogid:r8Xy/vpp0kYLCZ7vw1sE666dk/g10090 rogid:ZKhXi4AMVjK5LFe+xQHieJ2bomY10090 intact-crc:D5A260AA69F761AB|rigid:K81y1NkNAd1+X3oL4t0KBzQPku4 false t7 tag:?-?(MINT-6801176) ha tag:?-?(MINT-6801180) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P69566 uniprotkb:Q8VI56 intact:EBI-772305|uniprotkb:P84500|uniprotkb:Q3V136 intact:EBI-2106160|uniprotkb:Q8BPX5|uniprotkb:Q8CBB3|uniprotkb:Q8CCP5|uniprotkb:A2AGT4|ensembl:ENSMUSP00000028689 psi-mi:ranb9_mouse(display_long)|uniprotkb:Ran-binding protein M(gene name synonym)|uniprotkb:B-cell antigen receptor Ig beta-associated protein 1(gene name synonym)|uniprotkb:Ranbp9(gene name)|psi-mi:Ranbp9(display_short)|uniprotkb:Ranbpm(gene name synonym) psi-mi:lrp4_mouse(display_long)|uniprotkb:Lrp4(gene name)|psi-mi:Lrp4(display_short)|uniprotkb:Kiaa0816(gene name synonym)|uniprotkb:LDLR dan(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shiroshima et al. (2009) mint:MINT-6801000|pubmed:19071120|imex:IM-11666|mint:d-08-02060|doi:10.1016/j.febslet.2008.11.045 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8521844|mint:MINT-6801244|imex:IM-11666-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064314.2|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR024964|mint:P69566|interpro:IPR035782|interpro:IPR043136|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1902993"(positive regulation of amyloid precursor protein catabolic process)|reactome:R-MMU-373760|reactome:R-MMU-5673001|reactome:R-MMU-8851805|mint:MINT-6801246(identity) refseq:NP_001139329.1|refseq:NP_766256.3|ensembl:ENSMUSG00000027253(gene)|ensembl:ENSMUST00000028689(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001942"(hair follicle development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030425"(dendrite)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0060173"(limb development)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0150094"(amyloid-beta clearance by cellular catabolic process)|go:"GO:1901631"(positive regulation of presynaptic membrane organization)|go:"GO:1904395"(positive regulation of skeletal muscle acetylcholine-gated channel clustering)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR023415|interpro:IPR026823|interpro:IPR036055|mint:Q8VI56|mint:MINT-6801250(identity) - - - figure legend:F3F|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2008/11/26 2014/10/16 rogid:nKjsQ+KN8Z4mWEyQcRejUCLSDJY10090 rogid:ZKhXi4AMVjK5LFe+xQHieJ2bomY10090 intact-crc:F2FEF91D230B3838|rigid:kYL/NJN8/piWKqXuQFSUW12IjK0 false flag tag:?-?(MINT-6801247) ha tag:?-?(MINT-6801251) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q80VC8 uniprotkb:Q8VI56 intact:EBI-8521477|intact:UNK-5499853 intact:EBI-2106160|uniprotkb:Q8BPX5|uniprotkb:Q8CBB3|uniprotkb:Q8CCP5|uniprotkb:A2AGT4|ensembl:ENSMUSP00000028689 psi-mi:q80vc8_mouse(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym) psi-mi:lrp4_mouse(display_long)|uniprotkb:Lrp4(gene name)|psi-mi:Lrp4(display_short)|uniprotkb:Kiaa0816(gene name synonym)|uniprotkb:LDLR dan(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shiroshima et al. (2009) mint:MINT-6801000|pubmed:19071120|imex:IM-11666|mint:d-08-02060|doi:10.1016/j.febslet.2008.11.045 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8521790|mint:MINT-6801231|imex:IM-11666-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR030798|interpro:IPR010504(Arfaptin-like)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR027267|interpro:IPR037959|interpro:IPR036034|mint:Q80VC8|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015844"(monoamine transport)|go:"GO:0016301"(kinase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|mint:MINT-6801237(identity) refseq:NP_001139329.1|refseq:NP_766256.3|ensembl:ENSMUSG00000027253(gene)|ensembl:ENSMUST00000028689(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001942"(hair follicle development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030425"(dendrite)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0060173"(limb development)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0150094"(amyloid-beta clearance by cellular catabolic process)|go:"GO:1901631"(positive regulation of presynaptic membrane organization)|go:"GO:1904395"(positive regulation of skeletal muscle acetylcholine-gated channel clustering)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR023415|interpro:IPR026823|interpro:IPR036055|mint:Q8VI56|mint:MINT-6801233(identity) - comment:mint - figure legend:F3D|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2008/11/26 2014/10/16 rogid:W3AuyEc7Fk9YxNSKDAT5gYixYDc10090 rogid:ZKhXi4AMVjK5LFe+xQHieJ2bomY10090 intact-crc:37DA170D41AA8869|rigid:858CxdpfBwMAl3huWWzek7nbdwY false myc tag:?-?(MINT-6801238) ha tag:?-?(MINT-6801234) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q80VC8 uniprotkb:Q9JI18 intact:EBI-8521477|intact:UNK-5499853 intact:EBI-8294317|intact:MINT-1951413|uniprotkb:Q8BZM7|uniprotkb:Q8BZD3 psi-mi:q80vc8_mouse(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym) psi-mi:lrp1b_mouse(display_long)|uniprotkb:Lrp1b(gene name)|psi-mi:Lrp1b(display_short)|uniprotkb:Lrpdit(gene name synonym)|uniprotkb:Low-density lipoprotein receptor-related protein-deleted in tumor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shiroshima et al. (2009) mint:MINT-6801000|pubmed:19071120|imex:IM-11666|mint:d-08-02060|doi:10.1016/j.febslet.2008.11.045 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8521862|mint:MINT-6801258|imex:IM-11666-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR030798|interpro:IPR010504(Arfaptin-like)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR027267|interpro:IPR037959|interpro:IPR036034|mint:Q80VC8|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015844"(monoamine transport)|go:"GO:0016301"(kinase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|mint:MINT-6801264(identity) interpro:IPR032485|interpro:IPR018097|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR026823|interpro:IPR036055|mint:Q9JI18|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043235"(receptor complex)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|mint:MINT-6801260(identity) - comment:mint comment:mint|function:Potential cell surface proteins that bind and internalize ligands in the process of receptor-mediated endocytosis figure legend:F3C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2008/11/26 2014/10/16 rogid:W3AuyEc7Fk9YxNSKDAT5gYixYDc10090 rogid:nsQ23JZaoGnGFCJ7ConZRTVHMSM10090 intact-crc:6A92D645DD3C8552|rigid:yXSTQOKmpaTPWeh7AZrF+hSgBwk false myc tag:?-?(MINT-6801265) flag tag:?-?(MINT-6801261)|binding-associated region:3276-4599(MINT-6801499) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9JI18 uniprotkb:Q80VC8 intact:EBI-8294317|intact:MINT-1951413|uniprotkb:Q8BZM7|uniprotkb:Q8BZD3 intact:EBI-8521477|intact:UNK-5499853 psi-mi:lrp1b_mouse(display_long)|uniprotkb:Lrp1b(gene name)|psi-mi:Lrp1b(display_short)|uniprotkb:Lrpdit(gene name synonym)|uniprotkb:Low-density lipoprotein receptor-related protein-deleted in tumor(gene name synonym) psi-mi:q80vc8_mouse(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shiroshima et al. (2009) mint:MINT-6801000|pubmed:19071120|imex:IM-11666|mint:d-08-02060|doi:10.1016/j.febslet.2008.11.045 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8521898|mint:MINT-6801271|imex:IM-11666-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032485|interpro:IPR018097|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR026823|interpro:IPR036055|mint:Q9JI18|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043235"(receptor complex)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|mint:MINT-6801277(identity) interpro:IPR030798|interpro:IPR010504(Arfaptin-like)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR027267|interpro:IPR037959|interpro:IPR036034|mint:Q80VC8|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015844"(monoamine transport)|go:"GO:0016301"(kinase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|mint:MINT-6801273(identity) - comment:mint|function:Potential cell surface proteins that bind and internalize ligands in the process of receptor-mediated endocytosis comment:mint figure legend:F3C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2008/11/26 2014/10/16 rogid:nsQ23JZaoGnGFCJ7ConZRTVHMSM10090 rogid:W3AuyEc7Fk9YxNSKDAT5gYixYDc10090 intact-crc:F3D2A18558D94754|rigid:yXSTQOKmpaTPWeh7AZrF+hSgBwk false flag tag:?-?(MINT-6801278)|binding-associated region:3276-4599(MINT-6801502) myc tag:?-?(MINT-6801274) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9JI18 uniprotkb:P69566 intact:EBI-8294317|intact:MINT-1951413|uniprotkb:Q8BZM7|uniprotkb:Q8BZD3 intact:EBI-772305|uniprotkb:P84500|uniprotkb:Q3V136 psi-mi:lrp1b_mouse(display_long)|uniprotkb:Lrp1b(gene name)|psi-mi:Lrp1b(display_short)|uniprotkb:Lrpdit(gene name synonym)|uniprotkb:Low-density lipoprotein receptor-related protein-deleted in tumor(gene name synonym) psi-mi:ranb9_mouse(display_long)|uniprotkb:Ran-binding protein M(gene name synonym)|uniprotkb:B-cell antigen receptor Ig beta-associated protein 1(gene name synonym)|uniprotkb:Ranbp9(gene name)|psi-mi:Ranbp9(display_short)|uniprotkb:Ranbpm(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shiroshima et al. (2009) mint:MINT-6801000|pubmed:19071120|imex:IM-11666|mint:d-08-02060|doi:10.1016/j.febslet.2008.11.045 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8521965|mint:MINT-6801284|imex:IM-11666-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032485|interpro:IPR018097|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR026823|interpro:IPR036055|mint:Q9JI18|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043235"(receptor complex)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|mint:MINT-6801290(identity) refseq:NP_064314.2|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR024964|mint:P69566|interpro:IPR035782|interpro:IPR043136|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1902993"(positive regulation of amyloid precursor protein catabolic process)|reactome:R-MMU-373760|reactome:R-MMU-5673001|reactome:R-MMU-8851805|mint:MINT-6801286(identity) - comment:mint|function:Potential cell surface proteins that bind and internalize ligands in the process of receptor-mediated endocytosis - figure legend:F3E|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2008/11/26 2014/10/16 rogid:nsQ23JZaoGnGFCJ7ConZRTVHMSM10090 rogid:nKjsQ+KN8Z4mWEyQcRejUCLSDJY10090 intact-crc:F3E49BADB0929538|rigid:+8GixoOzJaQ1t+9rEzP0LB8xvEY false flag tag:?-?(MINT-6801291)|binding-associated region:3276-4599(MINT-6801505) t7 tag:?-?(MINT-6801287) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)