#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q07471	uniprotkb:P38141	intact:EBI-19209|uniprotkb:P89098|uniprotkb:D6VRR9|ensemblfungi:YDL080C	intact:EBI-19204|uniprotkb:D6VQN6|ensemblfungi:YBR240C	psi-mi:thi3_yeast(display_long)|uniprotkb:THI3(gene name)|psi-mi:THI3(display_short)|uniprotkb:KID1(gene name synonym)|uniprotkb:Keto isocaproate decarboxylase 1(gene name synonym)|uniprotkb:Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase(gene name synonym)|uniprotkb:YDL080C(locus name)	psi-mi:thi2_yeast(display_long)|uniprotkb:THI2(gene name)|psi-mi:THI2(display_short)|uniprotkb:PHO6(gene name synonym)|uniprotkb:YBR240C(locus name)|uniprotkb:YBR1624(orf name)	psi-mi:"MI:0018"(two hybrid)	Nosaka et al. (2008)	pubmed:19013460|imex:IM-9579|mint:MINT-6797311|doi:10.1016/j.febslet.2008.10.051|mint:d-08-01720	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8496915|mint:MINT-6797316|imex:IM-9579-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010203.1|sgd:S000002238|ensemblfungi:YDL080C(gene)|ensemblfungi:YDL080C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000955"(amino acid catabolic process via Ehrlich pathway)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0016829"(lyase activity)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090180"(positive regulation of thiamine biosynthetic process)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR012110(Pyruvate decarboxylase/indolepyruvate decarboxylase)|interpro:IPR029035|interpro:IPR029061|dip:DIP-6304N|mint:Q07471|mint:MINT-6797318(identity)	sgd:S000000444|ensemblfungi:YBR240C(gene)|ensemblfungi:YBR240C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090180"(positive regulation of thiamine biosynthetic process)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR036864|refseq:NP_009799.3|dip:DIP-5362N|mint:P38141|mint:MINT-6797319(identity)	-	crc64:8EC37CC5B2BFA1AD	-	figure legend:F2|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2008/11/06	2014/10/16	rogid:+ujdngiXVPmZVgQBxwEVbCpiD94559292	rogid:Lr9JZxgJw9Qf8c6IpSGwqX5bLdk559292	intact-crc:887353E3B0AC6742|rigid:iATbTXbjPUQLtB3pi4aGnO2K2ek	false	tag:?-?(MINT-6797322)	tag:?-?(MINT-6797326)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32896	uniprotkb:Q07471	intact:EBI-13004|uniprotkb:E9PAG9|uniprotkb:D6VS68|ensemblfungi:YDR081C	intact:EBI-19209|uniprotkb:P89098|uniprotkb:D6VRR9|ensemblfungi:YDL080C	psi-mi:pdc2_yeast(display_long)|uniprotkb:PDC2(gene name)|psi-mi:PDC2(display_short)|uniprotkb:D4451(orf name)|uniprotkb:YDR081C(locus name)	psi-mi:thi3_yeast(display_long)|uniprotkb:THI3(gene name)|psi-mi:THI3(display_short)|uniprotkb:KID1(gene name synonym)|uniprotkb:Keto isocaproate decarboxylase 1(gene name synonym)|uniprotkb:Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase(gene name synonym)|uniprotkb:YDL080C(locus name)	psi-mi:"MI:0018"(two hybrid)	Nosaka et al. (2008)	pubmed:19013460|imex:IM-9579|mint:MINT-6797311|doi:10.1016/j.febslet.2008.10.051|mint:d-08-01720	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8497002|mint:MINT-6797355|imex:IM-9579-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010366.1|sgd:S000002488|interpro:IPR004875(CENP-B protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|mint:P32896|ensemblfungi:YDR081C(gene)|ensemblfungi:YDR081C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090180"(positive regulation of thiamine biosynthetic process)|go:"GO:2001172"(positive regulation of glycolytic fermentation to ethanol)|mint:MINT-6797363(identity)	refseq:NP_010203.1|sgd:S000002238|ensemblfungi:YDL080C(gene)|ensemblfungi:YDL080C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000955"(amino acid catabolic process via Ehrlich pathway)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0016829"(lyase activity)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090180"(positive regulation of thiamine biosynthetic process)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR012110(Pyruvate decarboxylase/indolepyruvate decarboxylase)|interpro:IPR029035|interpro:IPR029061|dip:DIP-6304N|mint:Q07471|mint:MINT-6797357(identity)	-	-	crc64:8EC37CC5B2BFA1AD	figure legend:F4|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2008/11/06	2014/10/16	rogid:2bviInCPtKySTr14UE856L8W+Xs559292	rogid:+ujdngiXVPmZVgQBxwEVbCpiD94559292	intact-crc:67F806CF33B38980|rigid:vbxxt4FkGvbVskAOmVrMkKf6uok	false	binding-associated region:737-889(MINT-6797369)|tag:?-?(MINT-6797364)	tag:?-?(MINT-6797360)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07471	uniprotkb:P32896	intact:EBI-19209|uniprotkb:P89098|uniprotkb:D6VRR9|ensemblfungi:YDL080C	intact:EBI-13004|uniprotkb:E9PAG9|uniprotkb:D6VS68|ensemblfungi:YDR081C	psi-mi:thi3_yeast(display_long)|uniprotkb:THI3(gene name)|psi-mi:THI3(display_short)|uniprotkb:KID1(gene name synonym)|uniprotkb:Keto isocaproate decarboxylase 1(gene name synonym)|uniprotkb:Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase(gene name synonym)|uniprotkb:YDL080C(locus name)	psi-mi:pdc2_yeast(display_long)|uniprotkb:PDC2(gene name)|psi-mi:PDC2(display_short)|uniprotkb:D4451(orf name)|uniprotkb:YDR081C(locus name)	psi-mi:"MI:0018"(two hybrid)	Nosaka et al. (2008)	pubmed:19013460|imex:IM-9579|mint:MINT-6797311|doi:10.1016/j.febslet.2008.10.051|mint:d-08-01720	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8496958|mint:MINT-6797334|imex:IM-9579-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010203.1|sgd:S000002238|ensemblfungi:YDL080C(gene)|ensemblfungi:YDL080C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000955"(amino acid catabolic process via Ehrlich pathway)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0016829"(lyase activity)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090180"(positive regulation of thiamine biosynthetic process)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR012110(Pyruvate decarboxylase/indolepyruvate decarboxylase)|interpro:IPR029035|interpro:IPR029061|dip:DIP-6304N|mint:Q07471|mint:MINT-6797344(identity)	refseq:NP_010366.1|sgd:S000002488|interpro:IPR004875(CENP-B protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|mint:P32896|ensemblfungi:YDR081C(gene)|ensemblfungi:YDR081C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090180"(positive regulation of thiamine biosynthetic process)|go:"GO:2001172"(positive regulation of glycolytic fermentation to ethanol)|mint:MINT-6797336(identity)	-	crc64:8EC37CC5B2BFA1AD	-	figure legend:F2|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2008/11/06	2014/10/16	rogid:+ujdngiXVPmZVgQBxwEVbCpiD94559292	rogid:2bviInCPtKySTr14UE856L8W+Xs559292	intact-crc:31A0E11DD1C68329|rigid:vbxxt4FkGvbVskAOmVrMkKf6uok	false	tag:?-?(MINT-6797345)|mutation increasing interaction:488-488(MINT-6797350)	tag:?-?(MINT-6797337)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07471	uniprotkb:P32896	intact:EBI-19209|uniprotkb:P89098|uniprotkb:D6VRR9|ensemblfungi:YDL080C	intact:EBI-13004|uniprotkb:E9PAG9|uniprotkb:D6VS68|ensemblfungi:YDR081C	psi-mi:thi3_yeast(display_long)|uniprotkb:THI3(gene name)|psi-mi:THI3(display_short)|uniprotkb:KID1(gene name synonym)|uniprotkb:Keto isocaproate decarboxylase 1(gene name synonym)|uniprotkb:Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase(gene name synonym)|uniprotkb:YDL080C(locus name)	psi-mi:pdc2_yeast(display_long)|uniprotkb:PDC2(gene name)|psi-mi:PDC2(display_short)|uniprotkb:D4451(orf name)|uniprotkb:YDR081C(locus name)	psi-mi:"MI:0096"(pull down)	Nosaka et al. (2008)	pubmed:19013460|imex:IM-9579|mint:MINT-6797311|doi:10.1016/j.febslet.2008.10.051|mint:d-08-01720	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8497055|mint:MINT-6797373|imex:IM-9579-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010203.1|sgd:S000002238|ensemblfungi:YDL080C(gene)|ensemblfungi:YDL080C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000955"(amino acid catabolic process via Ehrlich pathway)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0016829"(lyase activity)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090180"(positive regulation of thiamine biosynthetic process)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR012110(Pyruvate decarboxylase/indolepyruvate decarboxylase)|interpro:IPR029035|interpro:IPR029061|dip:DIP-6304N|mint:Q07471|mint:MINT-6797381(identity)	refseq:NP_010366.1|sgd:S000002488|interpro:IPR004875(CENP-B protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|mint:P32896|ensemblfungi:YDR081C(gene)|ensemblfungi:YDR081C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090180"(positive regulation of thiamine biosynthetic process)|go:"GO:2001172"(positive regulation of glycolytic fermentation to ethanol)|mint:MINT-6797375(identity)	-	crc64:8EC37CC5B2BFA1AD	-	figure legend:F3|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/06	2014/10/16	rogid:+ujdngiXVPmZVgQBxwEVbCpiD94559292	rogid:2bviInCPtKySTr14UE856L8W+Xs559292	intact-crc:9751ADDEAFB8CF0E|rigid:vbxxt4FkGvbVskAOmVrMkKf6uok	false	mutation increasing interaction:488-488(MINT-6797391)|his tag:?-?(MINT-6797382)	binding-associated region:407-925(MINT-6797376)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)