#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q7TPH6	uniprotkb:Q63633	intact:EBI-1811542|uniprotkb:Q6PCM8|uniprotkb:E9PUJ6	intact:EBI-1811510|uniprotkb:A7Y821	psi-mi:mycb2_mouse(display_long)|uniprotkb:Mycbp2(gene name)|psi-mi:Mycbp2(display_short)|uniprotkb:Pam(gene name synonym)|uniprotkb:Phr1(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym)|uniprotkb:Pam/highwire/rpm-1 protein(gene name synonym)|uniprotkb:Protein Magellan(gene name synonym)	psi-mi:s12a5_rat(display_long)|uniprotkb:Slc12a5(gene name)|psi-mi:Slc12a5(display_short)|uniprotkb:Kcc2(gene name synonym)|uniprotkb:Electroneutral potassium-chloride cotransporter 2(gene name synonym)|uniprotkb:K-Cl cotransporter 2(gene name synonym)|uniprotkb:Neuronal K-Cl cotransporter(gene name synonym)|uniprotkb:Furosemide-sensitive K-Cl cotransporter(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Garbarini et al. (2008)	pubmed:18769030|imex:IM-19157	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1811538|imex:IM-19157-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR008979(Galactose-binding like)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR012983(PHR)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR001841(Zinc finger, RING-type)|refseq:NP_997098.2|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR017868|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q7TPH6|interpro:IPR038648|interpro:IPR003646(Bacterial SH3-like region)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030424"(axon)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902667"(regulation of axon guidance)|rcsb pdb:3GBW|rcsb pdb:3HWJ	interpro:IPR004842(Na-K-Cl cotransporter superfamily)|rgd:620811|refseq:NP_599190.1|interpro:IPR004841(Amino acid permease-associated region)|interpro:IPR000076(K-Cl co-transporter)|interpro:IPR030358|mint:Q63633|interpro:IPR018491|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006821"(chloride transport)|go:"GO:0006873"(cellular ion homeostasis)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006971"(hypotonic response)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015379"("potassium:chloride symporter activity")|go:"GO:0015696"|go:"GO:0016021"(integral component of membrane)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032590"(dendrite membrane)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0045202"(synapse)|go:"GO:0051452"(intracellular pH reduction)|go:"GO:0055064"(chloride ion homeostasis)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0060996"(dendritic spine development)|go:"GO:0071944"(cell periphery)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|reactome:R-RNO-426117	-	-	-	figure legend:no figure|caution:Q63633 remapped to parent entry as region of protein used in the 2 hybrid screen is not isoform specific.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/09/15	2018/07/05	rogid:LHdZ193Nhz4e+Iq5+Sua2QwrAWA10090	rogid:re2eaKJoJFpp2Gk1MowLaTa+NYU10116	intact-crc:C97121A649FC3781|rigid:tHU7mRGBSzHUOX5Bg/oMHMm9o6M	false	binding-associated region:589-912	binding-associated region:658-1139	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7TPH6	uniprotkb:Q63633	intact:EBI-1811542|uniprotkb:Q6PCM8|uniprotkb:E9PUJ6	intact:EBI-1811510|uniprotkb:A7Y821	psi-mi:mycb2_mouse(display_long)|uniprotkb:Mycbp2(gene name)|psi-mi:Mycbp2(display_short)|uniprotkb:Pam(gene name synonym)|uniprotkb:Phr1(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym)|uniprotkb:Pam/highwire/rpm-1 protein(gene name synonym)|uniprotkb:Protein Magellan(gene name synonym)	psi-mi:s12a5_rat(display_long)|uniprotkb:Slc12a5(gene name)|psi-mi:Slc12a5(display_short)|uniprotkb:Kcc2(gene name synonym)|uniprotkb:Electroneutral potassium-chloride cotransporter 2(gene name synonym)|uniprotkb:K-Cl cotransporter 2(gene name synonym)|uniprotkb:Neuronal K-Cl cotransporter(gene name synonym)|uniprotkb:Furosemide-sensitive K-Cl cotransporter(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Garbarini et al. (2008)	pubmed:18769030|imex:IM-19157	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1811600|imex:IM-19157-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR008979(Galactose-binding like)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR012983(PHR)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR001841(Zinc finger, RING-type)|refseq:NP_997098.2|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR017868|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q7TPH6|interpro:IPR038648|interpro:IPR003646(Bacterial SH3-like region)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030424"(axon)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902667"(regulation of axon guidance)|rcsb pdb:3GBW|rcsb pdb:3HWJ	interpro:IPR004842(Na-K-Cl cotransporter superfamily)|rgd:620811|refseq:NP_599190.1|interpro:IPR004841(Amino acid permease-associated region)|interpro:IPR000076(K-Cl co-transporter)|interpro:IPR030358|mint:Q63633|interpro:IPR018491|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006821"(chloride transport)|go:"GO:0006873"(cellular ion homeostasis)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006971"(hypotonic response)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015379"("potassium:chloride symporter activity")|go:"GO:0015696"|go:"GO:0016021"(integral component of membrane)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032590"(dendrite membrane)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0045202"(synapse)|go:"GO:0051452"(intracellular pH reduction)|go:"GO:0055064"(chloride ion homeostasis)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0060996"(dendritic spine development)|go:"GO:0071944"(cell periphery)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|reactome:R-RNO-426117	-	-	-	figure legend:5 and 6B|comment:"Carboxyterminal Slc12a5/KCC2 construct (aa 1092-1139) with the mutation tyr1110ala also interacts."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/09/15	2018/07/05	rogid:LHdZ193Nhz4e+Iq5+Sua2QwrAWA10090	rogid:re2eaKJoJFpp2Gk1MowLaTa+NYU10116	intact-crc:D853F0AE9C4DE4C5|rigid:tHU7mRGBSzHUOX5Bg/oMHMm9o6M	false	binding-associated region:589-912	binding-associated region:1092-1112|mutation disrupting interaction:1104-1104|mutation disrupting interaction:1105-1105	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q63633	uniprotkb:Q7TPH6	intact:EBI-1811510|uniprotkb:A7Y821	intact:EBI-1811542|uniprotkb:Q6PCM8|uniprotkb:E9PUJ6	psi-mi:s12a5_rat(display_long)|uniprotkb:Slc12a5(gene name)|psi-mi:Slc12a5(display_short)|uniprotkb:Kcc2(gene name synonym)|uniprotkb:Electroneutral potassium-chloride cotransporter 2(gene name synonym)|uniprotkb:K-Cl cotransporter 2(gene name synonym)|uniprotkb:Neuronal K-Cl cotransporter(gene name synonym)|uniprotkb:Furosemide-sensitive K-Cl cotransporter(gene name synonym)	psi-mi:mycb2_mouse(display_long)|uniprotkb:Mycbp2(gene name)|psi-mi:Mycbp2(display_short)|uniprotkb:Pam(gene name synonym)|uniprotkb:Phr1(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym)|uniprotkb:Pam/highwire/rpm-1 protein(gene name synonym)|uniprotkb:Protein Magellan(gene name synonym)	psi-mi:"MI:0096"(pull down)	Garbarini et al. (2008)	pubmed:18769030|imex:IM-19157	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1811630|imex:IM-19157-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004842(Na-K-Cl cotransporter superfamily)|rgd:620811|refseq:NP_599190.1|interpro:IPR004841(Amino acid permease-associated region)|interpro:IPR000076(K-Cl co-transporter)|interpro:IPR030358|mint:Q63633|interpro:IPR018491|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006821"(chloride transport)|go:"GO:0006873"(cellular ion homeostasis)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006971"(hypotonic response)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015379"("potassium:chloride symporter activity")|go:"GO:0015696"|go:"GO:0016021"(integral component of membrane)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032590"(dendrite membrane)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0045202"(synapse)|go:"GO:0051452"(intracellular pH reduction)|go:"GO:0055064"(chloride ion homeostasis)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0060996"(dendritic spine development)|go:"GO:0071944"(cell periphery)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|reactome:R-RNO-426117	interpro:IPR008979(Galactose-binding like)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR012983(PHR)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR001841(Zinc finger, RING-type)|refseq:NP_997098.2|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR017868|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q7TPH6|interpro:IPR038648|interpro:IPR003646(Bacterial SH3-like region)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030424"(axon)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902667"(regulation of axon guidance)|rcsb pdb:3GBW|rcsb pdb:3HWJ	-	-	-	figure legend:1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/09/15	2018/07/05	rogid:re2eaKJoJFpp2Gk1MowLaTa+NYU10116	rogid:LHdZ193Nhz4e+Iq5+Sua2QwrAWA10090	intact-crc:0B382ED2E1287CA3|rigid:tHU7mRGBSzHUOX5Bg/oMHMm9o6M	false	glutathione s tranferase tag:?-?|binding-associated region:658-1139	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q7TPH6	uniprotkb:Q63633	intact:EBI-1811542|uniprotkb:Q6PCM8|uniprotkb:E9PUJ6	intact:EBI-1811510|uniprotkb:A7Y821	psi-mi:mycb2_mouse(display_long)|uniprotkb:Mycbp2(gene name)|psi-mi:Mycbp2(display_short)|uniprotkb:Pam(gene name synonym)|uniprotkb:Phr1(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym)|uniprotkb:Pam/highwire/rpm-1 protein(gene name synonym)|uniprotkb:Protein Magellan(gene name synonym)	psi-mi:s12a5_rat(display_long)|uniprotkb:Slc12a5(gene name)|psi-mi:Slc12a5(display_short)|uniprotkb:Kcc2(gene name synonym)|uniprotkb:Electroneutral potassium-chloride cotransporter 2(gene name synonym)|uniprotkb:K-Cl cotransporter 2(gene name synonym)|uniprotkb:Neuronal K-Cl cotransporter(gene name synonym)|uniprotkb:Furosemide-sensitive K-Cl cotransporter(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Garbarini et al. (2008)	pubmed:18769030|imex:IM-19157	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1811643|imex:IM-19157-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR008979(Galactose-binding like)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR012983(PHR)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR001841(Zinc finger, RING-type)|refseq:NP_997098.2|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR017868|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q7TPH6|interpro:IPR038648|interpro:IPR003646(Bacterial SH3-like region)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030424"(axon)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902667"(regulation of axon guidance)|rcsb pdb:3GBW|rcsb pdb:3HWJ	interpro:IPR004842(Na-K-Cl cotransporter superfamily)|rgd:620811|refseq:NP_599190.1|interpro:IPR004841(Amino acid permease-associated region)|interpro:IPR000076(K-Cl co-transporter)|interpro:IPR030358|mint:Q63633|interpro:IPR018491|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006821"(chloride transport)|go:"GO:0006873"(cellular ion homeostasis)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006971"(hypotonic response)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015379"("potassium:chloride symporter activity")|go:"GO:0015696"|go:"GO:0016021"(integral component of membrane)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032590"(dendrite membrane)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0045202"(synapse)|go:"GO:0051452"(intracellular pH reduction)|go:"GO:0055064"(chloride ion homeostasis)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0060996"(dendritic spine development)|go:"GO:0071944"(cell periphery)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|reactome:R-RNO-426117	-	-	-	figure legend:1D and 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/09/15	2018/07/05	rogid:LHdZ193Nhz4e+Iq5+Sua2QwrAWA10090	rogid:re2eaKJoJFpp2Gk1MowLaTa+NYU10116	intact-crc:FF49FDA5145FB43C|rigid:tHU7mRGBSzHUOX5Bg/oMHMm9o6M	false	ha tag:?-?|binding-associated region:589-912	mutation decreasing interaction:1104-1104	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)