#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q01590 uniprotkb:Q12154 intact:EBI-16930|uniprotkb:D6VY28|ensemblfungi:YLR026C intact:EBI-2989|uniprotkb:Q6B1B6|uniprotkb:D6VRQ0|ensemblfungi:YDL100C psi-mi:sed5_yeast(display_long)|uniprotkb:SED5(gene name)|psi-mi:SED5(display_short)|uniprotkb:YLR026C(locus name) psi-mi:get3_yeast(display_long)|uniprotkb:YDL100C(locus name)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARR4(gene name synonym)|uniprotkb:D2371(orf name)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins 3(gene name synonym)|uniprotkb:Golgi to ER traffic protein 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Schuldiner et al. (2008) imex:IM-11989|pubmed:18724936 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1955838|imex:IM-11989-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013126.1|sgd:S000004016|ensemblfungi:YLR026C(gene)|ensemblfungi:YLR026C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0090083"(regulation of inclusion body assembly)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR021538|rcsb pdb:1MQS|rcsb pdb:1PD0|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-6807878|reactome:R-SCE-6811438|reactome:R-SCE-9609523|go:"GO:0031201"(SNARE complex)|go:"GO:0048278"(vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|dip:DIP-2489N|mint:Q01590 refseq:NP_010183.1|sgd:S000002258|dip:DIP-3908N|mint:Q12154|ensemblfungi:YDL100C(gene)|ensemblfungi:YDL100C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009408"(response to heat)|go:"GO:0010038"(response to metal ion)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990507"(obsolete ATP-independent chaperone mediated protein folding)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|rcsb pdb:2WOJ|rcsb pdb:3A36|rcsb pdb:3A37|rcsb pdb:3B2E|rcsb pdb:3H84|rcsb pdb:3IDQ|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3SJD|rcsb pdb:3VLC|rcsb pdb:3ZS8|rcsb pdb:3ZS9|rcsb pdb:4PWX|rcsb pdb:4XTR|rcsb pdb:4XVU|rcsb pdb:4XWO|rcsb pdb:5BW8|rcsb pdb:5BWK psi-mi:"MI:0469"(intact) crc64:B3192B57269A0B83 crc64:F795C359B5A4A461 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/09/17 2014/10/16 rogid:c+W+86qfjxcvWWJ9nMScyH5TjNA559292 rogid:Y+PTDg+beVeCH5mn4BvWi5wBP4A559292 intact-crc:D57D612EB5BE80A4|rigid:GaK2AoeIf94Y4oPCx4kdr4Sty40 false sufficient binding region:197-340 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q01590 uniprotkb:Q12154 intact:EBI-16930|uniprotkb:D6VY28|ensemblfungi:YLR026C intact:EBI-2989|uniprotkb:Q6B1B6|uniprotkb:D6VRQ0|ensemblfungi:YDL100C psi-mi:sed5_yeast(display_long)|uniprotkb:SED5(gene name)|psi-mi:SED5(display_short)|uniprotkb:YLR026C(locus name) psi-mi:get3_yeast(display_long)|uniprotkb:YDL100C(locus name)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARR4(gene name synonym)|uniprotkb:D2371(orf name)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins 3(gene name synonym)|uniprotkb:Golgi to ER traffic protein 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Schuldiner et al. (2008) imex:IM-11989|pubmed:18724936 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1955863|imex:IM-11989-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013126.1|sgd:S000004016|ensemblfungi:YLR026C(gene)|ensemblfungi:YLR026C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0090083"(regulation of inclusion body assembly)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR021538|rcsb pdb:1MQS|rcsb pdb:1PD0|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-6807878|reactome:R-SCE-6811438|reactome:R-SCE-9609523|go:"GO:0031201"(SNARE complex)|go:"GO:0048278"(vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|dip:DIP-2489N|mint:Q01590 refseq:NP_010183.1|sgd:S000002258|dip:DIP-3908N|mint:Q12154|ensemblfungi:YDL100C(gene)|ensemblfungi:YDL100C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009408"(response to heat)|go:"GO:0010038"(response to metal ion)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990507"(obsolete ATP-independent chaperone mediated protein folding)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|rcsb pdb:2WOJ|rcsb pdb:3A36|rcsb pdb:3A37|rcsb pdb:3B2E|rcsb pdb:3H84|rcsb pdb:3IDQ|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3SJD|rcsb pdb:3VLC|rcsb pdb:3ZS8|rcsb pdb:3ZS9|rcsb pdb:4PWX|rcsb pdb:4XTR|rcsb pdb:4XVU|rcsb pdb:4XWO|rcsb pdb:5BW8|rcsb pdb:5BWK psi-mi:"MI:0469"(intact) crc64:B3192B57269A0B83 crc64:F795C359B5A4A461 figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/09/17 2014/10/16 rogid:c+W+86qfjxcvWWJ9nMScyH5TjNA559292 rogid:Y+PTDg+beVeCH5mn4BvWi5wBP4A559292 intact-crc:619FDD4A97FCB869|rigid:GaK2AoeIf94Y4oPCx4kdr4Sty40 false necessary binding region:320-340 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08215 uniprotkb:Q12154 intact:EBI-31849|uniprotkb:D6W222|ensemblfungi:YOL044W intact:EBI-2989|uniprotkb:Q6B1B6|uniprotkb:D6VRQ0|ensemblfungi:YDL100C psi-mi:pex15_yeast(display_long)|uniprotkb:Peroxisome biosynthesis protein PAS21(gene name synonym)|uniprotkb:PEX15(gene name)|psi-mi:PEX15(display_short)|uniprotkb:Peroxin-15(gene name synonym)|uniprotkb:PAS21(gene name synonym)|uniprotkb:YOL044W(locus name) psi-mi:get3_yeast(display_long)|uniprotkb:YDL100C(locus name)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARR4(gene name synonym)|uniprotkb:D2371(orf name)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins 3(gene name synonym)|uniprotkb:Golgi to ER traffic protein 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Schuldiner et al. (2008) imex:IM-11989|pubmed:18724936 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1955940|imex:IM-11989-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005404|refseq:NP_014598.1|dip:DIP-4159N|mint:Q08215|ensemblfungi:YOL044W(gene)|ensemblfungi:YOL044W_mRNA(transcript)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016562"(protein import into peroxisome matrix, receptor recycling)|go:"GO:0043495"(protein-membrane adaptor activity)|rcsb pdb:5VXV refseq:NP_010183.1|sgd:S000002258|dip:DIP-3908N|mint:Q12154|ensemblfungi:YDL100C(gene)|ensemblfungi:YDL100C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009408"(response to heat)|go:"GO:0010038"(response to metal ion)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990507"(obsolete ATP-independent chaperone mediated protein folding)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|rcsb pdb:2WOJ|rcsb pdb:3A36|rcsb pdb:3A37|rcsb pdb:3B2E|rcsb pdb:3H84|rcsb pdb:3IDQ|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3SJD|rcsb pdb:3VLC|rcsb pdb:3ZS8|rcsb pdb:3ZS9|rcsb pdb:4PWX|rcsb pdb:4XTR|rcsb pdb:4XVU|rcsb pdb:4XWO|rcsb pdb:5BW8|rcsb pdb:5BWK psi-mi:"MI:0469"(intact) crc64:B575A8D4B0DAC0B8 crc64:F795C359B5A4A461 figure legend:Fig. 3A|comment:The coordinates of the transmembrane domain were not given in the paper and instead have been taken from the UniProt entry.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/09/17 2014/10/16 rogid:nNm7nOvPnFTR9KqeIR3fiw7oqeg559292 rogid:Y+PTDg+beVeCH5mn4BvWi5wBP4A559292 intact-crc:1CBA9CCAD7CCCA84|rigid:nx/k3gfhbX2Qkjr+r+9la9EXTpI false necessary binding region:332..332-349..349 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12154 uniprotkb:P22214 intact:EBI-2989|uniprotkb:Q6B1B6|uniprotkb:D6VRQ0|ensemblfungi:YDL100C intact:EBI-16577|ensemblfungi:YLR268W|uniprotkb:D6VYR6 psi-mi:get3_yeast(display_long)|uniprotkb:YDL100C(locus name)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARR4(gene name synonym)|uniprotkb:D2371(orf name)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins 3(gene name synonym)|uniprotkb:Golgi to ER traffic protein 3(gene name synonym) psi-mi:sec22_yeast(display_long)|uniprotkb:SEC22(gene name)|psi-mi:SEC22(display_short)|uniprotkb:SLY2(gene name synonym)|uniprotkb:YLR268W(locus name)|uniprotkb:L8479.3(orf name)|uniprotkb:TSL26(gene name synonym)|uniprotkb:Suppressor of loss of YPT1 protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Schuldiner et al. (2008) imex:IM-11989|pubmed:18724936 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1955948|imex:IM-11989-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010183.1|sgd:S000002258|dip:DIP-3908N|mint:Q12154|ensemblfungi:YDL100C(gene)|ensemblfungi:YDL100C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009408"(response to heat)|go:"GO:0010038"(response to metal ion)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990507"(obsolete ATP-independent chaperone mediated protein folding)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|rcsb pdb:2WOJ|rcsb pdb:3A36|rcsb pdb:3A37|rcsb pdb:3B2E|rcsb pdb:3H84|rcsb pdb:3IDQ|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3SJD|rcsb pdb:3VLC|rcsb pdb:3ZS8|rcsb pdb:3ZS9|rcsb pdb:4PWX|rcsb pdb:4XTR|rcsb pdb:4XVU|rcsb pdb:4XWO|rcsb pdb:5BW8|rcsb pdb:5BWK refseq:NP_013370.1|sgd:S000004258|ensemblfungi:YLR268W(gene)|ensemblfungi:YLR268W_mRNA(transcript)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0048279"(vesicle fusion with endoplasmic reticulum)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR001388(Synaptobrevin)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR042855|interpro:IPR044565|go:"GO:0000139"(Golgi membrane)|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-6811434|dip:DIP-2234N psi-mi:"MI:0469"(intact) crc64:F795C359B5A4A461 crc64:9FA3E34EAAFB9536 figure legend:Fig. 3A|comment:The coordinates of the transmembrane domain were not given in the paper and instead have been taken from the UniProt entry.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/09/17 2014/10/16 rogid:Y+PTDg+beVeCH5mn4BvWi5wBP4A559292 rogid:TjDU0GL+v84S+TwvRpJmF9CqhZ4559292 intact-crc:5BF2CBCBEB5B8178|rigid:3yxprKMj/RR9uIH+rpgZ34iWqBI false - necessary binding region:193..193-213..213 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08144 uniprotkb:Q12154 intact:EBI-19302|uniprotkb:D6W248|uniprotkb:E9P933|ensemblfungi:YOL018C intact:EBI-2989|uniprotkb:Q6B1B6|uniprotkb:D6VRQ0|ensemblfungi:YDL100C psi-mi:tlg2_yeast(display_long)|uniprotkb:YOL018C(locus name)|uniprotkb:TLG2(gene name)|psi-mi:TLG2(display_short)|uniprotkb:Syntaxin TLG2(gene name synonym) psi-mi:get3_yeast(display_long)|uniprotkb:YDL100C(locus name)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARR4(gene name synonym)|uniprotkb:D2371(orf name)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins 3(gene name synonym)|uniprotkb:Golgi to ER traffic protein 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Schuldiner et al. (2008) imex:IM-11989|pubmed:18724936 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1955956|imex:IM-11989-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014624.1|sgd:S000005378|ensemblfungi:YOL018C(gene)|ensemblfungi:YOL018C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0006675"(mannosyl-inositol phosphorylceramide metabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028673|reactome:R-SCE-6811440|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009306"(protein secretion)|dip:DIP-4244N|mint:Q08144 refseq:NP_010183.1|sgd:S000002258|dip:DIP-3908N|mint:Q12154|ensemblfungi:YDL100C(gene)|ensemblfungi:YDL100C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009408"(response to heat)|go:"GO:0010038"(response to metal ion)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990507"(obsolete ATP-independent chaperone mediated protein folding)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|rcsb pdb:2WOJ|rcsb pdb:3A36|rcsb pdb:3A37|rcsb pdb:3B2E|rcsb pdb:3H84|rcsb pdb:3IDQ|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3SJD|rcsb pdb:3VLC|rcsb pdb:3ZS8|rcsb pdb:3ZS9|rcsb pdb:4PWX|rcsb pdb:4XTR|rcsb pdb:4XVU|rcsb pdb:4XWO|rcsb pdb:5BW8|rcsb pdb:5BWK psi-mi:"MI:0469"(intact) crc64:CEBD6FE11278B1F0 crc64:F795C359B5A4A461 figure legend:Fig. 3A|comment:The coordinates of the transmembrane domain were not given in the paper and instead have been taken from the UniProt entry.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/09/17 2014/10/16 rogid:M7Ezt/D1lvPf/T8TrjQwtKNhFhw559292 rogid:Y+PTDg+beVeCH5mn4BvWi5wBP4A559292 intact-crc:1FC1CB2221C7D073|rigid:5WXaQGOsfwXSK9zN7pvygCY+vyg false necessary binding region:318..318-338..338 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01590 uniprotkb:Q12154 intact:EBI-16930|uniprotkb:D6VY28|ensemblfungi:YLR026C intact:EBI-2989|uniprotkb:Q6B1B6|uniprotkb:D6VRQ0|ensemblfungi:YDL100C psi-mi:sed5_yeast(display_long)|uniprotkb:SED5(gene name)|psi-mi:SED5(display_short)|uniprotkb:YLR026C(locus name) psi-mi:get3_yeast(display_long)|uniprotkb:YDL100C(locus name)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARR4(gene name synonym)|uniprotkb:D2371(orf name)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins 3(gene name synonym)|uniprotkb:Golgi to ER traffic protein 3(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Schuldiner et al. (2008) imex:IM-11989|pubmed:18724936 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-1955912|imex:IM-11989-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013126.1|sgd:S000004016|ensemblfungi:YLR026C(gene)|ensemblfungi:YLR026C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0090083"(regulation of inclusion body assembly)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR021538|rcsb pdb:1MQS|rcsb pdb:1PD0|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-6807878|reactome:R-SCE-6811438|reactome:R-SCE-9609523|go:"GO:0031201"(SNARE complex)|go:"GO:0048278"(vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|dip:DIP-2489N|mint:Q01590 refseq:NP_010183.1|sgd:S000002258|dip:DIP-3908N|mint:Q12154|ensemblfungi:YDL100C(gene)|ensemblfungi:YDL100C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009408"(response to heat)|go:"GO:0010038"(response to metal ion)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990507"(obsolete ATP-independent chaperone mediated protein folding)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|rcsb pdb:2WOJ|rcsb pdb:3A36|rcsb pdb:3A37|rcsb pdb:3B2E|rcsb pdb:3H84|rcsb pdb:3IDQ|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3SJD|rcsb pdb:3VLC|rcsb pdb:3ZS8|rcsb pdb:3ZS9|rcsb pdb:4PWX|rcsb pdb:4XTR|rcsb pdb:4XVU|rcsb pdb:4XWO|rcsb pdb:5BW8|rcsb pdb:5BWK go:"GO:0005737"(cytoplasm) crc64:B3192B57269A0B83 crc64:F795C359B5A4A461 figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/09/17 2014/10/16 rogid:c+W+86qfjxcvWWJ9nMScyH5TjNA559292 rogid:Y+PTDg+beVeCH5mn4BvWi5wBP4A559292 intact-crc:38C37217702E138E|rigid:GaK2AoeIf94Y4oPCx4kdr4Sty40 false green fluorescent protein tag:n-n red fluorescent protein tag:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P40056 uniprotkb:P53192 intact:EBI-22604|uniprotkb:D3DLZ0|ensemblfungi:YER083C intact:EBI-23722|uniprotkb:D6VUB7|ensemblfungi:YGL020C psi-mi:get2_yeast(display_long)|uniprotkb:GET2(gene name)|psi-mi:GET2(display_short)|uniprotkb:HUR2(gene name synonym)|uniprotkb:Required for meiotic nuclear division protein 7(gene name synonym)|uniprotkb:Hydroxyurea resistance protein 2(gene name synonym)|uniprotkb:RMD7(gene name synonym)|uniprotkb:YER083C(locus name)|uniprotkb:Guided entry of tail-anchored proteins 2(gene name synonym) psi-mi:get1_yeast(display_long)|uniprotkb:YGL020C(locus name)|uniprotkb:GET1(gene name)|psi-mi:GET1(display_short)|uniprotkb:Guided entry of tail-anchored proteins 1(gene name synonym)|uniprotkb:MDM39(gene name synonym)|uniprotkb:Mitochondrial distribution and morphology protein 39(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Schuldiner et al. (2008) imex:IM-11989|pubmed:18724936 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1955970|imex:IM-11989-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011006.2|sgd:S000000885|dip:DIP-4508N|mint:P40056|ensemblfungi:YER083C(gene)|ensemblfungi:YER083C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000423"(mitophagy)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|interpro:IPR014802(GET complex, subunit GET2)|interpro:IPR028143|rcsb pdb:3SJD|rcsb pdb:3ZS9 refseq:NP_011495.1|sgd:S000002988|dip:DIP-6309N|mint:P53192|ensemblfungi:YGL020C(gene)|ensemblfungi:YGL020C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|interpro:IPR027538|interpro:IPR028945|interpro:IPR029012|rcsb pdb:3B2E|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3VLC|rcsb pdb:3ZS8 psi-mi:"MI:0469"(intact) crc64:1667E7C879CFB6EA crc64:C43DC5928D97DB7D figure legend:Supp. Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/09/17 2014/10/16 rogid:0LElfYB/qcfATvf9XBE4YVLBaCk559292 rogid:QaFQLKAc5Ki1Xjg8uaCsZr1CQJM559292 intact-crc:8FD1A7190FAAB5ED|rigid:L0l1hjS28INmV6F+XOqqT9qH9P0 false ha tag:?-? tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)