#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P15036	uniprotkb:Q15672	intact:EBI-1646991|uniprotkb:D3DSH6|uniprotkb:A6NM68|uniprotkb:Q53Y89|ensembl:ENSP00000353344|ensembl:ENSP00000354194|ensembl:ENSP00000499226|ensembl:ENSP00000499315|ensembl:ENSP00000499775	intact:EBI-1797287|uniprotkb:Q92487|uniprotkb:Q99804|uniprotkb:A4D128|ensembl:ENSP00000242261	psi-mi:ets2_human(display_long)|uniprotkb:ETS2(gene name)|psi-mi:ETS2(display_short)	psi-mi:twst1_human(display_long)|uniprotkb:H-twist(gene name synonym)|uniprotkb:TWIST1(gene name)|psi-mi:TWIST1(display_short)|uniprotkb:TWIST(gene name synonym)|uniprotkb:BHLHA38(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 38(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ansieau et al. (2008)	imex:IM-12059|pubmed:18598946	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1797303|imex:IM-12059-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005230.1|refseq:XP_016883779.1|ensembl:ENSG00000157557(gene)|ensembl:ENST00000360214(transcript)|ensembl:ENST00000360938(transcript)|ensembl:ENST00000653642(transcript)|ensembl:ENST00000662305(transcript)|ensembl:ENST00000666778(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001712"(ectodermal cell fate commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090009"(primitive streak formation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:XP_005260992.1|dip:DIP-40452N|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR027276|interpro:IPR036388|interpro:IPR036390|rcsb pdb:4BQA|rcsb pdb:4MHV|reactome:R-HSA-2559585	refseq:NP_000465.1|refseq:XP_011513798.1|dip:DIP-45974N|ensembl:ENSG00000122691(gene)|ensembl:ENST00000242261(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001503"(ossification)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0001843"(neural tube closure)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003183"(mitral valve morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003253"(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0032502"(developmental process)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033128"(negative regulation of histone phosphorylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042476"(odontogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060363"(cranial suture morphogenesis)|go:"GO:0060900"(embryonic camera-type eye formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0070888"(E-box binding)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000276"(negative regulation of oxidative phosphorylation uncoupler activity)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000780"(negative regulation of double-strand break repair)|go:"GO:2000793"(cell proliferation involved in heart valve development)|go:"GO:2000802"(positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015789(Twist)|interpro:IPR036638|rcsb pdb:2MJV|reactome:R-HSA-6785807|reactome:R-HSA-8878166|reactome:R-HSA-8939902	psi-mi:"MI:0469"(intact)	-	-	delivery method:Q15672; P15036 transfection|figure legend:S3 A|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/07/28	2014/10/16	rogid:mHFB3G4Y52dZ3dUM2zbx+vamz9c9606	rogid:1+WEEh0ruAAKCxlJQCVzBqTrhIM9606	intact-crc:9411FB580F544E49|rigid:uyqM6unvSR7qB8UAAx6HlRTwd+M	false	-	flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P15036	uniprotkb:Q8WVJ9	intact:EBI-1646991|uniprotkb:D3DSH6|uniprotkb:A6NM68|uniprotkb:Q53Y89|ensembl:ENSP00000353344|ensembl:ENSP00000354194|ensembl:ENSP00000499226|ensembl:ENSP00000499315|ensembl:ENSP00000499775	intact:EBI-1797313|uniprotkb:Q3SYL6|ensembl:ENSP00000405176|ensembl:ENSP00000482581|ensembl:ENSP00000500440|ensembl:ENSP00000500609	psi-mi:ets2_human(display_long)|uniprotkb:ETS2(gene name)|psi-mi:ETS2(display_short)	psi-mi:twst2_human(display_long)|uniprotkb:Dermis-expressed protein 1(gene name synonym)|uniprotkb:TWIST2(gene name)|psi-mi:TWIST2(display_short)|uniprotkb:DERMO1(gene name synonym)|uniprotkb:BHLHA39(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 39(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ansieau et al. (2008)	imex:IM-12059|pubmed:18598946	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1797327|imex:IM-12059-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005230.1|refseq:XP_016883779.1|ensembl:ENSG00000157557(gene)|ensembl:ENST00000360214(transcript)|ensembl:ENST00000360938(transcript)|ensembl:ENST00000653642(transcript)|ensembl:ENST00000662305(transcript)|ensembl:ENST00000666778(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001712"(ectodermal cell fate commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090009"(primitive streak formation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:XP_005260992.1|dip:DIP-40452N|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR027276|interpro:IPR036388|interpro:IPR036390|rcsb pdb:4BQA|rcsb pdb:4MHV|reactome:R-HSA-2559585	refseq:NP_001258822.1|refseq:NP_476527.1|ensembl:ENSG00000233608(gene)|ensembl:ENSG00000288335(gene)|ensembl:ENST00000448943(transcript)|ensembl:ENST00000612363(transcript)|ensembl:ENST00000671947(transcript)|ensembl:ENST00000673387(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032502"(developmental process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015789(Twist)|interpro:IPR036638|reactome:R-HSA-8878166	psi-mi:"MI:0469"(intact)	-	-	delivery method:Q8WVJ9; P15036 transfection|figure legend:S3 A|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/07/28	2014/10/16	rogid:mHFB3G4Y52dZ3dUM2zbx+vamz9c9606	rogid:IYIpMXYdrqllQqS+Ftz+P0xtk789606	intact-crc:BA1B727BED6DBBD9|rigid:Ryzbf4OzJ+A453phGQe8w1WXJyA	false	-	flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P15036	uniprotkb:Q8WVJ9	intact:EBI-1646991|uniprotkb:D3DSH6|uniprotkb:A6NM68|uniprotkb:Q53Y89|ensembl:ENSP00000353344|ensembl:ENSP00000354194|ensembl:ENSP00000499226|ensembl:ENSP00000499315|ensembl:ENSP00000499775	intact:EBI-1797313|uniprotkb:Q3SYL6|ensembl:ENSP00000405176|ensembl:ENSP00000482581|ensembl:ENSP00000500440|ensembl:ENSP00000500609	psi-mi:ets2_human(display_long)|uniprotkb:ETS2(gene name)|psi-mi:ETS2(display_short)	psi-mi:twst2_human(display_long)|uniprotkb:Dermis-expressed protein 1(gene name synonym)|uniprotkb:TWIST2(gene name)|psi-mi:TWIST2(display_short)|uniprotkb:DERMO1(gene name synonym)|uniprotkb:BHLHA39(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 39(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ansieau et al. (2008)	imex:IM-12059|pubmed:18598946	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1797335|imex:IM-12059-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005230.1|refseq:XP_016883779.1|ensembl:ENSG00000157557(gene)|ensembl:ENST00000360214(transcript)|ensembl:ENST00000360938(transcript)|ensembl:ENST00000653642(transcript)|ensembl:ENST00000662305(transcript)|ensembl:ENST00000666778(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001712"(ectodermal cell fate commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090009"(primitive streak formation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:XP_005260992.1|dip:DIP-40452N|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR027276|interpro:IPR036388|interpro:IPR036390|rcsb pdb:4BQA|rcsb pdb:4MHV|reactome:R-HSA-2559585	refseq:NP_001258822.1|refseq:NP_476527.1|ensembl:ENSG00000233608(gene)|ensembl:ENSG00000288335(gene)|ensembl:ENST00000448943(transcript)|ensembl:ENST00000612363(transcript)|ensembl:ENST00000671947(transcript)|ensembl:ENST00000673387(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032502"(developmental process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015789(Twist)|interpro:IPR036638|reactome:R-HSA-8878166	psi-mi:"MI:0469"(intact)	-	-	delivery method:Q8WVJ9; P15036 transfection|figure legend:S3 B|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/07/28	2014/10/16	rogid:mHFB3G4Y52dZ3dUM2zbx+vamz9c9606	rogid:IYIpMXYdrqllQqS+Ftz+P0xtk789606	intact-crc:87E194907EA4C88E|rigid:Ryzbf4OzJ+A453phGQe8w1WXJyA	false	-	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15672	uniprotkb:P15036	intact:EBI-1797287|uniprotkb:Q92487|uniprotkb:Q99804|uniprotkb:A4D128|ensembl:ENSP00000242261	intact:EBI-1646991|uniprotkb:D3DSH6|uniprotkb:A6NM68|uniprotkb:Q53Y89|ensembl:ENSP00000353344|ensembl:ENSP00000354194|ensembl:ENSP00000499226|ensembl:ENSP00000499315|ensembl:ENSP00000499775	psi-mi:twst1_human(display_long)|uniprotkb:H-twist(gene name synonym)|uniprotkb:TWIST1(gene name)|psi-mi:TWIST1(display_short)|uniprotkb:TWIST(gene name synonym)|uniprotkb:BHLHA38(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 38(gene name synonym)	psi-mi:ets2_human(display_long)|uniprotkb:ETS2(gene name)|psi-mi:ETS2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ansieau et al. (2008)	imex:IM-12059|pubmed:18598946	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1797350|imex:IM-12059-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000465.1|refseq:XP_011513798.1|dip:DIP-45974N|ensembl:ENSG00000122691(gene)|ensembl:ENST00000242261(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001503"(ossification)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0001843"(neural tube closure)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003183"(mitral valve morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003253"(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0032502"(developmental process)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033128"(negative regulation of histone phosphorylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042476"(odontogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060363"(cranial suture morphogenesis)|go:"GO:0060900"(embryonic camera-type eye formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0070888"(E-box binding)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000276"(negative regulation of oxidative phosphorylation uncoupler activity)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000780"(negative regulation of double-strand break repair)|go:"GO:2000793"(cell proliferation involved in heart valve development)|go:"GO:2000802"(positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015789(Twist)|interpro:IPR036638|rcsb pdb:2MJV|reactome:R-HSA-6785807|reactome:R-HSA-8878166|reactome:R-HSA-8939902	refseq:NP_005230.1|refseq:XP_016883779.1|ensembl:ENSG00000157557(gene)|ensembl:ENST00000360214(transcript)|ensembl:ENST00000360938(transcript)|ensembl:ENST00000653642(transcript)|ensembl:ENST00000662305(transcript)|ensembl:ENST00000666778(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001712"(ectodermal cell fate commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090009"(primitive streak formation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:XP_005260992.1|dip:DIP-40452N|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR027276|interpro:IPR036388|interpro:IPR036390|rcsb pdb:4BQA|rcsb pdb:4MHV|reactome:R-HSA-2559585	psi-mi:"MI:0469"(intact)	-	-	delivery method:Q15672; P15036 transfection|figure legend:S3 B|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/07/28	2014/10/16	rogid:1+WEEh0ruAAKCxlJQCVzBqTrhIM9606	rogid:mHFB3G4Y52dZ3dUM2zbx+vamz9c9606	intact-crc:07E4246A2A13745F|rigid:uyqM6unvSR7qB8UAAx6HlRTwd+M	false	flag tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)