#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9SP32	uniprotkb:Q8W4D8	intact:EBI-632627|uniprotkb:Q9FDY6|uniprotkb:Q9MAN0|ensemblplants:AT1G01040.1	intact:EBI-2015534|uniprotkb:Q9LJU3|ensemblplants:AT3G20550.1	psi-mi:dcl1_arath(display_long)|uniprotkb:Protein CARPEL FACTORY(gene name synonym)|uniprotkb:Protein SHORT INTEGUMENTS 1(gene name synonym)|uniprotkb:Protein SUSPENSOR 1(gene name synonym)|uniprotkb:DCL1(gene name)|psi-mi:DCL1(display_short)|uniprotkb:ASU1(gene name synonym)|uniprotkb:SUS1(gene name synonym)|uniprotkb:At1g01040(locus name)|uniprotkb:T25K16.4(orf name)|uniprotkb:CAF SIN1(gene name synonym)|uniprotkb:Dicer-like protein 1(gene name synonym)|uniprotkb:Protein ABNORMAL SUSPENSOR 1(gene name synonym)	psi-mi:ddl_arath(display_long)|uniprotkb:DDL(gene name)|psi-mi:DDL(display_short)|uniprotkb:Protein DAWDLE(gene name synonym)|uniprotkb:At3g20550(locus name)|uniprotkb:K10D20.9(orf name)	psi-mi:"MI:0018"(two hybrid)	Yu et al. (2008)	pubmed:18632581|imex:IM-9659	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-2015544|imex:IM-9659-1|dip:DIP-88406E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_171612.1|ensemblplants:AT1G01040(gene)|ensemblplants:AT1G01040.1(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0046872"(metal ion binding)|interpro:IPR000999(Ribonuclease III)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR005034(Protein of unknown function DUF283)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR011907(Ribonuclease III, bacterial)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR036085|interpro:IPR036389|interpro:IPR038248|rcsb pdb:2LRS|dip:DIP-33454N	refseq:NP_188691.1|dip:DIP-46412N|ensemblplants:AT3G20550(gene)|ensemblplants:AT3G20550.1(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0048638"(regulation of developmental growth)|go:"GO:0051301"(cell division)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|rcsb pdb:3VPY	imex:"MI:0465"(imex source)	-	-	figure legend:Figure 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/10/21	2017/06/30	rogid:LkUCHo3RF/ObnDA8H1bUySrdID43702	rogid:xonMX5XqMUbfume+szpd5ajJ0ZM3702	intact-crc:6FE82BF1EB3EE8EB|rigid:O3OsVdI0VdyrB6EMMxo7B/4GZAU	false	necessary binding region:1-833	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9SP32	uniprotkb:Q8W4D8	intact:EBI-632627|uniprotkb:Q9FDY6|uniprotkb:Q9MAN0|ensemblplants:AT1G01040.1	intact:EBI-2015534|uniprotkb:Q9LJU3|ensemblplants:AT3G20550.1	psi-mi:dcl1_arath(display_long)|uniprotkb:Protein CARPEL FACTORY(gene name synonym)|uniprotkb:Protein SHORT INTEGUMENTS 1(gene name synonym)|uniprotkb:Protein SUSPENSOR 1(gene name synonym)|uniprotkb:DCL1(gene name)|psi-mi:DCL1(display_short)|uniprotkb:ASU1(gene name synonym)|uniprotkb:SUS1(gene name synonym)|uniprotkb:At1g01040(locus name)|uniprotkb:T25K16.4(orf name)|uniprotkb:CAF SIN1(gene name synonym)|uniprotkb:Dicer-like protein 1(gene name synonym)|uniprotkb:Protein ABNORMAL SUSPENSOR 1(gene name synonym)	psi-mi:ddl_arath(display_long)|uniprotkb:DDL(gene name)|psi-mi:DDL(display_short)|uniprotkb:Protein DAWDLE(gene name synonym)|uniprotkb:At3g20550(locus name)|uniprotkb:K10D20.9(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Yu et al. (2008)	pubmed:18632581|imex:IM-9659	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-2015557|imex:IM-9659-3|dip:DIP-88406E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_171612.1|ensemblplants:AT1G01040(gene)|ensemblplants:AT1G01040.1(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0046872"(metal ion binding)|interpro:IPR000999(Ribonuclease III)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR005034(Protein of unknown function DUF283)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR011907(Ribonuclease III, bacterial)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR036085|interpro:IPR036389|interpro:IPR038248|rcsb pdb:2LRS|dip:DIP-33454N	refseq:NP_188691.1|dip:DIP-46412N|ensemblplants:AT3G20550(gene)|ensemblplants:AT3G20550.1(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0048638"(regulation of developmental growth)|go:"GO:0051301"(cell division)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|rcsb pdb:3VPY	imex:"MI:0465"(imex source)	-	-	figure legend:Figure 5B|caution:"The authors cautioned \"it should be noted that only a small portion of the inputHA-DDL was associated with DCL1-YFP in this assay. In fact, HA-DDL was not detected in the DCL1-YFP immunoprecipitate when the levels of DCL1-YFP were low (i.e., in the absence of p19). These observations suggested that only a portion of DCL1 molecules could interact with DDL or that DDL interacted transiently with DCL1\"."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4100(nicbe)|taxid:4100(Nicotiana benthamiana)	-	2008/10/21	2017/06/30	rogid:LkUCHo3RF/ObnDA8H1bUySrdID43702	rogid:xonMX5XqMUbfume+szpd5ajJ0ZM3702	intact-crc:12AFD9ACE04C1061|rigid:O3OsVdI0VdyrB6EMMxo7B/4GZAU	false	green fluorescent protein tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
intact:EBI-2015602	uniprotkb:Q8W4D8	-	intact:EBI-2015534|uniprotkb:Q9LJU3|ensemblplants:AT3G20550.1	psi-mi:mir162b-arath-rna(display_short)|psi-mi:EBI-2015602(display_long)	psi-mi:ddl_arath(display_long)|uniprotkb:DDL(gene name)|psi-mi:DDL(display_short)|uniprotkb:Protein DAWDLE(gene name synonym)|uniprotkb:At3g20550(locus name)|uniprotkb:K10D20.9(orf name)	psi-mi:"MI:0096"(pull down)	Yu et al. (2008)	pubmed:18632581|imex:IM-9659	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-2015605|imex:IM-9659-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	genbank_protein_gi:71041418(primary-reference)	refseq:NP_188691.1|dip:DIP-46412N|ensemblplants:AT3G20550(gene)|ensemblplants:AT3G20550.1(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0048638"(regulation of developmental growth)|go:"GO:0051301"(cell division)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|rcsb pdb:3VPY	-	-	-	figure legend:Figure 7A Figure 7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/10/21	2017/06/30	crc64:D15D40BCFBDD532F	rogid:xonMX5XqMUbfume+szpd5ajJ0ZM3702	intact-crc:654653555FF3CBB2	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q9NRR4	uniprotkb:Q8TAD8	intact:EBI-528367|uniprotkb:Q7Z5V2|uniprotkb:Q86YH0|uniprotkb:Q9NW73|uniprotkb:Q9Y2V9|uniprotkb:Q9Y4Y0|intact:EBI-10973107|uniprotkb:E7EMP9|ensembl:ENSP00000339845|ensembl:ENSP00000425979	intact:EBI-749336|uniprotkb:Q96SP9|uniprotkb:Q9H9T7|intact:EBI-1046254|ensembl:ENSP00000296215	psi-mi:rnc_human(display_long)|uniprotkb:Ribonuclease III(gene name synonym)|uniprotkb:DROSHA(gene name)|psi-mi:DROSHA(display_short)|uniprotkb:p241(gene name synonym)|uniprotkb:RNASEN(gene name synonym)|uniprotkb:RN3(gene name synonym)|uniprotkb:RNASE3L(gene name synonym)|uniprotkb:Protein Drosha(gene name synonym)	psi-mi:snip1_human(display_long)|uniprotkb:SNIP1(gene name)|psi-mi:SNIP1(display_short)|uniprotkb:FHA domain-containing protein SNIP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Yu et al. (2008)	pubmed:18632581|imex:IM-9659	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-2015619|imex:IM-9659-2|dip:DIP-88407E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001093882.1|refseq:NP_037367.3|refseq:XP_005248348.1|refseq:XP_005248351.1|ensembl:ENSG00000113360(gene)|ensembl:ENST00000344624(transcript)|ensembl:ENST00000511367(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070877"(microprocessor complex)|go:"GO:0070878"(primary miRNA binding)|go:"GO:2000628"(regulation of miRNA metabolic process)|interpro:IPR000999(Ribonuclease III)|interpro:IPR011907(Ribonuclease III, bacterial)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036389|interpro:IPR044442|rcsb pdb:2KHX|rcsb pdb:2NA2|rcsb pdb:5B16|rcsb pdb:6LXD|rcsb pdb:6LXE|rcsb pdb:6V5B|rcsb pdb:6V5C|reactome:R-HSA-203927|dip:DIP-33300N	refseq:NP_078976.2|ensembl:ENSG00000163877(gene)|ensembl:ENST00000296215(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-38956N|mint:Q8TAD8|rcsb pdb:5Z56|rcsb pdb:5Z57|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5Z58|rcsb pdb:6FF7|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0071005"(U2-type precatalytic spliceosome)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)	psi-mi:"MI:0465"(dip)	-	-	figure legend:Figure  6D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/10/21	2017/06/30	rogid:vHfmSHxD1M/Sh4dbo2S7FBaE+eQ9606	rogid:2UWnTY01RhPuUx3PepGug23l11U9606	intact-crc:E7525854C15E78C0|rigid:wd7VzXEFOGYgyifKk6R8ekQ00kA	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)