#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q99714 uniprotkb:Q7L0Y3 intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9 intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356 psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym) psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2107061|imex:IM-12139-3 author score:High - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1 refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766 go:"GO:0005739"(mitochondrion) - - figure legend:Figs. 2B|variable_condition:High|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/11/12 2014/10/16 rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606 rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606 intact-crc:9B07DF594C9E1784|rigid:wAVYN0xoUjcmdZPdfMOOg4yei1s false - his tag:c-c - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q7L0Y3 uniprotkb:P49448 intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356 intact:EBI-720168|uniprotkb:Q9UDQ4|uniprotkb:B2R8G0|ensembl:ENSP00000327589|ensembl:ENSP00000500546 psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym) psi-mi:dhe4_human(display_long)|uniprotkb:GLUD2(gene name)|psi-mi:GLUD2(display_short)|uniprotkb:GLUDP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2107075|imex:IM-12139-2 author score:Low psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766 refseq:NP_036216.2|ensembl:ENSG00000182890(gene)|ensembl:ENSG00000288118(gene)|ensembl:ENST00000328078(transcript)|ensembl:ENST00000673493(transcript)|go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0004353"("glutamate dehydrogenase [NAD(P)+] activity")|go:"GO:0004354"("glutamate dehydrogenase (NADP+) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0043531"(ADP binding)|go:"GO:0070728"(leucine binding)|interpro:IPR006095(Glutamate/phenylalanine/leucine/valine dehydrogenase)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR006097(Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region)|interpro:IPR033524|interpro:IPR033922|interpro:IPR036291|rcsb pdb:6G2U|reactome:R-HSA-2151201|reactome:R-HSA-8964539 go:"GO:0005739"(mitochondrion) - - figure legend:Figs. 3B, 3C, Supp. Table 10|variable_condition:Low|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/11/12 2014/10/16 rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606 rogid:F6sq5B69eoiIC2y3eOtEy029WQQ9606 intact-crc:FAFA60AAE2300E2C|rigid:1Y+z12jpGPr+glnid3lWFNZAizg false his tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q7L0Y3 uniprotkb:Q5T160 intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356 intact:EBI-1050546|uniprotkb:Q96FU5|uniprotkb:Q9H8K8|uniprotkb:B2RDT7|ensembl:ENSP00000358549 psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym) psi-mi:syrm_human(display_long)|uniprotkb:RARS2(gene name)|psi-mi:RARS2(display_short)|uniprotkb:RARSL(gene name synonym)|uniprotkb:Arginyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2107075|imex:IM-12139-2 author score:Low psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766 refseq:NP_064716.2|ensembl:ENSG00000146282(gene)|ensembl:ENST00000369536(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004814"(arginine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006420"(arginyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001278(Arginyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR008909(DALR anticodon binding)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR035684|interpro:IPR036695|mint:Q5T160|reactome:R-HSA-379726 go:"GO:0005739"(mitochondrion) - - figure legend:Figs. 3B, 3C, Supp. Table 10|variable_condition:Low|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/11/12 2014/10/16 rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606 rogid:jslLCkjYCriiVlR94nHAhNIYVeY9606 intact-crc:FAFA60AAE2300E2C|rigid:1Y+z12jpGPr+glnid3lWFNZAizg false his tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q7L0Y3 uniprotkb:Q9H857 intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356 intact:EBI-359244|uniprotkb:O95888|uniprotkb:Q96C80|uniprotkb:Q9H9Z8|uniprotkb:C9JTZ6|uniprotkb:E9PAL9|intact:EBI-11044897|ensembl:ENSP00000302468 psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym) psi-mi:nt5d2_human(display_long)|uniprotkb:NT5DC2(gene name)|psi-mi:NT5DC2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2107075|imex:IM-12139-2 author score:Low psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766 refseq:NP_001127703.1|refseq:NP_075059.1|refseq:XP_005265463.1|refseq:XP_006713368.1|ensembl:ENSG00000168268(gene)|ensembl:ENST00000307076(transcript)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR008380(HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase)|interpro:IPR016695(Purine 5'-nucleotidase)|interpro:IPR023214|interpro:IPR036412 go:"GO:0005739"(mitochondrion) - - figure legend:Figs. 3B, 3C, Supp. Table 10|variable_condition:Low|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/11/12 2014/10/16 rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606 rogid:nfT/9N1bWVadX70eY1G0GS9pS9U9606 intact-crc:FAFA60AAE2300E2C|rigid:1Y+z12jpGPr+glnid3lWFNZAizg false his tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q7L0Y3 uniprotkb:Q9Y3I0 intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356 intact:EBI-2107208|uniprotkb:Q6IAI0|uniprotkb:Q9BWL4|uniprotkb:Q9NTH1|uniprotkb:Q9P037|uniprotkb:Q9P0J3|uniprotkb:B2R6A8|intact:EBI-4399544|ensembl:ENSP00000216038 psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym) psi-mi:rtcb_human(display_long)|uniprotkb:3'-phosphate/5'-hydroxy nucleic acid ligase(gene name synonym)|uniprotkb:C22orf28(gene name synonym)|uniprotkb:HSPC117(orf name)|uniprotkb:RTCB(gene name)|psi-mi:RTCB(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2107075|imex:IM-12139-2 author score:Low psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766 refseq:NP_055121.1|dip:DIP-46750N|ensembl:ENSG00000100220(gene)|ensembl:ENST00000216038(transcript)|go:"GO:0000971"(tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate)|go:"GO:0003723"(RNA binding)|go:"GO:0003972"("RNA ligase (ATP) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0017166"(vinculin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0072669"(tRNA-splicing ligase complex)|interpro:IPR001233(Protein of unknown function UPF0027)|interpro:IPR027513|interpro:IPR036025|mint:Q9Y3I0|reactome:R-HSA-6784531 go:"GO:0005739"(mitochondrion) - - figure legend:Figs. 3B, 3C, Supp. Table 10|variable_condition:Low|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/11/12 2014/10/16 rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606 rogid:URuCEq/DIn6DgR3jOb5fwnpDVXE9606 intact-crc:FAFA60AAE2300E2C|rigid:1Y+z12jpGPr+glnid3lWFNZAizg false his tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q7L0Y3 uniprotkb:Q9H078 intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356 intact:EBI-2107221|uniprotkb:Q8ND11|uniprotkb:Q9H8Y0|uniprotkb:B4DXW4|uniprotkb:B4DXJ7|uniprotkb:B4DXP7|uniprotkb:E7EWN6|uniprotkb:F8W7P6|ensembl:ENSP00000294053 psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym) psi-mi:clpb_human(display_long)|uniprotkb:CLPB(gene name)|psi-mi:CLPB(display_short)|uniprotkb:HSP78(gene name synonym)|uniprotkb:SKD3(gene name synonym)|uniprotkb:Suppressor of potassium transport defect 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2107075|imex:IM-12139-2 author score:Low psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766 refseq:NP_110440.1|refseq:NP_001245321.1|refseq:NP_001245322.1|refseq:NP_001245323.1|ensembl:ENSG00000162129(gene)|ensembl:ENST00000294053(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0034605"(cellular response to heat)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR002110(Ankyrin)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR019489|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|mint:Q9H078 go:"GO:0005739"(mitochondrion) - - figure legend:Figs. 3B, 3C, Supp. Table 10|variable_condition:Low|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/11/12 2014/10/16 rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606 rogid:QqIOYOITwDC+c8kKtMGBHa/0Tjk9606 intact-crc:FAFA60AAE2300E2C|rigid:1Y+z12jpGPr+glnid3lWFNZAizg false his tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q7L0Y3 uniprotkb:P17844 intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356 intact:EBI-351962|uniprotkb:O75681|uniprotkb:Q53Y61|uniprotkb:B4DLW8|uniprotkb:E7ETL9|uniprotkb:B5BU21|uniprotkb:D3DU32|ensembl:ENSP00000225792|ensembl:ENSP00000403085|ensembl:ENSP00000463168|ensembl:ENSP00000464337|ensembl:ENSP00000504794 psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym) psi-mi:ddx5_human(display_long)|uniprotkb:HLR1(gene name synonym)|uniprotkb:DDX5(gene name)|psi-mi:DDX5(display_short)|uniprotkb:HELR(gene name synonym)|uniprotkb:G17P1(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2107075|imex:IM-12139-2 author score:Low psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766 refseq:NP_004387.1|refseq:NP_001307524.1|refseq:NP_001307525.1|dip:DIP-29844N|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P17844|rcsb pdb:3FE2|rcsb pdb:4A4D|reactome:R-HSA-3899300|reactome:R-HSA-72163|reactome:R-HSA-9018519|reactome:R-HSA-9682706|reactome:R-HSA-9694686|ensembl:ENST00000225792(transcript)|ensembl:ENST00000450599(transcript)|ensembl:ENST00000577922(transcript)|ensembl:ENST00000585111(transcript)|ensembl:ENST00000676785(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|ensembl:ENSG00000108654(gene) go:"GO:0005739"(mitochondrion) - - figure legend:Figs. 3B, 3C, Supp. Table 10|variable_condition:Low|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/11/12 2014/10/16 rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606 rogid:BlaILQg90jqkI5+DdA0k5YTCGOo9606 intact-crc:FAFA60AAE2300E2C|rigid:1Y+z12jpGPr+glnid3lWFNZAizg false his tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q7L0Y3 uniprotkb:Q9NP81 intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356 intact:EBI-1049768|uniprotkb:A6NHW7|uniprotkb:Q9BVP3|uniprotkb:B4DE10|ensembl:ENSP00000221431|ensembl:ENSP00000489539 psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym) psi-mi:sysm_human(display_long)|uniprotkb:"Seryl-tRNA(Ser/Sec) synthetase"(gene name synonym)|uniprotkb:SerRSmt(gene name synonym)|uniprotkb:SARS2(gene name)|psi-mi:SARS2(display_short)|uniprotkb:SARSM(gene name synonym)|uniprotkb:Seryl-tRNA synthetase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2107075|imex:IM-12139-2 author score:Low psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766 refseq:NP_001139373.1|refseq:NP_060297.1|interpro:IPR002317(Seryl-tRNA synthetase, class IIa)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR010978(tRNA-binding arm)|interpro:IPR033729|interpro:IPR042103|mint:Q9NP81|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|reactome:R-HSA-379726|ensembl:ENSG00000104835(gene)|ensembl:ENSG00000283104(gene)|ensembl:ENST00000221431(transcript)|ensembl:ENST00000634687(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004828"(serine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006434"(seryl-tRNA aminoacylation)|go:"GO:0070158"(mitochondrial seryl-tRNA aminoacylation)|go:"GO:0097056"("selenocysteinyl-tRNA(Sec) biosynthetic process") go:"GO:0005739"(mitochondrion) - - figure legend:Figs. 3B, 3C, Supp. Table 10|variable_condition:Low|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/11/12 2014/10/16 rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606 rogid:xYa2ZQIifKicNHV/6vlcUGaN9q49606 intact-crc:FAFA60AAE2300E2C|rigid:1Y+z12jpGPr+glnid3lWFNZAizg false his tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q7L0Y3 uniprotkb:Q99959 intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356 intact:EBI-702235|intact:EBI-2692870|uniprotkb:D3DUW9|uniprotkb:Q99960|uniprotkb:Q4VC01|uniprotkb:B8QFA1|uniprotkb:B8QGS6|uniprotkb:B8QGS7|uniprotkb:A0AV37|ensembl:ENSP00000070846 psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym) psi-mi:pkp2_human(display_long)|uniprotkb:PKP2(gene name)|psi-mi:PKP2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2107075|imex:IM-12139-2 author score:Low psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766 refseq:NP_004563.2|refseq:NP_001005242.2|ensembl:ENSG00000057294(gene)|ensembl:ENST00000070846(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002159"(desmosome assembly)|go:"GO:0002934"(desmosome organization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007507"(heart development)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0030054"(cell junction)|go:"GO:0030057"(desmosome)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|mint:Q99959|rcsb pdb:3TT9|reactome:R-HSA-6805567|reactome:R-HSA-6809371 go:"GO:0005739"(mitochondrion) - - figure legend:Figs. 3B, 3C, Supp. Table 10|variable_condition:Low|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/11/12 2014/10/16 rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606 rogid:kwGWMlk4SDz0xARlBMD1dY9fehQ9606 intact-crc:FAFA60AAE2300E2C|rigid:1Y+z12jpGPr+glnid3lWFNZAizg false his tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q7L0Y3 uniprotkb:P68104 intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2107075|imex:IM-12139-2 author score:Low psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766 refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 go:"GO:0005739"(mitochondrion) - - figure legend:Figs. 3B, 3C, Supp. Table 10|variable_condition:Low|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/11/12 2014/10/16 rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 intact-crc:FAFA60AAE2300E2C|rigid:1Y+z12jpGPr+glnid3lWFNZAizg false his tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q7L0Y3 uniprotkb:Q9HA77 intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356 intact:EBI-2107262|uniprotkb:Q8NI84|uniprotkb:Q96IV4|ensembl:ENSP00000257347 psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym) psi-mi:sycm_human(display_long)|uniprotkb:CARS2(gene name)|psi-mi:CARS2(display_short)|uniprotkb:Cysteinyl-tRNA synthetase(gene name synonym)|uniprotkb:OK/SW-cl.10(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2107075|imex:IM-12139-2 author score:Low psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766 refseq:NP_078813.1|ensembl:ENSG00000134905(gene)|ensembl:ENST00000257347(transcript)|go:"GO:0004817"(cysteine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006423"(cysteinyl-tRNA aminoacylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR015803(Cysteinyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR024909|interpro:IPR032678|reactome:R-HSA-379726 go:"GO:0005739"(mitochondrion) - - figure legend:Figs. 3B, 3C, Supp. Table 10|variable_condition:Low|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/11/12 2014/10/16 rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606 rogid:1YjqTFtsp39awdgDtBTL3AgJrp49606 intact-crc:FAFA60AAE2300E2C|rigid:1Y+z12jpGPr+glnid3lWFNZAizg false his tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q7L0Y3 uniprotkb:Q02252 intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356 intact:EBI-2107242|uniprotkb:Q9UKM8|uniprotkb:B2R609|uniprotkb:B4DFS8|uniprotkb:J3KNU8|ensembl:ENSP00000450436 psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym) psi-mi:mmsa_human(display_long)|uniprotkb:MMSDH(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 6 member A1(gene name synonym)|uniprotkb:ALDH6A1(gene name)|psi-mi:ALDH6A1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2107075|imex:IM-12139-2 author score:Low psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766 refseq:NP_005580.1|refseq:NP_001265522.1|ensembl:ENSG00000119711(gene)|ensembl:ENST00000553458(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004491"("methylmalonate-semialdehyde dehydrogenase (acylating) activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006210"(thymine catabolic process)|go:"GO:0006573"(valine metabolic process)|go:"GO:0006574"(valine catabolic process)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0018478"("malonate-semialdehyde dehydrogenase (acetylating) activity")|go:"GO:0019859"(thymine metabolic process)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0102662"("malonate-semialdehyde dehydrogenase (acetylating, NAD+) activity")|interpro:IPR010061(Methylmalonate-semialdehyde dehydrogenase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|mint:Q02252|reactome:R-HSA-70895 go:"GO:0005739"(mitochondrion) - - figure legend:Figs. 3B, 3C, Supp. Table 10|variable_condition:Low|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/11/12 2014/10/16 rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606 rogid:9tRJSF7S26Z8N2WYcURXRoOLfFw9606 intact-crc:FAFA60AAE2300E2C|rigid:1Y+z12jpGPr+glnid3lWFNZAizg false his tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q7L0Y3 uniprotkb:Q14554 intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356 intact:EBI-953879|ensembl:ENSP00000323313|uniprotkb:D3DN95|uniprotkb:Q9BV43 psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym) psi-mi:pdia5_human(display_long)|uniprotkb:Protein disulfide isomerase-related protein(gene name synonym)|uniprotkb:PDIA5(gene name)|psi-mi:PDIA5(display_short)|uniprotkb:PDIR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2107075|imex:IM-12139-2 author score:Low psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766 ensembl:ENSG00000065485(gene)|ensembl:ENST00000316218(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022900"(electron transport chain)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|interpro:IPR041865|rcsb pdb:4I6X|reactome:R-HSA-381038|refseq:NP_006801.1 go:"GO:0005739"(mitochondrion) - - figure legend:Figs. 3B, 3C, Supp. Table 10|variable_condition:Low|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/11/12 2014/10/16 rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606 rogid:HhJNzAyAeysPEGdQL3Cz0piSjAM9606 intact-crc:FAFA60AAE2300E2C|rigid:1Y+z12jpGPr+glnid3lWFNZAizg false his tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q7L0Y3 uniprotkb:P49411 intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356 intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439 psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym) psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2107075|imex:IM-12139-2 author score:Low psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766 refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1 go:"GO:0005739"(mitochondrion) - - figure legend:Figs. 3B, 3C, Supp. Table 10|variable_condition:Low|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/11/12 2014/10/16 rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606 rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606 intact-crc:FAFA60AAE2300E2C|rigid:1Y+z12jpGPr+glnid3lWFNZAizg false his tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q7L0Y3 uniprotkb:Q9BW19 intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356 intact:EBI-2107279|uniprotkb:O60887|uniprotkb:Q14834|uniprotkb:Q4KMP0|uniprotkb:Q5SU09|uniprotkb:Q6GMS7|uniprotkb:Q6P4A5|uniprotkb:Q9UQP7|ensembl:ENSP00000363647|ensembl:ENSP00000393963|ensembl:ENSP00000407885 psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym) psi-mi:kifc1_human(display_long)|uniprotkb:KIFC1(gene name)|psi-mi:KIFC1(display_short)|uniprotkb:HSET(gene name synonym)|uniprotkb:KNSL2(gene name synonym)|uniprotkb:Kinesin-like protein 2(gene name synonym)|uniprotkb:Kinesin-related protein HSET(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2107075|imex:IM-12139-2 author score:Low psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766 refseq:NP_002254.2|ensembl:ENSG00000204197(gene)|ensembl:ENSG00000233450(gene)|ensembl:ENSG00000237649(gene)|ensembl:ENST00000374523(transcript)|ensembl:ENST00000428849(transcript)|ensembl:ENST00000448818(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|mint:Q9BW19|rcsb pdb:5WDH|reactome:R-HSA-6811434|reactome:R-HSA-983189 go:"GO:0005739"(mitochondrion) - - figure legend:Figs. 3B, 3C, Supp. Table 10|variable_condition:Low|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/11/12 2014/10/16 rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606 rogid:2gWpNwZk9kWJGVvR8xLuDPJYP4M9606 intact-crc:FAFA60AAE2300E2C|rigid:1Y+z12jpGPr+glnid3lWFNZAizg false his tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q7L0Y3 uniprotkb:P34897 intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356 intact:EBI-352908|ensembl:ENSP00000333667|uniprotkb:O00740|uniprotkb:Q8N1A5|uniprotkb:B7Z9F1|uniprotkb:E7EQ19|uniprotkb:E7EU43 psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym) psi-mi:glym_human(display_long)|uniprotkb:SHMT2(gene name)|psi-mi:SHMT2(display_short)|uniprotkb:Glycine hydroxymethyltransferase(gene name synonym)|uniprotkb:Serine methylase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2107075|imex:IM-12139-2 author score:Low psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766 ensembl:ENSG00000182199(gene)|ensembl:ENST00000328923(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008732"(L-allo-threonine aldolase activity)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0034340"(response to type I interferon)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070552"(BRISC complex)|go:"GO:0070905"(serine binding)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|mint:P34897|rcsb pdb:4PVF|rcsb pdb:5V7I|rcsb pdb:5X3V|rcsb pdb:6DK3|rcsb pdb:6H3C|rcsb pdb:6M5O|rcsb pdb:6QVG|rcsb pdb:6QVL|rcsb pdb:6R8F|reactome:R-HSA-196757|reactome:R-HSA-9013408|refseq:NP_001159829.1|refseq:NP_001159830.1|refseq:NP_001159831.1|refseq:NP_005403.2|refseq:NP_001159828.1 go:"GO:0005739"(mitochondrion) - - figure legend:Figs. 3B, 3C, Supp. Table 10|variable_condition:Low|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/11/12 2014/10/16 rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606 rogid:Ce7izVDbUDULaGUe2fZWlikUZFk9606 intact-crc:FAFA60AAE2300E2C|rigid:1Y+z12jpGPr+glnid3lWFNZAizg false his tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q7L0Y3 uniprotkb:P62495 intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356 intact:EBI-750990|intact:EBI-1047744|uniprotkb:B2R6B4|uniprotkb:D3DQC1|uniprotkb:P46055|uniprotkb:Q5M7Z7|uniprotkb:Q96CG1|ensembl:ENSP00000353741 psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym) psi-mi:erf1_human(display_long)|uniprotkb:ETF1(gene name)|psi-mi:ETF1(display_short)|uniprotkb:ERF1(gene name synonym)|uniprotkb:Protein Cl1(gene name synonym)|uniprotkb:RF1(gene name synonym)|uniprotkb:SUP45L1(gene name synonym)|uniprotkb:TB3-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2107075|imex:IM-12139-2 author score:Low psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766 refseq:NP_004721.1|refseq:NP_001243231.1|refseq:NP_001278903.1|refseq:NP_001278904.1|refseq:XP_005271978.1|ensembl:ENSG00000120705(gene)|ensembl:ENST00000360541(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0002184"(cytoplasmic translational termination)|go:"GO:0003723"(RNA binding)|go:"GO:0003747"(translation release factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006415"(translational termination)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006479"(protein methylation)|go:"GO:0008079"(translation termination factor activity)|go:"GO:0016149"(translation release factor activity, codon specific)|go:"GO:0018444"(translation release factor complex)|go:"GO:0043022"(ribosome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR004403(Peptide chain release factor eRF/aRF subunit 1)|interpro:IPR005140(eRF1 domain 1)|interpro:IPR005141(eRF1 domain 2)|interpro:IPR005142(eRF1 domain 3)|interpro:IPR024049|interpro:IPR029064|interpro:IPR042226|mint:P62495|rcsb pdb:1DT9|rcsb pdb:2HST|rcsb pdb:2KTU|rcsb pdb:2KTV|rcsb pdb:2LGT|rcsb pdb:2LLX|rcsb pdb:2MQ6|rcsb pdb:2MQ9|rcsb pdb:3E1Y|rcsb pdb:3J5Y|rcsb pdb:3JAG|rcsb pdb:3JAH|rcsb pdb:3JAI|rcsb pdb:4D5N|rcsb pdb:4D61|rcsb pdb:5A8L|rcsb pdb:5LZT|rcsb pdb:5LZU|rcsb pdb:5LZV|rcsb pdb:6D90|rcsb pdb:6IP8|rcsb pdb:6XA1|rcsb pdb:6ZME|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957 go:"GO:0005739"(mitochondrion) - - figure legend:Figs. 3B, 3C, Supp. Table 10|variable_condition:Low|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/11/12 2014/10/16 rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606 rogid:vUI2Eq2wx++5VxZ2MK1EQ0jnWMI9606 intact-crc:FAFA60AAE2300E2C|rigid:1Y+z12jpGPr+glnid3lWFNZAizg false his tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q7L0Y3 uniprotkb:O15091 intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356 intact:EBI-2107070|ensembl:ENSP00000440915|uniprotkb:D3DS99|uniprotkb:D3DSA1|uniprotkb:B4DXD9|uniprotkb:B4E0S8|uniprotkb:B4E211|uniprotkb:Q86SZ4|uniprotkb:Q86YB5|uniprotkb:Q8N5L5|uniprotkb:C4AM93 psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym) psi-mi:mrpp3_human(display_long)|uniprotkb:PRORP(gene name)|psi-mi:PRORP(display_short)|uniprotkb:KIAA0391(gene name synonym)|uniprotkb:MRPP3(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 3(gene name synonym)|uniprotkb:Protein only RNase P catalytic subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2107075|imex:IM-12139-2 author score:Low psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766 ensembl:ENSG00000100890(gene)|ensembl:ENST00000534898(transcript)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR031595|interpro:IPR033495|mint:O15091|refseq:XP_011535711.1|refseq:XP_011535712.1|refseq:NP_055487.2|refseq:NP_001243607.1|refseq:NP_001243608.1|refseq:NP_001243609.1|refseq:NP_001243610.1|refseq:XP_005268294.1|refseq:XP_016877324.1|refseq:XP_016877325.1|refseq:XP_016877326.1|rcsb pdb:4ROU|rcsb pdb:4XGL|rcsb pdb:4XGM|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766 go:"GO:0005739"(mitochondrion) - - figure legend:Figs. 3B, 3C, Supp. Table 10|variable_condition:Low|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/11/12 2014/10/16 rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606 rogid:ecyf1CIBRAhf7Fgt7+UfnVcNHfs9606 intact-crc:FAFA60AAE2300E2C|rigid:1Y+z12jpGPr+glnid3lWFNZAizg false his tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q99714 uniprotkb:Q7L0Y3 intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9 intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356 psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym) psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2313508|imex:IM-12139-1 author score:High - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1 refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766 go:"GO:0005739"(mitochondrion) - - figure legend:Figs. 2C, 2D|variable_condition:High|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/11/12 2014/10/16 rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606 rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606 intact-crc:466574E66F58DAE5|rigid:wAVYN0xoUjcmdZPdfMOOg4yei1s false - flag tag:c-c - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q99714 uniprotkb:O15091 intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9 intact:EBI-2107070|ensembl:ENSP00000440915|uniprotkb:D3DS99|uniprotkb:D3DSA1|uniprotkb:B4DXD9|uniprotkb:B4E0S8|uniprotkb:B4E211|uniprotkb:Q86SZ4|uniprotkb:Q86YB5|uniprotkb:Q8N5L5|uniprotkb:C4AM93 psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym) psi-mi:mrpp3_human(display_long)|uniprotkb:PRORP(gene name)|psi-mi:PRORP(display_short)|uniprotkb:KIAA0391(gene name synonym)|uniprotkb:MRPP3(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 3(gene name synonym)|uniprotkb:Protein only RNase P catalytic subunit(gene name synonym) psi-mi:"MI:0920"(ribonuclease assay) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0902"(rna cleavage) psi-mi:"MI:0469"(IntAct) intact:EBI-2107101|imex:IM-12139-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1 ensembl:ENSG00000100890(gene)|ensembl:ENST00000534898(transcript)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR031595|interpro:IPR033495|mint:O15091|refseq:XP_011535711.1|refseq:XP_011535712.1|refseq:NP_055487.2|refseq:NP_001243607.1|refseq:NP_001243608.1|refseq:NP_001243609.1|refseq:NP_001243610.1|refseq:XP_005268294.1|refseq:XP_016877324.1|refseq:XP_016877325.1|refseq:XP_016877326.1|rcsb pdb:4ROU|rcsb pdb:4XGL|rcsb pdb:4XGM|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766 go:"GO:0005739"(mitochondrion)|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0004526"(ribonuclease P activity) - - figure legend:Fig. 4B|comment:O15091/KIAA0391 has been tentatively identified as the catalytic subunit by the authors.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/11/12 2014/10/16 rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606 rogid:ecyf1CIBRAhf7Fgt7+UfnVcNHfs9606 intact-crc:9AA015A700009544 false his tag:n-n his tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99714 intact:EBI-2107092 intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9 ensembl:ENSG00000210144 psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym) psi-mi:mt-trna_tyr_rna(display_short)|psi-mi:EBI-2107092(display_long) psi-mi:"MI:0920"(ribonuclease assay) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0902"(rna cleavage) psi-mi:"MI:0469"(IntAct) intact:EBI-2107101|imex:IM-12139-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0325"(transfer rna) rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1 - go:"GO:0005739"(mitochondrion)|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0004526"(ribonuclease P activity) - comment:Ensembl ID only predicted tRNA in region given by authors - 5792 to 5931 of the human mitochondrial genome figure legend:Fig. 4B|comment:O15091/KIAA0391 has been tentatively identified as the catalytic subunit by the authors.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/11/12 2014/10/16 rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606 - intact-crc:9AA015A700009544 false his tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99714 uniprotkb:Q7L0Y3 intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9 intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356 psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym) psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym) psi-mi:"MI:0920"(ribonuclease assay) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0902"(rna cleavage) psi-mi:"MI:0469"(IntAct) intact:EBI-2107101|imex:IM-12139-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1 refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766 go:"GO:0005739"(mitochondrion)|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0004526"(ribonuclease P activity) - - figure legend:Fig. 4B|comment:O15091/KIAA0391 has been tentatively identified as the catalytic subunit by the authors.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/11/12 2014/10/16 rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606 rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606 intact-crc:9AA015A700009544 false his tag:n-n his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99714 uniprotkb:O15091 intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9 intact:EBI-2107070|ensembl:ENSP00000440915|uniprotkb:D3DS99|uniprotkb:D3DSA1|uniprotkb:B4DXD9|uniprotkb:B4E0S8|uniprotkb:B4E211|uniprotkb:Q86SZ4|uniprotkb:Q86YB5|uniprotkb:Q8N5L5|uniprotkb:C4AM93 psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym) psi-mi:mrpp3_human(display_long)|uniprotkb:PRORP(gene name)|psi-mi:PRORP(display_short)|uniprotkb:KIAA0391(gene name synonym)|uniprotkb:MRPP3(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 3(gene name synonym)|uniprotkb:Protein only RNase P catalytic subunit(gene name synonym) psi-mi:"MI:0920"(ribonuclease assay) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0902"(rna cleavage) psi-mi:"MI:0469"(IntAct) intact:EBI-2107195|imex:IM-12139-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1 ensembl:ENSG00000100890(gene)|ensembl:ENST00000534898(transcript)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR031595|interpro:IPR033495|mint:O15091|refseq:XP_011535711.1|refseq:XP_011535712.1|refseq:NP_055487.2|refseq:NP_001243607.1|refseq:NP_001243608.1|refseq:NP_001243609.1|refseq:NP_001243610.1|refseq:XP_005268294.1|refseq:XP_016877324.1|refseq:XP_016877325.1|refseq:XP_016877326.1|rcsb pdb:4ROU|rcsb pdb:4XGL|rcsb pdb:4XGM|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766 go:"GO:0005739"(mitochondrion)|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0004526"(ribonuclease P activity) - - figure legend:Fig. 4C|comment:O15091/KIAA0391 has been tentatively identified as the catalytic subunit by the authors.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/11/12 2014/10/16 rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606 rogid:ecyf1CIBRAhf7Fgt7+UfnVcNHfs9606 intact-crc:01D620DCB8F5FD3F false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99714 intact:EBI-2107192 intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9 ensembl:ENSG00000210100 psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym) psi-mi:mttrna_ile_rna(display_short)|psi-mi:EBI-2107192(display_long) psi-mi:"MI:0920"(ribonuclease assay) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0902"(rna cleavage) psi-mi:"MI:0469"(IntAct) intact:EBI-2107195|imex:IM-12139-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0325"(transfer rna) rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1 - go:"GO:0005739"(mitochondrion)|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0004526"(ribonuclease P activity) - comment:Ensembl cross-reference selected as having the nearest match to the author description of nucleotides 4235 to 4350 of the human mitochondrial genome figure legend:Fig. 4C|comment:O15091/KIAA0391 has been tentatively identified as the catalytic subunit by the authors.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/11/12 2014/10/16 rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606 - intact-crc:01D620DCB8F5FD3F false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99714 uniprotkb:Q7L0Y3 intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9 intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356 psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym) psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym) psi-mi:"MI:0920"(ribonuclease assay) Holzmann et al. (2008) imex:IM-12139|pubmed:18984158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0902"(rna cleavage) psi-mi:"MI:0469"(IntAct) intact:EBI-2107195|imex:IM-12139-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1 refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766 go:"GO:0005739"(mitochondrion)|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0004526"(ribonuclease P activity) - - figure legend:Fig. 4C|comment:O15091/KIAA0391 has been tentatively identified as the catalytic subunit by the authors.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/11/12 2014/10/16 rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606 rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606 intact-crc:01D620DCB8F5FD3F false - flag tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)