#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O00834	uniprotkb:Q9XYH7	intact:EBI-8078093|intact:MINT-6801851	intact:EBI-8078076|intact:MINT-6801833	psi-mi:mic1_toxgo(display_long)|uniprotkb:MIC1(gene name)|psi-mi:MIC1(display_short)	psi-mi:mic6_toxgo(display_long)|uniprotkb:MIC6(gene name)|psi-mi:MIC6(display_short)	psi-mi:"MI:0071"(molecular sieving)	Sawmynaden et al. (2008)	pubmed:18818666|imex:IM-9555|mint:MINT-6801821|doi:10.1038/embor.2008.179	taxid:5811(toxgo)|taxid:5811(Toxoplasma gondii)	taxid:5811(toxgo)|taxid:5811(Toxoplasma gondii)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8078115|mint:MINT-6801871|imex:IM-9555-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038686|interpro:IPR024691|interpro:IPR019562|interpro:IPR008117(MIC1 microneme)|mint:O00834|go:"GO:0007155"(cell adhesion)|go:"GO:0020009"(microneme)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031410"(cytoplasmic vesicle)|rcsb pdb:2BVB|rcsb pdb:2JH1|rcsb pdb:2JH7|rcsb pdb:2JHD|rcsb pdb:2K2S|rcsb pdb:3F53|rcsb pdb:3F5A|rcsb pdb:3F5E|mint:MINT-6801873(identity)	interpro:IPR000742(EGF-like, type 3)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR001881(EGF-like calcium-binding)|mint:Q9XYH7|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007155"(cell adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033163"(microneme membrane)|rcsb pdb:2K2S|rcsb pdb:2K2T|mint:MINT-6801874(identity)	-	function:Adhesin. Required for attachment of the parasite to the host cell prior to invasion. Ensures correct folding of MIC6 and transport of the MIC6-MIC1-MIC4 complex into the micronemes|comment:mint	function:Escorter protein required for import of MIC1 and MIC4 adhesins into the microneme|comment:mint	figure legend:F1B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/27	2014/10/16	rogid:0Znk8eLXQglWhjPpxViKhMliU705811	rogid:ux1BB+QEDha7XCCYwRf2is5Q5v05811	intact-crc:475F831CB273D62C|rigid:15igRSg+r/xOzCX92jHNcU1AlCc	false	binding-associated region:320-456(MINT-6801876)	binding-associated region:99-141(MINT-6801880)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00834	uniprotkb:Q9XYH7	intact:EBI-8078093|intact:MINT-6801851	intact:EBI-8078076|intact:MINT-6801833	psi-mi:mic1_toxgo(display_long)|uniprotkb:MIC1(gene name)|psi-mi:MIC1(display_short)	psi-mi:mic6_toxgo(display_long)|uniprotkb:MIC6(gene name)|psi-mi:MIC6(display_short)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Sawmynaden et al. (2008)	pubmed:18818666|imex:IM-9555|mint:MINT-6801821|doi:10.1038/embor.2008.179	taxid:5811(toxgo)|taxid:5811(Toxoplasma gondii)	taxid:5811(toxgo)|taxid:5811(Toxoplasma gondii)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8078145|mint:MINT-6801885|imex:IM-9555-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038686|interpro:IPR024691|interpro:IPR019562|interpro:IPR008117(MIC1 microneme)|mint:O00834|go:"GO:0007155"(cell adhesion)|go:"GO:0020009"(microneme)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031410"(cytoplasmic vesicle)|rcsb pdb:2BVB|rcsb pdb:2JH1|rcsb pdb:2JH7|rcsb pdb:2JHD|rcsb pdb:2K2S|rcsb pdb:3F53|rcsb pdb:3F5A|rcsb pdb:3F5E|mint:MINT-6801892(identity)	interpro:IPR000742(EGF-like, type 3)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR001881(EGF-like calcium-binding)|mint:Q9XYH7|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007155"(cell adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033163"(microneme membrane)|rcsb pdb:2K2S|rcsb pdb:2K2T|mint:MINT-6801887(identity)	-	function:Adhesin. Required for attachment of the parasite to the host cell prior to invasion. Ensures correct folding of MIC6 and transport of the MIC6-MIC1-MIC4 complex into the micronemes|comment:mint	function:Escorter protein required for import of MIC1 and MIC4 adhesins into the microneme|comment:mint	figure legend:F1C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:5.3x10^-8(molar)	2008/11/27	2014/10/16	rogid:0Znk8eLXQglWhjPpxViKhMliU705811	rogid:ux1BB+QEDha7XCCYwRf2is5Q5v05811	intact-crc:7D6C73BF10E43AF7|rigid:15igRSg+r/xOzCX92jHNcU1AlCc	false	binding-associated region:320-456(MINT-6801893)	binding-associated region:99-141(MINT-6801888)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00834	uniprotkb:Q9XYH7	intact:EBI-8078093|intact:MINT-6801851	intact:EBI-8078076|intact:MINT-6801833	psi-mi:mic1_toxgo(display_long)|uniprotkb:MIC1(gene name)|psi-mi:MIC1(display_short)	psi-mi:mic6_toxgo(display_long)|uniprotkb:MIC6(gene name)|psi-mi:MIC6(display_short)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Sawmynaden et al. (2008)	pubmed:18818666|imex:IM-9555|mint:MINT-6801821|doi:10.1038/embor.2008.179	taxid:5811(toxgo)|taxid:5811(Toxoplasma gondii)	taxid:5811(toxgo)|taxid:5811(Toxoplasma gondii)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8078187|mint:MINT-6801900|imex:IM-9555-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038686|interpro:IPR024691|interpro:IPR019562|interpro:IPR008117(MIC1 microneme)|mint:O00834|go:"GO:0007155"(cell adhesion)|go:"GO:0020009"(microneme)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031410"(cytoplasmic vesicle)|rcsb pdb:2BVB|rcsb pdb:2JH1|rcsb pdb:2JH7|rcsb pdb:2JHD|rcsb pdb:2K2S|rcsb pdb:3F53|rcsb pdb:3F5A|rcsb pdb:3F5E|mint:MINT-6801902(identity)	interpro:IPR000742(EGF-like, type 3)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR001881(EGF-like calcium-binding)|mint:Q9XYH7|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007155"(cell adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033163"(microneme membrane)|rcsb pdb:2K2S|rcsb pdb:2K2T|mint:MINT-6801906(identity)	-	function:Adhesin. Required for attachment of the parasite to the host cell prior to invasion. Ensures correct folding of MIC6 and transport of the MIC6-MIC1-MIC4 complex into the micronemes|comment:mint	function:Escorter protein required for import of MIC1 and MIC4 adhesins into the microneme|comment:mint	figure legend:F2|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/27	2014/10/16	rogid:0Znk8eLXQglWhjPpxViKhMliU705811	rogid:ux1BB+QEDha7XCCYwRf2is5Q5v05811	intact-crc:7D1AAD88CD464648|rigid:15igRSg+r/xOzCX92jHNcU1AlCc	false	binding-associated region:320-456(MINT-6801903)	binding-associated region:87-147(MINT-6801907)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)