#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P47050	uniprotkb:P15731	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	intact:EBI-19735|uniprotkb:D6VQ81|ensemblfungi:YBR082C	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:ubc4_yeast(display_long)|uniprotkb:UBC4(gene name)|psi-mi:UBC4(display_short)|uniprotkb:YBR082C(locus name)|uniprotkb:YBR0745(orf name)|uniprotkb:Ubiquitin-protein ligase 4(gene name synonym)|uniprotkb:Ubiquitin carrier protein 4(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Zaidi et al. (2008)	pubmed:18704118|imex:IM-9559|mint:MINT-6802293|doi:10.1038/embor.2008.155	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8056851|mint:MINT-6802300|imex:IM-9559-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|mint:MINT-6802303(identity)	refseq:NP_009638.1|sgd:S000000286|ensemblfungi:YBR082C(gene)|ensemblfungi:YBR082C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070628"(proteasome binding)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1QCQ|rcsb pdb:5AIE|reactome:R-SCE-8866652|reactome:R-SCE-8866654|reactome:R-SCE-9033241|reactome:R-SCE-983168|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|dip:DIP-6596N|mint:P15731|mint:MINT-6802302(identity)	-	crc64:A86A48F6DC6AF163	crc64:8E96137D3EB20F80	figure legend:f1d|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/28	2014/10/16	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rogid:MCFIl+wHw5tAv9OvK57xg0aZBx4559292	intact-crc:44E274C0A2C46A91|rigid:Mbk1809krsFKbDOzXxoLrxtJVyo	false	ha tag:?-?(MINT-6802308)	glutathione s tranferase tag:?-?(MINT-6802304)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47050	uniprotkb:P06104	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	intact:EBI-19722|uniprotkb:D6VU83|ensemblfungi:YGL058W	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:ubc2_yeast(display_long)|uniprotkb:RAD6(gene name)|psi-mi:RAD6(display_short)|uniprotkb:UBC2(gene name synonym)|uniprotkb:Ubiquitin-protein ligase UBC2(gene name synonym)|uniprotkb:Ubiquitin carrier protein UBC2(gene name synonym)|uniprotkb:Radiation sensitivity protein 6(gene name synonym)|uniprotkb:YGL058W(locus name)|uniprotkb:E2 ubiquitin-conjugating enzyme 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Zaidi et al. (2008)	pubmed:18704118|imex:IM-9559|mint:MINT-6802293|doi:10.1038/embor.2008.155	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8056929|mint:MINT-6802325|imex:IM-9559-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|mint:MINT-6802331(identity)	refseq:NP_011457.1|sgd:S000003026|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033503"(HULC complex)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042275"(error-free postreplication DNA repair)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070628"(proteasome binding)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|go:"GO:0090089"(regulation of dipeptide transport)|go:"GO:0097505"(Rad6-Rad18 complex)|go:"GO:0120174"(stress-induced homeostatically regulated protein degradation pathway)|go:"GO:1990303"(UBR1-RAD6 ubiquitin ligase complex)|go:"GO:1990304"(MUB1-RAD6-UBR2 ubiquitin ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1AYZ|rcsb pdb:4R62|reactome:R-SCE-8866652|reactome:R-SCE-8866654|reactome:R-SCE-983168|ensemblfungi:YGL058W(gene)|ensemblfungi:YGL058W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|dip:DIP-1555N|mint:P06104|mint:MINT-6802327(identity)	-	crc64:A86A48F6DC6AF163	crc64:5F568DC28ABBD60F	figure legend:f1d|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/28	2014/10/16	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rogid:NHteg3G6/ga0Apqc/vkqrJJURwg559292	intact-crc:1B9F5F5EA0B8D848|rigid:lOoI5ch+fY2yH08B8I711OvrH90	false	ha tag:?-?(MINT-6802332)	glutathione s tranferase tag:?-?(MINT-6802328)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14682	uniprotkb:P47050	intact:EBI-19730|uniprotkb:D6VS40|ensemblfungi:YDR054C	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	psi-mi:ubc3_yeast(display_long)|uniprotkb:CDC34(gene name)|psi-mi:CDC34(display_short)|uniprotkb:UBC3(gene name synonym)|uniprotkb:DNA6(gene name synonym)|uniprotkb:YDR054C(locus name)|uniprotkb:YD9609.08C(orf name)|uniprotkb:D4211(orf name)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Cell division control protein 34(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC34(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 3(gene name synonym)	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:"MI:0096"(pull down)	Zaidi et al. (2008)	pubmed:18704118|imex:IM-9559|mint:MINT-6802293|doi:10.1038/embor.2008.155	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8056892|mint:MINT-6802313|imex:IM-9559-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010339.1|sgd:S000002461|ensemblfungi:YDR054C(gene)|ensemblfungi:YDR054C_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:6NYA|rcsb pdb:6NYD|rcsb pdb:7K5J|reactome:R-SCE-8866652|reactome:R-SCE-983168|dip:DIP-1618N|mint:P14682|mint:MINT-6802319(identity)	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|mint:MINT-6802315(identity)	-	crc64:1CE3E0C3AB1436DC	crc64:A86A48F6DC6AF163	figure legend:f1d|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/28	2014/10/16	rogid:1GaQJnMKE90j9Egn6PJsANrxSzg559292	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	intact-crc:A9D8A3BB05BB74CF|rigid:OuWCLGQP6lRiXR1mYAsRqq15AMI	false	glutathione s tranferase tag:?-?(MINT-6802320)	ha tag:?-?(MINT-6802316)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P0CG63	uniprotkb:P15873	intact:EBI-7000452|ensemblfungi:YLL039C|intact:MINT-545233|uniprotkb:D6VXW7|uniprotkb:P61864|uniprotkb:Q6LA96|uniprotkb:P04838	intact:EBI-12993|uniprotkb:D6VQ89|ensemblfungi:YBR088C	psi-mi:ubi4p_yeast(display_long)|uniprotkb:UBI4(gene name)|psi-mi:UBI4(display_short)|uniprotkb:SCD2(gene name synonym)|uniprotkb:YLL039C(locus name)	psi-mi:pcna_yeast(display_long)|uniprotkb:YBR0811(orf name)|uniprotkb:YBR088C(locus name)|uniprotkb:POL30(gene name)|psi-mi:POL30(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Zaidi et al. (2008)	pubmed:18704118|imex:IM-9559|mint:MINT-6802293|doi:10.1038/embor.2008.155	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8056985|mint:MINT-6802340|imex:IM-9559-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLL039C(gene)|ensemblfungi:YLL039C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:1OTR|rcsb pdb:1Q0W|rcsb pdb:1WR1|rcsb pdb:1ZW7|rcsb pdb:2G3Q|rcsb pdb:2JT4|rcsb pdb:2JWZ|rcsb pdb:2KDI|rcsb pdb:2L00|rcsb pdb:3CMM|rcsb pdb:3L0W|rcsb pdb:3L10|rcsb pdb:3OLM|rcsb pdb:4HCN|rcsb pdb:4NNJ|rcsb pdb:4Q5E|rcsb pdb:4Q5H|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-156827|reactome:R-SCE-174113|reactome:R-SCE-1799339|reactome:R-SCE-532668|reactome:R-SCE-5358346|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5687128|reactome:R-SCE-5689603|reactome:R-SCE-5689877|reactome:R-SCE-5689880|reactome:R-SCE-5689901|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6791226|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-72649|reactome:R-SCE-72689|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72706|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8866652|reactome:R-SCE-8866654|reactome:R-SCE-8948747|reactome:R-SCE-8948751|reactome:R-SCE-901032|reactome:R-SCE-9020702|reactome:R-SCE-9033241|reactome:R-SCE-917729|reactome:R-SCE-9646399|reactome:R-SCE-975956|reactome:R-SCE-975957|reactome:R-SCE-983168|interpro:IPR000626(Ubiquitin)|sgd:S000003962|interpro:IPR019956|interpro:IPR019954|refseq:NP_013061.1|interpro:IPR029071|mint:P0CG63|mint:MINT-6802343(identity)	refseq:NP_009645.1|sgd:S000000292|go:"GO:0043626"(PCNA complex)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:1902394"(positive regulation of exodeoxyribonuclease activity)|go:"GO:1903022"(positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands)|go:"GO:1905779"(positive regulation of exonuclease activity)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|rcsb pdb:1PLQ|rcsb pdb:1PLR|rcsb pdb:1SXJ|rcsb pdb:2OD8|rcsb pdb:3F1W|rcsb pdb:3GPM|rcsb pdb:3GPN|rcsb pdb:3L0W|rcsb pdb:4L6P|rcsb pdb:3L0X|rcsb pdb:3L10|rcsb pdb:4YHR|rcsb pdb:3PGE|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:5JNE|rcsb pdb:4L60|mint:P15873|dip:DIP-2417N|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|ensemblfungi:YBR088C(gene)|ensemblfungi:YBR088C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|rcsb pdb:5T9D|rcsb pdb:5V7K|rcsb pdb:5V7M|rcsb pdb:5ZUT|rcsb pdb:6CX2|rcsb pdb:6CX3|rcsb pdb:6CX4|rcsb pdb:6D0Q|rcsb pdb:6D0R|rcsb pdb:6E49|rcsb pdb:6W9W|rcsb pdb:6WAC|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-4615885|reactome:R-SCE-5358565|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183|reactome:R-SCE-8866654|rcsb pdb:5V7L|mint:MINT-6802342(identity)	-	function:Protein modifier which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Attachment to proteins as a Lys-48-linked polymer usually leads to their degradation by proteasome. Attachment to proteins as a monomer or as an alternatively linked polymer does not lead to proteasomal degradation and may be required for numerous functions, including maintenance of chromatin structure, regulation of gene expression, stress response, ribosome biogenesis and DNA repair|comment:mint	crc64:9B56C5851621DDDC	figure legend:f2d|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2008/11/28	2014/10/16	rogid:+GNv/Jc7C11q8cgu2qZ6YkcsIeI559292	rogid:/+XSPV99OBBwBBC/nY0JiHaAeSI559292	intact-crc:CFA041536562B9E1|rigid:g57N0RECh4COboFuOawfvqFHYkA	false	-	his tag:?-?(MINT-6802347)	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P47050	uniprotkb:Q08226	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	intact:EBI-30025|uniprotkb:Q6B2N4|uniprotkb:Q7LGP7|uniprotkb:D6W204|ensemblfungi:YOL063C	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:crt10_yeast(display_long)|uniprotkb:Constitutive RNR transcription regulator 10(gene name synonym)|uniprotkb:YOL063C(locus name)|uniprotkb:CRT10(gene name)|psi-mi:CRT10(display_short)	psi-mi:"MI:0096"(pull down)	Zaidi et al. (2008)	pubmed:18704118|imex:IM-9559|mint:MINT-6802293|doi:10.1038/embor.2008.155	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8057066|mint:MINT-6802398|imex:IM-9559-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|mint:MINT-6802404(identity)	refseq:NP_014578.1|sgd:S000005424|dip:DIP-2832N|mint:Q08226|ensemblfungi:YOL063C(gene)|ensemblfungi:YOL063C_mRNA(transcript)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR014839(Ribonucleotide reductase, transcriptional regulator CRT10)|mint:MINT-6802400(identity)	-	crc64:A86A48F6DC6AF163	-	figure legend:f4a|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2008/11/28	2014/10/16	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rogid:ADovI2G3LpE+lM1nwElxAySzmfM559292	intact-crc:88332104190A036F|rigid:pnibFtfQSjM9phKMe6F3h0r/Tjg	false	tandem tag:?-?(MINT-6802407)|binding-associated region:1-50(MINT-6802405)	tag:?-?(MINT-6802401)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P47050	uniprotkb:Q06211	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	intact:EBI-38894|uniprotkb:D6W4G5|ensemblfungi:YPR164W	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:mms1_yeast(display_long)|uniprotkb:Synthetically lethal with MCM10 protein 6(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 108(gene name synonym)|uniprotkb:MMS1(gene name)|psi-mi:MMS1(display_short)|uniprotkb:KIM3(gene name synonym)|uniprotkb:SLM6(gene name synonym)|uniprotkb:RTT108(gene name synonym)|uniprotkb:YPR164W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Zaidi et al. (2008)	pubmed:18704118|imex:IM-9559|mint:MINT-6802293|doi:10.1038/embor.2008.155	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8057030|mint:MINT-6802372|imex:IM-9559-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|mint:MINT-6802374(identity)	sgd:S000006368|refseq:NP_015490.1|mint:Q06211|dip:DIP-6310N|ensemblfungi:YPR164W(gene)|ensemblfungi:YPR164W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|mint:MINT-6802378(identity)	-	crc64:A86A48F6DC6AF163	crc64:CC698C422631A7D7	figure legend:f3a|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2008/11/28	2014/10/16	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rogid:/uLxndTAdpoXEanqM0IDRzaN7/0559292	intact-crc:AFFE7CA242192708|rigid:yoWEjB+Jcgvdfv0a/iJMefXgtt0	false	tandem tag:?-?(MINT-6802375)|binding-associated region:1-50(MINT-6802386)	tag:?-?(MINT-6802395)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P47050	uniprotkb:Q06164	intact:EBI-25861|uniprotkb:D6VWD7|ensemblfungi:YJL047C	intact:EBI-31156|uniprotkb:D6VYW3|ensemblfungi:YLR320W	psi-mi:cul8_yeast(display_long)|uniprotkb:RTT101(gene name)|psi-mi:RTT101(display_short)|uniprotkb:CUL8(gene name synonym)|uniprotkb:Cullin-C(gene name synonym)|uniprotkb:Regulator of Ty1 transposition protein 101(gene name synonym)|uniprotkb:J1166(orf name)|uniprotkb:YJL047C(locus name)	psi-mi:mms22_yeast(display_long)|uniprotkb:MMS22(gene name)|psi-mi:MMS22(display_short)|uniprotkb:Synthetically lethal with MCM10 protein 2(gene name synonym)|uniprotkb:SLM2(gene name synonym)|uniprotkb:YLR320W(locus name)|uniprotkb:Methyl methanesulfonate-sensitivity protein 22(gene name synonym)	psi-mi:"MI:0096"(pull down)	Zaidi et al. (2008)	pubmed:18704118|imex:IM-9559|mint:MINT-6802293|doi:10.1038/embor.2008.155	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8057130|mint:MINT-6802418|imex:IM-9559-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003583|refseq:NP_012488.3|mint:P47050|dip:DIP-2887N|ensemblfungi:YJL047C(gene)|ensemblfungi:YJL047C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0070651"(nonfunctional rRNA decay)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR036317|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|mint:MINT-6802424(identity)	refseq:NP_013424.1|sgd:S000004312|ensemblfungi:YLR320W(gene)|ensemblfungi:YLR320W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|interpro:IPR013220(MMS22)|interpro:IPR019021|rcsb pdb:6J0X|dip:DIP-6567N|mint:Q06164|mint:MINT-6802420(identity)	-	crc64:A86A48F6DC6AF163	crc64:EE9797D4A12A7488	figure legend:f4b|comment:Interaction occurs only in cells treated with MMS.|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2008/11/28	2014/10/16	rogid:Dt2biHwRvkZgQNrr8j8T01QAdXQ559292	rogid:LTGLdBgdnoxfg5emjK+gOqC9py8559292	intact-crc:A706C026C78BF52F|rigid:yUYtXCNZuS6DvNwocLL9jKVyO8U	false	tandem tag:?-?(MINT-6802425)|binding-associated region:1-50(MINT-6802427)	tag:?-?(MINT-6802421)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)