#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q12315 uniprotkb:P12385 intact:EBI-7635|uniprotkb:D6VRE7|ensemblfungi:YDL207W intact:EBI-6533|uniprotkb:D6VQD9|ensemblfungi:YBR143C psi-mi:gle1_yeast(display_long)|uniprotkb:BRR3(gene name synonym)|uniprotkb:RSS1(gene name synonym)|uniprotkb:YDL207W(locus name)|uniprotkb:D1049(orf name)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:Nuclear pore protein GLE1(gene name synonym)|uniprotkb:RNA export factor GLE1(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym) psi-mi:erf1_yeast(display_long)|uniprotkb:SUP45(gene name)|psi-mi:SUP45(display_short)|uniprotkb:SAL4(gene name synonym)|uniprotkb:SUP1(gene name synonym)|uniprotkb:YBR143C(locus name)|uniprotkb:YBR1120(orf name)|uniprotkb:Omnipotent suppressor protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Bolger et al. (2008) imex:IM-11988|pubmed:18724935 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1928244|imex:IM-11988-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002366|refseq:NP_010074.1|mint:Q12315|dip:DIP-2350N|ensemblfungi:YDL207W(gene)|ensemblfungi:YDL207W_mRNA(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:6B4E sgd:S000000347|refseq:NP_009701.3|mint:P12385|dip:DIP-800N|ensemblfungi:YBR143C(gene)|ensemblfungi:YBR143C_mRNA(transcript)|go:"GO:0002184"(cytoplasmic translational termination)|go:"GO:0003747"(translation release factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006415"(translational termination)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016149"(translation release factor activity, codon specific)|go:"GO:0018444"(translation release factor complex)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR004403(Peptide chain release factor eRF/aRF subunit 1)|interpro:IPR005140(eRF1 domain 1)|interpro:IPR005141(eRF1 domain 2)|interpro:IPR005142(eRF1 domain 3)|interpro:IPR024049|interpro:IPR029064|interpro:IPR042226|rcsb pdb:4CRM|rcsb pdb:4CRN|reactome:R-SCE-72764|reactome:R-SCE-975956|reactome:R-SCE-975957 psi-mi:"MI:0469"(intact) crc64:C9C6B1513AF95711 crc64:9B59133EE3B1F61E figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/09/17 2014/10/16 rogid:1RI51/DOenI6DQvh2tErmJnDffI559292 rogid:gy6qwRrMC3d3s/uaS2PzFoK6/Do559292 intact-crc:9C350B75C414A386|rigid:C7PPIgi5SBWju1t2GXRgbcivUN0 false - calmodulin binding peptide plus protein a tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12315 uniprotkb:P05453 intact:EBI-7635|uniprotkb:D6VRE7|ensemblfungi:YDL207W intact:EBI-6540|uniprotkb:P05420|uniprotkb:D6VSF4|ensemblfungi:YDR172W psi-mi:gle1_yeast(display_long)|uniprotkb:BRR3(gene name synonym)|uniprotkb:RSS1(gene name synonym)|uniprotkb:YDL207W(locus name)|uniprotkb:D1049(orf name)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:Nuclear pore protein GLE1(gene name synonym)|uniprotkb:RNA export factor GLE1(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym) psi-mi:erf3_yeast(display_long)|uniprotkb:SUP35(gene name)|psi-mi:SUP35(display_short)|uniprotkb:GST1(gene name synonym)|uniprotkb:PNM2(gene name synonym)|uniprotkb:SAL3(gene name synonym)|uniprotkb:SUF12(gene name synonym)|uniprotkb:SUP2(gene name synonym)|uniprotkb:YDR172W(locus name)|uniprotkb:YD9395.05(orf name)|uniprotkb:ERF2(gene name synonym)|uniprotkb:ERF-3(gene name synonym)|uniprotkb:Translation release factor 3(gene name synonym)|uniprotkb:Polypeptide release factor 3(gene name synonym)|uniprotkb:Omnipotent suppressor protein 2(gene name synonym)|uniprotkb:G1 to S phase transition protein 1(gene name synonym)|uniprotkb:PSI no more protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Bolger et al. (2008) imex:IM-11988|pubmed:18724935 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1954427|imex:IM-11988-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002366|refseq:NP_010074.1|mint:Q12315|dip:DIP-2350N|ensemblfungi:YDL207W(gene)|ensemblfungi:YDL207W_mRNA(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:6B4E sgd:S000002579|refseq:NP_010457.3|mint:P05453|dip:DIP-376N|ensemblfungi:YDR172W(gene)|ensemblfungi:YDR172W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0002184"(cytoplasmic translational termination)|go:"GO:0003729"(mRNA binding)|go:"GO:0003747"(translation release factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006415"(translational termination)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0018444"(translation release factor complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR003285(Yeast eukaryotic release factor)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|rcsb pdb:1YJO|rcsb pdb:1YJP|rcsb pdb:2OMM|rcsb pdb:4CRN|rcsb pdb:5K2E|rcsb pdb:5K2F|rcsb pdb:5K2G|rcsb pdb:5K2H|reactome:R-SCE-72764|reactome:R-SCE-975956|reactome:R-SCE-975957 psi-mi:"MI:0469"(intact) crc64:C9C6B1513AF95711 crc64:43912A6D77DFA153 figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/09/17 2014/10/16 rogid:1RI51/DOenI6DQvh2tErmJnDffI559292 rogid:R4xSkfzHnSuHRDxWOd2dWMEuseI559292 intact-crc:6A8CB3C1907BBC88|rigid:LsElAdVDnsG6z9yMQa4JhCFQOZ8 false - calmodulin binding peptide plus protein a tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q53GS7 uniprotkb:P06103 intact:EBI-1955541|uniprotkb:O75458|uniprotkb:Q53GT9|uniprotkb:Q5VVU1|uniprotkb:Q8NCP6|uniprotkb:Q9UFL6|ensembl:ENSP00000308622 intact:EBI-8973|ensemblfungi:YOR361C|uniprotkb:D6W356 psi-mi:gle1_human(display_long)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:GLE1L(gene name synonym)|uniprotkb:GLE1-like protein(gene name synonym)|uniprotkb:GLE1 RNA export mediator(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym) psi-mi:eif3b_yeast(display_long)|uniprotkb:YOR361C(locus name)|uniprotkb:PRT1(gene name)|psi-mi:PRT1(display_short)|uniprotkb:CDC63(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 90 kDa subunit(gene name synonym)|uniprotkb:Translation initiation factor eIF3 p90 subunit(gene name synonym)|uniprotkb:Cell cycle regulation and translation initiation protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Bolger et al. (2008) imex:IM-11988|pubmed:18724935 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1955784|imex:IM-11988-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003722.1|refseq:NP_001490.1|ensembl:ENSG00000119392(gene)|ensembl:ENST00000309971(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:6B4F|rcsb pdb:6B4I|rcsb pdb:6B4J|reactome:R-HSA-159236 ensemblfungi:YOR361C(gene)|ensemblfungi:YOR361C_mRNA(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR011400(Translation initiation factor eIF-3b)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034363|interpro:IPR035979|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:3NS5|rcsb pdb:3NS6|rcsb pdb:3ZWL|rcsb pdb:4U1E|rcsb pdb:4U1F|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6ZCE|rcsb pdb:6ZU9|reactome:R-SCE-156827|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|refseq:NP_015006.3|sgd:S000005888|mint:P06103|dip:DIP-2519N psi-mi:"MI:0469"(intact) - crc64:F5E4E783408EE948 figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/09/17 2014/10/16 rogid:wdG5CPG2bIFZun0cyQ9jyPK7e9s9606 rogid:KeOY80g2TW3axiQNc1iJhsqEUPM559292 intact-crc:4C6C2D7664BA179F|rigid:NiSXdm36Nsz4WDAkuofW6xZ/M+c false - calmodulin binding peptide plus protein a tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P05453 uniprotkb:Q12315 intact:EBI-6540|uniprotkb:P05420|uniprotkb:D6VSF4|ensemblfungi:YDR172W intact:EBI-7635|uniprotkb:D6VRE7|ensemblfungi:YDL207W psi-mi:erf3_yeast(display_long)|uniprotkb:SUP35(gene name)|psi-mi:SUP35(display_short)|uniprotkb:GST1(gene name synonym)|uniprotkb:PNM2(gene name synonym)|uniprotkb:SAL3(gene name synonym)|uniprotkb:SUF12(gene name synonym)|uniprotkb:SUP2(gene name synonym)|uniprotkb:YDR172W(locus name)|uniprotkb:YD9395.05(orf name)|uniprotkb:ERF2(gene name synonym)|uniprotkb:ERF-3(gene name synonym)|uniprotkb:Translation release factor 3(gene name synonym)|uniprotkb:Polypeptide release factor 3(gene name synonym)|uniprotkb:Omnipotent suppressor protein 2(gene name synonym)|uniprotkb:G1 to S phase transition protein 1(gene name synonym)|uniprotkb:PSI no more protein 2(gene name synonym) psi-mi:gle1_yeast(display_long)|uniprotkb:BRR3(gene name synonym)|uniprotkb:RSS1(gene name synonym)|uniprotkb:YDL207W(locus name)|uniprotkb:D1049(orf name)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:Nuclear pore protein GLE1(gene name synonym)|uniprotkb:RNA export factor GLE1(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym) psi-mi:"MI:0096"(pull down) Bolger et al. (2008) imex:IM-11988|pubmed:18724935 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1955006|imex:IM-11988-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002579|refseq:NP_010457.3|mint:P05453|dip:DIP-376N|ensemblfungi:YDR172W(gene)|ensemblfungi:YDR172W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0002184"(cytoplasmic translational termination)|go:"GO:0003729"(mRNA binding)|go:"GO:0003747"(translation release factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006415"(translational termination)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0018444"(translation release factor complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR003285(Yeast eukaryotic release factor)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|rcsb pdb:1YJO|rcsb pdb:1YJP|rcsb pdb:2OMM|rcsb pdb:4CRN|rcsb pdb:5K2E|rcsb pdb:5K2F|rcsb pdb:5K2G|rcsb pdb:5K2H|reactome:R-SCE-72764|reactome:R-SCE-975956|reactome:R-SCE-975957 sgd:S000002366|refseq:NP_010074.1|mint:Q12315|dip:DIP-2350N|ensemblfungi:YDL207W(gene)|ensemblfungi:YDL207W_mRNA(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:6B4E psi-mi:"MI:0469"(intact) crc64:43912A6D77DFA153 crc64:C9C6B1513AF95711 figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/09/17 2014/10/16 rogid:R4xSkfzHnSuHRDxWOd2dWMEuseI559292 rogid:1RI51/DOenI6DQvh2tErmJnDffI559292 intact-crc:0A4997C095CA5981|rigid:LsElAdVDnsG6z9yMQa4JhCFQOZ8 false glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P06103 uniprotkb:Q12315 intact:EBI-8973|ensemblfungi:YOR361C|uniprotkb:D6W356 intact:EBI-7635|uniprotkb:D6VRE7|ensemblfungi:YDL207W psi-mi:eif3b_yeast(display_long)|uniprotkb:YOR361C(locus name)|uniprotkb:PRT1(gene name)|psi-mi:PRT1(display_short)|uniprotkb:CDC63(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 90 kDa subunit(gene name synonym)|uniprotkb:Translation initiation factor eIF3 p90 subunit(gene name synonym)|uniprotkb:Cell cycle regulation and translation initiation protein(gene name synonym) psi-mi:gle1_yeast(display_long)|uniprotkb:BRR3(gene name synonym)|uniprotkb:RSS1(gene name synonym)|uniprotkb:YDL207W(locus name)|uniprotkb:D1049(orf name)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:Nuclear pore protein GLE1(gene name synonym)|uniprotkb:RNA export factor GLE1(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym) psi-mi:"MI:0096"(pull down) Bolger et al. (2008) imex:IM-11988|pubmed:18724935 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1955816|imex:IM-11988-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR361C(gene)|ensemblfungi:YOR361C_mRNA(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR011400(Translation initiation factor eIF-3b)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034363|interpro:IPR035979|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:3NS5|rcsb pdb:3NS6|rcsb pdb:3ZWL|rcsb pdb:4U1E|rcsb pdb:4U1F|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6ZCE|rcsb pdb:6ZU9|reactome:R-SCE-156827|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|refseq:NP_015006.3|sgd:S000005888|mint:P06103|dip:DIP-2519N sgd:S000002366|refseq:NP_010074.1|mint:Q12315|dip:DIP-2350N|ensemblfungi:YDL207W(gene)|ensemblfungi:YDL207W_mRNA(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:6B4E psi-mi:"MI:0469"(intact) crc64:F5E4E783408EE948 crc64:C9C6B1513AF95711 figure legend:Fig. 4C|comment:Interaction is independent of RNA binding|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/09/17 2014/10/16 rogid:KeOY80g2TW3axiQNc1iJhsqEUPM559292 rogid:1RI51/DOenI6DQvh2tErmJnDffI559292 intact-crc:7ECA04B929C5C0B4|rigid:dyFGFjyx5zOMGeKPxoTN+MRmHis false glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q04067 uniprotkb:Q12315 intact:EBI-8958|ensemblfungi:YDR429C|uniprotkb:D6VT58 intact:EBI-7635|uniprotkb:D6VRE7|ensemblfungi:YDL207W psi-mi:eif3g_yeast(display_long)|uniprotkb:TIF35(gene name)|psi-mi:TIF35(display_short)|uniprotkb:YDR429C(locus name)|uniprotkb:D9461.16(orf name)|uniprotkb:Eukaryotic translation initiation factor 3 RNA-binding subunit(gene name synonym)|uniprotkb:Translation initiation factor eIF3 p33 subunit(gene name synonym) psi-mi:gle1_yeast(display_long)|uniprotkb:BRR3(gene name synonym)|uniprotkb:RSS1(gene name synonym)|uniprotkb:YDL207W(locus name)|uniprotkb:D1049(orf name)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:Nuclear pore protein GLE1(gene name synonym)|uniprotkb:RNA export factor GLE1(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym) psi-mi:"MI:0096"(pull down) Bolger et al. (2008) imex:IM-11988|pubmed:18724935 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1955824|imex:IM-11988-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDR429C(gene)|ensemblfungi:YDR429C_mRNA(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006415"(translational termination)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017334(Translation initiation factor 3, RNA-binding subunit)|interpro:IPR024675|interpro:IPR034240|interpro:IPR035979|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:4U1E|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6ZCE|rcsb pdb:6ZU9|reactome:R-SCE-156827|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|refseq:NP_010717.1|sgd:S000002837|mint:Q04067|dip:DIP-1704N sgd:S000002366|refseq:NP_010074.1|mint:Q12315|dip:DIP-2350N|ensemblfungi:YDL207W(gene)|ensemblfungi:YDL207W_mRNA(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:6B4E psi-mi:"MI:0469"(intact) crc64:340A5285F2C84E06 crc64:C9C6B1513AF95711 figure legend:Fig. 4C|comment:Interaction is independent of RNA binding|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/09/17 2014/10/16 rogid:v7lKonGYtSi5ZT4abzAzES8VLAk559292 rogid:1RI51/DOenI6DQvh2tErmJnDffI559292 intact-crc:C6375FB57C93AE10|rigid:hSkcHR4R87MqSiNFEsjVQ0GyBGE false glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q53GS7 uniprotkb:O00303 intact:EBI-1955541|uniprotkb:O75458|uniprotkb:Q53GT9|uniprotkb:Q5VVU1|uniprotkb:Q8NCP6|uniprotkb:Q9UFL6|ensembl:ENSP00000308622 intact:EBI-711990|ensembl:ENSP00000431800|ensembl:ENSP00000499218|uniprotkb:Q6IB45|uniprotkb:Q8N978|uniprotkb:A8K0S2 psi-mi:gle1_human(display_long)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:GLE1L(gene name synonym)|uniprotkb:GLE1-like protein(gene name synonym)|uniprotkb:GLE1 RNA export mediator(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym) psi-mi:eif3f_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 5(gene name synonym)|uniprotkb:eIF-3-epsilon(gene name synonym)|uniprotkb:eIF3 p47(gene name synonym)|uniprotkb:EIF3F(gene name)|psi-mi:EIF3F(display_short)|uniprotkb:EIF3S5(gene name synonym)|uniprotkb:Deubiquitinating enzyme eIF3f(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bolger et al. (2008) imex:IM-11988|pubmed:18724935 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1955532|imex:IM-11988-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003722.1|refseq:NP_001490.1|ensembl:ENSG00000119392(gene)|ensembl:ENST00000309971(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:6B4F|rcsb pdb:6B4I|rcsb pdb:6B4J|reactome:R-HSA-159236 ensembl:ENSG00000175390(gene)|ensembl:ENST00000533626(transcript)|ensembl:ENST00000651655(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR027531|interpro:IPR037518|mint:O00303|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_003745.1|dip:DIP-35580N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/09/17 2014/10/16 rogid:wdG5CPG2bIFZun0cyQ9jyPK7e9s9606 rogid:dpH1pTcPshcrSjNCdPPnkYiW0YU9606 intact-crc:2E30AF9A423651EF|rigid:RkGCNwGodtHsaDwXVYxgK52TI9Q false green fluorescent protein tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)