#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8IU99	uniprotkb:Q8IU99	intact:EBI-1790341|uniprotkb:Q5W091|ensembl:ENSP00000329926	intact:EBI-1790341|uniprotkb:Q5W091|ensembl:ENSP00000329926	psi-mi:cahm1_human(display_long)|uniprotkb:FAM26C(gene name synonym)|uniprotkb:Protein FAM26C(gene name synonym)|uniprotkb:CALHM1(gene name)|psi-mi:CALHM1(display_short)	psi-mi:cahm1_human(display_long)|uniprotkb:FAM26C(gene name synonym)|uniprotkb:Protein FAM26C(gene name synonym)|uniprotkb:CALHM1(gene name)|psi-mi:CALHM1(display_short)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Dreses-Werringloer et al. (2008)	imex:IM-11925|pubmed:18585350	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1790360|imex:IM-11925-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001412.3|ensembl:ENSG00000185933(gene)|ensembl:ENST00000329905(transcript)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0015867"(ATP transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0050896"(response to stimulus)|go:"GO:0050913"(sensory perception of bitter taste)|go:"GO:0050916"(sensory perception of sweet taste)|go:"GO:0050917"(sensory perception of umami taste)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051291"(protein heterooligomerization)|interpro:IPR029568|interpro:IPR029569	refseq:NP_001001412.3|ensembl:ENSG00000185933(gene)|ensembl:ENST00000329905(transcript)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0015867"(ATP transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0050896"(response to stimulus)|go:"GO:0050913"(sensory perception of bitter taste)|go:"GO:0050916"(sensory perception of sweet taste)|go:"GO:0050917"(sensory perception of umami taste)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051291"(protein heterooligomerization)|interpro:IPR029568|interpro:IPR029569	go:"GO:0043621"(protein self-association)	-	-	figure legend:Figure 4A|comment:Dimer formation determined by molecular weight|delivery method:Q8IU99 transfection|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/07/10	2014/10/16	rogid:WY6DtfwGz0ejISG2zTNqZUuDh8A9606	rogid:WY6DtfwGz0ejISG2zTNqZUuDh8A9606	intact-crc:31A99E0ED78CC422|rigid:69BcPFkl4lMBcyOIGbOHhk5/4To	false	myc tag:c-c	myc tag:c-c	2	0	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8IU99	uniprotkb:Q8IU99	intact:EBI-1790341|uniprotkb:Q5W091|ensembl:ENSP00000329926	intact:EBI-1790341|uniprotkb:Q5W091|ensembl:ENSP00000329926	psi-mi:cahm1_human(display_long)|uniprotkb:FAM26C(gene name synonym)|uniprotkb:Protein FAM26C(gene name synonym)|uniprotkb:CALHM1(gene name)|psi-mi:CALHM1(display_short)	psi-mi:cahm1_human(display_long)|uniprotkb:FAM26C(gene name synonym)|uniprotkb:Protein FAM26C(gene name synonym)|uniprotkb:CALHM1(gene name)|psi-mi:CALHM1(display_short)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Dreses-Werringloer et al. (2008)	imex:IM-11925|pubmed:18585350	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1790368|imex:IM-11925-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001412.3|ensembl:ENSG00000185933(gene)|ensembl:ENST00000329905(transcript)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0015867"(ATP transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0050896"(response to stimulus)|go:"GO:0050913"(sensory perception of bitter taste)|go:"GO:0050916"(sensory perception of sweet taste)|go:"GO:0050917"(sensory perception of umami taste)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051291"(protein heterooligomerization)|interpro:IPR029568|interpro:IPR029569	refseq:NP_001001412.3|ensembl:ENSG00000185933(gene)|ensembl:ENST00000329905(transcript)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0015867"(ATP transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0050896"(response to stimulus)|go:"GO:0050913"(sensory perception of bitter taste)|go:"GO:0050916"(sensory perception of sweet taste)|go:"GO:0050917"(sensory perception of umami taste)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051291"(protein heterooligomerization)|interpro:IPR029568|interpro:IPR029569	go:"GO:0043621"(protein self-association)	-	-	figure legend:Figure 4A|comment:Tetramer formation determined by molecular weight|delivery method:Q8IU99 transfection|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/07/10	2014/10/16	rogid:WY6DtfwGz0ejISG2zTNqZUuDh8A9606	rogid:WY6DtfwGz0ejISG2zTNqZUuDh8A9606	intact-crc:54F35C795F6822C9|rigid:69BcPFkl4lMBcyOIGbOHhk5/4To	false	myc tag:c-c	myc tag:c-c	4	0	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8IU99	uniprotkb:Q8IU99	intact:EBI-1790341|uniprotkb:Q5W091|ensembl:ENSP00000329926	intact:EBI-1790341|uniprotkb:Q5W091|ensembl:ENSP00000329926	psi-mi:cahm1_human(display_long)|uniprotkb:FAM26C(gene name synonym)|uniprotkb:Protein FAM26C(gene name synonym)|uniprotkb:CALHM1(gene name)|psi-mi:CALHM1(display_short)	psi-mi:cahm1_human(display_long)|uniprotkb:FAM26C(gene name synonym)|uniprotkb:Protein FAM26C(gene name synonym)|uniprotkb:CALHM1(gene name)|psi-mi:CALHM1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Dreses-Werringloer et al. (2008)	imex:IM-11925|pubmed:18585350	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1790392|imex:IM-11925-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001412.3|ensembl:ENSG00000185933(gene)|ensembl:ENST00000329905(transcript)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0015867"(ATP transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0050896"(response to stimulus)|go:"GO:0050913"(sensory perception of bitter taste)|go:"GO:0050916"(sensory perception of sweet taste)|go:"GO:0050917"(sensory perception of umami taste)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051291"(protein heterooligomerization)|interpro:IPR029568|interpro:IPR029569	refseq:NP_001001412.3|ensembl:ENSG00000185933(gene)|ensembl:ENST00000329905(transcript)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0015867"(ATP transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0050896"(response to stimulus)|go:"GO:0050913"(sensory perception of bitter taste)|go:"GO:0050916"(sensory perception of sweet taste)|go:"GO:0050917"(sensory perception of umami taste)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051291"(protein heterooligomerization)|interpro:IPR029568|interpro:IPR029569	go:"GO:0042802"(identical protein binding)	-	-	figure legend:Figure 4B|delivery method:Q8IU99 transfection|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/07/10	2014/10/16	rogid:WY6DtfwGz0ejISG2zTNqZUuDh8A9606	rogid:WY6DtfwGz0ejISG2zTNqZUuDh8A9606	intact-crc:44629A080E75F1B2|rigid:2Rgf1bHpeh9+Xz6Pk3INltri9+k	false	v5 tag:c-c	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)