#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P10242 uniprotkb:P21333 intact:EBI-298355|uniprotkb:P78391|uniprotkb:P78392|uniprotkb:P78525|uniprotkb:P78526|uniprotkb:Q14023|uniprotkb:Q14024|uniprotkb:Q9UE83|uniprotkb:Q708E4|uniprotkb:Q708E7|ensembl:ENSP00000356788|uniprotkb:E9PNL6|uniprotkb:E9PI07|uniprotkb:E9PLZ5|uniprotkb:E9PNA4|uniprotkb:E9PRS2 intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|ensembl:ENSP00000358866|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45 psi-mi:myb_human(display_long)|uniprotkb:MYB(gene name)|psi-mi:MYB(display_short)|uniprotkb:Proto-oncogene c-Myb(gene name synonym) psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yamauchi et al. (2008) pubmed:18548008|imex:IM-9553|mint:MINT-6802025|doi:10.1038/emboj.2008.118 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7971045|mint:MINT-6802049|imex:IM-9553-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001155129.1|refseq:NP_001155130.1|refseq:NP_001155131.1|refseq:NP_001155132.1|refseq:NP_001123644.1|refseq:NP_001123645.1|refseq:NP_005366.2|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1904899"(positive regulation of hepatic stellate cell proliferation)|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|go:"GO:2000845"(positive regulation of testosterone secretion)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR012642(Mitotic Wos2)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|mint:P10242|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000118513(gene)|ensembl:ENST00000367814(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045624"(positive regulation of T-helper cell differentiation)|refseq:NP_001155128.1|dip:DIP-1057N|mint:MINT-6802051(identity) go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:1902396"(protein localization to bicellular tight junction)|refseq:NP_001104026.1|refseq:NP_001447.2|ensembl:ENSG00000196924(gene)|ensembl:ENST00000369850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097368"(establishment of Sertoli cell barrier)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:0046332"(SMAD binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|rcsb pdb:6EW1|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|dip:DIP-1136N|mint:MINT-6802052(identity) - - - figure legend:F1A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/11/28 2014/10/16 rogid:do/bvngcNTqnh1KZE4vDAtPP0749606 rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606 intact-crc:CDD005A8FCD73370|rigid:1MEMSJDTJw8KRGN9H8/vSfNCU3k false tandem tag:?-?(MINT-6802062) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P10242 uniprotkb:Q13813 intact:EBI-298355|uniprotkb:P78391|uniprotkb:P78392|uniprotkb:P78525|uniprotkb:P78526|uniprotkb:Q14023|uniprotkb:Q14024|uniprotkb:Q9UE83|uniprotkb:Q708E4|uniprotkb:Q708E7|ensembl:ENSP00000356788|uniprotkb:E9PNL6|uniprotkb:E9PI07|uniprotkb:E9PLZ5|uniprotkb:E9PNA4|uniprotkb:E9PRS2 intact:EBI-351450|uniprotkb:Q13186|uniprotkb:Q15324|uniprotkb:Q16606|uniprotkb:Q59EF1|uniprotkb:Q5VXV5|uniprotkb:Q5VXV6|uniprotkb:Q7Z6M5|uniprotkb:Q9P0V0|intact:EBI-4404719|intact:EBI-28985930|ensembl:ENSP00000361816 psi-mi:myb_human(display_long)|uniprotkb:MYB(gene name)|psi-mi:MYB(display_short)|uniprotkb:Proto-oncogene c-Myb(gene name synonym) psi-mi:sptn1_human(display_long)|uniprotkb:SPTAN1(gene name)|psi-mi:SPTAN1(display_short)|uniprotkb:SPTA2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:NEAS(gene name synonym)|uniprotkb:Spectrin, non-erythroid alpha subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yamauchi et al. (2008) pubmed:18548008|imex:IM-9553|mint:MINT-6802025|doi:10.1038/emboj.2008.118 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7971045|mint:MINT-6802049|imex:IM-9553-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001155129.1|refseq:NP_001155130.1|refseq:NP_001155131.1|refseq:NP_001155132.1|refseq:NP_001123644.1|refseq:NP_001123645.1|refseq:NP_005366.2|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1904899"(positive regulation of hepatic stellate cell proliferation)|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|go:"GO:2000845"(positive regulation of testosterone secretion)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR012642(Mitotic Wos2)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|mint:P10242|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000118513(gene)|ensembl:ENST00000367814(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045624"(positive regulation of T-helper cell differentiation)|refseq:NP_001155128.1|dip:DIP-1057N|mint:MINT-6802051(identity) refseq:NP_001123910.1|refseq:NP_001182461.1|refseq:NP_003118.2|ensembl:ENSG00000197694(gene)|ensembl:ENST00000372731(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:Q13813|rcsb pdb:2FOT|rcsb pdb:3F31|rcsb pdb:3FB2|rcsb pdb:5FW9|rcsb pdb:5FWB|rcsb pdb:5FWC|rcsb pdb:6ZEH|reactome:R-HSA-264870|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|ensembl:ENST00000358161|ensembl:ENSP00000350882|ensembl:ENSP00000361816|ensembl:ENST00000372739|ensembl:ENSP00000361824|dip:DIP-33141N|mint:MINT-6802053(identity) - - - figure legend:F1A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/11/28 2014/10/16 rogid:do/bvngcNTqnh1KZE4vDAtPP0749606 rogid:3d5XlsH+PSg32qNR/ZiooAJ/wH89606 intact-crc:CDD005A8FCD73370|rigid:1MEMSJDTJw8KRGN9H8/vSfNCU3k false tandem tag:?-?(MINT-6802062) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P10242 uniprotkb:Q00610 intact:EBI-298355|uniprotkb:P78391|uniprotkb:P78392|uniprotkb:P78525|uniprotkb:P78526|uniprotkb:Q14023|uniprotkb:Q14024|uniprotkb:Q9UE83|uniprotkb:Q708E4|uniprotkb:Q708E7|ensembl:ENSP00000356788|uniprotkb:E9PNL6|uniprotkb:E9PI07|uniprotkb:E9PLZ5|uniprotkb:E9PNA4|uniprotkb:E9PRS2 intact:EBI-354967|intact:EBI-28974011|ensembl:ENSP00000269122|uniprotkb:Q6N0A0|uniprotkb:Q86TF2|uniprotkb:D3DU00 psi-mi:myb_human(display_long)|uniprotkb:MYB(gene name)|psi-mi:MYB(display_short)|uniprotkb:Proto-oncogene c-Myb(gene name synonym) psi-mi:clh1_human(display_long)|uniprotkb:Clathrin heavy chain on chromosome 17(gene name synonym)|uniprotkb:CLTC(gene name)|psi-mi:CLTC(display_short)|uniprotkb:CLH17(gene name synonym)|uniprotkb:KIAA0034(gene name synonym)|uniprotkb:CLTCL2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yamauchi et al. (2008) pubmed:18548008|imex:IM-9553|mint:MINT-6802025|doi:10.1038/emboj.2008.118 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7971045|mint:MINT-6802049|imex:IM-9553-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001155129.1|refseq:NP_001155130.1|refseq:NP_001155131.1|refseq:NP_001155132.1|refseq:NP_001123644.1|refseq:NP_001123645.1|refseq:NP_005366.2|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1904899"(positive regulation of hepatic stellate cell proliferation)|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|go:"GO:2000845"(positive regulation of testosterone secretion)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR012642(Mitotic Wos2)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|mint:P10242|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000118513(gene)|ensembl:ENST00000367814(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045624"(positive regulation of T-helper cell differentiation)|refseq:NP_001155128.1|dip:DIP-1057N|mint:MINT-6802051(identity) ensembl:ENSG00000141367(gene)|ensembl:ENST00000269122(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_004850.1|ensembl:ENSP00000269122|ensembl:ENST00000393043|ensembl:ENSP00000376763|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q00610|rcsb pdb:2XZG|rcsb pdb:4G55|rcsb pdb:6E4L|rcsb pdb:6QNN|rcsb pdb:6QNP|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9013420|reactome:R-HSA-9013424|mint:MINT-6802054(identity) - - - figure legend:F1A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/11/28 2014/10/16 rogid:do/bvngcNTqnh1KZE4vDAtPP0749606 rogid:oGsLXL5J5MHO+ronpDIG9hJ11sU9606 intact-crc:CDD005A8FCD73370|rigid:1MEMSJDTJw8KRGN9H8/vSfNCU3k false tandem tag:?-?(MINT-6802062) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P10242 uniprotkb:P09496 intact:EBI-298355|uniprotkb:P78391|uniprotkb:P78392|uniprotkb:P78525|uniprotkb:P78526|uniprotkb:Q14023|uniprotkb:Q14024|uniprotkb:Q9UE83|uniprotkb:Q708E4|uniprotkb:Q708E7|ensembl:ENSP00000356788|uniprotkb:E9PNL6|uniprotkb:E9PI07|uniprotkb:E9PLZ5|uniprotkb:E9PNA4|uniprotkb:E9PRS2 intact:EBI-1171169|uniprotkb:Q2XPN5|uniprotkb:Q53XZ1|uniprotkb:A8K4W3|uniprotkb:B4DIN1|uniprotkb:F5H6N3|ensembl:ENSP00000242285|ensembl:ENSP00000401019 psi-mi:myb_human(display_long)|uniprotkb:MYB(gene name)|psi-mi:MYB(display_short)|uniprotkb:Proto-oncogene c-Myb(gene name synonym) psi-mi:clca_human(display_long)|uniprotkb:CLTA(gene name)|psi-mi:CLTA(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yamauchi et al. (2008) pubmed:18548008|imex:IM-9553|mint:MINT-6802025|doi:10.1038/emboj.2008.118 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7971080|mint:MINT-6802072|imex:IM-9553-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001155129.1|refseq:NP_001155130.1|refseq:NP_001155131.1|refseq:NP_001155132.1|refseq:NP_001123644.1|refseq:NP_001123645.1|refseq:NP_005366.2|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1904899"(positive regulation of hepatic stellate cell proliferation)|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|go:"GO:2000845"(positive regulation of testosterone secretion)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR012642(Mitotic Wos2)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|mint:P10242|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000118513(gene)|ensembl:ENST00000367814(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045624"(positive regulation of T-helper cell differentiation)|refseq:NP_001155128.1|dip:DIP-1057N|mint:MINT-6802080(identity) refseq:NP_001070145.1|refseq:NP_001824.1|refseq:NP_009027.1|refseq:NP_001171689.1|refseq:NP_001171691.1|ensembl:ENSG00000122705(gene)|ensembl:ENST00000242285(transcript)|ensembl:ENST00000433436(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0030118"(clathrin coat)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042277"(peptide binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0099631"(postsynaptic endocytic zone cytoplasmic component)|interpro:IPR000996(Clathrin light chain)|mint:P09496|rcsb pdb:6E5N|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-3928665|mint:MINT-6802116(identity) - - - figure legend:F1B F2B F2C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/11/28 2014/10/16 rogid:do/bvngcNTqnh1KZE4vDAtPP0749606 rogid:RCF3QpQKI1yZFOTAyzhvRkR9ek49606 intact-crc:82B992A4F7B1B92D|rigid:vDp9HKg94lIAfr/NUa9MoA8w8oQ false tandem tag:?-?(MINT-6802081) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P10242 uniprotkb:Q13813 intact:EBI-298355|uniprotkb:P78391|uniprotkb:P78392|uniprotkb:P78525|uniprotkb:P78526|uniprotkb:Q14023|uniprotkb:Q14024|uniprotkb:Q9UE83|uniprotkb:Q708E4|uniprotkb:Q708E7|ensembl:ENSP00000356788|uniprotkb:E9PNL6|uniprotkb:E9PI07|uniprotkb:E9PLZ5|uniprotkb:E9PNA4|uniprotkb:E9PRS2 intact:EBI-351450|uniprotkb:Q13186|uniprotkb:Q15324|uniprotkb:Q16606|uniprotkb:Q59EF1|uniprotkb:Q5VXV5|uniprotkb:Q5VXV6|uniprotkb:Q7Z6M5|uniprotkb:Q9P0V0|intact:EBI-4404719|intact:EBI-28985930|ensembl:ENSP00000361816 psi-mi:myb_human(display_long)|uniprotkb:MYB(gene name)|psi-mi:MYB(display_short)|uniprotkb:Proto-oncogene c-Myb(gene name synonym) psi-mi:sptn1_human(display_long)|uniprotkb:SPTAN1(gene name)|psi-mi:SPTAN1(display_short)|uniprotkb:SPTA2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:NEAS(gene name synonym)|uniprotkb:Spectrin, non-erythroid alpha subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yamauchi et al. (2008) pubmed:18548008|imex:IM-9553|mint:MINT-6802025|doi:10.1038/emboj.2008.118 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7971080|mint:MINT-6802072|imex:IM-9553-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001155129.1|refseq:NP_001155130.1|refseq:NP_001155131.1|refseq:NP_001155132.1|refseq:NP_001123644.1|refseq:NP_001123645.1|refseq:NP_005366.2|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1904899"(positive regulation of hepatic stellate cell proliferation)|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|go:"GO:2000845"(positive regulation of testosterone secretion)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR012642(Mitotic Wos2)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|mint:P10242|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000118513(gene)|ensembl:ENST00000367814(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045624"(positive regulation of T-helper cell differentiation)|refseq:NP_001155128.1|dip:DIP-1057N|mint:MINT-6802080(identity) refseq:NP_001123910.1|refseq:NP_001182461.1|refseq:NP_003118.2|ensembl:ENSG00000197694(gene)|ensembl:ENST00000372731(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:Q13813|rcsb pdb:2FOT|rcsb pdb:3F31|rcsb pdb:3FB2|rcsb pdb:5FW9|rcsb pdb:5FWB|rcsb pdb:5FWC|rcsb pdb:6ZEH|reactome:R-HSA-264870|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|ensembl:ENST00000358161|ensembl:ENSP00000350882|ensembl:ENSP00000361816|ensembl:ENST00000372739|ensembl:ENSP00000361824|dip:DIP-33141N|mint:MINT-6802076(identity) - - - figure legend:F1B F2B F2C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/11/28 2014/10/16 rogid:do/bvngcNTqnh1KZE4vDAtPP0749606 rogid:3d5XlsH+PSg32qNR/ZiooAJ/wH89606 intact-crc:82B992A4F7B1B92D|rigid:vDp9HKg94lIAfr/NUa9MoA8w8oQ false tandem tag:?-?(MINT-6802081) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P10242 uniprotkb:Q00610 intact:EBI-298355|uniprotkb:P78391|uniprotkb:P78392|uniprotkb:P78525|uniprotkb:P78526|uniprotkb:Q14023|uniprotkb:Q14024|uniprotkb:Q9UE83|uniprotkb:Q708E4|uniprotkb:Q708E7|ensembl:ENSP00000356788|uniprotkb:E9PNL6|uniprotkb:E9PI07|uniprotkb:E9PLZ5|uniprotkb:E9PNA4|uniprotkb:E9PRS2 intact:EBI-354967|intact:EBI-28974011|ensembl:ENSP00000269122|uniprotkb:Q6N0A0|uniprotkb:Q86TF2|uniprotkb:D3DU00 psi-mi:myb_human(display_long)|uniprotkb:MYB(gene name)|psi-mi:MYB(display_short)|uniprotkb:Proto-oncogene c-Myb(gene name synonym) psi-mi:clh1_human(display_long)|uniprotkb:Clathrin heavy chain on chromosome 17(gene name synonym)|uniprotkb:CLTC(gene name)|psi-mi:CLTC(display_short)|uniprotkb:CLH17(gene name synonym)|uniprotkb:KIAA0034(gene name synonym)|uniprotkb:CLTCL2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yamauchi et al. (2008) pubmed:18548008|imex:IM-9553|mint:MINT-6802025|doi:10.1038/emboj.2008.118 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7971080|mint:MINT-6802072|imex:IM-9553-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001155129.1|refseq:NP_001155130.1|refseq:NP_001155131.1|refseq:NP_001155132.1|refseq:NP_001123644.1|refseq:NP_001123645.1|refseq:NP_005366.2|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1904899"(positive regulation of hepatic stellate cell proliferation)|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|go:"GO:2000845"(positive regulation of testosterone secretion)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR012642(Mitotic Wos2)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|mint:P10242|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000118513(gene)|ensembl:ENST00000367814(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045624"(positive regulation of T-helper cell differentiation)|refseq:NP_001155128.1|dip:DIP-1057N|mint:MINT-6802080(identity) ensembl:ENSG00000141367(gene)|ensembl:ENST00000269122(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_004850.1|ensembl:ENSP00000269122|ensembl:ENST00000393043|ensembl:ENSP00000376763|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q00610|rcsb pdb:2XZG|rcsb pdb:4G55|rcsb pdb:6E4L|rcsb pdb:6QNN|rcsb pdb:6QNP|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9013420|reactome:R-HSA-9013424|mint:MINT-6802074(identity) - - - figure legend:F1B F2B F2C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/11/28 2014/10/16 rogid:do/bvngcNTqnh1KZE4vDAtPP0749606 rogid:oGsLXL5J5MHO+ronpDIG9hJ11sU9606 intact-crc:82B992A4F7B1B92D|rigid:vDp9HKg94lIAfr/NUa9MoA8w8oQ false tandem tag:?-?(MINT-6802081) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P10242 uniprotkb:P21333 intact:EBI-298355|uniprotkb:P78391|uniprotkb:P78392|uniprotkb:P78525|uniprotkb:P78526|uniprotkb:Q14023|uniprotkb:Q14024|uniprotkb:Q9UE83|uniprotkb:Q708E4|uniprotkb:Q708E7|ensembl:ENSP00000356788|uniprotkb:E9PNL6|uniprotkb:E9PI07|uniprotkb:E9PLZ5|uniprotkb:E9PNA4|uniprotkb:E9PRS2 intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|ensembl:ENSP00000358866|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45 psi-mi:myb_human(display_long)|uniprotkb:MYB(gene name)|psi-mi:MYB(display_short)|uniprotkb:Proto-oncogene c-Myb(gene name synonym) psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yamauchi et al. (2008) pubmed:18548008|imex:IM-9553|mint:MINT-6802025|doi:10.1038/emboj.2008.118 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7971080|mint:MINT-6802072|imex:IM-9553-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001155129.1|refseq:NP_001155130.1|refseq:NP_001155131.1|refseq:NP_001155132.1|refseq:NP_001123644.1|refseq:NP_001123645.1|refseq:NP_005366.2|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1904899"(positive regulation of hepatic stellate cell proliferation)|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|go:"GO:2000845"(positive regulation of testosterone secretion)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR012642(Mitotic Wos2)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|mint:P10242|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000118513(gene)|ensembl:ENST00000367814(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045624"(positive regulation of T-helper cell differentiation)|refseq:NP_001155128.1|dip:DIP-1057N|mint:MINT-6802080(identity) go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:1902396"(protein localization to bicellular tight junction)|refseq:NP_001104026.1|refseq:NP_001447.2|ensembl:ENSG00000196924(gene)|ensembl:ENST00000369850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097368"(establishment of Sertoli cell barrier)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:0046332"(SMAD binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|rcsb pdb:6EW1|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|dip:DIP-1136N|mint:MINT-6802078(identity) - - - figure legend:F1B F2B F2C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/11/28 2014/10/16 rogid:do/bvngcNTqnh1KZE4vDAtPP0749606 rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606 intact-crc:82B992A4F7B1B92D|rigid:vDp9HKg94lIAfr/NUa9MoA8w8oQ false tandem tag:?-?(MINT-6802081) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5TKA1 uniprotkb:P10242 intact:EBI-1389424|uniprotkb:Q5U5L8|uniprotkb:Q5U7E1|uniprotkb:Q6PI55|uniprotkb:Q6ZTV4|uniprotkb:Q7Z3J1|ensembl:ENSP00000505590 intact:EBI-298355|uniprotkb:P78391|uniprotkb:P78392|uniprotkb:P78525|uniprotkb:P78526|uniprotkb:Q14023|uniprotkb:Q14024|uniprotkb:Q9UE83|uniprotkb:Q708E4|uniprotkb:Q708E7|ensembl:ENSP00000356788|uniprotkb:E9PNL6|uniprotkb:E9PI07|uniprotkb:E9PLZ5|uniprotkb:E9PNA4|uniprotkb:E9PRS2 psi-mi:lin9_human(display_long)|uniprotkb:Beta subunit-associated regulator of apoptosis(gene name synonym)|uniprotkb:Type I interferon receptor beta chain-associated protein(gene name synonym)|uniprotkb:TUDOR gene similar protein(gene name synonym)|uniprotkb:pRB-associated protein(gene name synonym)|uniprotkb:LIN9(gene name)|psi-mi:LIN9(display_short)|uniprotkb:BARA(gene name synonym)|uniprotkb:TGS(gene name synonym) psi-mi:myb_human(display_long)|uniprotkb:MYB(gene name)|psi-mi:MYB(display_short)|uniprotkb:Proto-oncogene c-Myb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yamauchi et al. (2008) pubmed:18548008|imex:IM-9553|mint:MINT-6802025|doi:10.1038/emboj.2008.118 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7971155|mint:MINT-6802201|imex:IM-9553-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775106.2|refseq:NP_001257338.1|refseq:NP_001257339.1|ensembl:ENSG00000183814(gene)|ensembl:ENST00000681046(transcript)|go:"GO:0000003"(reproduction)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR010561(DIRP)|interpro:IPR033471|mint:Q5TKA1|rcsb pdb:6C48|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|go:"GO:0017053"(transcription repressor complex)|mint:MINT-6802205(identity) refseq:NP_001155129.1|refseq:NP_001155130.1|refseq:NP_001155131.1|refseq:NP_001155132.1|refseq:NP_001123644.1|refseq:NP_001123645.1|refseq:NP_005366.2|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1904899"(positive regulation of hepatic stellate cell proliferation)|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|go:"GO:2000845"(positive regulation of testosterone secretion)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR012642(Mitotic Wos2)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|mint:P10242|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000118513(gene)|ensembl:ENST00000367814(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045624"(positive regulation of T-helper cell differentiation)|refseq:NP_001155128.1|dip:DIP-1057N|mint:MINT-6802207(identity) - - - figure legend:F4C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/11/28 2014/10/16 rogid:ATFX38+7N6NzEysrzMmHvn22jaA9606 rogid:do/bvngcNTqnh1KZE4vDAtPP0749606 intact-crc:26B53FC5EC7B49AA|rigid:tfrqKNVuGeG/YFUZLb6C91A0ogk false ha tag:?-?(MINT-6802215) flag tag:?-?(MINT-6802210) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P10242 uniprotkb:P21333 intact:EBI-298355|uniprotkb:P78391|uniprotkb:P78392|uniprotkb:P78525|uniprotkb:P78526|uniprotkb:Q14023|uniprotkb:Q14024|uniprotkb:Q9UE83|uniprotkb:Q708E4|uniprotkb:Q708E7|ensembl:ENSP00000356788|uniprotkb:E9PNL6|uniprotkb:E9PI07|uniprotkb:E9PLZ5|uniprotkb:E9PNA4|uniprotkb:E9PRS2 intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|ensembl:ENSP00000358866|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45 psi-mi:myb_human(display_long)|uniprotkb:MYB(gene name)|psi-mi:MYB(display_short)|uniprotkb:Proto-oncogene c-Myb(gene name synonym) psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yamauchi et al. (2008) pubmed:18548008|imex:IM-9553|mint:MINT-6802025|doi:10.1038/emboj.2008.118 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7971131|mint:MINT-6802167|imex:IM-9553-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001155129.1|refseq:NP_001155130.1|refseq:NP_001155131.1|refseq:NP_001155132.1|refseq:NP_001123644.1|refseq:NP_001123645.1|refseq:NP_005366.2|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1904899"(positive regulation of hepatic stellate cell proliferation)|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|go:"GO:2000845"(positive regulation of testosterone secretion)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR012642(Mitotic Wos2)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|mint:P10242|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000118513(gene)|ensembl:ENST00000367814(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045624"(positive regulation of T-helper cell differentiation)|refseq:NP_001155128.1|dip:DIP-1057N|mint:MINT-6802171(identity) go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:1902396"(protein localization to bicellular tight junction)|refseq:NP_001104026.1|refseq:NP_001447.2|ensembl:ENSG00000196924(gene)|ensembl:ENST00000369850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097368"(establishment of Sertoli cell barrier)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:0046332"(SMAD binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|rcsb pdb:6EW1|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|dip:DIP-1136N|mint:MINT-6802175(identity) - - - figure legend:F4B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/11/28 2014/10/16 rogid:do/bvngcNTqnh1KZE4vDAtPP0749606 rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606 intact-crc:BDD3D46A55690ED4|rigid:j2goPOBaStqq2P1i9UOEBWiHih8 false flag tag:?-?(MINT-6802172)|mutation disrupting interaction:509-628(MINT-6802197) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P10242 uniprotkb:Q00610 intact:EBI-298355|uniprotkb:P78391|uniprotkb:P78392|uniprotkb:P78525|uniprotkb:P78526|uniprotkb:Q14023|uniprotkb:Q14024|uniprotkb:Q9UE83|uniprotkb:Q708E4|uniprotkb:Q708E7|ensembl:ENSP00000356788|uniprotkb:E9PNL6|uniprotkb:E9PI07|uniprotkb:E9PLZ5|uniprotkb:E9PNA4|uniprotkb:E9PRS2 intact:EBI-354967|intact:EBI-28974011|ensembl:ENSP00000269122|uniprotkb:Q6N0A0|uniprotkb:Q86TF2|uniprotkb:D3DU00 psi-mi:myb_human(display_long)|uniprotkb:MYB(gene name)|psi-mi:MYB(display_short)|uniprotkb:Proto-oncogene c-Myb(gene name synonym) psi-mi:clh1_human(display_long)|uniprotkb:Clathrin heavy chain on chromosome 17(gene name synonym)|uniprotkb:CLTC(gene name)|psi-mi:CLTC(display_short)|uniprotkb:CLH17(gene name synonym)|uniprotkb:KIAA0034(gene name synonym)|uniprotkb:CLTCL2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yamauchi et al. (2008) pubmed:18548008|imex:IM-9553|mint:MINT-6802025|doi:10.1038/emboj.2008.118 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7971131|mint:MINT-6802167|imex:IM-9553-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001155129.1|refseq:NP_001155130.1|refseq:NP_001155131.1|refseq:NP_001155132.1|refseq:NP_001123644.1|refseq:NP_001123645.1|refseq:NP_005366.2|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1904899"(positive regulation of hepatic stellate cell proliferation)|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|go:"GO:2000845"(positive regulation of testosterone secretion)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR012642(Mitotic Wos2)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|mint:P10242|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000118513(gene)|ensembl:ENST00000367814(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045624"(positive regulation of T-helper cell differentiation)|refseq:NP_001155128.1|dip:DIP-1057N|mint:MINT-6802171(identity) ensembl:ENSG00000141367(gene)|ensembl:ENST00000269122(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_004850.1|ensembl:ENSP00000269122|ensembl:ENST00000393043|ensembl:ENSP00000376763|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q00610|rcsb pdb:2XZG|rcsb pdb:4G55|rcsb pdb:6E4L|rcsb pdb:6QNN|rcsb pdb:6QNP|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9013420|reactome:R-HSA-9013424|mint:MINT-6802179(identity) - - - figure legend:F4B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/11/28 2014/10/16 rogid:do/bvngcNTqnh1KZE4vDAtPP0749606 rogid:oGsLXL5J5MHO+ronpDIG9hJ11sU9606 intact-crc:BDD3D46A55690ED4|rigid:j2goPOBaStqq2P1i9UOEBWiHih8 false flag tag:?-?(MINT-6802172)|mutation disrupting interaction:509-628(MINT-6802197) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P10242 uniprotkb:Q00610 intact:EBI-298355|uniprotkb:P78391|uniprotkb:P78392|uniprotkb:P78525|uniprotkb:P78526|uniprotkb:Q14023|uniprotkb:Q14024|uniprotkb:Q9UE83|uniprotkb:Q708E4|uniprotkb:Q708E7|ensembl:ENSP00000356788|uniprotkb:E9PNL6|uniprotkb:E9PI07|uniprotkb:E9PLZ5|uniprotkb:E9PNA4|uniprotkb:E9PRS2 intact:EBI-354967|intact:EBI-28974011|ensembl:ENSP00000269122|uniprotkb:Q6N0A0|uniprotkb:Q86TF2|uniprotkb:D3DU00 psi-mi:myb_human(display_long)|uniprotkb:MYB(gene name)|psi-mi:MYB(display_short)|uniprotkb:Proto-oncogene c-Myb(gene name synonym) psi-mi:clh1_human(display_long)|uniprotkb:Clathrin heavy chain on chromosome 17(gene name synonym)|uniprotkb:CLTC(gene name)|psi-mi:CLTC(display_short)|uniprotkb:CLH17(gene name synonym)|uniprotkb:KIAA0034(gene name synonym)|uniprotkb:CLTCL2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yamauchi et al. (2008) pubmed:18548008|imex:IM-9553|mint:MINT-6802025|doi:10.1038/emboj.2008.118 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7971182|mint:MINT-6802128|imex:IM-9553-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001155129.1|refseq:NP_001155130.1|refseq:NP_001155131.1|refseq:NP_001155132.1|refseq:NP_001123644.1|refseq:NP_001123645.1|refseq:NP_005366.2|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1904899"(positive regulation of hepatic stellate cell proliferation)|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|go:"GO:2000845"(positive regulation of testosterone secretion)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR012642(Mitotic Wos2)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|mint:P10242|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000118513(gene)|ensembl:ENST00000367814(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045624"(positive regulation of T-helper cell differentiation)|refseq:NP_001155128.1|dip:DIP-1057N|mint:MINT-6802132(identity) ensembl:ENSG00000141367(gene)|ensembl:ENST00000269122(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_004850.1|ensembl:ENSP00000269122|ensembl:ENST00000393043|ensembl:ENSP00000376763|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q00610|rcsb pdb:2XZG|rcsb pdb:4G55|rcsb pdb:6E4L|rcsb pdb:6QNN|rcsb pdb:6QNP|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9013420|reactome:R-HSA-9013424|mint:MINT-6802140(identity) - - - figure legend:F2D|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/11/28 2014/10/16 rogid:do/bvngcNTqnh1KZE4vDAtPP0749606 rogid:oGsLXL5J5MHO+ronpDIG9hJ11sU9606 intact-crc:81C3DC12BEFAD4EB|rigid:6tGNPlweEr8K1sKfWqSvl1+jnhk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)