#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P68451	uniprotkb:P68451	intact:EBI-7066119|uniprotkb:P21091|intact:MINT-6629061	intact:EBI-7066119|uniprotkb:P21091|intact:MINT-6629061	psi-mi:f1_vaccp(display_long)|uniprotkb:F1L(orf name)	psi-mi:f1_vaccp(display_long)|uniprotkb:F1L(orf name)	psi-mi:"MI:0028"(cosedimentation in solution)	Kvansakul et al. (2008)	pubmed:18551131|mint:MINT-6629173|doi:10.1038/cdd.2008.83	taxid:31531(vaccp)|taxid:31531("Vaccinia virus (strain L-IVP) (VACV)")	taxid:31531(vaccp)|taxid:31531("Vaccinia virus (strain L-IVP) (VACV)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7973609|mint:MINT-6629178	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P68451|go:"GO:0019050"(suppression by virus of host apoptotic process)|interpro:IPR021119|interpro:IPR011207(Uncharacterized conserved protein UCP015971, VAC-F1L)|interpro:IPR036834|mint:MINT-6629179(identity)|uniprotkb:P68451(P68451)	mint:P68451|go:"GO:0019050"(suppression by virus of host apoptotic process)|interpro:IPR021119|interpro:IPR011207(Uncharacterized conserved protein UCP015971, VAC-F1L)|interpro:IPR036834|mint:MINT-6629181(identity)|uniprotkb:P68451(P68451)	-	comment:"fragmentation type: fragment"|comment:mint	comment:"fragmentation type: fragment"|comment:mint	figure legend:T1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/26	2014/10/16	rogid:8/tlI/TrxzhDdoIWa9PQpYrcPMA31531	rogid:8/tlI/TrxzhDdoIWa9PQpYrcPMA31531	intact-crc:BA77315F596CC151|rigid:+YGR5Uv79Qwq4zHRhh/jUSdktSw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P68451	uniprotkb:Q92934	intact:EBI-7066119|uniprotkb:P21091|intact:MINT-6629061	intact:EBI-700771|uniprotkb:O14803|uniprotkb:Q6FH21|ensembl:ENSP00000309103|ensembl:ENSP00000378040	psi-mi:f1_vaccp(display_long)|uniprotkb:F1L(orf name)	psi-mi:bad_human(display_long)|uniprotkb:Bcl-2-binding component 6(gene name synonym)|uniprotkb:Bcl-2-like protein 8(gene name synonym)|uniprotkb:BAD(gene name)|psi-mi:BAD(display_short)|uniprotkb:BBC6(gene name synonym)|uniprotkb:BCL2L8(gene name synonym)|uniprotkb:Bcl-xL/Bcl-2-associated death promoter(gene name synonym)|uniprotkb:Bcl2 antagonist of cell death(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kvansakul et al. (2008)	pubmed:18551131|mint:MINT-6629173|doi:10.1038/cdd.2008.83	taxid:31531(vaccp)|taxid:31531("Vaccinia virus (strain L-IVP) (VACV)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7973648|mint:MINT-6629185	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P68451|go:"GO:0019050"(suppression by virus of host apoptotic process)|interpro:IPR021119|interpro:IPR011207(Uncharacterized conserved protein UCP015971, VAC-F1L)|interpro:IPR036834|mint:MINT-6629186(identity)|uniprotkb:P68451(P68451)	refseq:NP_004313.1|refseq:NP_116784.1|dip:DIP-29184N|ensembl:ENSG00000002330(gene)|ensembl:ENST00000309032(transcript)|ensembl:ENST00000394532(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006007"(glucose catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008289"(lipid binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0009749"(response to glucose)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0033574"(response to testosterone)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044342"(type B pancreatic cell proliferation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046031"(ADP metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060139"(positive regulation of apoptotic process by virus)|go:"GO:0071247"(cellular response to chromate)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901423"(response to benzene)|go:"GO:1902220"(positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1904710"(positive regulation of granulosa cell apoptotic process)|go:"GO:2000078"(positive regulation of type B pancreatic cell development)|interpro:IPR018868|mint:Q92934|rcsb pdb:1G5J|reactome:R-HSA-111447|reactome:R-HSA-111453|reactome:R-HSA-193648|reactome:R-HSA-198323|reactome:R-HSA-5674400|mint:MINT-6629189(identity)|uniprotkb:Q92934(Q92934)	-	comment:"fragmentation type: fragment"|comment:mint	-	figure legend:F3 SF1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/26	2014/10/16	rogid:8/tlI/TrxzhDdoIWa9PQpYrcPMA31531	rogid:2c2kSu+3ZHnx458SDbvIcdGV4PA9606	intact-crc:0554DC972DC7CAEC|rigid:biqJbW3U424IJ5z+DiKZDQXZHpw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P68451	uniprotkb:O43521	intact:EBI-7066119|uniprotkb:P21091|intact:MINT-6629061	intact:EBI-526406|uniprotkb:Q0MSE7|uniprotkb:Q0MSE8|uniprotkb:Q0MSE9|uniprotkb:Q53R28|uniprotkb:Q6JTU6|uniprotkb:Q6T851|uniprotkb:Q6TE14|uniprotkb:Q6TE15|uniprotkb:Q6TE16|uniprotkb:Q6V402|uniprotkb:A8K2W2|uniprotkb:Q8WYL6|uniprotkb:Q8WYL7|uniprotkb:Q8WYL8|uniprotkb:Q8WYL9|uniprotkb:Q8WYM0|uniprotkb:Q8WYM1|uniprotkb:O43522|intact:EBI-1002160|ensembl:ENSP00000376943	psi-mi:f1_vaccp(display_long)|uniprotkb:F1L(orf name)	psi-mi:b2l11_human(display_long)|uniprotkb:BCL2L11(gene name)|psi-mi:BCL2L11(display_short)|uniprotkb:BIM(gene name synonym)|uniprotkb:Bcl2-interacting mediator of cell death(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kvansakul et al. (2008)	pubmed:18551131|mint:MINT-6629173|doi:10.1038/cdd.2008.83	taxid:31531(vaccp)|taxid:31531("Vaccinia virus (strain L-IVP) (VACV)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7973674|mint:MINT-6629196	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P68451|go:"GO:0019050"(suppression by virus of host apoptotic process)|interpro:IPR021119|interpro:IPR011207(Uncharacterized conserved protein UCP015971, VAC-F1L)|interpro:IPR036834|mint:MINT-6629197(identity)|uniprotkb:P68451(P68451)	refseq:NP_001191035.1|refseq:NP_001191036.1|refseq:NP_001191037.1|refseq:NP_001191038.1|refseq:NP_001191039.1|refseq:NP_001191040.1|refseq:NP_001191041.1|refseq:NP_001191042.1|refseq:NP_006529.1|refseq:NP_619527.1|refseq:NP_619528.1|refseq:NP_619529.1|refseq:NP_619530.1|refseq:NP_619531.1|refseq:NP_619532.1|refseq:NP_619533.1|refseq:NP_996885.1|refseq:NP_996886.1|ensembl:ENSG00000153094(gene)|ensembl:ENST00000393256(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001822"(kidney development)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007127"(meiosis I)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008584"(male gonad development)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0012505"(endomembrane system)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030879"(mammary gland development)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0034263"(positive regulation of autophagy in response to ER overload)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035148"(tube formation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043583"(ear development)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048070"(regulation of developmental pigmentation)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0060139"(positive regulation of apoptotic process by virus)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097140"(BIM-BCL-xl complex)|go:"GO:0097141"(BIM-BCL-2 complex)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:1902110"(positive regulation of mitochondrial membrane permeability involved in apoptotic process)|reactome:R-HSA-111453|reactome:R-HSA-193648|reactome:R-HSA-6802952|reactome:R-HSA-8862803|reactome:R-HSA-8952158|reactome:R-HSA-9607240|reactome:R-HSA-9614657|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902263"(apoptotic process involved in embryonic digit morphogenesis)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR014771(Apoptosis, Bim N-terminal)|interpro:IPR015040(Bcl-x interacting)|interpro:IPR017288(Apoptosis, Bcl-2-like protein 11)|mint:O43521|rcsb pdb:1F95|rcsb pdb:2K7W|rcsb pdb:2NL9|rcsb pdb:2V6Q|rcsb pdb:2VM6|rcsb pdb:2WH6|rcsb pdb:2YQ6|rcsb pdb:2YQ7|rcsb pdb:3D7V|rcsb pdb:3FDL|rcsb pdb:3IO8|rcsb pdb:3IO9|rcsb pdb:3KJ0|rcsb pdb:3KJ1|rcsb pdb:3KJ2|rcsb pdb:4A1U|rcsb pdb:4A1W|rcsb pdb:4B4S|rcsb pdb:4D2M|rcsb pdb:4QVF|rcsb pdb:4UF3|rcsb pdb:4YJ4|rcsb pdb:4ZIE|rcsb pdb:4ZIF|rcsb pdb:4ZIH|rcsb pdb:5AGW|rcsb pdb:5AGX|rcsb pdb:5C3G|rcsb pdb:5VWV|rcsb pdb:5VWW|rcsb pdb:5VWX|rcsb pdb:5VWY|rcsb pdb:5VWZ|rcsb pdb:5VX0|rcsb pdb:5VX2|rcsb pdb:5VX3|rcsb pdb:5WOS|rcsb pdb:6QFI|rcsb pdb:6RJP|rcsb pdb:6TQQ|rcsb pdb:6UA3|rcsb pdb:6UAB|rcsb pdb:6VBX|rcsb pdb:6X8O|reactome:R-HSA-111446|dip:DIP-29185N|mint:MINT-6629199(identity)|uniprotkb:O43521(O43521)	-	comment:"fragmentation type: fragment"|comment:mint	-	figure legend:F3 SF1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/26	2014/10/16	rogid:8/tlI/TrxzhDdoIWa9PQpYrcPMA31531	rogid:YvDxFP1kVEoSiz67PVpE4ZM5wWI9606	intact-crc:21232BFCED2B7480|rigid:qehZ61mP/t9hhDq1sS8BG6d/7IE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P68451	uniprotkb:Q91ZE9	intact:EBI-7066119|uniprotkb:P21091|intact:MINT-6629061	intact:EBI-708032|uniprotkb:Q8BUK0|ensembl:ENSMUSP00000159051	psi-mi:f1_vaccp(display_long)|uniprotkb:F1L(orf name)	psi-mi:bmf_mouse(display_long)|uniprotkb:Bmf(gene name)|psi-mi:Bmf(display_short)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kvansakul et al. (2008)	pubmed:18551131|mint:MINT-6629173|doi:10.1038/cdd.2008.83	taxid:31531(vaccp)|taxid:31531("Vaccinia virus (strain L-IVP) (VACV)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7973687|mint:MINT-6629201	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P68451|go:"GO:0019050"(suppression by virus of host apoptotic process)|interpro:IPR021119|interpro:IPR011207(Uncharacterized conserved protein UCP015971, VAC-F1L)|interpro:IPR036834|mint:MINT-6629202(identity)|uniprotkb:P68451(P68451)	refseq:NP_612186.2|refseq:XP_006498918.1|refseq:NP_001318150.1|dip:DIP-29806N|ensembl:ENSMUSG00000040093(gene)|ensembl:ENSMUST00000125860(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005737"(cytoplasm)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043276"(anoikis)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:1904093"(negative regulation of autophagic cell death)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR028192|mint:Q91ZE9|rcsb pdb:2VOG|reactome:R-MMU-111453|reactome:R-MMU-139910|mint:MINT-6629204(identity)|uniprotkb:Q91ZE9(Q91ZE9)	-	comment:"fragmentation type: fragment"|comment:mint	-	figure legend:F3 SF1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/26	2014/10/16	rogid:8/tlI/TrxzhDdoIWa9PQpYrcPMA31531	rogid:TuX2CXkbIbnDcK+gYw7T0AyD5zo10090	intact-crc:0B43330A0A1DEABA|rigid:2lWCPvai0oqI4o2hM2QJdxa/QIE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P68451	uniprotkb:P55957	intact:EBI-7066119|uniprotkb:P21091|intact:MINT-6629061	intact:EBI-519672|uniprotkb:Q549M7|uniprotkb:Q71T04|uniprotkb:Q7Z4M9|ensembl:ENSP00000449236|ensembl:ENSP00000480414|uniprotkb:Q8IY86	psi-mi:f1_vaccp(display_long)|uniprotkb:F1L(orf name)	psi-mi:bid_human(display_long)|uniprotkb:p22 BID(gene name synonym)|uniprotkb:BID(gene name)|psi-mi:BID(display_short)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kvansakul et al. (2008)	pubmed:18551131|mint:MINT-6629173|doi:10.1038/cdd.2008.83	taxid:31531(vaccp)|taxid:31531("Vaccinia virus (strain L-IVP) (VACV)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7973661|mint:MINT-6629191	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P68451|go:"GO:0019050"(suppression by virus of host apoptotic process)|interpro:IPR021119|interpro:IPR011207(Uncharacterized conserved protein UCP015971, VAC-F1L)|interpro:IPR036834|mint:MINT-6629192(identity)|uniprotkb:P68451(P68451)	ensembl:ENSG00000015475(gene)|ensembl:ENST00000551952(transcript)|ensembl:ENST00000622694(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002931"(response to ischemia)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0034263"(positive regulation of autophagy in response to ER overload)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR010479(BH3 interacting)|interpro:IPR020728|interpro:IPR036834|mint:P55957|rcsb pdb:1ZY3|rcsb pdb:2BID|rcsb pdb:2KBW|rcsb pdb:2M5B|rcsb pdb:2M5I|rcsb pdb:4BD2|rcsb pdb:4QVE|rcsb pdb:4ZEQ|rcsb pdb:4ZIG|rcsb pdb:4ZII|rcsb pdb:5AJJ|rcsb pdb:5C3F|reactome:R-HSA-111447|reactome:R-HSA-111452|reactome:R-HSA-111453|reactome:R-HSA-114294|reactome:R-HSA-6803204|reactome:R-HSA-75108|go:"GO:0005123"(death receptor binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007420"(brain development)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|refseq:NP_001187.1|refseq:NP_932070.1|refseq:NP_001231498.1|refseq:NP_001231499.1|refseq:NP_001231501.1|refseq:NP_932071.1|refseq:NP_001231496.1|dip:DIP-34937N|mint:MINT-6629194(identity)|uniprotkb:P55957(P55957)	-	comment:"fragmentation type: fragment"|comment:mint	-	figure legend:F3 SF1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/26	2014/10/16	rogid:8/tlI/TrxzhDdoIWa9PQpYrcPMA31531	rogid:K7148hFL21ctiVuJRKEsddUE3tc9606	intact-crc:974123692EC686D7|rigid:vwZJGGUeR1ZwUG4MyS4+dQh2Lxk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P68451	uniprotkb:Q13794	intact:EBI-7066119|uniprotkb:P21091|intact:MINT-6629061	intact:EBI-707392|uniprotkb:B2R4T7|uniprotkb:Q8N589|ensembl:ENSP00000326119	psi-mi:f1_vaccp(display_long)|uniprotkb:F1L(orf name)	psi-mi:apr_human(display_long)|uniprotkb:NOXA(gene name synonym)|uniprotkb:Immediate-early-response protein APR(gene name synonym)|uniprotkb:PMAIP1(gene name)|psi-mi:PMAIP1(display_short)|uniprotkb:Protein Noxa(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kvansakul et al. (2008)	pubmed:18551131|mint:MINT-6629173|doi:10.1038/cdd.2008.83	taxid:31531(vaccp)|taxid:31531("Vaccinia virus (strain L-IVP) (VACV)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7973737|mint:MINT-6629211	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P68451|go:"GO:0019050"(suppression by virus of host apoptotic process)|interpro:IPR021119|interpro:IPR011207(Uncharacterized conserved protein UCP015971, VAC-F1L)|interpro:IPR036834|mint:MINT-6629212(identity)|uniprotkb:P68451(P68451)	refseq:NP_066950.1|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051607"(defense response to virus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR024140|mint:Q13794|rcsb pdb:3MQP|reactome:R-HSA-111448|reactome:R-HSA-111453|reactome:R-HSA-6803204|ensembl:ENSG00000141682(gene)|ensembl:ENST00000316660(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043331"(response to dsRNA)|mint:MINT-6629214(identity)|uniprotkb:Q13794(Q13794)	-	comment:"fragmentation type: fragment"|comment:mint	-	figure legend:F3 SF1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/26	2014/10/16	rogid:8/tlI/TrxzhDdoIWa9PQpYrcPMA31531	rogid:IDaNRhZNKHvwyF0oqi9mPw+mBnc9606	intact-crc:F3A9FDBE33D7C34E|rigid:DXyw/IKjhq+cJoutedUgZK473Q4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P68451	uniprotkb:P62816	intact:EBI-7066119|uniprotkb:P21091|intact:MINT-6629061	intact:EBI-7973700|uniprotkb:P70678|intact:UNK-5382108|ensembl:ENSMUSP00000057532	psi-mi:f1_vaccp(display_long)|uniprotkb:F1L(orf name)	psi-mi:hrk_mouse(display_long)|uniprotkb:BH3-interacting domain-containing protein 3(gene name synonym)|uniprotkb:Hrk(gene name)|psi-mi:Hrk(display_short)|uniprotkb:Bid3(gene name synonym)|uniprotkb:Dp5(gene name synonym)|uniprotkb:Neuronal death protein DP5(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kvansakul et al. (2008)	pubmed:18551131|mint:MINT-6629173|doi:10.1038/cdd.2008.83	taxid:31531(vaccp)|taxid:31531("Vaccinia virus (strain L-IVP) (VACV)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7973724|mint:MINT-6629206	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P68451|go:"GO:0019050"(suppression by virus of host apoptotic process)|interpro:IPR021119|interpro:IPR011207(Uncharacterized conserved protein UCP015971, VAC-F1L)|interpro:IPR036834|mint:MINT-6629207(identity)|uniprotkb:P68451(P68451)	refseq:NP_031571.1|ensembl:ENSMUSG00000046607(gene)|ensembl:ENSMUST00000054836(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0051365"(cellular response to potassium ion starvation)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|interpro:IPR017249(Apoptosis, activator harakiri)|interpro:IPR020728|mint:P62816|mint:MINT-6629209(identity)|uniprotkb:P62816(P62816)	-	comment:"fragmentation type: fragment"|comment:mint	comment:mint|function:"Activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L)"	figure legend:F3 SF1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/26	2014/10/16	rogid:8/tlI/TrxzhDdoIWa9PQpYrcPMA31531	rogid:7A70T1XMLb1vN0nN+KdWj3Wv2x010090	intact-crc:F7A5360EBEB46C6E|rigid:PyUcHr0S4qoN1biU0Wa50ivq6R8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P68451	uniprotkb:Q4JG03	intact:EBI-7066119|uniprotkb:P21091|intact:MINT-6629061	intact:EBI-7973769|intact:UNK-5424865	psi-mi:f1_vaccp(display_long)|uniprotkb:F1L(orf name)	psi-mi:q4jg03_mouse(display_long)|uniprotkb:Huwe1(gene name)|psi-mi:Huwe1(display_short)|uniprotkb:Mule(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kvansakul et al. (2008)	pubmed:18551131|mint:MINT-6629173|doi:10.1038/cdd.2008.83	taxid:31531(vaccp)|taxid:31531("Vaccinia virus (strain L-IVP) (VACV)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7973763|mint:MINT-6629221	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P68451|go:"GO:0019050"(suppression by virus of host apoptotic process)|interpro:IPR021119|interpro:IPR011207(Uncharacterized conserved protein UCP015971, VAC-F1L)|interpro:IPR036834|mint:MINT-6629222(identity)|uniprotkb:P68451(P68451)	interpro:IPR025527|interpro:IPR000569(HECT)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR004170(WWE)|interpro:IPR010314(E3 ubiquitin ligase, region of unknown function DUF913)|refseq:NP_067498.4|interpro:IPR016024(Armadillo-type fold)|interpro:IPR010309(E3 ubiquitin ligase, region of unknown function DUF908)|mint:Q4JG03|interpro:IPR035983|interpro:IPR037197|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0016874"(ligase activity)|interpro:IPR041918|mint:MINT-6629224(identity)|uniprotkb:Q4JG03(Q4JG03)	-	comment:"fragmentation type: fragment"|comment:mint	comment:mint	figure legend:F3 SF1|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/26	2014/10/16	rogid:8/tlI/TrxzhDdoIWa9PQpYrcPMA31531	rogid:hhRZzelxNfky7S1j+lwdF4sHTGM10090	intact-crc:B8C3600961695A31|rigid:+Vvfs/2GwQcZv0jNOCaxaBABs80	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P68451	uniprotkb:O88597	intact:EBI-7066119|uniprotkb:P21091|intact:MINT-6629061	intact:EBI-643716|uniprotkb:Q99J03|ensembl:ENSMUSP00000119369	psi-mi:f1_vaccp(display_long)|uniprotkb:F1L(orf name)	psi-mi:becn1_mouse(display_long)|uniprotkb:Coiled-coil myosin-like BCL2-interacting protein(gene name synonym)|uniprotkb:Becn1(gene name)|psi-mi:Becn1(display_short)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kvansakul et al. (2008)	pubmed:18551131|mint:MINT-6629173|doi:10.1038/cdd.2008.83	taxid:31531(vaccp)|taxid:31531("Vaccinia virus (strain L-IVP) (VACV)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7973802|mint:MINT-6629226	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P68451|go:"GO:0019050"(suppression by virus of host apoptotic process)|interpro:IPR021119|interpro:IPR011207(Uncharacterized conserved protein UCP015971, VAC-F1L)|interpro:IPR036834|mint:MINT-6629227(identity)|uniprotkb:P68451(P68451)	refseq:NP_062530.2|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033197"(response to vitamin E)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048666"(neuron development)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0051607"(defense response to virus)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071275"(cellular response to aluminum ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1905672"(negative regulation of lysosome organization)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000786"(positive regulation of autophagosome assembly)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR029318|interpro:IPR032913|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|mint:O88597|rcsb pdb:3BL2|rcsb pdb:5YR0|reactome:R-MMU-1632852|reactome:R-MMU-5689880|go:"GO:0010288"(response to lead ion)|ensembl:ENSMUSG00000035086(gene)|ensembl:ENSMUST00000130916(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007040"(lysosome organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007568"(aging)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010040"("response to iron(II) ion")|dip:DIP-41636N|mint:MINT-6629229(identity)|uniprotkb:O88597(O88597)	-	comment:"fragmentation type: fragment"|comment:mint	-	figure legend:F3 SF1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/26	2014/10/16	rogid:8/tlI/TrxzhDdoIWa9PQpYrcPMA31531	rogid:uQ3D8xs/5TTtmm08qbcSmU7CmiE10090	intact-crc:A43D6D153FCF8B63|rigid:sppx5TntAdk+dnyIfjMoDZv1Xls	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P68451	uniprotkb:Q9BXH1	intact:EBI-7066119|uniprotkb:P21091|intact:MINT-6629061	intact:EBI-519884|uniprotkb:O00171|uniprotkb:Q96PG9|ensembl:ENSP00000395862|uniprotkb:B9EGI3	psi-mi:f1_vaccp(display_long)|uniprotkb:F1L(orf name)	psi-mi:bbc3_human(display_long)|uniprotkb:p53 up-regulated modulator of apoptosis(gene name synonym)|uniprotkb:JFY-1(gene name synonym)|uniprotkb:BBC3(gene name)|psi-mi:BBC3(display_short)|uniprotkb:PUMA(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kvansakul et al. (2008)	pubmed:18551131|mint:MINT-6629173|doi:10.1038/cdd.2008.83	taxid:31531(vaccp)|taxid:31531("Vaccinia virus (strain L-IVP) (VACV)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7973750|mint:MINT-6629216	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P68451|go:"GO:0019050"(suppression by virus of host apoptotic process)|interpro:IPR021119|interpro:IPR011207(Uncharacterized conserved protein UCP015971, VAC-F1L)|interpro:IPR036834|mint:MINT-6629217(identity)|uniprotkb:P68451(P68451)	refseq:NP_001120713.1|refseq:NP_055232.1|refseq:XP_006723204.1|ensembl:ENSG00000105327(gene)|ensembl:ENST00000439096(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032464"(positive regulation of protein homooligomerization)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:1900740"(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway)|go:"GO:1901998"(toxin transport)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR031661|mint:Q9BXH1|rcsb pdb:2M04|rcsb pdb:4BPI|rcsb pdb:4BPJ|rcsb pdb:4BPK|rcsb pdb:4HNJ|rcsb pdb:5UUL|rcsb pdb:6QFM|rcsb pdb:6QG8|rcsb pdb:6TQP|reactome:R-HSA-111453|reactome:R-HSA-139915|reactome:R-HSA-6803204|reactome:R-HSA-9614657|refseq:NP_001120712.1|refseq:NP_001120714.1|dip:DIP-29215N|mint:MINT-6629219(identity)|uniprotkb:Q9BXH1(Q9BXH1)	-	comment:"fragmentation type: fragment"|comment:mint	-	figure legend:F3 SF1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/26	2014/10/16	rogid:8/tlI/TrxzhDdoIWa9PQpYrcPMA31531	rogid:rWcs573MgFjZoNgLuPltNrK/8pU9606	intact-crc:D09C030A0383D045|rigid:odQv1uwsfp1WuoHxioDCQHOohSg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)