#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q12287 uniprotkb:P27882 intact:EBI-5086|uniprotkb:D6VXZ3|ensemblfungi:YLL009C intact:EBI-6621|uniprotkb:D6VUG4|ensemblfungi:YGR029W psi-mi:cox17_yeast(display_long)|uniprotkb:COX17(gene name)|psi-mi:COX17(display_short)|uniprotkb:L1343(orf name)|uniprotkb:YLL009C(locus name) psi-mi:erv1_yeast(display_long)|uniprotkb:Essential for respiration and vegetative growth protein 1(gene name synonym)|uniprotkb:14 kDa regulatory protein(gene name synonym)|uniprotkb:ERV1(gene name)|psi-mi:ERV1(display_short)|uniprotkb:YGR029W(locus name) psi-mi:"MI:0401"(biochemical) Mesecke et al. (2008) pubmed:18787558|imex:IM-9554|mint:MINT-6801867|doi:10.1038/embor.2008.173 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8071399|mint:MINT-6801930|imex:IM-9554-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013092.1|sgd:S000003932|dip:DIP-2915N|mint:Q12287|ensemblfungi:YLL009C(gene)|ensemblfungi:YLL009C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0015680"(protein maturation by copper ion transfer)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0018343"(protein farnesylation)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:1903136"(cuprous ion binding)|interpro:IPR007745(Cytochrome C oxidase copper chaperone)|interpro:IPR009069(MTCP1)|rcsb pdb:1U96|rcsb pdb:1U97|rcsb pdb:1Z2G|mint:MINT-6801935(identity) refseq:NP_011543.4|sgd:S000003261|interpro:IPR017905|interpro:IPR036774|mint:P27882|interpro:IPR039799|ensemblfungi:YGR029W(gene)|ensemblfungi:YGR029W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016971"(flavin-linked sulfhydryl oxidase activity)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0050660"(flavin adenine dinucleotide binding)|rcsb pdb:3W4Y|rcsb pdb:4E0H|rcsb pdb:4E0I|mint:MINT-6801933(identity) go:"GO:0005739"(mitochondrion) - - figure legend:F2A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2008/11/27 2014/10/16 rogid:rekF411Tyc8vZp5Y3l9JynM+QV0559292 rogid:nYYS2xiutIkSeWN8DabWui0hzr4559292 intact-crc:6737764219814B93|rigid:vKH2Q+pVWhsT4sUBPuiDHJ7/01E false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12287 uniprotkb:P08417 intact:EBI-5086|uniprotkb:D6VXZ3|ensemblfungi:YLL009C intact:EBI-7165|uniprotkb:Q08978|uniprotkb:D6W3A8|ensemblfungi:YPL262W psi-mi:cox17_yeast(display_long)|uniprotkb:COX17(gene name)|psi-mi:COX17(display_short)|uniprotkb:L1343(orf name)|uniprotkb:YLL009C(locus name) psi-mi:fumh_yeast(display_long)|uniprotkb:FUM1(gene name)|psi-mi:FUM1(display_short)|uniprotkb:YPL262W(locus name) psi-mi:"MI:0401"(biochemical) Mesecke et al. (2008) pubmed:18787558|imex:IM-9554|mint:MINT-6801867|doi:10.1038/embor.2008.173 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8071399|mint:MINT-6801930|imex:IM-9554-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013092.1|sgd:S000003932|dip:DIP-2915N|mint:Q12287|ensemblfungi:YLL009C(gene)|ensemblfungi:YLL009C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0015680"(protein maturation by copper ion transfer)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0018343"(protein farnesylation)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:1903136"(cuprous ion binding)|interpro:IPR007745(Cytochrome C oxidase copper chaperone)|interpro:IPR009069(MTCP1)|rcsb pdb:1U96|rcsb pdb:1U97|rcsb pdb:1Z2G|mint:MINT-6801935(identity) dip:DIP-6451N|refseq:NP_015061.1|sgd:S000006183|mint:P08417|ensemblfungi:YPL262W(gene)|ensemblfungi:YPL262W_mRNA(transcript)|go:"GO:0004333"(fumarate hydratase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006106"(fumarate metabolic process)|go:"GO:0006108"(malate metabolic process)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0045239"(tricarboxylic acid cycle enzyme complex)|interpro:IPR000362(Fumarate lyase)|interpro:IPR005677(Fumarate hydratase, class II)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR018951|interpro:IPR020557|interpro:IPR022761|interpro:IPR024083|rcsb pdb:1YFM|reactome:R-SCE-71403|mint:MINT-6801937(identity) go:"GO:0005739"(mitochondrion) - crc64:C099A02409A210E6 figure legend:F2A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2008/11/27 2014/10/16 rogid:rekF411Tyc8vZp5Y3l9JynM+QV0559292 rogid:eiUjJxrQgnGgnux7rp9AD7zVMJ0559292 intact-crc:6737764219814B93|rigid:vKH2Q+pVWhsT4sUBPuiDHJ7/01E false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12287 uniprotkb:P36046 intact:EBI-5086|uniprotkb:D6VXZ3|ensemblfungi:YLL009C intact:EBI-26978|uniprotkb:D6VX05|ensemblfungi:YKL195W psi-mi:cox17_yeast(display_long)|uniprotkb:COX17(gene name)|psi-mi:COX17(display_short)|uniprotkb:L1343(orf name)|uniprotkb:YLL009C(locus name) psi-mi:mia40_yeast(display_long)|uniprotkb:YKL195W(locus name)|uniprotkb:MIA40(gene name)|psi-mi:MIA40(display_short)|uniprotkb:TIM40(gene name synonym)|uniprotkb:Mitochondrial import inner membrane translocase TIM40(gene name synonym) psi-mi:"MI:0401"(biochemical) Mesecke et al. (2008) pubmed:18787558|imex:IM-9554|mint:MINT-6801867|doi:10.1038/embor.2008.173 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8071399|mint:MINT-6801930|imex:IM-9554-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013092.1|sgd:S000003932|dip:DIP-2915N|mint:Q12287|ensemblfungi:YLL009C(gene)|ensemblfungi:YLL009C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0015680"(protein maturation by copper ion transfer)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0018343"(protein farnesylation)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:1903136"(cuprous ion binding)|interpro:IPR007745(Cytochrome C oxidase copper chaperone)|interpro:IPR009069(MTCP1)|rcsb pdb:1U96|rcsb pdb:1U97|rcsb pdb:1Z2G|mint:MINT-6801935(identity) refseq:NP_012726.2|sgd:S000001678|mint:P36046|dip:DIP-5432N|ensemblfungi:YKL195W(gene)|ensemblfungi:YKL195W_mRNA(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR010625(CHCH)|interpro:IPR039289|rcsb pdb:2ZXT|rcsb pdb:3A3C|mint:MINT-6801932(identity) go:"GO:0005739"(mitochondrion) - crc64:5904E8D0213D6EFA figure legend:F2A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2008/11/27 2014/10/16 rogid:rekF411Tyc8vZp5Y3l9JynM+QV0559292 rogid:h/qutsTcZkAqeNJAcTyWJ3FfTrQ559292 intact-crc:6737764219814B93|rigid:vKH2Q+pVWhsT4sUBPuiDHJ7/01E false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12287 uniprotkb:P00445 intact:EBI-5086|uniprotkb:D6VXZ3|ensemblfungi:YLL009C intact:EBI-17635|ensemblfungi:YJR104C|uniprotkb:Q68HB2|uniprotkb:D6VWS3 psi-mi:cox17_yeast(display_long)|uniprotkb:COX17(gene name)|psi-mi:COX17(display_short)|uniprotkb:L1343(orf name)|uniprotkb:YLL009C(locus name) psi-mi:sodc_yeast(display_long)|uniprotkb:SOD1(gene name)|psi-mi:SOD1(display_short)|uniprotkb:J1968(orf name)|uniprotkb:YJR104C(locus name) psi-mi:"MI:0401"(biochemical) Mesecke et al. (2008) pubmed:18787558|imex:IM-9554|mint:MINT-6801867|doi:10.1038/embor.2008.173 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8071399|mint:MINT-6801930|imex:IM-9554-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013092.1|sgd:S000003932|dip:DIP-2915N|mint:Q12287|ensemblfungi:YLL009C(gene)|ensemblfungi:YLL009C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0015680"(protein maturation by copper ion transfer)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0018343"(protein farnesylation)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:1903136"(cuprous ion binding)|interpro:IPR007745(Cytochrome C oxidase copper chaperone)|interpro:IPR009069(MTCP1)|rcsb pdb:1U96|rcsb pdb:1U97|rcsb pdb:1Z2G|mint:MINT-6801935(identity) rcsb pdb:2JCW|reactome:R-SCE-114608|reactome:R-SCE-3299685|rcsb pdb:1YSO|ensemblfungi:YJR104C(gene)|ensemblfungi:YJR104C_mRNA(transcript)|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:1901856"(negative regulation of cellular respiration)|interpro:IPR001424(Superoxide dismutase, copper/zinc binding)|interpro:IPR018152|interpro:IPR024134|interpro:IPR036423|rcsb pdb:1B4L|rcsb pdb:1B4T|rcsb pdb:1F18|rcsb pdb:1F1A|rcsb pdb:1F1D|rcsb pdb:1F1G|rcsb pdb:1JCV|rcsb pdb:1JK9|rcsb pdb:1SDY|rcsb pdb:1YAZ|refseq:NP_012638.1|sgd:S000003865|dip:DIP-5859N|mint:P00445|mint:MINT-6801936(identity) go:"GO:0005739"(mitochondrion) - crc64:E263A74679AF11F7 figure legend:F2A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2008/11/27 2014/10/16 rogid:rekF411Tyc8vZp5Y3l9JynM+QV0559292 rogid:VeBiiZSl4AcfLVnsgVUOZ7vqf1g559292 intact-crc:6737764219814B93|rigid:vKH2Q+pVWhsT4sUBPuiDHJ7/01E false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12287 uniprotkb:P53299 intact:EBI-5086|uniprotkb:D6VXZ3|ensemblfungi:YLL009C intact:EBI-9121|ensemblfungi:YGR181W|uniprotkb:D6VUW5 psi-mi:cox17_yeast(display_long)|uniprotkb:COX17(gene name)|psi-mi:COX17(display_short)|uniprotkb:L1343(orf name)|uniprotkb:YLL009C(locus name) psi-mi:tim13_yeast(display_long)|uniprotkb:G7157(orf name)|uniprotkb:YGR181W(locus name)|uniprotkb:TIM13(gene name)|psi-mi:TIM13(display_short) psi-mi:"MI:0401"(biochemical) Mesecke et al. (2008) pubmed:18787558|imex:IM-9554|mint:MINT-6801867|doi:10.1038/embor.2008.173 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8071399|mint:MINT-6801930|imex:IM-9554-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013092.1|sgd:S000003932|dip:DIP-2915N|mint:Q12287|ensemblfungi:YLL009C(gene)|ensemblfungi:YLL009C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0015680"(protein maturation by copper ion transfer)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0018343"(protein farnesylation)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:1903136"(cuprous ion binding)|interpro:IPR007745(Cytochrome C oxidase copper chaperone)|interpro:IPR009069(MTCP1)|rcsb pdb:1U96|rcsb pdb:1U97|rcsb pdb:1Z2G|mint:MINT-6801935(identity) ensemblfungi:YGR181W(gene)|ensemblfungi:YGR181W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0140318"(protein transporter activity)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|rcsb pdb:3CJH|refseq:NP_011697.3|sgd:S000003413|dip:DIP-5547N|mint:P53299|mint:MINT-6801934(identity) go:"GO:0005739"(mitochondrion) - - figure legend:F2A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2008/11/27 2014/10/16 rogid:rekF411Tyc8vZp5Y3l9JynM+QV0559292 rogid:VkM3K4RclcQUZwNCm3bPPlyY99Y559292 intact-crc:6737764219814B93|rigid:vKH2Q+pVWhsT4sUBPuiDHJ7/01E false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P27882 uniprotkb:P36078 intact:EBI-6621|uniprotkb:D6VUG4|ensemblfungi:YGR029W intact:EBI-26770|uniprotkb:Q6Q598|uniprotkb:D6VXK4|ensemblfungi:YKL084W psi-mi:erv1_yeast(display_long)|uniprotkb:Essential for respiration and vegetative growth protein 1(gene name synonym)|uniprotkb:14 kDa regulatory protein(gene name synonym)|uniprotkb:ERV1(gene name)|psi-mi:ERV1(display_short)|uniprotkb:YGR029W(locus name) psi-mi:hot13_yeast(display_long)|uniprotkb:YKL084W(locus name)|uniprotkb:HOT13(gene name)|psi-mi:HOT13(display_short) psi-mi:"MI:0096"(pull down) Mesecke et al. (2008) pubmed:18787558|imex:IM-9554|mint:MINT-6801867|doi:10.1038/embor.2008.173 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8071452|mint:MINT-6801956|imex:IM-9554-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011543.4|sgd:S000003261|interpro:IPR017905|interpro:IPR036774|mint:P27882|interpro:IPR039799|ensemblfungi:YGR029W(gene)|ensemblfungi:YGR029W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016971"(flavin-linked sulfhydryl oxidase activity)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0050660"(flavin adenine dinucleotide binding)|rcsb pdb:3W4Y|rcsb pdb:4E0H|rcsb pdb:4E0I|mint:MINT-6801958(identity) refseq:NP_012839.1|sgd:S000001567|interpro:IPR016694(Uncharacterised conserved protein UCP017292, zinc finger, CHY-type)|interpro:IPR008913(Zinc finger, CHY-type)|interpro:IPR037274|mint:P36078|ensemblfungi:YKL084W(gene)|ensemblfungi:YKL084W_mRNA(transcript)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|mint:MINT-6801959(identity) - - - figure legend:F3A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2008/11/27 2014/10/16 rogid:nYYS2xiutIkSeWN8DabWui0hzr4559292 rogid:IexYl9dzFVsqYLmZfR4y3OBjmeI559292 intact-crc:0FD4025E7B568775|rigid:wiZDkdKVmelvg80qZG312i5JJEM false - his tag:?-?(MINT-6801961) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27882 uniprotkb:P36046 intact:EBI-6621|uniprotkb:D6VUG4|ensemblfungi:YGR029W intact:EBI-26978|uniprotkb:D6VX05|ensemblfungi:YKL195W psi-mi:erv1_yeast(display_long)|uniprotkb:Essential for respiration and vegetative growth protein 1(gene name synonym)|uniprotkb:14 kDa regulatory protein(gene name synonym)|uniprotkb:ERV1(gene name)|psi-mi:ERV1(display_short)|uniprotkb:YGR029W(locus name) psi-mi:mia40_yeast(display_long)|uniprotkb:YKL195W(locus name)|uniprotkb:MIA40(gene name)|psi-mi:MIA40(display_short)|uniprotkb:TIM40(gene name synonym)|uniprotkb:Mitochondrial import inner membrane translocase TIM40(gene name synonym) psi-mi:"MI:0096"(pull down) Mesecke et al. (2008) pubmed:18787558|imex:IM-9554|mint:MINT-6801867|doi:10.1038/embor.2008.173 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8071466|mint:MINT-6801967|imex:IM-9554-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011543.4|sgd:S000003261|interpro:IPR017905|interpro:IPR036774|mint:P27882|interpro:IPR039799|ensemblfungi:YGR029W(gene)|ensemblfungi:YGR029W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016971"(flavin-linked sulfhydryl oxidase activity)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0050660"(flavin adenine dinucleotide binding)|rcsb pdb:3W4Y|rcsb pdb:4E0H|rcsb pdb:4E0I|mint:MINT-6801973(identity) refseq:NP_012726.2|sgd:S000001678|mint:P36046|dip:DIP-5432N|ensemblfungi:YKL195W(gene)|ensemblfungi:YKL195W_mRNA(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR010625(CHCH)|interpro:IPR039289|rcsb pdb:2ZXT|rcsb pdb:3A3C|mint:MINT-6801969(identity) - - crc64:5904E8D0213D6EFA figure legend:F3A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2008/11/27 2014/10/16 rogid:nYYS2xiutIkSeWN8DabWui0hzr4559292 rogid:h/qutsTcZkAqeNJAcTyWJ3FfTrQ559292 intact-crc:789B880C7BC7159F|rigid:aEpj4HyMxUOPZkmpzpjAEyuWN+c false his tag:?-?(MINT-6801976) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:P27882 uniprotkb:P36046 intact:EBI-6621|uniprotkb:D6VUG4|ensemblfungi:YGR029W intact:EBI-26978|uniprotkb:D6VX05|ensemblfungi:YKL195W psi-mi:erv1_yeast(display_long)|uniprotkb:Essential for respiration and vegetative growth protein 1(gene name synonym)|uniprotkb:14 kDa regulatory protein(gene name synonym)|uniprotkb:ERV1(gene name)|psi-mi:ERV1(display_short)|uniprotkb:YGR029W(locus name) psi-mi:mia40_yeast(display_long)|uniprotkb:YKL195W(locus name)|uniprotkb:MIA40(gene name)|psi-mi:MIA40(display_short)|uniprotkb:TIM40(gene name synonym)|uniprotkb:Mitochondrial import inner membrane translocase TIM40(gene name synonym) psi-mi:"MI:0415"(enzymatic study) Mesecke et al. (2008) pubmed:18787558|imex:IM-9554|mint:MINT-6801867|doi:10.1038/embor.2008.173 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8071491|mint:MINT-6801983|imex:IM-9554-3 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011543.4|sgd:S000003261|interpro:IPR017905|interpro:IPR036774|mint:P27882|interpro:IPR039799|ensemblfungi:YGR029W(gene)|ensemblfungi:YGR029W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016971"(flavin-linked sulfhydryl oxidase activity)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0050660"(flavin adenine dinucleotide binding)|rcsb pdb:3W4Y|rcsb pdb:4E0H|rcsb pdb:4E0I|mint:MINT-6801987(identity) refseq:NP_012726.2|sgd:S000001678|mint:P36046|dip:DIP-5432N|ensemblfungi:YKL195W(gene)|ensemblfungi:YKL195W_mRNA(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR010625(CHCH)|interpro:IPR039289|rcsb pdb:2ZXT|rcsb pdb:3A3C|mint:MINT-6801985(identity) - - crc64:5904E8D0213D6EFA figure legend:F4A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/11/27 2014/10/16 rogid:nYYS2xiutIkSeWN8DabWui0hzr4559292 rogid:h/qutsTcZkAqeNJAcTyWJ3FfTrQ559292 intact-crc:8B77B7027399BAA0|rigid:aEpj4HyMxUOPZkmpzpjAEyuWN+c false - binding-associated region:284-403(MINT-6801995) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)