#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q12502	uniprotkb:P39940	intact:EBI-2113927|uniprotkb:D6W320|ensemblfungi:YOR322C	intact:EBI-16219|ensemblfungi:YER125W|uniprotkb:D3DM31	psi-mi:ldb19_yeast(display_long)|uniprotkb:LDB19(gene name)|psi-mi:LDB19(display_short)|uniprotkb:Low dye-binding protein 19(gene name synonym)|uniprotkb:O6152(orf name)|uniprotkb:YOR322C(locus name)	psi-mi:rsp5_yeast(display_long)|uniprotkb:RSP5(gene name)|psi-mi:RSP5(display_short)|uniprotkb:MDP1(gene name synonym)|uniprotkb:NPI1(gene name synonym)|uniprotkb:YER125W(locus name)|uniprotkb:SYGP-ORF41(orf name)|uniprotkb:Reverses SPT-phenotype protein 5(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase RSP5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lin et al. (2008)	imex:IM-12144|pubmed:18976803	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2113920|imex:IM-12144-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005849|interpro:IPR024391|refseq:NP_014967.3|interpro:IPR014752(Arrestin, C-terminal)|mint:Q12502|ensemblfungi:YOR322C(gene)|ensemblfungi:YOR322C_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070086"(ubiquitin-dependent endocytosis)	ensemblfungi:YER125W(gene)|ensemblfungi:YER125W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0010794"(regulation of dolichol biosynthetic process)|go:"GO:0010795"(regulation of ubiquinone biosynthetic process)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0019220"(regulation of phosphate metabolic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031384"(regulation of initiation of mating projection growth)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032443"(regulation of ergosterol biosynthetic process)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034517"(ribophagy)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042493"|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:2000203"(regulation of ribosomal large subunit export from nucleus)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2000235"(regulation of tRNA processing)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:2000238"(regulation of tRNA export from nucleus)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|rcsb pdb:3OLM|rcsb pdb:4LCD|rcsb pdb:5HPL|reactome:R-SCE-1169408|reactome:R-SCE-8948751|reactome:R-SCE-9013406|reactome:R-SCE-983168|sgd:S000000927|refseq:NP_011051.3|dip:DIP-2238N|mint:P39940	psi-mi:"MI:0469"(intact)	-	crc64:6F1836384479E70F	figure legend:Fig. 2E|comment:Coordinates of WW domain of RSP5 not given in paper so inferred from UniProtKB entry|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/11/19	2014/10/16	rogid:m4GfOdYCaWsuz8vB1knopv8emXw559292	rogid:IoFCQz3aNFApg/LSyc6Si4dsDc0559292	intact-crc:E1BF08D06D30A549|rigid:J7C/62gZRbtb/TdKwgdbt7Le68g	false	35s radiolabel:?-?|mutation disrupting interaction:690-690,692-692,679-679,681-681|mutation decreasing interaction:679-679,681-681|mutation decreasing interaction:690-690,692-692	glutathione s tranferase tag:?-?|sufficient binding region:229..229-420..420(IPR001202)	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q12502	uniprotkb:P50276	intact:EBI-2113927|uniprotkb:D6W320|ensemblfungi:YOR322C	intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0	psi-mi:ldb19_yeast(display_long)|uniprotkb:LDB19(gene name)|psi-mi:LDB19(display_short)|uniprotkb:Low dye-binding protein 19(gene name synonym)|uniprotkb:O6152(orf name)|uniprotkb:YOR322C(locus name)	psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name)	psi-mi:"MI:0030"(cross-linking study)	Lin et al. (2008)	imex:IM-12144|pubmed:18976803	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2113965|imex:IM-12144-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005849|interpro:IPR024391|refseq:NP_014967.3|interpro:IPR014752(Arrestin, C-terminal)|mint:Q12502|ensemblfungi:YOR322C(gene)|ensemblfungi:YOR322C_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070086"(ubiquitin-dependent endocytosis)	ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 4E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/11/19	2014/10/16	rogid:m4GfOdYCaWsuz8vB1knopv8emXw559292	rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292	intact-crc:902F266438284D91|rigid:l/701z6v+Pghc+r4dtZS5AgVrNU	false	ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q12502	uniprotkb:P39940	intact:EBI-2113927|uniprotkb:D6W320|ensemblfungi:YOR322C	intact:EBI-16219|ensemblfungi:YER125W|uniprotkb:D3DM31	psi-mi:ldb19_yeast(display_long)|uniprotkb:LDB19(gene name)|psi-mi:LDB19(display_short)|uniprotkb:Low dye-binding protein 19(gene name synonym)|uniprotkb:O6152(orf name)|uniprotkb:YOR322C(locus name)	psi-mi:rsp5_yeast(display_long)|uniprotkb:RSP5(gene name)|psi-mi:RSP5(display_short)|uniprotkb:MDP1(gene name synonym)|uniprotkb:NPI1(gene name synonym)|uniprotkb:YER125W(locus name)|uniprotkb:SYGP-ORF41(orf name)|uniprotkb:Reverses SPT-phenotype protein 5(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase RSP5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lin et al. (2008)	imex:IM-12144|pubmed:18976803	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2113974|imex:IM-12144-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005849|interpro:IPR024391|refseq:NP_014967.3|interpro:IPR014752(Arrestin, C-terminal)|mint:Q12502|ensemblfungi:YOR322C(gene)|ensemblfungi:YOR322C_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070086"(ubiquitin-dependent endocytosis)	ensemblfungi:YER125W(gene)|ensemblfungi:YER125W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0010794"(regulation of dolichol biosynthetic process)|go:"GO:0010795"(regulation of ubiquinone biosynthetic process)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0019220"(regulation of phosphate metabolic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031384"(regulation of initiation of mating projection growth)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032443"(regulation of ergosterol biosynthetic process)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034517"(ribophagy)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042493"|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:2000203"(regulation of ribosomal large subunit export from nucleus)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2000235"(regulation of tRNA processing)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:2000238"(regulation of tRNA export from nucleus)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|rcsb pdb:3OLM|rcsb pdb:4LCD|rcsb pdb:5HPL|reactome:R-SCE-1169408|reactome:R-SCE-8948751|reactome:R-SCE-9013406|reactome:R-SCE-983168|sgd:S000000927|refseq:NP_011051.3|dip:DIP-2238N|mint:P39940	psi-mi:"MI:0469"(intact)	-	crc64:6F1836384479E70F	figure legend:Fig. 5B|caution:Coordinates of WW domain of RSP5 not given in paper so inferred from UniProtKB entry|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/11/19	2014/10/16	rogid:m4GfOdYCaWsuz8vB1knopv8emXw559292	rogid:IoFCQz3aNFApg/LSyc6Si4dsDc0559292	intact-crc:B9452BA5C1DA77CD|rigid:J7C/62gZRbtb/TdKwgdbt7Le68g	false	necessary binding region:397-818|flag tag:?-?	glutathione s tranferase tag:?-?|sufficient binding region:229..229-420..420(IPR001202)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P39940	uniprotkb:P38167	intact:EBI-16219|ensemblfungi:YER125W|uniprotkb:D3DM31	intact:EBI-21359|uniprotkb:D6VPQ2|ensemblfungi:YBL101C	psi-mi:rsp5_yeast(display_long)|uniprotkb:RSP5(gene name)|psi-mi:RSP5(display_short)|uniprotkb:MDP1(gene name synonym)|uniprotkb:NPI1(gene name synonym)|uniprotkb:YER125W(locus name)|uniprotkb:SYGP-ORF41(orf name)|uniprotkb:Reverses SPT-phenotype protein 5(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase RSP5(gene name synonym)	psi-mi:ecm21_yeast(display_long)|uniprotkb:YBL101C(locus name)|uniprotkb:YBL0814(orf name)|uniprotkb:ECM21(gene name)|psi-mi:ECM21(display_short)|uniprotkb:Extracellular mutant protein 21(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lin et al. (2008)	imex:IM-12144|pubmed:18976803	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2114163|imex:IM-12144-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YER125W(gene)|ensemblfungi:YER125W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0010794"(regulation of dolichol biosynthetic process)|go:"GO:0010795"(regulation of ubiquinone biosynthetic process)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0019220"(regulation of phosphate metabolic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031384"(regulation of initiation of mating projection growth)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032443"(regulation of ergosterol biosynthetic process)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034517"(ribophagy)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042493"|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:2000203"(regulation of ribosomal large subunit export from nucleus)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2000235"(regulation of tRNA processing)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:2000238"(regulation of tRNA export from nucleus)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|rcsb pdb:3OLM|rcsb pdb:4LCD|rcsb pdb:5HPL|reactome:R-SCE-1169408|reactome:R-SCE-8948751|reactome:R-SCE-9013406|reactome:R-SCE-983168|sgd:S000000927|refseq:NP_011051.3|dip:DIP-2238N|mint:P39940	refseq:NP_009449.1|sgd:S000000197|mint:P38167|dip:DIP-791N|ensemblfungi:YBL101C(gene)|ensemblfungi:YBL101C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:0071555"(cell wall organization)|interpro:IPR011022(Arrestin-like, C-terminal)	psi-mi:"MI:0469"(intact)	crc64:6F1836384479E70F	-	figure legend:Fig. 5B|caution:Coordinates of WW domain of RSP5 not given in paper so inferred from UniProtKB entry|caution:A c-terminal fragment of ecm21 was required to bind but the coordinates were not given in the entry|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/11/19	2014/10/16	rogid:IoFCQz3aNFApg/LSyc6Si4dsDc0559292	rogid:QZYFcUGl4kmJOxb5Cus+sulNaX4559292	intact-crc:974EC56A0121A154|rigid:dcrLVbfG+eX+OyNEitjgk1nM890	false	glutathione s tranferase tag:?-?|sufficient binding region:229..229-420..420(IPR001202)	flag tag:?-?|sufficient binding region:?-1117	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P47029	uniprotkb:P39940	intact:EBI-25974|uniprotkb:Q05742|uniprotkb:D6VW99|ensemblfungi:YJL084C	intact:EBI-16219|ensemblfungi:YER125W|uniprotkb:D3DM31	psi-mi:aly2_yeast(display_long)|uniprotkb:ART3(gene name synonym)|uniprotkb:J0934(orf name)|uniprotkb:YJL084C(locus name)|uniprotkb:ALY2(gene name)|psi-mi:ALY2(display_short)|uniprotkb:Arrestin-like protein 2(gene name synonym)	psi-mi:rsp5_yeast(display_long)|uniprotkb:RSP5(gene name)|psi-mi:RSP5(display_short)|uniprotkb:MDP1(gene name synonym)|uniprotkb:NPI1(gene name synonym)|uniprotkb:YER125W(locus name)|uniprotkb:SYGP-ORF41(orf name)|uniprotkb:Reverses SPT-phenotype protein 5(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase RSP5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lin et al. (2008)	imex:IM-12144|pubmed:18976803	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2114272|imex:IM-12144-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012451.1|sgd:S000003620|mint:P47029|dip:DIP-1497N|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|ensemblfungi:YJL084C(gene)|ensemblfungi:YJL084C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)	ensemblfungi:YER125W(gene)|ensemblfungi:YER125W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0010794"(regulation of dolichol biosynthetic process)|go:"GO:0010795"(regulation of ubiquinone biosynthetic process)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0019220"(regulation of phosphate metabolic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031384"(regulation of initiation of mating projection growth)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032443"(regulation of ergosterol biosynthetic process)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034517"(ribophagy)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042493"|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:2000203"(regulation of ribosomal large subunit export from nucleus)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2000235"(regulation of tRNA processing)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:2000238"(regulation of tRNA export from nucleus)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|rcsb pdb:3OLM|rcsb pdb:4LCD|rcsb pdb:5HPL|reactome:R-SCE-1169408|reactome:R-SCE-8948751|reactome:R-SCE-9013406|reactome:R-SCE-983168|sgd:S000000927|refseq:NP_011051.3|dip:DIP-2238N|mint:P39940	psi-mi:"MI:0469"(intact)	-	crc64:6F1836384479E70F	figure legend:Fig. 5B|caution:Coordinates of WW domain of RSP5 not given in paper so inferred from UniProtKB entry|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/11/19	2014/10/16	rogid:sfmg4+QNtUMFgGqKkQAb+FteTrc559292	rogid:IoFCQz3aNFApg/LSyc6Si4dsDc0559292	intact-crc:23E9B4D97A6863AA|rigid:gL+Q04EL0l+6PD0m00SlfG1JwW8	false	flag tag:?-?	glutathione s tranferase tag:?-?|sufficient binding region:229..229-420..420(IPR001202)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q02805	uniprotkb:P39940	intact:EBI-15679|uniprotkb:D6W284|uniprotkb:Q12475|ensemblfungi:YOR018W	intact:EBI-16219|ensemblfungi:YER125W|uniprotkb:D3DM31	psi-mi:rod1_yeast(display_long)|uniprotkb:ROD1(gene name)|psi-mi:ROD1(display_short)|uniprotkb:YOR018W(locus name)|uniprotkb:OR26.08(orf name)|uniprotkb:Resistance to o-dinitrobenzene protein 1(gene name synonym)	psi-mi:rsp5_yeast(display_long)|uniprotkb:RSP5(gene name)|psi-mi:RSP5(display_short)|uniprotkb:MDP1(gene name synonym)|uniprotkb:NPI1(gene name synonym)|uniprotkb:YER125W(locus name)|uniprotkb:SYGP-ORF41(orf name)|uniprotkb:Reverses SPT-phenotype protein 5(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase RSP5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lin et al. (2008)	imex:IM-12144|pubmed:18976803	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2114287|imex:IM-12144-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014661.1|sgd:S000005544|ensemblfungi:YOR018W(gene)|ensemblfungi:YOR018W_mRNA(transcript)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042493"|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:0071333"(cellular response to glucose stimulus)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|dip:DIP-4189N|mint:Q02805	ensemblfungi:YER125W(gene)|ensemblfungi:YER125W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0010794"(regulation of dolichol biosynthetic process)|go:"GO:0010795"(regulation of ubiquinone biosynthetic process)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0019220"(regulation of phosphate metabolic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031384"(regulation of initiation of mating projection growth)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032443"(regulation of ergosterol biosynthetic process)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034517"(ribophagy)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042493"|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:2000203"(regulation of ribosomal large subunit export from nucleus)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2000235"(regulation of tRNA processing)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:2000238"(regulation of tRNA export from nucleus)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|rcsb pdb:3OLM|rcsb pdb:4LCD|rcsb pdb:5HPL|reactome:R-SCE-1169408|reactome:R-SCE-8948751|reactome:R-SCE-9013406|reactome:R-SCE-983168|sgd:S000000927|refseq:NP_011051.3|dip:DIP-2238N|mint:P39940	psi-mi:"MI:0469"(intact)	crc64:FD9A64174B1DC443	crc64:6F1836384479E70F	figure legend:Fig. 5B|caution:Coordinates of WW domain of RSP5 not given in paper so inferred from UniProtKB entry|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/11/19	2014/10/16	rogid:uZvRFKexlh7bpBSPflXIiLXQ910559292	rogid:IoFCQz3aNFApg/LSyc6Si4dsDc0559292	intact-crc:ED821825183726F2|rigid:Q5Qt/b8HbdIRJfXuz0uezxIWpRs	false	flag tag:?-?	glutathione s tranferase tag:?-?|sufficient binding region:229..229-420..420(IPR001202)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P53244	uniprotkb:P39940	intact:EBI-23201|uniprotkb:D6VUK2|ensemblfungi:YGR068C	intact:EBI-16219|ensemblfungi:YER125W|uniprotkb:D3DM31	psi-mi:art5_yeast(display_long)|uniprotkb:YGR068C(locus name)|uniprotkb:ART5(gene name)|psi-mi:ART5(display_short)	psi-mi:rsp5_yeast(display_long)|uniprotkb:RSP5(gene name)|psi-mi:RSP5(display_short)|uniprotkb:MDP1(gene name synonym)|uniprotkb:NPI1(gene name synonym)|uniprotkb:YER125W(locus name)|uniprotkb:SYGP-ORF41(orf name)|uniprotkb:Reverses SPT-phenotype protein 5(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase RSP5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lin et al. (2008)	imex:IM-12144|pubmed:18976803	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2114300|imex:IM-12144-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011582.1|sgd:S000003300|dip:DIP-1864N|mint:P53244|ensemblfungi:YGR068C(gene)|ensemblfungi:YGR068C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|interpro:IPR011022(Arrestin-like, C-terminal)	ensemblfungi:YER125W(gene)|ensemblfungi:YER125W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0010794"(regulation of dolichol biosynthetic process)|go:"GO:0010795"(regulation of ubiquinone biosynthetic process)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0019220"(regulation of phosphate metabolic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031384"(regulation of initiation of mating projection growth)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032443"(regulation of ergosterol biosynthetic process)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034517"(ribophagy)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042493"|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:2000203"(regulation of ribosomal large subunit export from nucleus)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2000235"(regulation of tRNA processing)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:2000238"(regulation of tRNA export from nucleus)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|rcsb pdb:3OLM|rcsb pdb:4LCD|rcsb pdb:5HPL|reactome:R-SCE-1169408|reactome:R-SCE-8948751|reactome:R-SCE-9013406|reactome:R-SCE-983168|sgd:S000000927|refseq:NP_011051.3|dip:DIP-2238N|mint:P39940	psi-mi:"MI:0469"(intact)	-	crc64:6F1836384479E70F	figure legend:Fig. 5B|caution:Coordinates of WW domain of RSP5 not given in paper so inferred from UniProtKB entry|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/11/19	2014/10/16	rogid:LM14yw+sKqbw/B2/ellDDBBMAhc559292	rogid:IoFCQz3aNFApg/LSyc6Si4dsDc0559292	intact-crc:4CF7AF2B66D136A1|rigid:5WT24tHSm4DotQh73wNQZuyA6ds	false	flag tag:?-?	glutathione s tranferase tag:?-?|sufficient binding region:229..229-420..420(IPR001202)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P36117	uniprotkb:P39940	intact:EBI-26358|uniprotkb:D6VX86|ensemblfungi:YKR021W	intact:EBI-16219|ensemblfungi:YER125W|uniprotkb:D3DM31	psi-mi:aly1_yeast(display_long)|uniprotkb:ART6(gene name synonym)|uniprotkb:YKR021W(locus name)|uniprotkb:ALY1(gene name)|psi-mi:ALY1(display_short)|uniprotkb:Arrestin-like protein 1(gene name synonym)	psi-mi:rsp5_yeast(display_long)|uniprotkb:RSP5(gene name)|psi-mi:RSP5(display_short)|uniprotkb:MDP1(gene name synonym)|uniprotkb:NPI1(gene name synonym)|uniprotkb:YER125W(locus name)|uniprotkb:SYGP-ORF41(orf name)|uniprotkb:Reverses SPT-phenotype protein 5(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase RSP5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lin et al. (2008)	imex:IM-12144|pubmed:18976803	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2114372|imex:IM-12144-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001729|refseq:NP_012946.3|dip:DIP-2615N|ensemblfungi:YKR021W(gene)|ensemblfungi:YKR021W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005770"(late endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)	ensemblfungi:YER125W(gene)|ensemblfungi:YER125W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0010794"(regulation of dolichol biosynthetic process)|go:"GO:0010795"(regulation of ubiquinone biosynthetic process)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0019220"(regulation of phosphate metabolic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031384"(regulation of initiation of mating projection growth)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032443"(regulation of ergosterol biosynthetic process)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034517"(ribophagy)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042493"|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:2000203"(regulation of ribosomal large subunit export from nucleus)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2000235"(regulation of tRNA processing)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:2000238"(regulation of tRNA export from nucleus)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|rcsb pdb:3OLM|rcsb pdb:4LCD|rcsb pdb:5HPL|reactome:R-SCE-1169408|reactome:R-SCE-8948751|reactome:R-SCE-9013406|reactome:R-SCE-983168|sgd:S000000927|refseq:NP_011051.3|dip:DIP-2238N|mint:P39940	psi-mi:"MI:0469"(intact)	-	crc64:6F1836384479E70F	figure legend:Fig. 5B|caution:Coordinates of WW domain of RSP5 not given in paper so inferred from UniProtKB entry|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/11/19	2014/10/16	rogid:P83RTgZTUfEu+3BafncFgUW0fg0559292	rogid:IoFCQz3aNFApg/LSyc6Si4dsDc0559292	intact-crc:4F01001298AE3CE8|rigid:gPM/x31CBW74UXP3J2S6g4g5iQs	false	flag tag:?-?	glutathione s tranferase tag:?-?|sufficient binding region:229..229-420..420(IPR001202)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P39940	uniprotkb:P43602	intact:EBI-16219|ensemblfungi:YER125W|uniprotkb:D3DM31	intact:EBI-22976|uniprotkb:D6VTQ2|ensemblfungi:YFR022W	psi-mi:rsp5_yeast(display_long)|uniprotkb:RSP5(gene name)|psi-mi:RSP5(display_short)|uniprotkb:MDP1(gene name synonym)|uniprotkb:NPI1(gene name synonym)|uniprotkb:YER125W(locus name)|uniprotkb:SYGP-ORF41(orf name)|uniprotkb:Reverses SPT-phenotype protein 5(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase RSP5(gene name synonym)	psi-mi:rog3_yeast(display_long)|uniprotkb:YFR022W(locus name)|uniprotkb:ROG3(gene name)|psi-mi:ROG3(display_short)|uniprotkb:Revertant of glycogen synthase kinase mutation protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lin et al. (2008)	imex:IM-12144|pubmed:18976803	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2114408|imex:IM-12144-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YER125W(gene)|ensemblfungi:YER125W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0010794"(regulation of dolichol biosynthetic process)|go:"GO:0010795"(regulation of ubiquinone biosynthetic process)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0019220"(regulation of phosphate metabolic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031384"(regulation of initiation of mating projection growth)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032443"(regulation of ergosterol biosynthetic process)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034517"(ribophagy)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042493"|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:2000203"(regulation of ribosomal large subunit export from nucleus)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2000235"(regulation of tRNA processing)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:2000238"(regulation of tRNA export from nucleus)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|rcsb pdb:3OLM|rcsb pdb:4LCD|rcsb pdb:5HPL|reactome:R-SCE-1169408|reactome:R-SCE-8948751|reactome:R-SCE-9013406|reactome:R-SCE-983168|sgd:S000000927|refseq:NP_011051.3|dip:DIP-2238N|mint:P39940	sgd:S000001918|refseq:NP_116677.3|dip:DIP-4111N|mint:P43602|ensemblfungi:YFR022W(gene)|ensemblfungi:YFR022W_mRNA(transcript)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)	psi-mi:"MI:0469"(intact)	crc64:6F1836384479E70F	-	figure legend:Fig. 5B|caution:Coordinates of WW domain of RSP5 not given in paper so inferred from UniProtKB entry|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/11/19	2014/10/16	rogid:IoFCQz3aNFApg/LSyc6Si4dsDc0559292	rogid:+VJcW9XRJcuxMTGuwS83FLsnYKU559292	intact-crc:641B41F52CACD403|rigid:2KgCc0m47+huvktfwhAb6P34ZE0	false	sufficient binding region:229..229-420..420(IPR001202)|glutathione s tranferase tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P39940	uniprotkb:Q12734	intact:EBI-16219|ensemblfungi:YER125W|uniprotkb:D3DM31	intact:EBI-32379|uniprotkb:D6W440|ensemblfungi:YPR030W	psi-mi:rsp5_yeast(display_long)|uniprotkb:RSP5(gene name)|psi-mi:RSP5(display_short)|uniprotkb:MDP1(gene name synonym)|uniprotkb:NPI1(gene name synonym)|uniprotkb:YER125W(locus name)|uniprotkb:SYGP-ORF41(orf name)|uniprotkb:Reverses SPT-phenotype protein 5(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase RSP5(gene name synonym)	psi-mi:csr2_yeast(display_long)|uniprotkb:CHS5 SPA2 rescue protein 2(gene name synonym)|uniprotkb:CSR2(gene name)|psi-mi:CSR2(display_short)|uniprotkb:MRG19(gene name synonym)|uniprotkb:YP9367.10(orf name)|uniprotkb:YPR030W(locus name)	psi-mi:"MI:0096"(pull down)	Lin et al. (2008)	imex:IM-12144|pubmed:18976803	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2114431|imex:IM-12144-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YER125W(gene)|ensemblfungi:YER125W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0010794"(regulation of dolichol biosynthetic process)|go:"GO:0010795"(regulation of ubiquinone biosynthetic process)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0019220"(regulation of phosphate metabolic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031384"(regulation of initiation of mating projection growth)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032443"(regulation of ergosterol biosynthetic process)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034517"(ribophagy)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042493"|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:2000203"(regulation of ribosomal large subunit export from nucleus)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2000235"(regulation of tRNA processing)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:2000238"(regulation of tRNA export from nucleus)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|rcsb pdb:3OLM|rcsb pdb:4LCD|rcsb pdb:5HPL|reactome:R-SCE-1169408|reactome:R-SCE-8948751|reactome:R-SCE-9013406|reactome:R-SCE-983168|sgd:S000000927|refseq:NP_011051.3|dip:DIP-2238N|mint:P39940	refseq:NP_015355.1|sgd:S000006234|dip:DIP-3911N|mint:Q12734|ensemblfungi:YPR030W(gene)|ensemblfungi:YPR030W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0015031"(protein transport)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|interpro:IPR011022(Arrestin-like, C-terminal)	psi-mi:"MI:0469"(intact)	crc64:6F1836384479E70F	crc64:31F958BB8DB0B7E8	figure legend:Fig. 5B|caution:Coordinates of WW domain of RSP5 not given in paper so inferred from UniProtKB entry|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/11/19	2014/10/16	rogid:IoFCQz3aNFApg/LSyc6Si4dsDc0559292	rogid:CBX47VWLzDX13+X8NkX2oJmIECc559292	intact-crc:00326759D26ADB86|rigid:hmDcPlUP2dEjJJ5GOEwI1JWMA3I	false	sufficient binding region:229..229-420..420(IPR001202)|glutathione s tranferase tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)