#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9P0L9 uniprotkb:Q7Z443 intact:EBI-7956847|uniprotkb:Q9UPA2|uniprotkb:Q9UP35|intact:MINT-3973148|intact:MINT-4894275|uniprotkb:Q5W039|uniprotkb:O75972|ensembl:ENSP00000325296 intact:EBI-1059114|ensembl:ENSP00000480090 psi-mi:pk2l1_human(display_long)|uniprotkb:PKD2L1(gene name)|psi-mi:PKD2L1(display_short)|uniprotkb:PKD2L(gene name synonym)|uniprotkb:PKDL(gene name synonym)|uniprotkb:Polycystin-2L1(gene name synonym)|uniprotkb:Polycystin-L1(gene name synonym)|uniprotkb:Polycystin-L(gene name synonym)|uniprotkb:Polycystin-2 homolog(gene name synonym)|uniprotkb:TRPP3(gene name synonym) psi-mi:pk1l3_human(display_long)|uniprotkb:PKD1L3(gene name)|psi-mi:PKD1L3(display_short)|uniprotkb:Polycystin-1L3(gene name synonym)|uniprotkb:PC1-like 3 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Inada et al. (2008) pubmed:18535624|imex:IM-15018|mint:MINT-6743415 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7956841|mint:MINT-6743439|imex:IM-15018-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001240766.1|refseq:NP_057196.2|ensembl:ENSG00000107593(gene)|ensembl:ENST00000318222(transcript)|go:"GO:0001581"(detection of chemical stimulus involved in sensory perception of sour taste)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005272"(sodium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009415"(response to water)|go:"GO:0009986"(cell surface)|go:"GO:0015269"(calcium-activated potassium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033040"(sour taste receptor activity)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0050912"(detection of chemical stimulus involved in sensory perception of taste)|go:"GO:0050915"(sensory perception of sour taste)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060170"(ciliary membrane)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098662"(inorganic cation transmembrane transport)|interpro:IPR003915(Polycystic kidney disease type 2 protein)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR027359|mint:Q9P0L9|rcsb pdb:3TE3|rcsb pdb:4GIF|rcsb pdb:6DU8|mint:MINT-6743442(identity) refseq:NP_853514.1|ensembl:ENST00000620267(transcript)|go:"GO:0001581"(detection of chemical stimulus involved in sensory perception of sour taste)|go:"GO:0001822"(kidney development)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0016020"(membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0034703"(cation channel complex)|go:"GO:0043235"(receptor complex)|go:"GO:0050915"(sensory perception of sour taste)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071468"(cellular response to acidic pH)|interpro:IPR000203(GPS)|interpro:IPR000434(Polycystic kidney disease type 1 protein)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR001304(C-type lectin)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|ensembl:ENSG00000277481(gene)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR036392|interpro:IPR042060|mint:Q7Z443|mint:MINT-6743441(identity) - comment:mint|function:May function as a subunit of an ion channel and act as a transducer of calcium-mediated signaling - figure legend:F5C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2008/09/15 2014/10/16 rogid:IFhZjPsAOHneTxBdekU+KZ660Wc9606 rogid:ZqaeSYYnY9+umCi4EtRqZqey1a89606 intact-crc:ABE5A303AE92DE6E|rigid:x4xAS5vKTZg5lCGWyLw69TKTU2c false - ha tag:?-?(MINT-8019800)|mutation decreasing interaction:1-1056(MINT-6743475)|mutation decreasing interaction:179-606(MINT-6743472) - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0396"(predetermined participant)