#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P49333 uniprotkb:Q38846 intact:EBI-1606682|ensemblplants:AT1G66340.1 intact:EBI-1606754|ensemblplants:AT2G40940.1 psi-mi:etr1_arath(display_long)|uniprotkb:ETR1(gene name)|psi-mi:ETR1(display_short)|uniprotkb:T27F4.9(orf name)|uniprotkb:At1g66340(locus name)|uniprotkb:Protein ETHYLENE RESPONSE 1(gene name synonym)|uniprotkb:Protein ETR1(gene name synonym) psi-mi:ers1_arath(display_long)|uniprotkb:ERS1(gene name)|psi-mi:ERS1(display_short)|uniprotkb:ERS(gene name synonym)|uniprotkb:At2g40940(locus name)|uniprotkb:Protein ERS1(gene name synonym)|uniprotkb:T20B5.14(orf name) psi-mi:"MI:0676"(tandem affinity purification) Gao et al. (2008) pubmed:18577522|imex:IM-19036 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1787526|imex:IM-19036-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4PL9|refseq:NP_176808.3|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011006(CheY-like)|interpro:IPR003018(GAF)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR014525(Signal transduction histidine kinase, hybrid-type, ethylene sensor)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR001789(Signal transduction response regulator, receiver region)|rcsb pdb:1DCF|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009739"(response to gibberellin)|go:"GO:0010087"(phloem or xylem histogenesis)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0010119"(regulation of stomatal movement)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0051740"(ethylene binding)|go:"GO:0052544"(defense response by callose deposition in cell wall)|go:"GO:1900140"(regulation of seedling development)|interpro:IPR029016|ensemblplants:AT1G66340(gene)|ensemblplants:AT1G66340.1(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0009408"(response to heat)|go:"GO:0009625"(response to insect)|go:"GO:0009651"(response to salt stress)|go:"GO:0009690"(cytokinin metabolic process)|go:"GO:0009723"(response to ethylene)|go:"GO:0009727"(detection of ethylene stimulus)|go:"GO:0009733"(response to auxin)|interpro:IPR036097|interpro:IPR036890 refseq:NP_181626.1|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003018(GAF)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|rcsb pdb:4MT8|rcsb pdb:4MTX|ensemblplants:AT2G40940(gene)|interpro:IPR029016|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051740"(ethylene binding)|ensemblplants:AT2G40940.1(transcript)|interpro:IPR036097|interpro:IPR036890 - - - figure legend:Figure 2 Figure 3B Figure 3C|agonist:Ethylene.|comment:"The authors stated \"the total amount of ETR1 associated with ERS1-TAP also showed a small increase following the short-term ethylene treatment\" but a \"longer-term ethylene treatment of the ERS1-TAP line resulted in a total level of ETR1 association with ERS1-TAP coincident with the increase in ERS1-TAP levels\"."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") - 2008/07/02 2014/10/16 rogid:HU7HG7EHvZR/6trEt2M2wmFdHRY3702 rogid:YWQgcm36eoN4fz7TlLzn4LP7Uts3702 intact-crc:7602257048D624C0|rigid:8G2elR3QslKA51506ztodXhwS+Y false - calmodulin binding peptide plus protein a tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q0WPQ2 uniprotkb:P49333 intact:EBI-1787533|uniprotkb:Q9LTD5|uniprotkb:O82429|intact:EBI-2314631|ensemblplants:AT3G23150.1 intact:EBI-1606682|ensemblplants:AT1G66340.1 psi-mi:etr2_arath(display_long)|uniprotkb:ETR2(gene name)|psi-mi:ETR2(display_short)|uniprotkb:Protein ETHYLENE RESPONSE 2(gene name synonym)|uniprotkb:Protein ETR2(gene name synonym)|uniprotkb:K14B15.9(orf name)|uniprotkb:At3g23150(locus name) psi-mi:etr1_arath(display_long)|uniprotkb:ETR1(gene name)|psi-mi:ETR1(display_short)|uniprotkb:T27F4.9(orf name)|uniprotkb:At1g66340(locus name)|uniprotkb:Protein ETHYLENE RESPONSE 1(gene name synonym)|uniprotkb:Protein ETR1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Gao et al. (2008) pubmed:18577522|imex:IM-19036 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1787549|imex:IM-19036-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_188956.1|interpro:IPR011006(CheY-like)|interpro:IPR003018(GAF)|interpro:IPR014525(Signal transduction histidine kinase, hybrid-type, ethylene sensor)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR029016|refseq:NP_001326955.1|interpro:IPR036097|interpro:IPR036890|ensemblplants:AT3G23150(gene)|ensemblplants:AT3G23150.1(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051740"(ethylene binding)|go:"GO:0071456"(cellular response to hypoxia) rcsb pdb:4PL9|refseq:NP_176808.3|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011006(CheY-like)|interpro:IPR003018(GAF)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR014525(Signal transduction histidine kinase, hybrid-type, ethylene sensor)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR001789(Signal transduction response regulator, receiver region)|rcsb pdb:1DCF|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009739"(response to gibberellin)|go:"GO:0010087"(phloem or xylem histogenesis)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0010119"(regulation of stomatal movement)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0051740"(ethylene binding)|go:"GO:0052544"(defense response by callose deposition in cell wall)|go:"GO:1900140"(regulation of seedling development)|interpro:IPR029016|ensemblplants:AT1G66340(gene)|ensemblplants:AT1G66340.1(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0009408"(response to heat)|go:"GO:0009625"(response to insect)|go:"GO:0009651"(response to salt stress)|go:"GO:0009690"(cytokinin metabolic process)|go:"GO:0009723"(response to ethylene)|go:"GO:0009727"(detection of ethylene stimulus)|go:"GO:0009733"(response to auxin)|interpro:IPR036097|interpro:IPR036890 - - - figure legend:Figure 2 Figure 3A|agonist:Ethylene. A 4-hr treatment with 10 uL/L ethylene.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") - 2008/07/02 2014/10/16 rogid:KovXEnr0Gw06pBZlmQBY70Eb2Cc3702 rogid:HU7HG7EHvZR/6trEt2M2wmFdHRY3702 intact-crc:70BDA1AB65AB286E|rigid:Mp4Y2RQfjrAfrUP//+Dfk9QkgfA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P93825 uniprotkb:P49333 intact:EBI-1787556|uniprotkb:B0FVU3|uniprotkb:B0FVU5|uniprotkb:B0FVW8|uniprotkb:B0FVX0|uniprotkb:B0FVX9|ensemblplants:AT1G04310.1|ensemblplants:AT1G04310.2 intact:EBI-1606682|ensemblplants:AT1G66340.1 psi-mi:ers2_arath(display_long)|uniprotkb:ERS2(gene name)|psi-mi:ERS2(display_short)|uniprotkb:F19P19.25(orf name)|uniprotkb:At1g04310(locus name)|uniprotkb:Protein ERS2(gene name synonym) psi-mi:etr1_arath(display_long)|uniprotkb:ETR1(gene name)|psi-mi:ETR1(display_short)|uniprotkb:T27F4.9(orf name)|uniprotkb:At1g66340(locus name)|uniprotkb:Protein ETHYLENE RESPONSE 1(gene name synonym)|uniprotkb:Protein ETR1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Gao et al. (2008) pubmed:18577522|imex:IM-19036 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1787568|imex:IM-19036-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_171927.1|interpro:IPR003018(GAF)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR029016|refseq:NP_001323287.1|interpro:IPR036097|ensemblplants:AT1G04310(gene)|ensemblplants:AT1G04310.1(transcript)|ensemblplants:AT1G04310.2(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051740"(ethylene binding) rcsb pdb:4PL9|refseq:NP_176808.3|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011006(CheY-like)|interpro:IPR003018(GAF)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR014525(Signal transduction histidine kinase, hybrid-type, ethylene sensor)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR001789(Signal transduction response regulator, receiver region)|rcsb pdb:1DCF|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009739"(response to gibberellin)|go:"GO:0010087"(phloem or xylem histogenesis)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0010119"(regulation of stomatal movement)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0051740"(ethylene binding)|go:"GO:0052544"(defense response by callose deposition in cell wall)|go:"GO:1900140"(regulation of seedling development)|interpro:IPR029016|ensemblplants:AT1G66340(gene)|ensemblplants:AT1G66340.1(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0009408"(response to heat)|go:"GO:0009625"(response to insect)|go:"GO:0009651"(response to salt stress)|go:"GO:0009690"(cytokinin metabolic process)|go:"GO:0009723"(response to ethylene)|go:"GO:0009727"(detection of ethylene stimulus)|go:"GO:0009733"(response to auxin)|interpro:IPR036097|interpro:IPR036890 - - - figure legend:Figure 2 Figure 3B Figure 3C Figure 5|antagonist:Ethylene. A 4-hr treatment with 10 uL/L ethylene.|inhibition:"SDS (sodium dodecyl sulfate). Elution of bound complex from binding matrix with with 1% SDS reduced copurification of proteins by 80%."|inhibition:"DTT (1,4-Dithioerythritol)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") - 2008/07/02 2014/10/16 rogid:d4ieLgKuaKMJj44oy0aBa9nzbYU3702 rogid:HU7HG7EHvZR/6trEt2M2wmFdHRY3702 intact-crc:C6B2097A7142EB57|rigid:UheFSp8tPKBwZ4tJesIHvWBKZ7A false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49333 uniprotkb:Q9ZTP3 intact:EBI-1606682|ensemblplants:AT1G66340.1 intact:EBI-1787575|ensemblplants:AT3G04580.1|ensemblplants:AT3G04580.2 psi-mi:etr1_arath(display_long)|uniprotkb:ETR1(gene name)|psi-mi:ETR1(display_short)|uniprotkb:T27F4.9(orf name)|uniprotkb:At1g66340(locus name)|uniprotkb:Protein ETHYLENE RESPONSE 1(gene name synonym)|uniprotkb:Protein ETR1(gene name synonym) psi-mi:ein4_arath(display_long)|uniprotkb:EIN4(gene name)|psi-mi:EIN4(display_short)|uniprotkb:Protein ETHYLENE INSENSITIVE 4(gene name synonym)|uniprotkb:At3g04580(locus name)|uniprotkb:F7O18.5(orf name) psi-mi:"MI:0676"(tandem affinity purification) Gao et al. (2008) pubmed:18577522|imex:IM-19036 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1787587|imex:IM-19036-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4PL9|refseq:NP_176808.3|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011006(CheY-like)|interpro:IPR003018(GAF)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR014525(Signal transduction histidine kinase, hybrid-type, ethylene sensor)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR001789(Signal transduction response regulator, receiver region)|rcsb pdb:1DCF|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009739"(response to gibberellin)|go:"GO:0010087"(phloem or xylem histogenesis)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0010119"(regulation of stomatal movement)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0051740"(ethylene binding)|go:"GO:0052544"(defense response by callose deposition in cell wall)|go:"GO:1900140"(regulation of seedling development)|interpro:IPR029016|ensemblplants:AT1G66340(gene)|ensemblplants:AT1G66340.1(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0009408"(response to heat)|go:"GO:0009625"(response to insect)|go:"GO:0009651"(response to salt stress)|go:"GO:0009690"(cytokinin metabolic process)|go:"GO:0009723"(response to ethylene)|go:"GO:0009727"(detection of ethylene stimulus)|go:"GO:0009733"(response to auxin)|interpro:IPR036097|interpro:IPR036890 refseq:NP_187108.1|refseq:NP_974218.1|interpro:IPR011006(CheY-like)|interpro:IPR003018(GAF)|interpro:IPR014525(Signal transduction histidine kinase, hybrid-type, ethylene sensor)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR029016|interpro:IPR036097|interpro:IPR036890|ensemblplants:AT3G04580(gene)|ensemblplants:AT3G04580.1(transcript)|ensemblplants:AT3G04580.2(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051740"(ethylene binding) - - - figure legend:Figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") - 2008/07/02 2014/10/16 rogid:HU7HG7EHvZR/6trEt2M2wmFdHRY3702 rogid:hC2uiUoAe2r5LigEvVYQ90bsuCU3702 intact-crc:F75B1B6DEC5B0776|rigid:hib8JPofwlFLLcMBkRSBvflAbHI false - calmodulin binding peptide plus protein a tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P93825 uniprotkb:P93825 intact:EBI-1787556|uniprotkb:B0FVU3|uniprotkb:B0FVU5|uniprotkb:B0FVW8|uniprotkb:B0FVX0|uniprotkb:B0FVX9|ensemblplants:AT1G04310.1|ensemblplants:AT1G04310.2 intact:EBI-1787556|uniprotkb:B0FVU3|uniprotkb:B0FVU5|uniprotkb:B0FVW8|uniprotkb:B0FVX0|uniprotkb:B0FVX9|ensemblplants:AT1G04310.1|ensemblplants:AT1G04310.2 psi-mi:ers2_arath(display_long)|uniprotkb:ERS2(gene name)|psi-mi:ERS2(display_short)|uniprotkb:F19P19.25(orf name)|uniprotkb:At1g04310(locus name)|uniprotkb:Protein ERS2(gene name synonym) psi-mi:ers2_arath(display_long)|uniprotkb:ERS2(gene name)|psi-mi:ERS2(display_short)|uniprotkb:F19P19.25(orf name)|uniprotkb:At1g04310(locus name)|uniprotkb:Protein ERS2(gene name synonym) psi-mi:"MI:0807"(comigration in gel electrophoresis) Gao et al. (2008) pubmed:18577522|imex:IM-19036 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1787671|imex:IM-19036-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_171927.1|interpro:IPR003018(GAF)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR029016|refseq:NP_001323287.1|interpro:IPR036097|ensemblplants:AT1G04310(gene)|ensemblplants:AT1G04310.1(transcript)|ensemblplants:AT1G04310.2(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051740"(ethylene binding) refseq:NP_171927.1|interpro:IPR003018(GAF)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR029016|refseq:NP_001323287.1|interpro:IPR036097|ensemblplants:AT1G04310(gene)|ensemblplants:AT1G04310.1(transcript)|ensemblplants:AT1G04310.2(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051740"(ethylene binding) go:"GO:0042803"(protein homodimerization activity) - - figure legend:Figure 4|comment:"The authors noted that in \"the absence of reducing reagent, both ERS2 (1-356)- GST and ETR1-TAP were found to form homodimers when expressed individually\"."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/02 2014/10/16 rogid:d4ieLgKuaKMJj44oy0aBa9nzbYU3702 rogid:d4ieLgKuaKMJj44oy0aBa9nzbYU3702 intact-crc:3E005F92964A0976|rigid:Zr5G2IxlilBq/QKD0dR5xoyfQJ0 false glutathione s tranferase tag:c-c|sufficient binding region:1-356 glutathione s tranferase tag:c-c|sufficient binding region:1-356 2 0 psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P49333 uniprotkb:P93825 intact:EBI-1606682|ensemblplants:AT1G66340.1 intact:EBI-1787556|uniprotkb:B0FVU3|uniprotkb:B0FVU5|uniprotkb:B0FVW8|uniprotkb:B0FVX0|uniprotkb:B0FVX9|ensemblplants:AT1G04310.1|ensemblplants:AT1G04310.2 psi-mi:etr1_arath(display_long)|uniprotkb:ETR1(gene name)|psi-mi:ETR1(display_short)|uniprotkb:T27F4.9(orf name)|uniprotkb:At1g66340(locus name)|uniprotkb:Protein ETHYLENE RESPONSE 1(gene name synonym)|uniprotkb:Protein ETR1(gene name synonym) psi-mi:ers2_arath(display_long)|uniprotkb:ERS2(gene name)|psi-mi:ERS2(display_short)|uniprotkb:F19P19.25(orf name)|uniprotkb:At1g04310(locus name)|uniprotkb:Protein ERS2(gene name synonym) psi-mi:"MI:0807"(comigration in gel electrophoresis) Gao et al. (2008) pubmed:18577522|imex:IM-19036 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1787683|imex:IM-19036-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4PL9|refseq:NP_176808.3|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011006(CheY-like)|interpro:IPR003018(GAF)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR014525(Signal transduction histidine kinase, hybrid-type, ethylene sensor)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR001789(Signal transduction response regulator, receiver region)|rcsb pdb:1DCF|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009739"(response to gibberellin)|go:"GO:0010087"(phloem or xylem histogenesis)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0010119"(regulation of stomatal movement)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0051740"(ethylene binding)|go:"GO:0052544"(defense response by callose deposition in cell wall)|go:"GO:1900140"(regulation of seedling development)|interpro:IPR029016|ensemblplants:AT1G66340(gene)|ensemblplants:AT1G66340.1(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0009408"(response to heat)|go:"GO:0009625"(response to insect)|go:"GO:0009651"(response to salt stress)|go:"GO:0009690"(cytokinin metabolic process)|go:"GO:0009723"(response to ethylene)|go:"GO:0009727"(detection of ethylene stimulus)|go:"GO:0009733"(response to auxin)|interpro:IPR036097|interpro:IPR036890 refseq:NP_171927.1|interpro:IPR003018(GAF)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR029016|refseq:NP_001323287.1|interpro:IPR036097|ensemblplants:AT1G04310(gene)|ensemblplants:AT1G04310.1(transcript)|ensemblplants:AT1G04310.2(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051740"(ethylene binding) - - - figure legend:Figure 4|comment:"The authors noted that this heterodimer was only observed \"in the absence of reducing reagent\"."|caution:As the detection method used an antibody which cross-reacted with both TAP and GST tags the authors assume by analysis of complex size that this protein complex is a heterodimer of ERS2 and ETR1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/02 2014/10/16 rogid:HU7HG7EHvZR/6trEt2M2wmFdHRY3702 rogid:d4ieLgKuaKMJj44oy0aBa9nzbYU3702 intact-crc:B200484F05528608|rigid:UheFSp8tPKBwZ4tJesIHvWBKZ7A false glutathione s tranferase tag:c-c calmodulin binding peptide plus protein a tag:c-c|sufficient binding region:1-356 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P49333 uniprotkb:P49333 intact:EBI-1606682|ensemblplants:AT1G66340.1 intact:EBI-1606682|ensemblplants:AT1G66340.1 psi-mi:etr1_arath(display_long)|uniprotkb:ETR1(gene name)|psi-mi:ETR1(display_short)|uniprotkb:T27F4.9(orf name)|uniprotkb:At1g66340(locus name)|uniprotkb:Protein ETHYLENE RESPONSE 1(gene name synonym)|uniprotkb:Protein ETR1(gene name synonym) psi-mi:etr1_arath(display_long)|uniprotkb:ETR1(gene name)|psi-mi:ETR1(display_short)|uniprotkb:T27F4.9(orf name)|uniprotkb:At1g66340(locus name)|uniprotkb:Protein ETHYLENE RESPONSE 1(gene name synonym)|uniprotkb:Protein ETR1(gene name synonym) psi-mi:"MI:0807"(comigration in gel electrophoresis) Gao et al. (2008) pubmed:18577522|imex:IM-19036 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1787694|imex:IM-19036-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4PL9|refseq:NP_176808.3|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011006(CheY-like)|interpro:IPR003018(GAF)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR014525(Signal transduction histidine kinase, hybrid-type, ethylene sensor)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR001789(Signal transduction response regulator, receiver region)|rcsb pdb:1DCF|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009739"(response to gibberellin)|go:"GO:0010087"(phloem or xylem histogenesis)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0010119"(regulation of stomatal movement)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0051740"(ethylene binding)|go:"GO:0052544"(defense response by callose deposition in cell wall)|go:"GO:1900140"(regulation of seedling development)|interpro:IPR029016|ensemblplants:AT1G66340(gene)|ensemblplants:AT1G66340.1(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0009408"(response to heat)|go:"GO:0009625"(response to insect)|go:"GO:0009651"(response to salt stress)|go:"GO:0009690"(cytokinin metabolic process)|go:"GO:0009723"(response to ethylene)|go:"GO:0009727"(detection of ethylene stimulus)|go:"GO:0009733"(response to auxin)|interpro:IPR036097|interpro:IPR036890 rcsb pdb:4PL9|refseq:NP_176808.3|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011006(CheY-like)|interpro:IPR003018(GAF)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR014525(Signal transduction histidine kinase, hybrid-type, ethylene sensor)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR001789(Signal transduction response regulator, receiver region)|rcsb pdb:1DCF|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009739"(response to gibberellin)|go:"GO:0010087"(phloem or xylem histogenesis)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0010119"(regulation of stomatal movement)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0051740"(ethylene binding)|go:"GO:0052544"(defense response by callose deposition in cell wall)|go:"GO:1900140"(regulation of seedling development)|interpro:IPR029016|ensemblplants:AT1G66340(gene)|ensemblplants:AT1G66340.1(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0009408"(response to heat)|go:"GO:0009625"(response to insect)|go:"GO:0009651"(response to salt stress)|go:"GO:0009690"(cytokinin metabolic process)|go:"GO:0009723"(response to ethylene)|go:"GO:0009727"(detection of ethylene stimulus)|go:"GO:0009733"(response to auxin)|interpro:IPR036097|interpro:IPR036890 go:"GO:0042803"(protein homodimerization activity) - - figure legend:Figure 4|comment:The authors noted that the homodimer was only observed in the absence of reducing reagent.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/02 2014/10/16 rogid:HU7HG7EHvZR/6trEt2M2wmFdHRY3702 rogid:HU7HG7EHvZR/6trEt2M2wmFdHRY3702 intact-crc:CEF018B99933C415|rigid:wGUreWx2fipq0hbJEogOCszTSCA false calmodulin binding peptide plus protein a tag:c-c calmodulin binding peptide plus protein a tag:c-c 2 0 psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q0WPQ2 uniprotkb:P49333 intact:EBI-1787533|uniprotkb:Q9LTD5|uniprotkb:O82429|intact:EBI-2314631|ensemblplants:AT3G23150.1 intact:EBI-1606682|ensemblplants:AT1G66340.1 psi-mi:etr2_arath(display_long)|uniprotkb:ETR2(gene name)|psi-mi:ETR2(display_short)|uniprotkb:Protein ETHYLENE RESPONSE 2(gene name synonym)|uniprotkb:Protein ETR2(gene name synonym)|uniprotkb:K14B15.9(orf name)|uniprotkb:At3g23150(locus name) psi-mi:etr1_arath(display_long)|uniprotkb:ETR1(gene name)|psi-mi:ETR1(display_short)|uniprotkb:T27F4.9(orf name)|uniprotkb:At1g66340(locus name)|uniprotkb:Protein ETHYLENE RESPONSE 1(gene name synonym)|uniprotkb:Protein ETR1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18577522|imex:IM-19036 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1787715|imex:IM-19036-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_188956.1|interpro:IPR011006(CheY-like)|interpro:IPR003018(GAF)|interpro:IPR014525(Signal transduction histidine kinase, hybrid-type, ethylene sensor)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR029016|refseq:NP_001326955.1|interpro:IPR036097|interpro:IPR036890|ensemblplants:AT3G23150(gene)|ensemblplants:AT3G23150.1(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051740"(ethylene binding)|go:"GO:0071456"(cellular response to hypoxia) rcsb pdb:4PL9|refseq:NP_176808.3|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011006(CheY-like)|interpro:IPR003018(GAF)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR014525(Signal transduction histidine kinase, hybrid-type, ethylene sensor)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR001789(Signal transduction response regulator, receiver region)|rcsb pdb:1DCF|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009739"(response to gibberellin)|go:"GO:0010087"(phloem or xylem histogenesis)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0010119"(regulation of stomatal movement)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0051740"(ethylene binding)|go:"GO:0052544"(defense response by callose deposition in cell wall)|go:"GO:1900140"(regulation of seedling development)|interpro:IPR029016|ensemblplants:AT1G66340(gene)|ensemblplants:AT1G66340.1(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0009408"(response to heat)|go:"GO:0009625"(response to insect)|go:"GO:0009651"(response to salt stress)|go:"GO:0009690"(cytokinin metabolic process)|go:"GO:0009723"(response to ethylene)|go:"GO:0009727"(detection of ethylene stimulus)|go:"GO:0009733"(response to auxin)|interpro:IPR036097|interpro:IPR036890 - - - figure legend:Figure 6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/02 2014/10/16 rogid:KovXEnr0Gw06pBZlmQBY70Eb2Cc3702 rogid:HU7HG7EHvZR/6trEt2M2wmFdHRY3702 intact-crc:50D1C0E11E6E248F|rigid:Mp4Y2RQfjrAfrUP//+Dfk9QkgfA false sufficient binding region:143-381(IPR003018) sufficient binding region:129-330(IPR003018) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)