#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8RXD6	uniprotkb:Q8RXD6	intact:EBI-2012188|uniprotkb:O22156|uniprotkb:O22157|ensemblplants:AT2G44950.1	intact:EBI-2012188|uniprotkb:O22156|uniprotkb:O22157|ensemblplants:AT2G44950.1	psi-mi:bre1a_arath(display_long)|uniprotkb:HUB1(gene name)|psi-mi:HUB1(display_short)|uniprotkb:BRE1A(gene name synonym)|uniprotkb:Protein HISTONE MONOUBIQUITINATION 1(gene name synonym)|uniprotkb:Protein REDUCED DORMANCY 4(gene name synonym)|uniprotkb:RDO4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1-like 1(gene name synonym)|uniprotkb:T13E15.24/T13E15.23(orf name)|uniprotkb:T14P1.25/T14P1.24(orf name)|uniprotkb:At2g44950/At2g44960(locus name)	psi-mi:bre1a_arath(display_long)|uniprotkb:HUB1(gene name)|psi-mi:HUB1(display_short)|uniprotkb:BRE1A(gene name synonym)|uniprotkb:Protein HISTONE MONOUBIQUITINATION 1(gene name synonym)|uniprotkb:Protein REDUCED DORMANCY 4(gene name synonym)|uniprotkb:RDO4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1-like 1(gene name synonym)|uniprotkb:T13E15.24/T13E15.23(orf name)|uniprotkb:T14P1.25/T14P1.24(orf name)|uniprotkb:At2g44950/At2g44960(locus name)	psi-mi:"MI:0018"(two hybrid)	Cao et al. (2008)	pubmed:18849490|imex:IM-20128	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2012226|imex:IM-20128-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_182022.2|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|ensemblplants:AT2G44950(gene)|ensemblplants:AT2G44950.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0009965"(leaf morphogenesis)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010228"(vegetative to reproductive phase transition of meristem)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051301"(cell division)|go:"GO:0051781"(positive regulation of cell division)	refseq:NP_182022.2|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|ensemblplants:AT2G44950(gene)|ensemblplants:AT2G44950.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0009965"(leaf morphogenesis)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010228"(vegetative to reproductive phase transition of meristem)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051301"(cell division)|go:"GO:0051781"(positive regulation of cell division)	-	-	-	figure legend:Figure 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/10/15	2014/10/16	rogid:n6hz9X+NX9lqeKwVsERMg3FAomw3702	rogid:n6hz9X+NX9lqeKwVsERMg3FAomw3702	intact-crc:0325E989EE962994|rigid:49ijTCm1tLqGKeHwgM2oBIARLy0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9C895	uniprotkb:Q9C895	intact:EBI-2012230|uniprotkb:Q058L1|uniprotkb:Q8LDW7|ensemblplants:AT1G55250.1	intact:EBI-2012230|uniprotkb:Q058L1|uniprotkb:Q8LDW7|ensemblplants:AT1G55250.1	psi-mi:bre1b_arath(display_long)|uniprotkb:HUB2(gene name)|psi-mi:HUB2(display_short)|uniprotkb:BRE1B(gene name synonym)|uniprotkb:Protein HISTONE MONOUBIQUITINATION 2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1-like 2(gene name synonym)|uniprotkb:F7A10.17(orf name)|uniprotkb:At1g55250/At1g55255(locus name)	psi-mi:bre1b_arath(display_long)|uniprotkb:HUB2(gene name)|psi-mi:HUB2(display_short)|uniprotkb:BRE1B(gene name synonym)|uniprotkb:Protein HISTONE MONOUBIQUITINATION 2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1-like 2(gene name synonym)|uniprotkb:F7A10.17(orf name)|uniprotkb:At1g55250/At1g55255(locus name)	psi-mi:"MI:0018"(two hybrid)	Cao et al. (2008)	pubmed:18849490|imex:IM-20128	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2012250|imex:IM-20128-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_564680.4|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|refseq:NP_001154428.1|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|ensemblplants:AT1G55250(gene)|ensemblplants:AT1G55250.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0009965"(leaf morphogenesis)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010228"(vegetative to reproductive phase transition of meristem)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)	refseq:NP_564680.4|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|refseq:NP_001154428.1|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|ensemblplants:AT1G55250(gene)|ensemblplants:AT1G55250.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0009965"(leaf morphogenesis)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010228"(vegetative to reproductive phase transition of meristem)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)	-	-	-	figure legend:Figure 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/10/15	2014/10/16	rogid:GESUJ83OolAEUxbXsnPfEoL3QM83702	rogid:GESUJ83OolAEUxbXsnPfEoL3QM83702	intact-crc:2D0E8896C085B447|rigid:83TGxin27k4rXHwQOYwJLyLzeLE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8RXD6	uniprotkb:Q9C895	intact:EBI-2012188|uniprotkb:O22156|uniprotkb:O22157|ensemblplants:AT2G44950.1	intact:EBI-2012230|uniprotkb:Q058L1|uniprotkb:Q8LDW7|ensemblplants:AT1G55250.1	psi-mi:bre1a_arath(display_long)|uniprotkb:HUB1(gene name)|psi-mi:HUB1(display_short)|uniprotkb:BRE1A(gene name synonym)|uniprotkb:Protein HISTONE MONOUBIQUITINATION 1(gene name synonym)|uniprotkb:Protein REDUCED DORMANCY 4(gene name synonym)|uniprotkb:RDO4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1-like 1(gene name synonym)|uniprotkb:T13E15.24/T13E15.23(orf name)|uniprotkb:T14P1.25/T14P1.24(orf name)|uniprotkb:At2g44950/At2g44960(locus name)	psi-mi:bre1b_arath(display_long)|uniprotkb:HUB2(gene name)|psi-mi:HUB2(display_short)|uniprotkb:BRE1B(gene name synonym)|uniprotkb:Protein HISTONE MONOUBIQUITINATION 2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1-like 2(gene name synonym)|uniprotkb:F7A10.17(orf name)|uniprotkb:At1g55250/At1g55255(locus name)	psi-mi:"MI:0018"(two hybrid)	Cao et al. (2008)	pubmed:18849490|imex:IM-20128	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2012254|imex:IM-20128-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_182022.2|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|ensemblplants:AT2G44950(gene)|ensemblplants:AT2G44950.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0009965"(leaf morphogenesis)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010228"(vegetative to reproductive phase transition of meristem)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051301"(cell division)|go:"GO:0051781"(positive regulation of cell division)	refseq:NP_564680.4|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|refseq:NP_001154428.1|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|ensemblplants:AT1G55250(gene)|ensemblplants:AT1G55250.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0009965"(leaf morphogenesis)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010228"(vegetative to reproductive phase transition of meristem)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)	-	-	-	figure legend:Figure 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/10/15	2014/10/16	rogid:n6hz9X+NX9lqeKwVsERMg3FAomw3702	rogid:GESUJ83OolAEUxbXsnPfEoL3QM83702	intact-crc:AEE31B4F4345D9A3|rigid:P8mlcRKcQpk5T3gHt3UX8DOmJJ8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25865	uniprotkb:Q9C895	intact:EBI-2012506|uniprotkb:Q4TZ08|ensemblplants:AT1G14400.1|ensemblplants:AT1G14400.2	intact:EBI-2012230|uniprotkb:Q058L1|uniprotkb:Q8LDW7|ensemblplants:AT1G55250.1	psi-mi:ubc1_arath(display_long)|uniprotkb:UBC1(gene name)|psi-mi:UBC1(display_short)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:Ubiquitin-protein ligase 1(gene name synonym)|uniprotkb:Ubiquitin carrier protein 1(gene name synonym)|uniprotkb:F14L17.17(orf name)|uniprotkb:F14L17_35(orf name)|uniprotkb:At1g14400(locus name)|uniprotkb:E2 ubiquitin-conjugating enzyme 1(gene name synonym)	psi-mi:bre1b_arath(display_long)|uniprotkb:HUB2(gene name)|psi-mi:HUB2(display_short)|uniprotkb:BRE1B(gene name synonym)|uniprotkb:Protein HISTONE MONOUBIQUITINATION 2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1-like 2(gene name synonym)|uniprotkb:F7A10.17(orf name)|uniprotkb:At1g55250/At1g55255(locus name)	psi-mi:"MI:0018"(two hybrid)	Cao et al. (2008)	pubmed:18849490|imex:IM-20128	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2012522|imex:IM-20128-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_563951.1|refseq:NP_973825.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR023313|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2AAK|ensemblplants:AT1G14400(gene)|ensemblplants:AT1G14400.1(transcript)|ensemblplants:AT1G14400.2(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010228"(vegetative to reproductive phase transition of meristem)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)	refseq:NP_564680.4|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|refseq:NP_001154428.1|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|ensemblplants:AT1G55250(gene)|ensemblplants:AT1G55250.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0009965"(leaf morphogenesis)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010228"(vegetative to reproductive phase transition of meristem)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)	-	-	-	figure legend:Figure 5A|comment:"The authors concluded that the RING finger domain of HUB1 or HUB2 was shown to be necessary for its interactions with UBC1 and UBC2, due to the fact that each interaction was abolished if the RING finger domain was deleted\"."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/10/15	2014/10/16	rogid:EaNCDfjRYzqbgdvTMQuG99UQmjc3702	rogid:GESUJ83OolAEUxbXsnPfEoL3QM83702	intact-crc:D53C2A865A2DB73C|rigid:KuQxUIxLLsOskj8arEctxrTOosw	false	-	necessary binding region:850-900	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25865	uniprotkb:Q8RXD6	intact:EBI-2012506|uniprotkb:Q4TZ08|ensemblplants:AT1G14400.1|ensemblplants:AT1G14400.2	intact:EBI-2012188|uniprotkb:O22156|uniprotkb:O22157|ensemblplants:AT2G44950.1	psi-mi:ubc1_arath(display_long)|uniprotkb:UBC1(gene name)|psi-mi:UBC1(display_short)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:Ubiquitin-protein ligase 1(gene name synonym)|uniprotkb:Ubiquitin carrier protein 1(gene name synonym)|uniprotkb:F14L17.17(orf name)|uniprotkb:F14L17_35(orf name)|uniprotkb:At1g14400(locus name)|uniprotkb:E2 ubiquitin-conjugating enzyme 1(gene name synonym)	psi-mi:bre1a_arath(display_long)|uniprotkb:HUB1(gene name)|psi-mi:HUB1(display_short)|uniprotkb:BRE1A(gene name synonym)|uniprotkb:Protein HISTONE MONOUBIQUITINATION 1(gene name synonym)|uniprotkb:Protein REDUCED DORMANCY 4(gene name synonym)|uniprotkb:RDO4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1-like 1(gene name synonym)|uniprotkb:T13E15.24/T13E15.23(orf name)|uniprotkb:T14P1.25/T14P1.24(orf name)|uniprotkb:At2g44950/At2g44960(locus name)	psi-mi:"MI:0018"(two hybrid)	Cao et al. (2008)	pubmed:18849490|imex:IM-20128	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2012527|imex:IM-20128-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_563951.1|refseq:NP_973825.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR023313|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2AAK|ensemblplants:AT1G14400(gene)|ensemblplants:AT1G14400.1(transcript)|ensemblplants:AT1G14400.2(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010228"(vegetative to reproductive phase transition of meristem)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)	refseq:NP_182022.2|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|ensemblplants:AT2G44950(gene)|ensemblplants:AT2G44950.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0009965"(leaf morphogenesis)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010228"(vegetative to reproductive phase transition of meristem)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051301"(cell division)|go:"GO:0051781"(positive regulation of cell division)	-	-	-	figure legend:Figure 5A Figure 5B|comment:"The authors concluded that the RING finger domain of HUB1 or HUB2 was shown to be necessary for its interactions with UBC1 and UBC2, due to the fact that each interaction was abolished if the RING finger domain was deleted\"."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/10/15	2014/10/16	rogid:EaNCDfjRYzqbgdvTMQuG99UQmjc3702	rogid:n6hz9X+NX9lqeKwVsERMg3FAomw3702	intact-crc:C644C4FC611EF317|rigid:14nsGC/wMi1xLyIKTxh/Oekllyw	false	-	necessary binding region:825-878	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8RXD6	uniprotkb:P42745	intact:EBI-2012188|uniprotkb:O22156|uniprotkb:O22157|ensemblplants:AT2G44950.1	intact:EBI-2012549|uniprotkb:Q4TZ07|ensemblplants:AT2G02760.1|ensemblplants:AT2G02760.2|ensemblplants:AT2G02760.3|ensemblplants:AT2G02760.4	psi-mi:bre1a_arath(display_long)|uniprotkb:HUB1(gene name)|psi-mi:HUB1(display_short)|uniprotkb:BRE1A(gene name synonym)|uniprotkb:Protein HISTONE MONOUBIQUITINATION 1(gene name synonym)|uniprotkb:Protein REDUCED DORMANCY 4(gene name synonym)|uniprotkb:RDO4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1-like 1(gene name synonym)|uniprotkb:T13E15.24/T13E15.23(orf name)|uniprotkb:T14P1.25/T14P1.24(orf name)|uniprotkb:At2g44950/At2g44960(locus name)	psi-mi:ubc2_arath(display_long)|uniprotkb:Ubiquitin-protein ligase 2(gene name synonym)|uniprotkb:Ubiquitin carrier protein 2(gene name synonym)|uniprotkb:T20F6.10(orf name)|uniprotkb:At2g02760(locus name)|uniprotkb:UBC2(gene name)|psi-mi:UBC2(display_short)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Cao et al. (2008)	pubmed:18849490|imex:IM-20128	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2012562|imex:IM-20128-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_182022.2|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|ensemblplants:AT2G44950(gene)|ensemblplants:AT2G44950.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0009965"(leaf morphogenesis)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010228"(vegetative to reproductive phase transition of meristem)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051301"(cell division)|go:"GO:0051781"(positive regulation of cell division)	refseq:NP_565289.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR023313|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001325162.1|refseq:NP_001325163.1|refseq:NP_001325164.1|ensemblplants:AT2G02760(gene)|ensemblplants:AT2G02760.1(transcript)|ensemblplants:AT2G02760.2(transcript)|ensemblplants:AT2G02760.3(transcript)|ensemblplants:AT2G02760.4(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010228"(vegetative to reproductive phase transition of meristem)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)	-	-	-	figure legend:Figure 5A Figure 5B|comment:"The authors concluded that the RING finger domain of HUB1 or HUB2 was shown to be necessary for its interactions with UBC1 and UBC2, due to the fact that each interaction was abolished if the RING finger domain was deleted\"."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/10/15	2014/10/16	rogid:n6hz9X+NX9lqeKwVsERMg3FAomw3702	rogid:aJy6H/gPHLOvtdG9HioNCnGXNH03702	intact-crc:D796FB62A738A08F|rigid:dVh5Gzd3C45gNekKIX7Khs/VNDc	false	necessary binding region:825-878	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9C895	uniprotkb:P42745	intact:EBI-2012230|uniprotkb:Q058L1|uniprotkb:Q8LDW7|ensemblplants:AT1G55250.1	intact:EBI-2012549|uniprotkb:Q4TZ07|ensemblplants:AT2G02760.1|ensemblplants:AT2G02760.2|ensemblplants:AT2G02760.3|ensemblplants:AT2G02760.4	psi-mi:bre1b_arath(display_long)|uniprotkb:HUB2(gene name)|psi-mi:HUB2(display_short)|uniprotkb:BRE1B(gene name synonym)|uniprotkb:Protein HISTONE MONOUBIQUITINATION 2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1-like 2(gene name synonym)|uniprotkb:F7A10.17(orf name)|uniprotkb:At1g55250/At1g55255(locus name)	psi-mi:ubc2_arath(display_long)|uniprotkb:Ubiquitin-protein ligase 2(gene name synonym)|uniprotkb:Ubiquitin carrier protein 2(gene name synonym)|uniprotkb:T20F6.10(orf name)|uniprotkb:At2g02760(locus name)|uniprotkb:UBC2(gene name)|psi-mi:UBC2(display_short)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Cao et al. (2008)	pubmed:18849490|imex:IM-20128	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2012582|imex:IM-20128-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_564680.4|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|refseq:NP_001154428.1|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|ensemblplants:AT1G55250(gene)|ensemblplants:AT1G55250.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0009965"(leaf morphogenesis)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010228"(vegetative to reproductive phase transition of meristem)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)	refseq:NP_565289.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR023313|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|refseq:NP_001325162.1|refseq:NP_001325163.1|refseq:NP_001325164.1|ensemblplants:AT2G02760(gene)|ensemblplants:AT2G02760.1(transcript)|ensemblplants:AT2G02760.2(transcript)|ensemblplants:AT2G02760.3(transcript)|ensemblplants:AT2G02760.4(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010228"(vegetative to reproductive phase transition of meristem)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)	-	-	-	figure legend:Figure 5A|comment:"The authors concluded that the RING finger domain of HUB1 or HUB2 was shown to be necessary for its interactions with UBC1 and UBC2, due to the fact that each interaction was abolished if the RING finger domain was deleted\"."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/10/15	2014/10/16	rogid:GESUJ83OolAEUxbXsnPfEoL3QM83702	rogid:aJy6H/gPHLOvtdG9HioNCnGXNH03702	intact-crc:A780CDA635239B65|rigid:eBhGjoZ7vPTtQNZ4wBvSb5qrjYw	false	necessary binding region:850-900	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9C895	uniprotkb:Q9C895	intact:EBI-2012230|uniprotkb:Q058L1|uniprotkb:Q8LDW7|ensemblplants:AT1G55250.1	intact:EBI-2012230|uniprotkb:Q058L1|uniprotkb:Q8LDW7|ensemblplants:AT1G55250.1	psi-mi:bre1b_arath(display_long)|uniprotkb:HUB2(gene name)|psi-mi:HUB2(display_short)|uniprotkb:BRE1B(gene name synonym)|uniprotkb:Protein HISTONE MONOUBIQUITINATION 2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1-like 2(gene name synonym)|uniprotkb:F7A10.17(orf name)|uniprotkb:At1g55250/At1g55255(locus name)	psi-mi:bre1b_arath(display_long)|uniprotkb:HUB2(gene name)|psi-mi:HUB2(display_short)|uniprotkb:BRE1B(gene name synonym)|uniprotkb:Protein HISTONE MONOUBIQUITINATION 2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1-like 2(gene name synonym)|uniprotkb:F7A10.17(orf name)|uniprotkb:At1g55250/At1g55255(locus name)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Cao et al. (2008)	pubmed:18849490|imex:IM-20128	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2012461|imex:IM-20128-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_564680.4|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|refseq:NP_001154428.1|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|ensemblplants:AT1G55250(gene)|ensemblplants:AT1G55250.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0009965"(leaf morphogenesis)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010228"(vegetative to reproductive phase transition of meristem)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)	refseq:NP_564680.4|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|refseq:NP_001154428.1|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|ensemblplants:AT1G55250(gene)|ensemblplants:AT1G55250.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0009965"(leaf morphogenesis)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010228"(vegetative to reproductive phase transition of meristem)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)	go:"GO:0005634"(nucleus)	-	-	figure legend:Figure 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:3702(arath-mesophyll)|taxid:3702(Arabidopsis thaliana mesophyll)	-	2008/10/15	2014/10/16	rogid:GESUJ83OolAEUxbXsnPfEoL3QM83702	rogid:GESUJ83OolAEUxbXsnPfEoL3QM83702	intact-crc:748D81CD12E34C68|rigid:83TGxin27k4rXHwQOYwJLyLzeLE	false	yellow fluorescent protein tag:?-?	yellow fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q8RXD6	uniprotkb:Q8RXD6	intact:EBI-2012188|uniprotkb:O22156|uniprotkb:O22157|ensemblplants:AT2G44950.1	intact:EBI-2012188|uniprotkb:O22156|uniprotkb:O22157|ensemblplants:AT2G44950.1	psi-mi:bre1a_arath(display_long)|uniprotkb:HUB1(gene name)|psi-mi:HUB1(display_short)|uniprotkb:BRE1A(gene name synonym)|uniprotkb:Protein HISTONE MONOUBIQUITINATION 1(gene name synonym)|uniprotkb:Protein REDUCED DORMANCY 4(gene name synonym)|uniprotkb:RDO4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1-like 1(gene name synonym)|uniprotkb:T13E15.24/T13E15.23(orf name)|uniprotkb:T14P1.25/T14P1.24(orf name)|uniprotkb:At2g44950/At2g44960(locus name)	psi-mi:bre1a_arath(display_long)|uniprotkb:HUB1(gene name)|psi-mi:HUB1(display_short)|uniprotkb:BRE1A(gene name synonym)|uniprotkb:Protein HISTONE MONOUBIQUITINATION 1(gene name synonym)|uniprotkb:Protein REDUCED DORMANCY 4(gene name synonym)|uniprotkb:RDO4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1-like 1(gene name synonym)|uniprotkb:T13E15.24/T13E15.23(orf name)|uniprotkb:T14P1.25/T14P1.24(orf name)|uniprotkb:At2g44950/At2g44960(locus name)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Cao et al. (2008)	pubmed:18849490|imex:IM-20128	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2012474|imex:IM-20128-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_182022.2|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|ensemblplants:AT2G44950(gene)|ensemblplants:AT2G44950.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0009965"(leaf morphogenesis)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010228"(vegetative to reproductive phase transition of meristem)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051301"(cell division)|go:"GO:0051781"(positive regulation of cell division)	refseq:NP_182022.2|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|ensemblplants:AT2G44950(gene)|ensemblplants:AT2G44950.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0009965"(leaf morphogenesis)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010228"(vegetative to reproductive phase transition of meristem)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051301"(cell division)|go:"GO:0051781"(positive regulation of cell division)	go:"GO:0005634"(nucleus)	-	-	figure legend:Figure 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:3702(arath-mesophyll)|taxid:3702(Arabidopsis thaliana mesophyll)	-	2008/10/15	2014/10/16	rogid:n6hz9X+NX9lqeKwVsERMg3FAomw3702	rogid:n6hz9X+NX9lqeKwVsERMg3FAomw3702	intact-crc:F2A95D9231315FC6|rigid:49ijTCm1tLqGKeHwgM2oBIARLy0	false	yellow fluorescent protein tag:?-?	yellow fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q8RXD6	uniprotkb:Q9C895	intact:EBI-2012188|uniprotkb:O22156|uniprotkb:O22157|ensemblplants:AT2G44950.1	intact:EBI-2012230|uniprotkb:Q058L1|uniprotkb:Q8LDW7|ensemblplants:AT1G55250.1	psi-mi:bre1a_arath(display_long)|uniprotkb:HUB1(gene name)|psi-mi:HUB1(display_short)|uniprotkb:BRE1A(gene name synonym)|uniprotkb:Protein HISTONE MONOUBIQUITINATION 1(gene name synonym)|uniprotkb:Protein REDUCED DORMANCY 4(gene name synonym)|uniprotkb:RDO4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1-like 1(gene name synonym)|uniprotkb:T13E15.24/T13E15.23(orf name)|uniprotkb:T14P1.25/T14P1.24(orf name)|uniprotkb:At2g44950/At2g44960(locus name)	psi-mi:bre1b_arath(display_long)|uniprotkb:HUB2(gene name)|psi-mi:HUB2(display_short)|uniprotkb:BRE1B(gene name synonym)|uniprotkb:Protein HISTONE MONOUBIQUITINATION 2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1-like 2(gene name synonym)|uniprotkb:F7A10.17(orf name)|uniprotkb:At1g55250/At1g55255(locus name)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Cao et al. (2008)	pubmed:18849490|imex:IM-20128	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2012486|imex:IM-20128-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_182022.2|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|ensemblplants:AT2G44950(gene)|ensemblplants:AT2G44950.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0009965"(leaf morphogenesis)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010228"(vegetative to reproductive phase transition of meristem)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051301"(cell division)|go:"GO:0051781"(positive regulation of cell division)	refseq:NP_564680.4|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|refseq:NP_001154428.1|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|ensemblplants:AT1G55250(gene)|ensemblplants:AT1G55250.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0009965"(leaf morphogenesis)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010228"(vegetative to reproductive phase transition of meristem)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)	go:"GO:0005634"(nucleus)	-	-	figure legend:Figure 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:3702(arath-mesophyll)|taxid:3702(Arabidopsis thaliana mesophyll)	-	2008/10/15	2014/10/16	rogid:n6hz9X+NX9lqeKwVsERMg3FAomw3702	rogid:GESUJ83OolAEUxbXsnPfEoL3QM83702	intact-crc:D091F3A1831D0F8A|rigid:P8mlcRKcQpk5T3gHt3UX8DOmJJ8	false	yellow fluorescent protein tag:?-?	yellow fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)